The present invention relates to a method of regulating a fibrotic state in cells in cell culture, the cells preferably being fibroblasts, fibrocytes, fibroblast-like cells and/or progenitors of fibroblasts, the method including inducing a fibrotic state in the cells by performing the cell culture under the following conditions: culturing the cells in a scaffold comprising the cells at a density of from 3000 to 6000 cells/mm3, preferably 3400 cells/mm3 cells, for 4 hours to 14 days, wherein the scaffold comprising the fibroblasts is cultured in cell culture medium; and/or culturing the fibroblasts at hypoxic conditions, preferably at an oxygen concentration of less than 21%, more preferably at an oxygen concentration of 20% to 1%, more preferably at an oxygen concentration of 19 % to 1%; most preferably at an oxygen concentration of 18 % to 1%; and/or culturing the fibroblasts at starving conditions. The present invention also relates to a drug-screening method.
The invention relates to an apparatus for accommodating and for analysing, in a spatially and depth-resolved manner, a solid sample material, the apparatus comprising a substantially gas-tight sealed housing (1) with a sample-accommodating region (2) arranged inside the housing (1), the housing (1) comprising a window (3) that is transparent to a laser beam, the apparatus having an inlet device (4) for introducing a fluid flow into the sample-accommodating region (2), and a first outlet device (5) and a second outlet device (6) for discharging the fluid flow, loaded with removed sample material, from the sample-accommodating region (2), the outlet devices (5, 6) being formed in such a way that the ratio between the fluid flow volume flows exiting from the first outlet device (5) and the fluid flow volume flows exiting from the second outlet device (6) is from 100:1 to 5000:1, in particular from 500:1 to 2000:1.
A secondary cell is provided. The secondary cell comprises a solid electrolyte to conduct oxygen ions, a positive electrode configured to be in contact with the solid electrolyte, and a negative electrode configured to be in contact with the solid electrolyte. The positive and the negative electrode comprise a mixed ionic and electronic structure for conducting oxygen ions and electrons. The mixed ionic and electronic structure comprises an ABO3 structure, wherein the A site corresponds to a first chemical element with a first covalent radius, wherein the B site corresponds to a second chemical element with a second covalent radius; and/or a CeMO2 structure, wherein the Ce is Cerium and M is a metal.
A sports equipment (1) for sliding on surfaces having a multi-layered structure comprising a core layer (2) and at least one further layer (3) facing the surface in use, the core layer (2) extending essentially along an entire length of the sports equipment (1) and comprising a matrix material (4) and at least one layer (5) of fibres, wherein the core layer (2) has a central region (6) arranged essentially centrally along the length of the sports equipment (1), with the matrix material (4) being interspersed with the at least one layer (5) essentially along the entire central region (6), and the matrix material (4) is a mineral construction material such as concrete, with the layer (5) of fibres exhibiting pre-tensioning.
The present invention relates to a method for determining a hematocrit level in a blood sample comprising the steps of a ) providing a lateral flow device comprising a blood separation pad, b ) applying a blood sample on the blood separation pad of the lateral flow device, and c ) determining the hematocrit level by comparing the ratio of red blood cells travel distance to the total travel distance on the blood separation pad with a reference ratio.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/86 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir le temps de coagulation du sang
Device for vibrational circular dichroism analysis of an analyte, comprising: —a laser light source for providing a laser beam; —a beam splitter for splitting the laser beam into a sample beam and a reference beam; —a modulator for modulating the polarization of the sample beam and, optionally, the reference beam; —a sample cell and a reference cell; —a sample detector for detecting the sample beam and obtaining a sample beam signal corresponding to an intensity of the sample beam; —a reference detector for detecting the reference beam and obtaining a reference signal corresponding to an intensity of the reference beam; —a subtractor for forming a difference signal of the sample signal and the reference signal. Further, a corresponding method.
G01N 21/3563 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge pour l'analyse de solidesPréparation des échantillons à cet effet
8.
NUCLEAR SPIN RESONANCE SPECTROMETER, METHOD FOR DETECTING A NUCLEAR SPIN RESONANCE AND METHOD FOR DETERMINING A NUCLEAR SPIN RESONANCE SPECTRUM
Method for detecting a nuclear spin resonance, in particular a nuclear magnetic resonance and/or a nuclear quadrupole resonance, of a probe material with a nuclear spin resonance spectrometer (1) with the steps: / Emitting a probe excitation signal generated with the oscillator unit (3); - Exciting the nuclear spin resonance of the probe material (2) by means of the probe excitation signal; - Quenching the first oscillation pulse (8) by activating the quench unit (6); - Deactivating the quench unit (6) after the first oscillation pulse (8) is quenched; - Receiving a response signal from the probe material (2) by means of the oscillator unit (3) responsive to the excitation; - Detecting a delay time (10) of an RF envelope of a second oscillation pulse (9), wherein the delay time (10) depends on the received response signal from the probe material (2); - Comparing the detected delay time (10) to a predefined limit; and - Responsive to confirming that the delay time (10) is below the predefined limit, detecting the nuclear spin resonance of the probe material (2).
G01N 24/08 - Recherche ou analyse des matériaux par l'utilisation de la résonance magnétique nucléaire, de la résonance paramagnétique électronique ou d'autres effets de spin en utilisant la résonance magnétique nucléaire
G01R 33/36 - Détails électriques, p. ex. adaptations ou couplage de la bobine au récepteur
G01R 33/44 - Dispositions ou appareils pour la mesure des grandeurs magnétiques faisant intervenir la résonance magnétique utilisant la résonance magnétique nucléaire [RMN]
A method for producing a test specimen for diffusion-weighted magnetic resonance tomography, the test specimen comprising a plurality of liquid-filled channels embedded in a connecting material (3), the test specimen being formed from a plurality of capillaries (2) by additive manufacturing, the method comprising providing a virtual model of the test specimen defining the course of the capillaries (2) in three-dimensional space, supplying a capillary (2) to a discharging head (12), and repeatedly performing the following sequence of steps: - discharging the capillary (2) from the discharging head (12), - depositing the capillary (2) together with or into the connecting material (3) in accordance with the course defined in the virtual model, the capillary (2) being at least partially embedded in the connecting material (3), and - as and when required, severing and sealing the capillary (2).
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p. ex. modélisation par dépôt de fil en fusion [FDM]
B29C 64/393 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
G01R 33/563 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne de matériaux en mouvement, p. ex. angiographie à écoulement contrasté
G01R 33/58 - Étalonnage des systèmes d'imagerie, p. ex. utilisant des sondes d'essai
B33Y 80/00 - Produits obtenus par fabrication additive
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
10.
METHOD AND KIT FOR ISOTOPE-LABELLING OF A GLUTATHIONE-CONTAINING BIOLOGICAL SAMPLE FOR MASS SPECTROMETRY
A method of stabilising a biological sample including glutathione (GSH) and glutathione disulfide (GSSG), including a) providing the biological sample having GSH and GSSG; b) contacting GSH and GSSG of the sample with a maleimide to obtain maleimide-alkylated GSH; c) separating excess maleimide from maleimide-alkylated GSH and GSSG; d) contacting maleimide-alkylated GSH and GSSG with a reducing agent such as TCEP under conditions which allow reduction of GSSG by the reducing agent such as TCEP to obtain further GSH; and e) contacting maleimide-alkylated GSH and GSH with a heavy isotopologue of the maleimide to obtain a heavy isotopologue of the maleimide-alkylated GSH. A stabilised biological sample is provided containing maleimide- alkylated GSH and a heavy isotopologue thereof, as well as a mass-spectrometric method for quantifying maleimide-alkylated GSH and a heavy isotopologue thereof in a sample and a kit for stabilising a biological sample including GSH and GSSG for mass spectrometric analysis.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
11.
BALANCED-DETECTION INTERFEROMETRIC CAVITY-ASSISTED PHOTOTHERMAL SPECTROSCOPY WITHIN A SINGLE CAVITY
A method and corresponding apparatus for detecting a molecule, in particular a trace gas species, in a sample using photothermal spectroscopy including the steps of
providing a probe laser beam and propagating the probe laser beam to a cavity of a Fabry-Perot interferometer
directing the probe laser beam through the sample in the cavity
providing an excitation laser beam for heating the sample in the cavity
directing the excitation laser beam through the sample in the cavity
detecting the transmitted probe laser beam, which was transmitted from the cavity and
detecting the reflected probe laser beam, which was reflected from the cavity.
G01N 21/17 - Systèmes dans lesquels la lumière incidente est modifiée suivant les propriétés du matériau examiné
G01N 21/39 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant des lasers à longueur d'onde réglable
12.
