Provided is an oral composition comprising an L-ascorbic acid dl-α-tocopherol phosphoric acid diester alkali metal salt. The composition according to the present disclosure is capable of suppressing disruption of the oral mucosal epithelial barrier function and/or inhibiting the activity of matrix metalloproteinases (MMPs). Thus, the composition according to the present disclosure is capable of preventing the onset of periodontal disease and/or suppressing the progression of periodontal disease.
A61K 31/375 - Acide ascorbique, c.-à-d. vitamine CSes sels
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61K 47/24 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant des atomes autres que des atomes de carbone, d'hydrogène, d'oxygène, d'halogènes, d'azote ou de soufre, p. ex. cyclométhicone ou phospholipides
A61P 1/02 - Préparations stomatologiques, p. ex. médicaments pour le traitement des caries, des aphtes, des périodontites
An oral composition and a dentin protective agent according to the present disclosure are characterized by containing calcium silicate having an Si/Ca ratio of 1.15 to 2.3.
A61K 33/06 - Aluminium, calcium ou magnésiumLeurs composés
A61P 1/02 - Préparations stomatologiques, p. ex. médicaments pour le traitement des caries, des aphtes, des périodontites
A61Q 11/00 - Préparations pour le nettoyage des dents, de la bouche ou des prothèses dentaires, p. ex. dentifricesBains de bouche
3.
ORAL CAVITY STATE ANALYSIS SYSTEM, ORAL CAVITY STATE ANALYSIS PROGRAM, STORAGE MEDIUM FOR STORING ORAL CAVITY STATE ANALYSIS PROGRAM, AND ORAL CAVITY STATE ANALYSIS METHOD
[Problem] To provide an oral cavity state analysis system and an oral cavity state analysis program for analyzing the oral cavity state, the system and program making it possible to easily acquire an oral cavity image suitable for analyzing the oral cavity state. [Solution] The present invention comprises: a video reception unit 251 that continuously receives, as input from an imaging unit 21 of a user terminal 2, a facial image V of a user U captured by the imaging unit 21; an image detection unit 252 that detects a mouth image F from the facial image V; a teeth detection unit 253 that detects a teeth area TA in the mouth image F; a gum detection unit 254 that detects a gum area GA in the mouth image F; a determination unit 256 that determines whether at least one of the teeth area TA and the gum area GA included in the mouth image F satisfies a prescribed condition; an image acquisition unit 257 that acquires a single or a plurality of mouth images F determined by the determination unit 256 to satisfy the condition; and an analysis unit 258 that analyzes the oral cavity state on the basis of the mouth image F acquired by the image acquisition unit 257.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 1/24 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour la bouche, c.-à-d. stomatoscopes, p. ex. portant des abaisse-langueInstruments pour ouvrir la bouche ou la maintenir ouverte
[Problem] To provide a toothbrush with improved operability in the oral cavity through reduction of collision with the inner wall of the oral cavity caused when the toothbrush is inserted deep into the oral cavity. [Solution] A toothbrush 1 according to the present invention includes: a head portion 2 in which a plurality of brush bristle bundles 3 are each implanted at a right angle with respect to an implantation surface 20; a neck portion 5 connected to the head portion 2; and a grip portion 7 connected to the neck portion 2. The head portion 2 is composed of a base end side portion 21 extending in a longitudinal direction from a tip end of the neck portion 5, and a tip end side portion 23 extending in a longitudinal direction from a tip end of the base end side portion 21 via a step. The tip end side portion 23 is inclined in a bristle tip direction in which the brush bristle bundles 3 extend.
Provided is a technique for enabling metabolism activation. More specifically, provided is a composition for activating mitochondria, the composition containing a specific component.
A61K 8/44 - Acides aminocarboxyliques ou leurs dérivés, p. ex. acides aminocarboxyliques contenant du soufreLeurs sels, esters ou dérivés N-acylés
A61K 8/46 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant du soufre
A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
A61K 31/047 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates ayant plusieurs groupes hydroxyle, p. ex. sorbitol
A61K 31/197 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino les groupes amino et carboxyle étant liés à la même chaîne carbone acyclique, p. ex. acide gamma-aminobutyrique [GABA], bêta-alanine, acide epsilon-aminocaproïque ou acide pantothénique
A61K 31/198 - Alpha-amino-acides, p. ex. alanine ou acide édétique [EDTA]
A61K 31/7032 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un polyol, c.-à-d. composés ayant plusieurs groupes hydroxyle, libres ou estérifiés, y compris le groupe hydroxyle impliqué dans la liaison glycosidique, p. ex. monoglucosyl-diacylglycérides, acide lactobionique, gangliosides
A61K 36/28 - Asteraceae ou Compositae (famille de l'aster ou du tournesol), p. ex. camomille, chrysanthème matricaire, achillée ou echinacée
A61K 36/46 - Eucommiaceae (famille de l'eucomia), p. ex. gutta percha
A61K 36/53 - Lamiaceae ou Labiatae (famille de la menthe), p. ex. thym, romarin ou lavande
A61K 36/54 - Lauraceae (famille du laurier), p. ex. cannelle ou sassafras
A61K 36/63 - Oleaceae (famille de l'olive), p. ex. jasmin, lilas ou frêne
A61K 36/64 - Orobanchaceae (famille de l'orobranche)
A61K 36/65 - Paeoniaceae (famille de la pivoine), p. ex. pivoine chinoise
A61K 36/82 - Theaceae (famille du théier), p. ex. camélia
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61P 1/02 - Préparations stomatologiques, p. ex. médicaments pour le traitement des caries, des aphtes, des périodontites
A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
A61P 19/10 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget de l'ostéoporose
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
A61Q 11/00 - Préparations pour le nettoyage des dents, de la bouche ou des prothèses dentaires, p. ex. dentifricesBains de bouche
C07K 14/46 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés
Provided is an oral composition containing a specific sugar, an amino acid and citric acid and/or an analog thereof. The specific sugar is a polysaccharide containing, as constituent sugars, a single galactose and one or a plural number of sugars other than galactose. The citric acid and/or an analog thereof is at least one selected from citric acid and citric acid salts. The content of the specific sugar is 0.5-5 mass% inclusive. The content of the amino acid is 0.5-4 mass% inclusive. The content of the citric acid and/or an analog thereof is 0.001-2 mass% inclusive.
The anti-influenza virus composition for the throat contains as active ingredients a quaternary ammonium salt and at least one selected from isoprene, geraniol, menthol, limonene, thymol, cineole, bisabolol, borneol, camphor, and glycyrrhizin.
A61K 31/045 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates
A61K 31/125 - CamphreSes dérivés substitués sur le cycle
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
8.
Oral Condition Evaluation System, Oral Care Recommendation System, and Oral Condition Notification System
An oral state evaluation system includes an information acquisition unit and an information analysis unit. The information acquisition unit acquires an oral cavity image including at least a first specific site in the oral cavity from the interface unit as input information. The information analysis unit analyzes the state of the first specific site based on the input information. The information analysis unit estimates the estimation information regarding the state of the second specific site in the oral cavity different from the first specific site from the analysis information of the state of the first specific site.
Provided is a composition for oral use, the composition containing a dl-α-tocopherol 2-L-ascorbic acid phosphoric acid diester alkali metal salt. The composition of the present disclosure suppresses the destruction of the oral mucosa epithelial barrier function and/or can inhibit activity of matrix metalloprotease (MMP). The present invention can therefore prevent the onset and/or suppress the progression of periodontal disease.
In an interdental cleaning tool, a flexible cleaning portion including a core covering portion that covers a core base, and a plurality of recesses that are formed due to hold pins during insert molding. The recesses are formed along a longitudinal direction of the core base portion. A core base exposed portion of each recess has a shape elongated in an oblique direction that intersects both the longitudinal direction and a lateral direction orthogonal to the longitudinal direction, and, at a position where a dimension of the core base exposed portion in the longitudinal direction is maximum, the maximum dimension is 0.25 mm or less.
A molded article (20) for an oral care product includes a primary molded part (P) that includes a covering target part (PC), a secondary molded part (Q) that includes a covering part (Q40) covering the covering target part (PC), and an exposed structure (500) that includes one or a plurality of penetration parts (P100) penetrating the covering part (Q40). The penetration part (P100) includes an exposed surface exposed with respect to the covering part (Q40). The penetration part (P100) is provided in the primary molded part (P) such that a force received by the primary molded part (P) from a resin material corresponding to the secondary molded part (Q) so as to deform the primary molded part (P) in a secondary molding step of molding the secondary molded part (Q) is able to be transferred to a mold through the exposed surface.
The present invention provides a composition for suppressing the formation and maturation of plaque on tooth surfaces. More specifically, the present invention provides a composition that contains dodecylpyridinium chloride and at least one compound selected from the group that consists of citric acid and salts thereof and glycyrrhizic acid and salts thereof.
