Abrégé

A vapor exposure model experimental device, comprising: an exposure chamber (1), which is divided into a plurality of vapor compartments (101); an air intake mechanism (2), which is fixed in the exposure chamber, and which is provided with a plurality of air inlets (203) and a plurality of air outlets (204), each air inlet (203) being in communication with one corresponding vapor compartment (101), and each air outlet (204) being in communication with one corresponding vapor compartment (101); a vapor generator (3), which is in communication with the air inlets (203) of the air intake mechanism (2); and a camera (4), which is arranged above the exposure chamber (1) and used for observing the exposure chamber (1). The vapor exposure model experimental device enables vapor exposure experiments to be conducted by means of the exposure chamber (1) and the vapor generator (3), and the air intake mechanism (2) provides the same exposure condition for the vapor compartments (101), facilitating synchronous vapor experiments on different experimental subjects; thus, the device involves an easy operation while enabling online real-time observation of experimental subject behavior.

Classes IPC  ?

• A61D 7/04 - Dispositifs pour anesthésier les animaux au moyen de gaz ou vapeursDispositifs pour inhalations
• A61D 7/00 - Dispositifs ou méthodes pour l'introduction de remèdes, solides, liquides ou gazeux ou d'autres produits dans ou sur le corps des animaux

Abrégé

The present application relates to the field of behavior analysis. Provided are a behavior analysis method and apparatus, and an electronic device and a storage medium. The method comprises: acquiring an image sequence, wherein the image sequence comprises at least one image frame, and each image is generated during a process in which a vapor exposure apparatus delivers the same or different vapor to at least one test target; performing pose estimation on each test target in each image to obtain key point information of each test target under different exposure times; and on the basis of the key point information of each test target under different exposure times, performing quantitative analysis on the behavior of each test target under at least one vapor exposure condition to obtain a behavior difference result of each test target. The present application solves the problems in the related art of low efficiency and insufficient accuracy of behavior analysis.

Classes IPC  ?

• G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes

Abrégé

The present application relates to the technical field of biological devices. Disclosed is a device for measuring nerve fiber action potentials. The device can not only synchronously measure the action potentials of all nerve fibers in a peripheral nerve, but can also slow down the inactivation rate of the peripheral nerve, thereby improving the stability of the measurement results. The device comprises a box, wherein a working chamber and a thermal insulation chamber below the working chamber are defined in the box; a vertical partition is provided in the working chamber; the vertical partition divides the working chamber into a stimulation chamber and a recording chamber; a stimulation electrode group is provided in the stimulation chamber; an oxygen-containing-liquid inlet and an oxygen-containing-liquid outlet are provided in side walls of the stimulation chamber; the oxygen-containing-liquid inlet is in communication with an oxygen-containing-liquid source via a peristaltic pump; a plurality of recording electrode groups are provided in the recording chamber, and are distributed in multiple layers; and the vertical partition plate can hold a peripheral nerve to be tested. The present application is intended to improve the performance of a nerve action potential measurement device.

Classes IPC  ?

• A61B 5/388 - Études de la conduction nerveuse, p. ex. détection du potentiel d’action d’un nerf périphérique
• G01R 29/12 - Mesure du champ électrostatique

Abrégé

A manufacturing method for a carbon-nanotube cold cathode (5), comprising the following steps: providing a positioning plate (1), the positioning plate (1) being provided with at least one positioning hole (11); providing a cold cathode substrate (2); embedding the cold cathode substrate (2) in the positioning hole (11); and fitting a screen printing mesh plate (3) onto the positioning plate (1), and using a screen printing method to print a carbon-nanotube slurry on the surface of the cold cathode substrate (2), so as to prepare a carbon-nanotube cold cathode (5). An X-ray tube electron gun assembly comprises the carbon-nanotube cold cathode (5). The manufacturing method for the carbon-nanotube cold cathode (5) uses the positioning plate (1) having a larger area for positioning, achieving accurate and reliable positioning and simple operation, and having low requirement for the appearance of the cold cathode substrate (2), thus achieving high applicability; using the positioning plate (1) for positioning not only increases the accuracy of an array pattern of the carbon-nanotube cold cathode (5), but also improves the array pattern quality and increases the reuse rate of the screen printing mesh plate (3).

Classes IPC  ?

• H01J 9/02 - Fabrication des électrodes ou des systèmes d'électrodes
• H01J 35/06 - Cathodes
• H01J 35/00 - Tubes à rayons X

Abrégé

A modular ultrasonic generation device and an ultrasonic manipulation method for microparticles. The modular ultrasonic generation device is configured to generate an acoustic field for manipulating the movement of a target object (300). The device comprises an ultrasonic transducer (100) and a modulation member (200); the ultrasonic transducer (100) is configured to generate a planar wave; the modulation member (200) is provided on a propagation path of the planar wave and located between the ultrasonic transducer (100) and the target object (300), and the modulation member (200) can modulate the planar wave into a target acoustic field for manipulating the target object (300) so as to drive the target object (300) to move along a set movement path; and the modulation member (200) comprises a plurality of unit modules (210) capable of modulating corresponding sub-acoustic fields, and the unit modules (210) are spliced to superimpose the sub-acoustic fields to form the target acoustic field. In the modular ultrasonic generation device, diversified acoustic fields for manipulation having different functions are realized by means of the splicing of the plurality of unit modules (210), and dynamic combination can be performed according to manipulation requirements in different application scenarios to form different modulation members (200), so as to modulate microparticle manipulation modes having different functions.

Classes IPC  ?

• B06B 3/00 - Procédés ou appareils spécialement adaptés pour transmettre des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore
• G10K 11/36 - Dispositifs pour transformer les ondes acoustiques de surface

Abrégé

Disclosed is an expression method for CSTN3 protein, comprising: providing a humanized CSTN3 extracellular segment full-length gene as a target gene; linking the target gene to a mammalian cell secretory expression vector, so as to construct a recombinant expression vector containing the target gene; instantaneously transfecting a mammalian cell with the recombinant expression vector by means of mediation with a transfection reagent; and culturing the transfected mammalian cell. The method is characterized in that the recombinant CSTN3 protein can be obtained simply by collecting a cell supernatant and then performing affinity separation by means of a nickel column without the need of cell disruption. Also disclosed are a recombinant expression vector containing the humanized CSTN3 extracellular segment full-length gene and a recombinant HEK293F cell containing the mammalian cell secretory expression vector containing the humanized CSTN3 extracellular segment full-length gene. The present application achieves rapid, stable and efficient expression of the target protein CSTN3 and achieves a high level of protein folding expression and stable quality. In addition, the culture process only needs using a small amount of a serum-free culture medium, thereby achieving a low cost.

Classes IPC  ?

• C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
• C12N 15/12 - Gènes codant pour des protéines animales
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères

Abrégé

A method for producing glucose and derivatives thereof by means of biotransformation with a recombinant yeast, which belongs to the technical field of synthetic biology. A construction method comprises any one of the following steps: i, knocking out metabolic pathway-related enzymes of glucose and derivatives thereof in a yeast strain; ii, enhancing or using an activity of synthetic pathway-related enzymes of glucose and derivatives thereof in the yeast strain; and iii, enhancing or using a capability of glucose and derivatives thereof in the yeast strain to enter and exit the yeast. Further provided are a recombinant yeast strain capable of producing glucose or derivatives thereof at a high yield and the use thereof in the conversion of a non-grain low-carbon carbon source. The low-carbon non-grain carbon source synthesized by means of using photoelectrocatalysis or traditional chemical industry is used as a substrate, and rapid preparation of food product raw materials glucose and derivatives thereof from the non-grain carbon source is realized by means of recombinant yeast cells.

Classes IPC  ?

• C12P 19/02 - Monosaccharides
• C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
• C12N 1/18 - Levure de boulangerieLevure de bière
• C12N 9/10 - Transférases (2.)
• C12N 9/12 - Transférases (2.) transférant des groupes contenant du phosphore, p. ex. kinases (2.7)
• C12N 9/16 - Hydrolases (3.) agissant sur les liaisons esters (3.1)
• C12N 9/24 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2)
• C12P 19/12 - Disaccharides
• C12P 19/26 - Préparation d'hydrates de carbone contenant de l'azote
• C12R 1/84 - Pichia
• C12R 1/865 - Saccharomyces cerevisiae

Abrégé

The use of a micro-lens chip (10) in particle tracking. A particle tracking apparatus (1) comprising a micro-lens chip (10). A particle tracking method for performing particle tracking by means of a micro-lens chip (10). The use of a micro-lens chip (10) in particle tracking performed by a particle tracking apparatus (1) by means of a particle tracking method.

Classes IPC  ?

• G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
• G02B 3/00 - Lentilles simples ou composées

Abrégé

The embodiments of the present application belong to the technical field of ultrasonic control. Provided are a movement control system, a movement control method, a movement control apparatus, and a device and a storage medium. The movement control method comprises: a signal acquisition device, a signal processing device and an ultrasonic control device. The signal acquisition device acquires a target electroencephalogram signal, and the signal processing device performs electroencephalogram feature processing on the target electroencephalogram signal. The electroencephalogram feature processing specifically comprises: using a pre-trained movement direction recognition model to perform movement direction classification on target electroencephalogram feature data in the target electroencephalogram signal, so as to obtain movement direction data, also using the target electroencephalogram feature data to obtain a movement step length, and generating a movement control signal on the basis of the movement direction data and the movement step length. On the basis of the movement control signal, the ultrasonic control device controls a target object to move in a target direction. Therefore, non-contact ultrasonic control based on electroencephalogram control is realized, thereby improving the universality of ultrasonic control.

Classes IPC  ?

• B25J 9/16 - Commandes à programme

Abrégé

The present invention relates to an anisotropic soft tissue cutting simulation method and apparatus. The method comprises: constructing a cutting simulation environment of a target soft tissue by combining particles and a background Eulerian grid; the background Eulerian grid acquiring physical quantity information on the basis of performing simulated shearing on the target soft tissue; calculating the elastic energy of the particles on grid nodes of the background Eulerian grid on the basis of physical quantities; and when the elastic energy exceeds the elastic energy limit that the target soft tissue can withstand and the target soft tissue undergoes shear fracture, the particles updating their own positions on the basis of the physical quantities. According to the present application, to realize deformation simulation of an anisotropic soft tissue, anisotropic elastic energy terms are introduced into an MPM to realize shear fracture simulation of the anisotropic target soft tissue, making the shear simulation of the target soft tissue more realistic.

Classes IPC  ?

• G06F 30/25 - Optimisation, vérification ou simulation de l’objet conçu utilisant des méthodes basées sur les particules

Abrégé

Provided are an expression cassette, an expression vector, a recombinant microorganism, a heterologous expression method of a non-ribosomal peptide synthetic gene cluster, and the use thereof. The expression cassette comprises a promoter, the non-ribosomal peptide synthetic gene cluster and a terminator which are linked tandemly in sequence, the non-ribosomal peptide synthetic gene cluster containing N synthetic genes linked tandemly in sequence, and N being a positive integer greater than or equal to 2. At least one ribosome binding site is provided between each two adjacent synthetic genes. The promoter, the terminator and the ribosome binding site are derived from Bacillus subtilis, thus reducing the difficulty in expressing the non-ribosomal peptide synthetic gene cluster in a heterologous expression host (Bacillus subtilis).

Classes IPC  ?

