A method for visible light-mediated chemical modification of a polypeptide or protein based on cysteine includes the following steps: allowing a cysteine residue on a cysteine-containing oligopeptide, polypeptide, or protein to undergo a reaction with an activating reagent to generate a free radical precursor in situ; and subjecting the free radical precursor to desulfurization under photocatalytic condition, and allowing the generated free radical intermediate to undergo an addition reaction with an olefin or an alkyne, such that sulfhydryl removal and carbon-carbon bond construction are achieved to produce a chemical modification product of the polypeptide and protein. The method cleverly avoids the influence on the chiral center, and thus the chirality of the amino acid residue can be retained. The method is conducive to well avoiding the occurrence of side reactions, and thus the efficiency of the entire conversion is very high.
The present invention provides a solid-state electrolyte, a preparation method therefor and a use thereof, and an electrochemical device. The preparation method comprises: performing ion exchange on a molecular sieve -Na in an acidic solution, so that cations in pores of the molecular sieve -Na are exchanged into protons; after washing and drying, evaporating water molecules to form a molecular sieve -H, and combining oxygen in an aluminum-oxygen tetrahedron of the molecular sieve -H with the protons to form OH; exchanging OH in the molecular sieve -H into halogen X1 (X1=F, Cl, Br, or I) by means of a halogenation reaction, so as to obtain a molecular sieve -X1; and calcining the molecular sieve -X1 and molten AX2 to obtain the solid-state electrolyte, the pH of the acidic solution being greater than 1.2 and less than 2.1, AX2 comprising an alkali metal halide and/or an alkali metal chalcogenide, and the calcination temperature ranging from 300°C to 500°C. The solid-state electrolyte has high ionic conductivity, and can be independently used as a solid-state electrolyte.
C01B 39/00 - Composés ayant des propriétés de tamis moléculaires et d'échangeurs de base, p. ex. zéolites cristallinesLeur préparationPost-traitement, p. ex. échange d'ions ou extraction de l'aluminium
3.
BATTERY ENERGY STORAGE PARALLEL EQUALIZATION CONVERTER TOPOLOGY AND CONTROL METHOD THEREFOR
The present invention provides a battery energy storage parallel equalization converter topology and a control method therefor. The battery energy storage parallel equalization converter topology comprises a series-connected battery energy storage parallel equalization converter, a main converter, and a plurality of groups of filter inductors; in the main converter, the input side of a DC/DC or DC/AC converter is connected in parallel to a parallel voltage-stabilizing capacitor, and the output side of the DC/AC or DC/AC converter is correspondingly connected to an AC or DC source load; the series-connected battery energy storage parallel equalization converter comprises a plurality of groups of small-capacity DC/DC converters and a common DC bus capacitor; the output sides of all the small-capacity DC/DC converters are connected in parallel by means of the common DC bus capacitor to form a common DC bus; the input side of one group of small-capacity DC/DC converters is connected in series to the input side of the main converter, and the input sides of other groups of small-capacity DC/DC converters are connected in series to a battery pack by means of the filter inductors, respectively. According to the present invention, in a battery charging and discharging process, only a small amount of power flows through the converter, reducing the capacity requirements of the converter, and reducing the transmission efficiency.
H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
H02J 7/34 - Fonctionnement en parallèle, dans des réseaux, de batteries avec d'autres sources à courant continu, p. ex. batterie tampon
H02M 3/158 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation comprenant plusieurs dispositifs à semi-conducteurs comme dispositifs de commande finale pour une charge unique
H02M 7/483 - Convertisseurs munis de sorties pouvant chacune avoir plus de deux niveaux de tension
H02M 1/12 - Dispositions de réduction des harmoniques d'une entrée ou d'une sortie en courant alternatif
4.
TRANSFORMERLESS UNIFIED POWER QUALITY CONDITIONER AND MODULATION METHOD AND CONTROL METHOD THEREFOR
Provided in the present invention is a transformerless unified power quality conditioner, comprising a three-phase conditioner substructure, wherein each phase of the conditioner substructure can comprise an ANPC three-level converter and an output half-bridge module connected to the ANPC three-level converter. Also provided are a corresponding modulation method and system and a corresponding control method and system. Compared with existing voltage regulation apparatuses, the transformerless unified power quality conditioner and the modulation method and control method therefor provided in the present invention do not include a power-frequency transformer in the topology, but use a three-level converter to expand ports to realize voltage regulation, thus having the advantages of lower costs, smaller size, smaller footprint, lower loss, etc.
H02J 3/12 - Circuits pour réseaux principaux ou de distribution, à courant alternatif pour règler la tension dans des réseaux à courant alternatif par changement d'une caractéristique de la charge du réseau
H02M 7/5387 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs, p. ex. onduleurs à impulsions à un seul commutateur dans une configuration en pont
5.
ACTIVITY-REGULATABLE IL-12 FUSION PROTEIN AND USE THEREOF
Provided are an activity-regulatable IL-12 fusion protein and the use thereof. The fusion protein comprises a first structural unit, a second structural unit, and a third structural unit. The first structural unit is selected from a first Fc fragment, or a first antibody or an antigen-binding fragment thereof, wherein the first antibody or the antigen-binding fragment thereof has the binding activity to a tumor antigen or an immune checkpoint; the second structural unit is selected from a cleavable linker or a non-cleavable linker; and the third structural unit comprises an IL-12 cytokine or a functional fragment thereof. The second structural unit mediates the steric hindrance of the first structural unit to mask the activity of the IL-12 cytokine in the third structural unit, thereby reducing the toxic side effects of in-vivo use of the IL-12 cytokine. Compared with a wild-type IL-12, the fusion protein has the advantage of high safety, and can be further fused with an antibody Fab, scFv or VHH, an antigen-binding peptide or a recombinant protein, a polypeptide, etc. to obtain a multifunctional fusion protein that can be conditionally released and activated.
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
The present invention relates to the technical field of image processing, and in particular to an image registration method and apparatus, and an electronic device. The method comprises: acquiring a two-dimensional blood vessel centerline image and a three-dimensional blood vessel centerline image comprising a blood vessel segment of interest; performing feature point extraction on the two-dimensional blood vessel centerline image to obtain a first feature point image; projecting the three-dimensional blood vessel centerline image to a two-dimensional plane, and performing feature point extraction on the obtained two-dimensional projection image to obtain a second feature point image; and inputting the first feature point image and the second feature point image into a pre-trained depth map neural network model for feature point matching to obtain a feature point matching result. The method of the present invention can improve the matching accuracy, the matching speed and the matching density of blood vessel feature points, thereby improving the speed and accuracy of projection parameter optimization and non-rigid registration.
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
A subject analysis method and apparatus, a computer device, and a storage medium. The subject analysis method comprises: acquiring an image to be analyzed corresponding to a target subject and a trained multi-modal dialogue language model; on the basis of a trained visual structure, performing feature extraction on said image to obtain an image feature corresponding to said image; on the basis of a trained attention structure, performing data processing on the image feature to obtain an initial diagnosis result corresponding to the target subject; and on the basis of a trained language structure, performing data processing on the initial diagnosis result to obtain a subject analysis result corresponding to the target subject.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
8.
Testing method for carrier mobility of insulating polymers
A testing method for carrier mobility of insulating polymers is provided, which is based on a testing device for carrier mobility of insulating polymers, including a first box; a second box, disposed inside the first box, provided with a partition plate, and defining a first space and a second space through the partition plate; a sample frame, configured to fix a sample, and disposed in the first space; an X-ray source, disposed in the second space, and configured to generate and emit X-rays to irradiate the sample, to excite generation of carriers in the sample; a voltage generation component, in line connection with the sample, to apply a triangular wave voltage to two ends of the sample, to thereby make the carriers generated in the sample move; and a current detection component, connected to the sample, to thereby collect current signals of the sample generated by movement of the carriers.
H05G 1/12 - Dispositions de l'alimentation en énergie pour alimenter le tube radiogène à rayons X avec du courant continu ou du courant alternatif redressé
Provided is a self-adaptive multi-mode device for high-efficiency and all-weather water harvesting from air. Electromagnetic three-way valves and a four-way reversing valve are controlled by a PLC module integrated with energy efficiency algorithms, thus realizing a device for water harvesting from air capable of self-adaptively switching working modes according to the working environment. By controlling the four-way reversing valve, heat energy and cold energy released by the condenser and the evaporator during the heat pump cycle can be fully utilized, and sorbent coatings at the cooling side are always kept in a sorption state, and sorbent coatings at the heat release side are always kept in a desorption state, so that continuous and high-efficiency water supply is realized, presenting higher energy conversion and utilization efficiency than the conventional electrical heating or electrical refrigeration technology.
The disclosure provides a method for improving the efficiency of a micro-inverter, and a dual-active-bridge-type micro-inverter. The method including: performing power modulation mode switching of a dual-active-bridge-type micro-inverter, such that the power is bi-directionally transmitted from a direct-current side to an alternating-current side and from the alternating-current side to the direct-current side, thereby reducing an effective value of a secondary side current of a transformer; and according to the modulation mode switching characteristic of the dual-active-bridge-type micro-inverter within a power frequency period, performing hybrid optimization on the turn ratio of a primary side to a secondary side and a transformer leakage inductance of a high-frequency transformer of the dual-active-bridge-type micro-inverter.
H02M 7/797 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant continuTransformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif avec possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
11.
ENGINEERED YEAST FOR EFFICIENT AND RAPID SYNTHESIS OF ERYTHRITOL AND CONSTRUCTION METHOD THEREOF
Disclosed are an engineered yeast for efficient and rapid synthesis of erythritol and a construction method thereof. Yarrowia lipolytica is used as a synthetic chassis for genetic improvement. A method for synthesizing erythritol is as follows: using glucose as a carbon source, and a nitrogen source and an inorganic salt as raw materials, sterilizing a medium, cooling the sterilized medium before inoculating yeast Yarrowia lipolytica, performing continuous fermentation or fed-batch fermentation under the condition of oxygen supply, and purifying erythritol from a fermentation broth. Under the condition of continuous feeding, the yield of erythritol is more than 350 g/L, and the production efficiency is more than 4.5 g/L·h, nearly 100% higher than that of a comparative strain.
A mechanism for processing video data is disclosed. The mechanism includes determining whether all Multiplane image (MPI) layers are parallel based on an indication in an MPI information (MPII) supplemental enhancement information (SEI) message. A conversion is performed between a visual media data and a bitstream based on the MPII SEI message.
H04N 19/436 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques caractérisés par les détails de mise en œuvre ou le matériel spécialement adapté à la compression ou à la décompression vidéo, p. ex. la mise en œuvre de logiciels spécialisés utilisant des dispositions de calcul parallélisées
13.
Device and Method for Improving Methane Production in Anaerobic Digestion Through Magnetic Field of Current-Carrying Coil
A device for improving methane production in anaerobic digestion through a magnetic field of a current-carrying coil is provided, which relates to the field of microbial anaerobic digestion. The device includes a feed system, a digester, a stirring system, a magnetic field generation system, a magnetic field measurement system, and a gas flow measurement system. A method for improving methane production in anaerobic digestion through a magnetic field of a current-carrying coil is further provided, including the steps of collecting and pretreating digestion feedstock, collecting and pretreating anaerobic digestion inoculum, manufacturing a current-carrying coil-assisted anaerobic digestion system, starting an anaerobic digestion experiment, and confirming experiment results. A magnetic field is generated by evenly winding a current-carrying coil around a digester, which can provide faster electron transfer for methane anabolic reaction, promote methane anabolic process, and improve the methane yield and efficiency.
