A composite light adjustable intraocular lens comprises an acrylic diffractive intraocular lens, having a diffractive structure and haptics; and a silicone light adjustable lens, attached to the acrylic diffractive intraocular lens. The diffractive structure produces constructive interference in at least four consecutive diffractive orders corresponding a range of vision between near and distance vision, wherein the constructive interference produces a near focal point, a distance focal point corresponding to the base power of the ophthalmic lens, and an intermediate focal point between the near focal point and the distance focal point and wherein a diffraction efficiency of at least one of the diffractive orders is suppressed to less than ten percent.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/26 - Mélanges de matériaux macromoléculaires
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
C08F 220/18 - Esters des alcools ou des phénols monohydriques des phénols ou des alcools contenant plusieurs atomes de carbone avec l'acide acrylique ou l'acide méthacrylique
C08G 77/00 - Composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant du silicium, avec ou sans soufre, azote, oxygène ou carbone
C08G 77/14 - Polysiloxanes contenant du silicium lié à des groupes contenant de l'oxygène
2.
COMPACT ULTRAVIOLET LIGHT DELIVERY DEVICE FOR OPHTHALMIC PROCEDURES
A compact UV light delivery device comprises a UV LED, integrated into the compact UV light delivery device, to generate a UV beam; a homogenizing beam coupler, to receive the UV beam from the UV LED, and to homogenize the UV beam such that a measure of non-uniformity of the output homogenized beam is smaller than the measure of non-uniformity of the received UV beam; an illumination optics, to receive the homogenized beam and to forward it as an illumination beam; a spatial light modulator, to modulate the illumination beam into a modulated beam according to a procedure profile; a projection optics, to receive and to project the modulated beam as a projection beam through its objective into an eye of a patient; and a binocular-free imaging system, to image the eye of the patient via the same objective, and to present the image on a user interface.
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
G02B 26/08 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander la direction de la lumière
3.
COMPACT ULTRAVIOLET LIGHT DELIVERY DEVICE FOR OPHTHALMIC PROCEDURES
A compact UV light delivery device comprises a UV LED, integrated into the compact UV light delivery device, to generate a UV beam; a homogenizing beam coupler, to receive the UV beam from the UV LED, and to homogenize the UV beam such that a measure of non-uniformity of the output homogenized beam is smaller than the measure of non-uniformity of the received UV beam; an illumination optics, to receive the homogenized beam and to forward it as an illumination beam; a spatial light modulator, to modulate the illumination beam into a modulated beam according to a procedure profile; a projection optics, to receive and to project the modulated beam as a projection beam through its objective into an eye of a patient; and a binocular-free imaging system, to image the eye of the patient via the same objective, and to present the image on a user interface.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A compact UV light delivery device comprises a UV LED, integrated into the compact UV light delivery device, to generate a UV beam; a homogenizing beam coupler, to receive the UV beam from the UV LED, and to homogenize the UV beam such that a measure of non-uniformity of the output homogenized beam is smaller than the measure of non-uniformity of the received UV beam; an illumination optics, to receive the homogenized beam and to forward it as an illumination beam; a spatial light modulator, to modulate the illumination beam into a modulated beam according to a procedure profile; a projection optics, to receive and to project the modulated beam as a projection beam through its objective into an eye of a patient; and a binocular-free imaging system, to image the eye of the patient via the same objective, and to present the image on a user interface.
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A compact UV light delivery device comprises a UV LED, integrated into the compact UV light delivery device, to generate a UV beam; a homogenizing beam coupler, to receive the UV beam from the UV LED, and to homogenize the UV beam such that a measure of non-uniformity of the output homogenized beam is smaller than the measure of non-uniformity of the received UV beam; an illumination optics, to receive the homogenized beam and to forward it as an illumination beam; a spatial light modulator, to modulate the illumination beam into a modulated beam according to a procedure profile; a projection optics, to receive and to project the modulated beam as a projection beam through its objective into an eye of a patient; and a binocular-free imaging system, to image the eye of the patient via the same objective, and to present the image on a user interface.
A compact UV light delivery device comprises a UV LED, integrated into the compact UV light delivery device, to generate a UV beam; a homogenizing beam coupler, to receive the UV beam from the UV LED, and to homogenize the UV beam such that a measure of non-uniformity of the output homogenized beam is smaller than the measure of non-uniformity of the received UV beam; an illumination optics, to receive the homogenized beam and to forward it as an illumination beam; a spatial light modulator, to modulate the illumination beam into a modulated beam according to a procedure profile; a projection optics, to receive and to project the modulated beam as a projection beam through its objective into an eye of a patient; and a binocular-free imaging system, to image the eye of the patient via the same objective, and to present the image on a user interface.
A compact UV light delivery device comprises a UV LED, integrated into the compact UV light delivery device, to generate a UV beam; a homogenizing beam coupler, to receive the UV beam from the UV LED, and to homogenize the UV beam such that a measure of non-uniformity of the output homogenized beam is smaller than the measure of non-uniformity of the received UV beam; an illumination optics, to receive the homogenized beam and to forward it as an illumination beam; a spatial light modulator, to modulate the illumination beam into a modulated beam according to a procedure profile; a projection optics, to receive and to project the modulated beam as a projection beam through its objective into an eye of a patient; and a binocular-free imaging system, to image the eye of the patient via the same objective, and to present the image on a user interface.
A compact UV light delivery device comprises a UV LED, integrated into the compact UV light delivery device, to generate a UV beam; a homogenizing beam coupler, to receive the UV beam from the UV LED, and to homogenize the UV beam such that a measure of non-uniformity of the output homogenized beam is smaller than the measure of non-uniformity of the received UV beam; an illumination optics, to receive the homogenized beam and to forward it as an illumination beam; a spatial light modulator, to modulate the illumination beam into a modulated beam according to a procedure profile; a projection optics, to receive and to project the modulated beam as a projection beam through its objective into an eye of a patient; and a binocular-free imaging system, to image the eye of the patient via the same objective, and to present the image on a user interface.
