Abrégé

The present invention relates to a thrombus removal system and an assisted recovery system. The thrombus removal system comprises: a thrombus retrieval device, comprising a push-pull guide wire and a thrombus retrieval stent that are sequentially connected in the axial direction of the thrombus retrieval device; and an assisted recovery system, comprising a recovery catheter, a push-pull device, and a self-expansion stent, wherein the proximal end of the self-expansion stent is connected to the distal end of the push-pull device; the push-pull device is used for being slidably arranged in the recovery catheter and used for pushing and pulling the self-expansion stent in the axial direction of the recovery catheter; the self-expansion stent has a compressed state when being delivered in the recovery catheter and an expanded state when being partially separated from the recovery catheter; the assisted recovery system is used for moving along the push-pull guide wire to be positioned on the proximal side of the thrombus retrieval stent, and then the self-expansion stent is partially separated from the recovery catheter to be expanded; when capturing a target object, the thrombus retrieval stent moves towards the proximal side under the pulling of the push-pull guide wire to at least partially enter the self-expansion stent, so that the thrombus retrieval stent is withdrawn under the protection of the self-expansion stent, thereby preventing a thrombus from entering a side branch vessel blood and a blood vessel at a distal end.

Classes IPC  ?

• A61B 17/221 - Dispositifs de préhension des calculs en forme de boucles ou de paniers

Abrégé

The present invention provides a molybdenum-based alloy and a preparation method therefor, and a medical implant device and a preparation method therefor. The molybdenum-based alloy comprises a molybdenum matrix, polydopamine, and an alloy element, wherein the alloy element comprises at least one of a strengthening-toughening alloy element and a purification alloy element, the strengthening-toughening alloy element comprises at least one of a tantalum element, an iridium element, and a platinum element, and the purification alloy element comprises at least one of a strontium element, a titanium element, and a cerium element. The medical implant device is made of the molybdenum-based alloy. The present invention can solve the problems of room-temperature brittleness and anisotropy of molybdenum-based alloys, thereby improving the comprehensive performance of the molybdenum-based alloys, guaranteeing that a medical implant device such as a vascular stent prepared from the molybdenum-based alloy provided by the present invention has excellent mechanical properties under an in vivo use temperature condition.

Classes IPC  ?

• C22C 27/04 - Alliages à base de tungstène ou de molybdène
• A61L 31/10 - Matériaux macromoléculaires
• A61L 31/18 - Matériaux au moins partiellement opaques aux rayons X ou au laser
• C22C 1/05 - Mélanges de poudre métallique et de poudre non métallique
• B22F 3/0 -
• B22F 1/142 - Traitement thermique ou thermomécanique
• B22F 1/102 - Poudres métalliques revêtues de matériaux organiques
• B22F 3/24 - Traitement ultérieur des pièces ou objets
• B22F 3/10 - Frittage seul
• B23P 15/00 - Fabrication d'objets déterminés par des opérations non couvertes par une seule autre sous-classe ou un groupe de la présente sous-classe
• A61L 31/02 - Matériaux inorganiques

Abrégé

Provided in the present invention are a medical device and system, and a preparation method. The medical device comprises a base body and a coating, wherein the base body can expand or retract in the radial direction thereof, the coating is arranged in at least a partial region of the outer surface of the base body, and the coating comprises a protein and a cross-linking agent. The base body can be a balloon body. After the base body is introduced into a diseased blood vessel, the protein can be cross-linked with the protein on a blood vessel wall under the action of the cross-linking agent, so as to form a "protein micro-scaffold" in situ to support the blood vessel wall, thus maintaining vascular gain, maintaining vascular dilatation size, and reducing the possibility of vascular restenosis.

Classes IPC  ?

• A61L 29/08 - Matériaux de revêtement
• A61L 29/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61M 25/10 - Cathéters à ballon
• A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents
• A61F 2/88 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles les éléments filiformes étant sous forme d’enroulements hélicoïdaux ou en spirale
• A61F 2/90 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles
• A61F 2/86 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles
• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps

Produits et services

Catheters; Trocars; Electrodes for medical use; Medical apparatus and instruments for treating cardiovascular disease; Medical gloves; Medical guidewires; Medical instruments for intraluminal emplacement of stents or of synthetic stent grafts, namely, stent or synthetic stent graft delivery systems; Medical, surgical and orthopaedic implants made of artificial materials; Orthopaedic hip prostheses; Surgical implants comprised of artificial materials; Suture materials; Synthetic stent grafts

Abrégé

A balloon catheter, comprising a balloon body (100) and a coating film (200). The balloon body (100) is provided with a filling chamber for accommodating a filling agent to fill the balloon body (100); and the cross section of the balloon body (100), which is in a filled state, comprises peak portions (110) and valley portions (120) alternately arranged in a circumferential direction of the balloon body (100). The coating film (200) coats a circumferential surface of the balloon body (100) and is connected to the peak portions (110); and fluid passages (101) are formed between the coating film (200) and the valley portions (120), and the fluid passages (101) are isolated from the filling chamber. The balloon body (100) of the balloon catheter can be introduced into a blood vessel and enlarge the blood vessel without blocking a blood flow in the blood vessel, such that the balloon body (100) can maintain a relatively long enlarged time, and the treatment effect can be improved.

Classes IPC  ?

• A61M 25/10 - Cathéters à ballon
• A61M 25/00 - CathétersSondes creuses

Abrégé

Provided in the present invention is a balloon catheter, comprising a balloon assembly and a catheter assembly. The balloon assembly comprises a balloon body, the balloon body comprising a plurality of sub-balloons connected to each other, and each sub-balloon being of a hollow ring-shaped structure. All the sub-balloons are coaxially arranged, and the inner rings of all the sub-balloons jointly constitute a fluid flow channel which axially passes through the balloon body. The distal end of the catheter assembly passes through the fluid flow channel, the distal end of the catheter assembly being at least connected to the most distal sub-balloon. The catheter assembly is further provided with a liquid injection channel, the liquid injection channel communicating with all the sub-balloons. The liquid injection channel is used for enabling a filling agent to flow, so as to allow all the sub-balloons to be perfused with the filling agent, thereby filling the balloon body. During use, the balloon catheter does not block the blood flow in a blood vessel, and naturally will not cause ischemia of downstream tissue, which allows the balloon to be expanded for a relatively long time, such that a drug on the outer surface of the balloon assembly can be fully absorbed by the vascular wall, thereby improving treatment effect.

Classes IPC  ?

• A61M 25/10 - Cathéters à ballon

Abrégé

A medical device, comprising a sheath assembly (1000), a catheter assembly (2000), and an expansion assembly (3000). The catheter assembly (2000) is partially provided in the sheath assembly (1000), the catheter assembly (2000) comprises a first tube body (2100), and an axially relative movement can be generated between the first tube body (2100) and the sheath assembly (1000); the expansion assembly (3000) is sleeved on the outer peripheral surface of the distal end of the first tube body (2100), and the outer surface of the expansion assembly (3000) is used for loading drugs. The medical device is configured so that, by means of an axially relative movement between the sheath assembly (1000) and the first tube body (2100), the expansion assembly (3000) is covered by the sheath assembly (1000) to be in a radially compressed state or the expansion assembly (3000) is at least partially exposed outside the sheath assembly (1000) to be in a radially expanded state; the expansion assembly (3000) in a radially expanded state has a first fluid channel (3001) extending axially therethrough. The medical device can treat atherosclerosis, does not block the blood flow, can prolong the treatment time, and has a good treatment effect.

Classes IPC  ?

• A61M 25/00 - CathétersSondes creuses
• A61M 25/04 - Dispositifs de maintien en position, p. ex. sur le corps à l'intérieur du corps, p. ex. expansibles
• A61M 29/00 - Dilatateurs avec ou sans moyens pour introduire des agents, p. ex. des remèdes

Abrégé

A stent for a blood vessel includes a covering membrane and anchoring members connected to the covering membrane. The anchoring members are configured to secure the covering membrane within the blood vessel. The covering membrane is configured to pocket a diseased area of the blood vessel. The anchoring members are configured to sufficiently attach the covering membrane to the intima of the blood vessel when the stent is subjected to blood flow, fixing the covering membrane in the intended implantation position. The covering membrane can pocket the unstable plaque on the blood vessel intima, preventing rupture of the unstable plaque.

Classes IPC  ?

• A61F 2/07 - Endoprothèses déployables couvertes
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur

Abrégé

The present invention provides a medical device and a medical system. The medical system comprises the medical device, a conveying device, and a suction device. The medical device comprises a supporting component and a net-shaped capturing device; the net-shaped capturing device is assembled on the periphery of the distal end of the supporting component; a plurality of capturing units of the net-shaped capturing device are sequentially arranged at intervals in the axial direction of the supporting component; a first capturing unit among the plurality of capturing units is farther away from the proximal end of the supporting component than second capturing units; the first capturing unit is provided with a first capturing net surface which is overturned outwards in the whole circumference of the first capturing unit and bent towards the proximal end; each second capturing unit is provided with a second capturing net surface which radially protrudes outwards in the partial circumference of the second capturing unit; and the second capturing net surfaces of two adjacent second capturing units can form a circumferentially complete capturing net surface in the circumferential direction of the supporting component, such that the flexibility and supporting performance are both achieved, additionally, obstructions having old-fashioned and high-adhesiveness characteristics in lumens are effectively removed, and the obstructions are prevented from escaping.

Classes IPC  ?