C12M 1/107 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens pour recueillir les gaz de fermentation, p. ex. le méthane
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 1/06 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'introduction de gaz avec agitateur, p. ex. avec agitateur à turbine
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
14.
SMART NETWORK INTERFACE CONTROLLER UNLOADING-BASED REMOTE MEMORY SYSTEM
The present invention relates to the technical field of communications. Disclosed is a smart network interface controller unloading-based remote memory system, comprising a computing node, a smart network interface controller and a memory node. The computing node sends a remote memory access request to the smart network interface controller; the smart network interface controller is used for analyzing the remote memory access request and accessing the memory node; the memory node is used for initializing and storing a remote memory. The smart network interface controller comprises a remote memory request processing module, a data address management module and an RDMA communication frontend; the memory node comprises an RDMA communication backend; the use stage of the remote memory system comprises an initialization stage, an application registration stage and an operation stage. The present invention unloads the management unit overhead originally on the memory node to the smart network interface controller, thus achieving in-network management of the remote memory; in addition, the memory node is only responsible for providing the memory, and is completely unaware of remote memory access by applications, thereby effectively reducing the computational management overhead of a CPU on the memory node.
G06F 15/173 - Communication entre processeurs utilisant un réseau d'interconnexion, p. ex. matriciel, de réarrangement, pyramidal, en étoile ou ramifié
15.
BATTERY, GAS SENSING MATERIAL AND PREPARATION METHOD THEREFOR, SENSOR, AND ELECTRIC DEVICE
A battery (100), a gas sensing material and a preparation method for a gas sensing material, a sensor, and an electric device. The battery (100) comprises a gas sensor, which comprises a gas sensing material, wherein the gas sensing material comprises a palladium metal nanosheet having a two-dimensional nanostructure. Gas sensing is implemented by means of a change in surface resistance of the gas sensing material when a palladium metal interacts with a target gas, and no oxygen is involved in the reaction process. By means of the gas sensing material, detection for a target gas can be implemented in an anaerobic or hypoxic condition, and detection for gas generation inside the battery (100) can be implemented, such that the sensitivity and accuracy of gas responses can be effectively improved.
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
16.
DEVICE FOR TESTING GAS TIGHTNESS OF CRYOGENIC THERMAL INSULATION MODULE AND GAS FLUIDITY THEREIN
A device for testing gas tightness of a cryogenic thermal insulation module and gas fluidity therein includes a gas/liquid inlet module, a gas/liquid discharge module and a thermal insulation module. The gas/liquid inlet module includes an inner-space liquid nitrogen inlet valve, an outer-space liquid nitrogen inlet valve, a low-pressure pressure control module, an inner-space high-pressure pressure control module, an outer-space high-pressure pressure control module, a buffer tank, a pressure relief valve and a filter, which are connected by a pipe. The gas/liquid discharge module includes a liquid/gaseous nitrogen discharge valve, an inner-space vent valve and an outer-space vent valve, which are connected by a pipe. An outlet of the gas/liquid inlet module is connected to an inlet of the thermal insulation module, and inlet of the gas/liquid discharge module is connected to an outlet of the thermal insulation module. The present invention can be used to inspect and investigate the tightness of a thermal insulation module under cryogenic and ambient conditions and to test and investigate gas fluidity therein.
G01M 3/32 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par mesure du taux de perte ou de gain d'un fluide, p. ex. avec des dispositifs réagissant à la pression, avec des indicateurs de débit pour récipients, p. ex. radiateurs
A SmartNIC offloading based remote memory system pertains to the field of communication technology and includes a compute node, a SmartNIC and a memory node. The compute node sends a remote memory access request to the SmartNIC. The SmartNIC is used to parse the remote memory access request and access the memory node. The memory node initializes and saves remote memory. The SmartNIC includes a remote memory access request handling module, a data address management module and an RDMA communication front end, and the memory node includes an RDMA communication back end. Use of the remote memory system includes an initialization stage, an application registration stage and a running stage. The system offloads management overhead from the memory node to the SmartNIC, achieving in-network management of remote memory.
H04L 67/1097 - Protocoles dans lesquels une application est distribuée parmi les nœuds du réseau pour le stockage distribué de données dans des réseaux, p. ex. dispositions de transport pour le système de fichiers réseau [NFS], réseaux de stockage [SAN] ou stockage en réseau [NAS]
18.
DEVICE FOR TESTING GAS TIGHTNESS AND INTERNAL GAS FLOW PERFORMANCE OF LOW-TEMPERATURE HEAT INSULATION MODULE
A device for testing gas tightness and internal gas flow performance of a low-temperature heat insulation module, comprising a gas inlet/liquid inlet module (200), a gas discharging/liquid discharging module (100), and a heat insulation module (1). The gas inlet/liquid inlet module (200) comprises an inner-layer space liquid nitrogen inlet valve (6), an outer-layer space liquid nitrogen inlet valve (13), a low-pressure pressure control module, an inner-layer space high-pressure pressure control module, an outer-layer space high-pressure pressure control module, a buffer tank (34), a pressure reducing valve (14), and a filter (35) which are connected by means of pipes. The gas discharging/liquid discharging module (100) comprises a liquid nitrogen/nitrogen gas discharging valve (3), an inner-layer space gas discharging valve (4), and an outer-layer space gas discharging valve (5) which are connected by means of pipes. An outlet of the gas inlet/liquid inlet module (200) is connected to an inlet of the heat insulation module (1), and an inlet of the gas discharging/liquid discharging module (100) is connected to an outlet of the heat insulation module (1). The device can achieve tightness inspection and adaptability research and testing and research of internal space gas flow performance of the heat insulation module (1) under a low-temperature working condition and a normal-temperature working condition.
G01M 3/06 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite par observation de bulles dans un bassin empli de liquide
19.
SUBJECT ANALYSIS METHOD AND APPARATUS, AND COMPUTER DEVICE AND STORAGE MEDIUM
A subject analysis method and apparatus, and a computer device, a storage medium and a computer program product. The subject analysis method comprises: acquiring a target image sequence, clinical data and an image processing model, wherein the target image sequence is obtained by means of performing image sequence conversion on an image to be subjected to detection, and the image processing model includes a pre-trained feature extractor and a trained classification sub-model; performing feature extraction on the target image sequence by means of the feature extractor, and performing analysis processing on a feature extraction result by means of the classification sub-model, so as to obtain a target analysis result; and on the basis of a large-scale language analysis model, performing subject analysis on the target analysis result and the clinical data, so as to obtain a subject analysis result.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
20.
CORE FUEL ELEMENT AND HEAT PIPE COOLED REACTOR HAVING RADIAL EXTRACTION HEAT PIPES
A core fuel element (10) and a heat pipe cooled reactor having radial extraction heat pipes (2). The core fuel element (10) is used for forming a core fuel (1), and the core fuel (1) is used for forming a heat pipe cooled reactor; the core fuel element (10) is divided into a core fuel element segments (11) along the axis; an axial heat pipe channel is formed in each core fuel element segment (11); and a radial heat pipe extraction channel is further formed in the radial direction in each core fuel element segment (11) other than the core fuel element segments (11) located at the head and the tail. The heat pipes (2) are accommodated in both the axial heat pipe channel and the radial heat pipe extraction channel. Straight heat pipes (21) and bent heat pipes (22) are arranged in cooperation with the axial heat pipe channels and the radial heat pipe extraction channels, so that a plurality of heat pipes (2) are arranged in each axial heat pipe channel in the core fuel element (10), and thus the heat exchange effect of a single core fuel element (10) is improved, thereby improving the overall heat exchange efficiency of the heat pipe cooled reactor.
G21C 15/14 - Aménagement ou disposition de passages dans lesquels la chaleur est transférée au réfrigérant, p. ex. pour la circulation du réfrigérant à travers les supports des éléments combustibles provenant des conduits servant au passage d'un fluide chaudAménagement ou disposition de passages dans lesquels la chaleur est transférée au réfrigérant, p. ex. pour la circulation du réfrigérant à travers les supports des éléments combustibles provenant des conduits comprenant des appareils auxiliaires, p. ex. pompes, caméras
21.
Piston pin hole friction and wear test and torque measurement device
A piston pin hole friction and wear test and torque measurement device in power machinery field, comprising a driving system, a torque measurement system, a loading system, a temperature control system, an oil supply system and a central controller. The driving system simulates the oscillation of the connecting rod. The loading system simulates the time-varying cylinder pressure load. The oil supply system and the oil channels of the connecting rod, bushing, and piston pin simulate the oil supply state. The torque measurement system comprises a total friction torque measurement device and a small head bushing hole friction torque measurement device, and measures the friction torque at the piston pin seat hole and the piston pin small head hole in real time. The temperature control system simulates the thermal load. The present application carries out tests based on actual components and realizes real-time measurement of friction torques.
A tracking and adaptive compensation method for power fluctuation of a pulse load of a ship is provided. The method includes: based on a microgrid topology model of the ship, a pulse load model of the pulse load, and an interharmonic power and pulse parameter relationship model, performing power fluctuation tracking, frequency selection and a power spectrum analysis to obtain filtering parameters of a low-pass filter and filtering parameters of a band-pass filter; performing waveform adaptation to eliminate a phase delay caused by the low-pass filter and the band-pass filter, and obtaining a control command for a power compensation strategy; and generating, by a power loop, a pulse width modulation (PWM) signal to control a switching tube in a bidirectional direct current (DC)/DC converter of each of an energy storage battery pack and a supercapacitor of a hybrid energy storage system.
A tyrosinase-based transdermal delivery system for treating vitiligo is of a core-shell structure, wherein the core is tyrosinase, and the shell is a polymer shell layer. Double bonds are introduced into tyrosinase, and the surface of the protein is coated with a polymer protective layer by means of an in-situ polymerization reaction, so that the activity of tyrosinase can be effectively protected, and transdermal delivery of tyrosinase can be promoted. Moreover, by means of regulating polymerization conditions of the polymer shell, the targeted delivery of a tyrosinase nanogel to the melanocytes deep in the skin and hair follicles can be controlled, so that the in-situ synthesis of melanin is promoted. The transdermal delivery system can also load an active small molecule with an anti-inflammatory function in the center of tyrosinase, and the small molecule is released after being delivered along with the tyrosinase nanogel to an inflammatory region of vitiligo in a targeted manner, so that inflammation is relieved, and melanocytes are protected from damage.
Provided are a miniature bacterium capable of improving formaldehyde tolerance and monocarbon compound utilization capacity, and construction. A minicell not containing genomic DNA is obtained by regulating a bacterial cell division system, and the regulating the bacterial cell division system is implemented by overexpressing a cell division protein ftsZ and homologs thereof and/or inhibiting a Z-ring positioning system minCDE and homologs thereof. Genomic DNA damage caused by formaldehyde is effectively relieved, thus improving the tolerance of bacteria to formaldehyde, and on this basis, improving the utilization capacity of monocarbon compounds in all methylotrophic bacteria that use formaldehyde as a metabolic intermediate.