• C12N 15/52 - Gènes codant pour des enzymes ou des proenzymes
• C12N 9/00 - Enzymes, p. ex. ligases (6.)ProenzymesCompositions les contenantProcédés pour préparer, activer, inhiber, séparer ou purifier des enzymes
• C12N 15/81 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons pour levures
• C12N 15/75 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora pour Bacillus
• C12N 1/21 - BactériesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• C12N 1/19 - LevuresLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• C12R 1/125 - Bacillus subtilis
• C12R 1/865 - Saccharomyces cerevisiae

Abrégé

Disclosed in the present invention are an adaptive temperature control system and method for a thermoelectric cooler based on transient supercooling. The system comprises: a temperature detection unit used for acquiring temperature information of a cold end of a thermoelectric cooler; a thermal load monitoring unit used for monitoring thermal load information of the thermoelectric cooler; a PID controller used for controlling and outputting a first current on the basis of the temperature information of the cold end and with an optimization goal of controlling the temperature of the cold end of the thermoelectric cooler to be a target temperature; a transient pulse controller used for controlling a current limit on the basis of the thermal load information; a feedforward controller used for adjusting an advanced control current on the basis of the thermal load information and outputting a second current; a limit output unit used for increasing a total current output limit of the first current and the second current to the current limit on the basis of the current limit generated by the transient pulse controller; and a power output unit used for driving the thermoelectric cooler on the basis of a current generated by the limit output unit. The present invention can significantly improve the thermal load resistance of the thermoelectric cooler and improve the precision and stability of temperature control.

Classes IPC  ?

• G05D 23/20 - Commande de la température caractérisée par l'utilisation de moyens électriques avec un élément sensible présentant une variation de ses propriétés électriques ou magnétiques avec les changements de température

Abrégé

The present application relates to the technical field of collection for medical waste, and relates to an embedded automatic disinfection negative pressure collecting apparatus and method for medical waste. The apparatus comprises a mounting part, a negative pressure maintaining module, and a lid opening module. The mounting part is nested and arranged on a barrel opening of a garbage can, the mounting part is provided with a throwing through hole, the throwing through hole is arranged corresponding to the barrel opening of the garbage can, and an accommodating space is formed inside the mounting part. The negative pressure maintaining module is disposed in the accommodating space, and the negative pressure maintaining module extends into the throwing through hole. The lid opening module is rotatably arranged on the mounting part. The mounting part is provided with a central control apparatus, and both the lid opening module and the negative pressure maintaining module are electrically connected to the central control apparatus. The mounting part can be embedded into a position above the garbage can and a negative pressure environment is formed in the garbage can, so that when the lid opening module is opened and medical waste is dumped into the garbage can, the smell in the garbage can is not inhaled by medical staff. Therefore, the problem that an existing garbage can on the market cannot be adapted to a negative pressure apparatus is solved.

Classes IPC  ?

• B65F 1/10 - Récipients à ordures avec moyens de remplissage, p. ex. sacs pneumatiques
• B65F 1/16 - Capots ou couvercles
• B65F 1/14 - Autres caractéristiques de structure

Abrégé

A method for separating an exosome from a heterologous expression cell or a primary culture cell, and a use of an exosome in biological analysis, relating to the technical field of biomedicine. The method for separating the exosome from the heterologous expression cell or the primary culture cell of the present invention comprises: carrying out differential centrifugation on a solution to be extracted that contains an exosome, then taking out a first supernatant, carrying out high-speed centrifugation again, respectively adding iodixanol into an obtained second supernatant and a precipitate, and carrying out spontaneous density gradient centrifugation to obtain a separated purified exosome. According to the present invention, an iodixanol spontaneous density gradient centrifugation method is innovatively used to successfully carry out separation and purification to obtain the exosome having high purity and high yield, and the separated exosome is used as an experimental development universal platform for researching a membrane protein structure and functional characteristics in an original ecological cell membrane environment, and is used for biological analysis, drug screening, and disease diagnosis and treatment.

Classes IPC  ?

• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée

Abrégé

A preparation method for a perovskite solar cell module and a large-area uniform perovskite thin film. The structure of the perovskite thin film solar cell module can be divided into a substrate, a hole transport layer, an interface modification layer, a perovskite absorption layer, an electron transport layer, a hole blocking layer, and a back electrode from bottom to top. The perovskite absorption layer is prepared by increasing DMF pre-wetting. The problems of a thin film uniformity requirement and a hole defect in the preparation process of a p-i-n trans-structure large-area perovskite thin film solution method are solved.

Classes IPC  ?

• H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
• H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
• H10K 85/50 - Pérovskites organiquesPérovskites hybrides organiques-inorganiques [HOIP], p. ex. CH3NH3PbI3

Abrégé

Provided is a negative electrode active material for a sodium ion battery. The negative electrode active material comprises reticulated hard carbon, hard carbon particles, and active metal particles; and the hard carbon particles and the active metal particles are distributed in the reticulated hard carbon and are fixed by the reticulated hard carbon. The production cost of the negative electrode active material for a sodium ion battery is reduced, and the capacity, the cycle performance and the rate performance of the negative electrode active material are improved. Further provided are a preparation method for and a use of the negative electrode active material for a sodium ion battery.

Classes IPC  ?

• H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
• H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
• H01M 10/054 - Accumulateurs à insertion ou intercalation de métaux autres que le lithium, p. ex. au magnésium ou à l'aluminium

Abrégé

33. The method comprises: subjecting the metal halide perovskite single crystal to wire cutting, grinding and polishing, and polishing the metal halide perovskite single crystal by utilizing a polishing paste and diamond oil. Moreover, without any damage to the surface of the perovskite single crystal and the charge collection efficiency of the perovskite single crystal, the requirement for the surface roughness of the perovskite single crystal during machining is met, and therefore the performance of a corresponding photovoltaic device is improved without any increase in the preparation difficulty of surface polishing of the perovskite single crystal.

Classes IPC  ?

• B28D 5/04 - Travail mécanique des pierres fines, pierres précieuses, cristaux, p. ex. des matériaux pour semi-conducteursAppareillages ou dispositifs à cet effet par outils autres que ceux du type rotatif, p. ex. par des outils animés d'un mouvement alternatif

Abrégé

An NK cell drug delivery system, a preparation method therefor and a use thereof, relating to the field of drugs. The NK cell drug delivery system comprises activated NK cells and drug-loaded nanoparticles linked to the surfaces of the activated NK cells; the activated NK cells are NK cells containing sulfhydryl on the surfaces; maleimide groups or sulfhydryl groups are contained on the surfaces of the drug-loaded nanoparticles; the drug-loaded nanoparticles are linked to sulfhydryl on the surfaces of the activated NK cells by means of the maleimide groups or the sulfhydryl groups; by means of the NK cells linked to sulfhydryl by means of the maleimide groups or the sulfhydryl groups, and the drug-loaded nanoparticles, the NK cell drug delivery system has high targeting performance and low biotoxicity on cells or tissues of brain diseases, and significantly improves the effect of treating brain diseases.

Classes IPC  ?

• A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
• A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
• A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
• A61K 35/17 - LymphocytesLymphocytes BLymphocytes TCellules tueuses naturellesLymphocytes activés par un interféron ou une cytokine
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux

Abrégé

A porous diamond coating, and a preparation method therefor and the use thereof. The porous diamond coating comprises a metal matrix, wherein a silicon carbide composite intermediate layer (3) is provided on the surface of the metal matrix, diamond grains (4) dispersed apart from each other are embedded in the silicon carbide composite intermediate layer (3), and gaps and a porous structure are formed among the dispersed diamond grains (4), thereby achieving an effect of preventing blockages caused by abrasive dust. When being used for a cutter, the porous diamond coating is good in terms of machining quality, high in terms of machining precision, low in terms of wear rate and long in terms of service life. In addition, the porous diamond coating is not limited by the shape of a tool, can achieve rapid controllable deposition on a miniature precision tool in any complex shape, and has the advantages of a wide application range, high precision, low cost, etc. Further provided are a preparation method for and the use of the porous diamond coating.

Classes IPC  ?

• C23C 16/02 - Pré-traitement du matériau à revêtir

Abrégé

Disclosed in the present invention is a secrecy rate optimization method for a simultaneous wireless information and power transfer system. The method comprises: constructing a simultaneous wireless information and power transfer system, which includes an intelligent reflecting surface apparatus, an access point, a plurality of legitimate users and a plurality of eavesdroppers, wherein the intelligent reflecting surface apparatus is provided with a plurality of reflecting elements, and adding artificial noise to an information signal transmitted by the access point; for the simultaneous wireless information and power transfer system, establishing a secrecy rate optimization problem, and in the secrecy rate optimization problem, taking interference between the users into consideration and describing channel state information of the eavesdroppers; and for the secrecy rate optimization problem, jointly optimizing a power splitting ratio, transmission beamforming, a covariance matrix for the artificial noise, and a phase shift matrix for the intelligent reflecting surface apparatus, wherein the power splitting ratio is used for limiting a legitimate user to splitting a power into an information decoding part and an energy harvesting part. The present invention is more applicable to an actual communication scenario, reduces the eavesdropping rate, and thus increases the overall rate of a system.

Classes IPC  ?

• H04W 12/02 - Protection de la confidentialité ou de l'anonymat, p. ex. protection des informations personnellement identifiables [PII]

Abrégé

00 into a spatial discretization representation; acquiring a correspondence between coarse and fine networks in the multi-level coarse and fine mesh representation (I); and performing correction calculation on the correspondence between the coarse and fine networks to obtain a node motion information iteration process of the coarse and fine meshes. The method significantly reduces network input while maximizing the retention of mesh space information, and reduces calculation resource consumption.

Classes IPC  ?

• G06F 30/10 - CAO géométrique
• G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle
• G06N 3/08 - Méthodes d'apprentissage

Abrégé

An experimental data processing method and apparatus, and a system, relating to the field of automatic data processing. The method comprises: sending a task preparation sequence instruction to a data computation system, so that the data computation system, on the basis of the task preparation sequence instruction, creates a task-related computation process, creates a data object in the computation process, and assigns an initial value (501); sending a data acquisition instruction to a device control end, and receiving data acquired by the device control end operating an experiment device; on the basis of the acquired data, generating a data modification instruction to the data computation system, so that the data computation system assigns a value to the data object in the related task computation process (502); sending a data computation instruction to the data computation system, so that, on the basis of the data computation instruction, the data computation system performs computation on data of the related task computation process (503); and sending a data output instruction to the data computation system, so as to, on the basis of the data output instruction, store in a data object database the data of the related computation process (504). According to the described method, a full-service process can be implemented. In addition, the method has the advantages of being easy to use and easy to learn and being versatile.

Classes IPC  ?

• G06F 16/25 - Systèmes d’intégration ou d’interfaçage impliquant les systèmes de gestion de bases de données
• G06F 16/2458 - Types spéciaux de requêtes, p. ex. requêtes statistiques, requêtes floues ou requêtes distribuées
• G06F 9/451 - Dispositions d’exécution pour interfaces utilisateur

Abrégé

The present application relates to the technical field of image processing. Provided are a stent identification method and apparatus, and a stent reconstruction method and apparatus. The stent identification method comprises: acquiring an original intravascular ultrasound (IVUS) image; performing anisotropic diffusion filtering on the original IVUS image to obtain an IVUS image in which stent signals are enhanced; processing the IVUS image in which the stent signals are enhanced, so as to form a binarized mask image that only includes the stent signals; and obtaining a stent identification result for the original IVUS image on the basis of the binarized mask image and the original IVUS image. Since IVUS has a greater imaging depth, even when the depth of a stent in a blood vessel is increased, stent signals can still be detected by means of IVUS, so that a situation where stents cannot be identified does not occur.

Classes IPC  ?