BIOREACTOR AND METHODS FOR ORGAN-ON-A CHIP APPLICATIONS, PARTICULARLY IN TENDON AND LIGAMENT MODELLING
The present invention relates to a bioreactor for organ-on-a-chip-application, comprising a biochip, a mechanical platform configured for mounting the biochip. The biochip comprises: an elastic biochip material defining a hydrogel compartment and a medium reservoir, the medium reservoir being fluidly connected with the hydrogel compartment via a fluid connection; a first actuation connector located in the elastic biochip material on a first side of the hydrogel compartment, and a second actuation connector located in the elastic biochip material on a second side of the hydrogel compartment opposite the first side; a first pillar and a second pillar configured for fixing a cell-containing hydrogel sample inside the hydrogel compartment to the elastic biochip material defining the hydrogel compartment at first and second positions, respectively; a hydrogel injection port, preferably two hydrogel injection ports, more preferably three hydrogel injections ports, the one or more hydrogel injection ports fluidly connecting the hydrogel compartment to an exterior. The mechanical platform comprises: a driver, preferably a motor; first and second anchors configured for being attached to the first and second actuation connectors, respectively. The driver is configured to drive a reciprocating uniaxial movement of the first anchor relative to the second anchor thereby causing a reciprocating uniaxial stretching of the elastic biochip material defining the hydrogel compartment and a reciprocating uniaxial movement of the first pillar relative to the second pillar. The present invention also relates to a method of producing a heterotypic and multicellular biomimetic tendon structure with such bioreactor.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
13.
ELECTRON BEAM BASED PUMP-PROBE RESONANCE SPECTROSCOPY
Method for time-resolved pump-probe resonance spectroscopy, with the steps: - exposing a sample (4) to a radio-frequency pump pulse (20), wherein the radio-frequency pump pulse (20) drives a resonance, wherein the resonance is an electron spin resonance and/or a nuclear magnetic resonance, wherein the sample (4) is within a magnetic bias field (22); - probing the sample (4) with an electron probe beam (7) from an electron source (6); - detecting a probe beam property of the electron probe beam (7) with a detector unit (8), wherein the probe beam property depends on a magnetic moment (25) of the sample (4), wherein the magnetic moment (25) depends on the driven resonance, wherein the detector unit (8) is configured to detect the probe beam property of the electron probe beam (7) with a temporal resolution for a time-resolved detection of the driven resonance; and determining a property of the resonance, in particular the state of the resonance, preferably a change of the state of the resonance, based on the detected probe beam property.
H01J 37/26 - Microscopes électroniques ou ioniquesTubes à diffraction d'électrons ou d'ions
G01N 24/08 - Recherche ou analyse des matériaux par l'utilisation de la résonance magnétique nucléaire, de la résonance paramagnétique électronique ou d'autres effets de spin en utilisant la résonance magnétique nucléaire
G01N 24/10 - Recherche ou analyse des matériaux par l'utilisation de la résonance magnétique nucléaire, de la résonance paramagnétique électronique ou d'autres effets de spin en utilisant la résonance paramagnétique électronique
G01R 33/60 - Dispositions ou appareils pour la mesure des grandeurs magnétiques faisant intervenir la résonance magnétique utilisant la résonance paramagnétique électronique
The present invention relates to a device (1) for storing thermal energy, the device comprising: a thermochemical storage means (2); a gas guide (2) connected to the thermochemical storage means (2) for supplying a gas to, and for removing the gas from, the thermochemical storage means (2); and a thermal-exchange-medium guide (4) connected to the thermochemical storage means (2) for supplying the thermal-exchange medium to, and for removing the thermal-exchange medium from, the thermochemical storage means (2); wherein the thermochemical storage means (2) comprises a thermochemical storage medium embedded in a matrix; wherein the matrix has a gas diffusion coefficient for the gas of 2.25*10-9m2/s to 4.25*10-9m2/s in a temperature range of -30°C to 300°C, and a maximum expansion ε in the Hooke's Law range of 25% to 300%; wherein the thermochemical storage medium is distributed substantially homogeneously in the matrix.
C09K 5/16 - Substances sujettes à des réactions chimiques lors de leur utilisation
F28D 20/00 - Appareils ou ensembles fonctionnels d'accumulation de chaleur en généralAppareils échangeurs de chaleur de régénération non couverts par les groupes ou
2mm is used as monomers, wherein R is an m-valent hydrocarbon group with up to 100 carbon atoms, one or more of which is optionally replaced with a heteroatom selected from O, N, and S, and m is a whole number ≥ 2; b) an organometallic photoinitiator is used as the polymerization initiator, said photoinitiator being an organometallic complex of an Mn or Fe ion; and c) the polymerization is carried out during the course of a method involving the heating and exposing of the photopolymerizable composition. A homogenous liquid mixture is first produced from all of the components of the composition, and the liquid mixture is then irradiated with a wavelength which is suitable for activating the organometallic photoinitiator in order to cure the composition into the solid polyisocyanurate. The composition is heated to a temperature of at least 50 °C during and/or after the exposure process. The invention also relates to solid polyisocyanurates which can be obtained in this manner.
C08G 18/02 - Polymérisats d'isocyanates ou d'isothiocyanates d'isocyanates ou d'isothiocyanates uniquement
C08G 18/22 - Catalyseurs contenant des composés métalliques
C08G 18/73 - Polyisocyanates ou polyisothiocyanates acycliques
C08G 18/75 - Polyisocyanates ou polyisothiocyanates cycliques cycloaliphatiques
C08G 18/79 - Polyisocyanates ou polyisothiocyanates contenant des hétéro-atomes autres que l'azote, l'oxygène ou le soufre de l'isocyanate ou de l'isothiocyanate de l'azote caractérisés par le polyisocyanate utilisé, celui-ci contenant des groupes formés par oligomérisation d'isocyanates ou d'isothiocyanates
16.
SEPARATION COLUMN MODULE FOR A CHROMATOGRAPH AND CHROMATOGRAPH
The invention relates to a separation column module (1) for a chromatograph, in particular a gas chromatograph, comprising: a chromatographic separation column (2); a temperature control device (3) on the separation column (2) for generating a temporal and/or spatial temperature profile (6) along the separation column (2); and a control unit (4) which is connected to the temperature control device (3) and is designed to electronically control the temperature control device (3), wherein the separation column (2) forms at least one winding (9) and a receiving region (10) inside the at least one winding (9), in which receiving region (10) the control unit (4) is at least partially arranged, wherein the separation column (2) is divided into a plurality of segments (22) and each segment (22) is assigned to its own temperature control element (23) of the temperature control device (3), wherein the temperature control elements (23) are designed to heat and/or cool the segment (22) assigned to them. The invention also relates to a chromatograph (29) having such a separation column module (1).
The invention relates to drive system equipment of an amusement ride, which comprises: means for generating energy; means for storing the generated energy; and means for outputting the stored energy to an external device.
B61B 12/00 - Parties constitutives, détails ou accessoires de systèmes ferroviaires à câbles ou de systèmes "couplables à volonté" non prévus dans les groupes
The invention relates to a method for producing a sintered steel alloyed with a Group 6 element and/or a Group 5 element, having the steps of: • providing a powder mixture, comprising o 1 to 6 wt.% of a pulverulent master alloy prealloy, said master alloy prealloy having a melting point of maximally 1300 °C, o 0.1 to 2 wt.% of a pulverulent Group 6 and/or Group 5 element as an elementary powder or as a ferroalloy powder or as a carbide powder, o 0.1 to 1.0 wt.% of carbon, o up to 1.0 wt.% of a compacting auxiliary agent, and o a remainder of: pulverulent iron or a pulverulent iron alloy, • producing a green body from said powder mixture, and • sintering the green body at a maximum temperature of 1100 to 1250 °C.
The invention relates to a method for manipulating pulsed laser radiation (2), having the following steps: - providing pulsed laser radiation (2); - spatially separating the frequency components of the pulsed laser radiation (2) to a first predetermined extent in a direction perpendicular to a propagation direction of the pulsed laser radiation (2); - guiding pulsed laser radiation (2), spatially separated to the first predetermined extent, to a multiple-pass gas cell (8); - increasing the spectral bandwidth of the pulsed laser radiation (2) in the multiple-pass gas cell (8) for temporal pulse compression of the pulsed laser radiation (2). The invention also relates to a corresponding device (1).
H01S 3/00 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet
H01S 3/23 - Agencement de plusieurs lasers non prévu dans les groupes , p. ex. agencement en série de deux milieux actifs séparés
20.
METHOD AND SYSTEM FOR TESTING THE COATING ADHESION OF A COATING
The invention relates to a method for testing the coating adhesion of a coating of a material sample body. According to one exemplary embodiment, the method comprises the following: bringing the coated material sample body into contact with a sonotrode, wherein the sonotrode comprises a coupling element having a flat contact surface which touches a surface of the sample body; exciting a bending vibration of the material sample body in that the sonotrode carries out a longitudinal vibration, wherein, due to the bending vibration in the plane of the contact surface, a frictional force acts between the coupling element and the material sample body; and examining the surface of the material sample body in order to determine the extent of damage to the coating.
The present invention relates to the use of a triphenylphosphonium carboxylate salt of formula (I) below as a photobase generator in a photopolymerisable composition comprising at least one type of monomer in order to prepare photopolymers by curing the composition by irradiation with light of a suitable wavelength: (I) in which R1and R233, wherein at least one of R1and R233, and in which R332222-O-, -C(=O)-, -O- and -S-; and corresponding new triphenylphosphonium carboxylate salts of formula (I).