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61K 31/4425 - Dérivés de pyridinium, p. ex. pralidoxime, pyridostigmine
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
A61K 47/12 - Acides carboxyliquesLeurs sels ou anhydrides
A61P 1/02 - Préparations stomatologiques, p. ex. médicaments pour le traitement des caries, des aphtes, des périodontites
The present invention provides a liquid composition for oral cavity with good feeling of use, the liquid composition containing lauryl pyridinium chloride and cetylpyridinium chloride without deteriorating the feeling of use due to the sweetness derived from a sweetener, while suppressing the bitterness due to those chloride components. More specifically, the present invention provides the following liquid composition for oral cavity. A liquid composition for oral cavity which contains 0.01% by mass to 0.1% by mass of (A) cetylpyridinium chloride, 0.01% by mass to 0.1% by mass of (B) lauryl pyridinium chloride, 0.05% by mass to 0.2% by mass of (C) methyl parahydroxybenzoate, 0.002% by mass to 0.02% by mass of (D) saccharin sodium, and 0.01% by mass or more of (E) menthol, while satisfying one of the following requirements (i) and (ii). (i) The content of menthol is 0.01% by mass to 0.05% by mass. (ii) This liquid composition for oral cavity additionally contains 0.002% by mass to 0.02% by mass of (F) a stevia-based sweetener.
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
Provided are moving image obtaining means that obtains a moving image of a region including at least a mouth or a peripheral portion of the mouth in a face, analysis means that analyzes a chewing action based on the moving image of the region obtained by the moving image obtaining means, quality determination means that determines quality of the chewing action based on information of the chewing action analyzed by the analysis means, and extraction means that extracts assistance information corresponding to the chewing quality determined by the quality determination means, from chewing information storage means.
Provided are chewing information storage means that stores information about chewing quality, muscle activity obtaining means that obtains a muscle activity signal of masticatory muscle of a person, analysis means that frequency-analyzes the muscle activity signal obtained by the muscle activity obtaining means, and analyzes chewing behavior based on the frequency-analyzed muscle activity signal, quality determination means determines quality of the chewing behavior based on information of the chewing behavior analyzed by the analysis means, and extraction means that extracts assistance information corresponding to the chewing quality determined by the quality determination means, from chewing information storage means.
A toothbrush includes the head portion that is molded from a polyacetal resin having a weight-average molecular weight of 130000 or more. When the head portion is a thin head having a thickness of 3.0 mm or less, a base thickness that corresponds to a thickness of an implantation base is T1 (mm), a hole depth of an implantation hole is U1 (mm), a flat wire implantation depth that corresponds to a depth from an implantation face to an upper end of the flat wire implanted from the implantation face is H1 (mm), and a weight-average molecular weight of the polyacetal resin is Mw, a following equation (1) is satisfied.
A toothbrush includes the head portion that is molded from a polyacetal resin having a weight-average molecular weight of 130000 or more. When the head portion is a thin head having a thickness of 3.0 mm or less, a base thickness that corresponds to a thickness of an implantation base is T1 (mm), a hole depth of an implantation hole is U1 (mm), a flat wire implantation depth that corresponds to a depth from an implantation face to an upper end of the flat wire implanted from the implantation face is H1 (mm), and a weight-average molecular weight of the polyacetal resin is Mw, a following equation (1) is satisfied.
[Formula 1]
A toothbrush includes the head portion that is molded from a polyacetal resin having a weight-average molecular weight of 130000 or more. When the head portion is a thin head having a thickness of 3.0 mm or less, a base thickness that corresponds to a thickness of an implantation base is T1 (mm), a hole depth of an implantation hole is U1 (mm), a flat wire implantation depth that corresponds to a depth from an implantation face to an upper end of the flat wire implanted from the implantation face is H1 (mm), and a weight-average molecular weight of the polyacetal resin is Mw, a following equation (1) is satisfied.
[Formula 1]
(−18.5)+T1×7.0+U1×3.5+H1×(−10.0)+MW×0.78×10−5≥2.96 (1)
A46B 3/16 - Brosses caractérisées par la façon dont les soies sont fixées ou assemblées dans ou sur le corps ou la monture de la brosse au moyen de fil métallique ou par d'autres moyens d'ancrage, notamment pour les touffes de soies en U
A46B 9/04 - Position ou disposition des soies par rapport à la surface de la monture, p. ex. inclinées, en rangées, en groupes pour les brosses à dents
17.
ORAL CONDITION EVALUATION SYSTEM, ORAL CARE RECOMMENDATION SYSTEM, AND ORAL CONDITION NOTIFICATION SYSTEM
This oral condition evaluation system includes an information acquisition unit and an information analysis unit. At a minimum, the information acquisition unit acquires, as input information, an oral image including a first specific part in the oral cavity from an interface unit. The information analysis unit analyzes the condition of the first specific part on the basis of the input information. The information analysis unit estimates, from analysis information regarding the condition of the first specific part, estimation information relating to the condition of a second specific part in the oral cavity different from the first specific part.
A61B 1/24 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour la bouche, c.-à-d. stomatoscopes, p. ex. portant des abaisse-langueInstruments pour ouvrir la bouche ou la maintenir ouverte
A61C 19/04 - Instruments de mesure spécialement adaptés à la technique dentaire
A61C 19/06 - Appareils ou dispositifs pour traitement thérapeutique
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
Provided is an oral composition that has excellent stability over time although a hydrocarbon oil is contained therein. Specifically provided is an oral composition comprising a hydrocarbon oil, a polyhydric alcohol, and a surfactant, the oral composition comprising (1) glycerol, and a polyglycerol fatty acid ester and/or an alkyl glucoside, (ii) propanediol, and a polyoxyethylene hardened castor oil and/or a polyoxyethylene hardened castor oil fatty acid ester, (iii) butylene glycol, and a polyoxyethylene alkyl ether and/or a polyoxyethylene hardened castor oil fatty acid ester, or (iv) polyethylene glycol and a polyoxyethylene hardened castor oil fatty acid ester.
A pharmaceutical composition having consistently a desirable release rate is prepared by controlling the finally mixing time based on the molecular weight measured in the intermediate product. The pharmaceutical composition includes micro particles containing a polyhydric alcohol, a salt, a water-soluble polymer and a pharmaceutically active ingredient. The micro particles are dispersed in a matrix of a hydrophobic ingredient and an amphipathic ingredient.
The present invention is provided with: a chewing information storage means (31b) for storing information relating to the quality of chewing; a muscular activity acquisition means (21) for acquiring a muscular activity signal from a human masticatory muscle; an analysis means (22) for subjecting the muscular activity signal, acquired by the muscular activity acquisition means, to frequency analysis and analyzing a chewing mode on the basis thereof; a quality determination means (23) for determining the quality of the chewing mode on the basis of information about the chewing mode analyzed by the analysis means; and an extraction means (24) for extracting, from the chewing information storage means (32), assistance information corresponding to the quality of chewing determined by the quality determination means.
[Problem] To provide a chewing support system capable of acquiring the quality of chewing during a meal and capable of supporting improvements in the quality of chewing, and in maintenance of and improvements to health, using a simple method, without imparting a feeling of discomfort to the user or burdening the user, and without attaching equipment such as an electromyograph to the body. [Solution] This chewing support system is provided with: a moving image acquiring means (21) for acquiring a moving image of a region of the face including at least the mouth or the area around the mouth; an analyzing means (22) for analyzing the chewing action on the basis of the moving image of the region acquired by the moving image acquiring means; a quality determining means (23) for determining the quality of the chewing action on the basis of information relating to the chewing action analyzed by the analyzing means; and an extracting means (24) for extracting, from a chewing information storage means (32), support information corresponding to the quality of the chewing determined by the quality determining means.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
[Problem] To provide a toothbrush with which base cracking and appearance defects can be suppressed while the pull-out strength of bristle bundles is maintained, and with which a further reduction in the thickness of a head portion can be achieved. [Solution] This toothbrush is characterized in that a head portion is a thin head having a thickness of 3.0 mm or less formed from polyacetal resin having a weight-average molecular weight at least equal to 130,000, and in that formula (1) is satisfied, where T1 (mm) is a base thickness, which is the thickness of a bristle implanting base, U1 (mm) is the hole depth of bristle implanting holes, H1 (mm) is an anchor wire drive depth, which is the depth from the bristle implanting surface to the upper edge of an anchor wire that has been driven in, and Mw is the weight-average molecular weight of the polyacetal resin.
A46B 5/00 - Montures de brossesManches faisant corps avec la brosse
A46B 3/16 - Brosses caractérisées par la façon dont les soies sont fixées ou assemblées dans ou sur le corps ou la monture de la brosse au moyen de fil métallique ou par d'autres moyens d'ancrage, notamment pour les touffes de soies en U
A46B 9/04 - Position ou disposition des soies par rapport à la surface de la monture, p. ex. inclinées, en rangées, en groupes pour les brosses à dents
23.
PROCESS FOR PRODUCING A PHARMACEUTICAL COMPOSITION CONTAINING MICRO PARTICLES
A pharmaceutical composition having consistently a desirable release rate is prepared by controlling the finally mixing time based on the molecular weight measured in the intermediate product. The pharmaceutical composition includes micro particles containing a polyhydric alcohol, a salt, a water-soluble polymer and a pharmaceutically active ingredient. The micro particles are dispersed in a matrix of a hydrophobic ingredient and an amphipathic ingredient.