A protein carrier-based active ingredient transdermal delivery system, which is a small molecule active ingredient-protein-polymer composite structure and comprises a small molecule active ingredient, a protein loaded with the small molecule active ingredient, and a polymer coating a surface of the protein. The protein is modified with a polymerizable double-bond compound. After the loading of the small molecule active ingredient, a polymerization reaction is initiated on the surface of the protein in situ, so that the surface of the protein is coated with a polymer layer. The polymer layer is biologically friendly, and the surface properties of the polymer layer can be regulated and controlled according to the transdermal depth requirement, thereby achieving the targeted transdermal delivery of proteins and active small molecules while breaking through the skin barrier, and significantly overcoming the defect of poor delivery efficiency of previous protein-based delivery systems. The transdermal delivery system has a simple preparation method with a high yield, and thus can be industrially produced on a large scale.
A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
26.
ASYMMETRIC BINOCULAR ENDOSCOPE AND THREE-DIMENSIONAL RECONSTRUCTION METHOD THEREFOR
SHANDONG WEIGAO HONGRUI MEDICAL TECHNOLOGY CO., LTD. (Chine)
SHANGHAI JIAO TONG UNIVERSITY (Chine)
Inventeur(s)
Qian, Dahong
Abrégé
The present application relates to the field of endoscopes. Disclosed are an asymmetric binocular endoscope and a three-dimensional reconstruction method therefor, which can ensure an ultra-high definition and also solve the problem of a spatial arrangement being insufficient when a binocular camera module is used in an endoscope. The method comprises: a first camera module performing white-light imaging, and a second camera module performing fluorescence imaging, wherein the diameter of the first camera module is greater than the diameter of the second camera module, and the resolution of the first camera module is greater than the resolution of the second camera module; processing an image collected by means of the first camera module, such that the resolution of an image obtained by processing the image collected by means of the first camera module is consistent with the resolution of an image collected by means of the second camera module; on the basis of the image obtained by processing the image collected by means of the first camera module and the image collected by means of the second camera module, performing registration and three-dimensional reconstruction to obtain a three-dimensional image; overlaying the three-dimensional image with, as texture, the image collected by means of the first camera module; and Superimposing, onto the texture, the image collected by means of the second camera module, so as to obtain a fluorescence three-dimensional image.
This invention discloses a wave field reconstruction method via optical perception, including: (1) building a data platform for a virtual wave field; (2) pre-training a domain converter module using color image data of the virtual wave field and real water surface image data captured by a camera; (3) pre-training a depth estimation module using generated paired color image data and depth image data of the virtual wave field; (4) converting the style of a real water surface image into a virtual-water-surface-style image via the domain converter module; (5) outputting the virtual-water-surface-style image as a depth image with the same style and recording the distance between a wave surface sampling point and the camera's optical center; and (6) generating surface point cloud data of a water surface wave field with the camera's optical center as the coordinate origin. The method enables real-time, robust wave field depth reconstruction, ensuring reliability and authenticity.
A hybrid modulation method and system is provided. The method includes the following steps: establishing a simulation model of a spatial light modulator; obtaining, by the simulation model, a phase modulation depth of a phase modulation performed by a blazed grating at each communication port, where within a phase modulation range, when light output from a zeroth communication port is diffracted into a kth target communication port, the simulation model obtains diffraction efficiencies of various orders at different phase modulation depths, a phase modulation depth Akπ corresponding to a highest isolation is selected as a phase modulation depth of the kth communication port, where k∈(0, K); and performing a phase modulation depth Akπ on light that is output from the zeroth communication port of a communication fiber and that is to be diffracted into the kth target communication port.
G02B 27/00 - Systèmes ou appareils optiques non prévus dans aucun des groupes ,
G02B 6/293 - Moyens de couplage optique ayant des bus de données, c.-à-d. plusieurs guides d'ondes interconnectés et assurant un système bidirectionnel par nature en mélangeant et divisant les signaux avec des moyens de sélection de la longueur d'onde
A state prediction method and apparatus, a computer device, a storage medium, and a computer program product. The method comprises: obtaining data for detection, wherein the data for detection comprises a fundus image and covariate data, and the covariate data is variable data for assisting in identifying a target lesion; on the basis of a preset feature extraction model, performing feature extraction on the fundus image and the covariate data respectively to obtain an image feature vector, a first weight corresponding to the image feature vector, a covariate feature vector, and a second weight corresponding to the covariate feature vector; and processing the image feature vector and the covariate feature vector on the basis of the first weight, the second weight, and a preset hybrid model to obtain a target state prediction result, wherein the preset hybrid model is constructed on the basis of the image feature vector and the covariate feature vector that separately satisfy a maximum likelihood function condition and under the conditions where the data for detection has censored data or does not have censored data.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
A turbine blade with a bifurcated cooling duct and a tandem cooling duct. The turbine blade comprises a turbine cooling blade (1), and the turbine cooling blade (1) comprises an outer wall (10), an inner cavity, an inner wall (11), a spanwisely arranged multi-stage bifurcated cooling duct (12), a chordwisely arranged multi-stage bifurcated cooling duct (13), and a tandem cooling duct (14), wherein the inner cavity is arranged in the outer wall (10); the inner wall (11) is arranged in the inner cavity; the spanwisely arranged multi-stage bifurcated cooling duct (12) is connected to the outer wall (10), and the spanwisely arranged multi-stage bifurcated cooling duct (12), the chordwisely arranged multi-stage bifurcated cooling duct (13) and the tandem cooling tube (14) are connected to the inner wall (11) and the outer wall (10); and the spanwisely arranged multi-stage bifurcated cooling duct (12), the chordwisely arranged multi-stage bifurcated cooling duct (13) and the tandem cooling duct (14) are arranged on the turbine cooling blade (1). By means of using a structure of the spanwisely arranged multi-stage bifurcated cooling duct, the chordwisely arranged multi-stage bifurcated cooling duct and the tandem cooling duct, the structure can increase the contact area between a cooling fluid and the cooling ducts, and can allow for more adequate heat exchange between the cooling fluid and the blade, thereby increasing the cooling efficiency.
Disclosed in the present invention are a gallium-based alloy, a preparation method therefor and a use thereof. The preparation method comprises: mixing and grinding metal gallium and one or more of metals other than the metal gallium to form an alloy, and then carrying out annealing treatment at a temperature of 30-400°C. When being used for preparing a negative electrode and being further applied to a battery, the gallium-based alloy prepared by the method can suppress the continuous growth of negative electrode dendrites in the battery, so that uniform deposition of ions is realized, the contact area of an electrode and an electrolyte is increased, the critical current density is improved, and the heat dissipation of the battery is accelerated, and thus the safety is improved, thereby improving the cycle performance of the battery. The problem of short cycle life of the metal secondary battery is effectively solved. Moreover, the method is simple and effective, and has simple and convenient process, high efficiency, and mild conditions.
C22C 28/00 - Alliages à base d'un métal non mentionné dans les groupes
C22F 1/16 - Modification de la structure physique des métaux ou alliages non ferreux par traitement thermique ou par travail à chaud ou à froid des autres métaux ou de leurs alliages
C22C 1/04 - Fabrication des alliages non ferreux par métallurgie des poudres
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
H01M 10/613 - Refroidissement ou maintien du froid
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
32.
ALUMINUM ALLOY MATERIAL, ALUMINUM ALLOY STRUCTURAL PART AND PREPARATION METHOD THEREFOR, BATTERY BOX BODY, BATTERY SYSTEM, ELECTRIC DEVICE AND USE
A gravity-type variable-length seabed single point mooring connection apparatus for a floating wind turbine. The apparatus comprises: a floating body, carrying at least two pulley fairleads; a single point anchor, disposed on the seabed and to which a rotatable apparatus is connected; and at least one weight, located in the water below the floating body. The weight and the single point anchor are connected by means of a mooring cable passing through the pulley fairleads. The prevent invention has small seabed coverage area, is environmentally friendly, has high efficiency for a mooring system, and implements a wind vane function, and is safe, reliable, practical, and feasible. The present invention can be used in offshore mooring positioning of floating wind power platforms having a water depth of 50 meters to 300 meters or even more than 1500 meters.
The present application relates to the technical field of medicine, and provides a use of PTPRT as a biomarker and a target for predicting the efficacy of immune checkpoint therapy in lung cancer. Further provided is a use of the expression quantity of PTPRT in the prediction or evaluation of the efficacy of immune checkpoint therapy in cancer. Experiments show that the low expression of PTPRT, as a marker for predicting the efficacy of immune checkpoint therapy in lung cancer, can accurately predict progression-free survival (PFS) of lung cancer patients. Inhibition of PTPRT can increase the proportion of tumor-infiltrating CD8+T cells and synergize with immune checkpoint therapy to enhance the anti-tumor effect of an immune checkpoint inhibitor.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
35.
BATTERY, GAS SENSING MATERIAL AND PREPARATION METHOD THEREFOR, SENSOR, AND ELECTRICAL DEVICE
A battery, a gas sensing material and a preparation method therefor, a sensor, and an electrical device. The battery (100) comprises a gas sensor; the gas sensor comprises a gas sensing material; the gas sensing material comprises a palladium-carbon nanotube composite material; a response gas of the palladium-carbon nanotube composite material under an oxygen-free condition comprises at least one of hydrogen, carbon monoxide and ammonia. The battery can achieve high-sensitivity response and rapid recovery of a target gas in an oxygen-free environment, so that the safety performance of the battery is improved.
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
36.
CONSTRUCTION METHOD FOR CORROSION-RESISTANCE DEGREE-MECHANICAL PROPERTY ANALYSIS MODEL OF METAL MATERIAL, AND USE THEREOF
The present application relates to a construction method for a corrosion-resistance degree-mechanical property analysis model of a metal material, and the use thereof. The construction method for the analysis model comprises the following steps: using a metal material as a test object, and acquiring corrosion test experimental data sets at different equivalent corrosion time points under corrosion test conditions and mechanical property test experimental data sets at different corrosion degrees corresponding to the different equivalent corrosion time points; and respectively establishing an empirical relational expression of corrosion parameters changing with an equivalent corrosion time and an empirical relational expression of mechanical parameters changing with the equivalent corrosion time.
G16C 60/00 - Science informatique des matériaux, c.-à-d. TIC spécialement adaptées à la recherche des propriétés physiques ou chimiques de matériaux ou de phénomènes associés à leur conception, synthèse, traitement, caractérisation ou utilisation
G16C 20/70 - Apprentissage automatique, exploration de données ou chimiométrie
37.
BATTERY, GAS SENSING MATERIAL AND PREPARATION METHOD THEREFOR, SENSOR, AND ELECTRIC DEVICE
The present application discloses a gas sensing material and a preparation method therefor, a sensor, a battery, and an electric device. The gas sensing material is a metal organic framework (MOF) having a one-dimensional nanostructure, and a gas response mechanism of the gas sensing material is transfer of coordination electrons. By means of the described method, the present application can achieve detection of target gas in an oxygen-free environment, and can achieve detection of gas generated in the battery. Furthermore, the gas detection sensitivity and selectivity can be improved, the gas response time can be shortened, and the gas detection limit can be lowered.