• A61B 17/221 - Dispositifs de préhension des calculs en forme de boucles ou de paniers
• A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins

Abrégé

The present invention provides a retrieval stent, a retrieval device, and a retrieval system. The retrieval system comprises a retrieval device, a delivery device, and an aspiration device; the delivery device loads the retrieval device to deliver the retrieval device to a target lesion position; the aspiration device is connected to the delivery device and applies an aspiration force by means of the delivery device to aspirate an embolus at the target lesion position; the retrieval device comprises a core tube and a retrieval stent, wherein the retrieval stent is arranged on the periphery of a distal end of the core tube and the retrieval stent is connected to the core tube by means of a proximal loading section; the retrieval stent can be self-expanded to be deployed and is made of a mesh tube, a part of the mesh tube is turned over towards the exterior of the mesh tube to form a distal bent section of the retrieval stent, and the other part of the mesh tube which is not turned over forms the proximal loading section of the retrieval stent, and the distal bent section is provided with a concave umbrella-shaped mesh face facing a proximal end. Finally, the treatment efficiency and the treatment effect for emboli such as thrombus and calculus are improved.

Classes IPC  ?

• A61B 17/221 - Dispositifs de préhension des calculs en forme de boucles ou de paniers

Abrégé

Provided in the present invention are an embolus retrieval device and an embolus retriever. The embolus retriever comprises an embolus retrieval component and a control component, wherein the embolus retrieval component comprises an embolus retrieval stent, which comprises an outer-layer mesh pocket stent and an inner-layer mesh pocket stent nested in the outer-layer mesh pocket stent; the control component comprises a movement control member and a mounting member; the movement control member passes through the mounting member, and extends out of a distal end of the mounting member and is then connected to a distal end of the embolus retrieval stent; a proximal end of the outer-layer mesh pocket stent is connected to the mounting member; and a proximal end of the inner-layer mesh pocket stent is connected to the mounting member or the movement control member. When the movement control member moves towards a proximal end or a distal end of the embolus retriever, the movement control member controls the embolus retrieval stent to change the diameter, such that the embolus retriever can adapt to various lumens, and can effectively remove an embolus while reducing damage to each lumen.

Classes IPC  ?

• A61B 17/221 - Dispositifs de préhension des calculs en forme de boucles ou de paniers
• A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins

Abrégé

The present invention relates to a spring coil conveying device and a spring coil system. The spring coil system comprises a spring coil and a spring coil conveying device, and the conveying device comprises a pushing rod and an operating piece. A notch is formed in the peripheral surface of the distal end of the pushing rod. The operating piece is placed in the pushing rod and extends in the axial direction of the pushing rod, the proximal end of the operating piece is arranged at the proximal end of the pushing rod, and the distal end of the operating piece extends to the notch in the axial direction of the pushing rod, so that the conveying device is sleeved with a connecting piece of the spring coil by means of the notch. The connecting piece is limited in the notch by means of the operating piece to achieve connection between the conveying device and the spring coil, and then when the operating piece is stressed to move towards the proximal end of the pushing rod and releases the limiting of the operating piece on the connecting piece, the connecting piece may be separated from the notch to complete disengagement. The present invention may solve the problems of structural design being complex and the difficulty of a preparation process being high which are present in the existing mechanical disengagement mode.

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical

Abrégé

The present application relates to the field of pharmaceutical technology, in particular, to a drug-loaded medical device, including a medical device body and at least one drug coating, the drug coating is attached to at least one side of a surface of the medical device body. The main component of the drug coating includes a macrolide drug. The drug coating includes elongated prismatic crystals each with at least three lateral edges, and/or the drug coating includes crystal clusters of the elongated prismatic crystals each with at least three lateral edges. An aspect ratio of each elongated prismatic crystal is in a range from 1:1 to 40:1.

Classes IPC  ?

• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine

Abrégé

The present disclosure relates to a medical device. The medical device comprises a matrix and a first coating coated on the matrix. The matrix contains a metal element X having a content of ≥5 wt %; the first coating is at least one of an elemental metal layer of the metal element X, an alloy layer of the metal element X, and a metal-ceramic layer of the metal element X; and the first coating does not contain nickel and cobalt. The medical device has good use safety, reliability, and biocompatibility, so that a product can meet a use requirement of large plastic deformation, and has good reliability during use. The medical device can particularly meet requirements of product with large plastic deformation during use, such as medical implant devices.

Classes IPC  ?

• A61L 31/08 - Matériaux de revêtement
• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques

Abrégé

The present invention provides a plaque treatment device, which comprises a catheter, a plaque damage mechanism, and a content recovery mechanism. The plaque damage mechanism is configured to switch between an execution state and a first stand-by state, wherein the plaque damage mechanism in the first stand-by state is loaded in the catheter and used for moving along with the catheter, and the plaque damage mechanism in the execution state is used for damaging the covering wall of a target plaque. The content recovery mechanism is used for recovering the content of the target plaque. By means of the configuration, the plaque damage mechanism can be used for damaging the covering wall of the target plaque in a physical manner, such that the content of the target plaque can be recovered by the content recovery mechanism, without causing harm in blood circulation. For vulnerable plaques, the plaque treatment device provides a mechanical treatment manner and has the advantages of rapidly solving the fundamental problem, realizing precise treatment, and achieving the purpose of rapidly and thoroughly treating vulnerable plaques.

Classes IPC  ?

• A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
• A61B 17/32 - Instruments chirurgicaux coupants

Abrégé

The present application relates to a vascular stent, comprising a stent front segment (10), a stent middle segment (20), and a stent rear segment (30) connected in sequence. An anchoring protrusion (50) is arranged on the outer surface of the stent front segment (10) and/or the stent rear segment (30). When the vascular stent is in an unfolded state, the inner diameter of the stent middle segment (20) is smaller than those of the stent front segment (10) and the stent rear segment (30). The stent front segment (10) is configured for contacting the inner wall of the blood vessel (40). The stent rear segment (30) is configured for contacting the inner wall of the blood vessel (40). The anchoring protrusion (50) is configured for anchoring the vascular stent. That is, the anchoring protrusion (50) is attached to the inner wall of the blood vessel (40) and inserted into the blood vessel (40) for anchoring.

Classes IPC  ?

• A61F 2/90 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles

Abrégé

The present invention relates to a medical interventional catheter, which comprises a catheter body that integrates diagnosis and treatment. The catheter body comprises a functional part located at the distal end. The functional part is used for imaging monitoring in a target lumen and is further used for releasing a therapeutic source to a target position in the target lumen. The therapeutic source comprises therapeutic energy and/or a therapeutic substance. The medical interventional catheter of the present invention integrates diagnosis and treatment, so that real-time imaging monitoring in the therapeutic process can be achieved, thereby improving the therapeutic accuracy and effectiveness.

Classes IPC  ?

• A61M 25/00 - CathétersSondes creuses
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
• A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
• A61B 18/14 - Sondes ou électrodes à cet effet
• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
• A61N 5/067 - Thérapie par radiations utilisant un rayonnement lumineux utilisant un rayonnement laser
• A61N 7/00 - Thérapie par ultrasons

Abrégé

The present invention relates to a medical catheter, which comprises a catheter main body and a bending control component. The catheter main body comprises a proximal end part and a distal end part located at a distal end of the catheter main body. The distal end part is used for imaging monitoring and is also used for releasing treatment energy and/or a therapeutic agent. The distal end part is connected to the bending control component and is used for being bent relative to the proximal end part under control of the bending control component. The present invention relates to a medical catheter, which comprises a catheter main body and a bending control component. The catheter main body comprises a proximal end part and a distal end part located at a distal end of the catheter main body. The distal end part is used for imaging and monitoring and is also used for releasing treatment energy and/or a therapeutic agent. The distal end part is connected to the bending control component and is configured to bend relative to the proximal end part under the control of the bending control component.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
• A61B 1/005 - Endoscopes flexibles
• A61M 25/00 - CathétersSondes creuses
• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
• A61B 1/04 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision
• A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement

Abrégé

A vascular stent and a preparation method therefor. The vascular stent comprises a cylindrical stent and a limiting structure (200); the cylindrical stent comprises at least one flexible membrane (100), the circumferential direction of the cylindrical stent is defined as the direction of winding; the at least one flexible diaphragm (100) is wound in the direction of winding; and the limiting structure (200) is used for performing limiting on a flexible membrane (100) that is wound in a diameter reduction direction of the cylindrical stent.

Classes IPC  ?

• A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents

Abrégé

A drug delivery system includes a medical delivery device, a dispersed substance, a liquid dispersion medium and a balloon catheter. The medical delivery device includes a first housing member, a second housing member and a push mechanism. The first housing member defines a first storage chamber, and the second housing member is disposed over the first housing member and defines a second storage chamber. In a first operational configuration, the first storage chamber is not in communication with the second storage chamber. In a second operational configuration, the first storage chamber is in communication with the second storage chamber, allowing the liquid dispersion medium in the first storage chamber to enter the second storage chamber to be mixed with the dispersed substance to produce a dispersion system. In a third operational configuration, the push mechanism drives the first housing member to move relative to the second housing member.

Classes IPC  ?

• A61M 5/24 - Seringues à ampoules, c.-à-d. seringues à aiguille utilisables avec des ampoules ou des cartouches échangeables, p. ex. automatiques
• A61M 25/10 - Cathéters à ballon

Abrégé

The present application relates to a closure implant and a method for preparing same. The closure implant comprises a first coil (100) and an anti-unwinding component (200). The first coil (100) comprises at least one layer of unit coil layer (110); the unit coil layer (110) is formed by means of weaving at least one woven material; the woven material at least comprises a first wire; at least one part of the anti-unwinding component (200) is arranged in the first coil (100).

Classes IPC  ?