B29D 11/00 - Fabrication d'éléments optiques, p. ex. lentilles ou prismes
G02B 27/09 - Mise en forme du faisceau, p. ex. changement de la section transversale, non prévue ailleurs
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
9.
COMPACT ULTRAVIOLET LIGHT DELIVERY DEVICE FOR OPHTHALMIC PROCEDURES
A compact UV light delivery device comprises a UV LED, integrated into the compact UV light delivery device, to generate a UV beam; a homogenizing beam coupler, to receive the UV beam from the UV LED, and to homogenize the UV beam such that a measure of non-uniformity of the output homogenized beam is smaller than the measure of non-uniformity of the received UV beam; an illumination optics, to receive the homogenized beam and to forward it as an illumination beam; a spatial light modulator, to modulate the illumination beam into a modulated beam according to a procedure profile; a projection optics, to receive and to project the modulated beam as a projection beam through its objective into an eye of a patient; and a binocular-free imaging system, to image the eye of the patient via the same objective, and to present the image on a user interface.
An autorefractor includes a point-like light source, to emit a light beam; a beam splitter, to direct the light beam; an aberration compensator optic, to receive the light beam from the beam splitter, to propagate the light beam with a compensating aberration to an eye of a patient, and to propagate a reflected light beam, reflected by the eye, to the beam splitter; wherein the beam splitter is configured to direct the reflected light beam, received from the aberration compensator optic; a camera, to receive the reflected light beam from the beam splitter, and to capture an image formed by the reflected light beam; and a controller, to determine a compensation indicator of the reflected light beam from the captured image, and to adjust the aberration compensator optic to improve the compensation indicator. In some embodiments, the above autorefractor can be combined with a multi-channel subjective refractor.
H04N 23/56 - Caméras ou modules de caméras comprenant des capteurs d'images électroniquesLeur commande munis de moyens d'éclairage
H04N 23/68 - Commande des caméras ou des modules de caméras pour une prise de vue stable de la scène, p. ex. en compensant les vibrations du boîtier de l'appareil photo
A multi-channel subjective refractor can comprise a first display to generate a first image; a second display to generate a second image; a first channel to refract the first image with a first channel refraction; a second channel to refract the second image with a second channel refraction; a beam combiner to receive and to combine the first image and the second image; and a shared channel, to receive the first image and the second image from the beam combiner to refract, in combination with the first channel, the first image with a first refraction; to refract, in combination with the second channel, the second image with a second refraction; and to present the first image with the first refraction and the second image with the second refraction to an eye simultaneously.
A61B 3/028 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient pour examen d'acuité visuelleAppareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient pour la détermination de la réfraction, p. ex. phoromètres
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A multi-channel subjective refractor can comprise a first display to generate a first image; a second display to generate a second image; a first channel to refract the first image with a first channel refraction; a second channel to refract the second image with a second channel refraction; a beam combiner to receive and to combine the first image and the second image; and a shared channel, to receive the first image and the second image from the beam combiner to refract, in combination with the first channel, the first image with a first refraction; to refract, in combination with the second channel, the second image with a second refraction; and to present the first image with the first refraction and the second image with the second refraction to an eye simultaneously.
A61B 3/028 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient pour examen d'acuité visuelleAppareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient pour la détermination de la réfraction, p. ex. phoromètres
A61B 3/18 - Agencement de plusieurs appareils pour tester ou examiner les yeux
A multi-channel subjective refractor comprises a first channel to refract a first image, generated by a first display, with a first channel refraction; a second channel to refract a second image, generated by a second display, with a second channel refraction; a beam combiner to combine the first image and the second image; and a shared channel to present the first image with the first refraction and the second image with the second refraction to an eye simultaneously. A method of operating this multi-channel subjective refractor comprises the steps of generating a first image with a first refraction and a second image with a second refraction with the multi-channel subjective refractor; presenting the first image with the first refraction and the second image with the second refraction simultaneously for an eye of a patient; and prompting the patient to identify the sharper of the first image and the second image.
A61B 3/028 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient pour examen d'acuité visuelleAppareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient pour la détermination de la réfraction, p. ex. phoromètres
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
In some embodiments of an enhanced monofocal intraocular lens (EMF IOL), an optical power of the EMF IOL is characterized by a base optical power for distance vision, consistent with a monofocal lens; and an additive add-power structure for near vision, including a central add-power ring around an optical axis of the IOL; and an axial power hole at the optical axis of the IOL. In embodiments, the add-power structure is induced by an approximate super Gaussian optical path difference, the super Gaussian having a radial coordinate raised to a power greater than two in its exponential. In some EMF IOLS, an optical path difference of the EMF IOL is characterized by a base wavefront for distance vision; and an additive add-power structure wavefront for near vision, approximately characterized by a super Gaussian, having a radial coordinate r raised to a power greater than two in its exponential.
In some embodiments of an enhanced monofocal intraocular lens (EMF IOL), an optical power of the EMF IOL is characterized by a base optical power for distance vision, consistent with a monofocal lens; and an additive add-power structure for near vision, including a central add-power ring around an optical axis of the IOL; and an axial power hole at the optical axis of the IOL. In embodiments, the add-power structure is induced by an approximate super Gaussian optical path difference, the super Gaussian having a radial coordinate raised to a power greater than two in its exponential. In some EMF IOLs, an optical path difference of the EMF IOL is characterized by a base wavefront for distance vision; and an additive add-power structure wavefront for near vision, approximately characterized by a super Gaussian, having a radial coordinate r raised to a power greater than two in its exponential.