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61K 47/14 - Esters d’acides carboxyliques, p. ex. acides gras monoglycérides, triglycérides à chaine moyenne, parabènes ou esters d’acide gras de PEG
A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
(1) Interior, exterior, and house paints; Paints for automobiles and other land vehicles; Non-stick coatings in the nature of paints; Anti-rust coatings in the form of paints for use in the automotive industry; Preservatives against rust and against deterioration of wood; Raw natural resins; Anti-rust greases; Sandarac; Precious metals in foil and powder form for painters, decorators, printers and artists; Paint primers; Undercoatings for vehicle chassis; Wood preservatives
The objective of the present invention is to provide an interdental cleaning tool with which recessed portions left as marks of holding pins during insert molding do not readily cause peeling of soft portions for cleaning, as a result of being caught on the teeth or on tartar when cleaning between the teeth, and with which, even if peeling does occur, a large amount of peeling can be avoided, and re-peeling from the end portion after peeling can also be prevented. A soft portion (21) for cleaning includes a core covering portion (21a) covering a core base material portion (12), and a plurality of recessed portions (21c), which are recessed portions formed by holding pins during insert molding, characterized in that: the plurality of the recessed portions (21c) are formed in a longitudinal direction of the core base material portion (21); core base material portion exposed parts of each recessed portion (21c) have a long, thin shape in an inclined direction intersecting both the longitudinal direction and a lateral direction orthogonal thereto; and a maximum dimension of the recessed portions (21c) in a position in which the dimension in the lateral direction is maximum is at most equal to 0.25 mm.
The present invention provides a composition for oral cavity, which has excellent long-term stability even through a hydrocarbon oil is contained therein. The present invention specifically provides a composition for oral cavity, which contains a hydrocarbon oil, a polyhydric alcohol and a surfactant, and which is configured such that (i) glycerol and a polyglycerol fatty acid ester and/or an alkyl glucoside are contained therein, (ii) propanediol and a polyoxyethylene-hardened castor oil and/or a polyoxyethylene-hardened castor oil fatty acid ester are contained therein, (iii) butylene glycol and a polyoxyethylene alkyl ether and/or a polyoxyethylene-hardened castor oil fatty acid ester are contained therein, or (iv) a polyethylene glycol and a polyoxyethylene-hardened castor oil fatty acid ester are contained therein.
A brush head is provided on the front surface at a distal-end-side part of a neck of a replaceable brush. A fitting shaft portion is provided on a planting base of the brush head so as to protrude rearward and penetrate through a support wall portion of the neck. A shaft hole is formed at a rotation center of a brush head body of the brush head so as to extend frontward from a rear surface of the brush head body. The neck has ahead support shaft mounted to the shaft hole so as to rotatably support the brush head. A front end of the head support shaft is located frontward of a rear surface of the planting base, and power from the driving portion is transmitted to a rear part of the fitting shaft portion.
A61C 17/34 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues ayant un mouvement alternatif ou oscillant entraînées par un moteur électrique
A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues
03 - Produits cosmétiques et préparations de toilette; préparations pour blanchir, nettoyer, polir et abraser.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
21 - Ustensiles, récipients, matériaux pour le ménage; verre; porcelaine; faience
Produits et services
Dentifrices; liquid toothpaste; mouthwash; breath freshening
sprays; soaps and detergents; shampoos; toilet water;
cosmetics; cosmetic preparations for skin care; hair care
preparations; toiletry preparations; incense. Medicines for dental purposes; candies for medical purposes;
pharmaceutical preparations and other preparations for
destroying vermin, fungicides, herbicides; medicated
dentifrices; medicated mouth rinse; plaque disclosing
agents; gauze for dressings; dental materials; dental
cements; dental wax; dental filling materials; dietary
supplements for humans; nutritional supplements; plant
extract dietary supplements in the form of pill, capsule,
powder, liquid, jelly, and in granular form; lactic acid
bacteria dietary supplements in the form of pill, capsule,
powder, liquid, jelly, and in granular form. Toothbrushes; interdental cleaners; cosmetic and toilet
utensils; electric toothbrushes; floss for dental purposes;
dental picks for interdental cleaning.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Medicinal alcoholic beverages; pharmaceuticals as intestinal
regulators; antiflatulants; mouthwashes for medical
purposes; medicated toiletry preparations; dietary
supplements for humans; nutritional supplements; dietetic
beverages adapted for medical purposes; dietetic foods
adapted for medical purposes; dental materials; cotton swabs
for medical use; pharmaceutical preparations; medicinal hair
growth preparations.
31.
Tripeptides having angiotensin converting enzyme inhibitory activity and uses thereof
Provided is a material with which it is possible to prepare a composition for external use that brings about a highly smooth feeling with low roughness while reflecting near-infrared rays. Specifically, provided is a granular composite comprising keratin and hexagonal plate-like zinc oxide particles.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations and substances, and medicated hygiene preparations for oral and dental treatment, namely, those for the treatment of periodontal diseases and disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations; pharmaceutical preparations for dental purposes; ointment for treatment of periodontal disease; local antibiotics for dental purposes; topical ointment/gel containing antibiotics; dental wax; dental cements; diagnostic preparations for periodontal disease; diagnostic preparations for dental caries; dentifrices for medical purposes; mouthwashes for medical purposes; disclosing agents for bacterial plaque.
[Problem] To provide an electric toothbrush (10) in which the operability of a replaceable toothbrush (30) head part (34) inside the mouth can be improved by configuring the head part (34) in a small size in the front-back direction, and furthermore, the stability of operation of a brush head (40) can be improved and power consumption can be reduced by reducing the friction resistance of the brush head (40) and a handle body (32) and the vibration of the brush head (40). [Solution] The brush head (40) is provided on the front surface side of the tip side portion of a handle body (31) of the replaceable toothbrush (30). A fitting shaft part (45) protruding rearward and passing through a support wall part (37) of the handle body (31) is provided on a bristle planting base (42) of the brush head (40). A shaft hole (41a) extending forward from the rear surface of a brush head body (41) is formed in a rotation center of the brush head body (41) of the brush head (40). A head support shaft (49) attached to the shaft hole (41a) and rotatably supporting the brush head (40) is provided on the handle body (31). In addition, the front end section of the head support shaft (49) is disposed further forward than the rear surface of the bristle planting base (42) to transmit power from a drive part (13) to the rear section of the fitting shaft part (45).
A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues
A61C 17/34 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues ayant un mouvement alternatif ou oscillant entraînées par un moteur électrique
Provided is an oil-in-water emulsion composition which contains meadowfoam oil having uniform oil particles with a small average particle size and a narrow particle size distribution. Specifically, provided is an oil-in-water emulsion composition containing the following components: (A) meadowfoam oil; (B) N-acylglutamic acid and/or a salt thereof; (C) a water-soluble sucrose fatty acid ester; and (D) a glycerin mono-fatty acid ester.
A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés
Provided is a composition containing linoleic acid and/or a derivative thereof which has enhanced stability over time. More specifically, the composition comprises a continuous phase and multilayered liposomes dispersed in the continuous phase, wherein the continuous phase contains at least one compound selected from the group consisting of carboxyvinyl polymers, salts thereof, and cellulosic polymers and the multilayered liposomes contain a cationized polymer in the layers and have, enclosed therein, linoleic acid and/or a derivative thereof.
A61K 8/81 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons insaturées carbone-carbone
A61Q 19/00 - Préparations pour les soins de la peau
Provided are a toothbrush module, a toothbrush attachment, a brushing assistance system, a brushing evaluation system, a brushing assistance device, and a brushing assistance program that ease obtainment of a brushing action of a user even during brushing.
A toothbrush attachment (2) includes: a sensor unit (21) that detects a predetermined physical quantity; a wireless transmission unit (22) that transmits a radio signal indicating the physical quantity detected by the sensor unit (21); a housing unit (201) that houses the sensor unit (21) and the wireless transmission unit (22); and a coupling mechanism (202) that removably attaches the housing unit (201) to a toothbrush (4). A wireless terminal device (3) includes a wireless receiver (31) that receives a radio signal and obtains the physical quantity, a music output unit (354) that outputs an image or sound so as to support brushing by a user with the toothbrush (4) based on the physical quantity, a figure display control unit (363), and a notification unit (373).
The present invention relates to an allergen activity-reducing agent composition which can reduce the activity of an allergen such as mites and pollens. The allergen activity-reducing agent composition comprises 0.04 to 0.2% by weight of an aromatic hydroxy compound and 0.005 to 0.02% by weight of tannin and is adjusted to pH 2 to 6. The allergen activity-reducing agent composition can reduce an allergen effectively without coloring the surface of a houseware having the allergen adhered thereon to stain the surface of the houseware or without breaking the houseware.
A method to suppress obesity, comprising administering to a subject in need thereof an effective amount of a composition comprising the following components (A) and (B): (A) oleuropein; and (B) a sulforaphane compound, wherein the amount of component (A) alone contained in the composition does not result in a fat accumulation-suppressing effect, and the amount of component (B) alone contained in the composition does not result in a fat accumulation-suppressing effect.