• A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins

Abrégé

The present invention relates to a ventricular function assistance device, a delivery and recovery system, and a ventricular function assistance system. The ventricular function assistance system comprises the ventricular function assistance device and the delivery and recovery system. The delivery and recovery system comprises a recovery device and a delivery device. The recovery device comprises a tightening mechanism, and the delivery device comprises a push rod and a delivery sheath. The far end of the push rod is configured to be detachably connected to a base, and the tightening mechanism is configured to be detachably connected to a support structure. The push rod and the tightening mechanism cooperate with each other to load the ventricular function assistance device into the delivery sheath. The ventricular function assistance device comprises a support structure and a base. The base is configured to be detachably connected to the push rod. The support structure comprises a plurality of struts, all of which are sequentially distributed in a circumferential direction of the base, with one end of each strut connected to the base and the other end being a free end. Additionally, drug-carrying grooves are formed in the outer surface of at least some of the struts. Therefore, drug utilization and long-term stability of adhesion are improved.

Classes IPC  ?

• A61F 2/24 - Valvules de cœur
• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
• A61F 2/966 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes possédant une gaine extérieure avec un mouvement longitudinal relatif entre la gaine extérieure et la prothèse, p. ex. utilisant une tige poussoir
• A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes

Abrégé

An occlusion stent (100) and a delivery system (200). A main body unit (500) is cylindrical, and has a proximal opening and a distal opening. An occlusion unit (600) has a proximal opening and a distal occlusion head. The proximal opening of the occlusion unit (600) is connected to the distal opening of the main body unit (500). The end opening area of the proximal opening of the main body unit (500) is larger than the end occlusion area of the distal occlusion head of the occlusion unit (600).

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical

Abrégé

Provided are an implantable medical device (100) and a method for manufacturing the same, and a method for manufacturing a stent. The implantable medical device (100) comprises a metal base (110) and a cladding layer (120). The cladding layer (120) is a nickel-free and cobalt-free metal layer which is deposited on the metal base (110) by means of a metal bond. The arrangement of the cladding layer (120) of the implantable medical device (100) on the metal substrate (110) can prevent carcinogenic elements in the metal base (110) such as nickel and cobalt from dissolution. Moreover, the cladding layer (120) is a nickel-free and cobalt-free metal layer, such that the implantable medical device (100) is free from problems of nickel or cobalt dissolution, thereby improving the biological safety of the implantable medical device (100).

Classes IPC  ?

• A61L 31/08 - Matériaux de revêtement
• A61F 2/91 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles fabriquée à partir de feuilles perforées ou de tubes perforés, p. ex. perforés par découpe au laser ou gravés
• A61L 31/02 - Matériaux inorganiques

Abrégé

A drug-loaded medical device, a preparation method therefor, a drug balloon and a method of preparing a drug coating are disclosed. The medical device or the drug balloon is provided on a surface thereof with a drug coating including a stabilizer and a drug. The stabilizer includes an amphiphilic triblock polymer with hydrophilic segments at both terminals, and the drug coating forms a nano-drug particle suspension in a water-soluble environment. In this way, the prepared nano-drug coating has high drug loading and can deliver the drug in a desirable way. In particular, when it comes into contact with water, the drug can be restored to the original nano size, almost without any particle size increase. This not only avoids the risk of embolism caused by granules, but also enables higher device safety, increased drug uptake and improved therapeutic effects.

Classes IPC  ?

• A61L 29/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 29/08 - Matériaux de revêtement
• A61L 29/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61L 29/18 - Matériaux au moins partiellement opaques aux rayons X ou au laser

Abrégé

A vascular stent, comprising a plurality of support rings (100) and a plurality of connection rods (200). The plurality of support rings (100) are distributed at intervals along the central axis of the vascular stent, each connection rod (200) is connected between every two adjacent support rings (100), and the wall thickness of at least a part of each connection rod (200) is less than the thickness of the plurality of support rings (100).

Classes IPC  ?

• A61F 2/915 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles fabriquée à partir de feuilles perforées ou de tubes perforés, p. ex. perforés par découpe au laser ou gravés avec des bandes présentant une structure en méandre, des bandes adjacentes étant reliées l’une à l’autre

Abrégé

Provided are a drug-loaded implantable medical instrument and a manufacturing method therefor. The drug-loaded implantable medical instrument (10) comprises an instrument body (100), a microporous membrane (200) fixed on the instrument body (100), and a nanocrystal medicament (300) loaded on the microporous membrane (200). A method for preparing a drug-loaded implantable medical device includes: providing a microporous membrane; loading a nanocrystalline drug on the microporous membrane; and fixing the microporous membrane loaded with the nanocrystalline drug to the device body.

Classes IPC  ?

• A61M 25/10 - Cathéters à ballon

Abrégé

The present application relates to a stent for a blood vessel. The stent comprises: a covering membrane (100) and an anchor piece (200) that are connected to one another; the anchor piece (200) is used to secure the covering membrane (100) in a blood vessel; and the covering membrane (100) is used to gather around a lesion site of the blood vessel. The anchor piece (200) of the stent is used to better attach the covering membrane (100) to a vascular intima and secure same at an expected implantation position when the stent is flushed by blood. The covering membrane (100) can gather around unstable plaque on the vascular intima, thus preventing the unstable plaque from rupturing. Meanwhile, the covering membrane (100) can also trigger a foreign matter reaction in the organism, thereby stimulating the growth of a vascular endothelium, enabling the unstable plaque to grow into stable plaque, and reducing the incidence of acute thrombus. In addition, the stent can also be used for the treatment of vascular tearing during intervention, so as to avoid a thrombosis event caused by a torn blood vessel wall shedding.

Classes IPC  ?

• A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents

Abrégé

A drug-loaded implanted medical device (10) and a preparation method therefor. The drug-loaded implanted medical device (10) comprises a device body (100), a hydrophilic coating layer (200) loaded on the device body (100), and crystalline drug particles (300) loaded on the hydrophilic coating layer (200). The hydrophilic coating layer (200) comprises a graft polymer containing a photo-crosslinked group. The medical device (10) uses a hydrophilic coating layer (200) as a carrier, effectively avoiding the risk of embolism, encouraging the crystalline drug particles to fall off, and helping to achieve a target tissue concentration. The invention can also effectively increase the anchoring effect between the carrier and the device, and reduce toxicity.

Classes IPC  ?

• A61L 31/10 - Matériaux macromoléculaires

Abrégé

The present application relates to a medical device. The medical device comprises a matrix and a first coating coated on the matrix. The matrix contains a metal element X having a content of ≥ 5 wt%; the first coating is at least one of an elemental metal layer of the metal element X, an alloy layer of the metal element X, and a metal-ceramic layer of the metal element X; and the first coating does not contain nickel and cobalt. The medical device has good use safety, reliability, and biocompatibility, so that a product can meet a use requirement of large plastic deformation, and has good reliability during use. The medical device can particularly meet requirements of products with large plastic deformation during use, such as medical implant devices.

Classes IPC  ?

• A61L 31/02 - Matériaux inorganiques
• A61L 31/08 - Matériaux de revêtement
• A61L 31/12 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
• C23C 14/00 - Revêtement par évaporation sous vide, pulvérisation cathodique ou implantation d'ions du matériau composant le revêtement
• C23C 28/00 - Revêtement pour obtenir au moins deux couches superposées, soit par des procédés non prévus dans un seul des groupes principaux , soit par des combinaisons de procédés prévus dans les sous-classes et
• C25D 3/04 - Dépôt électrochimiqueBains utilisés à partir de solutions de chrome
• C25D 3/50 - Dépôt électrochimiqueBains utilisés à partir de solutions de métaux du groupe du platine
• C25D 3/54 - Dépôt électrochimiqueBains utilisés à partir de solutions de métaux non prévus dans les groupes
• C25D 3/56 - Dépôt électrochimiqueBains utilisés à partir de solutions d'alliages
• C25D 9/04 - Revêtement électrolytique autrement qu'avec des métaux avec des matières inorganiques

Abrégé

Disclosed are a cationic nanodrug, a preparation method therefor, and a drug-loaded implantable medical device, wherein the cationic nanodrug comprises a vector and a drug loaded on the vector, and the vector comprises one or more of a cationic amphipathic compound and a cationic modifier; the cationic amphipathic compound is a cationic amphipathic compound containing amino and/or acyl; and the cationic modifier is a cationic modifier containing amino and/or acyl. The cationic nanodrug greatly improves the uptake of a drug by cells and has a good slow-release effect.

Classes IPC  ?

• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 31/10 - Matériaux macromoléculaires
• A61K 9/107 - Émulsions
• A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
• A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
• A61K 9/50 - Microcapsules

Abrégé

A drug-loaded medical instrument, including a medical instrument body and at least one drug coating. The drug coating is attached to at least one side of the surface of the medical instrument body, and the main components of the drug coating comprise a macrolide drug. The drug coating comprises a long prismatic crystal having three or more edges, and/or the drug coating comprises a crystal cluster formed by the long prismatic crystal having three or more edges, wherein the aspect ratio of the long prismatic crystal is (1-40): 1. The drug-loaded medical instrument can effectively improve the transfer speed of a drug to the blood vessel wall, and prolong the concentration of the drug in a tissue.

Classes IPC  ?