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/26 - Mélanges de matériaux macromoléculaires
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
17.
LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5 - 20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/26 - Mélanges de matériaux macromoléculaires
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
20.
LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/26 - Mélanges de matériaux macromoléculaires
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
22.
LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
A61L 27/16 - Matériaux macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/26 - Mélanges de matériaux macromoléculaires
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
23.
LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/26 - Mélanges de matériaux macromoléculaires
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
24.
LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
Light Adjustable Lenses are described with a caged photoinitator and advanced polymerization control that greatly suppress unintended optical power drift in these lenses. Some Light Adjustable Lenses comprise a polymer silicone network, molded in the presence of a mobile macromer and an ultraviolet absorber; and a cage-photoinitiator complex; wherein a caged photoinitiator can be freed from a cage by a first photon of a first illumination; the free photoinitiator can be activated by a second photon of a second illumination; and the activated photoinitiator is capable of inducing a polymerization reaction of the mobile macromer, leading to a changing of an optical power of the LAL.
G02B 1/04 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances organiques, p. ex. plastiques
G02B 1/14 - Revêtements protecteurs, p. ex. revêtements durs
26.
LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5 - 20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non- switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5 - 20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
Light Adjustable Lenses are described with a caged photoinitator and advanced polymerization control that greatly suppress unintended optical power drift in these lenses. Some Light Adjustable Lenses comprise a polymer silicone network, molded in the presence of a mobile macromer and an ultraviolet absorber; and a cage-photoinitiator complex; wherein a caged photoinitiator can be freed from a cage by a first photon of a first illumination; the free photoinitiator can be activated by a second photon of a second illumination; and the activated photoinitiator is capable of inducing a polymerization reaction of the mobile macromer, leading to a changing of an optical power of the LAL.
C08F 2/50 - Polymérisation amorcée par énergie ondulatoire ou par rayonnement corpusculaire par la lumière ultraviolette ou visible avec des agents sensibilisants
C07C 49/788 - Cétones comportant un groupe cétone lié à un cycle aromatique à six chaînons polycycliques des groupes cétone étant liés à un système cyclique condensé
C07C 49/792 - Cétones comportant un groupe cétone lié à un cycle aromatique à six chaînons polycycliques contenant des cycles autres que des cycles aromatiques à six chaînons
Embodiments of a modulable absorption light adjustable lens (MALAL) comprise a light adjustable lens that is capable of changing its optical properties upon an adjusting irradiation, including a photo-modifiable material; and a modulable absorption front protection layer, including a modulable absorption compound whose absorption properties can be modulated with a modulating stimulus. Other embodiments include a method of adjusting an optical property of a modulable absorption light adjustable lens, the method comprising: reducing an absorption of a modulable absorption compound of a modulable absorption front protection layer of the MALAL by a modulating stimulus, the MALAL having been previously implanted into an eye; and changing an optical property of a light adjustable lens of the MALAL by applying an adjusting irradiation.
A composite light adjustable intraocular lens can include an acrylic intraocular insert; a silicone-based light adjustable lens, attached to the acrylic intraocular insert with an adhesion promoter; and haptics; wherein the adhesion promoter includes a first orthogonal functional group, configured to bond with an acrylic component of the acrylic intraocular insert; and a second orthogonal functional group, configured to bond with a silicone component of the silicone-based light adjustable lens.
A composite light adjustable intraocular lens comprises an acrylic diffractive intraocular lens, having a diffractive structure and haptics; and a silicone light adjustable lens, attached to the acrylic diffractive intraocular lens. The diffractive structure produces constructive interference in at least four consecutive diffractive orders corresponding a range of vision between near and distance vision, wherein the constructive interference produces a near focal point, a distance focal point corresponding to the base power of the ophthalmic lens, and an intermediate focal point between the near focal point and the distance focal point and wherein a diffraction efficiency of at least one of the diffractive orders is suppressed to less than ten percent.
Embodiments of a modulable absorption light adjustable lens (MALAL) comprise a light adjustable lens that is capable of changing its optical properties upon an adjusting irradiation, including a photo-modifiable material; and a modulable absorption front protection layer, including a modulable absorption compound whose absorption properties can be modulated with a modulating stimulus. Other embodiments include a method of adjusting an optical property of a modulable absorption light adjustable lens, the method comprising: reducing an absorption of a modulable absorption compound of a modulable absorption front protection layer of the MALAL by a modulating stimulus, the MALAL having been previously implanted into an eye; and changing an optical property of a light adjustable lens of the MALAL by applying an adjusting irradiation.
A cartridge of an intraocular lens (IOL) inserter includes an insertion nozzle, having a distal insertion channel; an IOL-folding stage, having a proximal insertion channel; and a haptic protection structure to protect a trailing haptic of the IOL from damage by a push-rod of the inserter. The haptic protection structure includes a proximal guiding groove in the IOL-folding stage, or a distal guiding groove in the insertion nozzle. The haptic protection structure further includes a trailing-haptic notch, to guide a trailing haptic protruding from the proximal guiding groove; and a trailing-haptic retainer, to secure the trailing haptic out of the proximal insertion channel. An intraocular lens inserter includes an inserter cylinder; a push-rod in the inserter cylinder; a cartridge-receiving insertion tip, to receive a cartridge that includes an insertion nozzle, having a distal insertion channel; an intra-ocular lens-folding stage, having a proximal insertion channel; and a haptic protection structure.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
medical apparatus and instruments for use in connection with vision correcting intraocular lenses; intraocular lenses; lenses for surgical implantation; light-adjustable intraocular lens; intraocular lenses with ultraviolet protective technology; ultraviolet protective intraocular lenses. conducting research and clinical trials for others relating to medical devices and pharmaceuticals in the fields of ophthalmology and optometry. ophthalmology services; optometry services.