C07D 335/16 - Atomes d'oxygène, p. ex. thioxanthones
C07D 403/04 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
The use of a photopolymerizable composition containing a phenol formaldehyde resin, a curing agent, and a photoinitiator in a generative manufacturing method for producing three-dimensional objects by irradiating it layer by layer to cure the composition is described. The use involves the following steps:
a) the composition is heated to a reaction temperature of at least 70° C. before and during curing;
b) the composition contains:
b1) a novolak as said phenol formaldehyde resin,
b2) a formaldehyde derivative stable at the reaction temperature as said curing agent, and
b3) a photoacid generator as said photoinitiator; and
c) curing of the composition is conducted at normal pressure;
with the proviso that the curing agent is not an amine-containing formaldehyde derivative.
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
B29K 61/00 - Utilisation de polymères de condensation d'aldéhydes ou de cétones comme matière de moulage
A liquid-liquid centrifugal extractor, including a shaft, a first mixing chamber with at least one first inlet for a first and a second liquid, the first and the second liquid being mixed by rotating the shaft, a separator mounted on the shaft for separating the first from the second liquid, a first collecting chamber for extracting one of the first and second liquid, wherein the first mixing chamber extends along a first axial section of the shaft and the separator extends along a second axial section of the shaft, the second axial section of the shaft being spaced from the first axial section in axial direction of the shaft.
B04B 5/12 - Centrifugeurs dans lesquels l'action centrifuge agissant dans un récipient stationnaire est obtenue par des organes rotatifs autres que des tambours
24.
METHOD AND DEVICE FOR INTERFERENCE VARIABLE COMPENSATION DURING THE POSITIONING OF A SAMPLE SUPPORT
A method and device for interference variable compensation during the positioning of a sample support during probe microscopy. The method includes measuring a distance to a first side of the sample support using a first distance sensor of a sensor support, and measuring a distance to a second side of the sample support opposite the first side using a second distance sensor of the sensor support, the distances being determined substantially in parallel with a first axis; measuring a distance to a third side of the sample support using a third distance sensor of the sensor support, and measuring a distance to a fourth side of the sample support opposite the third side using a fourth distance sensor of the sensor support, the distances being determined substantially in parallel with a second axis different from the first axis; positioning the sample support relative to the sensor support using a piezopositioner.
The present invention relates to a device (1;10;15) for the storage and/or transport of cells, in particular cell aggregates, wherein the device comprises at least one chamber (2) with a base (5;11) and a top (6;12), wherein the top (6;12) is situated on the opposite to the base (5;11), wherein the base (5; 11) is formed by a substrate comprising at least one recess (7) for collecting a fluid, wherein the distance (8) between the base (5;11) and the top (6; 12) of the at least one chamber (2) is less than the width (9) of the at least one recess (7), and wherein the width (9) of the at least one recess (7) is the smallest line segment between two opposite points passing through the center of the base area of the at least one recess (7).
C12M 1/32 - Inoculateur ou échantillonneur du type à champs multiples ou en continu
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
A thermoplastic poly(urethane-urea) polyadduct (I) with sterically hindered urea groups used in an electrospinning method for producing vascular prostheses:
A thermoplastic poly(urethane-urea) polyadduct (I) with sterically hindered urea groups used in an electrospinning method for producing vascular prostheses:
I, M, C1 and C2 represent bivalent radicals linked via a urethane or urea moiety;
I and C2 represent a bivalent, saturated or unsaturated, aliphatic, alicyclic or aromatic radical with 1-20 carbon atoms derived from (I): a diisocyanate; or (C2): from a diol, diamine or amino alcohol;
M represents a bivalent radical of an aliphatic polyether, polyester or polycarbonate derived from a macrodiol having Mn≥500;
C1 represents a bivalent, saturated or unsaturated, aliphatic or alicyclic radical with 1-30 carbon atoms derived from a diamine or amino alcohol with ≥1 sterically hindered secondary amino group through removal of one N-linked hydrogen atom of the diamine or one N-linked and the O-linked hydrogen atoms of the amino alcohol.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
C08G 18/24 - Catalyseurs contenant des composés métalliques de l'étain
C08G 18/73 - Polyisocyanates ou polyisothiocyanates acycliques
D01D 5/00 - Formation des filaments, fils ou similaires
D01F 6/78 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de produits de copolycondensation
A micro-electromechanical system (1) comprising: a sensor device (2), with a measuring deformer (3) exhibiting an effective temperature T1; a high-frequency resonator (4) that is mechanically coupled to the sensor device (2) and can interact with the measuring deformer (3); an energy converter (7) that is operatively connected to the high-frequency resonator (4) and is configured to excite the high-frequency resonator (4) into a vibration state, wherein, through the interaction of the vibrating high-frequency resonator (4) with the measuring deformer (3), energy can be transferred from the measuring deformer (3) to the high-frequency resonator (4) in such a manner that the measuring deformer (3) after the energy transfer exhibits an effective temperature T2 lower than T1.
B81B 3/00 - Dispositifs comportant des éléments flexibles ou déformables, p. ex. comportant des membranes ou des lamelles élastiques
G01C 19/5712 - Dispositifs sensibles à la rotation utilisant des masses vibrantes, p. ex. capteurs vibratoires de vitesse angulaire basés sur les forces de Coriolis utilisant des masses entraînées dans un mouvement de rotation alternatif autour d'un axe les dispositifs comportant une structure micromécanique
G01Q 60/24 - Microscopie à forces atomiques AFM [Atomic Force Microscopy] ou appareils à cet effet, p. ex. sondes AFM
H10N 30/30 - Dispositifs piézo-électriques ou électrostrictifs à entrée mécanique et sortie électrique, p. ex. fonctionnant comme générateurs ou comme capteurs
28.
METHOD FOR PRODUCING PRODUCTS BASED ON NON-WOODY BIOMASS AS RAW MATERIAL
The invention relates to a method for producing products based on non-woody biomass as raw material, characterised in that non-woody biomass which contains cellulose, hemicelluloses and lignin and is in the form of particles is subjected to an extraction treatment with an extractant which comprises one or more organic solvents in an organic aqueous mixture of the solvent or solvents with water, wherein the content of fatty acids in the particles is reduced by the extraction treatment of the particles with the solvent by at least 70%, measured as hexanal content in wt. % after accelerated ageing for 72 hours at 90° C., but the content of cellulose, hemicelluloses and lignin is substantially preserved in this extraction treatment.
D21C 3/20 - Réduction en pâte des matières contenant de la cellulose avec des solvants organiques
A23K 10/32 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons à base d’hydrolysats de bois ou de paille
This application relates to a measuring device for characterising a saw band (11) of a band saw machine. According to one embodiment, the measuring device has the following: a first inductive distance sensor (30), which is designed to generate a sensor signal that represents a distance between a sensor position and a front side of the saw band (11), on which saw teeth (101, 102) are present; a support roller (32); and a preload mechanism, which is designed to press the roller against a rear side of the saw band (11).
The present invention relates to a computer-implemented method for use in a computer-aided production system (100), in particular for controlling an operation of a computer-aided production system (100), and to a production system (100), wherein the method comprises at least the following steps: a1) providing component data that are assigned to one or more components (101), wherein the component data contain information relating to two or more feature groups (106) that are assigned to one or more components, wherein each component in relation to which data are provided is assigned at least one feature group (106), wherein each feature group (106) comprises a group of features which at least partially define the component (101) to which the feature group (106) is assigned, and wherein each feature group (106) is assigned feature group data, a2) acquiring operating data of the production system (100) and assigning the acquired operating data of the production system (100) to at least one feature group (106), b) selecting (S2) at least one feature group (106), c) providing (S3) at least a proportion of the feature group data that are assigned to the at least one selected feature group (106), d) evaluating (S4) the provided feature group data and determining a value of at least one variable that characterizes the selected feature group (106), and e) storing, outputting and/or further processing the at least one value ascertained in step d).
G05B 19/409 - Commande numérique [CN], c.-à-d. machines fonctionnant automatiquement, en particulier machines-outils, p. ex. dans un milieu de fabrication industriel, afin d'effectuer un positionnement, un mouvement ou des actions coordonnées au moyen de données d'un programme sous forme numérique caractérisée par l'utilisation de l'entrée manuelle des données [MDI] ou par l'utilisation d'un panneau de commande, p. ex. commande de fonctions avec le panneauCommande numérique [CN], c.-à-d. machines fonctionnant automatiquement, en particulier machines-outils, p. ex. dans un milieu de fabrication industriel, afin d'effectuer un positionnement, un mouvement ou des actions coordonnées au moyen de données d'un programme sous forme numérique caractérisée par les détails du panneau de commande ou par la fixation de paramètres
G05B 19/4093 - Commande numérique [CN], c.-à-d. machines fonctionnant automatiquement, en particulier machines-outils, p. ex. dans un milieu de fabrication industriel, afin d'effectuer un positionnement, un mouvement ou des actions coordonnées au moyen de données d'un programme sous forme numérique caractérisée par la programmation de pièce, p. ex. introduction d'une information géométrique dérivée d'un dessin technique, combinaison de cette information avec l'information d'usinage et de matériau pour obtenir une information de commande, appelée programme de pièce, pour la machine à commande numérique [CN]
32.