• G06V 20/60 - Type d’objets
• G06T 7/00 - Analyse d'image
• G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie
• G06V 10/28 - Quantification de l’image, p. ex. seuillage par histogramme visant à discriminer entre les formes d’arrière-plan et d’avant-plan
• G06V 10/30 - Filtrage de bruit

Abrégé

An animal behavior pattern mining system, a method, a computer device, and a storage medium. The system comprises a PC device (10) and an experiment box body (20); an infrared touch screen (25), a transparent box body (26), a camera (27), a thermal infrared probe (28) and a brain endoscope (29) are further separately provided in the experiment box body (20); the transparent box body (26) is used for placing an experimental animal; the infrared touch screen (25), the camera (27) and the thermal infrared probe (28) are respectively used for acquiring trajectory data, video images, and body temperature data of the experimental animal; the brain endoscope (29) is used for acquiring neuron signals of the experimental animal; and the PC device (10) is used for acquiring the behavior pattern category of the experimental animal on the basis of the trajectory data, the video images, the body temperature data and the neuron signals.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/369 - Électroencéphalographie [EEG]
• A61B 5/01 - Mesure de la température de parties du corps

Abrégé

A miniature drill bit, and a preparation method therefor and the use thereof. The miniature drill bit comprises a drill bit substrate and a superhard wear-resistant diamond coating arranged on a surface of the drill bit substrate, wherein the diameter of the drill bit substrate is 0.08-4 mm. The diameter of the drill bit substrate makes it an extremely-small-diameter drill bit, and a uniform diamond coating is further arranged on the extremely-small-diameter drill bit; therefore, the drill bit has good drilling machining performance and meets the development and machining trend of a packaging substrate. The invention solves the problems of most of the traditional diamond-coated miniature drill bits having a diameter of 1 mm or more, and having difficulties in terms of adapting to packaging substrates having a smaller size and finer holes.

Classes IPC  ?

• B26F 1/16 - Perforation par un ou plusieurs outils du type foret
• C23C 16/27 - Le diamant uniquement
• C23C 16/02 - Pré-traitement du matériau à revêtir
• C23G 1/14 - Nettoyage ou décapage de matériaux métalliques au moyen de solutions ou de sels fondus avec des solutions alcalines

Abrégé

A window structure capable of being overlapped and turned over, comprising: a frame; a first window body, which is connected to the frame in a turnover manner; a second window body, which is slidably connected to the first window body, wherein by means of sliding the second window body along the first window body, the second window body and the first window body are overlapped or extended; and a turnover driver, which is connected to the frame and the first window body and used for driving the overlapped first window body and second window body to turn over relative to the frame. The window structure capable of being overlapped and turned over in the present application can be opened by means of both sliding and turning over, such that the window structure can cover a large spatial range when same is opened.

Classes IPC  ?

• E06B 3/50 - Aménagements des battants caractérisés par le genre de mouvementAménagements des battants modèles dans les ouverturesCaractéristiques des battants ou châssis ayant trait uniquement au genre de mouvement du battant pour plusieurs genres de mouvement
• E06B 3/52 - Battants nécessitant une manœuvre de levée avant l'ouverture
• E05C 17/60 - Dispositifs pour le maintien des battants coulissants en position d'ouverture
• E05C 19/16 - Dispositifs maintenant le battant par attraction magnétique ou électro-magnétique
• E05F 1/10 - Appareils de fermeture ou d'ouverture pour battants, non prévus ailleurs dans la présente sous-classe actionnés par ressort pour battants pivotants

Abrégé

A preparation method for a sodium iron sulfate polyanion positive electrode material, and a device, relating to the technical field of secondary battery material manufacturing. The provided preparation method comprises: performing wet ball milling on sodium sulfate and ferrous sulfate and sintering the resulting mixture. The sintering is performed in a protective atmosphere having a flow rate of 0.024 to 20 mm/s; a moisture absorbent is present in the sintering environment, and the moisture absorbent is located downstream of the protective atmosphere; and the sintering comprises: sequentially performing constant-temperature treatment at 60-120°C, 150-250°C, and 300-380°C. By means of the provided preparation method, the number of instruments used can be effectively reduced, the number of steps of the preparation method is reduced, and finally, the preparation costs are reduced. Also provided is a device for implementing the preparation method.

Classes IPC  ?

• H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates

Abrégé

Provided is an in-vitro electrophysiological experiment method. The method comprises: injecting into a target tissue or organ an rAAV expressing a low-abundance fluorescent protein, the genome of the rAAV expressing a low-abundance fluorescent protein containing any one among the following a)-c): a) a promoter sequence, a fluorescent protein gene sequence and a PEST sequence; b) a promoter sequence, a fluorescent protein gene sequence and an ecDHFR DD sequence; and c) a TRE promoter sequence and a fluorescent protein gene sequence, the TRE promoter sequence being located at the upstream of the fluorescent protein gene sequence; and when the fluorescent protein has been expressed for a period of time, performing an in-vitro electrophysiological experiment on the target tissue or organ. The rAAV expresses a low-abundance fluorescent protein, the accumulation of fluorescent proteins in cells is reduced, the cytotoxicity is reduced, and the influence on experimental results is relatively small. In addition, low-abundance fluorescent proteins make cells easier to observe and distinguish from other fluorescent cells in the surrounding area in experiments.

Classes IPC  ?

• G01N 33/483 - Analyse physique de matériau biologique
• G01N 21/64 - FluorescencePhosphorescence
• C12N 15/864 - Vecteurs parvoviraux
• C12N 15/65 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression utilisant des marqueurs

Abrégé

A composite carbon material, and a preparation method therefor and a use thereof. The composite carbon material comprises activated carbon and a soft carbon layer covering the surface of the activated carbon; the activated carbon is selected from at least one of coal-based activated carbon, coconut shell activated carbon, and bamboo charcoal activated carbon; the soft carbon layer comprises sodium storage active pores, and the soft carbon layer is prepared by melting a soft carbon precursor, and then coating the surface of activated carbon with the soft carbon precursor and carrying out primary calcination. The material is easy to prepare and environmentally friendly, has low raw material costs, a small specific surface area, abundant sodium storage active pores and a stable structure, and can fully exert the matrix and mass transfer effects of activated carbon; because of the fluidity of the soft carbon precursor and the activity of soft carbon, pores in the surface of activated carbon are effectively converted into the sodium storage active pores; and a sodium-ion battery prepared by using the composite carbon material as a negative electrode active material can have the advantages of high specific capacity, high initial coulombic efficiency, good cycle reversibility, good long-cycle stability, good rate performance, etc.

Classes IPC  ?

• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 4/587 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
• H01M 4/04 - Procédés de fabrication en général
• H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
• H01M 4/133 - Électrodes à base de matériau carboné, p. ex. composés d'intercalation du graphite ou CFx

Abrégé

2222.

Classes IPC  ?

• C25B 11/032 - Électrodes à diffusion de gaz
• C25B 3/07 - Composés contenant au moins un atome d’oxygène
• C25B 3/26 - Réduction du dioxyde de carbone
• C25B 11/048 - Composés organiques

Abrégé

The present application provides a preparation method for a gas diffusion electrode for electrocatalytic CO2 reduction to CO, comprising: mixing a conductive polymer monomer solution and a metal salt solution at a molar ratio of 100:1 to 1:100 and adding a dispersant to form a mixed solution; and transferring the mixed solution onto a substrate, and reacting at a temperature ranging from -30°C to 50°C for 1-48 h to obtain a gas diffusion electrode. According to the present application, a metal-conductive polymer gas diffusion electrode is formed by means of in-situ growth of conductive polymer monomers self-initiated by metal ions; due to the characteristics of the conductive polymer, the gas diffusion electrode can provide more nucleation sites, reducing the usage amount of metal while achieving similar catalytic effects; secondly, the special structure of the conductive polymer improves the electron transfer rate and the CO2 adsorption capacity on the electrode surface, helping to improve the product selectivity; and finally, the conductive polymer is an organic macromolecular long-chain structure, and the substrate, metal particles and metal-ligand complex to which the conductive polymer is bound can be stabilized by means of cross-linking, thereby improving the stability of the electrode.

Classes IPC  ?

• C25B 11/032 - Électrodes à diffusion de gaz
• C25B 3/07 - Composés contenant au moins un atome d’oxygène

Abrégé

Provided in the present invention is a preparation method for an Fe-Co-Ni-Cu-Zn high-entropy sensing material. The Fe-Co-Ni-Cu-Zn high-entropy sensing material is obtained by preparing an electroplating solution, adjusting the concentration and pH value of an electrolyte, and preparing a sensitive material from Fe, Co, Ni, Cu and Zn by means of an electrochemical method. The preparation method is simple and convenient to operate, and relatively low in terms of cost and energy consumption; and the elemental composition, structural morphology, performance, etc., of the high-entropy alloy can be easily controlled by changing the deposition parameters (time, temperature, etc.) of electrochemical deposition. The Fe-Co-Ni-Cu-Zn high-entropy sensing material prepared in the present application can be used as a sensing electrode to test urea and glucose solutions having different concentrations, and has high detection precision, good stability and high sensitivity.

Classes IPC  ?

• C25D 3/56 - Dépôt électrochimiqueBains utilisés à partir de solutions d'alliages
• C25D 5/34 - Prétraitement des surfaces métalliques à revêtir de métaux par voie électrolytique
• C25D 7/00 - Dépôt électrochimique caractérisé par l'objet à revêtir
• G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide

Abrégé

A kit for detecting trace nitrite, a detection system and a related method. The kit comprises a nitrite detection reagent, the nitrite detection reagent comprising the following component raw materials in parts by mass: 0.5-50.0 parts of sulfanilic acid, 0.1-20.0 parts of hydrochloride naphthodiamide, 10.0-90.0% of a weighting agent, 1.0-60.0 parts of a masking agent and 0-10.0 parts of an accelerator. Compared with conventional methods or other measurement forms, the kit, the detection system and the related method offer more convenient use, easy formulation, safe and simple operation and low cost, and do not require specialized technicians for measurement. Reagents used in the kit are all common chemical reagents, which are safe, reliable and low in price.

Classes IPC  ?

• G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur

Abrégé

The present invention provides a kit for detecting nitrate in water, a detection system, and related methods. A first aspect of the present invention provides a kit for detecting nitrate in water. The kit comprises a nitrate detection reagent. The nitrate detection reagent comprises the following component raw materials in parts by mass: 0.1-10.0 parts of a reducing agent, 0.5-50.0 parts of p-aminobenzene sulfonic acid, 0.1-20.0 parts of N-(1-naphthyl)ethylenediamine dihydrochloride, 1.0-60.0 parts of a masking agent, 10.0-90.0 parts of a weighting agent, and 0-10.0 parts of an accelerant. According to the present invention, the reagent in the kit discolors immediately upon contact with nitrate, without the need for any complex analysis device, thereby realizing low-cost, instant and trace detection of nitrate. The reagent allows for simple and convenient operation, high sensitivity, and low costs, thereby providing an effective technical means for the field of detection of nitrate ions in water. The detection reagent shows a low detection limit (visual detection limit of 0.1 mg/mL) and extremely high selectivity for nitrate, thereby guaranteeing that the present invention can be applied to detect nitrate in water.

Classes IPC  ?

• G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur

Abrégé

Disclosed in embodiments of the present invention are a pathological image analysis method and apparatus. The method comprises: acquiring a pathological image data set, pathological images having different magnifications; respectively cutting the pathological images to obtain a plurality of image blocks in the pathological images; performing feature extraction on the image blocks to obtain image features of the image blocks, and performing feature fusion on the image features of the image blocks on the basis of the correspondence between the image blocks to obtain multi-magnification features of the image blocks; constructing a panoramic image on the basis of the image blocks having different magnifications, a spatial positional relationship of the image blocks in the pathological images to which the image blocks belong, and the multi-magnification features of the image blocks; inputting the panoramic image into a constructed context information perception model to learn graph structure information and context information in the pathological images, so as to obtain an analysis result of the pathological image data set; and applying the analysis result to a target task. The present invention solves the problem in the prior art of low accuracy caused by failure in full acquisition of feature information.

Classes IPC  ?

• G06T 7/00 - Analyse d'image

Abrégé

Disclosed in the present invention is a control system for a micro-nano robot magnetic control platform. The system is arranged in a main control computer and is connected to a magnetic control platform terminal device. The system comprises a main control unit, a display unit, a magnetic field parameter setting unit, a camera parameter setting unit, a user-defined magnetic field setting unit, a keyboard operation unit, a micro-nano robot object detection unit, a magnetic field measurement unit, a printing output unit and a magnetic control platform state unit. By coordinating the functions and interactions of the units, the present invention helps to set magnetic field parameters, monitor the states of motion of micro-nano robots in real time, communicate with micro-nano robot magnetic control platform terminals and comprehensively calculate and store magnetic field sensor data, can control magnetic control platforms to generate any magnetic field type, and controls the magnetic control platforms by means of keyboard keys, so as to accurately and visually control the micro-nano robots.