A composite light adjustable intraocular lens can include an acrylic intraocular insert; a silicone-based light adjustable lens, attached to the acrylic intraocular insert with an adhesion promoter; and haptics; wherein the adhesion promoter includes a first orthogonal functional group, configured to bond with an acrylic component of the acrylic intraocular insert; and a second orthogonal functional group, configured to bond with a silicone component of the silicone-based light adjustable lens.
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
C08F 220/00 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et un seul étant terminé par un seul radical carboxyle ou un sel, anhydride, ester, amide, imide ou nitrile
A composite light adjustable intraocular lens comprises an acrylic diffractive intraocular lens, having a diffractive structure and haptics; and a silicone light adjustable lens, attached to the acrylic diffractive intraocular lens. The diffractive structure produces constructive interference in at least four consecutive diffractive orders corresponding a range of vision between near and distance vision, wherein the constructive interference produces a near focal point, a distance focal point corresponding to the base power of the ophthalmic lens, and an intermediate focal point between the near focal point and the distance focal point and wherein a diffraction efficiency of at least one of the diffractive orders is suppressed to less than ten percent.
A61L 27/26 - Mélanges de matériaux macromoléculaires
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
C08F 220/18 - Esters des alcools ou des phénols monohydriques des phénols ou des alcools contenant plusieurs atomes de carbone avec l'acide acrylique ou l'acide méthacrylique
C08G 77/14 - Polysiloxanes contenant du silicium lié à des groupes contenant de l'oxygène
intraocular lenses; lenses in the nature of intraocular prosthesis for surgical implantation; light-adjustable intraocular lens; intraocular lenses with ultraviolet protective technology; ultraviolet protective intraocular lenses
43.
LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER
Embodiments of a modulable absorption light adjustable lens (MALAL) comprise a light adjustable lens that is capable of changing its optical properties upon an adjusting irradiation, including a photo-modifiable material; and a modulable absorption front protection layer, including a modulable absorption compound whose absorption properties can be modulated with a modulating stimulus. Other embodiments include a method of adjusting an optical property of a modulable absorption light adjustable lens, the method comprising: reducing an absorption of a modulable absorption compound of a modulable absorption front protection layer of the MALAL by a modulating stimulus, the MALAL having been previously implanted into an eye; and changing an optical property of a light adjustable lens of the MALAL by applying an adjusting irradiation.
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61F 2/14 - Parties d'yeux, p. ex. cristallins ou implants de cornéeYeux artificiels
A61G 3/00 - Point de vue ambulance dans les véhiculesVéhicules avec des dispositions particulières pour transporter les personnes handicapées ou leurs moyens de transport personnels, p. ex. pour faciliter l'accès ou pour charger des chaises roulantes
Embodiments of a modulable absorption light adjustable lens (MALAL) comprise a light adjustable lens that is capable of changing its optical properties upon an adjusting irradiation, including a photo-modifiable material; and a modulable absorption front protection layer, including a modulable absorption compound whose absorption properties can be modulated with a modulating stimulus. Other embodiments include a method of adjusting an optical property of a modulable absorption light adjustable lens, the method comprising: reducing an absorption of a modulable absorption compound of a modulable absorption front protection layer of the MALAL by a modulating stimulus, the MALAL having been previously implanted into an eye; and changing an optical property of a light adjustable lens of the MALAL by applying an adjusting irradiation.
A light adjustable lens illumination system comprises an illumination source, for generating a light beam; a light delivery system, for projecting the light beam onto a Light Adjustable Lens (LAL), implanted into an eye, wherein a fraction of the light beam propagates past the LAL to a retina of the eye; and a protective beam-shaper, for shaping the light beam to have an intensity pattern with a relative central intensity reduction that varies along an axis; wherein the relative central intensity reduction at the retina is greater than the relative central intensity reduction at a LAL plane.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes en utilisant des lasers
A61B 3/125 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes avec des lentilles de contact
46.
METHOD OF ADJUSTING A BLENDED EXTENDED DEPTH OF FOCUS LIGHT ADJUSTABLE LENS WITH LATERALLY OFFSET AXES
A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis, A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.
47.
MULTI-FACTOR CONTROL SYSTEM FOR OPHTHALMIC REFRACTION MODIFICATION
An ophthalmic system comprises a Refraction Modification System for modifying a refraction of an eye, in response to refraction modification parameters: and a Prescription Engine, for generating the refraction modification parameters for the Refraction Modification System by a Prescription Algorithm that combines one or more diagnostic factor, determined by an ophthalmic diagnostic device, and one or more patient factor. Correspondingly, a method of operating an ophthalmic system comprises receiving one or more diagnostic factor by a Prescription Engine, determined by an ophthalmic diagnostic device; receiving one or more patient factor by the Prescription Engine; and generating refraction modification parameters by the Prescription Engine for a Refraction Modification System by combining the one or more diagnostic factor and the one or more patient factor with a Prescription Algorithm; wherein the Refraction Modification System is configured for modifying a refraction of an eye, in response to the generated refraction modification parameters.
An ophthalmic system comprises a Refraction Modification System for modifying a refraction of an eye, in response to refraction modification parameters; and a Prescription Engine, for generating the refraction modification parameters for the Refraction Modification System by a Prescription Algorithm that combines one or more diagnostic factor, determined by an ophthalmic diagnostic device, and one or more patient factor. Correspondingly, a method of operating an ophthalmic system comprises receiving one or more diagnostic factor by a Prescription Engine, determined by an ophthalmic diagnostic device; receiving one or more patient factor by the Prescription Engine; and generating refraction modification parameters by the Prescription Engine for a Refraction Modification System by combining the one or more diagnostic factor and the one or more patient factor with a Prescription Algorithm; wherein the Refraction Modification System is configured for modifying a refraction of an eye, in response to the generated refraction modification parameters.