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A23G 4/06 - Chewing-gum caractérisé par la composition
A23G 4/12 - Chewing-gum caractérisé par la composition contenant des micro-organismes ou des enzymesChewing-gum caractérisé par la composition contenant des agents paramédicaux ou diététiques, p. ex. des vitamines
A61K 31/26 - Esters d'acide cyanique ou isocyaniqueEsters d'acide thiocyanique ou isothiocyanique
A61K 47/46 - Ingrédients de constitution indéterminée ou leurs produits de réaction, p. ex. peau, os, lait, fibre de coton, coquille d’œuf, fiel de bœuf ou extraits de plante
A61K 36/31 - Brassicaceae ou Cruciferae (famille de la moutarde), p. ex. broccoli, chou ou chou-rave
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A23L 2/02 - Boissons non alcooliséesCompositions sèches ou concentrés pour les fabriquer Leur préparation ou leur traitement contenant des jus de fruits ou de légumes
An object of the present invention is to provide a composition for improving blood sugar metabolism, the composition improving and/or enhancing sugar metabolism function in skeletal muscle. The present invention provides a composition for improving blood sugar metabolism, the composition comprising a persimmon leaf extract obtained by a process comprising extracting persimmon leaves with a 40-60% ethyl alcohol-water mixture.
A01N 65/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux contenant du matériel provenant d'algues, de lichens, de bryophytes, de champignons multicellulaires ou de plantes, ou leurs extraits
A61K 36/44 - Ebenaceae (famille de l'ébène), p. ex. plaqueminier
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
48.
TOOTHBRUSH MODULE, ATTACHMENT FOR TOOTHBRUSH, TOOTH-BRUSHING ASSISTANCE SYSTEM, TOOTH-BRUSHING EVALUATION SYSTEM, TOOTH-BRUSHING ASSISTANCE DEVICE, AND TOOTH-BRUSHING ASSISTANCE PROGRAM
[Problem] To provide a toothbrush module, an attachment for a toothbrush, a tooth-brushing assistance system, a tooth-brushing evaluation system, a tooth-brushing assistance device, and a tooth-brushing assistance program with which it is easy to know information relating to the tooth-brushing behavior of a user even during tooth brushing. [Solution] An attachment (2) for a toothbrush is provided with: a sensor unit (21) for detecting prescribed physical quantities; a wireless transmission unit (22) for transmitting a wireless signal indicating the physical quantities detected by the sensor unit (21); a housing (201) for accommodating the sensor unit (21) and the wireless transmission unit (22); and a connection mechanism (202) for removably attaching the housing (201) to the toothbrush (4). A wireless terminal device (3) is provided with: a wireless reception unit (31) for receiving the wireless signal and acquiring the physical quantities; a music output unit (354) for outputting an image or a sound so as to assist the tooth polishing of the user with the toothbrush (4) on the basis of the physical quantities; a character display control unit (363); and a notification unit (373).
An interdental cleaning tool (1) that is inserted between teeth, is for cleaning between teeth, and comprises: a rod-shaped core section (12); and a soft section (20) that is softer than the core section (12) and is coated on at least some of the outer surface of the core section (12) including a core tip section (P1) being the tip of the core section (12). The length of the soft section (20) is at least 0.5 mm from the core tip section (P1) to a soft tip section (P2) being the tip of the soft section (20).
The purpose of the present invention is to further enhance the useful effects of bifidobacteria. Provided is an oral composition containing (A) Bifidobacterium breve MCC1274 (FERM BP-11175) and (B) at least one cruciferous vegetable selected from the group consisting of broccoli and cabbage.
The present invention addresses the problem of providing a hair quality improving composition whereby body and control can be imparted to hair, a sense of volume during styling can easily be produced, and excellent feel and softness can be imparted to hair. The present invention contains one or more types of zinc compounds selected from the group consisting of zinc acetate, zinc gluconate, zinc chloride, zinc lactate, and zinc pyrrolidonecarboxylate, and provides a negatively charged hair composition.
An electric toothbrush with a thinner handle part to ensure the ease of manual tooth-brushing while improving the ease of a switch operation between the operating state and the stopped state, the electric toothbrush being configured to realize an effective oral cleaning by automatically giving a necessary mechanical assistance to a brush part according to the brushing state constantly varying during tooth-brushing depending on the cleaned part and the ways of holding and moving the toothbrush.
A46B 15/00 - Autres brossesBrosses avec aménagements additionnels
A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues
A61C 17/34 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues ayant un mouvement alternatif ou oscillant entraînées par un moteur électrique
Provided is a linear actuator which is simple in structure, inexpensive to manufacture, in addition, has small magnetic leakage, and can provide a large inertial force without increasing the number of parts and weight. The linear actuator is provided with an output shaft 12 which is supported on a supporting case 11 so as to linearly reciprocate freely, an elastic member 13 which biases the output shaft 12 toward a middle position of the linear reciprocation thereof, a permanent magnet 14 which is fixed to the output shaft 12, a coil 15 which linearly reciprocates the output shaft 12 by having a variable magnetic field act on the permanent magnet 14 and is fixed to the supporting case 11 such that the coil 15 faces one of magnetic poles of the permanent magnet 14, a yoke 16, which is composed of a magnetic material, has a midway portion tightly secured to the other magnetic pole of the permanent magnet 14, extends to the exterior of the coil 15 along the exterior of the permanent magnet 14 with a space from the permanent magnet 14, and has an end portion disposed close to the exterior of the coil 15, and power supply means for forming a variable magnetic field on the coil 15.
H02K 33/16 - Moteurs avec un aimant, un induit ou un système de bobines à mouvement alternatif, oscillant ou vibrant avec des induits polarisés se déplaçant dans des directions opposées par inversion de la tension appliquée au système à une seule bobine
H02K 33/12 - Moteurs avec un aimant, un induit ou un système de bobines à mouvement alternatif, oscillant ou vibrant avec des induits se déplaçant dans des directions opposées par alimentation alternée de systèmes à deux bobines
A61C 17/34 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues ayant un mouvement alternatif ou oscillant entraînées par un moteur électrique
H02K 33/02 - Moteurs avec un aimant, un induit ou un système de bobines à mouvement alternatif, oscillant ou vibrant avec des induits entraînés dans un sens par application d'énergie à un système à une seule bobine et ramenés par une force d'origine mécanique, p. ex. par des ressorts
H02K 16/00 - Machines avec plus d'un rotor ou d'un stator
Provided is an electrically driven toothbrush which has a handle formed thin and slim to improve the operability and design and which is configured in such a manner that an induction coil is assembled in an inner member which protrudes to the outside from an outer case, thereby enabling the electrically driven toothbrush to be charged without contact. A handle (2) serving as a grip is provided with: a metallic cylindrical outer case (4) having a first end (4a) and a second end (4b); an inner member (5) having a small end (5a) which is inserted through the first end (4a) and also having a large end (5b) which is engaged with the second end (4b), the inner member (5) being installed within the outer case (4) by being inserted with the small end (5a) first into the outer case (4) from the second end (4b) side thereof; a restriction member (7) fitted over and affixed to the small end (5a), which protrudes to the outside from the first end (4a), by means of a joining structure (6), the restriction member (7) engaging with the first end (4a) of the outer case (4) and preventing, in cooperation with the large end (5b), the outer case (4) from separating from the inner member (5); and a vibration generation means (9) assembled in the inner member (5) in order to vibrate a replaceable brush (3).
A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues
A61C 17/34 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues ayant un mouvement alternatif ou oscillant entraînées par un moteur électrique
[Problem] To provide an electric toothbrush capable of enhancing cleaning properties between teeth while adequately maintaining cleaning properties on a tooth surface or tooth neck. [Solution] An electric toothbrush (1) having a brush part (2) in which bristle bundles (14) are implanted in implantation holes (13) of an implantation base (12), a handle part (3) as a grip for operating the brush part (12), and a vibration generating means (5) housed in the handle part (3), the vibration generating means (5) for rotating an eccentric weight (32) about an axis aligned with a length direction of the handle part (3) and causing the brush part (2) to vibrate, wherein level-difference bristle bundles (14A) implanted in the implantation holes (13) so that a level difference (H) is formed in a distal-end part thereof are provided as the bristle bundles (14).
A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues
A61C 17/34 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues ayant un mouvement alternatif ou oscillant entraînées par un moteur électrique
The objective of the present invention is to provide an anti-obesity composition which suppresses fat accumulation into adipocytes and has a body weight gain suppressing action. The present invention provides an anti-obesity composition which comprises (A) and (B): (A) At least one type selected from the group consisting of oleuropein and hydroxytyrosol. (B) At least one type selected from the group consisting of a sulforaphane compound and Salix extract.
A61K 31/145 - Amines, p. ex. amantadine ayant des atomes de soufre, p. ex. thiurames (N-C(S)-S-C(S)-N ou N-C(S)-S-S-C(S)-N)Sulfinylamines (-N=SO)Sulfonylamines (-N=SO2)
In the present invention, the following are provided: an air pump (14); a motor (15) and a battery (16); a mist nozzle (12); a tank (13); and a vertically long cylindrical main case (1) that accommodates the foregoing devices. A mist opening (3) is provided to the upper part of a front wall (1a) of the main case (1), and the mist nozzle (12) is provided within the mist opening (3). The interior of the main case (1) is divided into a front chamber (1A) and a rear chamber (1B) by a dividing wall (23), and the front chamber (1A) accommodates the tank (13). The rear chamber (1B) has provided therein an electrical component unit (17) that includes, in the order given, the air pump (14), the motor (15), and the battery (16). The tank (13) is formed vertically long and occupies most of the front chamber (1A), and the capacity of the tank (13) is increased without affecting the external shape of the main case (1). On the upper part of the rear surface of the main case (1), a grip section (5) is formed so as to be recessed, and the air pump (14) and the motor (15) are provided near the grip section (5).