• A61M 25/10 - Cathéters à ballon
• A61M 25/00 - CathétersSondes creuses
• A61L 29/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 29/00 - Matériaux pour cathéters ou pour revêtement de cathéters

Abrégé

A proximal outer tube (1), a balloon catheter, and a stent system. The proximal outer tube (1) is at least divided into two sections along the axial direction; the distal end of the proximal outer tube (1) is a delivery wire (101); the proximal end of the proximal outer tube (1) is a single-lumen tube (103); and the delivery wire (101) is connected to the single-lumen tube (103). The balloon catheter comprises a single-lumen structure provided at the proximal end of the balloon catheter and a double-lumen structure provided at the distal end of the balloon catheter, wherein the single-lumen structure is connected to the double-lumen structure, and a balloon (3) is provided at the distal end of the double-lumen structure. The stent system comprises a stent and a balloon catheter, wherein the stent is loaded outside the balloon catheter. Since the proximal outer tube (1) is at least divided into two sections along the axial direction, the proximal outer tube (1) has different physical properties in the axial direction to improve the tracking performance and the pushing performance of the proximal outer tube (1), thus facilitating better control and pushing of the balloon catheter by a doctor during a surgery, so that the balloon catheter can reach a narrow bending diseased area along a guide wire.

Classes IPC  ?

• A61M 29/02 - Dilatateurs gonflablesDilatateurs faits de matériaux dilatables

Abrégé

A medical delivery device (20) and a drug delivery system, the drug delivery system comprising the medical delivery device (20), a dispersoid (40), a liquid dispersant (30) and a balloon catheter (10); the medical delivery device (20) comprises a first casing (21), a second casing (22), and a pushing mechanism, the first casing (21) being provided with a first storage chamber (23), and the second casing (22) being provided outside of the first casing (21) and being provided with a second storage chamber (24). When the medical delivery device (20) is in a first working state, the first storage chamber (23) is not in communication with the second storage chamber (24); when the medical delivery device (20) is in a second working state, the first storage chamber (23) communicates with the second storage chamber (24), so that the liquid dispersant (30) within the first storage chamber (23) enters the second storage chamber (24) and is mixed with the dispersoid (40) so as to form a dispersion system; and when the medical delivery device (20) is in a third working state, the pushing mechanism drives the first casing (21) to move relative to the second casing (22), so that the dispersion system flows to an external mechanism by means of a delivery port. The present system simplifies existing operation procedures for delivering dispersion systems, and also reduces the risk of contamination when the dispersion systems are configured outside of an instrument.

Classes IPC  ?

• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps

Abrégé

A degradable drug-loaded stent and a manufacturing method therefor. The degradable drug-loaded stent comprises a stent body, an outer surface of the stent body being provided with a drug-loaded groove, the stent body having a contracted state and an expanded state, the stent body being capable of switching from the contracted state to the expanded state via radial expansion, the stent body being a mesh columnar structure when in the expanded state, the depth of the drug-loaded groove being 10%-60% of the wall thickness of the mesh columnar structure.

Classes IPC  ?

• A61F 2/915 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles fabriquée à partir de feuilles perforées ou de tubes perforés, p. ex. perforés par découpe au laser ou gravés avec des bandes présentant une structure en méandre, des bandes adjacentes étant reliées l’une à l’autre
• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• B23K 26/38 - Enlèvement de matière par perçage ou découpage

Abrégé

Provided are an implantable medical device (100) and a method for manufacturing the same, and a method for manufacturing a stent. The implantable medical device (100) comprises a metal base (110) and a cladding layer (120). The cladding layer (120) is a nickel-free and cobalt-free metal layer which is deposited on the metal base (110) by means of a metal bond. The arrangement of the cladding layer (120) of the implantable medical device (100) on the metal base (110) can prevent carcinogenic elements in the metal base (110) such as nickel and cobalt from dissolution. Moreover, the cladding layer (120) is a nickel-free and cobalt-free metal layer, such that the implantable medical device (100) is free from problems of nickel or cobalt dissolution, thereby improving the biological safety of the implantable medical device (100).

Classes IPC  ?

• C23C 30/00 - Revêtement avec des matériaux métalliques, caractérisé uniquement par la composition du matériau métallique, c.-à-d. non caractérisé par le procédé de revêtement
• A61F 2/89 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles les éléments filiformes comprenant au moins deux anneaux adjacents reliés de manière flexible par des éléments séparés

Abrégé

Disclosed is a drug eluting balloon for a balloon catheter. The drug eluting balloon comprises a balloon body (100) and a coating (200), and the coating (200) comprises a water-soluble adhesive layer (210), an isolating layer (220) and a drug layer (230) from the inside out. After the drug eluting balloon is pushed to a diseased part, the balloon body (100) is expanded, and the water-soluble adhesive layer (210) dissolves due to scouring by a blood flow, such that the isolating layer (220) and the drug layer (230) are separated from an outer surface of the balloon body (100) and adhere to a blood vessel wall. The provision of the isolating layer (220) can effectively suppress the water-soluble adhesive layer (210) from removing part of the drug layer (230) during dissolution, and after the drug layer (230) adheres to and makes contact with the blood vessel wall, the isolating layer can also reduce the scouring effect on the drug layer (230) by the blood flow, thereby reducing the loss of drugs, allowing the drugs to be taken in by the blood vessel wall to the greatest extent, greatly improving the utilization rate of the drugs and improving the treatment effect while also preventing toxic and side effects brought about by large doses of the drugs. Moreover, the isolating layer (220) can also realize the slow release of the drug layer (230), such that the drug layer (230) can provide treatment for a long time, and a good treatment effect can be obtained.

Classes IPC  ?

• A61M 25/10 - Cathéters à ballon
• A61L 29/08 - Matériaux de revêtement
• A61L 29/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61M 25/00 - CathétersSondes creuses

Abrégé

The present invention relates to a drug-loaded medical device and a preparation method therefor, a drug balloon and a preparation method for a drug coating. The surface of the medical device or the drug balloon has a drug coating. The drug coating comprises a stabilizer and a drug. The stabilizer comprises a triblock amphiphilic polymer with hydrophilic segments at both ends, and the drug coating forms a suspension of nano-drug particles in a water-soluble environment. In this way, the prepared the prepared nano-drug coating is high in drug loading capacity and good in drug delivery effect, and particularly, after the nano-drug coating is in contact with water, the drug can be restored to the original nanoscale, the particle size is hardly increased, the embolism risk caused by particles is avoided, the safety of the device is improved, the drug intake is increased, and the therapeutic effect is improved.

Classes IPC  ?

• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
• A61M 25/10 - Cathéters à ballon
• A61L 29/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques

Abrégé

A stent is disclosed, which includes a stent body and a single-radiopaque component disposed at one or each of a proximal end and a distal end of the stent body. The stent body is composed of rings and struts, and one part of the single-radiopaque component is received in a receptacle of the stent body and another part of the single-radiopaque component protrudes out of a surface of the stent body. The area of the protruding part of the single-radiopaque component is larger than an area of the embedded part, the presence of the protruding part allowing the single-radiopaque component to appear wider and thicker in a radiologic image, enhancing the radiopacity of the stent during surgery.

Classes IPC  ?

• A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents
• A61F 2/89 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles les éléments filiformes comprenant au moins deux anneaux adjacents reliés de manière flexible par des éléments séparés

Abrégé

Provided are a drug-loaded implantable medical instrument and a manufacturing method therefor. The drug-loaded implantable medical instrument (10) comprises an instrument body (100), a microporous membrane (200) fixed on the instrument body (100), and a nanocrystal medicament (300) loaded on the microporous membrane (200).

Classes IPC  ?

• A61L 31/10 - Matériaux macromoléculaires
• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques

Abrégé

A rotator cuff balloon (10), comprising a limiting structure (100) and a protective structure (200) that is connected to the limiting structure (100); and the limiting structure (100) is provided with an arc along the coronal plane (102). The rotator cuff balloon (10) conforms to the physiological structure of the human shoulder joint, is limited to the subacromial space, and may reduce adverse events, such as foreign body sensation, dislocation and functional loss, from occurring to a patient. The protective structure (200) is used to support within the gap between the humeral head and the acromion of the human shoulder joint to achieve a supporting effect. Meanwhile, the humeral head of a patient suffering from a rotator cuff injury moves upward, thus preventing pain caused by impact between tissues and also adding a deltoid muscle force applying force arm in order to immediately improve the function of the shoulder joint of the patient. In addition, the limiting structure (100) is used to at least partially fit the humeral head of the human shoulder joint so as to have a limiting effect, and avoid prosthesis displacement.

Classes IPC  ?

• A61F 2/08 - MusclesTendonsLigaments
• A61F 2/40 - Articulations pour les épaules

Abrégé

An embolic protection device, comprising an embolic deflector (100) and a push tube (300). The embolic deflector (100) comprises a first support frame (110) and a first filter element (120) disposed on the first support frame (110); and the push tube (300) comprises a tube body (310), which is connected to the embolic deflector (100) and is used for pushing, positioning and adjusting the embolic deflector (100). The described embolic deflector (100) that protects upstream blood vessels has excellent wall adhesion performance by virtue of the push tube (300). The tube body (310) further comprises a hypo cutting structure provided at a distal end thereof so that the push tube (300) is shaped by an internal guide wire, thus adapting to the anatomical structure of the aortic arch of a patient so that the embolic deflector (100) has better wall adhesion performance.

Classes IPC  ?

• A61F 2/01 - Filtres implantables dans les vaisseaux sanguins
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

Abrégé

A drug-loaded implanted medical device (10) and a preparation method therefor. The drug-loaded implanted medical device (10) comprises a device body (100), a hydrophilic coating layer (200) loaded on the device body (100), and crystalline drug particles (300) loaded on the hydrophilic coating layer (200). The hydrophilic coating layer (200) comprises a graft polymer containing a photo-crosslinked group. The medical device (10) uses a hydrophilic coating layer (200) as a carrier, effectively avoiding the risk of embolism, encouraging the crystalline drug particles to fall off, and helping to achieve a target tissue concentration. The invention can also effectively increase the anchoring effect between the carrier and the device, and reduce toxicity.