A61B 3/103 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p. ex. réfractomètres, skiascopes
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 3/028 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient pour examen d'acuité visuelleAppareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient pour la détermination de la réfraction, p. ex. phoromètres
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A Light Adjustable Lens (LAL) Tracker comprises an Imaging System, for creating a LAL image by imaging a LAL implanted into an eye; and an Image Recognition System, coupled to the Imaging System, for determining a disk cross-correlator with the LAL image; determining an edge cross-correlator with the LAL image: and determining a LAL position by determining a combined cross-correlator from the disk cross-correlator and the edge cross-correlator. A Tracking-based Illumination Control System comprises the LAL Tracker for tracking a LAL implanted in an eye, including an Imaging System, and an Image Recognition System; and an Illumination Controller, coupled to the LAL Tracker, configured for determining a LAL misalignment factor, corresponding to a LAL misalignment that characterizes a misalignment of the LAL position with a LAL illumination pattern, and generating an illumination control signal in relation to the determined LAL misalignment factor.
A61B 3/11 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la distance interpupillaire ou le diamètre de la pupille
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A Light Adjustable Lens (LAL) Tracker comprises an Imaging System, for creating a LAL image by imaging a LAL implanted into an eye; and an Image Recognition System, coupled to the Imaging System, for determining a disk cross-correlator with the LAL image; determining an edge cross-correlator with the LAL image; and determining a LAL position by determining a combined cross-correlator from the disk cross-correlator and the edge cross-correlator. A Tracking-based Illumination Control System comprises the LAL Tracker for tracking a LAL implanted in an eye, including an Imaging System, and an Image Recognition System; and an Illumination Controller, coupled to the LAL Tracker, configured for determining a LAL misalignment factor, corresponding to a LAL misalignment that characterizes a misalignment of the LAL position with a LAL illumination pattern, and generating an illumination control signal in relation to the determined LAL misalignment factor.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
A61F 2/14 - Parties d'yeux, p. ex. cristallins ou implants de cornéeYeux artificiels
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A Light Adjustable Lens (LAL) Tracker comprises an Imaging System, for creating a LAL image by imaging a LAL implanted into an eye; and an Image Recognition System, coupled to the Imaging System, for determining a disk cross-correlator with the LAL image; determining an edge cross-correlator with the LAL image; and determining a LAL position by determining a combined cross-correlator from the disk cross-correlator and the edge cross-correlator. A Tracking-based Illumination Control System comprises the LAL Tracker for tracking a LAL implanted in an eye, including an Imaging System, and an Image Recognition System; and an Illumination Controller, coupled to the LAL Tracker, configured for determining a LAL misalignment factor, corresponding to a LAL misalignment that characterizes a misalignment of the LAL position with a LAL illumination pattern, and generating an illumination control signal in relation to the determined LAL misalignment factor.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A Light Adjustable Lens (LAL) Tracker comprises an Imaging System, for creating a LAL image by imaging a LAL implanted into an eye; and an Image Recognition System, coupled to the Imaging System, for determining a disk cross-correlator with the LAL image; determining an edge cross-correlator with the LAL image; and determining a LAL position by determining a combined cross-correlator from the disk cross-correlator and the edge cross-correlator. A Tracking-based Illumination Control System comprises the LAL Tracker for tracking a LAL implanted in an eye, including an Imaging System, and an Image Recognition System; and an Illumination Controller, coupled to the LAL Tracker, configured for determining a LAL misalignment factor, corresponding to a LAL misalignment that characterizes a misalignment of the LAL position with a LAL illumination pattern, and generating an illumination control signal in relation to the determined LAL misalignment factor.
G06T 7/70 - Détermination de la position ou de l'orientation des objets ou des caméras
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
H05B 47/105 - Commande de la source lumineuse en réponse à des paramètres détectés
53.
Adjustable optical elements with enhanced ultraviolet protection
The invention relates to novel optical elements having improved UV protection. The optical element comprises a light adjustable optical element with a UV absorbent layer applied to at least one surface of the optical element. The invention is particularly useful in light adjustable intraocular lenses.
An ophthalmic visualization system includes a rear illumination system, to generate and to project a rear illumination light onto a retina of an eye that has an intraocular lens (IOL) implanted into the eye, so that the rear illumination light reflects from the retina as a reflected illumination light, wherein a central portion of the reflected illumination light propagates through the IOL to form an IOL-focused illumination light, and a peripheral portion of the reflected illumination light propagates around the IOL to form a peripheral illumination light; an optic, to receive the IOL-focused illumination light and the peripheral illumination light from the eye, and to transmit the received illumination lights; an aperture slop, to stop the transmitted peripheral illumination light, and to allow the IOL-focused illumination light to pass through; and an imaging system, to form an isolated IOL image based on the transmitted IOL-focused illumination light.
An ophthalmic visualization system includes a rear illumination system, to generate and to project a rear illumination light onto a retina of an eye that has an intraocular lens (IOL) implanted into the eye, so that the rear illumination light reflects from the retina as a reflected illumination light, wherein a central portion of the reflected illumination light propagates through the IOL to form an IOL-focused illumination light, and a peripheral portion of the reflected illumination light propagates around the IOL to form a peripheral illumination light; an optic, to receive the IOL- focused illumination light and the peripheral illumination light from the eye, and to transmit the received illumination lights; an aperture stop, to stop the transmitted peripheral illumination light, and to allow the IOL-focused illumination light to pass through; and an imaging system, to form an isolated IOL image based on the transmitted IOL-focused illumination light.
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
56.