B05B 7/30 - Appareillages dans lesquels des liquides ou d'autres matériaux fluides en provenance de différentes sources sont mélangés avant de pénétrer dans le dispositif d'évacuation dans lesquels un liquide ou autre matériau fluide est introduit ou attiré, en passant par un orifice, dans un courant de fluide porteur le premier liquide ou autre matériau fluide étant introduit par gravité ou aspiré dans le fluide porteur
A45D 34/04 - Récipients ou accessoires spécialement conçus pour l'emploi de produits de toilette ou cosmétiques liquides, p. ex. de parfums spécialement conçus pour étendre un liquide, p. ex. à l'aide d'un rouleau ou d'une bille
A61M 11/02 - Pulvérisateurs ou vaporisateurs spécialement destinés à des usages médicaux agissant par pression d'air sur les liquides à pulvériser ou vaporiser
The purpose of the present invention is to provide a composition for improving blood sugar metabolism whereby the sugar metabolism function in the skeletal muscles is improved and/or enhanced. Provided is a composition for improving blood sugar metabolism, said composition comprising a persimmon leaf extract that is obtained by extracting persimmon leaves with a liquid mixture of 40-60% of ethyl alcohol and water.
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
An object of the present invention is to provide an electric toothbrush with a thinner handle part to ensure the ease of manual tooth-brushing while improving the ease of a switch operation between the operating state and the stopped state, the electric toothbrush being configured to realize an effective oral cleaning by automatically giving a necessary mechanical assistance to a brush part according to the brushing state constantly varying during tooth-brushing depending on the cleaned part and the ways of holding and moving the toothbrush.The electric toothbrush includes: a toothbrush main body (2) having a brush part (15) and a handle part (20) for manually operating the brush part (15); a vibration generation means (3) that vibrates the brush part (15); an acceleration sensor (4) that detects a manual brushing action; and a control means (5) that controls at least the vibration generation means (3).
A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues
A61C 17/26 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues tournant en continu entraînées par un moteur électrique
[Problem] To provide an electric toothbrush that: is capable of ensuring the ease of a manual brushing operation by making a handle part thinner, while improving the ease of a switching operation between an operating state and a stopped state; and achieves efficient oral cavity cleaning by automatically providing necessary and sufficient mechanical assistance to a brush part in response to brushing conditions that constantly change during brushing, such as cleaning location, and the way of holding and moving the toothbrush. [Solution] An electric toothbrush is provided with: a brush part (15); a toothbrush body (2) having a handle part (20) for manually operating the brush part (15); a vibration-generating means (3) that causes the brush part (15) to vibrate; an acceleration sensor (4) that senses a manual brushing operation; and a control means (5) that switches at least the vibration-generating means (3) between an operating state and a stopped state on the basis of output from the acceleration sensor (4).
A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues
A61C 17/26 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues tournant en continu entraînées par un moteur électrique
62.
Cosmetic tool, retainer of cosmetic material and method of manufacturing cosmetic tool
This application aims at providing a retainer of a cosmetic material and a method of manufacturing a cosmetic tool, which are capable of easily treating the cosmetic material even when decreasing a concentration of skin care ingredients of the cosmetic material produced by freeze-drying. A cosmetic tool (1) includes: a retainer (3) to include an annular frame (2) and a handle (5) for holding the frame (2); and a cosmetic material (4) to be produced by freeze-drying an aqueous solution of skin care ingredients and fixed in a way that covers an aperture of the frame (2).
A45D 33/24 - Récipients à double couvercle du même côtéRécipients à couvercles multiples
A45D 33/00 - Récipients ou accessoires spécialement conçus pour l'emploi de produits de toilette ou cosmétiques en poudre
A45D 40/00 - Emboîtages ou accessoires spécialement conçus pour la conservation ou l'emploi de produits de toilette ou cosmétiques solides ou pâteux, p. ex. de savons à barbe ou de rouges à lèvres
A61K 8/65 - CollagèneGélatineKératineLeurs dérivés ou produits de dégradation
A61Q 19/00 - Préparations pour les soins de la peau
A61K 8/02 - Cosmétiques ou préparations similaires pour la toilette caractérisés par une forme physique particulière
An oral composition includes high stain removal efficiency relative to its abrasive ability. The oral composition contains fused silica and a dental abrasive. The oral composition has a high stain removal ability relative to the abrasive ability thereof. In other words, the ratio (stain removal ability/abrasive ability) of the oral composition is high. Accordingly, the use of the oral composition makes it possible to efficiently remove stains without damaging the teeth more than necessary.
[Problem] To provide an oral cleaning device which employs a small and low-cost electric air pump with a low output and which is capable of securing enough delivery pressure for a cleaning liquid. [Solution] An oral cleaning device comprises: a cleaning liquid tank (2) which stores a cleaning liquid and can be closed in an air-tight manner; a cleaning liquid supply passage (24) which is provided with a delivery port (4a) for delivering the cleaning liquid into the mouth on one end and an introduction port (23a) which opens to the bottom of the cleaning liquid tank (2) on the other end; and an electric air pump (44) which supplies air to the inside of the cleaning liquid tank (2) and pressurizes the inside of the cleaning liquid tank (2). This device supplies the cleaning liquid inside the cleaning liquid tank (2) to the delivery port (4a) through the cleaning liquid supply passage (24) by air pressure inside the cleaning liquid tank (2). An air introduction hole (71) that opens on a middle part of the cleaning liquid supply passage (24) is provided, and a portion of the air that is supplied from the air pump (44) to the cleaning liquid tank (2) is supplied to the cleaning liquid supply passage (24) through the air introduction hole (71) and the cleaning liquid is delivered in a pulsatile manner from the delivery port (4a).
[Problem] To provide an oral cleaning device which employs a small and low-cost electric air pump with a low output and which is capable of securing enough delivery pressure for a cleaning liquid. [Solution] An oral cleaning device comprises: a cleaning liquid tank (2) which stores a cleaning liquid and can be closed in an air-tight manner; a cleaning liquid supply passage (24) which is provided with a delivery port (4a) for delivering the cleaning liquid into the mouth on one end and an introduction port (23a) which opens to the bottom of the cleaning liquid tank (2) on the other end; and an electric air pump (44) which supplies air to the inside of the cleaning liquid tank (2) and pressurizes the inside of the cleaning liquid tank (2). This device supplies the cleaning liquid inside the cleaning liquid tank (2) to the delivery port (4a) through the cleaning liquid supply passage (24) by air pressure inside the cleaning liquid tank (2). An air introduction hole (71) that opens on a middle part of the cleaning liquid supply passage (24) is provided, and a portion of the air that is supplied from the air pump (44) to the cleaning liquid tank (2) is supplied to the cleaning liquid supply passage (24) through the air introduction hole (71) and the cleaning liquid is delivered in a pulsatile manner from the delivery port (4a).
[Problem] To provide an interdental cleaning tool which exhibits excellent interdental insertability, and is capable of sufficiently ensuring cleaning properties when saliva is present. [Solution] An interdental cleaning tool (1) equipped with a handle substrate (11) comprising a synthetic resin, and a cleaning part (2) obtained by sheathing the long and thin shaft-shaped core (12) of the handle substrate (11) in a cleaning-part body (21) comprising an elastomer, the cleaning-part body (21) having a covering section (21a) for covering the core (12) and a plurality of cleaning projections (21b) for projecting outward from the covering section (21a). Furthermore, the cleaning-part body (21) is made from a styrene-based thermoplastic elastomer having a shore (A) hardness of A25-A55, and given that the coefficient of dynamic friction when water is not interposed in the cleaning part (2A) is μd, and the coefficient of dynamic friction when water is interposed therein is μw, then the relational expression 0.9×μd≤μw between both coefficients of dynamic friction is satisfied.
The present invention was made in view of an object to produce a novel proteoglycan-containing material, and find a novel use and/or a superior effect of the proteoglycan-containing material. The present invention provides a proteoglycan-containing material obtained from fish cartilage, wherein the proteoglycan-containing material comprises an acidic saccharide component having a molecular weight of not less than 2000 kDa. The proteoglycan-containing material provides advantageous effects for skin-moisturizing and skin anti-aging, including a superior skin fibroblast proliferation effect, an effect of enhancing and improving the skin barrier function, an effect of enhancing and improving the skin's capability to produce collagen, a dermis-thickening inhibition effect, and the like.
The present invention addresses the problem of providing a means for preventing or treating osteoarthrosis. The present invention provides a composition for preventing or treating osteoarthrosis, which contains an extract of a fish cartilage with water, wherein the extract contains a proteoglycan having a molecular weight of 1,800,000 or more.
An object of the present invention is to provide a bone regeneration material suitable for bone (in particular, alveolar bone) regeneration. The present invention provides a non-woven fabric containing a bone prosthetic material wherein the bone prosthetic material is included between biocompatible fibers that constitute the non-woven fabric. The non-woven fabric may be suitably used as a bone regeneration material (in particular, a dental bone regeneration material).
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61L 27/46 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges inorganiques contenant du phosphore
An object of the present invention is to provide a tryptanthrin-containing indigo-plant leaf extract particularly suitable for application to the skin. The present invention provides a method for producing a tryptanthrin-containing indigo-plant leaf extract, the method comprising filtering a mixture of a concentrated ethanol extract of indigo-plant leaves and a polyhydric alcohol, and collecting the filtrate. The present invention further provides an indigo-plant leaf extract produced by this method.