Classes IPC  ?

• A61L 31/00 - Matériaux pour autres articles chirurgicaux
• A61L 31/04 - Matériaux macromoléculaires
• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau

Abrégé

Disclosed are a hemostatic clip and an auxiliary system. The hemostatic clip comprises a first clip piece (110), a second clip piece (120), a tightening tube (140), a middle clip piece (150), a middle shaft assembly (160), a traction assembly (170), a control handle (180) and at least two separation members (190), wherein the traction assembly (170) is respectively connected to the control handle (180) and the middle shaft assembly (160); the middle shaft assembly (160) is connected to the tightening tube (140); the proximal end of the first clip piece (110) and the proximal end of the second clip piece (120) are connected to the traction assembly (170); the proximal end of the middle clip piece (150) penetrates the tightening tube (140) to be fixedly connected to the middle shaft assembly (160); the first clip piece (110) and the second clip piece (120) are arranged on two sides of the middle clip piece (150); the first clip piece (110) and the middle clip piece (150) form a first clip body; the second clip piece (120) and the middle clip piece (150) form a second clip body; the control handle (180) is used for opening or closing the first clip body and the second clip body corresponding to the first clip piece (110) and/or the second clip piece (120); and the separation members (190) are arranged in a tube cavity of the tightening tube (140), and are located between the first clip piece (110) and the middle clip piece (150) and between the second clip piece (120) and the middle clip piece (150), such that the instrument fault risk caused by the interference of the first clip piece (110), the second clip piece (120) and the middle clip piece (150) is reduced.

Classes IPC  ?

• A61B 17/122 - Clamps ou pinces, p. ex. pour le cordon ombilical
• A61B 17/128 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical pour appliquer ou enlever les clamps ou les pinces

Abrégé

A medical instrument (1000), comprising a stent (100) and a constraint device (300), the constraint device (300) being used to constrain the tail portion of the stent (100), thus avoiding tangling of the tail portion of the stent (100), and finally ensuring successful release of the stent (100). Specifically, the stent (100) has a first proximal end and a first distal end opposite to each other, the first distal end is configured to have a deployed state and a converged state, and the tail portion of the first distal end comprises several protrusions (111). The constraint device (300) comprises a main body (310) and a clamping mechanism (320), the clamping mechanism (320) is provided at the distal end of the main body (310), the main body (310) extends through the first proximal end to the first distal end, and the clamping mechanism (320) passes through all or a part of the protrusions (111) to limit relative movement between the protrusions (111), thereby avoiding tangling between the protrusions (111), and reducing the deformation of the stent (100) in a delivery sheath, thereby enabling the stent (100) to smoothly deploy after being separated from the sheath.

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
• A61F 2/24 - Valvules de cœur

Abrégé

A drive shaft (1, 3) for a rotation device (10, 20) comprises an outer layer (11, 31) and an inner layer (12, 32). The outer layer is a tubular structure. The inner layer is disposed in an accommodation space formed by the outer layer, and has a central cavity (13, 33) used to receive an external mechanism therein. The outer layer rotates about the central cavity, and the inner layer rolls relative to the outer layer and the external mechanism, such that rolling friction is formed between the drive shaft and the external mechanism by the inner layer. The structure of the drive shaft is capable of reducing a friction force and friction loss between the drive shaft and a guide wire, and prevents the problem of a guide wire failure caused by excessive friction between a guide wire and the drive shaft, thereby ensuring that the drive shaft matches common clinical guide wires, improving operability of surgical procedures, and reducing surgical costs. Further provided is a rotation device, comprising a tool (2, 4) and the drive shaft. The tool is disposed at one end of the drive shaft and connected to the outer layer of the drive shaft, and performs a rotating movement when driven by the outer layer.

Classes IPC  ?

• A61B 17/3207 - Dispositifs d'athérectomie

Abrégé

Disclosed are a cationic nanodrug, a preparation method therefor, and a drug-loaded implantable medical device, wherein the cationic nanodrug comprises a vector and a drug loaded on the vector, and the vector comprises one or more of a cationic amphipathic compound and a cationic modifier; the cationic amphipathic compound is a cationic amphipathic compound containing amino and/or acyl; and the cationic modifier is a cationic modifier containing amino and/or acyl. The cationic nanodrug greatly improves the uptake of a drug by cells and has a good slow-release effect.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61L 31/10 - Matériaux macromoléculaires
• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 31/08 - Matériaux de revêtement
• A61L 31/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps

Abrégé

A rotary grinding device, comprising a driving shaft (2) and a rotary grinding assembly (1) connected to the driving shaft (2), wherein the rotary grinding assembly (1) comprises a base (11) and a rotary grinding block (12), the rotary grinding block (12) can be assembled on the base (11) in a relatively movable mode, and when the rotary grinding assembly (1) rotates, the rotary grinding block (12) moves towards a direction away from the base (11). By means of a rotary grinding head consisting of the rotary grinding assembly (1), the external size of the rotary grinding head in a stationary state is reduced, so that the rotary grinding head can well reach a lesion through a blood vessel; and by changing the movement radius of the rotary grinding head and the size of the opening lesion by means of centrifugal force generated under high-speed rotation, the purpose of automatically adjusting the grinding hole size can be achieved, so that the frequency of constant replacement of the rotary grinding head during use is reduced.

Classes IPC  ?

• A61B 17/3207 - Dispositifs d'athérectomie

Abrégé

A degradable drug-loaded stent and a manufacturing method therefor. The degradable drug-loaded stent comprises a stent body (10), an outer surface of the stent body being provided with a drug-loaded groove (13), the stent body having a contracted state and an expanded state, the stent body being capable of switching from the contracted state to the expanded state via radial expansion, the stent body being a mesh columnar structure when in the expanded state, the depth of the drug-loaded groove (13) being 10%-60% of the wall thickness of the mesh columnar structure.

Classes IPC  ?

• A61F 2/90 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles

Produits et services

(1) Medical apparatus and instruments; stents; medical guidewires; catheters; balloon catheters; needles for medical purposes; electrodes for medical use; surgical implants comprised of artificial materials; artificial cardiac valves; suture materials

Produits et services

Medical apparatus and instruments; stents; catheters; medical guidewires; trocars; electrodes for medical use; gloves for medical purposes; surgical implants comprised of artificial materials; orthopaedic articles; suture materials.

Produits et services

Catheters; medical apparatus and instruments; trocars; medical guidewires; stents; electrodes for medical use; gloves for medical purposes; surgical implants comprised of artificial materials; orthopaedic articles; suture materials.

Produits et services

Medical apparatus and instruments; catheters; hearing protectors; X-ray apparatus for medical purposes; breast pumps; surgical implants comprised of artificial materials; orthopaedic articles; contraceptives, non-chemical; thread, surgical; dental apparatus, electric.

Produits et services

Catheters; surgical apparatus and instruments; pumps for medical purposes; medical apparatus and instruments; cases fitted for medical instruments; operating tables; surgical implants comprised of artificial materials; stents; medical guidewires; tubing for use with catheters.

Abrégé

Provided is a bio-coating (100), comprising a surface layer (110), wherein the surface layer (110) comprises multiple first single bodies connected in an unordered manner, and multiple first through holes are formed between the multiple first single bodies and inside the multiple first single bodies. The surface layer (110) is arranged on the outermost side of the bio-coating (100), the surface layer (110) comprises the multiple first single bodies, which are connected in an unordered manner, and the multiple first through holes are formed between the multiple first single bodies and inside the multiple first single bodies, i.e., the multiple first single bodies in the surface layer (110) are connected in an unordered manner; therefore, the multiple first through holes in the surface layer (110) can be in an unordered state, thereby facilitating the growing of corresponding bone tissue cells into the surface layer (110), and thus improving a bone ingrowth effect and long-term stability.

Classes IPC  ?

• A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents

Abrégé

Provided are a balloon (100), a balloon connecting structure (200) and a balloon device. The balloon connecting structure (200) is used for being detachably connected to the balloon (100), the balloon connecting structure (200) comprises an outer catheter (220) and an inner catheter (210), wherein one end of the outer catheter (220) is used for being connected to the outside of a self-closing structure (110), and when the outer catheter (220) is subjected to a first external force, the outer catheter (220) can be separated from the self-closing structure (110); one end of the inner catheter (210) is used for being connected to the inside of the self-closing structure (110), and when the inner catheter (210) is subjected to a second external force, the inner catheter (210) can be separated from the self-closing structure (110); through the action of the first external force and the second external force, after the balloon (100) reaches a stomach, the balloon connecting structure (200) can be conveniently separated from the balloon (100); and when the outer catheter (220) or the inner catheter (210) is in a state separated from the self-closing structure (110), the inner catheter (210) is movably arranged in the outer catheter (220) in a penetrating manner. Preferably, after the balloon connecting structure (200) is separated from the balloon (100), the balloon connecting structure and the balloon can be connected together again when necessary in order to facilitate adjusting the volume of the balloon (100).

Classes IPC  ?

• A61M 25/10 - Cathéters à ballon

Abrégé

A porous balloon and a preparation method therefor; the porous balloon is used for drug loading, and he porous balloon is prepared by employing the following method: soaking an interventional carrier in an etching solution for etching so as to obtain a porous balloon (S3). The structure of the porous balloon is suitable for the storage and release of a drug, improves the binding force between a drug coating and a surface of the porous balloon, and solves the problems wherein a drug coating easily falls off a surface of a balloon during pushing and retraction, a drug is not sufficiently evenly covered on a surface, and the drug release rate and release speed are not high enough during release; in addition, the structure of the porous balloon does not reduce the physical properties of the balloon, avoiding the problem wherein etching grooves results in balloon properties, especially physical properties, being reduced, such as balloon rated burst pressure being reduced.