PATIENT INTERFACE FOR LIGHT ADJUSTABLE INTRAOCULAR LENS IRRADIATION SYSTEM
In embodiments, a light adjustable lens irradiation system for a light adjustable lens irradiation system, comprises an irradiation light source, for generating a UV light beam; an optical system, for directing the UV light beam towards a light adjustable intraocular lens, implanted into an eye of a patient; and a patient interface, coupled to the optical system, for stabilizing the eye relative to the optical system, to achieve an alignment of the light adjustable intraocular lens and the UV light beam.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
In embodiments, a light adjustable lens irradiation system for a light adjustable lens irradiation system, comprises an irradiation light source, for generating a UV light beam; an optical system, for directing the UV light beam towards a light adjustable intraocular lens, implanted into an eye of a patient; and a patient interface, coupled to the optical system, for stabilizing the eye relative to the optical system, to achieve an alignment of the light adjustable intraocular lens and the UV light beam.
B29D 11/00 - Fabrication d'éléments optiques, p. ex. lentilles ou prismes
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux
A61N 5/067 - Thérapie par radiations utilisant un rayonnement lumineux utilisant un rayonnement laser
58.
Method of adjusting a blended extended depth of focus light adjustable lens with laterally offset axes
A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
59.
Blended extended depth of focus light adjustable lens with laterally offset axes
A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
RIRLIRLRR-1). Some variations of the MF-IOL include stimulus-orientable optically anisotropic constituents. Some classes of the MF-IOL include a self-assembling optically anisotropic compound. A corresponding method of a making a MF-IOL is comprising providing stimulus-orientable optically anisotropic constituents as part of an intraocular lens; orienting the optically anisotropic constituents by applying a non-stretching stimulus; and locking-in the oriented optically anisotropic constituents to form the multifocal intraocular lens.
A61F 2/14 - Parties d'yeux, p. ex. cristallins ou implants de cornéeYeux artificiels
G02B 1/08 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances polarisantes
R−1). Some variations of the MF-IOL include stimulus-orientable optically anisotropic constituents. Some classes of the MF-IOL include a self-assembling optically anisotropic compound. A corresponding method of making a MF-IOL is comprising providing stimulus-orientable optically anisotropic constituents as part of an intraocular lens; orienting the optically anisotropic constituents by applying a non-stretching stimulus; and locking-in the oriented optically anisotropic constituents to form the multifocal intraocular lens.
A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
G02B 1/08 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances polarisantes
A composite light adjustable intraocular lens, can include an intraocular lens (IOL), a light adjustable lens, attached to the intraocular lens, and haptics. In some cases, a composite light adjustable intraocular lens can include an intraocular lens, and haptics, attached to the IOL with light-adjustable hinges. A method of adjusting an implanted composite light adjustable intraocular lens can include planning a targeted optical outcome of an implantation of the composite light adjustable intraocular lens into an eye; implanting the composite light adjustable intraocular lens into the eye; performing a diagnostic measurement to evaluate an implanted optical outcome of the implantation; determining a correction based on a comparison of the planned optical outcome and the implanted optical outcome; and applying a stimulus to adjust an optical characteristic of the composite light adjustable intraocular lens to induce the determined correction.
A composite light adjustable intraocular lens, can include an intraocular lens (IOL), a light adjustable lens, attached to the intraocular lens, and haptics. In some cases, a composite light adjustable intraocular lens can include an intraocular lens, and haptics, attached to the IOL with light-adjustable hinges. A method of adjusting an implanted composite light adjustable intraocular lens can include planning a targeted optical outcome of an implantation of the composite light adjustable intraocular lens into an eye; implanting, the composite light adjustable intraocular lens into the eye; performing a diagnostic measurement to evaluate an implanted optical outcome of the implantation; determining a correction based on a comparison of the planned optical outcome and the implanted optical outcome; and applying a stimulus to adjust an optical characteristic of the composite light adjustable intraocular lens to induce the determined correction.
A color-apodized intraocular lens includes a lens center, with a center-transmittance to transmit an incident light; a lens annulus, surrounding the lens center, configured to selectively attenuate the incident light according to a radius- and wavelength-dependent annulus- transmittance, wherein the annulus-transmittance is less than the center-transmittance, in a short wavelength spectral range; and haptics, extending from the lens annul us. A method of making a color-apodized intraocular lens includes creating an intraocular lens moid using a base-polymer, the intraocular lens having a lens center, with a center-transmittance to transmit an incident light; a lens annulus, surrounding the lens center, configured to selectively attenuate the incident light according to a radius and wavelength-dependent anmims-transmittance, wherein the annulus-transmittance is less than the center-transmittance in a short wavelength spectral range; forming haptics, extending from the lens annulus; and applying a stimulus to the intraocular lens mold to form the color-apodized intraocular lens.
A color-apodized intraocular lens includes a lens center, with a center-transmittance to transmit an incident light; a lens annul us, surrounding the lens center, configured to selectively attenuate the incident light according to a radius- and wavelength-dependent annulus-transmittance, wherein the annulus-transmittance is less than the center-transmittance, in a short wavelength spectral range; and haptics, extending from the lens annulus. A method of making a color-apodized intraocular lens includes creating an intraocular lens mold using a base-polymer, the intraocular lens having a lens center, with a center-transmittance to transmit an incident light; a lens annulus, surrounding the lens center, configured to selectively attenuate the incident light according to a radius and wavelength-dependent annulus-transmittance, wherein the annulus-transmittance is less than the center-transmittance in a short wavelength spectral range; forming haptics, extending from the lens annulus; and applying a stimulus to the intraocular lens mold to form the color-apodized intraocular lens.
A method for adjusting a light adjustable lens in an optical system includes providing a light adjustable lens in an optical system; providing an ultraviolet light source to generate an ultraviolet light; and irradiating the generated ultraviolet light with a light delivery system onto the light adjustable lens with a center wavelength and with a spatial irradiance profile to change a dioptric power of the light adjustable lens by changing a refraction of the light adjustable lens in a refraction-change zone, thereby causing a wavefront sag, defined as half of a product of the change of the dioptric power and the square of a radius of the refraction-change zone, to be within 28% of its maximum over an ultraviolet spectrum.