METHOD AND DEVICE FOR CONTROLLING A LITHOGRAPHY-BASED ADDITIVE MANUFACTURING DEVICE
In a method of controlling a lithography-based additive manufacturing device capable of manufacturing a three-dimensional component from a plurality of volume elements, a check is made to determine whether the volume elements are entirely within the three-dimensional virtual model by identifying at least first and second boundary points of the volume element or virtual model in x-y planes spaced apart in the z-direction, and the volume element in question is provided for the manufacturing process only if it is within the model with respect to the first and second boundary points.
B29C 64/386 - Acquisition ou traitement de données pour la fabrication additive
B29C 64/135 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque la source d’énergie étant concentrée, p. ex. lasers à balayage ou sources lumineuses focalisées
The invention relates to a connecting element which is designed to be mounted on a bicycle and to establish a releasable connection between the bicycle and an underside of a rucksack (3) carried by a bicycle rider (2) during the journey and to exert a spring action between the bicycle and the rucksack (3), the connecting element (1) comprising the following parts: at least one means (1a, 1a') for fastening the connecting element on the frame (4) and/or on the seat post and/or on a rear-wheel luggage rack (7) of the bicycle; at least one spring means (1b-ii) connected to the at least one fastening means (1a) for exerting the spring action between the bicycle and the rucksack (3); and at least one means (1c) connected to the spring means (1b-ii) for establishing a releasable connection to the rucksack (3).
Process for the reversible thermochemical storage of energy and release of energy, wherein, for the storage of energy, orthoboric acid is converted into boric oxide, metaboric acid or boric oxide and metaboric acid by loss of water, wherein, for the release of energy, boric oxide or metaboric acid or boric oxide and metaboric acid are converted into orthoboric acid by reaction with water, wherein the reactions take place in a suspension medium, wherein for the reversible storage of energy, orthoboric acid is present suspended in the suspension medium, and wherein the suspension medium containing orthoboric acid is brought to a temperature at which water loss occurs via an energy source, wherein for the reversible thermochemical release of energy boric oxide and/or metaboric acid are present suspended in a suspension medium, wherein water is added to the suspension medium containing boric oxide or metaboric acid or boric oxide and metaboric acid so that the reaction proceeds to orthoboric acid, wherein the heat generated in this process is dissipated to a heat consumer.
C09K 5/16 - Substances sujettes à des réactions chimiques lors de leur utilisation
C01B 35/10 - Composés contenant du bore et de l'oxygène
F28D 20/00 - Appareils ou ensembles fonctionnels d'accumulation de chaleur en généralAppareils échangeurs de chaleur de régénération non couverts par les groupes ou
35.
METHOD FOR DETERMINING AT LEAST ONE SPEED COMPONENT OF A FLUID STREAM
The application relates to a method for determining at least one speed component of a fluid stream, in particular for laser Doppler anemometry, the method having at least the steps of: —providing at least a first part-beam and a second part-beam; —directing the first part-beam along a first optical path and directing the second part-beam along a second optical path onto a superimposition region within the fluid stream so that the first optical path and the second optical path intersect in the superimposition region; —detecting a Doppler-shifted first part-beam scattered light signal, which was back-scattered by tracer particles in the fluid stream in the superimposition region, at least partially following the first optical path; —detecting a Doppler-shifted solid angle scattered light signal, which was scattered by the tracer particles in the superimposition region into a path different at least from the first optical path and from the second optical path. The application also relates to a corresponding device.
G01P 5/26 - Mesure de la vitesse des fluides, p. ex. d'un courant atmosphériqueMesure de la vitesse de corps, p. ex. navires, aéronefs, par rapport à des fluides en mesurant l'influence directe du courant de fluide sur les propriétés d'une onde optique de détection
An optical device for controlling a light beam includes a beam shaping unit for increasing the uniformity of the spatial intensity profile of the light beam; —a lens system; and —a focusing unit. The lens system comprises a first lens and a second lens, and each of the first lens and the second lens comprises a stepped optical surface formed by active sections and reset sections alternating with each other. The active sections stepwise form a surface profile, which is aspheric, and the stepped optical surface of the first lens faces the stepped optical surface of the second lens.
A eukaryotic cell which is engineered to express a synthetic formolase (FLS) pathway comprising a recombinant FLS to biotransform formaldehyde into dihydroxyacetone.
The invention relates to a sensor device which has a carrier material, in particular a piezoelectric carrier material. The sensor device also comprises: at least one interdigital transducer which is designed as a transmitter (IDTs) and as a receiver (IDTe) and is positioned on the carrier material; or at least one interdigital transducer which is designed as a transmitter (IDTs) and at least one interdigital transducer which is designed as a receiver (IDTe) and is also positioned on the carrier material. The sensor device also comprises at least one mechanical resonator (MR) which is positioned on the carrier material at a distance (A) from the IDTs and at a distance (B) from the IDTe, wherein the sensor device is designed so that a surface wave emitted by the IDTs as a transmission signal causes the MR to vibrate mechanically and a surface wave emitted by the vibrating MR travels in the direction of the IDTe as a received signal and triggers a measurement signal in said IDTe.
A method of build-up welding a powdery or wire-shaped material onto a workpiece, which is preferably a flat substrate, by means of a device which comprises a substantially rod-shaped electrode, the electrode having at least one material feed channel extending in its interior, the device comprising a nozzle surrounding the electrode, the method comprising the following steps:
forming the arc as a transferred arc between the electrode and the workpiece or as a free-standing arc between the electrode and the nozzle,
flooding the working gas area with a working gas to constrict the arc in the direction of the workpiece,
feeding the powdery or wire-shaped material into the constricted arc and
moving the device across the workpiece as the powdery or wire-shaped material is being fed into the constricted arc.
RLRL 45454545454545 is an intensity of the light in the linear 135° polarization orientation. The invention also relates to a method using an imaging ellipsometer (1).
G01B 11/06 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur pour mesurer l'épaisseur
The invention relates to a linear Reluctance actuator (6) comprising a stator (18) carrying at least one coil (32), and a rotor (24), the coil (32) being in the form of a double-wound winding and the linear actuator (6) having at least one return element (74) by means of which the rotor (24) can be brought into a defined initial position after a rotational movement.
H02K 33/02 - Moteurs avec un aimant, un induit ou un système de bobines à mouvement alternatif, oscillant ou vibrant avec des induits entraînés dans un sens par application d'énergie à un système à une seule bobine et ramenés par une force d'origine mécanique, p. ex. par des ressorts
H02K 41/035 - Moteurs à courant continuMoteurs unipolaires
42.
CYANATE ESTERS AS MONOMERS IN POLYMERISABLE COMPOSITIONS
nn are used as monomers, in which R is an n-value hydrocarbon group containing up to 50 carbon atoms and n is an integer ≥ 2; b) an organometallic photoinitiator is used as polymerisation initiator; c) a compound comprising at least one acidic hydrogen atom is used as co-catalyst; and d) the polymerisation is performed during the course of a 3D printing method comprising heating and exposure of the photopolymerisable composition, all components first being heated to a temperature > 70°C in order to obtain a homogeneous liquid mixture which is then irradiated at at least the same temperature with a wavelength corresponding to the polymerisation initiator in order to obtain a three-dimensional solid body.
C08G 73/06 - Polycondensats possédant des hétérocycles contenant de l'azote dans la chaîne principale de la macromoléculePolyhydrazidesPolyamide-acides ou précurseurs similaires de polyimides
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
22222222] . (bpy), where bpe represents 1,2-bis(4-pyridyl)ethane, Hbtc represents benzene-1,3,5-tricarboxylic acid and bpy represents 4,4'-bipyridine. The invention also relates to a method for the adsorptive removal of nitrate from an aqueous solution by means of said metal-organic framework, regeneration of the nitrate-containing adsorbent and to the use of these compounds as adsorbents for nitrate.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
A catalyst comprising a support and a catalytically active coating, wherein the catalytically active coating comprises a metal sulfide, wherein the support is zinc(II) oxide, wherein the proportion of metal sulfide is between 15% and 30% by weight, preferably between 15% and 25% by weight and particularly preferably between 15% and 20% by weight, based on zinc(Il) oxide.
C07C 29/153 - Préparation de composés comportant des groupes hydroxyle ou O-métal liés à un atome de carbone ne faisant pas partie d'un cycle aromatique à six chaînons par réduction exclusivement des oxydes de carbone avec de l'hydrogène ou des gaz contenant de l'hydrogène caractérisée par le catalyseur utilisé
A process for the production of methanol (CH3OH) from carbon dioxide (CO2) and hydrogen (H2), wherein CO2 is reacted with H2 over a manganese-promoted molybdenum(IV) sulfide catalyst; as well as a catalyst for such a process and a production process for the catalyst.