Classes IPC  ?

• A61M 25/10 - Cathéters à ballon
• A61L 29/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61L 29/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques

Produits et services

Catheters; Trocars; Balloon catheters; Inflation devices for balloon catheters; Medical apparatus and instruments; Medical guidewires; Medical stents; Gloves for medical purposes; Containers especially adapted for the disposal of medical instruments, syringes and other contaminated medical waste; Suture materials.

Abrégé

Disclosed is a drug eluting balloon for a balloon catheter. The drug eluting balloon comprises a balloon body (100) and a coating (200), and the coating (200) comprises a water-soluble adhesive layer (210), an isolating layer (220) and a drug layer (230) from the inside out. After the drug eluting balloon is pushed to a diseased part, the balloon body (100) is expanded, and the water-soluble adhesive layer (210) dissolves due to scouring by a blood flow, such that the isolating layer (220) and the drug layer (230) are separated from an outer surface of the balloon body (100) and adhere to a blood vessel wall. The provision of the isolating layer (220) can effectively suppress the water-soluble adhesive layer (210) from removing part of the drug layer (230) during dissolution, and after the drug layer (230) adheres to and makes contact with the blood vessel wall, the isolating layer can also reduce the scouring effect on the drug layer (230) by the blood flow, thereby reducing the loss of drugs, allowing the drugs to be taken in by the blood vessel wall to the greatest extent, greatly improving the utilization rate of the drugs and improving the treatment effect while also preventing toxic and side effects brought about by large doses of the drugs. Moreover, the isolating layer (220) can also realize the slow release of the drug layer (230), such that the drug layer (230) can provide treatment for a long time, and a good treatment effect can be obtained.

Classes IPC  ?

• A61M 25/10 - Cathéters à ballon

Produits et services

Catheters; Trocars; Balloon catheters; Inflation devices for balloon catheters; Medical apparatus and instruments; Medical guidewires; Medical stents; Gloves for medical purposes; Containers especially adapted for the disposal of medical instruments, syringes and other contaminated medical waste; Suture materials.

Produits et services

Catheters; Trocars; Balloon catheters; Inflation devices for balloon catheters; Medical apparatus and instruments; Medical guidewires; Medical stents; Gloves for medical purposes; Containers especially adapted for the disposal of medical instruments, syringes and other contaminated medical waste; Suture materials.

Abrégé

A left atrial appendage occluder (100) and a left atrial appendage occlusion system. The occluder (100) may better achieve repeated positioning, recovery and release of the left atrial appendage occluder (100), and may prevent the problem wherein an occlusion stent (110, 10) is entangled during operation, thereby improving the success rate of surgery. The left atrial appendage occluder (100) comprises an occlusion stent (110, 10), a proximal end fixing member (120) and a distal end fixing member (130); the occlusion stent (110, 10) comprises an occlusion structure (111) and a traction structure (112). A delivery device (200) comprises a pushing hollow tube (210) and a control rod (220). The distal end fixing member (130) may, under the drive of the control rod (220), move toward a first distal end (111b) of the occlusion structure (111) toward the direction of the proximal end fixing member (120) to be in a gathered state, and may prevent the continuous movement of the distal end fixing member (130), thus preventing the problem wherein misoperation by a human causes the occlusion stent (110, 10) to become inverted and entangled.

Classes IPC  ?

• A61F 2/02 - Prothèses implantables dans le corps

Produits et services

Medical apparatus and instruments for use in cardiovascular, angioplasty, and endovascular procedures; medical apparatus, namely, stents for unclogging arterial occlusion; catheters

Abrégé

A stent is disclosed, which includes a stent body (2) and a single-radiopaque component (1) disposed at one or each of a proximal end and a distal end of the stent body (2). The stent body (2) is composed of rings and struts, and one part of the single-radiopaque component (1) is received in a receptacle (3) of the stent body (2) and another part of the single-radiopaque component (1) protrudes out of a surface of the stent body (2). The area of the protruding part (11) of the single-radiopaque component (1) is larger than an area of the embedded part (10), the presence of the protruding part (11) allowing the single-radiopaque component (1) to appear wider and thicker in a radiologic image, enhancing the radiopacity of the stent during surgery.

Classes IPC  ?

• A61F 2/86 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles

Abrégé

Provided are the uses of a specific antibody, an implantable medical instrument, and a preparation method therefor. The uses are those of a specific antibody of an ATP-binding cassette transporter in preparing a drug for promoting endothelial repair. The presenthe surface of the implantable medical instrument is loaded with the specific antibody of the ATP-binding cassette transporter. The preparation method comprises loading the specific antibody of the ATP-binding cassette transporter on at least a part of the surface of the implantable medical instrument; and/or binding the specific loaded antibody of the ATP-binding cassette transporter into the hole or the groove of the implantable medical instrument.

Classes IPC  ?

• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61F 2/06 - Vaisseaux sanguins
• A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
• A61L 31/08 - Matériaux de revêtement

Abrégé

Provided are the uses of a specific antibody, an implantable medical instrument, and a preparation method therefor. The uses are those of a specific antibody of a hematopoietic stem cell marker in preparing a drug for promoting endothelial repair. The surface of the implantable medical instrument is loaded with the specific antibody of hematopoietic stem cell marker. The preparation method comprises loading the specific antibody of the hematopoietic stem cell marker on at least a part of the surface of the implantable medical instrument; and/or binding the specific loaded antibody of the hematopoietic stem cell marker into the hole or the groove of the implantable medical instrument.

Classes IPC  ?

• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61F 2/06 - Vaisseaux sanguins
• A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
• A61L 31/08 - Matériaux de revêtement

Produits et services

Catheters; trocars; medical guidewires; stents; medical electrodes; medical gloves; surgical implants comprised of artificial materials; suture materials

Abrégé

A medical device and a preparation method therefor, which may effectively mold a protrusion (11, 21, 31) on a balloon structure (10, 20, 30) without affecting the usage performance of the balloon structure (10, 20, 30), and improve the anti-offload capabilities of a support (100) so as to prevent the support (100) from disengaging from the balloon structure (10, 20, 30) during a pushing process, thus reducing the damage to a blood vessel wall during the pushing process, and preventing an end portion of the support (100) from forking as well as preventing a bell mouth effect caused by forking. The preparation method for a medical device comprises: providing an initial structure (101) of a balloon structure (10, 20, 30) in a folded state; pressing a support (100) onto the initial structure (101); mounting a pretreatment mold (410, 510, 610, 710) on the initial structure (101) on which the support (100) is pressed such that the initial structure (101) on which the bracket (100) is pressed is accommodated in a molding cavity (511, 716) of the the pretreatment mold (410, 510, 610, 710); enabling the initial structure (101) to be heated in the molding cavity (511, 716) and be infused with a fluid so that the initial structure (101) forms a protrusion in the molding cavity (511, 716) and is shaped to obtain a molding structure of the balloon structure (10, 20, 30).

Classes IPC  ?

• A61F 2/958 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes ballons gonflables pour insérer les stents ou les endoprothèses déployables couvertes

Abrégé

A support structure, a prosthesis, and a prosthesis system, to enhance the support strength of a prosthesis and ensure a stable and effective extension function of the prosthesis. The support structure comprises an extending member (21) and a blocking member (22). The extending member (21) comprises a body and a plurality of brim structures (2114) at a proximal end of the body. The plurality of brim structures (2114) extend outwards in a radial direction of the body into a limiting member (1), and the plurality of brim structures (2114) are also arranged in an axial direction of the body. The body has an inner cavity (2112) closed at one end, and the body is provided with a hollow structure (2113) at a position adjacent to the plurality of brim structures (2114). The blocking member (22) is a hollow structure open at both ends and is disposed in the inner cavity (2112) to cover the hollow structure (2113). When the plurality of brim structures (2114) generate heat, part of the limiting member (1) in contact with the plurality of brim structures (2114) softens, so as to eliminate the limiting of the limiting member (1) on the support structure.

Classes IPC  ?

• A61F 2/28 - Os

Abrégé

An occlusion device (8) and a preparation method therefor. The occlusion device (8) comprises a skeleton and flow blocking membranes (3, 4), the skeleton comprises a waist (1) and barbs (2, 5) that are connected to at least one end of the waist (1), the flow blocking membranes (3, 4) are fixed on at least one end of the waist (1) and/or an inner side of the barbs (2, 5), a cavity is formed between the skeleton and the flow blocking membranes (3, 4), and an injection orifice (6) is provided on the skeleton or the flow blocking membranes (3, 4). The structure of the occlusion device (8) makes the dimension of the occlusion device smaller, so that the occlusion device can be used in a delivery sheath having a smaller diameter, the damage to the blood vessel wall is less, and is also suitable for the interventional occlusion for the younger age group, meanwhile, the material usage is reduced, the rate of complications after implantation is decreased, and cost is saved. The degradable hydrogel used can fill irregularly shaped tissue defects, can be applied to cases where the edge of a defect site is narrow and the shape of a defect site is complicated, and widen the application range of the interventional therapy for cardiac septal defects.