Classes IPC  ?

• B25J 9/16 - Commandes à programme
• B25J 7/00 - Micromanipulateurs
• B25J 13/00 - Commandes pour manipulateurs

Abrégé

A hard carbon negative electrode material as well as a preparation method therefor and a use thereof. The hard carbon negative electrode material comprises a hard carbon base material, heteroatoms and metal monoatoms, wherein the metal monoatoms are doped into the hard carbon base material by means of the heteroatoms, the heteroatoms comprise at least one of N, P or S, and the metal monoatoms are metal monoatoms that can undergo an alloying reaction with sodium. The metal monoatoms are doped into the hard carbon base material by means of covalent (chemical bond) interactions with other heteroatoms, so that the doping of single atoms is achieved, thereby improving the overall capacity and rate capability of a sodium ion battery at normal temperature, and ensuring the capacity retention rate of the sodium ion battery under a low temperature condition.

Classes IPC  ?

• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 4/583 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx
• H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
• H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
• C01B 32/05 - Préparation ou purification du carbone non couvertes par les groupes , , ,

Abrégé

Disclosed in the present invention are a GPU feature mining and analysis method and system based on computer microarchitecture independence. The method comprises: building a target instrumentation library, analyzing a calling sequence of a target application program, and extracting a plurality of levels of performance features, wherein the performance features are high-level features of a program and are independent of a microarchitecture of a processor; analyzing a correlation between the performance features and execution performance of the target application program; and outputting an analysis result according to the obtained correlation, wherein the analysis result reflects a performance bottleneck of the target application program and a corresponding optimization suggestion. The present invention can help developers to adjust and optimize application programs, so as to fully use computing capabilities of GPUs.

Classes IPC  ?

• G06F 9/38 - Exécution simultanée d'instructions, p. ex. pipeline ou lecture en mémoire

Abrégé

Provided is a drug for treating rheumatoid arthritis, the drug comprising a gene therapy vector, and the gene therapy vector comprising a nucleic acid sequence encoding quinolinate phosphoribosyltransferase (QPRT). The provided drug provides prolonged or sustained QPRT in vivo, which can restore or enhance the capability of cells producing NAD+ and regulate processes in secretion pathways, thereby preventing pathological secretion of cytokines, stopping the inflammatory progression at the origin, and effectively avoiding immune response, neovascularization and tissue destruction in joints. The provided drug based on gene therapy can improve spatial and temporal distribution, improve the treatment effect and reduce side effects; the drug achieves prolonged or sustained QPRT release, and thus has long efficacy; and, along with the prolonged expression of QPRT, the dosage of the drug can be reduced.

Classes IPC  ?

• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• C12N 9/10 - Transférases (2.)
• A61K 38/45 - Transférases (2)
• A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
• A61P 37/02 - Immunomodulateurs
• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique

Abrégé

A variable-stiffness magnetic drive catheter, which relates to the technical field of medical instruments. It is not only possible to improve the steering flexibility of the catheter, but also to ensure that the overall maximum stiffness can meet the requirements of advancing, sampling and other operations and also improve the steering flexibility and controllability of the catheter. The variable-stiffness magnetic drive catheter comprises a main rigid tube (1), a hollow flexible tube (2), a limit tube (3) and a magnetic component, which are sequentially arranged in an axial direction, wherein a magnetic spiral tube (5) is sleeved on the main rigid tube (1); the main rigid tube (1) has an inner diameter and an outer diameter equal to those of the hollow flexible tube (2); the limit tube (3) has an inner diameter equal to that of the main rigid tube (1), and has an outer diameter greater than that of the magnetic spiral tube (5); the main rigid tube (1), the hollow flexible tube (2) and the limit tube (3) are all made of soft materials, and the main rigid tube (1), the limit tube (3) and the magnetic component each have a stiffness greater than that of the hollow flexible tube (2); and the magnetic spiral tube (5) can spirally move forward or backward on a surface of the main rigid tube (1) and a surface of the hollow flexible tube (2), thereby improving the performance of the catheter.

Classes IPC  ?

• A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
• A61M 25/00 - CathétersSondes creuses

Abrégé

A kit for detecting COD, and a preparation method therefor and the use thereof. The kit for detecting COD comprises a reagent tube loaded with a COD detection reagent, and a standard colorimetric card, wherein the COD detection reagent comprises potassium permanganate, a strong alkaline reagent and a weighting agent. The strong alkaline reagent comprises one of or a mixture of sodium carbonate, sodium bicarbonate and sodium phosphate; and the weighting agent comprises one of or a mixture of calcium carbonate, sodium sulfate and potassium sulfate. The kit is based on a potassium permanganate method, wherein reducing substances in water are oxidized under alkaline conditions, and manganese in different valence states is obtained in the case of different amounts of the reducing substances, thereby presenting different colors. The kit has the advantages of no need for instruments and devices, low cost, convenience, rapidness, flexibility, stability, etc., is simple in terms of actual operation, causes little pollution to a laboratory environment, and can be widely used.

Classes IPC  ?

• G01N 33/18 - Eau
• G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur

Abrégé

A use of a CD317 siRNA combined with an AMPK inhibitor or an AMPK siRNA in tumor treatment, relating to the technical field of biomedicines. Provided is a use of a CD317 siRNA or CD317 inhibitor combined with an AMPK inhibitor or an AMPK siRNA in the preparation of a drug for treating tumor diseases. The CD317 siRNA or CD317 inhibitor inhibits CD317 expression by means of gene silencing or gene editing, or performs targeted degradation on a CD317 protein by means of PROTAC and LYTAC technologies. The expression of cancer cell CD317 is reduced by means of the CD317 siRNA or CD317 inhibitor, thereby inhibiting an AMPK signal, enhancing the sensitivity of tumor cells to the AMPK inhibitor. A combination of the CD317 inhibitor and the AMPK inhibitor can significantly promote tumor cell death, providing a new anti-tumor method.

Classes IPC  ?

• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61P 35/00 - Agents anticancéreux

Abrégé

222 by water can be greatly improved, and the treated surface can achieve good hydroxylation, thereby greatly reducing the contact angle between same and water; the contact angle is relatively large after the anti-fingerprint film is coated, thereby effectively improving the hydrophobicity and friction resistance of the anti-fingerprint film; and the plasma treatment process is simple, energy-saving, environmentally friendly, pollution-free and highly efficient, and takes a short period of time, thus providing an important approach for achieving large-scale treatment and improvement of the friction resistance of the anti-fingerprint film.

Classes IPC  ?

• C03C 17/32 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des matières organiques avec des résines synthétiques ou naturelles
• C03C 23/00 - Autres traitements de surface du verre, autre que sous forme de fibres ou de filaments

Abrégé

The present invention relates to a modified bacterium having an anti-tumor activity. The bacterium contains a hypoxia-regulated lipopolysaccharide (LPS) gene expression cassette containing a gene involved in LPS biosynthesis or transport or a gene encoding a murein lipoprotein which is controlled by a first strictly hypoxia-inducible promoter. The bacterium further contains an essential gene expression cassette controlled by a strictly hypoxia-inducible promoter; and at least one gene or a functional expression product thereof that participates or regulates the endogenous response pathway against oxidative stress is deleted from the bacterium. The present invention further relates to a pharmaceutical composition containing the modified bacterium, and the anti-tumor use thereof.

Classes IPC  ?

• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora
• C12N 1/21 - BactériesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression
• C12N 1/36 - Adaptation ou atténuation de cellules
• A61P 35/00 - Agents anticancéreux

Abrégé

Provided are a fusion protein, comprising an antibody that binds to a neutrophil or an antigen-binding fragment thereof, and a cytotoxin or an active fragment thereof. Also provided are modified bacteria having anti-tumor activity and expressing the fusion protein, the antibody or the antigen-binding fragment thereof, or the toxin or the active fragment thereof in a low-oxygen environment (such as a tumor). Also provided are a pharmaceutical composition comprising the modified bacteria and an anti-tumor use thereof.

Classes IPC  ?

• C07K 16/46 - Immunoglobulines hybrides
• C07K 16/32 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des produits de traduction des oncogènes
• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 35/74 - Bactéries
• A61P 35/00 - Agents anticancéreux
• C07K 19/00 - Peptides hybrides
• C12N 1/21 - BactériesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger

Abrégé

A learning-based AR-assisted dental treatment automatic calibration and navigation method, comprising: using a virtual reality display device to acquire a 3D mandible model of a target; inputting the 3D mandible model into a trained feature point detection network to identify a plurality of corresponding feature points; aligning the plurality of feature points with feature points of a corresponding real 3D mandible model so as to calibrate and navigate onto the real model the virtual model under the virtual reality display device, wherein the feature points of the real 3D mandible model are detected by using a depth camera; and on the basis of a multi-feature iterative nearest point algorithm, combining a virtual environment and the real environment to complete the display of the virtual projection in the real environment. The method improves the efficiency and accuracy of automatic calibration and navigation of dental treatment.

Classes IPC  ?

• A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
• A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre

Abrégé

A transient response time determination method and apparatus, a device, and a storage medium. The transient response time determination method comprises: on the basis of transient response time of a signal conditioning module, transient response time of signal amplitude processing, transient response time of signal phase processing, first transmission time, and second transmission time, determining the slowest transient response time and the fastest transient response time of an amplitude link and the slowest transient response time and the fastest transient response time of a phase link; and on the basis of the slowest transient response time and the fastest transient response time of the amplitude link and the slowest transient response time and the fastest transient response time of the phase link, determining average transient response time of the amplitude link, average transient response time of the phase link, and delay time of a delay module.

Classes IPC  ?

• G01R 33/58 - Étalonnage des systèmes d'imagerie, p. ex. utilisant des sondes d'essai
• G01R 33/54 - Systèmes de traitement du signal, p. ex. utilisant des séquences d'impulsions
• G01R 33/36 - Détails électriques, p. ex. adaptations ou couplage de la bobine au récepteur
• A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique

Abrégé

A kit/test paper for detecting ammonia nitrogen, and a detection system and a related method thereof. A reagent in the kit/test paper comprise the following raw materials in parts by mass: 50-500 parts of a buffering agent, 0-500 parts of a masking agent, 0-500 parts of a stabilizer, 50-500 parts of a color developing agent, 2-100 parts of an oxidizing agent, and 1-100 parts of a catalyst. The specification of the reagent is 0.1 g per tube. The preparation process is simple, no special environmental requirement is required, no special three-waste pollution is caused, the cost is low, the detection steps are simple, the determination is more accurate, the color developing time is short, and the mobility is high. The reagents used are common chemical reagents, are safe and reliable, and have low price. The kit/test paper has a wide application range, and can be used for measuring the content of ammonia nitrogen in water bodies such as chemical wastewater, surface water, urban wastewater recycling-landscape environment water and urban miscellaneous water, especially for environmentally friendly monitoring of ammonia nitrogen.

Classes IPC  ?

• G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur

Abrégé

An effect of cordycepin in the field of fat protection, specifically an application of cordycepin in the preparation of fat protection products in the field of treatment of mental illness or sub-healthy mental state, the therapeutic dose is 25 mg cordycepin per kilogram of body weight. 25 mg/kg cordycepin can increase the weight reduction of white adipose tissue (sWAT) and perirenal white adipose tissue (pWAT) induced by stress, significantly reduce the abundance of Prevotellaceae UCG-001, increase the abundance of Desulfovibrio, and have an anti-anxiety or depression tendency.

Classes IPC  ?