C07C 29/153 - Préparation de composés comportant des groupes hydroxyle ou O-métal liés à un atome de carbone ne faisant pas partie d'un cycle aromatique à six chaînons par réduction exclusivement des oxydes de carbone avec de l'hydrogène ou des gaz contenant de l'hydrogène caractérisée par le catalyseur utilisé
The invention relates to a device for connecting a cannula to a container under reduced pressure, in particular a blood culture flask, including an inflow opening for connecting to the cannula or to a connection tube connected to the cannula, an outflow opening for connecting to a hollow pin for piercing a closure of the container, and a tight fluidic connection of the inflow opening to the outflow opening. According to the invention, a reservoir which is separated from the fluidic connection and contains a specified gas quantity is connected to the fluidic connection with the interposition of a valve which is preferably open towards the fluidic connection.
A61B 5/154 - Dispositifs de prélèvement d'échantillons de sang spécialement adaptés pour le prélèvement d'échantillons de sang veineux ou artériel, p. ex. par des seringues utilisant des moyens préalablement mis sous vide
A61B 5/15 - Dispositifs de prélèvement d'échantillons de sang
The present invention relates to a method for producing polymers by exposure to light of a photopolymerisable monomer or prepolymer composition comprising at least one tetrakisacylgermane as a radical photoinitiator, characterised in that a) the composition comprises tetrakis(2,6-dimethoxybenzoyl)germane of formula (I) below as the photoinitiator; and b) the polymerisation of the composition is initiated by exposure to light at a wavelength of at least 440 nm.
C08F 2/50 - Polymérisation amorcée par énergie ondulatoire ou par rayonnement corpusculaire par la lumière ultraviolette ou visible avec des agents sensibilisants
C08F 4/72 - MétauxHydrures métalliquesComposés organiques de métalLeur utilisation comme précurseurs de catalyseurs choisis parmi les métaux non prévus dans le groupe
Sports device (1) for sliding on surfaces, having a multi-layer structure comprising a core layer (2), and at least one further layer (3) that faces the surface during operation, wherein the core layer (2) extends substantially along an entire length of the sports device (1) and comprises a matrix material (4) and at least one layer (5) of fibres, wherein the core layer (2) has a central region (6) arranged substantially centrally along the length of the sports device (1), wherein the matrix material (4) is traversed by the at least one layer (5) substantially along the entire central region (6), and the matrix material (4) is a mineral construction material such as concrete, wherein the layer (5) of fibres has pretensioning.
Microfluidic device (1) comprising at least one fluid channel (2) comprising at least one inlet (3), wherein said at least one fluid channel (2) is fluidly connected to a first sensor (4) downstream of said at least one fluid inlet (3), wherein the first sensor (4) comprises at least one sensor cathode (5) and at least one sensor anode (6) formed on an essentially electrically isolating substrate (7), wherein the sensor cathode (5) and the sensor anode (6) are spaced apart by a gap (8) formed on the electrically isolating substrate (7), and wherein at least one analyte capturing molecule (9) is immobilized in the gap (8) on the substrate (7), wherein the at least one capturing molecule (9) is adapted to capture at least one analyte (10) of a fluid sample introduced into the inlet (3) and transported to the first sensor (4).
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
H01M 8/16 - Éléments à combustible biochimique, c.-à-d. éléments dans lesquels des micro-organismes agissent comme catalyseurs
H01M 8/2455 - Groupement d'éléments à combustible, p. ex. empilement d'éléments à combustible avec des réactifs liquides, solides ou chargés en électrolyte
Memristive logic gate circuit, comprising a first memristive device (1), representing a first input node A of the logic gate circuit, a second memristive device (2), representing a second input node B of the logic gate circuit, and a third memristive device (3), representing an output node F of the logic gate circuit, wherein the first memristive device (1) and the second memristive device (2) are connected in series between a positive supply voltage terminal Vx (7) and a negative supply voltage terminal −Vx (8), wherein a connection point (6) is formed between the first memristive device (1) and the second memristive device (2), and wherein the third memristive device (3) is provided between the connection point (6) and a Ground contact (9).
Device (1) for vibrational circular dichroism analysis of an analyte, comprising: - a laser light source (2) for providing a laser beam (3); - a beam splitter (5) for splitting the laser beam (3) into a sample beam (6a) and a reference beam (6b); - a modulator (11) for modulating the polarization of the sample beam (6a) and, optionally, the reference beam (6b); - a sample cell (14a) and a reference cell (14b); - a sample detector (15a) for detecting the sample beam (6a) and obtaining a sample beam signal corresponding to an intensity of the sample beam (6a); - a reference detector (15b) for detecting the reference beam (6b) and obtaining a reference signal corresponding to an intensity of the reference beam (6b); - a subtractor (16) for forming a difference signal of the sample signal and the reference signal. Further, a corresponding method.
G01N 21/35 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge
A thermoplastic poly(urethane-urea) polyadduct with sterically hindered urea groups of the following Formula (I):
A thermoplastic poly(urethane-urea) polyadduct with sterically hindered urea groups of the following Formula (I):
—[I-M-(I—C1)a—(I-M)b-(I—C2)c]n- (I)
A thermoplastic poly(urethane-urea) polyadduct with sterically hindered urea groups of the following Formula (I):
—[I-M-(I—C1)a—(I-M)b-(I—C2)c]n- (I)
I, M, C1 and C2 each representing bivalent residues linked to each other via a urethane or urea moiety. In the residues I, C1 and C2, when more than four carbon atoms are present, optionally at least one of them is substituted by a heteroatom selected from oxygen and nitrogen. Optionally at least one of the residues I, M, C1 and C2 includes one or more ester moieties. a, b and c each independently represent an integer from 0 to 10, and n is a number ≥3 representing the number of blocks in the polyadduct. Within each separate block a+c≥1, and in all blocks together at least one a≥1 and at least one c≥1.
C08G 18/12 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle utilisant plusieurs composés contenant un hydrogène actif dans le premier stade de la polymérisation
mn are not identical, and the outputs of each subpixel (3) are connected to form M output lines (4), wherein each output line (4) sums the photodetector currents produced by the m-th subpixels (3) in all N pixels (2, 2′, 2″) and delivers a detector current of Formel (I), to be used for recognizing and classifying the optical image.
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
The invention relates to a stoichiometric salt of a tetracarboxylic acid and a diamine of the following general formula (I),
The invention relates to a stoichiometric salt of a tetracarboxylic acid and a diamine of the following general formula (I),
The invention relates to a stoichiometric salt of a tetracarboxylic acid and a diamine of the following general formula (I),
wherein R1 is selected from tetravalent residues of butane, cyclobutane, cyclopentane, cyclohexane, tetrahydrofurane and benzophenone and R2 is selected from divalent residues of unbranched, branched or cyclic aliphatic hydrocarbons with 3 to 15 carbon atoms, with the proviso that the salt of the formula (I) is water-soluble and is selected from compounds (1) to (28); and to the polyimides prepared from these salts by polycondensation.
The invention relates to a method for preparing a tensile test on an elongate, more particularly fibrous, specimen, for example on a collagen fibril, comprising the steps of:—providing the elongate specimen;—attaching a handling particle to the elongate specimen;—providing a force sensor, on which a retainer for the handling particle on the elongate specimen is disposed;—connecting a handling apparatus to the handling particle on the elongate specimen; and—connecting the handling particle on the elongate specimen to the retainer on the force sensor by means of the handling apparatus. The invention also relates to a method and a device for performing a tensile test on an elongate specimen.
G01N 3/14 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression engendrés par poids mort, p. ex. penduleRecherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression engendrés par la tension d'un ressort
G01N 1/36 - Enrobage ou montage analogue d'échantillons
G01N 3/08 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression
G01N 3/317 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant une force unique et brève engendrée par des moyens électromagnétiques
The present invention relates to a microfluidic device (1), preferably for producing a three-dimensional cell culture, having at least one chamber (2), and a fluid channel (3) which flows through at least part of the chamber (2) in order to provide a fluid stream which flows through the chamber (2) preferably continuously, wherein the chamber (2) is connected to a loading opening (4) and via the loading opening (4) can be loaded with hydrogel up to a desired fill level, characterized in that the chamber (2) comprises a main chamber (5) and a secondary chamber (6) connected to the main chamber (5), wherein, when the chamber (2) is being loaded with hydrogel up to the desired fill level, the secondary chamber is at least partially filled with hydrogel backed up from the main chamber (5).
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
The present invention provides a polypeptide having peroxidase activity and comprising an amino acid sequence having at least 70% sequence identity to SEQ ID NO: 3, wherein said amino acid sequence comprises at least one amino acid exchange compared to SEQ ID NO: 1, wherein said at least one amino acid exchange is an exchange of the amino acid P146 or of the amino acid N275 of SEQ ID NO: 1. The invention further relates to a nucleic acid molecule comprising a sequence encoding said polypeptide, an expression vector comprising said nucleic acid molecule, and a host cell comprising said expression vector. Moreover, methods for producing said polypeptide and compositions and kits comprising said polypeptides are provided.