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
H01M 10/48 - Accumulateurs combinés à des dispositions pour mesurer, tester ou indiquer l'état des éléments, p. ex. le niveau ou la densité de l'électrolyte
Disclosed in the present application are a battery, a gas sensing material and a preparation method therefor, a sensor and an electric device. The battery comprises a gas sensor, which comprises a gas sensing material, wherein the gas sensing material comprises an M/MXene composite material, the M/MXene composite material comprising a metal (M) monoatom and an MXene material, and/or comprising a metal (M) cluster and an MXene material. The gas sensing material provided by the present application can achieve the detection of a target gas in an oxygen-free or low-oxygen environment and the detection of gas production within a battery. Furthermore, the sensitivity and selectivity of gas detection can be improved, the response and recovery speeds can be increased, and the detection limit of a gas can be reduced.
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
39.
ALUMINUM ALLOY MATERIAL, ALUMINUM ALLOY STRUCTURAL PART, BATTERY CASE, BATTERY SYSTEM, ELECTRIC DEVICE, PREPARATION METHOD AND USE
An aluminum alloy material, an aluminum alloy structural part, a battery case, a battery system, an electric device (6), a preparation method and a use. The aluminum alloy material comprises the following composition elements: Si, Mn, Mo, Zr, Sr, Sc, B, a matrix element Al and inevitable impurity elements, and in the aluminum alloy material, both the content of the element Mo and the content of the element Zr are low.
B21C 37/00 - Fabrication de tôles, barres, fils, tubes ou profilés métalliques ou de produits semi-finis similaires, non prévue ailleursFabrication de tubes de forme particulière
40.
FUSED QUINONOXIME IMIDAZOLE, ONIUM DERIVATIVES THEREOF, PREPARATION AND USE THEREOF
A fused quinonoxime imidazole, an onium derivative thereof, preparation and use thereof are provided; the fused quinonoxime imidazole and an onium derivative thereof having structures represented by the following Formulas (I), (II), (III) and (IV).
A fused quinonoxime imidazole, an onium derivative thereof, preparation and use thereof are provided; the fused quinonoxime imidazole and an onium derivative thereof having structures represented by the following Formulas (I), (II), (III) and (IV).
A fused quinonoxime imidazole, an onium derivative thereof, preparation and use thereof are provided; the fused quinonoxime imidazole and an onium derivative thereof having structures represented by the following Formulas (I), (II), (III) and (IV).
The fused quinonoxime imidazole has a novel structure, where the substituted quinone imidazole and the onium derivative thereof are fused with an aromatic carbon ring or a heterocyclic ring, and are characterized by oximation substitution. The derivative shows good inhibition activity against tumor cell growth, exhibits excellent selectivity, and has a good antitumor application prospect through in vitro and in vivo tests. Moreover, the antiviral and antibacterial effects thereof are also very good.
C07D 235/02 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, condensés avec d'autres cycles condensés avec des carbocycles ou avec des systèmes carbocycliques
A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
A61K 31/497 - Pyrazines non condensées contenant d'autres hétérocycles
C07D 403/06 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée ne contenant que des atomes de carbone aliphatiques
C07D 405/04 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 405/06 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 409/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 409/06 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
41.
FLEXIBLE DC CONVERTER FEATURING MULTI-PORT DC POWER FLOW CONTROL AND CONTROL METHOD THEREOF
A flexible DC converter comprises a MMC and a DCPFC embedded within the flexible DC converter. The flexible DC converter features modularity and a flexible number of ports, enabling bidirectional control of DC power flow of two or more lines, addressing the issue of insufficient degrees of freedom in DC power flow control in meshed DC systems. The DCPFC is directly embedded in the flexible DC converter, allowing for energy balance without the need for external power sources and high-voltage isolation devices, with a wide range of power flow regulation. The control method can manage both internal and external energy balance of the device. Additionally, a main circuit parameter designing method can serve as a basis for selecting circuit components for the device. A fault protection strategy and an active fault current suppression method can enhance the reliability of the device under complex extreme conditions.
H02J 3/36 - Dispositions pour le transfert de puissance électrique entre réseaux à courant alternatif par l'intermédiaire de haute tension à courant continu
H02J 3/00 - Circuits pour réseaux principaux ou de distribution, à courant alternatif
H02J 3/06 - Commande du transfert de puissance entre réseaux connectésCommande du partage de charge entre réseaux connectés
H02J 3/14 - Circuits pour réseaux principaux ou de distribution, à courant alternatif pour règler la tension dans des réseaux à courant alternatif par changement d'une caractéristique de la charge du réseau par interruption, ou mise en circuit, des charges du réseau, p. ex. charge équilibrée progressivement
H02J 3/24 - Dispositions pour empêcher ou réduire les oscillations de puissance dans les réseaux
A power electronic transformer includes three modules, the three modules each including: a first submodule; a second submodule; and a third submodule including a first power conversion module including N first power conversion units having input ports connected to the N output ports of the first submodule in one-to-one correspondence, and a second power conversion module including M first power conversion units having input ports connected to the M output ports of the second submodule in one-to-one correspondence, the first input port of the first submodule of the three modules has one terminal connected to three phases of a first three-phase alternating current in one-to-one correspondence, and the other terminal connected to three phases of a second three-phase alternating current in one-to-one correspondence, output ports of the N first power conversion units are connected in parallel to output ports of the M first power conversion units.
H02M 1/00 - Détails d'appareils pour transformation
H02M 5/458 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant alternatif, p. ex. pour changement de la tension, pour changement de la fréquence, pour changement du nombre de phases avec transformation intermédiaire en courant continu par convertisseurs statiques utilisant des tubes à décharge ou des dispositifs à semi-conducteurs pour transformer le courant continu intermédiaire en courant alternatif utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
H02M 7/219 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant continu sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs dans une configuration en pont
43.
SEALED ENERGY STORAGE DEVICE AND ENERGY STORAGE AND POWER GENERATION INTEGRATED SYSTEM
Provided in the present invention are a sealed energy storage device and an energy storage and power generation integrated system. The sealed energy storage device has an energy storage state and a power generation state, comprising a variable capacity cavity, a connecting pipe, a fluid storage structural body connected to the variable capacity cavity by means of the connecting pipe, a control valve arranged on the connecting pipe, a reversible energy storage unit, and a control unit in signal connection with the control valve, wherein the variable capacity cavity, the connecting pipe and the fluid storage structural body are connected to form a sealed space. By means of transferring a fluid in a sealed system to create a negative pressure space for energy storage, the present invention enables unstable energy to be stored for stable output. Compared with conventional physical energy storage methods, the present invention has advantages such as high environmental adaptability, large energy density, high energy utilization rate, rapid response, flexible application scenarios and high scalability. Particularly, the present invention has a better effect when used underwater, without causing interference to the marine environment, helping protect the marine ecological environment; thus, the degree of environmental friendliness is high.
Provided in the present invention is a micro-bump laser printing method for packaging a three-dimensional integrated circuit. The method comprises: placing, on a chuck below a donor film, a chiplet on which micro-pads have been prepared; and using pulsed laser to irradiate the donor film by means of aligning the pulsed laser with the donor film, such that the donor film is partially molten and generates metal droplets for spraying, and the metal droplets are deposited on surfaces of the micro-pads, and are then cooled and solidified to form a metal micro-bump array. In the present invention, the micro-bumps are prepared by means of laser direct-writing printing without requiring a mask, thereby realizing a simple process flow and a short period; micro-bump arrays having different sizes and position distributions are prepared by means of changing the sizes of laser spots and the position at which the donor film is irradiated, thereby realizing high process flexibility; and micro-bumps having different components are prepared by means of replacing the material of the donor film, thereby realizing a wide material application range.
H01L 21/60 - Fixation des fils de connexion ou d'autres pièces conductrices, devant servir à conduire le courant vers le ou hors du dispositif pendant son fonctionnement
45.
NUCLEAR-THERMAL COUPLING IMPLEMENTATION METHOD BASED ON DEEPM&MNET NEURAL NETWORK
A method for implementing nuclear-thermal coupling based on the DeepM&Mnet neural network is disclosed; the proposed nuclear-thermal coupling implementation method comprises the following steps; first construct DeepM&Mnet neural network inclusive of numerical solvers for the material temperature and neutron physics fields; then the DeepM&Mnet neural network is trained by utilizing physics constraints of the numerical solvers for the material temperature and neutron physics fields; finally, the formation of the network loss function is adjusted based on the training results to achieve nuclear-thermal coupling simulation; according to the method, a numerical solver for material temperature and neutron physics fields, or a deep operator network (DeepONet) is applied for fitting a numerical solution process, and a DeepM&Mnet is constructed on the basis.
G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle
A disinfection product based on citric acid and a natural naphthoquinone compound, and a preparation method thereof are provided. The disinfectant includes, in weight percentage, 15-25% of citric acid, 0.01-0.1% of a natural naphthoquinone compound, a certain amount of ethanol, and a certain amount of deionized water containing an alkali metal salt and an alkaline-earth metal salt. When in use, the disinfectant can be sprayed on the surface of an object or the diluted disinfectant can be used for cleaning an object to be disinfected. The disinfection product features high disinfection and sterilization efficacy, low irritation, and low corrosiveness, and is free from peculiar smell and environmental toxicity in disinfection residues. The disinfectant is suitable for the disinfection of cold chain and the disinfectant of surfaces of vegetable and food.
A01N 37/36 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant au moins un groupe carboxylique ou un thio-analogue, ou d'un de leurs dérivés, et un atome d'oxygène ou de soufre lié par une liaison simple, liés au même squelette carboné, cet atome d'oxygène ou de soufre ne faisant pas partie d'un groupe carboxylique ou d'un thio-analogue, ou d'une de leurs dérivés, p. ex. acides hydroxycarboxyliques
A01N 35/06 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant deux liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. un radical aldéhyde contenant des groupes cétone ou thiocétone faisant partie d'un cycle, p. ex. cyclohexanone, quinoneLeurs dérivés, p. ex. cétals
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
47.
SMG IMPLEMENTATION SYSTEM BASED ON RAW DATA, AND METHOD
An SMG implementation system based on raw data, and a method. The system comprises: a raw data buffer region provided at an input end of a DSP, a data buffer region creation and control module, a DSP control processing module, a multi-modal selection module, and an adaptive multi-modal computing module, wherein the raw data buffer region temporarily stores raw modal data from sensors; the multi-modal selection module determines the importance of modal data in the raw modal data by means of a neural network and then outputs important modal data to a DSP for processing; the data buffer region creation and control module implements create, read and write data buffer regions for an application; the DSP control processing module provides a system call; and the adaptive multi-modal computing module constructs and trains the neural network, and then performs online adaptive modality fusion computing on the basis of input modalities and generates computing results. In the present invention, modality gating processing is performed in advance, so as to screen, in advance, modal data entering a DSP, thereby ensuring that unnecessary modal data does not pass through the DSP, and thus avoiding unnecessary energy and execution time waste caused by the DSP.
Embodiments of the present disclosure provide a data processing method, an electronic device, and a computer-readable storage medium. In a community division scenario, a community division algorithm is performed in parallel, through a plurality of threads and using fine-grained locks implemented based on atomic operation instructions, on a relationship network to realize community division.