• A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p. ex. adénosine, acide adénylique
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61P 25/22 - Anxiolytiques
• A61P 25/24 - Antidépresseurs
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• A61P 25/20 - HypnotiquesSédatifs

Abrégé

A sodium iron sulfate, and a preparation method therefor and a use thereof, relating to the technical field of secondary battery materials. The preparation method comprises: carrying out microwave solvothermal reaction on a mixed solution of a sodium source, an iron source, a sulfur source and an antioxidant, wherein during the microwave solvothermal reaction, the temperature is sequentially maintained at temperatures T1, T1', T2, T2' and T3, the temperatures T1, T2 and T3 are separately independently selected from 200-350°C, and the temperatures T1' and T2' are separately independently selected from 100-180°C. According to the preparation method, sodium iron sulfate having particle size gradation can be prepared, and the tap density of the sodium iron sulfate is improved, thereby improving the high-rate capacity and the high-rate cycle performance when the sodium iron sulfate is used as a sodium ion battery positive electrode material.

Classes IPC  ?

• H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
• C01G 9/00 - Composés du zinc
• H01M 10/054 - Accumulateurs à insertion ou intercalation de métaux autres que le lithium, p. ex. au magnésium ou à l'aluminium

Abrégé

A cuffless blood pressure monitoring system, which relates to the technical field of blood pressure monitoring. The system comprises: a symmetrical dual-channel PPG collection apparatus (101), a feature extraction module (102), and a blood pressure prediction model (103), wherein the symmetrical dual-channel PPG collection apparatus (101) comprises a light-emitting diode, and a first photoelectric detector and a second photoelectric detector, which are symmetrically distributed at two sides of the light-emitting diode; the symmetrical dual-channel PPG collection apparatus (101) is configured to acquire a dual-channel pulse signal; an input end of the feature extraction module (102) is connected to an output end of the symmetrical dual-channel PPG collection apparatus (101); the feature extraction module (102) is configured to extract morphological features and calculation features from the dual-channel pulse signal; an input end of the blood pressure prediction model (103) is connected to an output end of the feature extraction module (102); and the blood pressure prediction model (103) is configured to predict diastolic pressure and systolic pressure according to the morphological features and the calculation features. The symmetrical dual-channel PPG collection apparatus (101) has a small size, low cost and high sensitivity, and a non-invasive, continuous and wearable cuffless blood pressure monitoring apparatus is achieved.

Classes IPC  ?

• A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins

Abrégé

A method for manufacturing an acoustic microfluidic chip, and an acoustic microfluidic device. A phononic crystal plate and a microfluidic cavity are cleaned and then dried, and the phononic crystal plate and the microfluidic cavity are connected by means of a thin film layer to form an acoustic microfluidic chip. The present invention has strong binding force and flexible design, avoids liquid leakage, and facilitates installation.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes

Abrégé

The present invention relates to a polypeptide against alopecia and dermatitis, and a related substance and a use thereof, and in particular to a polypeptide sequence as shown in any one of SEQ ID NOs: 1-9, a polypeptide containing the sequence, or a sequence having 50% or higher homology to the sequence, and a use of their derivatives in the preparation of drugs for treating seborrheic hair follicle regression and/or alopecia, stress-induced hair follicle regression and/or alopecia, seborrheic acne and/or dermatitis, and stress-induced acne and/or dermatitis. The present invention further relates to a use of a substance, which can bind to a GPR1 receptor and exert a function, in the preparation of drugs, aesthetic medicine products, cosmetics, health care products, food, and additives for counteracting, preventing and/or treating hair follicle regression, alopecia, acne and dermatitis.

Classes IPC  ?

• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• A61K 38/09 - Hormone libérant l'hormone lutéinisante [LHRH]Peptides apparentés
• A61P 35/00 - Agents anticancéreux
• A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs

Abrégé

The present application relates to the technical field of human-computer interaction, and specifically to a holographic three-dimensional medical data visualization method and system capable of achieving mid-air gesture interaction. The method comprises the following steps: firstly, acquiring user environment information and user motion information, wherein the user environment information is image information of a real scene around a user, and the user wears a mixed reality display device; then, on the basis of the user environment information and the user motion information, generating a virtual image by using a three-dimensional interpolation volume rendering method; next, by using an optical model, projecting the virtual image into the visual field of the user, and merging the virtual image with the real scene to obtain a mixed reality rendered three-dimensional model; and finally, on the basis of the mixed reality rendered three-dimensional model, capturing a gesture of the user by using a gesture recognition method, and performing mid-air gesture interaction. The present application achieves mid-air gesture interaction between a user and a virtual scene by means of efficient three-dimensional object volume rendering and a real-time accurate interaction method design.

Classes IPC  ?

• G06F 3/04815 - Interaction s’effectuant dans un environnement basé sur des métaphores ou des objets avec un affichage tridimensionnel, p. ex. modification du point de vue de l’utilisateur par rapport à l’environnement ou l’objet
• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur

Abrégé

The present description relates to the technical field of robots, and provides a transfer robot motion planning method and apparatus, a device, and a storage medium. The method comprises: receiving a creation request for a transfer task; in response to the creation request, determining whether a transfer system currently has available transfer resources meeting the transfer task; if there are available transfer resources meeting the transfer task, allocating an exclusive target transfer resource to the transfer task, the target transfer resource comprising a position point and a transfer robot; planning a transfer path according to the position point; splitting the transfer task into a sequence of transfer sub-tasks according to the transfer path; and providing the sequence of transfer sub-tasks to the transfer robot for execution. Embodiments of the present description can reduce or avoid conflicts among a plurality of transfer tasks.

Classes IPC  ?

• B25J 9/16 - Commandes à programme

Abrégé

xyz43xyz433, wherein 1.0≤x≤3.0, 0.5≤y≤2.0, 0.5≤z≤1.5, and M is a transition metal; and the particle size of the positive electrode material is 10-80 nm. The non-destructive fast-charging positive electrode material is synthesized by means of low-temperature solvothermal, flash drying and low-temperature calcination methods, the positive electrode material can be used in a sodium ion battery, and the ultrasmall particle size of the positive electrode material is conducive to shortening the diffusion path of ions and electrons, thereby achieving fast transport of sodium ions; in addition, partial substitution of transition metal ions further improves the reaction activity of the material, thereby improving the rate performance of the material.

Classes IPC  ?

• H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
• H01M 4/136 - Électrodes à base de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFy
• H01M 10/054 - Accumulateurs à insertion ou intercalation de métaux autres que le lithium, p. ex. au magnésium ou à l'aluminium

Abrégé

The present invention relates to a dielectric elastomer-rope traction force transmission system and method for tail end direct drive force compensation. The system comprises a PC/control system, a driver, a data collection card, a precision voltage source, a sensing module, a servo electric motor, a force sensor, a dielectric elastomer driver, an anchor point, a Bowden cable and a sleeve, wherein the PC/control system is connected to the data collection card; a lead-out wire of the data collection card is respectively connected to the driver, the force sensor, the precision voltage source and the sensing module; the driver is used for controlling the servo electric motor; one side of the force sensor is connected to the servo electric motor by means of the Bowden cable, and the other side thereof is connected to the dielectric elastomer driver by means of the Bowden cable; the precision voltage source and the sensing module are both connected to a wire in the Bowden cable; and the dielectric elastomer driver is fixed to the anchor point. The dielectric elastomer-rope traction force transmission system for tail end direct drive force compensation provided in the present invention can implement precise force control in a traditional Bowden cable transmission system.

Classes IPC  ?

• B25J 9/10 - Manipulateurs à commande programmée caractérisés par des moyens pour régler la position des éléments manipulateurs
• B25J 9/00 - Manipulateurs à commande programmée

Abrégé

Disclosed in the present application are a nucleic acid purification kit and a testing device. The nucleic acid purification kit comprises: a housing assembly having an accommodating space; a liquid storage assembly located in the accommodating space and provided with a plurality of liquid storage spaces arranged in a preset direction, wherein the plurality of liquid storage spaces are configured to purify nucleic acid; a transmission assembly fixedly arranged above the liquid storage assembly and configured to drive the liquid storage assembly to move in a reciprocating manner in the preset direction; and a magnetic bar assembly located above the liquid storage assembly and configured to attract magnetic beads. The transmission assembly drives the liquid storage assembly to move in such a way that different liquid storage spaces move below the magnetic bar assembly, and the magnetic bar assembly attracts lower magnetic beads to different liquid storage spaces. In the present application, the magnetic bar assembly can attract the magnetic beads to enter and exit from the plurality of liquid storage spaces, respectively, so that nucleic acid extraction and testing can be automatically carried out, thereby facilitating the operation, achieving a stable testing result, and lowering the implementation difficulty of mass testing.

Classes IPC  ?

• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN

Abrégé

A drivable drug-release and sampling integrated capsule, which falls within the technical field of medical instruments, and can achieve targeted release of a drug of an exact dose and nearly non-invasive tissue sampling at a precise position in the human intestinal tract. The capsule comprises a shell (1), wherein the shell (1) is provided with a first external thread (11) and an internal thread (12) having the same rotation direction, and is provided with a first drug outlet at the tail and a sampling needle (4) at the head; a sleeve (2) and a plunger (3) are provided in the shell (1); the sleeve (2) is a cylinder having an opening at one end; the plunger (3) comprises a threaded section (31) and a plain shaft section (32), the threaded section (31) being provided with a second external thread (33) adapted to the internal thread (12), the plain shaft section (32) extending into the sleeve (2) and capable of axially sliding in the sleeve (2), and the bottom surface of the plain shaft section (32), the bottom surface of the sleeve (2) and the inner side wall of the sleeve (2) enclosing a drug storage cavity (5); a second drug outlet is provided in a side wall of the drug storage cavity (5); the plunger (3) can push the sleeve (2) to move in the axial direction of the shell (1); when the sleeve (2) moves to the bottom of the shell (1), the first drug outlet is in communication with the second drug outlet; and both the first external thread (11) and the second external thread (33) have magnetic properties.

Classes IPC  ?

• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
• A61B 10/02 - Instruments pour prélever des échantillons cellulaires ou pour la biopsie

Abrégé

A magnetic field vector dynamic display system capable of intelligently identifying a magnetic field type, comprising a three-dimensional magnetic field identifier (1), a data acquisition card (5), and a computer (6) which are connected in sequence. Hall sensors configured to measure a magnetic field are provided in the three-dimensional magnetic field identifier (1); an output end of the three-dimensional magnetic field identifier (1) is connected to an input end of the data acquisition card (5); an output end of the data acquisition card (5) is connected to an input end of the computer (6); the three-dimensional magnetic field identifier (1) measures the magnetic field by means of a Hall effect to obtain a magnetic field data signal and sends the magnetic field data signal to the data acquisition card (5); the data acquisition card (5) receives the magnetic field data signal and sends the magnetic field data signal to the computer (6); and the computer (6) reads the magnetic field data signal, calculates a current magnetic field type and magnetic field directions in real time, and generates a visual magnetic field direction pattern in real time. The magnetic field vector dynamic display system capable of intelligently identifying a magnetic field type can measure a three-dimensional magnetic field vector, and can also reflect magnetic field distribution and the magnetic field type.

Classes IPC  ?

• G01R 33/07 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques en utilisant des dispositifs galvano-magnétiques des dispositifs à effet Hall
• G01R 29/08 - Mesure des caractéristiques du champ électromagnétique
• G01R 33/02 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques

Abrégé

Provided are a fully synthetic yeast inducible promoter and a construction method therefor. By means of modularizing the promoter architecture, the present method splits the upstream activation region and core promoter region thereof, and uses rational design, computer model assistance and high-throughput library construction to screen spacer sequences. Promoter architecture using Saccharomyces cerevisiae as the chassis microorganism is explored, and a fully synthetic non-natural yeast inducible promoter sequence is obtained. The problems of there being an insufficient number of well-characterized promoters due to high background leakage of promoters, insufficient induction strength and limited types, or of homologous recombination in Saccharomyces cerevisiae easily occurring, are solved.

Classes IPC  ?