The present invention relates to a microfluidic device (1) for cultivating cells, in particular for generating brain organoids, comprising at least two fluid channels (2) positioned essentially opposite to each other and a main chamber (3) located between the fluid channels (2), wherein the main chamber (3) comprises at least one preferably sealable access opening, and each of the at least two fluid channels (2) is fluidly connected to the main chamber (3) at at least one point of contact (4), wherein a slotted structure (5) is provided at each point of contact (4) separating the main chamber (3) from the respective fluid channel (2), wherein the slotted structure (5) is permeable to a liquid.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
The present invention provides methods for producing a heme pe-roxidase from inclusion bodies (IBs) comprising the steps of: providing the heme peroxidase in the form of IBs, solubilizing said IBs, transferring said solubilized IBs into a refolding buffer to obtain a refolding mix, adding a heme cofactor to said refolding mix, wherein the addition of the heme cofactor to the refolding mix is distributed over a time period of at least 1 hour. The invention further provides methods for producing heme peroxidase products.
The invention relates to an apparatus for accommodating and for analysing, in a spatially and depth-resolved manner, a solid sample material, the apparatus comprising a substantially gas-tight sealed housing (1) with a sample-accommodating region (2) arranged inside the housing (1), the housing (1) comprising a window (3) that is transparent to a laser beam, the apparatus having an inlet device (4) for introducing a fluid flow into the sample-accommodating region (2), and a first outlet device (5) and a second outlet device (6) for discharging the fluid flow, loaded with removed sample material, from the sample-accommodating region (2), the outlet devices (5, 6) being formed in such a way that the ratio between the fluid flow volume flows exiting from the first outlet device (5) and the fluid flow volume flows exiting from the second outlet device (6) is from 100:1 to 5000:1, in particular from 500:1 to 2000:1.
H01J 49/04 - Dispositions pour introduire ou extraire les échantillons devant être analysés, p. ex. fermetures étanches au videDispositions pour le réglage externe des composants électronoptiques ou ionoptiques
62.
BALANCED-DETECTION INTERFEROMETRIC CAVITY-ASSISTED PHOTOTHERMAL SPECTROSCOPY WITHIN A SINGLE CAVITY
A method for detecting a molecule, in particular a trace gas species, in a sample using photothermal spectroscopy comprising the steps of: - providing a probe laser beam (7) and propagating the probe laser beam (7) to a cavity (5) of a Fabry-Perot interferometer (2); - directing the probe laser beam (7) through the sample in the cavity (5); - providing an excitation laser beam (10) for heating the sample in the cavity (5); - directing the excitation laser beam (10) through the sample in the cavity (5); - detecting the transmitted probe laser beam (11), which was transmitted from the cavity (5); - detecting the reflected probe laser beam (14), which was reflected from the cavity (5). Further, a corresponding apparatus (1).
G01N 21/17 - Systèmes dans lesquels la lumière incidente est modifiée suivant les propriétés du matériau examiné
G01N 21/45 - RéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant des méthodes interférométriquesRéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant les méthodes de Schlieren
63.
METHOD FOR PREPARING AN ADHESIVE TAPE OR MOLDING MASS
A polymerizable composition which may be used as an adhesive mass in a method for preparing an adhesive tape or as molding mass in a method for preparing molded articles is provided. The polymerizable composition contains: A) a thermal cationic initiator, or B) a combination of a cationic photoinitiator and a thermal free-radical initiator for inducing the polymerization of the cationically polymerizable monomers in such an amount that the heat energy released during polymerization is sufficient for cleaving the thermal initiator. The adhesive mass is curable via a local impulse a) of thermal energy orb) of thermal energy and/or radiation energy through frontal polymerization; or the molding mass is initially prepared by mixing all components and then molded into the desired shape, whereafter its frontal polymerization is induced by a local impulse a) of thermal energy and/or b) of radiation energy in order to prepare a cured molded article.
A liquid-liquid centrifugal extractor (1), comprising: a shaft (2), a first mixing chamber (5) with at least one first inlet (14) for a first and a second liquid, the first and the second liquid being mixed by rotating the shaft (2), a separator (13) mounted on the shaft (2) for separating the first from the second liquid, a first collecting chamber (6) for extracting one of the first and second liquid, wherein the first mixing chamber (5) extends along a first axial section (2A) of the shaft (2) and the separator (13) ex- tends along a second axial section (2B) of the shaft (2), the second axial section (2B) of the shaft being spaced from the first axial section (2A) in axial direction of the shaft (2).
The invention relates to the use of a photopolymerizable composition comprising a phenol-formaldehyde resin, a curing agent and a photoinitiator in an additive manufacturing method for production of three-dimensional articles by means of layer-by-layer exposure for curing of the composition, having the characterizing features that a) the composition is heated to a reaction temperature of at least 70°C before and during the curing; b) the composition comprises b1) a novolak as phenol-formaldehyde resin, b2) a formaldehyde derivative which is stable at the reaction temperature as curing agent, and b3) a photoacid former as photoinitiator; and c) the curing of the composition is conducted at standard pressure; with the proviso that the curing agent is not an amine-containing formaldehyde derivative.
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
66.
METHOD AND DEVICE FOR INTERFERENCE VARIABLE COMPENSATION DURING THE POSITIONING OF A SAMPLE SUPPORT
The invention relates to a method for interference variable compensation during the positioning of a sample support (2), in particular during probe microscopy, said method comprising the following steps: measuring a distance (dx1) to a first side of the sample support (2) using a first distance sensor (X1) of a sensor support (3), and measuring a distance (dx2) to a second side of the sample support (2) opposite the first side using a second distance sensor (X2) of the sensor support (3), the distances (dx1, dx2) being determined substantially in parallel with a first axis (x); measuring a distance (dy1) to a third side of the sample support (2) using a third distance sensor (Y1) of the sensor support (3), and measuring a distance (dy2) to a fourth side of the sample support (2) opposite the third side using a fourth distance sensor (Y2) of the sensor support (3), the distances (dy1, dy2) being determined substantially in parallel with a second axis (y) different from the first axis (x); positioning the sample support (2) relative to the sensor support (3) using a piezopositioner (1). The invention also relates to a corresponding device (10).
A method for analyzing or optimizing the operation of waste incinerator systems. The content of CO2 is measured in the exhaust gas and is used to determine the ratio of biogenic carbon to fossil carbon in the incinerated waste, if necessary after resetting to the CO2 reference quantity. The variability of the CO2 reference or the ratio of biogenic carbon to fossil carbon in the incinerated waste is determined and recorded according to quantity and duration. When optimizing the operation, the location of the waste in the bunker, from which the incinerated waste originates with a composition or variability that has now been ascertained using the method, is used to further remove or mix the waste.
The invention relates to a micro-electromechanical system (1) comprising: a sensor device (2) with a measuring transducer (3) which has an effective temperature T1; a high-frequency resonator (4) which is mechanically coupled to the sensor device (2) and can interact with the measuring transducer (3); an energy converter (7) which is operatively connected to the high-frequency resonator (4) and is designed to excite the high-frequency resonator (4) into a vibrational state, wherein energy can be transmitted from the measuring transducer (3) to the high-frequency resonator (4) as a result of the interaction between the vibrating high-frequency resonator (4) and the measuring transducer (3) such that the measuring transducer (3) has an effective temperature T2 which is lower than T1 after the energy transmission.
G01P 15/08 - Mesure de l'accélérationMesure de la décélérationMesure des chocs, c.-à-d. d'une variation brusque de l'accélération en ayant recours aux forces d'inertie avec conversion en valeurs électriques ou magnétiques
G01C 25/00 - Fabrication, étalonnage, nettoyage ou réparation des instruments ou des dispositifs mentionnés dans les autres groupes de la présente sous-classe
G01P 21/00 - Essai ou étalonnage d'appareils ou de dispositifs couverts par les autres groupes de la présente sous-classe
G01P 15/097 - Mesure de l'accélérationMesure de la décélérationMesure des chocs, c.-à-d. d'une variation brusque de l'accélération en ayant recours aux forces d'inertie avec conversion en valeurs électriques ou magnétiques au moyen d'éléments vibrants
G01Q 60/24 - Microscopie à forces atomiques AFM [Atomic Force Microscopy] ou appareils à cet effet, p. ex. sondes AFM
69.
METHOD FOR THE CHIRPED PULSE AMPLIFICATION OF A TRAIN OF OPTICAL PULSES
The disclosure concerns a method for the chirped pulse amplification of a train of optical pulses, comprising at least the steps: - providing for the train of pulses; - stretching (2) the train of pulses in the time domain; - modulating (3) the amplitude and/or the phase of the pulses such that spectral modes of the pulses are at least partially suppressed; - amplifying (4) the train of pulses and forming (4) a burst; - compressing (5) the pulses in the time domain; - parametrically converting (6) the pulses by optical parametric amplification such that the suppressed spectral modes are at least partially regained. Further, the disclosure concerns an according device (1).
H01S 3/00 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet
H01S 3/23 - Agencement de plusieurs lasers non prévu dans les groupes , p. ex. agencement en série de deux milieux actifs séparés
H01S 3/08 - Structure ou forme des résonateurs optiques ou de leurs composants
H01S 3/139 - Stabilisation de paramètres de sortie de laser, p. ex. fréquence ou amplitude par commande de la position relative ou des propriétés réfléchissantes des réflecteurs de la cavité
The invention relates to a method for controlling a lithography-based additive manufacturing device, by which a three-dimensional component can be produced from a plurality of volume elements. In said method, it is verified whether the volume elements are located completely within the three-dimensional virtual model, in that at least first and second edge points of the volume element or the virtual model are identified in x-y planes, which are spaced apart in the z direction, and the respective volume element is provided for the manufacturing process only when it is located within the model with respect to the first and second edge points.