A method of optimizing resource allocation based on adaptive multi-faceted cutting of a power dispatching model is provided. The method includes constructing and analyzing a two-stage distributed robust model by using acquired operation state information of a power system and identifying therefrom a second-stage infinite-dimensional decision variable. A model is reconstructed by dimensionality reduction and a dispatching model is solved to obtain a dispatching strategy scheme for realizing optimal resource allocation. The two-stage distributed robust dispatching model is transformed into a finite-dimensional problem, so that rapid solution is realized. By improving the solving efficiency and the accuracy of the power dispatching model, the working efficiency of the power system is obviously improved.
The invention provides a method for conditional regulating gene expression, comprising: introducing a miRNA target sequence into a non-coding region of a target gene in a plant cell, wherein the non-coding region comprises 5'UTR, 3'UTR or an intron region.
Methods and systems for predicting a subject's response to a therapy by obtaining a first plurality of nucleic acid sequences for genomic DNA from a sample from the gut of a subject. Determine, from the nucleic acid sequences, a plurality of genomic abundance values for a plurality of gut bacteria. Apply a model to the plurality of genomic abundance values, thereby obtaining the prediction of a subject's response to a therapy as an output of the model.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
G16B 30/10 - Alignement de séquenceRecherche d’homologie
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16B 20/00 - TIC spécialement adaptées à la génomique ou protéomique fonctionnelle, p. ex. corrélations génotype-phénotype
A surface acoustic wave filter includes a support substrate with a first acoustic velocity layer disposed above. The first acoustic velocity layer is silicon dioxide with a piezoelectric layer above. Euler angles of a cut of the piezoelectric layer are (−5° to 5°, 81° to 83°, 85° to 95°), and an interdigital electrode is disposed above the piezoelectric layer. A second acoustic velocity layer included between the first acoustic velocity layer and the support substrate; and a material of the second acoustic velocity layer is aluminum nitride or silicon nitride, where a longitudinal wave acoustic velocity in the first acoustic velocity layer is lower than a longitudinal wave acoustic velocity in the piezoelectric layer, and a longitudinal wave acoustic velocity in the second acoustic velocity layer is higher than the longitudinal wave acoustic velocity in the piezoelectric layer.
The present invention provides a high-voltage energy storage power system and a battery cluster state precise sensing method thereof. The high-voltage energy storage power system comprises: a battery cluster, a start-up protection circuit, PCS units, a fault bypass circuit, a direct-current side filter inductor, a bus capacitor, PCS unit sub-controllers, and a BMS; direct-current side positive electrodes of the PCS units are sequentially connected in series to the direct-current side start-up protection circuit, the battery cluster, and the direct-current side filter inductor, and then connected to direct-current side negative electrodes of the PCS units; alternating-current side positive electrodes of the PCS units are sequentially connected in series; the bus capacitor is connected in parallel to two electrodes at a direct-current side of each PCS unit; the PCS unit sub-controllers are respectively connected to the fault bypass circuit, the PCS units, the start-up protection circuit, and the BMS; and the BMS is connected to the battery cluster.
An echo planar imaging method capable of reducing image distortion is provided. Two radio frequency (RF) pulses α and β are used to respectively flip over a longitudinal magnetization into a transverse plane at different moments, so as to obtain observable transverse magnetization; the transverse magnetization obtained by flipping over the longitudinal magnetization by means of α and β are respectively rephased in two different echo trains by means of gradient pulses. Navigator echo signals are respectively collected before the two gradient echo trains, and the amplitude difference between two gradient echo train signals is corrected on the basis of the amplitude difference between the two navigator echo signals. Correcting the signals collected by the two gradient echo trains, so as to obtain two pieces of image data, and the two pieces of image data are averaged to obtain a final image.
The present invention provides an asymmetric catalytic hydrogenation method for a compound as shown in formula (I), comprising the following steps: in a hydrogen atmosphere, performing asymmetric hydrogenation reduction on the compound as shown in formula (I) in a solvent in the presence of a catalyst formed by a ligand, an iridium salt and an inorganic salt to form a compound as shown in formula (II), wherein the reaction formula is shown below. The catalyst used in an asymmetric catalytic hydrogenation synthesis method of the present invention is low in cost, the raw materials are completely converted, the ee value of the obtained target product can reach 99%, and thus the asymmetric catalytic hydrogenation synthesis method is suitable for industrial production.
C07C 213/08 - Préparation de composés contenant des groupes amino et hydroxy, amino et hydroxy éthérifiés ou amino et hydroxy estérifiés liés au même squelette carboné par des réactions n'impliquant pas la formation de groupes amino, de groupes hydroxy ou de groupes hydroxy éthérifiés ou estérifiés
C07C 217/84 - Composés contenant des groupes amino et hydroxy éthérifiés liés au même squelette carboné ayant des groupes amino et des groupes hydroxy éthérifiés liés à des atomes de carbone de cycles aromatiques à six chaînons du même squelette carboné ayant des groupes amino et des groupes hydroxy éthérifiés liés à des atomes de carbone de cycles aromatiques à six chaînons non condensés du même cycle aromatique à six chaînons non condensé l'atome d'oxygène d'au moins un des groupes hydroxy éthérifiés étant lié de plus à un atome de carbone acyclique
C07F 15/00 - Composés contenant des éléments des groupes 8, 9, 10 ou 18 du tableau périodique
56.
ENCODING METHOD, DECODING METHOD, CODE STREAM, ENCODER, DECODER, AND STORAGE MEDIUM
GUANGDONG OPPO MOBILE TELECOMMUNICATIONS CORP., LTD. (Chine)
Inventeur(s)
Xu, Yiling
Huang, He
Zeng, Xinyao
Wei, Honglian
Abrégé
Embodiments of the present application disclose an encoding method, a decoding method, a code stream, an encoder, a decoder, and a storage medium. The encoding method comprises: determining a first basic mesh of a current frame on the basis of an original mesh of the current frame; on the basis of a second basic mesh of a reference frame, performing matching point selection on the original mesh of the current frame to obtain a third basic mesh, wherein vertices in the third basic mesh match those in the second basic mesh; determining a target encoding mode of the current frame on the basis of an error measurement difference between the first basic mesh and the third basic mesh; and encoding the current frame on the basis of the target encoding mode. In this way, the encoding efficiency of meshes can be improved while ensuring the quality of mesh reconstruction.
Provided in the present application are a battery state-of-charge balancing method, an apparatus, and an electronic device. The method comprises: when a modular multilevel converter-based energy storage system is disconnected from a power grid, injecting a direct circulating current so as to achieve inter-phase SOC balance; and on the basis of the direction of the direct circulating current and the SOC of each bridge arm in the modular multilevel converter-based energy storage system, changing the direct-current voltage of an upper bridge arm and a lower bridge arm of a same phase. By means of the injected direct circulating current, a direct-current power is generated, so that the power distribution of the upper bridge arm and the lower bridge arm is changed, and further the SOC balance between the upper bridge arm and the lower bridge arm in the same phase is achieved. Thus, the problem of inter-phase and intra-phase SOC balancing when the modular multilevel converter-based energy storage system is disconnected from the power grid is effectively solved.
Provided are a corrosion-resistant oxide dispersion strengthened steel and a method for preparing the corrosion-resistant oxide dispersion strengthened steel. The corrosion-resistant oxide dispersion strengthened steel includes in percentage by mass: Cr at 8.0 wt %-10.0 wt %, Al at 4.0 wt %-6.0 wt %, Ce at 0.2 wt %-0.8 wt %, Y at 0.2 wt %-0.4 wt %, O at 0.05 wt %-0.3 wt %, C less than or equal to 0.0016 wt %, and the balance of Fe.
A device for measuring a diameter error of a roller for threaded pair transmission in the technical field of power machinery, comprising a roller fixing device, a laser measuring device, a screw driving device, and a roller to be measured. The roller fixing device comprises a fixing rod, a supporting structure, guide rails, nut-bolt pairs and a fixing beam, to fix the roller. The laser measuring device comprises pressing columns, laser sensors, laser receiving plates, laser sensor placement plates and moving structures, which ensure the verticality of the roller. The screw driving device comprises ball screw pairs, bearings, nuts, nut connecting bolts and cranks, to drive the moving structures to ensure the distance between the laser measuring device and the roller. The roller diameter error measuring device of the present disclosure is simple to operate, has fewer human influence factors, and has high measurement accuracy.
The present disclosure provides a binary code similarity detection system based on hard sample-aware momentum contrastive learning, comprising: a preprocessing device for transforming the binary code into tokens for neural networks; a feature extracting device for using the tokens to generate final representation embeddings for the binary code; and a similarity detection device for using the representation embeddings to detect the binary code similarity.
RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE (Chine)
Inventeur(s)
Dong, Chen
Sun, Qinli
Ni, Ling
Abrégé
Disclosed in the present invention is a T cell, wherein the expression of a given protein in the T cell is changed, and the given protein is suitable for regulating the expression of BCL6 in the T cell. The T cell is at least one of a CD8+T cell and a CD4+T cell, preferably a CD8+T cell specifically recognizing tumor cells. The given protein is suitable for regulating the expression of BCL6 by means of the IL-2-STAT5 pathway and/or TGF-beta-SMAD2 pathway. The expression of BCL6 in the T cell is up-regulated. The expression of the given protein in the T cell is changed. The given protein comprises at least one downstream protein on the IL-2-STAT5 pathway, and the expression of the given protein is down-regulated. The given protein comprises at least one selected from PRDM1 or a member of the same family thereof.
The present application relates to the technical field of machine learning. Disclosed are a method and system for interpreting common interaction utility amongst multiple blackbox artificial intelligence models. The method and the system can automatically analyze a common interaction modeled by multiple different artificial intelligence models, and can also analyze a common interaction modeled by the same model having an input subjected to different perturbations. Implementing the method and system comprises the following steps: providing an input sample; using multiple blackbox models to predict the same data, or using one blackbox model to predict different data so as to obtain a plurality of prediction results; on the basis of the plurality of prediction results, modeling interaction effects between input units of the sample, calculating interaction strengths of combinations formed by the input units, and expressing an output of each model as "AND interaction utility" and "OR interaction utility" between the combinations of the input units; and learning the common "AND interaction utility" and "OR interaction utility" shared amongst the different artificial intelligence models.
The application relates to an energy storage system, a filter parameter acquisition method and apparatus, and an electronic device, and relates to the field of power systems. The method comprises: acquiring relevant parameters of an energy storage system, the relevant parameters comprising: the working frequency of a power grid connected to the energy storage system, the current amplitude of the power grid, the modulation ratio of the power grid, the voltage of sub-modules in the energy storage system, the current pulsation rate, and the voltage pulsation rate; and, on the basis of the relevant parameters and the corresponding relationship between filter parameters in the sub-modules and the relevant parameters, determining the filter parameters in the corresponding relationship. In the present application, a passive method of a passive filter is used to suppress a pulsating current in the energy storage system, the pulsating current being suppressed by means of the arrangement of an LC filter in the sub-modules; the parameters of the LC filter in each sub-module are all determined on the basis of relevant parameters of the energy storage system and the correlation between filter parameters in the sub-module and the relevant parameters; thus, accurate passive filter parameters can be obtained, to thereby accurately suppress a current pulsating current in the energy storage system.