• C12N 15/81 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons pour levures
• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
• C12N 1/19 - LevuresLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• G16B 5/00 - TIC spécialement adaptées à la modélisation ou aux simulations dans la biologie des systèmes, p. ex. réseaux de régulation génétique, réseaux d’interaction entre protéines ou réseaux métaboliques
• G16B 20/30 - Détection de sites de liaison ou de motifs
• G16B 30/00 - TIC spécialement adaptées à l’analyse de séquences impliquant des nucléotides ou des aminoacides
• C12R 1/865 - Saccharomyces cerevisiae

Abrégé

The present application relates to the technical field of biological medicines. Provided are an enzyme kinetics parameter prediction model training method, an enzyme kinetics parameter prediction method, and a related device. The influence of environmental factors on enzyme kinetics parameters is taken into consideration during model training, thereby improving the prediction accuracy of the enzyme kinetics parameters; and a trained model is suitable for any enzyme sequence and any substrate structure, thereby improving the universality and practicability of the model.

Classes IPC  ?

• G16C 10/00 - Chimie théorique computationnelle, c.-à-d. TIC spécialement adaptées aux aspects théoriques de la chimie quantique, de la mécanique moléculaire, de la dynamique moléculaire ou similaires

Abrégé

Provided are a microfluidic cell migration phenotype-based sorting chip and a sorting method. A cell injecting port is used for injecting cells to a side edge of a main channel, a chemoattractant loading port is used for injecting a chemoattractant solution, and a culture medium loading port is used for injecting a culture medium solution. The chemoattractant loading port and the culture medium loading port are respectively communicated with one end of the main channel by means of branch channels, and the other end of the main channel is communicated with a high-migration phenotype cell outlet and a low-migration phenotype cell outlet. The high-migration phenotype cell outlet is used for collecting cells having a high migration phenotype, and the low-migration phenotype cell outlet is used for collecting cells having a low migration phenotype. By establishing a stable chemoattractant concentration gradient in a micro-channel of a chip to induce cells to migrate directionally, cells having different migration abilities have different migration distances in the channel, and then the cells having different migration phenotypes are dissociated by using a dissociation solution, and are recovered from different outlets, so that accurate directional migration of cells in a short time can be ensured, and the sorting efficiency is remarkably improved.

Classes IPC  ?

• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes

Abrégé

An enzyme kinetics parameter prediction method, and an electronic device and a storage medium. The method comprises: acquiring training samples, and using at least one re-weighting method to perform re-weighting on each category of samples among the training samples, wherein the training samples comprise target samples of a target category (S21); using the re-weighted training samples to train enzyme kinetics parameter prediction models, and using a cross validation method to determine the model prediction accuracy of a prediction model corresponding to each re-weighting method (S22); and selecting the prediction model having the highest prediction accuracy as a target model, and using the target model to perform enzyme kinetics parameter prediction on an enzyme to be subjected to prediction (S23).

Classes IPC  ?

• G16C 20/70 - Apprentissage automatique, exploration de données ou chimiométrie
• G16C 10/00 - Chimie théorique computationnelle, c.-à-d. TIC spécialement adaptées aux aspects théoriques de la chimie quantique, de la mécanique moléculaire, de la dynamique moléculaire ou similaires

Abrégé

Disclosed in the present invention are a legged-tracked composite mobile robot driving and controlling system and method. The system comprises an information collection sensor, an upper computer, a legged driving subsystem and a tracked driving subsystem, wherein after the information collection sensor acquires size information of an obstacle in a pre-specified activity area, the upper computer compares the size of the obstacle with a preset safety threshold value, so as to confirm to select a legged driving mode or a tracked driving mode, and generates a gait control instruction or a tracked driving instruction according to the size information of the obstacle; when the legged driving subsystem receives the gait control instruction sent by the upper computer, the motion of a legged driving mechanism is controlled according to the gait control instruction; and when the tracked driving subsystem receives the tracked driving instruction sent by the upper computer, the motion of a tracked driving mechanism is controlled according to the tracked driving instruction. In the present invention, the motion mode of a legged-tracked robot can be automatically switched according to the size of an obstacle, so as to adapt to a more complex operating environment.

Classes IPC  ?

• B62D 57/00 - Véhicules caractérisés par des moyens de propulsion ou de prise avec le sol autres que les roues ou les chenilles, seuls ou en complément aux roues ou aux chenilles

Abrégé

2325222O, wherein a, b, c, d and e represent mole fractions, a is 4-39, b is 5-15, 17-35, 37-53 or 55-65, c is 1-10, d is 0-60, e is 2-12, X is one or more of Ca, Mg and Sr, and Y is one or more of Na or K. In the present invention, by means of adjusting the composition of the weakly-basic borosilicate bioactive glass, a weakly-basic environment after degradation is achieved, and a hemolytic reaction caused by a highly-basic environment is significantly reduced, so that the in vitro cytocompatibility is significantly improved.

Classes IPC  ?

• A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 27/10 - Céramiques ou verres
• A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61L 27/58 - Matériaux au moins partiellement résorbables par le corps

Abrégé

A spinal cord clamp for two-photon recording, comprising a base (10) and a spinal cord clamping module (20) mounted on the base (10). The spinal cord clamping module (20) comprises a clamping member (21) and a mounting assembly (22) used for mounting the clamping member (21) on the base; the clamping member (21) comprises a first support (211) mounted on the base (10) and a second support (212) slidably provided on the first support (211); the first support (211) and the second support (212) each have clamping arms extending towards the base (10); and a spinal cord clamping space (213) is formed between the clamping arms of the first support (211) and the second support (212). The spinal cord clamp (100) has an adjustable clamping range, high clamping strength, and high structural stability and durability, and can avoid causing shaking of the field of view of two-photon microscopes and ensure good imaging quality.

Classes IPC  ?

• A61D 3/00 - Appareils pour soutenir ou ligoter les animaux à opérer
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

Disclosed in the present invention are an attack detection method and apparatus for an autonomous driving system, a device, and a storage medium. The method comprises: respectively performing target detection on three-dimensional information data and two-dimensional information data acquired by a three-dimensional sensor and a two-dimensional sensor to obtain a first three-dimensional detection bounding box and a first two-dimensional detection bounding box; performing fusion target detection on the three-dimensional information data and the two-dimensional information data to obtain a second three-dimensional detection bounding box, and performing coordinate transformation on the second three-dimensional detection bounding box to obtain a second two-dimensional detection bounding box; then performing IoU value calculation on the first two-dimensional detection bounding box and the second two-dimensional detection bounding box corresponding to each object to obtain a first array, and performing IoU value calculation on the first three-dimensional detection bounding box and the second three-dimensional detection bounding box corresponding to each object to obtain a second array; and analyzing the first array and the second array to confirm whether a sensor is attacked. The present invention can perform attack detection on the basis of multi-modal data and can locate an attacked sensor.

Classes IPC  ?

• G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
• G06V 20/56 - Contexte ou environnement de l’image à l’extérieur d’un véhicule à partir de capteurs embarqués

Abrégé

A system and method for the regulation and control of head and neck lymph. The system comprises a detection module, a data processing module, a control module, and a stimulation module, wherein the stimulation module utilizes non-invasive external stimulation of a light source to regulate and control superficial cerebral lymph, thereby promoting lymphatic drainage and enhancing the activity and functions of lymphocytes. In addition, since the action range of the light source is easy to control and the device is simple, the accuracy of the regulation and control of lymph is improved, the use cost is reduced, and the application range of the system is expanded.

Classes IPC  ?

• A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux
• A61N 5/067 - Thérapie par radiations utilisant un rayonnement lumineux utilisant un rayonnement laser
• A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire

Abrégé

An electric stimulation system and method for spinal cord injury, the system comprising: hydrogel electrodes (100), a data collector (200), a controller (300) and an electric stimulator (400). The hydrogel electrodes (100) comprise a first hydrogel electrode (110) attached to the upper cross section at a spinal cord fracture of a target subject and a second hydrogel electrode (120) attached to the lower cross section corresponding to the upper cross section. The hydrogel electrodes (100) are used for collecting electrophysiological signals of the nervous tract at the spinal cord fracture of the target subject. The data collector (200) is used for receiving the electrophysiological signals from the hydrogel electrodes (100) and converting same into corresponding electrophysiological digital signals. The controller (300) is used for performing data processing on the electrophysiological digital signals separately to obtain corresponding electric stimulation signals. The electric stimulator (400) is used for, on the basis of the electric stimulation signals, performing electric stimulation on the corresponding nervous tract by means of the hydrogel electrodes (100), so as to induce a corresponding nerve impulse to achieve a physiological function.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61N 1/04 - Électrodes

Abrégé

Provided are a protein identification method, an electronic device and a storage medium. The method comprises: acquiring a protein sequence; using a plurality of pre-trained self-supervised models to perform information extraction on the protein sequence, so as to obtain a plurality of embedded vectors of the protein sequence; according to the plurality of embedded vectors and a plurality of pre-trained classification models, generating a target probability vector of the protein sequence; and, according to a pre-trained prediction model, predicting the target probability vector to obtain a prediction result of a protein category of the protein sequence. Using the described method can improve the efficiency of identifying protein sequences.

Classes IPC  ?

• G16B 30/00 - TIC spécialement adaptées à l’analyse de séquences impliquant des nucléotides ou des aminoacides
• G16B 40/20 - Analyse de données supervisée

Abrégé

A lymph node regulation and control system and method. The system comprises a measurement module, a data processing module, a control module and a stimulation module, wherein the stimulation module utilizes non-invasive external stimulation of direct current to regulate and control superficial lymph nodes of the whole body, so as to promote the immune system to work. In addition, by means of utilizing the characteristics of easily controllable action ranges and simple equipment of electric stimulation, the present invention improves the accuracy of lymphatic regulation and control and reduces use cost, thus expanding the application range of the system.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
• A61B 5/01 - Mesure de la température de parties du corps
• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
• A61B 8/08 - Applications cliniques

Abrégé

The present description relates to the technical field of synthetic biological study, and provides a genome file data processing method and apparatus, a device, and a storage medium. The method comprises: splitting a genome file in units of specified genetic units to form a genetic unit sequence, and writing the genetic unit sequence into a genetic unit library; receiving a selection operation for one or more genetic units in the genetic unit sequence; reading the corresponding genetic unit from the genetic unit library according to the selection operation to form a genetic unit subsequence; and displaying the genetic unit subsequence. Embodiments of the present description can increase the speed of loading a genome file.

Classes IPC  ?

• G16B 20/00 - TIC spécialement adaptées à la génomique ou protéomique fonctionnelle, p. ex. corrélations génotype-phénotype

Abrégé

The present application relates to the technical field of medical treatments. Provided are an image reconstruction method and apparatus, and an electronic device and a storage medium. The method comprises: acquiring a set number of two-dimensional images of a target; performing feature coding processing on the two-dimensional images to obtain target features; acquiring a plurality of target query vectors used for locating feature points in the target features, and decoding the target features according to the target query vectors, so as to obtain grayscale information, wherein the grayscale information comprises grayscale values corresponding to locations in a reconstructed three-dimensional image; and performing image reconstruction according to the grayscale information, so as to obtain a three-dimensional image of the target. The present application solves the problems in the prior art of a large computation amount in image reconstruction and the long duration thereof.

Classes IPC  ?

• G06T 7/55 - Récupération de la profondeur ou de la forme à partir de plusieurs images
• G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie
• G06T 9/00 - Codage d'image
• G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
• G06N 3/0464 - Réseaux convolutifs [CNN, ConvNet]

Abrégé

An AAV vector and a use thereof. The AAV vector comprises a nucleic acid fragment encoding a TAT-degradation peptide. The designed AAV vector comprising a nucleic acid fragment encoding a secretory TAT-degradation peptide can be continuously expressed on the periphery, the expressed degradation peptide crossing a blood-brain barrier and a cell membrane to realize long-acting intervention of central nervous diseases, or can be continuously expressed in the central nervous system to cross the cell membrane so as to exert an effect in both AAV infected cells and non-infected cells. That is, the AAV vector achieves the wide and long-acting delivery of a degradation peptide drug.