A61K 36/704 - Polygonum, p. ex. renouée des oiseaux
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61Q 17/00 - Préparations protectricesPréparations employées en contact direct avec la peau pour protéger des influences extérieures, p. ex. des rayons du soleil, des rayons X ou d'autres rayons nuisibles, des matériaux corrosifs, des bactéries ou des piqûres d'insectes
A61Q 19/00 - Préparations pour les soins de la peau
A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
71.
Test kit for plasma or serum antibody titer against periodontal disease-causing bacteria
The object of the present invention is to provide: a test kit for an antibody titer or an antibody against a periodontal disease-causing bacterium in a blood sample, which enables the testing on a periodontal disease in patients having a wide scope of immunotypes with high accuracy and can be treated by an automated device at a high speed; a periodontal disease-causing bacterium antigen protein which can be suitably used in the kit; a method for testing an antibody titer or the presence of an antibody in a blood sample using the kit; and a kit for typing strains of Porphyromonas gingivalis. The present invention discloses: a test kit comprising a set of polypeptides respectively having the acid sequences represented by SEQ ID NOs: 1, 3, 9, 15, 19, 31, 41, 43, 63, 65 and 67; a modified polypeptide having the amino acid sequence represented by SEQ ID NO: 67; and a method for determining an antibody titer or the presence of an antibody against a periodontal disease-causing bacterium in a blood sample separated from a human body, comprising bringing the blood sample into contact with the above-mentioned set of polypeptides.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
C07K 14/195 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
An object of the present invention is to provide a composition for external use comprising a polyunsaturated fatty acid having higher stability over time. The present invention provides the following composition, in which the stability over time of a polyunsaturated fatty acid is high.
(B) liposomes containing a polyunsaturated fatty acid or a derivative thereof.
A61K 8/02 - Cosmétiques ou préparations similaires pour la toilette caractérisés par une forme physique particulière
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/201 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p. ex. acides stéarique, palmitique ou arachidique ayant une ou deux doubles liaisons, p. ex. acides oléique ou linoléique
A61K 8/36 - Acides carboxyliquesLeurs sels ou anhydrides
A61K 8/55 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant du phosphore
NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (Japon)
Inventeur(s)
Ishii, Miwa
Oka, Toru
Nakayama, Yoshimitsu
Torii, Masumi
Sugimori, Masaru
Takashiba, Shogo
Maeda, Hiroshi
Mineshiba, Fumi
Hirai, Kimito
Abrégé
[Problem] To provide: a bactericidal agent composition which can exhibit an excellent bactericidal effect in the presence of an organic substance and against biofilms; a method for producing the bactericidal agent composition; and a sterilization method using the bactericidal agent composition. [Solution] A bactericidal agent composition which comprises water containing nanobubbles having a most frequent particle diameter of 500 nm or less and a bactericidal component. Preferably, the density of most frequent particles of the nanobubbles is 10,000 particles or more and the density of nanobubbles each having a particle diameter of 1000 nm or less is 1,000,000 particles or more.
A01N 25/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles
A01N 25/02 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des liquides comme supports, diluants ou solvants
A01N 29/02 - Composés acycliques ou composés contenant un halogène lié à une chaîne latérale aliphatique d'un système cycloaliphatique
A01N 59/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des éléments ou des composés inorganiques
A01N 65/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux contenant du matériel provenant d'algues, de lichens, de bryophytes, de champignons multicellulaires ou de plantes, ou leurs extraits
A01N 65/36 - Rutaceae [famille de la rue], p. ex. citron vert, orange, citron, chêne-liège ou clavelier
A61L 2/18 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances liquides
[Problem] To provide an interdental brush configured so that the brush section can be satisfactorily inserted between grinding teeth, the breakage of the base of a core material which is exposed from a neck section is effectively prevented, the interdental brush can be stably operated during interdental cleaning, pain caused by the contact between the front end of the handle section and the gums can be prevented, and the interdental brush can be manufactured at low cost. [Solution] An interdental brush (1) has a brush section (3) formed by planting filaments in a core material (2) constructed from a wire, and also has a handle section (10) as the hand grip. The base of the core material (2) is held at the front end of the handle section (10), and the brush section (3) is supported by the handle section (10). The handle section (10) is provided with a handle body (11) and a neck section (12) which is provided at the front end of the handle body (11). A neck base material (22) which is flat, consists of a synthetic resin, and can be bent is provided to the neck section (12). The base of the core material (2) is embedded in the neck base material (22).
To provide an economical and sanitary drug-containing personal hygiene implement that is easy to produce and manage, and has an excellent portability even when both personal hygiene implement and drug are used away from home.
The drug-containing personal hygiene implement includes a bottle body in which a drug is stored, a personal hygiene body which has a shaft section and a distal-end personal hygiene section, protrudes to a distal-end side of the bottle body, and is used to implement care of a human body, and a passage provided on a distal-end section of the bottle body and guiding the stored drug to the personal hygiene body, the implement being characterized in that opening operation makes it possible for the drug to flow through the passage in the bottle body.
A61C 17/00 - Dispositifs pour nettoyer, polir, rincer ou sécher les dents, les cavités dentaires ou les prothèsesAppareils pour enlever la saliveRéceptacles pour les crachats à usage dentaire
A61C 15/00 - Dispositifs de nettoyage de l'intervalle des dents
A61B 17/24 - Instruments, dispositifs ou procédés chirurgicaux pour la cavité buccale, le larynx, les conduits des bronches ou le nezGrattoirs pour la langue
A46B 9/04 - Position ou disposition des soies par rapport à la surface de la monture, p. ex. inclinées, en rangées, en groupes pour les brosses à dents
A46B 11/00 - Brosses à réservoir ou autre système permettant l'application de produits, p. ex. peintures, pâtes, eau
A46B 15/00 - Autres brossesBrosses avec aménagements additionnels
A46B 17/04 - Couvertures protectrices pour les soies
76.
Retinol-modified collagen, method for producing same, and external composition for skin containing same
NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (Japon)
SUNSTAR INC. (Japon)
Inventeur(s)
Tanihara, Masao
Takaichi, Kana
Maeda, Mariko
Mitsui, Tsukasa
Yamamoto, Kazushi
Hirano, Akiko
Abrégé
Disclosed is a compound which exhibits a higher effect of preventing wrinkle formation, a higher effect of improving wrinkles, a higher effect of making the skin beautiful, and a higher effect of improving skin quality than conventional retinol and retinol derivatives in a sustained manner. Further disclosed are a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient. More specifically disclosed are retinol-modified collagen in which a dicarboxylic acid is attached to at least one hydroxyl group of collagen and retinol is attached to a carboxyl group of at least one attached dicarboxylic acid, a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.
An objective of the present invention is to provide a cosmetics implement, a cosmetics retention tool, and a cosmetics implement manufacturing method with which it is possible to easily handle cosmetics even if the concentration of skin care components of the cosmetics which are formed by freeze-drying is reduced. A cosmetics implement (1) comprises: a retention tool (3), further comprising a ring-shaped frame (2) and a handle (5) for holding the frame (2); and a cosmetic (4) which is formed by freeze-drying a water solution of a skin care component, and is fixed to seal the opening of the frame (2).
A45D 40/00 - Emboîtages ou accessoires spécialement conçus pour la conservation ou l'emploi de produits de toilette ou cosmétiques solides ou pâteux, p. ex. de savons à barbe ou de rouges à lèvres
A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
A61K 8/65 - CollagèneGélatineKératineLeurs dérivés ou produits de dégradation
Provided is a core/sheath composite filament for toothbrushes which exhibits excellent hardness, durability and feeling of use when used in toothbrushes, is less prone to falling out when tufted into the tufting plate, and makes it possible to improve stain-removal properties. Also provided is a toothbrush using said core/sheath composite filament. A toothbrush is configured using bundles of bristles configured from core/sheath composite filaments that have a quadrangular cross section in the plane perpendicular to the lengthwise direction and comprise a core (2), which is formed from a synthetic resin fiber, and a sheath (3), which integrally covers the core (2) and is formed from an elastomer that is compatible with the synthetic resin constituting the core (2). Tufts configured from a plurality of the core/sheath composite filaments (1) are tufted in the center portion of a tufting plate.
A46B 9/04 - Position ou disposition des soies par rapport à la surface de la monture, p. ex. inclinées, en rangées, en groupes pour les brosses à dents
An oral composition includes high stain removal efficiency relative to its abrasive ability. The oral composition contains fused silica and a dental abrasive. The oral composition has a high stain removal ability relative to the abrasive ability thereof. In other words, the ratio (stain removal ability/abrasive ability) of the oral composition is high. Accordingly, the use of the oral composition makes it possible to efficiently remove stains without damaging the teeth more than necessary.
The present invention addresses the problem of providing a tryptanthrin-containing Polygonum tinctorium extract particularly suitable for dermal applications. The present invention provides a method for producing a tryptanthrin-containing Polygonum tinctorium extract, the method comprising a step for filtering a mixture comprising an ethanol-extracted concentrate of Polygonum tinctorium and a polyhydric alcohol, and recovering the filtrate. Also provided is the Polygonum tinctorium extract produced by this production method.