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical

Abrégé

An occlusion device and a preparation method therefor. The occlusion device comprises a skeleton and flow blocking membranes (3, 4), the skeleton comprises a waist (1) and barbs (2, 5) that are connected to at least one end of the waist (1), the waist (1) is coated with a solid xerogel, and the flow blocking membranes (3, 4) are fixed on at least one end of the waist (1) and/or an inner side of the barbs (2, 5). The structure of the occlusion device makes the dimension of the occlusion device smaller, so that the occlusion device can be used in a delivery sheath having a smaller diameter, the material usage is reduced, the rate of complications after implantation is decreased, and cost is saved. By means of the expansion characteristics of the solid xerogel after contacting with blood, the solid xerogel can fill irregularly shaped tissue defects, can be applied to cases where the edge of a defect site is narrow and the shape of a defect site is complicated, and widen the application range of the interventional therapy for cardiac septal defects.

Classes IPC  ?

• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

Abrégé

The present invention provides an occluder and a medical device. The occluder comprises: an occluding unit having a remote end and a near end; and a position-limiting unit connected to the remote end and the near end for limiting an extension distance therebetween. The position-limiting unit is connected to the remote end and the near end of the occluding unit to limit the extension distance therebetween, such that the occluder is in an entirely or partially collapsed state when in a sheath, thereby preventing the issue of the occluder occupying an excessive length of the sheath. The occluder is not fully extended while in the sheath, but instead remains in an entirely or partially collapsed state, so as to better maintain the dimensions of the occluder after the same is released from the sheath.

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical

Abrégé

The present invention provides a protection device for a stent and a medical device. The protection device for a stent mainly comprises a sheath, a first handle and a second handle, the sheath being used for accommodating the stent, the first handle being able to get close to the second handle and drive a first portion of the sheath to be separated from a second portion of the sheath, so that the stent is removed from the sheath. The protection device for a stent of the present invention can realize, only by means of a one-handed operation, the process of the first handle getting close to the second handle and driving the first portion of the sheath to be separated from the second portion, simplifying the operation process, and improving the working efficiency.

Classes IPC  ?

• A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents

Abrégé

A drug-loaded implanted medical device and a preparation method therefor. The drug-loaded implanted medical device comprises a device body and grooves (2) distributed on the surface of the device body, and at least one of the grooves (2) is loaded with a solid drug (11); the solid drug (11) is a crystal or has a form in which a crystal coexists with an amorphous body. The preparation method is implemented by loading the solid drug (11) into at least one of the grooves (2) by means of solution crystallization.

Classes IPC  ?

• A61L 31/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques

Abrégé

Disclosed are a left atrial appendage occlusion device (100, 300) and a left atrial appendage occlusion system. A connecting member (140, 240, 340, 440) comprises a first unit (140a, 240a, 440a) and a second unit (140b, 240b, 440b), wherein the first unit (140a, 240a, 440a) is connected to a first frame (110, 310, 410), the second unit (140b, 240b, 440b) is connected to a second frame (120, 320, 420), and the first unit (140a, 240a, 440a) is rotatably connected to the second unit (140b, 240b, 440b). Alternatively, the connecting member (140, 240, 340, 440) comprises the first unit (140a, 240a, 440a), the second unit (140b, 240b, 440b) and a third unit (140c, 240c), wherein the first unit (140a, 240a, 440a) is connected to the first frame (110, 310, 410), the second unit (140b, 240b, 440b) is connected to the second frame (120, 320, 420), the first unit (140a, 240a, 440a) is rotatably connected to the third unit (140c, 240c), and the second unit (140b, 240b, 440b) is rotatably connected to the third unit (140c, 240c). Thereby, with regard to left atrial appendages having lumens of different shapes, the relative positions of the first frame (110, 310, 410) and the second frame (120, 320, 420) can be changed by means of the connecting member (140, 240, 340, 440), i.e., the shape of the left atrial appendage occlusion device (100, 300) is adjusted so as to be capable of being adapted to left atrial appendages having lumens of different shapes.

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical

Abrégé

Disclosed are a left atrial appendage occluder (100) and a left atrial appendage occlusion device (200). The left atrial appendage occluder (100) comprises: an occlusion structure (110) and a guide structure (120), wherein the guide structure (120) is used for positioning a pushing structure (130) for the occlusion structure (110); and the guide structure (120) is located in the occlusion structure (110) and can be drawn out from the occlusion structure (110), and a proximal end of the guide structure (120) is exposed from a proximal end of the occlusion structure (110). When the pushing structure (130) needs to be re-connected to the occlusion structure (110) after the pushing structure (130) is separated from the occlusion structure (110), the guide structure (120) can guide the pushing structure (130), such that the pushing structure (130) can be easily re-connected to the occlusion structure (110), thus performing re-positioning.

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
• A61F 2/06 - Vaisseaux sanguins

Abrégé

A cryoablation balloon (1, 2), which has an outer layer that is made from a fluorine-containing polymer, wherein the cryoablation balloon (1, 2) may be of a single-layer or a double-layer structure. The cryoablation balloon (1, 2) will not rupture at even a temperature below -40℃, and the balloon may also fulfill a retraction function and a high pressure-tolerance function and is less difficult to process. Also disclosed is a cryoablation medical device.

Classes IPC  ?

• A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques

Abrégé

A prosthesis, comprising a housing (10), a first sleeve (31), a second sleeve (32) and a third sleeve (33) that are accommodated within the housing (10); the second sleeve (32) is configured to remain axially stationary relative to the housing (10), the second sleeve (32) being coaxially sleeved on an exterior portion of the first sleeve (31); the first sleeve (31) is connected to the third sleeve (33) by means of a restriction assembly, and the third sleeve (33) extends from a proximal end to a distal end, and extends out of the housing (10), the restriction assembly restricting the third sleeve (33) from rotating about an axis of the second sleeve (32). Under the action of an alternating magnetic field, the second sleeve (32) has a first working state and a second working state; when the second sleeve (32) is in the first working state, the second sleeve (32) drives the first sleeve (31) to move along an axial direction of the housing (10), and when the second sleeve (32) is in the second working state, the second sleeve (32) causes the first sleeve (31) remain axially stationary relative to the second sleeve (32).

Classes IPC  ?

• A61F 2/30 - Articulations
• A61F 2/36 - Têtes fémorales
• A61F 2/62 - Jambes ou pieds artificiels ou leurs parties réglables, p. ex. tibias, cuisses ou systèmes squelettiques tubulaires réglables

Abrégé

A medical apparatus (10 and 20), which comprises a left atrial appendage occluder (1 and 4), a support frame transport element (31 and 61), a fixed part (2 and 5), and a fixed transport element (32 and 62). The support frame transport element (31 and 61) are provided with a first channel and a first connecting extremity provided at the distal extremity of the first channel. The left atrial appendage occluder (1 and 4) comprises a support frame body (11 and 41) and a support frame connecting element (12 and 42) provided on the support frame body (11 and 41). The support frame connecting element (12 and 42) is provided with a second channel and a second connecting extremity provided on the second channel. The first and second connecting extremities can be joined so as to allow the first and second channels to communicate and form a pushing channel. The distal extremity of the fixed transport element (32 and 62) can be joined with the fixed part (2 and 5) so as to allow the fixed transport element (32 and 62) to push in the pushing channel the fixed part (2 and 5) to enter a preset area, thus connecting the left atrial appendage occluder (1 and 4) to the preset area. The medical apparatus (10 and 20) facilitates the left atrial appendage occluder (1 and 4) to easily implement repeated positioning and retraction, neither damages a sheath nor experiences the problem of positioning failure caused by anchor detachment as a result of coming into contact with the sheath, thus improving the safeness of a surgery.

Classes IPC  ?

• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

Produits et services

Medical apparatus and instruments; stents; catheters; suture materials; balloon catheters (medical apparatus); Medical and surgical catheters; catheters for drug injection; medical suturing device especially for wound; medical suturing device; Catheters for medical use.

Produits et services

Medical apparatus and instruments; stents; catheters; suture materials; balloon catheters (medical apparatus); Medical and surgical catheters; catheters for drug injection; medical suturing device especially for wound; medical suturing device; Catheters for medical use.

Abrégé

A stent. The stent comprises a stent body (2) and a single development component (1) located at the near end and/or the distant end of the stent body (2). The stent body (2) consists of a connecting ring and a connecting rod. One part of the single development component (1) is embedded in a mounting hole (3) of the stent body (2), another part of the single development component (1) protrudes from the surface of the stent body (2), and the area of the protruding part (11) of the single development component (1) is greater than that of the embedded part (10). The protruding part (11) increases the development area and the height of the single development component (1), and the developing effect of the stent in an operation is improved.

Classes IPC  ?

• A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents

Abrégé

Disclosed is use of amlexanox or a salt thereof or a solvate thereof in preparation of a drug having an inhibitory action on the smooth muscle cells, in particular a drug for preventing and treating vascular restenosis. Further disclosed is a medical device, particularly a drug stent, the surface of which is distributed with amlexanox or the salt thereof or the pharmaceutical composition thereof. Amlexanox has an activity in inhibition of the proliferation of smooth muscle cells, has a low inhibitory property of the endothelial cell growth, is particularly suitable for applying on a medical device to prevent the incidence of vascular restenosis, while not delaying the repair of endothelium.

Classes IPC  ?

• A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
• A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 29/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques

Abrégé

A restriction apparatus, which is used for restricting a stent (1); the stent (1) is fixed to the outside of a support (2), characterized in that the restriction apparatus comprises an expandable body (3) provided on the outside of the stent (1); the expandable body (3) has a first dimension in a first state for restricting the expansion of the stent (1), the expandable body (3) has a second dimension in a second state, and the second dimension is larger than the first dimension. The restriction apparatus is able to effectively restrict an overall size of the stent (1), and prevent a radial expansion of the stent (1) from occurring following the removal of a compression apparatus prior to entering a human body. Further provided are a stent system and a method for using the restriction apparatus.