Classes IPC  ?

• C12N 15/864 - Vecteurs parvoviraux
• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux

Abrégé

The present application relates to an indoor three-dimensional object reconstruction method and apparatus, a computer device and a storage medium. The method comprises: using a monocular camera to acquire indoor scene images under a plurality of different visual angles; inputting the indoor scene images into a trained neural radiation field model, the neural radiation field model outputting the volume density and the RGB color of each indoor scene image by means of an MLP network, and using a volume rendering algorithm to render, according to the volume density and the RGB color, a scene picture under each visual angle; and fusing the scene pictures under the plurality of different visual angles to generate three-dimensional reconstructed images of indoor scenes. The embodiments of the present application reduce the sampling times of a fitting space light field, thus reducing the time for three-dimensional reconstruction. The embodiments of the present application do not require storing a large amount of scene information, and can avoid the complex process needing manual modeling in traditional methods, thereby greatly reducing storage space and computing resources.

Classes IPC  ?

• G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie
• G06T 15/00 - Rendu d'images tridimensionnelles [3D]
• G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie

Abrégé

The present invention relates to the technical field of biological materials. Specifically disclosed are a bionic vison restoration material and a preparation method therefor, a restoration membrane and a preparation method therefor, and a restoration device. The bionic vision restoration material comprises a gel material; the gel material is a ferroelectric gel or a piezoelectric gel; the ferroelectric gel is selected from a polyacrylonitrile and/or polyacrylonitrile composite gel; the Young's modulus of the gel material is 10 Pa to 300 MPa; and an electric signal having a current density of 1 pA mm-2to 100 mA mm-2 and a voltage of 10 mV to 100 V can be generated under illumination of 200 nm to 2500 nm or ultrasonic waves having power of 1 W to 1000 W. The bionic vison restoration material of the present invention is soft, and can be adaptively attached to eyeballs or visual cortex; and under illumination or ultrasonic waves, an electric signal can be generated to stimulate visual nerve cells for vision restoration.

Classes IPC  ?

• A61L 27/16 - Matériaux macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 27/02 - Matériaux inorganiques
• A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 27/08 - Carbone
• A61L 27/20 - Polysaccharides
• A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61L 27/52 - Hydrogels ou hydrocolloïdes

Abrégé

An optical system integrating precise optogenetic stimulation and multi-channel optical signal detection and used in a fluorescence microscopy imaging device, comprising a photostimulation light source (10), a first lens (11), a galvanometer scanner (12), a second lens (13), and a first dichroic mirror (14), a third lens (15), a fourth lens (16), a second dichroic mirror (17), a first emission filter (18), a fifth lens (19), a first photomultiplier tube (20), a second emission filter (21), a sixth lens (22), and a second photomultiplier tube (23). The photostimulation light source (10) of the optical system is integrated into optical signal detection, and the optical system has the following advantages: a photostimulation optical path shares part of a detection optical path, so that optical path design is simplified, and the compact layout of the system is realized; compared with using an independent module for photostimulation, less materials are used, and the manufacturing costs are reduced; and precise focusing of photostimulation can be achieved, the working stability is improved, the operation process in a biological experiment can be simplified, and the experiment efficiency is improved.

Classes IPC  ?

• G01N 21/64 - FluorescencePhosphorescence

Abrégé

A non-contact rotating device and a modulation part manufacturing method. The non-contact rotating device comprises an ultrasonic transducer (100) and a modulation part (200); the ultrasonic transducer (100) is used for generating planar waves; the modulation part (200) is arranged on a propagation path of the planar waves, and is located between the ultrasonic transducer (100) and a target object (300); the modulation part (200) can enable the planar waves passing through the modulation part (200) to generate a phase difference so as to form a vortex sound field having multi-order topological charges, and the vortex sound field can drive the target object (300) to rotate. The non-contact rotating device has a relatively simple structure and low overall device manufacturing cost, and can be widely applied to experimental systems or industrial manufacturing. Additionally, an acoustic vortex field having multi-order topological charges can be generated, and the rotation speed of the object is controlled by adjusting the distance between the modulation part (200) and the target object (300), helping an operator to select, according to requirements, an acoustic vortex field of an appropriate order to be applied to the target object (300), so that the operation is more flexible.

Classes IPC  ?

• G10K 11/36 - Dispositifs pour transformer les ondes acoustiques de surface

Abrégé

The present invention relates to an enzyme kinetic parameter prediction method and apparatus. The method comprises: S101: using a self-supervised language model to perform training and learning of amino acid sequences of enzymes, so as to obtain an enzyme sequence representation; S102, using the self-supervised language model to perform self-supervised learning of a representation of a simplified molecular input line entry system for molecular structures, so as to obtain a molecular structure representation; S103, establishing a relationship between the enzyme sequence and molecular structure representations and enzyme kinetic parameters; and S104: on the basis of a multi-sequence alignment-based new enzyme search process, comparing a new enzyme with enzymes in a database, so as to find front pre-set number of most similar enzyme variants, and, according to the established relationship between the enzyme sequence and molecular structure representations and the enzyme kinetic parameters, carrying out kinetic parameter prediction on the front pre-set number of enzyme variants, so as to select a plurality of enzyme variants having highest enzyme kinetic parameters. The present invention can effectively accelerate enzyme screening processes.

Classes IPC  ?

• G16C 10/00 - Chimie théorique computationnelle, c.-à-d. TIC spécialement adaptées aux aspects théoriques de la chimie quantique, de la mécanique moléculaire, de la dynamique moléculaire ou similaires
• G16C 20/70 - Apprentissage automatique, exploration de données ou chimiométrie
• G16B 30/10 - Alignement de séquenceRecherche d’homologie
• G16B 40/00 - TIC spécialement adaptées aux biostatistiquesTIC spécialement adaptées à l’apprentissage automatique ou à l’exploration de données liées à la bio-informatique, p. ex. extraction de connaissances ou détection de motifs

Abrégé

Disclosed is a photo-induced pyroelectric tweezer device (10). The photo-induced pyroelectric tweezer device (10) is formed by compounding a photo-induced temperature-variable material (11) and a pyroelectric material (12). Since the photo-induced temperature-variable material (11) and the pyroelectric material (12) can output electricity and force dual signals through a photo-induced pyroelectric mechanism under illumination, non-contact remote manipulation over cells, liquid, particles, and other objects made from diffferenr material and having the scale ranging from nanometer to centimeter is achieved. According to a manipulation system and a manipulation method based on the photo-induced pyroelectric tweezer device (10), optical manipulation is achieved through multi-field coupling of light, heat and electric fields, and compared with classic optical tweezer manipulation techniques and systems, the light field intensity required by optical manipulation is reduced, applied force which can be generated is improved, the scale of the manipulated objects is expanded, and manipulation over objects ranging from microscale ones to macroscale ones can be realized with the remote and non-contact manipulation property, high resolution and high flexibility of original optical tweezer manipulation maintained, and thus the application potential is extensive.

Classes IPC  ?

• G21K 1/00 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p. ex. pour focaliser ou pour modérer

Abrégé

A medical wastewater treatment device based on cavitation plasma technology, the device comprising a plasma generation source (2), a booster pump (5) and a cavitation plasma generator (7), wherein the cavitation plasma generator (7) has a tubular structure, and an inlet section, a converging section, a throat and a diverging section are sequentially connected inside the tubular structure; two metal discharge electrodes (72) are provided on the side wall of the tubular structure corresponding to the throat or the diverging section, and are arranged opposite each other; insulating layers are provided between the metal discharge electrodes (72) and the side wall of the tubular structure; the plasma generation source (2) is connected to the two metal discharge electrodes (72), and is used for generating a high-frequency pulsed current; and an outlet of the booster pump is connected to the inlet section of the cavitation plasma generator (7).

Classes IPC  ?

• C02F 1/30 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par irradiation

Abrégé

Disclosed in the present invention are a semantic segmentation-based unmanned aerial vehicle image georeferencing method, and a related device. In the present invention, adding road semantic constraints to focus areas of concern for feature extraction on a road area can effectively reduce redundant features and improve feature matching efficiency, screening matched feature point pairs in a feature matching stage can effectively eliminate mismatching, so as to improve image registration precision, and a pixel corresponding relationship between an unmanned aerial vehicle image and a reference image, which is obtained by means of feature matching, and a mapping relationship between pixel coordinates of the reference image and geographic coordinates can be combined to finally solve geographic coordinates of the unmanned aerial vehicle image, thus achieving high-precision unmanned aerial vehicle image georeferencing.

Classes IPC  ?

• G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
• G06V 10/26 - Segmentation de formes dans le champ d’imageDécoupage ou fusion d’éléments d’image visant à établir la région de motif, p. ex. techniques de regroupementDétection d’occlusion

Abrégé

x3-0.5x43x3-0.5x433@C positive electrode material has advantages such as high purity, excellent electrical conductivity, a stable structure, high reversible capacity, high coulombic efficiency, and excellent cycle performance. The preparation method is energy-saving, environment-friendly and efficient, is easy to operate and has low equipment requirements, has abundant, low-cost raw materials, and is suitable for large-scale industrial production.

Classes IPC  ?

• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
• H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
• H01M 10/054 - Accumulateurs à insertion ou intercalation de métaux autres que le lithium, p. ex. au magnésium ou à l'aluminium

Abrégé

ggg is very small, and the dispersion and interface problems of an inorganic filler are avoided.

Classes IPC  ?

• C08G 75/23 - Polyéthersulfones
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08L 79/08 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
• C08L 81/06 - PolysulfonesPolyéthersulfones

Abrégé

Provided are an oxidative stress inducer for triple-negative breast cancer cells and a pharmaceutical composition for synergistically resisting triple-negative breast cancer. The active ingredients of the oxidative stress inducer for triple-negative breast cancer cells include brusatol and polydatin. The active ingredients of the pharmaceutical composition for synergistically resisting triple-negative breast cancer include brusatol and polydatin. Polydatin and brusatol feature good treatment efficacy and low toxicity in synergistically resisting triple-negative breast cancer.

Classes IPC  ?

• A61K 31/7034 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine
• A61K 31/366 - Lactones ayant des cycles à six chaînons, p. ex. delta-lactones
• A61P 35/00 - Agents anticancéreux
• A61P 15/14 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs pour les troubles de la lactation, p. ex. galactorrhée

Abrégé

Disclosed in the present invention are a pedestrian geographic trajectory extraction method and device. The method comprises: acquiring unmanned aerial vehicle images corresponding to an unmanned aerial vehicle video, and identifying a target pedestrian in the unmanned aerial vehicle images by using an object detection algorithm; performing pixel trajectory extraction on the identified target pedestrian by using a multi-object tracking algorithm, so as to obtain a pedestrian pixel trajectory; identifying geographic coordinates in the unmanned aerial vehicle images by using an image registration algorithm, so as to obtain a mapping relationship between pixel coordinates of the unmanned aerial vehicle images and the geographic coordinates of the unmanned aerial vehicle images; and obtaining a pedestrian geographic trajectory on the basis of the mapping relationship between the pixel coordinates of the unmanned aerial vehicle and the geographic coordinates of the unmanned aerial vehicle, and the pedestrian pixel trajectory. In the pedestrian geographic trajectory extraction method disclosed in the present embodiments, images are accurately located by means of a geographic registration technique, thereby achieving higher trajectory extraction accuracy. Moreover, compared with trajectory extraction methods based on devices such as a GPS, the pedestrian geographic trajectory extraction method in the present invention is not affected by factors such as signal shielding, and can achieve real-time pedestrian geographic trajectory extraction.

Classes IPC  ?