B29D 11/00 - Fabrication d'éléments optiques, p. ex. lentilles ou prismes
B29D 11/02 - Yeux artificiels en matériaux plastiques organiques
B29K 683/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du silicium avec ou sans soufre, azote, oxygène ou carbone pour des pièces préformées, p. ex. pour des inserts
67.
INTRAOCULAR LENS INSERTER CARTRIDGE WITH AN IOL-GUIDING STRUCTRURE
A cartridge of an intraocular lens inserter comprises an insertion nozzle, having a distal insertion channel; an infra-ocular lens (IOL)-folding stage, to receive and to fold an IOL, prox imal to the insertion nozzle, and having a proximal insertion channel; and an SOL-guIding structure. The iOL-guiding staicture can inckde a first proximal guiding groove, or a first proximal guiding rib, or both, formed in the lOL-foiding stage. An intraocular leas inserter comprises an inserter cylinder; a push-rod, partially in the inserter cylinder: a cartridge- receiving insertion end, to receive a cartridge that includes an insertion nozzle, having a distal insertion channel; an iOL-faidiog stage, proximal to the insertion nozzle, having a proximal insertion channel; and an lOL-guiding structure.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
68.
Intraocular lens inserter cartridge with an IOL-guiding structure
A cartridge of an intraocular lens inserter comprises an insertion nozzle, having a distal insertion channel; an intra-ocular lens (IOL)-folding stage, to receive and to fold an IOL, proximal to the insertion nozzle, and having a proximal insertion channel; and an IOL-guiding structure. The IOL-guiding structure can include a first proximal guiding groove, or a first proximal guiding rib, or both, formed in the IOL-folding stage. An intraocular lens inserter comprises an inserter cylinder; a push-rod, partially in the inserter cylinder; a cartridge-receiving insertion end, to receive a cartridge that includes an insertion nozzle, having a distal insertion channel; an IOL-folding stage, proximal to the insertion nozzle, having a proximal insertion channel; and an IOL-guiding structure.
A cartridge of an intraocular lens (IOL) inserter includes an insertion nozzle, having a distal insertion channel; an IOL- folding stage, having a proximal insertion channel; and a haptic protection structure to protect a trailing haptic of the IOL from damage- by a push-rod of the inserter. The haptic protection structure includes a proximal, guiding groove in the IOL-folding stage, or a distal guiding groove in the insertion nozzle. The haptic protection structure further includes a trailing-haptic notch, to guide a trailing haptic protruding from the proximal guiding groove; and a trailing-haptic retainer, to secure the trailing haptic out of the proximal insertion channel. An intraocular lens inserter includes an inserter cylinder; a push-rod in the inserter cylinder; a cartridge-receiving insertion tip, to receive a cartridge that includes an insertion nozzle, having a distal insertion channel; an intra~ocular lens-folding stage, having a proximal insertion channel; aid a haptic protection structure.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Intra-ocular lenses; intraocular lens biometers; intraocular lenses; lenses for surgical implantation; prosthetic intraocular implants; surgical and medical instruments and apparatus for use in ophthalmology; ocular implants; optical articles for medical purposes; optical devices for medical diagnostic use; optical inspection apparatus for medical diagnostic use; artificial lenses for implantation in the eye; eye pads for surgical use; eye shields for medical use; eye trays for medical use; corneal shields; medical devices related to the eye; diagnostic scopes and meters for testing intraocular optics; corneal inlays. Conducting research and clinical trials for others relating to medical devices and pharmaceuticals in the field of ophthalmology; research, design, development and laboratory services relating to ophthalmology, pharmaceuticals and ocular surgery; medical research and development; laboratory services; design and development of apparatus, instruments and devices for ophthalmological use; development of apparatus, instruments and devices for the detection, diagnosis, management and treatment of eye disease; design and development of ophthalmoscopes; information, advisory and consultancy services relating to the aforesaid. Ophthalmology services; surgical, diagnostic and therapeutic services relating to the eye and eye care; eye care services; medical aftercare services relating to the provision of optical products; consultancy, advice and information services relating to the eyes, eye testing and eye surgery; information and advisory services relating to the care of the eyes; optician services; ophthalmic and optometrist services; information, advisory and consultancy services relating to the aforesaid.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Intra-ocular lenses; intraocular lens biometers; intraocular lenses; lenses for surgical implantation; prosthetic intraocular implants; surgical and medical instruments and apparatus for use in ophthalmology; ocular implants; optical articles for medical purposes; optical devices for medical diagnostic use; optical inspection apparatus for medical diagnostic use; artificial lenses for implantation in the eye; eye pads for surgical use; eye shields for medical use; eye trays for medical use; corneal shields; medical devices related to the eye; diagnostic scopes and meters for testing intraocular optics; corneal inlays. Conducting research and clinical trials for others relating to medical devices and pharmaceuticals in the field of ophthalmology; research, design, development and laboratory services relating to ophthalmology, pharmaceuticals and ocular surgery; medical research and development; laboratory services; design and development of apparatus, instruments and devices for ophthalmological use; development of apparatus, instruments and devices for the detection, diagnosis, management and treatment of eye disease; design and development of ophthalmoscopes; information, advisory and consultancy services relating to the aforesaid. Ophthalmology services; surgical, diagnostic and therapeutic services relating to the eye and eye care; eye care services; medical aftercare services relating to the provision of optical products; consultancy, advice and information services relating to the eyes, eye testing and eye surgery; information and advisory services relating to the care of the eyes; optician services; ophthalmic and optometrist services; information, advisory and consultancy services relating to the aforesaid.