Classes IPC  ?

• A61F 2/962 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes possédant une gaine extérieure
• A61M 25/10 - Cathéters à ballon

Abrégé

Disclosed are a left auricle occluder (1) and a delivery device (6). The left auricle occluder (1) comprises a plurality of brace beams (11), wherein the brace beams (11) are distributed over the outer side of a first hub (10) and extends outward, the brace beam (11) branches into a left brace beam (111) and a right brace beam (112) at a first location (110), the left brace beam (111) and the right brace beam (112) of adjacent brace beams (11) are connected at a second location (113) and extend distally to form a distal end, and a brace rod (12) is provided between adjacent brace beams (11), so as to ensure the stability of the left auricle occluder (1) and prevent same from being irregularly deformed or sliding laterally. With the brace rods (12) between the adjacent support beams (11), the left auricle occluder (1) forms a dense mesh, thus further improving the overall strength of the left auricle occluder (1).

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical

Produits et services

(1) Stents; catheters; medical guidewires; trocars; electrodes for medical use; gloves for medical purposes; surgical implants comprised of artificial materials; orthopaedic articles, namely, stents, soles, footwear, belts, insoles, knee bandages, inserts for footwear and hip prostheses; suture materials.

Abrégé

An alloy material and an implantable medical device utilizing the alloy material. The elemental composition of the material by weight percentage is: less than 3% magnesium; 0.001% to 0.5% selenium; 0.001 to 0.5% strontium; and the remainder being zinc.

Classes IPC  ?

• C22C 18/00 - Alliages à base de zinc

Abrégé

Disclosed are a bone plate and a manufacturing method thereof. The bone plate comprises a framework (1), wherein the framework (1) is of a three-dimensional structure formed of weaving yarns. The provided bone plate uses the framework (1) which is integrally formed by a three-dimensional fabric; since the three-dimensional fabric has yarns for connection in the thickness direction, the mechanical property of the bone plate in the thickness direction can be enhanced, the strength in every direction is much better than that of non-textile-reinforced or fibre-reinforced materials, consequently, the strength of the bone plate can be effectively increased, and the modulus of the bone plate can be decreased; moreover, the structure is simple, and the bone plate can gradually degrade after being implanted, and therefore does not need to be taken out by operating again.

Classes IPC  ?

• A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone

Abrégé

Provided is a medical device for treating cardiac arrhythmia, comprising: a microprocessor (8) and a digital/analog module (9); a main control unit (1) sets a medical device to a DVI(R) operating mode: a signal of a sensing control/amplification unit (6) sensing an atrial event is received, then the main control unit (1) sets a PANP interval and sends a signal to a time control unit (2) and controls a first timing unit (11) to enter a timing mode, the duration being a PANP interval; if the anticipated ventricular pacing escape interval overflow occurs outside the PANP interval, then the main control unit (1) sends, to a pacing control/generation unit (5) and the time control unit (2), a signal to notify the pacing control/generation unit (5) to issue a pacing pulse, and controls a second timing unit (12) to set the subsequent atrioventricular interval to be the next ventricular pacing escape interval; if the anticipated post-ventricular pacing escape-interval overflow occurs within the PANP interval, then the main control unit (1) sends a signal to the time control unit (2), and controls the second timing unit (12) to set the subsequent atrioventricular interval to be the next ventricular pacing escape interval.

Classes IPC  ?

• A61N 1/362 - Stimulateurs cardiaques
• A61N 1/39 - Défibrillateurs cardiaques

Abrégé

Provided is a medical device for treating cardiac arrhythmia, comprising: a microprocessor (8) and a digital/analog module (9); a main control unit (1) sets a device to a DDD(R) operating mode: within a PVARP, a message of a sensing control/amplification unit (6) sensing an atrial event is received, then the main control unit (1) sets a PANP interval and sends a signal to a time control unit (2) and controls a first timing unit (11) to enter a timing mode, the duration being a PANP interval; if the post-ventricular pacing escape-interval overflow occurs within the PANP interval, then the main control unit (1) sends a signal to the time control unit (2), and controls the second timing unit (12) to set the atrioventricular interval to be the next ventricular pacing escape interval; if the post-ventricular pacing escape-interval overflow occurs outside the PANP interval, then the main control unit (1) sends, to a pacing control/generation unit (5) and the time control unit (2), a signal to notify the pacing control/generation unit (5) to issue a pacing pulse, and controls the second timing unit (12) to set the atrioventricular interval to be the next ventricular pacing escape interval.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques

Abrégé

Provided is a medical device for treating cardiac arrhythmia, comprising: a microprocessor (8) and a digital/analog module (9); the microprocessor (8) comprises a main control unit (1) and a time control unit (2); the digital/analog module (9) comprises a pacing control/generation unit (5) and a sensing control/amplification unit (6); the time control unit (2) comprises a first timing unit (11) and a second timing unit (12); the main control unit (1) sets a medical device to an ADI(R) operating mode, the ADI(R) operating mode comprising: a signal of a sensing control/amplification unit (6) sensing a ventricular event is received, then the main control unit (1) sets a PVANP interval and sends a signal to a time control unit (2), and controls a first timing unit (11) to enter a timing mode, the duration being a PVANP interval; if the anticipated atrial pacing escape occurs outside the PVANP interval, then the main control unit (1) sends to the pacing control/generation unit (5) and the time control unit (2) a signal to notify the pacing control/generation unit (5) to issue a pacing pulse, and controls the second timing unit (12) to set the subsequent atrial pacing escape interval; if the anticipated atrial pacing escape occurs within the PVANP interval, then the main control unit (1) sends a signal to the time control unit (2), and controls the second timing unit (12) to set the subsequent atrial pacing escape interval.

Classes IPC  ?

• A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
• A61N 1/39 - Défibrillateurs cardiaques

Produits et services

Medical apparatus and instruments; stents for medical purpose; catheters for medical purpose; medical guidewires; trocars; electrodes for medical use; gloves for medical purposes; surgical implants [artificial materials]; orthopaedic articles; suture materials.

Abrégé

Disclosed are a cardiac pacemaker system and a control method thereof. A logic and time series portion of a pacing function is provided by firmware of a microprocessor (100), and a perception and pulse firing function is provided by a peripheral integrated circuit (200). The microprocessor (100) and the peripheral integrated circuit (200) are in communication with each other through a serial interface (5, 11) and an electric level signal. Accordingly, internal resources of the modern ultralow power consumption microprocessor (100) are fully used, the dependence of the cardiac pacemaker system on the peripheral integrated circuit (200) is reduced, and the design workload of a digital circuit is reduced.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques

Abrégé

An anti-infective dressing bag and a fabricating method therefor. The anti-infective dressing bag is frabicated integrally by using an electrospinning technology, or fabricated with multicomponent nanofibers integrally by using a coaxial electrospinning technology. The multicomponent nanofiber comprise a core layer (1) and a surface layer (2), and the surface layer (2) is coated on the outside of the core layer (1). The core layer (1) is made of a biodegradable material or a non-biodegradable material, and the surface layer (2) is a mixed layer formed by a biodegradable material and medicine. The medicine is uniformly distributed in the biodegradable material of the surface layer (2).

Classes IPC  ?

• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 31/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61L 31/04 - Matériaux macromoléculaires
• D04H 1/728 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes caractérisés par la méthode de formation des voiles ou couches, p. ex. par la réorientation des fibres les fibres étant disposées au hasard par électrofilage
• D01D 5/00 - Formation des filaments, fils ou similaires
• D01D 5/34 - Structure "âme-gaine"Ensembles de filage à cet effet

Produits et services

stents for medical purposes; catheters for medical purposes; [ medical guidewires; trocars; electrodes for medical use; gloves for medical purposes; ] surgical implants comprised of artificial materials [ ; suture materials ]

Produits et services

balloon dilatation catheter.

Produits et services

Medical apparatus and instruments; stents for medical purpose; catheters for medical purpose; medical guidewires; trocars; electrodes for medical use; gloves for medical purposes; surgical implants [artificial materials]; orthopaedic articles; suture materials.

Abrégé

An anticoagulation coating is formed on the surface of a carrier, and the coating is formed by alternate adsorption of positively charged and negatively charged polyelectrolytes. The present invention has a simple process, can be achieved through a simple solution circulating device, and can obtain a stable coating structure through cross-linking. The preparation method of the present invention is implemented in a mild aqueous environment, has no toxicity of solvents, and is environmental-friendly. After ultrasonic treatment of the polyelectrolyte solution, the solute dispersion of the polyelectrolyte is good, the agglomeration is avoided, and the coating is more even.

Classes IPC  ?

• A61L 33/08 - Polysaccharides
• C08J 7/04 - Revêtement

Abrégé

A degradable polyester stent is disclosed, which includes a polyester composite, wherein the polyester composite is produced from a biodegradable polyester and a metal-based material. A method of preparing the degradable polyester stent is also disclosed. The method can improve the mechanical properties of the biodegradable copolymer stent and can achieve the radiopacity of the main body and the overall of the stent.

Classes IPC  ?

• A61F 2/06 - Vaisseaux sanguins
• A61F 2/90 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles
• A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents
• C08L 67/04 - Polyesters dérivés des acides hydroxycarboxyliques, p. ex. lactones
• A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 31/12 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent

Produits et services

Medical apparatus and instruments; stents; cannulae; medical guidewires; trocars; electrodes for medical use; gloves for medical purposes; surgical implants [artificial materials]; orthopedic articles/orthopaedic articles; suture materials.