• G06V 40/10 - Corps d’êtres humains ou d’animaux, p. ex. occupants de véhicules automobiles ou piétonsParties du corps, p. ex. mains
• G06V 20/17 - Scènes terrestres transmises par des avions ou des drones
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
• G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
• G06V 10/74 - Appariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques
• G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
• G06T 7/10 - DécoupageDétection de bords

Abrégé

Disclosed in the present invention are polypeptides and related substances against hair loss and dermatitis, and the uses thereof. Particularly, disclosed is the use of an osteocalcin-derived peptide, and homologous polypeptides, polypeptide-derived peptides or derivatives of the polypeptides and polypeptide-derived peptides, which use the osteocalcin-derived peptide as a skeleton and which are derived from different species, in preparing drugs for treating hair follicle recession and/or hair loss caused by stress, seborrheic hair follicle recession and/or hair loss, acne and/or dermatitis caused by stress and seborrheic acne and/or dermatitis. Further disclosed are the use, in preparing drugs, medical cosmetology products, cosmetics, health-care products, foods and additives for preventing and/or treating hair follicle recession, hair loss, acnes and dermatitis, of substances capable of binding to GPR158 receptor and achieving functions, and a method for preparing a related hair loss model on the basis of the discovery of the GPR158 receptor.

Classes IPC  ?

• C07K 14/575 - Hormones
• C07K 7/00 - Peptides ayant de 5 à 20 amino-acides dans une séquence entièrement déterminéeLeurs dérivés
• A61K 38/22 - Hormones
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61Q 7/00 - Préparations pour modifier la pousse des cheveux ou des poils
• A61P 17/10 - Antiacnéïques
• A61P 17/14 - Médicaments pour le traitement des troubles dermatologiques pour le traitement de la calvitie ou de l'alopécie

Abrégé

Disclosed are a self-supporting positive electrode and a preparation method therefor and the use thereof, which belong to the technical field of secondary battery materials. The self-supporting positive electrode comprises a conductive carrier and sodium iron sulfate nanoparticles loaded on the conductive carrier, and when the self-supporting positive electrode is used in a sodium-ion battery, the energy density, power density, rate performance and cycle performance of the sodium-ion battery can be effectively improved.

Classes IPC  ?

• H01M 4/136 - Électrodes à base de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFy
• H01M 4/1397 - Procédés de fabrication d’électrodes à base de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFy
• H01M 10/054 - Accumulateurs à insertion ou intercalation de métaux autres que le lithium, p. ex. au magnésium ou à l'aluminium
• H01M 4/04 - Procédés de fabrication en général

Abrégé

Disclosed are a magnetic digital microfluidic system and a microfluidic method. The system comprises a droplet manipulation unit, a magnetic core coil array on-off unit, a logic control unit, and a signal detection unit. The droplet manipulation unit comprises a microfluidic platform and a magnetic core coil array. The magnetic core coil array is arranged below the microfluidic platform and is connected to the magnetic core coil array on-off unit. The logic control unit is separately connected to the magnetic core coil array on-off unit and the signal detection unit. By means of the magnetic core coil array, the present invention can directly drive magnetic droplets and non-magnetic droplets in the microfluidic platform, and achieve control over the droplets and a series of operations such as transport, merging, distribution, heating and detection on the droplets, such that the problems that existing magnetic digital microfluidic systems are restricted to driving only magnetic droplets and have poor biocompatibility can be solved.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes

Abrégé

A method and apparatus for functional safety testing under a transient fault of a chip, and a device. The method comprises: during transient fault simulation testing of a chip, acquiring a set of hit functional units and a corresponding set of test patterns when the functional units are hit; sorting the set of test patterns into a test pattern sequence on the basis of contribution degree and coverage with respect to the set of functional units; controlling a radiation source to continuously radiate the chip; sequentially inputting each test pattern in the test pattern sequence into the chip in batches, and detecting fault detection results of the functional units in each input; and determining a functional testing result of the chip in each input according to the fault detection results of the functional units in each input. In this way, the testing efficiency of functional safety testing of a chip under a transient fault can be improved.

Classes IPC  ?

• G06F 11/263 - Génération de signaux d'entrée de test, p. ex. vecteurs, formes ou séquences de test
• G06F 11/273 - Matériel de test, c.-à-d. circuits de traitement de signaux de sortie

Abrégé

Disclosed in the present invention is an end-to-end text recognition method. The method comprises: obtaining a text picture to be recognized; and inputting the text picture to a trained text recognition model to obtain a text recognition result. The text recognition model comprises a feature extraction network, a text detection branch, and a word recognition branch. The feature extraction network is configured to extract a text candidate feature and a word candidate feature. The text detection branch predicts a text bounding box on the basis of the text candidate feature. The word recognition branch predicts a bounding box and word content of a word by performing key point detection on the word candidate feature. The text recognition result is obtained by combining words that fall within the text bounding box. According to the present invention, the robustness of text recognition is improved, text content in a variety of scenarios can be accurately recognized, and the method is particularly suitable for scenarios with font diversity.

Classes IPC  ?

• G06V 20/62 - Texte, p. ex. plaques d’immatriculation, textes superposés ou légendes des images de télévision
• G06V 30/18 - Extraction d’éléments ou de caractéristiques de l’image

Abrégé

Provided are an orthodontic force measuring device and method. The measuring device comprises an occlusion fixing part (20) and a measuring part (10). The occlusion fixing part (20) can be fitted to teeth of a patient; the measuring part (10) can slide on the occlusion fixing part (20); and when the measuring part (10) slides to the position corresponding to a tooth under measurement, the position of the measuring part (10) is controlled to be fixed, so as to load displacement on the tooth and measure orthodontic force. Therefore, the effective and fixed connection between the measuring part (10) and the patient can be implemented in the orthodontic force measuring process, and an error of displacement loading is smaller, so that the obtained measurement result is more accurate.

Classes IPC  ?

• A61C 19/04 - Instruments de mesure spécialement adaptés à la technique dentaire
• A61C 19/05 - Instruments de mesure spécialement adaptés à la technique dentaire pour déterminer l'occlusion
• A61C 7/08 - Appareils de contention du type épousant la forme de la bouche

Abrégé

The present application provides an interactive nucleus segmentation method combining a Voronoi contour and a weighted convex difference. The method comprises: acquiring a pathological image, and labeling a labeling point on the pathological image; using the labeling point as prior information to construct a Voronoi contour; inputting the Voronoi contour as an initial contour into a pre-constructed weighted convex difference model, so as to obtain an initial segmentation result; and selecting a final segmentation result according to the initial segmentation result. The segmentation method is more accurate in terms of segmentation.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• G06T 7/10 - DécoupageDétection de bords
• G06T 7/12 - Découpage basé sur les bords

Abrégé

The present application relates to a robot remote control method and a system. The method comprises: acquiring gesture data of an operator by means of a detection device; projecting and mapping the gesture data into Unity, and displaying a gesture image by means of a VR operating system interface; and identifying, according to a preset mode parameter, an operation mode corresponding to the gesture image, and remotely controlling, according to the operation mode, a robot to make a corresponding operation action. The present application solves the problems of perception error caused by the back of the hand shielding the fingers when a Leapmotion device is mounted on the head and used, and the like, gesture recognition and remote control operations can be completed simply by means of a simple one-handed gesture, excessive gesture training does not need to be carried out, and the operation is simpler.

Classes IPC  ?

• H04L 67/125 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p. ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance en impliquant la commande des applications des terminaux par un réseau

Abrégé

Disclosed in the present invention is a deformable object simulation method for robotic manipulation. The method comprises: selecting a plurality of feature points from a mesh model of a deformable object, wherein the mesh model of the deformable object comprises meshes and mesh nodes; on the basis of a skin weight method, establishing a mapping relationship between a pose of each feature point and a displacement of each mesh node of the deformable object; on the basis of the mapping relationship, establishing a low-order subspace for object deformation, and establishing a dynamics system equation of the mesh nodes of the deformable object in the low-order subspace; calculating an elastic force on the mesh nodes of the deformable object, and solving for the dynamics system equation to obtain deformation information of the mesh model of the deformable object at multiple consecutive moments; and when the deformable object is manipulated by a robot to deform, mapping an operating pose of an end effector into deformation of the meshes of the deformable object. The present invention improves the calculation efficiency of deformation information of the deformable object.

Classes IPC  ?

• G06T 17/20 - Description filaire, p. ex. polygonalisation ou tessellation
• G06T 17/10 - Description de volumes, p. ex. de cylindres, de cubes ou utilisant la GSC [géométrie solide constructive]
• G06T 1/00 - Traitement de données d'image, d'application générale
• G06F 17/10 - Opérations mathématiques complexes
• G06F 17/11 - Opérations mathématiques complexes pour la résolution d'équations
• G06F 17/16 - Calcul de matrice ou de vecteur

Abrégé

Disclosed in the present invention are a calligraphy copying method and apparatus for an intelligent robot, and a device and a storage medium. The method comprises: photographing, in real time, a writing process of calligraphy by using a preset camera, so as to obtain a writing image; sequentially recognizing and segmenting, by using a pre-trained image recognition model and according to an acquisition sequence, a calligraphy writing area in each frame of writing image, so as to obtain a target feature image; sequentially extracting a calligraphic style feature from each frame of target feature image, and performing analysis according to the calligraphic style feature to obtain three-dimensional coordinates of a motion trajectory of an end effector of a robot; and on the basis of inverse kinematics, sequentially determining a motion control parameter of a robotic arm of the robot according to each set of three-dimensional coordinates, and according to the motion control parameter, controlling the robot to copy calligraphy. In the present invention, a writing image of calligraphy is photographed in real time, a calligraphic feature is extracted from the writing image, and according to the calligraphic feature, a robot is controlled to copy the calligraphy in real time.

Classes IPC  ?

• G06T 5/00 - Amélioration ou restauration d'image
• G06N 3/04 - Architecture, p. ex. topologie d'interconnexion

Abrégé

Disclosed in the present invention are a teleoperation method and apparatus for a collaborative robot, a device, and a storage medium. The method comprises: capturing a human body image of a target person in real time by using a pre-calibrated camera, and reconstructing a three-dimensional attitude image of the target person according to the human body image; and acquiring from the three-dimensional attitude image real-time attitude information of a plurality of pre-defined human body joint points, and synchronously mapping the real-time attitude information to a collaborative robot. According to the present invention, the three-dimensional attitude image of the person is reconstructed according to the human body image captured by the camera, the attitude information is acquired from the three-dimensional attitude image, and then the attitude information is synchronized to the collaborative robot, so that the objective of synchronously controlling the collaborative robot is achieved; and the attitude of the human body can be mapped to the collaborative robot, so that users can flexibly control the action of the collaborative robot in an unstructured environment.

Classes IPC  ?

• B25J 9/16 - Commandes à programme

Abrégé

The present application relates to a visual SLAM method and apparatus for an indoor environment, a device, and a storage medium. The method comprises: acquiring an RGB image of an indoor environment, and acquiring semantic information of the RGB image; extracting point and line features of the RGB image, and matching the point and line features to obtain a visual constraint of the RGB image; detecting a planar object in the RGB image on the basis of the semantic information of the RGB image, and acquiring a Manhattan world constraint of the RGB image; and performing inter-frame pose estimation on the RGB image on the basis of the visual constraint and the Manhattan world constraint, and constructing visual SLAM of the indoor environment according to an inter-frame pose estimation result. According to embodiments of the present application, the visual SLAM of the indoor environment is constructed by adding a geometric constraint of the indoor environment and combining low-level geometric features of points, lines and surfaces and high-level semantic features, thereby improving the pose estimation accuracy and robustness of a camera.

Classes IPC  ?

• G06V 20/10 - Scènes terrestres
• G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques

Abrégé

23222255.

Classes IPC  ?

• C03C 3/064 - Compositions pour la fabrication du verre contenant de la silice avec moins de 40% en poids de silice contenant du bore
• A61K 33/22 - Composés du bore
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
• A61K 9/06 - OnguentsExcipients pour ceux-ci
• A61K 47/06 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite
• A61L 27/10 - Céramiques ou verres