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés
A61K 31/502 - PyridazinesPyridazines hydrogénées condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. cinnoline, phtalazine
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
The purpose of the present invention is to provide a bone regeneration material suitable for the regeneration of bones (particularly alveolar bones). The present invention provides a non-woven fabric containing a bone prosthetic material, wherein the bone prosthetic material is contained between fibers that constitute the non-woven fabric, and the fibers that constitute the non-woven fabric are biocompatible fibers. The non-woven fabric can be used suitably as a bone regeneration material (particularly a bone regeneration material for dental applications).
The purpose of the present invention is to provide a bone regeneration material suitable for the regeneration of bones (particularly alveolar bones). The present invention provides a non-woven fabric containing a bone prosthetic material, wherein the bone prosthetic material is contained between fibers that constitute the non-woven fabric, and the fibers that constitute the non-woven fabric are biocompatible fibers. The non-woven fabric can be used suitably as a bone regeneration material (particularly a bone regeneration material for dental applications).
The purpose of the present invention is to provide a composition for external applications, in which the long-term stability of a polyunsaturated fatty acid is further increased. The present invention provides a composition as mentioned below. In the composition, the long-term stability of a polyunsaturated fatty acid is improved. A composition comprising components (A) and (B) as mentioned below, wherein the component (B) is dispersed in a continuous phase containing the component (A): (A) at least one component selected from the group consisting of tocopherol and phytic acid; and (B) a liposome containing a polyunsaturated fatty acid or a derivative thereof.
A61K 8/36 - Acides carboxyliquesLeurs sels ou anhydrides
A61K 8/44 - Acides aminocarboxyliques ou leurs dérivés, p. ex. acides aminocarboxyliques contenant du soufreLeurs sels, esters ou dérivés N-acylés
A61K 8/55 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant du phosphore
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 31/201 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p. ex. acides stéarique, palmitique ou arachidique ayant une ou deux doubles liaisons, p. ex. acides oléique ou linoléique
A61K 31/6615 - Composés ayant plusieurs groupes d'acide du phosphore estérifiés, p. ex. triphosphate d'inositol, acide phytique
A61K 47/08 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant de l'oxygène
A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés
A61K 47/24 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant des atomes autres que des atomes de carbone, d'hydrogène, d'oxygène, d'halogènes, d'azote ou de soufre, p. ex. cyclométhicone ou phospholipides
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
The objective of the present invention is to obtain a useful extract from aquatic animal tissues. The present invention provides a fish-cartilage water extract containing proteoglycans having molecular weights greater than or equal to 2,500,000. This extract has excellent anti-aging effects to the skin (particularly, anti-inflammatory effect, the effect of improving the barrier function of the skin, and the effect of improving the moisture retainability of the skin). Moreover, this fish-cartilage water extract achieves the aforementioned effects not only by application to the skin, but also through oral ingestion.
A61K 35/60 - Poissons, p. ex. hippocampesŒufs de poisson
A23L 1/30 - contenant des additifs (A23L 1/308 a priorité);;
A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
A61K 8/98 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés d'origine animale
A61K 38/00 - Préparations médicinales contenant des peptides
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61Q 19/08 - Préparations contre le vieillissement
C07K 14/46 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés
C08B 37/00 - Préparation des polysaccharides non prévus dans les groupes Leurs dérivés
85.
TEST KIT FOR PLASMA OR SERUM ANTIBODY TITER AGAINST PERIODONTAL DISEASE-CAUSING BACTERIA
The purpose of the present invention is to provide: a test kit for an antibody or antibody titer against periodontal disease-causing bacteria in a blood sample, which is capable of examining periodontal diseases of patients having a wide range of immunological types with high accuracy, and which can be processed at a high speed with an automated device; a periodontal disease-causing bacteria antigen protein which is suitable for use in the kit; a method for determining the presence of an antibody or the antibody titer in a blood sample using the kit; and a typing kit for Porphyromonas gingivalis strain. The present invention discloses: a test kit which contains a series of polypeptides that comprise the acid sequences represented by SEQ ID NOS. 1, 3, 9, 15, 19, 31, 41, 43, 63, 65 and 67; a modified polypeptide which comprises the amino acid sequence represented by SEQ ID NO. 67; and a method for determining the presence of an antibody or the antibody titer against periodontal disease-causing bacteria in a blood sample, which comprises a process wherein the blood sample, which is collected from a human individual, is brought into contact with the above-described series of polypeptides.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
C07K 14/195 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries
An oral care instrument, which can maintain a sufficient support strength of a long neck, leaves little residue of a medicant after using, has a low contamination risk from nozzle tip, allows smooth spouting of a medical solution from the beginning, prevents excessive supply of gelatinous or creamy oral-care composition in the case of flowing the composition in a supply channel inside the same, and contributes to the maintenance of the durability of a manufacturing mold. In the aforesaid oral care instrument, which comprises a handle (2), a head (3) and a neck (4), a channel (11) for supplying oral-care composition running within the neck (4) to a nozzle (10) of the head (3) via the handle (2), is formed; and the head (3) is connected in a detachable manner to the neck (4).
[Problem] To provide an economical and sanitary drug-containing personal hygiene implement that is easy to produce and manage, and has an excellent portability even when used as a personal hygiene implement or a drug applicator outside of the home. [Solution] The drug-containing personal hygiene implement comprises a bottle body in which a drug is stored, a personal hygiene member that has a shaft and a distal-end personal hygiene section, protrudes from the distal end of the bottle body and is used to ensure the personal hygiene of the human body, and a passage that is provided to the distal section of the bottle body and guides the stored drug to the personal hygiene member, said implement being characterized in that the implement opening operation makes it possible for the drug to flow through the passage in the bottle body.
A61C 17/00 - Dispositifs pour nettoyer, polir, rincer ou sécher les dents, les cavités dentaires ou les prothèsesAppareils pour enlever la saliveRéceptacles pour les crachats à usage dentaire
A46B 11/02 - Brosses à réservoir ou autre système permettant l'application de produits, p. ex. peintures, pâtes, eau avec écoulement du produit du réservoir par pression
A46B 15/00 - Autres brossesBrosses avec aménagements additionnels
A61B 17/24 - Instruments, dispositifs ou procédés chirurgicaux pour la cavité buccale, le larynx, les conduits des bronches ou le nezGrattoirs pour la langue
A61C 15/00 - Dispositifs de nettoyage de l'intervalle des dents
88.
RETINOL-MODIFIED COLLAGEN, METHOD FOR PRODUCING SAME, AND EXTERNAL COMPOSITION FOR SKIN CONTAINING SAME
NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (Japon)
SUNSTAR INC. (Japon)
Inventeur(s)
Tanihara, Masao
Takaichi, Kana
Maeda, Mariko
Mitsui, Tsukasa
Yamamoto, Kazushi
Hirano, Akiko
Abrégé
Disclosed is a compound which exhibits a higher effect of preventing wrinkle formation, a higher effect of improving wrinkles, a higher effect of making the skin beautiful, and a higher effect of improving skin quality than conventional retinol and retinol derivatives in a sustained manner. Further disclosed are a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient. More specifically disclosed are retinol-modified collagen in which a dicarboxylic acid is attached to at least one hydroxyl group of collagen and retinol is attached to a carboxyl group of at least one attached dicarboxylic acid, a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.
A61K 31/07 - Composés du rétinol, p. ex. vitamine A
A61K 38/00 - Préparations médicinales contenant des peptides
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61Q 19/00 - Préparations pour les soins de la peau
C07C 403/00 - Dérivés du cyclohexane ou d'un cyclohexène, comportant une chaîne latérale avec une partie non saturée d'au moins quatre atomes de carbone en ligne, ladite partie étant directement attachée aux cycles cyclohexane ou cyclohexène, p. ex. vitamine A, bêta-carotène, bêta-ionone
This invention relates to a composition that stably contains hesperidin. The present invention provides a composition containing (A) hesperidin, (B) at least one dihydric alcohol selected from the group consisting of ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, and 3-methyl-1,3-butanediol, and (C) a sugar alcohol. In the composition, the decomposition of hesperidin is suppressed and hesperidin is stably contained.
Provided is a linear actuator which is simple in structure, inexpensive to manufacture, in addition, has small magnetic leakage, and can provide a large inertial force without increasing the number of parts and weight.
The linear actuator is provided with an output shaft 12 which is supported on a supporting case 11 so as to linearly reciprocate freely, an elastic member 13 which biases the output shaft 12 toward a middle position of the linear reciprocation thereof, a permanent magnet 14 which is fixed to the output shaft 12, a coil 15 which linearly reciprocates the output shaft 12 by having a variable magnetic field act on the permanent magnet 14 and is fixed to the supporting case 11 such that the coil 15 faces one of magnetic poles of the permanent magnet 14, a yoke 16, which is composed of a magnetic material, has a midway portion tightly secured to the other magnetic pole of the permanent magnet 14, extends to the exterior of the coil 15 along the exterior of the permanent magnet 14 with a space from the permanent magnet 14, and has an end portion disposed close to the exterior of the coil 15, and power supply means for forming a variable magnetic field on the coil 15.