B29C 64/135 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque la source d’énergie étant concentrée, p. ex. lasers à balayage ou sources lumineuses focalisées
B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
H04N 1/409 - Amélioration des contours ou des détailsSuppression du bruit ou des erreurs
B29C 64/393 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
71.
METHOD FOR ASCERTAINING THE CHARGE STATE OF A PHASE-CHANGE MATERIAL
AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH (Autriche)
Inventeur(s)
Pernsteiner, Dominik
Schirrer, Alexander
Hofmann, René
Jakubek, Stefan
Abrégé
M, kM, kM, kM, kkorrM, kM, kM, kkM, kM, k, from which the charge state SOC is ascertained, for the at least one phase-change memory cell (2) at the time interval k.
G06F 30/28 - Optimisation, vérification ou simulation de l’objet conçu utilisant la dynamique des fluides, p. ex. les équations de Navier-Stokes ou la dynamique des fluides numérique [DFN]
F25D 11/00 - Dispositifs autonomes déplaçables associés à des machines frigorifiques, p. ex. réfrigérateurs ménagers
F28D 20/02 - Appareils ou ensembles fonctionnels d'accumulation de chaleur en généralAppareils échangeurs de chaleur de régénération non couverts par les groupes ou utilisant la chaleur latente
G06F 119/06 - Analyse de puissance ou optimisation de puissance
G06F 119/08 - Analyse thermique ou optimisation thermique
G06F 119/22 - Analyse de rendement ou optimisation de rendement
LUDWIG BOLTZMANN GESELLSCHAFT - ÖSTERREICHISCHE VEREINIGUNG ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG (Autriche)
Inventeur(s)
Baudis, Stefan
Bergmeister, Helga
Ehrmann, Katharina
Grasl, Christian
Liska, Robert
Podesser, Bruno
Schima, Heinrich
Abrégé
1212122 comprises one or more ester moieties; and a, b and c each independently represents an integer from 0 to 10 and n is a number ≥ 3 that represents the number of blocks in the polyadduct; with the proviso that, in each case within the same block, a + c ≥ 1 and, in all blocks together, at least one a ≥ 1 and at least one c ≥ 1.
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
The invention relates to a method for a reversible thermochemical storage and release of energy, wherein orthoboric acid is converted into boroxide, metaboric acid, or boroxide and metaboric acid by means of a water splitting process in order to store energy, and boroxide, metaboric acid, or boroxide and metaboric acid are converted into orthoboric acid by reacting with water in order to release energy. The reactions are carried out in a suspension medium, wherein orthoboric acid is provided in a suspended manner in the suspension medium in order to reversibly store energy of boric acid, and an energy source is used to bring the suspension medium with boric acid to a temperature at which the water splitting process is carried out; and boroxide and/or metaboric acid is provided in a suspended manner in the suspension medium for a reversible thermochemical release of energy. The suspension medium with boroxide and/or metaboric acid is reacted with water so that the reaction into orthoboric acid is carried out, and the heat resulting in the process is discharged to a heat load.
Method and apparatus to produce a wideband RF signal covering an increased first bandwidth, utilizing at least one narrowband transceiver (1) capable of producing an output RF signal with a base frequency fbase and a second bandwidth, wherein the second bandwidth is lower than the first bandwidth, and wherein the base frequency Case depends on the setting of at least one frequency register (2, 2′, 2″), which is adjustable by a control unit, as well as method to estimate the position of a narrowband RF transceiver (1) using a multitude of coherent wideband RF receivers (12) and computer-readable medium comprising computer-executable instructions causing an electronic device to perform the method.
The invention relates to a method for determining at least one speed component of a fluid stream, in particular for laser Doppler anemometry, the method having at least the steps of: - providing at least a first part-beam (105A) and a second part-beam (105B); - directing the first part-beam (105A) along a first optical path (4A) and directing the second part-beam (105B) along a second optical path (4B) onto a superimposition region (5) within the fluid stream so that the first optical path (4A) and the second optical path (4B) intersect in the superimposition region (5); - detecting a Doppler-shifted first part-beam scattered light signal (109A), which was back-scattered by tracer particles (107) in the fluid stream in the superimposition region (5), at least partially following the first optical path (4A); - detecting a Doppler-shifted solid angle scattered light signal (116), which was scattered by the tracer particles (107) in the superimposition region (5) into a path (6) different at least from the first optical path (4A) and from the second optical path (4B). The invention also relates to a corresponding device (1).
G01P 5/26 - Mesure de la vitesse des fluides, p. ex. d'un courant atmosphériqueMesure de la vitesse de corps, p. ex. navires, aéronefs, par rapport à des fluides en mesurant l'influence directe du courant de fluide sur les propriétés d'une onde optique de détection
76.
METHOD FOR PRODUCING PRODUCTS BASED ON NON-WOODY BIOMASS AS RAW MATERIAL
The invention relates to a method for producing products based on non-woody biomass as raw material, characterised in that non-woody biomass which contains cellulose, hemicelluloses and lignin and is in the form of particles is subjected to an extraction treatment with an extractant which comprises one or more organic solvents in an organic aqueous mixture of the solvent or solvents with water, wherein the content of fatty acids in the particles is reduced by the extraction treatment of the particles with the solvent by at least 70%, measured as hexanal content in wt.% after accelerated ageing for 72 hours at 90°C, but the content of cellulose, hemicelluloses and lignin is substantially preserved in this extraction treatment.
Optical device (1) for controlling a light beam (2) comprising: - a beam shaping unit (3) for increasing the uniformity of the spatial intensity profile of the light beam (2); - a lens system (4); and - a focusing unit (5); wherein the lens system comprises a first lens (6) and a second lens (7), wherein each of the first lens (6) and the second lens (7) comprises a stepped optical surface (8) formed by active sections (9) and reset sections (10) alternating with each other, wherein the active sections (9) stepwise form a surface profile (11), which is aspheric, wherein the stepped optical surface (8) of the first lens (6) faces the stepped optical surface (8) of the second lens (7).
The present invention relates to a microfluidic device for determining the transepithelial electrical resistance (TEER) of a cell layer or a cell assembly and/or for determining the impedance of cells, a cell layer or a cell assembly, said device comprising at least one microchannel (1) comprising at least a lower (3) and an upper compartment (2) separated by at least one porous membrane (4) and optionally an inner compartment (12), the lower compartment (3) comprising a bottom wall (7) and side walls (8), the upper compartment (2) comprising an upper wall (6) and side walls (8), the bottom (7) and upper wall (6), the side walls (8) and the at least one porous membrane (4) defining compartment volumes, wherein at least one porous membrane (4) comprises on its surface at least
A method for demodulation including the following steps: exciting a vibrationally mounted, at least sectionally bar-shaped oscillating element for oscillating in the range of a resonance frequency of the oscillating element, wherein a temporally varying, in particular periodic, excitation signal is used for excitation, and wherein at least the temporal variation of the excitation signal is known or determined; detecting a modulated oscillation of the oscillating element by means of at least one sensor, wherein the sensor supplies a sensor measurement variable that varies versus time as a function of an amplitude and a phase of the modulated oscillation of the oscillating element. According to the present teaching, it is provided that the method includes the following step: generate a first comparison signal by amplitude modulating a known temporally varying, in particular periodic, demodulation signal by means of the temporally varying sensor measurement variable.
G01Q 20/04 - Sondes auto-détectrices, c.-à-d. dans lesquelles la sonde génère elle-même un signal représentatif de sa position, p. ex. jauge piézoélectrique
G01Q 60/38 - Sondes, leur fabrication ou leur instrumentation correspondante, p. ex. supports
H03D 3/02 - Démodulation d'oscillations modulées en angle en détectant la différence de phase entre deux signaux obtenus à partir du signal d'entrée
80.
Method and apparatus for determining optical properties of a sample material
A method for determining optical properties of a sample material includes: determining a first intensity of light in a first polarization state that was reflected by the sample material; determining a second intensity of the light in a second polarization state that was reflected by the sample material; forming the ratio between the first intensity and the second intensity, or vice versa. Further, an apparatus for determining optical properties of a sample material, comprising at least one detector device for determining a first intensity of light in a first polarization state that was reflected by the sample material and for determining a second intensity of the light in a second polarization state that was reflected by the sample material and at least one computing unit for forming the ratio of the first intensity and the second intensity, or vice versa.
C07C 29/153 - Préparation de composés comportant des groupes hydroxyle ou O-métal liés à un atome de carbone ne faisant pas partie d'un cycle aromatique à six chaînons par réduction exclusivement des oxydes de carbone avec de l'hydrogène ou des gaz contenant de l'hydrogène caractérisée par le catalyseur utilisé
82.