The application provides a dynamic voltage support method and apparatus of an energy storage converter, a device and a storage medium, relating to the technical field of grid-connected transformation. The dynamic voltage support method of the energy storage converter comprises: obtaining preset reference value data and output electric information of the energy storage converter; in response to the output electric information, obtaining active power information, reactive power information and voltage amplitude information of a grid-connected point; in response to one or more of the preset reference value data, the active power information, the reactive power information and the voltage amplitude information, obtaining grid-connected regulation and control data of the energy storage converter, and by means of the grid-connected regulation and control data, controlling the energy storage converter to carry out dynamic voltage support regulation dynamic voltage of grid-connected transformation. The method can improve the dynamic voltage support capability of the energy storage converter, and improve the stability of grid-connected regulation and control.
H02J 3/48 - Dispositions pour l’alimentation en parallèle d’un seul réseau, par plusieurs générateurs, convertisseurs ou transformateurs contrôlant la répartition de puissance entre les générateurs, convertisseurs ou transformateurs contrôlant la répartition de la composante en phase
65.
MULTISCALE METALLIC METAMATERIAL, AND PREPARATION METHOD AND USE THEREOF
Disclosed are a multiscale metallic metamaterial, and a preparation method and use thereof. The preparation method includes: preparing a 3D printed metallic material by 3D printing using a metal alloy powder as a raw material, the 3D printed metallic material having a micron-scale pore-array structure; annealing the 3D printed metallic material to obtain an annealed metallic material; and immersing the annealed metallic material in a chemical etching solution, and performing dealloying, to obtain the multiscale metallic metamaterial.
B22F 10/62 - Traitement de pièces ou d'articles après leur formation par des moyens chimiques
B22F 5/10 - Fabrication de pièces ou d'objets à partir de poudres métalliques caractérisée par la forme particulière du produit à réaliser d'articles avec des cavités ou des trous, non prévue dans les sous-groupes précédents
B22F 10/28 - Fusion sur lit de poudre, p. ex. fusion sélective par laser [FSL] ou fusion par faisceau d’électrons [EBM]
B22F 10/64 - Traitement de pièces ou d'articles après leur formation par des moyens thermiques
Aspects of the disclosure provide a method for sensing beam management in an integrated sensing and communications network. The method can include jointly designing the TX and RX beampatterns during beam sweeping and beam tracking in the monostatic and bistatic sensing scenarios, respectively; the procedures of sensing beam management are proposed for the corresponding case during beam sweeping; and associating carrier and RS configurations indicating the resource allocation in the time and frequency domain in each carrier with different sensing requirements. The number and placement of resources for beam sweeping can be dynamically adjusted; and the signaling interaction mechanism is designed for the corresponding case of beam sweeping in monostatic and bistatic sensing scenarios, respectively.
H04B 7/06 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées à la station d'émission
67.
Methods For Sensing Beam Management In Integrated Sensing And Communications System
Various solutions for sensing beam management in integrated sensing and communications (ISAC) system are described. From the receiver's perspective, a sensing receiver may determine or receive a beam configuration and a reference signal (RS) configuration for a sensing of a target object. The sensing receiver may further perform sweeping(s) of receiving (Rx) beam(s) to receive RS(s) based on the beam configuration and the RS configuration. Then, the sensing receiver may perform the sensing of the target object based on the RSs. From the transmitter's perspective, a sensing transmitter may determine or transmit the beam configuration and the RS configuration for the sensing of the target object, and then perform sweeping(s) of transmitting (Tx) beam(s) to transmit the RS(s) based on the beam configuration and the RS configuration.
H04B 7/06 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées à la station d'émission
H04B 17/309 - Mesure ou estimation des paramètres de qualité d’un canal
H04L 5/00 - Dispositions destinées à permettre l'usage multiple de la voie de transmission
68.
APPROXIMATE NEAREST NEIGHBOR SEARCH METHOD AND SYSTEM BASED ON RAY TRACING INTERSECTION, MEDIUM, AND DEVICE
The present application provides an approximate nearest neighbor search (ANNS) method and system based on ray tracing intersection, a medium, and a device. The method comprises: filtering search points to obtain codebook entries and subspace-level inverted indices; on the basis of ray tracing intersection conditions, screening the codebook entries to construct a subspace distance query table; and on the basis of the subspace distance query table and the subspace-level inverted indices, querying a distance to obtain an ANNS result. According to the present application, a distance calculation operation in the construction of the subspace distance query table is replaced with a ray tracing intersection test, and intersection values in different table entry sub-spaces are used as distances for selective distance calculation, so that the search efficiency of ANNS based on IVFPQ is improved.
A Cas12 protein and the use thereof. The Cas12 protein has an amino acid sequence having at least 90% sequence identity with a sequence as set forth in SEQ ID NO: 1 or a homologous sequence thereof, and the amino acid sequence of the Cas12 protein is not SEQ ID NO: 1. The Cas12 protein has good thermal stability and trans-cleavage activity, which is beneficial for the storage and transportation of the Cas12 protein in practical applications, increases application scenarios of the Cas12 protein and a CRISPR system based on the Cas12 protein, and provides more choices for users. In addition, on the basis of the existing theoretical foundation of protein engineering, the Cas12 protein mutant with improved thermal stability can also serve as a template/starting sequence for subsequent protein engineering.
A heat pump-driven regenerative direct air capture (DAC) system, comprising: a heat pump subsystem mainly formed by a heat pump condenser (21) and a heat pump evaporator (20) and a DAC subsystem mainly formed by a first adsorption bed (5), a second adsorption bed (6), and a first condenser (16) used for condensing produced gas. The heat pump condenser (21) is separately connected to heat exchange channels of the first adsorption bed (5) and the second adsorption bed (6) by means of a liquid inlet pipeline provided with a ninth switching valve (30) and a liquid return pipeline provided with a tenth switching valve (31) to form an internal heat source circulation pipeline. The heat pump evaporator (20) is connected to a medium pipeline of the first condenser (16) by means of a pipeline to form a condensation circulation pipeline.
B01D 53/04 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse avec adsorbants fixes
F17C 5/06 - Procédés ou appareils pour remplir des récipients sous pression de gaz liquéfiés, solidifiés ou comprimés pour le remplissage avec des gaz comprimés
71.
CHIRAL BIMETALLIC COOPERATIVE CATALYSIS SYSTEM CONTAINING CHELATING LIGAND AND USE THEREOF IN ASYMMETRIC SYNTHESIS OF BEDAQUILINE
A chiral bimetallic cooperative catalysis system containing a chelating ligand and use thereof in asymmetric synthesis of bedaquiline are provided. Specifically, in the chiral bimetallic cooperative catalysis system, an equilibrium constant of a reaction is increased by the chelating ligand formed by an achiral secondary amine and chiral lithium aminoalcohol, thereby promoting an addition reaction between 6-bromo-3-benzyl-2-methoxyquinoline (I) and 3-dimethylamino-1-naphthyl-1-propanone (II) to move forward. By means of the bimetallic cooperative catalysis system, the yield of the target product (1R,2S)-bedaquiline is obviously increased.
B01J 31/12 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des composés organométalliques ou des hydrures métalliques
B01J 31/18 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des complexes de coordination contenant de l'azote, du phosphore, de l'arsenic ou de l'antimoine
The present invention provides a method for managing heat-electric outputs of a high-proportion new energy system based on CSP-CHP combined energy supply, which belongs to the field of new energy system optimization and are used for solving the problems of insufficient flexibility of the high-proportion new energy system during the heating period and difficult consumption of renewable energy. The method includes: establishing a concentrating solar power (CSP) unit model and a combined heat and power (CHP) unit model based on the built structure; establishing a collaborative optimization model of the high-proportion new energy system based on the proposed unit models; acquiring relevant data of various units and renewable resource data; obtaining a sum of hourly electric power outputs and a sum of hourly heat outputs; and controlling a heat storage apparatus to store or output a certain amount of heat energy.
H02J 3/38 - Dispositions pour l’alimentation en parallèle d’un seul réseau, par plusieurs générateurs, convertisseurs ou transformateurs
F02C 1/00 - Ensembles fonctionnels de turbines à gaz caractérisés par l'utilisation de gaz chauds ou de gaz sous pression non chauffés, comme fluide de travail
F02C 6/14 - Ensembles fonctionnels de turbines à gaz comportant des moyens pour emmagasiner l'énergie, p. ex. pour faire face à des pointes de charge
G05B 17/02 - Systèmes impliquant l'usage de modèles ou de simulateurs desdits systèmes électriques
73.
USE OF SILICON DIOXIDE MICROSPHERES IN SYNTHESIS OF ULTRA-LONG OLIGONUCLEOTIDE AND METHOD FOR SYNTHESIZING ULTRA-LONG OLIGONUCLEOTIDE
The present invention relates to the technical field of oligonucleotide synthesis. Disclosed are the use of silicon dioxide microspheres in the synthesis of an ultra-long oligonucleotide and a method for synthesizing an ultra-long oligonucleotide, wherein the silicon dioxide microspheres have a specific surface area of less than 1 m2/g, and preferably, the silicon dioxide microspheres have modification groups on the surface. The method for synthesizing an ultra-long oligonucleotide comprises: performing a coupling reaction on a nucleoside phosphoramidite synthesis unit using the silicon dioxide microspheres having modification groups on the surface as carriers under coupling reaction conditions. The prepared carriers can be used to prepare an ultra-long oligonucleotide.
C07H 1/00 - Procédés de préparation des dérivés du sucre
C07H 21/00 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
74.
ARTIFICIAL SYNTHESIS METHOD FOR MALONYL-COA AND USE OF SAME
22, and pathway enzymes pyruvate dehydrogenase (PDH) and acetyl-CoA carboxylase (ACC) therein being strictly regulated, thereby achieving high yields of products using malonyl-CoA as a precursor, including flaviolin, caprylic acid, phloroglucinol, pentadecaheptaene, natamycin, spinosad, etc.
C12P 19/32 - Nucléotides avec un système cyclique condensé, contenant un cycle à six chaînons, comportant deux atomes d'azote dans le même cycle, p. ex. nucléotides puriques, dinucléotide de la nicotinamide-adénine
75.
PREPARATION METHOD FOR SPIROCYCLIC TETRAHYDRO-γ-CARBOLINE DERIVATIVE, AND USE OF SPIROCYCLIC TETRAHYDRO-γ-CARBOLINE DERIVATIVE
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (Chine)
Inventeur(s)
Zhang, Ao
Tang, Wei
Chen, Mingjie
Lei, Shuyue
Song, Zilan
Zhang, Xiaomeng
Abrégé
The present invention relates to a cGAS inhibitor, a preparation method therefor, and a use thereof. Specifically, the compound has a structure represented by formula (I), wherein the definitions of groups and substituents are as stated in the description. Also disclosed are a preparation method for the compound and a use of the compound in the prevention and/or treatment of inflammation, autoimmune diseases, neurodegenerative diseases, and other diseases.
A61K 31/403 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des carbocycles, p. ex. carbazole
A61K 31/438 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle le cycle étant condensé en spiro avec des systèmes carbocycliques ou hétérocycliques
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 37/06 - Immunosuppresseurs, p. ex. médicaments pour le traitement du rejet de greffe
76.