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Intra-ocular lenses; Intraocular lens biometers; Intraocular lenses; Lenses for surgical implantation; Prosthetic intraocular implants; surgical and medical instruments and apparatus for use in ophthalmology; ocular implants; optical articles for medical purposes; optical devices for medical diagnostic use; optical inspection apparatus for medical diagnostic use; artificial lenses for implantation in the eye; eye pads for surgical use; eye shields for medical use; eye trays for medical use; corneal shields; medical devices related to the eye; diagnostic scopes and meters for testing intraocular optics; corneal inlays. Conducting research and clinical trials for others relating to medical devices and pharmaceuticals in the field of ophthalmology; research, design, development and laboratory services relating to ophthalmology, pharmaceuticals and ocular surgery; medical research and development; laboratory services; design and development of apparatus, instruments and devices for ophthalmological use; development of apparatus, instruments and devices for the detection, diagnosis, management and treatment of eye disease; design and development of ophthalmoscopes; information, advisory and consultancy services relating to the aforesaid. Ophthalmology services; surgical, diagnostic and therapeutic services relating to the eye and eye care; eye care services; medical aftercare services relating to the provision of optical products; consultancy, advice and information services relating to the eyes, eye testing and eye surgery; information and advisory services relating to the care of the eyes; optician services; ophthalmic and optometrist services; information, advisory and consultancy services relating to the aforesaid.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Intra-ocular lenses; Intraocular lens biometers; Intraocular lenses; Lenses for surgical implantation; Prosthetic intraocular implants; surgical and medical instruments and apparatus for use in ophthalmology; ocular implants; optical articles for medical purposes; optical devices for medical diagnostic use; optical inspection apparatus for medical diagnostic use; artificial lenses for implantation in the eye; eye pads for surgical use; eye shields for medical use; eye trays for medical use; corneal shields; medical devices related to the eye; diagnostic scopes and meters for testing intraocular optics; corneal inlays. Conducting research and clinical trials for others relating to medical devices and pharmaceuticals in the field of ophthalmology; research, design, development and laboratory services relating to ophthalmology, pharmaceuticals and ocular surgery; medical research and development; laboratory services; design and development of apparatus, instruments and devices for ophthalmological use; development of apparatus, instruments and devices for the detection, diagnosis, management and treatment of eye disease; design and development of ophthalmoscopes; information, advisory and consultancy services relating to the aforesaid. Ophthalmology services; surgical, diagnostic and therapeutic services relating to the eye and eye care; eye care services; medical aftercare services relating to the provision of optical products; consultancy, advice and information services relating to the eyes, eye testing and eye surgery; information and advisory services relating to the care of the eyes; optician services; ophthalmic and optometrist services; information, advisory and consultancy services relating to the aforesaid.
75.
METHOD FOR MODIFYING POWER OF LIGHT ADJUSTABLE LENS
A method for adjusting a light, adjustable lens m an optical system includes providing a light adjustable lens in an optical system; providing an ultraviolet light source to generate an ultraviolet light; aid irradiating die generated ultraviolet light with a light delivery system onto the light adjustable lens with a center wavelength and with a spatial irradiance profile to change a dioptric power of the light adjustable lens by changing a refraction of the light adjustable lens in a refraction-change zone, thereby causing a wavefront sag, defined as half of a product of the change of the dioptric power and the square of a radius of the refraction-change zone, to be within 10% of its maximum over an ultraviolet spectrum.
A method for adjusting a light adjustable lens in an optical system includes providing a light adjustable lens in an optical system; providing an ultraviolet light source to generate an ultraviolet light; and irradiating the generated ultraviolet light with a light delivery system onto the light adjustable lens with a center wavelength and with a spatial irradiance profile to change a dioptric power of the light adjustable lens by changing a refraction of the light adjustable lens in a refraction-change zone, thereby causing a wavefront sag, defined as half of a product of the change of the dioptric power and the square of a radius of the refraction-change zone, to be within 10% of its maximum over an ultraviolet spectrum.
B29D 11/00 - Fabrication d'éléments optiques, p. ex. lentilles ou prismes
B29D 11/02 - Yeux artificiels en matériaux plastiques organiques
B29K 683/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du silicium avec ou sans soufre, azote, oxygène ou carbone pour des pièces préformées, p. ex. pour des inserts
In general, the present invention relates to optical elements, which can be modified post-manufacture such that different versions of the element will have different optical properties. In particular, the present invention relates to lenses, such as intraocular lenses, which can be converted into aspheric lenses post-fabrication. Also, the present invention relates to a method for forming aspheric lenses post-fabrication.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Intra-ocular lenses; Intraocular lens biometers; Intraocular lenses; Lenses for surgical implantation; Prosthetic intraocular implants [ Conducting research and clinical trials for others relating to medical devices and pharmaceuticals in the field of ophthalmology ]
81.
Using the light adjustable lens (LAL) to increase the depth of focus by inducing targeted amounts of asphericity
In general, the present invention relates to optical elements, which can be modified post-manufacture such that different versions of the element will have different optical properties. In particular, the present invention relates to lenses, such as intraocular lenses, which can be converted into aspheric lenses post-fabrication. Also, the present invention relates to a method for forming aspheric lenses post-fabrication.
The invention relates to novel optical elements having improved UV protection. The optical element comprises a light adjustable optical element with a UV absorbent layer applied to at least one surface of the optical element. The invention is particularly useful in light adjustable intraocular lenses.
The invention relates to a multi-lens intraocular lens system having an accommodation material between the lenses. The system comprises an posterior lens attached to the posterior surface of the capsular bag and an anterior lens attached to the anterior surface of the capsular bag. The anterior and posterior lenses have different optical properties providing different degrees and types of correction. An accommodation material is place between the anterior and posterior lenses. The accommodation material may comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