H02K 33/00 - Moteurs avec un aimant, un induit ou un système de bobines à mouvement alternatif, oscillant ou vibrant
A61C 17/34 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues ayant un mouvement alternatif ou oscillant entraînées par un moteur électrique
H02K 33/02 - Moteurs avec un aimant, un induit ou un système de bobines à mouvement alternatif, oscillant ou vibrant avec des induits entraînés dans un sens par application d'énergie à un système à une seule bobine et ramenés par une force d'origine mécanique, p. ex. par des ressorts
H02K 16/00 - Machines avec plus d'un rotor ou d'un stator
Provided is an interdental brush having a wire and filaments arranged therein by folding the wire and disposing the filaments between the wire and then twisting the wire. The interdental brush has improved filament retention and improved cleaning effectivity and reachability to minute portions. Each of filaments 3 has a polygonal cross section whose at least one corner portion has an interior angle 31 as acute as 30 to 75 degrees. Specifically, an angle θ3 of the acute corner portion 31 is set at 1.2 to 3 times a twisting angle θ4 of the wire. The filaments each have two or more such acute corner portions, and two or more rows of such filaments are disposed and laminated between the wire in a densely arranged manner.
A46B 9/04 - Position ou disposition des soies par rapport à la surface de la monture, p. ex. inclinées, en rangées, en groupes pour les brosses à dents
A46B 3/18 - Brosses caractérisées par la façon dont les soies sont fixées ou assemblées dans ou sur le corps ou la monture de la brosse les soies étant fixées sur ou entre des courroies ou des fils métalliques
A46D 1/00 - SoiesEmploi de matériaux spécifiés pour les soies
Provided is a core/sheath composite filament for toothbrushes which exhibits excellent hardness, durability and feeling of use when used in toothbrushes, is less prone to falling out when tufted into the tufting plate, and makes it possible to improve stain-removal properties. Also provided is a toothbrush using said core/sheath composite filament. A toothbrush is configured using bundles of bristles configured from core/sheath composite filaments that have a quadrangular cross section in the plane perpendicular to the lengthwise direction and comprise a core (2), which is formed from a synthetic resin fiber, and a sheath (3), which integrally covers the core (2) and is formed from an elastomer that is compatible with the synthetic resin constituting the core (2). Tufts configured from a plurality of the core/sheath composite filaments (1) are tufted in the center portion of a tufting plate.
Provided is a core/sheath composite filament for toothbrushes which exhibits excellent hardness, durability and ease-of-use when used in toothbrushes, is less prone to falling out when implanted into the bristle base, and makes it possible to improve stain-removal properties. Also provided is a toothbrush using said core/sheath composite filament. A toothbrush is configured using bundles of bristles configured from core/sheath composite filaments that have a square cross section in the plane perpendicular to the lengthwise direction and comprise a core (2), which is formed from a synthetic resin fiber, and a sheath (3), which integrally covers the core (2) and is formed from an elastomer that is compatible with the synthetic resin constituting the core (2). Bristle bundles configured from a plurality of the core/sheath composite filaments (1) are implanted in the center portion of a bristle base, and bristle bundles configured from a plurality of monofilaments formed from hard synthetic resin are implanted at the outer periphery of the bristle base.
Disclosed is a composition for the oral cavity, which has high stain removal efficiency relative to the polishing power. Specifically disclosed is a composition for the oral cavity, which contains fused silica and a tooth polishing agent. The composition for the oral cavity has high stain removal power relative to the polishing power. In other words, the composition for the oral cavity has a high (stain removal power)/(polishing power) value. Consequently, by using the composition for the oral cavity, stain can be efficiently removed from a tooth without unnecessarily damaging the tooth.
Disclosed is a novel proteoglycan-containing material, which has novel use applications and/or an excellent effect. Specifically disclosed is a proteoglycan-containing material which is produced from a fish cartilage and contains an acidic sugar component having a molecular weight of 2000 kDa or more. The proteoglycan-containing material has effects advantageous for skin moisturization and anti-aging, such as an excellent effect of proliferating skin fibroblasts, an excellent effect of enhancing and improving the skin barrier function, an excellent effect of enhancing and improving skin collagen production capability and an excellent effect of inhibiting the thickening of dermises.
Disclosed is an oral care instrument which can maintain a sufficient support strength of a long neck, leaves little residue of a medicant after using, has a low contamination risk from nozzle tip, allows smooth spouting of a medical solution from the beginning, prevents excessive supply of a gelatinous or creamy oral-care composition in the case of flowing the composition in a supply channel inside the same, and contributes to the maintenance of the durability of a manufacturing mold. In the aforesaid oral care instrument which comprises a handle (2), a head (3) and a neck (4), a channel (11) for supplying oral-care composition running within the neck (4) to a nozzle (10) of the head (3) via the handle (2) is formed and the head (3) is connected in a detachable manner to the neck (4). On the inner peripheral wall of the neck (4), multiple ribs (41) projecting in the axial center direction and extending along the axial direction are formed. A tubular member (5) constituting the aforesaid channel (11) for supplying oral-care composition is inserted into the neck (4) so that the outer peripheral face (50) thereof is supported by these ribs (41).
A61C 17/00 - Dispositifs pour nettoyer, polir, rincer ou sécher les dents, les cavités dentaires ou les prothèsesAppareils pour enlever la saliveRéceptacles pour les crachats à usage dentaire
A61C 17/02 - Dispositifs de rinçage ou insufflateurs d'air, p. ex. utilisant des jets de fluide
A46B 11/02 - Brosses à réservoir ou autre système permettant l'application de produits, p. ex. peintures, pâtes, eau avec écoulement du produit du réservoir par pression
This invention relates to a composition that stably contains hesperidin. The present invention provides a composition containing (A) hesperidin, (B) at least one dihydric alcohol selected from the group consisting of ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, and 3-methyl-1,3--butanediol, and (C) a sugar alcohol. In the composition, the decomposition of hesperidin is suppressed and hesperidin isstably contained.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61Q 11/00 - Préparations pour le nettoyage des dents, de la bouche ou des prothèses dentaires, p. ex. dentifricesBains de bouche
Provided are compositions wherein hesperidin has been stably blended and which comprise (A) hesperidin, (B) at least one kind of dihydric alcohol selected from a group composed of ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol and 3-methyl-1,3-butanediol, and (C) a sugar alcohol. With said compositions, hesperidin degradation is suppressed and hesperidin is stably included.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61Q 11/00 - Préparations pour le nettoyage des dents, de la bouche ou des prothèses dentaires, p. ex. dentifricesBains de bouche
99.
AGENT FOR MAINTAINING HEALTHY STATE OF PERIODONTAL TISSUE COMPRISING OLEUROPEIN AND DEGRADED PRODUCT THEREOF
Disclosed is an agent for maintaining the healthy state of the gum, maintaining the healthy state of the gingival, maintaining the healthy state of tissues that support teeth, preventing, treating or ameliorating periodontal diseases, maintaining the healthy state of periodontal tissues, or inhibiting the resorption of alveolar bones. Also disclosed are a food, a beverage, a composition for oral application, and a pharmaceutical composition, each of which contains an active ingredient having the above-mentioned activities. Specifically disclosed are an agent for maintaining the healthy state of the gum, an agent for maintaining the healthy state of the gingiva, an agent for maintaining the healthy state of tissues that support teeth, a prophylactic/treating/ameliorating agent for periodontal diseases, an agent for maintaining the healthy state of periodontal tissues, and an agent for inhibiting the resorption of alveolar bones, each of which comprises at least one component selected from oleuropein and degraded products thereof. Also specifically disclosed are a food, a beverage, a composition for oral application, and a pharmaceutical composition, each of which comprises any one of the above-mentioned agents.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A23L 1/30 - contenant des additifs (A23L 1/308 a priorité);;
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
A61P 1/02 - Préparations stomatologiques, p. ex. médicaments pour le traitement des caries, des aphtes, des périodontites
A61P 19/08 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget
C07H 17/04 - Radicaux hétérocycliques contenant uniquement des atomes d'oxygène comme hétéro-atomes du cycle
Provided is a linear actuator, which has a simple structure, can be manufactured at low cost, furthermore, has less magnetic leakage, and can provide a large inertial force without increasing the number of parts and weight. The linear actuator is provided with: an output shaft (12), which is so supported to a supporting case (11) as to linearly reciprocate; an elastic member (13) which presses the output shaft (12) to the middle position of the linear reciprocation; a permanent magnet (14) fixed to the output shaft (12); a coil (15), which linearly reciprocates the output shaft (12) by having a variable magnetic field operate to the permanent magnet (14), and is fixed to the supporting case (11) such that the coil faces one of the magnetic poles of the permanent magnet (14); a yoke (16), which has a midway section thereof adhered and fixed to the other magnetic pole of the permanent magnet (14), extends to the outer side of the coil (15) along the outer side of the permanent magnet (14) with a space between the permanent magnet (14) and the yoke, has an end section thereof disposed close to the outer side of the coil (15), and is composed of a magnetic material; and a power supply means for forming a variable magnetic field to the coil (15).
A61C 17/00 - Dispositifs pour nettoyer, polir, rincer ou sécher les dents, les cavités dentaires ou les prothèsesAppareils pour enlever la saliveRéceptacles pour les crachats à usage dentaire
A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues
H02K 33/02 - Moteurs avec un aimant, un induit ou un système de bobines à mouvement alternatif, oscillant ou vibrant avec des induits entraînés dans un sens par application d'énergie à un système à une seule bobine et ramenés par une force d'origine mécanique, p. ex. par des ressorts