INTEGRATED OPERATION METHOD AND SYSTEM FOR PORT-AND-SHIP ENERGY AND TRANSPORTATION SYSTEM BASED ON LAYERED GAME
The method includes: S1: formulating a layered game architecture for a port-and-ship integrated energy and transportation operation; S2: establishing a port-and-ship layered game optimization model based on an optimized objective function and an optimized constraint condition of a port and an optimized objective function and an optimized constraint condition of a ship; and S3: based on the port-and-ship layered game optimization model, solving, by the layered game architecture, an optimal integrated operation method for the port-and-ship energy and transportation system through a KKT (Karush-Kuhn-Tucker) optimality condition solving method. The port-and-ship layered game optimization model means that the port, as a superior guider, formulates and executes a strategy, the ship, as an inferior follower, makes corresponding responses by taking the strategy formulated by the port as a constraint, and the ship updates its strategy according to the responses made by the ship till reaching a game equilibrium.
An artificial synthesis method for malonyl-CoA and use thereof are provided. By means of heterologous expression of an aminotransferase and a malonyl-CoA reductase, an artificial synthesis pathway for synthesizing malonyl-CoA by using β-alanine (β-ala) as a precursor is constructed as follows: firstly, under catalysis of a transaminase, β-ala transfers amino groups to α-ketonic acid (such as pyruvic acid, oxaloacetic acid, or α-ketoglutaric acid, etc.), to form an intermediate product 3-oxopropanoate and a corresponding amino acid; the 3-oxopropanoate generates malonyl-CoA under the action of the malonyl-CoA reductase. This pathway addresses the defects of the natural malonyl-CoA synthesis pathway, such as low carbon utilization, consumption of energy substance ATP, release of greenhouse gas CO2, and strict regulation of pathway enzymes, a pyruvate dehydrogenase (PDH) and an acetyl-CoA carboxylase (ACC), thereby achieving high yielding of products using malonyl-CoA as a precursor, including flaviolin, octanoic acid, phloroglucinol, pentadecaheptaene, natamycin, and spinosad.
C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
C12P 7/22 - Préparation de composés organiques contenant de l'oxygène contenant un groupe hydroxyle aromatiques
C12P 7/40 - Préparation de composés organiques contenant de l'oxygène contenant un groupe carboxyle
C12P 17/06 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'oxygène comme unique hétéro-atome du cycle contenant un hétérocycle à six chaînons, p. ex. fluorescéine
78.
OPTICAL TWO-WAY TIME AND FREQUENCY TRANSFER SYSTEM AND METHOD BASED ON VIRTUAL SYNTHETIC WAVELENGTHS
SJTU-PINGHU INSTITUTE OF INTELLIGENT OPTOELECTRONICS (Chine)
Inventeur(s)
Hu, Liang
Wu, Guiling
Chen, Jianping
Abrégé
An optical two-way time and frequency transfer system and method based on virtual synthetic wavelengths. A primary end and a secondary end respectively synthesize a plurality of wavelength signals into virtual synthetic wavelengths, so as to expand a time difference measurement range of an optical carrier; the primary end and the secondary end respectively send the virtual synthetic wavelengths to the secondary end and the primary end; the primary end and the secondary end each measure a time difference between a local virtual synthetic wavelength and the virtual synthetic wavelength that is received from the opposite end; in combination with coarse time difference measurement, the secondary end can obtain a clock difference between the primary and secondary ends by means of a two-way transfer principle, so as to complete two-way time and frequency transfer; in addition, the secondary end adjusts the frequency and phase of the optical carrier, such that time and frequency synchronization of the primary and secondary ends can be implemented. The preset invention overcomes the existing problem of a time difference measurement range in optical carrier time and frequency transfer being small and the other existing problem of the precision of a time and frequency transfer method based on electro-optical modulation being insufficient. The system has the advantages of a low noise floor, a simple structure and high reliability.
A use of phenyl-β-D-glucuronide in preparation of a drug for induced exhalation detection of cancer. The phenyl-β-D-glucuronide is present in natural organisms, is verified to have no toxic or side effects by means of animal experiments, and is safe and reliable. In addition, by means of the in-vivo tumor part, the phenyl-β-D-glucuronide can be decomposed into phenol which is almost absent in vivo as a specific marker, so that the impact of individual factors on the detection accuracy in exhalation detection methods can be avoided.
The present disclosure provides a system for IoT Botnet detection, comprising: a flow preprocessing device for processing the flow data packets to obtain NetFlow data; a flow clustering device for segmenting the NetFlow data to obtain flow points, and clustering the flow points to form botnet transactions or normal behavior transactions; a fingerprint generation device for extracting feature fingerprints from the obtained transactions and converting the feature fingerprints into RGB fingerprint images; and a classification device for detecting the fingerprint images and yielding the classification results.
A tumor vaccine, comprising and/or expressing an antigen molecule, a co-stimulatory signal molecule, a cytokine, and an NLRC5 molecule. The tumor vaccine can further comprise and/or express a CIITA molecule. Further provided is a use of the tumor vaccine in preventing and/or treating tumors.
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61K 38/00 - Préparations médicinales contenant des peptides
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
82.
CIRCUIT MODELING METHOD AND OUTPUT CURRENT CONTROL METHOD FOR DUAL-ACTIVE-BRIDGE-TYPE MICRO-INVERTER
The disclosure provides a circuit modeling method for a dual-active-bridge-type micro-inverter. The method equates dual-active-bridge-type micro-inverter to a standard dual-active-bridge circuit by establishing an equivalent circuit model, thereby establishing a third-order large signal model and a third-order small signal model of the micro-inverter, so as to facilitate the solution of a circuit state variable and the analysis of the dynamic performance.
G06F 30/367 - Vérification de la conception, p. ex. par simulation, programme de simulation avec emphase de circuit intégré [SPICE], méthodes directes ou de relaxation
H02M 7/5387 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs, p. ex. onduleurs à impulsions à un seul commutateur dans une configuration en pont
83.
WEAR STATE ONLINE MONITORING METHOD AND SYSTEM BASED ON TRANSFER LEARNING AND MULTI-SOURCE INFORMATION FUSION
A wear state online monitoring method and system based on transfer learning and multi-source information fusion are provided. The method includes: separately collecting data of a friction pair to be monitored in a friction and wear testing state and in an on-ship state; performing feature extraction on the data of the friction pair to be monitored; based on the extracted features, performing feature transferring through transfer learning to obtain successfully transferred features; training a random forest model by using the successfully transferred features, and performing wear state monitoring by using the trained random forest model. The application achieves online monitoring of the wear states of the shafting, gearbox, and wear-prone components in marine and aerospace power plants. The incorporation of transfer learning and multi-source information fusion reduces the quality requirements of the collected signals and enhances the robustness of wear state monitoring, thereby broadening the application scope of the system.
G06V 10/778 - Apprentissage de profils actif, p. ex. apprentissage en ligne des caractéristiques d’images ou de vidéos
G06V 10/26 - Segmentation de formes dans le champ d’imageDécoupage ou fusion d’éléments d’image visant à établir la région de motif, p. ex. techniques de regroupementDétection d’occlusion
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
84.
PRIVACY-PRESERVING DEEP MODEL CONSTRUCTION METHOD AND SYSTEM BASED ON DYNAMIC PROGRAMMING SOLUTION
Provided in the present invention are a privacy-preserving deep model construction method and system based on a dynamic programming solution. The method comprises: acquiring an initial neural network model, wherein the initial neural network model comprises a deep neural network model; performing node segmentation on the basis of the initial neural network model, so as to obtain different segmented subgraphs; performing local scheduling on the basis of the segmented subgraphs and by using a preset search mode, so as to obtain candidate options corresponding to current segmented subgraphs; and performing global scheduling on the basis of the candidate options, so as to obtain, by using dynamic programming, a target combination of candidate options corresponding to different segmented subgraphs, and outputting a privacy-preserving deep model on the basis of the target combination. In the present invention, a computational graph of a neural network model is analyzed by using a graph analysis method, and secure compilation is performed on the neural network model on the basis of a dynamic programming method, thereby ensuring the security and also obtaining a privacy-preserving deep model having an optimal performance.
A method for preparing bedaquiline using a low-temperature continuous flow, and a product prepared. The preparation method comprises the following steps: step S1, carrying out first continuous flow reaction on a feed liquid A and a feed liquid B by using a continuous flow to obtain a reaction liquid D; step S2, carrying out second continuous flow reaction on the reaction liquid D and a feed liquid C by using a continuous flow, wherein the reaction residence time of the first continuous flow reaction is 30-600 s, and the reaction residence time of the second continuous flow reaction is 30-200 s; and step S3, carrying out quenching. The preparation method achieves a good yield, and by using the method for preparation of bedaquiline, a crude product obtained requires only simple post-treatment to achieve a purity of pure bedaquiline of up to 99.8%.
The present invention provides an image compression error detection method, comprising: acquiring a training image data set; using an image compression model to extract a first latent feature representation of a training image, the first latent feature representation being a multi-channel latent feature representation for image compression; processing the first latent feature representation to obtain a stability measurement area for detecting an image compression error; and extracting a first latent feature representation of a test image, and comparing the first latent feature representation of the test image with the stability measurement area to obtain an image compression error detection result. On the basis of the image compression error detection method, an error-resilient image compression method and system are correspondingly provided. According to the present invention, the quality error and damage caused by neural network-based image compression can be efficiently detected, stable continuous image compression is efficiently realized, and the methods are applied to an actual image communication scenarios.
G06V 10/75 - Organisation de procédés de l’appariement, p. ex. comparaisons simultanées ou séquentielles des caractéristiques d’images ou de vidéosApproches-approximative-fine, p. ex. approches multi-échellesAppariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques utilisant l’analyse de contexteSélection des dictionnaires
G06V 10/40 - Extraction de caractéristiques d’images ou de vidéos
G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
A multistage water treatment system that requires minimum energy and can be powered by low-grade energy sources, such as sunlight, is disclosed. The system may include multiple stages, where each stage comprises a hydrophobic membrane, a confined saline layer, and a condenser. Using a saline layer as the evaporator, as confined by a hydrophobic membrane, strong thermohaline convection is initiated to mitigate salt accumulation and enhance heat transfer. The multistage water treatment system is salt-resistant during continuous desalination of nearly saturated saline. Such a system enables water treatment by low-grade heat with water production exceeding the single-stage limit and ultrahigh salinity. This system is useful for water treatment, including seawater desalination, wastewater reclamation, residential water softening, and salt production from brine/seawater.
A fluorocarbon/palladium/magnesium-scandium hydrogen-chromic film and a preparation method thereof are provided. The film includes a magnesium-scandium composite film layer, a palladium catalytic layer, and a fluorocarbon film layer that are sequentially arranged on a substrate. The preparation method includes: growing the magnesium-scandium composite film layer on the substrate first, then growing the palladium catalytic layer in situ on the magnesium-scandium layer, and finally depositing the fluorocarbon film layer on Pd. According to the present invention, the catalytic effect of palladium is utilized to promote reversible conversion between hydrogen and hydrogen atoms during hydrogen absorption and dehydrogenation stages, and a composite scandium element is added to accelerate diffusion of the hydrogen atoms in a magnesium matrix and accelerate formation and decomposition of a hydride, such that the film can be repeatedly and rapidly switched between a reflective state and a transparent state.
A preparation method of an indium phosphide quantum dot (InP QD) with a large Stokes shift includes: fully dissolving the indium precursor at a first temperature under isolation from oxygen and water, adding a phosphorus precursor, and heating to a second temperature to allow a reaction to obtain an indium phosphide (InP) core; adding a shell precursor to the InP core, and heating to a third temperature to obtain QD with a core-shell structure; and adding anionic and cationic precursors successively to the QD with the core-shell structure at the third temperature to obtain the InP QD with an emission peak adjustable in a range of 465 nm to 650 nm, a high quantum efficiency, and a large Stokes shift. The InP QD mainly has a large Stokes shift to inhibit self-absorption and non-radiative resonance energy transfer.
C09K 11/62 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du gallium, de l'indium ou du thalium
90.
MAGNESIUM-BASED SOLID HYDROGEN STORAGE ALLOY IN-SITU HYDROGEN ABSORPTION AND HYDROLYTIC HYDROGEN PRODUCTION DEVICE, AND USE THEREOF
The present application belongs to the field of hydrogen preparation and storage equipment. Disclosed are a magnesium-based solid hydrogen storage alloy in-situ hydrogen absorption and hydrolytic hydrogen production device, and the use thereof. The device provided in the present application can achieve controllable hydrogen charging and hydrolytic hydrogen production of a magnesium alloy material in the same tank, thereby greatly improving the hydrolytic hydrogen production efficiency of a magnesium hydrogen storage material and shortening the manufacturing time of a system. In the device, hydrogen can be directly introduced into a stainless steel tank (1), such that hydrogen is absorbed by a magnesium alloy, so as to generate a hydrogenated magnesium alloy, and water is introduced when hydrogen is required for use later to hydrolyze the hydrogenated magnesium alloy, so as to produce hydrogen. During the process, the magnesium alloy does not need to be taken out and exposed to air after hydrogen absorption, nor needs to be further treated, and the hydrogen absorption and hydrolytic hydrogen production of the magnesium alloy can be finished stepwise in the same device, this process greatly saving on the manufacturing time and cost of a hydrolytic hydrogen production tank.
C01B 3/00 - HydrogèneMélanges gazeux contenant de l'hydrogèneSéparation de l'hydrogène à partir de mélanges en contenantPurification de l'hydrogène
C01B 3/06 - Production d'hydrogène ou de mélanges gazeux contenant de l'hydrogène par réaction de composés inorganiques comportant un hydrogène lié électropositivement, p. ex. de l'eau, des acides, des bases, de l'ammoniac, avec des agents réducteurs inorganiques
91.
TWO-STAGE MULTI-TASK LEARNING-BASED METHOD AND SYSTEM FOR AUTOMATED LESION RESPONSE ASSESSMENT
A two-stage multi-task learning based method is disclosed for automated lesion response assessment according to Response Evaluation Criteria in Solid Tumors (RECIST). Pre-processed venous phase CT scans are inputted into a convolutional neural network (CNN) and a transformer to obtain coarse lesion segmentation masks, which are then optimized by a multi-task learning framework that incorporates longitudinal CT correlation and clinical prior knowledge to generate difference maps, and adopts an ordinal regression strategy that encodes the ground truth of response outcome. Sum of the volume (SOV) -based response assessment and new lesion assessment results are combined to obtain the overall RECIST response, i. e., response, stable disease, and progressive disease.
Provided are a point cloud quality evaluation method and device and a storage medium. The method includes: selecting the target number of reference point cloud regions from a reference point cloud according to a preset region selection rule (S110); selecting to-be-evaluated point cloud regions respectively corresponding to the target number of reference point cloud regions from a to-be-evaluated point cloud corresponding to the reference point cloud (S120); successively performing at least one scale transformation on the reference point cloud region and a respective to-be-evaluated point cloud region to generate corresponding new reference point cloud regions and corresponding new to-be-evaluated point cloud regions (S130); separately performing a quality evaluation on each new reference point cloud region and a respective new to-be-evaluated point cloud region to obtain a corresponding quality evaluation value (S140); and fusing all quality evaluation values to obtain a corresponding multi-scale quality evaluation value (S150).
The present invention provides an saCas9 sgRNA targeting TTR and a modification mode thereof. The modified saCas9 sgRNA comprises a guide RNA having a length of 20 to 22 nucleotides and an sgRNA scaffold having a length of 77 nucleotides, and the nucleotide sequence of the saCas9 sgRNA comprises at least one chemical modification; and the saCas9 sgRNA targeting TTR comprises a guide RNA at the 5' end, and the sequence of the guide RNA is at least 20, at least 21, or all 22 consecutive nucleotides of a nucleotide sequence as shown in any one of SEQ ID NOs: 1-9. The saCas9 sgRNA provided by the present invention can significantly improve the editing activity and reduce the off-target effects.
Provided are a biomass-derived carbon particle, and a preparation method and use thereof. The biomass-derived carbon particle includes a non-graphitized biochar and a graphitized biochar; where the non-graphitized biochar and the graphitized biochar each have an oxygen-containing functional group; and the oxygen-containing functional group includes one selected from the group consisting of hydroxyl group, phenolic hydroxyl group, carbonyl group, and ether group.
Provided are a hollow radioactive containment fuel containing a burnable poison, a preparation method therefor and the use thereof. The hollow radioactive containment fuel containing a burnable poison comprises a hollow fuel area and a fuel-free protective layer covering the periphery of the fuel area; the hollow fuel area comprises a matrix, and a fuel element and a burnable poison which are distributed in the matrix, wherein the fuel element is an isotropic coated fuel particle, and the burnable poison is an isotropic coated burnable poison particle. The present invention can realize highly compact and safe radioactive containment of a reactor fuel, ensure that radioactive products, especially fission gas, are not released into the environment accidentally, stably provide a fission site for the core of a miniature nuclear power pile for a long period of time, effectively confine the radioactive fission products inside the fuel, and guarantee the safe and stable operation of a reactor.
Provided in the present invention are a high-concurrency read-write optimization system for a distributed file system, and a medium and a device. The high-concurrency read-write optimization system comprises: a data read-write concurrency control module, which uses a fine-grained read-write lock to ensure data consistency and high concurrency; a file data cache module, which controls a client system to cache data of a server-side file system; a read-write request delay prediction module, which predicts a running delay of a file read-write request from a client, so as to provide a path optimization scheme; and a read-write task execution module, which ensures read-write performance under a high-concurrency condition by means of simultaneously executing local and remote data read-write operations. The present invention mainly provides a new data read-write optimization system for solving the problem of the performance of a distributed file system constructed on the basis of a non-volatile memory and RDMA technology having a bottleneck regarding a high-concurrency read-write task. The present invention improves the bandwidth utilization rate of a distributed file system for a storage device and a network device, thereby improving the overall performance of a system read-write file.
Provided in the present invention are a superconducting strip structure for improving the resistance of a superconducting constant-current switch, and a manufacturing method. The structure comprises conductive layers, a superconducting layer, a buffer layer and a substrate layer, wherein the substrate layer, the buffer layer and the superconducting layer are sequentially arranged in a stacked manner; and the face of the superconducting layer that faces away from the buffer layer comprises, along a strip, at least two conductive layers arranged spaced apart from each other, and a superconducting path for communicating the two conductive layers is arranged on the superconducting layer. The superconducting path is arranged on the superconducting layer between the two conductive layers, so that the current can only flow from one conductive layer to the other conductive layer by means of the superconducting path. Therefore, the characteristic of the superconducting layer, when in a non-superconducting state, presenting a relatively large resistance can be utilized, so that the whole superconducting constant-current switch presents a relatively large resistance. The switch has a small structure and is capable of performing fast switching. The resistance of the superconducting constant-current switch, when turned on, can further be increased by means of reducing the conduction cross-sectional area of the superconducting path and increasing the path length of the superconducting path.
H01B 12/06 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par leurs formes à couches ou fils déposés sur des supports ou des noyaux
98.
BIONIC FINGER, FIXTURE, AND MANUFACTURING METHOD FOR BIONIC FINGER
A bionic finger (10), comprising: skin (100), an elastomer (200), a rigid supporting member (300) and a liquid delivery tube (400), wherein the skin (100) is provided with first liquid output holes (110); the elastomer (200) is wrapped and mounted in the skin (100), the elastomer (200) is provided with second liquid output holes (210), and the rigid supporting member (300) is wrapped and mounted in the skin (100); and a side portion of a first end (401) of the liquid delivery tube (400) is provided with third liquid output holes (410), the third liquid output holes (410), the second liquid output holes (210) and the first liquid output holes (110) are in communication with each other, and a second end (402) of the liquid delivery tube (400) extends to the outside of the skin (100). When the skin (100) of the bionic finger (10) comes into contact with a grabbed object, a liquid can flow from the second end (402) of the liquid delivery tube (400) located outside the skin (100) to the first end (401) of the liquid delivery tube (400) located inside the skin (100), and reaches a position between the skin (100) and the grabbed object sequentially through the third liquid output holes (410), the second liquid output holes (210) and the first liquid output holes (110), such that a friction coefficient between the bionic finger (10) and the grabbed object is changed, and thus a friction force between the bionic finger and the grabbed object is changed, thereby solving the technical problem of being unable to adjust the friction force with the bionic finger. Further provided are a fixture, and a manufacturing method for the bionic finger.
Provided are a hierarchical porous defect UiO-66 material and a preparation method thereof. The method includes the following steps: mixing a zirconium ion source, a mixed ligand, an organic acid, an organic good solvent, and water to obtain a mixture; and subjecting the mixture to reaction while heating, washing, freeze-drying, and heat treatment in sequence to obtain the hierarchical porous defect UiO-66 material; where hierarchical pores of the hierarchical porous defect UiO-66 material comprise micropores and mesopores; the micropores each have a pore size of not greater than 2 nm; the mesopores each have a pore size of 2 nm to 4 nm; the mixed ligand includes terephthalic acid and a trisubstituted benzene series; and the trisubstituted benzene series is one or two selected from the group consisting of 2-aminoterephthalic acid and 2-aminoisophthalic acid.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
C07F 7/00 - Composés contenant des éléments des groupes 4 ou 14 du tableau périodique
The present disclosure provides a PROTRACTOR isothermal nucleic acid detection method, comprising: S1, extracting total nucleic acid from a sample to be detected; S2, configuring a reaction system, the reaction system including a single-stranded DNA (ssDNA) probe, an RNA fluorescent probe, a DNA ligase or a variant thereof, an RNA polymerase or a variant thereof, a guide RNA or a derivative thereof, a CRISPR-related Cas protein or a variant thereof, and a PROTRACTOR reaction buffer; wherein the ssDNA probe is specifically complementary to a strand of a target nucleic acid molecule; S3, adding the total nucleic acid extracted in the step S1 to the reaction system of the step S2 to perform thermostatic reaction and generating a fluorescent signal; wherein the ssDNA probe forms a single-stranded circular DNA probe under the action of the DNA ligase or the variant thereof in a process of thermostatic reaction; and S4, reading and recording the fluorescent signal generated in the step S3, and determining presence or absence of the target nucleic acid molecule in the sample to be detected by the fluorescent signal.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
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