Method of producing a test body for diffusion tensor imaging
2, wherein a virtual model of the test body is created and the virtual model is fed to a structuring device which produces the test body by means of a 3D printing-based, in particular lithography-based, structuring process, the structuring process being designed as a multiphoton lithography process, in particular as a multiphoton absorption process, in which the structuring material containing a photosensitizer or photoinitiator is irradiated in a location-selective manner, wherein the radiation is successively focused on focal points lying within the structuring material, resulting in that in each case a volume element of the material located in the focal point is subjected to a change in state by means of a photochemical reaction as a result of multiphoton absorption.
B29C 64/129 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
G01R 33/563 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne de matériaux en mouvement, p. ex. angiographie à écoulement contrasté
G01R 33/58 - Étalonnage des systèmes d'imagerie, p. ex. utilisant des sondes d'essai
G03F 7/029 - Composés inorganiquesComposés d'oniumComposés organiques contenant des hétéro-atomes autres que l'oxygène, l'azote ou le soufre
Memristive logic gate circuit, comprising a first memristive device (1), representing a first input node A of the logic gate circuit, a second memristive device (2), representing a second input node B of the logic gate circuit, and a third memristive device (3), representing an output node F of the logic gate circuit, wherein the first memristive device (1) and the second memristive device (2) are connected in series between a positive supply voltage terminal Vx (7) and a negative supply voltage terminal –Vx (8), wherein a connection point (6) is formed between the first memristive device (1) and the second memristive device (2), and wherein the third memristive device (3) is provided between the connection point (6) and a Ground contact (9).
G11C 13/00 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage non couverts par les groupes , ou
H03K 19/21 - Circuits OU EXCLUSIF, c.-à-d. donnant un signal de sortie si un signal n'existe qu'à une seule entréeCircuits à COÏNCIDENCES, c.-à-d. ne donnant un signal de sortie que si tous les signaux d'entrée sont identiques
84.
METHOD FOR PRODUCING A COMPOSITION COMPRISING ARCHAEAL LIPIDS FROM A SULFOLOBUS CELL CULTURE
Summary The present invention discloses a method for producing a composition comprising archaeal lipids from a Sulfolobuscell culture, comprising (1) growing a Sulfolobuscell culture at a temperature of 75 to 85° C. and at a growth rate of 0.025 to 0.035 per hour and extracting the archaeal lipids from the archaeal culture so as to obtain a composition for use for oral retard therapy, or (2) growing a Sulfolobuscell culture at a temperature of 75 to 85° C. and at a growth rate of 0.005 to 0.015 per hour and extracting the archaeal lipids from the archaeal culture so as to obtain a composition for use for oral acutetherapy; and compositions obtainable by such method.
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
85.
APPARATUS FOR OPTICAL IMAGE RECOGNITION AND CLASSIFICATION
nnmnmnnmnmn are not identical, and the outputs of each subpixel (3) are connected to form M output lines (4), wherein each output line (4) sums the photodetector currents produced by the m-th subpixels (3) in all N pixels (2, 2', 2'') and delivers a detector current of Formel (I), to be used for recognizing and classifying the optical image.
G06F 30/327 - Synthèse logiqueSynthèse de comportement, p. ex. logique de correspondance, langage de description de matériel [HDL] à liste d’interconnections [Netlist], langage de haut niveau à langage de transfert entre registres [RTL] ou liste d’interconnections [Netlist]
G06F 30/367 - Vérification de la conception, p. ex. par simulation, programme de simulation avec emphase de circuit intégré [SPICE], méthodes directes ou de relaxation
G06F 30/398 - Vérification ou optimisation de la conception, p. ex. par vérification des règles de conception [DRC], vérification de correspondance entre géométrie et schéma [LVS] ou par les méthodes à éléments finis [MEF]
87.
METHOD FOR DETECTING AND QUANTIFYING ANALYTES IN A MICROFLUIDIC DEVICE
Microfluidic device (1) comprising at least one fluid channel (2) comprising at least one inlet (3), wherein said at least one fluid channel (2) is fluidly connected to a first sensor (4) downstream of said at least one fluid inlet (3), wherein the first sensor (4) comprises at least one sensor cathode (5) and at least one sensor anode (6) formed on an essentially electrically isolating substrate (7), wherein the sensor cathode (5) and the sensor anode (6) are spaced apart by a gap (8) formed on the electrically isolating substrate (7), and wherein at least one analyte capturing molecule (9) is immobilized in the gap (8) on the substrate (7), wherein the at least one capturing molecule (9) is adapted to capture at least one analyte (10) of a fluid sample introduced into the inlet (3) and transported to the first sensor (4).
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
H01M 8/16 - Éléments à combustible biochimique, c.-à-d. éléments dans lesquels des micro-organismes agissent comme catalyseurs
The invention relates to a tunnel lining segment of reinforced concrete, wherein the tunnel lining segment has a load transfer area for a longitudinal joint, with at least one steel bar with an end face being installed in the tunnel lining segment, the steel bar being arranged in the tunnel lining segment in such a way that a tangent to a centroidal axis of the steel bar encloses an angle of between 0° and 45° in the end face with a normal to the load transfer area, and wherein the end face is arranged at a distance (a) from the load transfer area which is between 0 mm and 50 mm, preferably between 0 mm and 10 mm.
1212122 comprises one or more ester moieties; and a, b and c each independently represent an integer from 0 to 10 and n is a number ≥ 3 that represents the number of blocks in the polyadduct; with the proviso that, in each case within the same block, a + c ≥ 1 and, in all blocks together, at least one a ≥ 1 and at least one c ≥ 1.
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
LATTICE STRUCTURE, METHOD FOR STRETCHING OUT A LATTICE STRUCTURE, AND COMPUTER-IMPLEMENTED METHOD FOR CREATING A LATTICE MODEL OF THE LATTICE STRUCTURE
Lattice structure (1) for forming a three-dimensional structure, comprising border elements (2, 2') which span a surface, and lattice elements (3, 3') which are arranged between the border elements (2, 2') with the formation of crossing points (4), wherein the border elements (2, 2') and the lattice elements (3, 3') are rectilinear, elastic and have high tensile and compressive strength, wherein the lattice elements (3, 3') are fastened to the border elements (2, 2') in such a way that the lattice structure (1) can be brought from a planar position, in which it forms a planar surface section PO, into a stretched-out position, in which it forms a free-form surface section P1 approximating the structure, wherein the lattice elements (3, 3') follow geodetic lines between the border elements (2, 2') in both positions, and method for determining lattice elements (3, 3') of such a lattice structure (1).
The invention relates to a tool holder (3) for the detachable connection to a two-jaw gripper (2) on a robot arm, in particular a collaboration-capable robot device (1) for the human-machine interaction, comprising: a base body (4), a recess (5) for receiving the two-jaw gripper (2) on the robot arm, a receiving opening (6) for receiving a tool (7), in particular a rod-shaped tool, for example a battery-driven screwdriver.
122 is selected from divalent residues of unbranched, branched or cyclic aliphatic hydrocarbons with 3 to 15 carbon atoms, with the proviso that the salt of the formula (I) is water-soluble and is selected from compounds (1) to (28); and to the polyimides prepared from these salts by polycondensation.
A rotary current machine system and method for controlling an electric rotary current machine, in particular an induction machine, having a rotor, a stator and at least two phase windings is disclosed. At least one electrical signal, in particular a voltage signal, is applied to at least one phase winding, preferably all phase windings, of the rotary current machine, and the current waveform in the at least one phase winding is measured. An intermodulation signal component, induced in the rotary current machine by slotting effects and magnetic saturation effects, which is determined from the current waveform measured in the at least one phase winding, is used for controlling the rotary current machine.
H02P 21/09 - Calcul de l’angle de phase du champ basé sur l’équation de la tension de rotor en additionnant la fréquence de glissement et une fréquence proportionnelle à la vitesse
The invention relates to a method for preparing a tensile test on an elongate, more particularly fibrous, specimen (2), for example on a collagen fibril, comprising the steps of: - providing the elongate specimen (2); - attaching a handling particle (18) to the elongate specimen (2); - providing a force sensor (3), on which a retainer (13) for the handling particle (18) on the elongate specimen (2) is disposed; - connecting a handling apparatus (19) to the handling particle (18) on the elongate specimen (2); and - connecting the handling particle (18) on the elongate specimen (2) to the retainer (13) on the force sensor (3) by means of the handling apparatus (19). The invention also relates to a method and a device for performing a tensile test on an elongate specimen (2).
G01N 3/08 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression
95.
METHODS, APPARATUS AND KITS FOR BACTERIAL CELL LYSIS
The invention relates to a method for lysing a bacterial cell comprising the steps of: providing a sample comprising the bacterial cell, and adding a lysis agent to create a lysis reaction mixture; wherein the lysis agent comprises a water-miscible ionic liquid containing the 1-Ethyl-3-methylimidazolium cation ([C2mim]). The invention further provides an apparatus for carrying out the method as well as a kit for nucleic acid amplification from a bacterial cell and a kit for nucleic acid isolation from a bacterial cell.
The invention relates to a method for lysing a bacterial cell comprising the steps of: providing a sample comprising the bacterial cell, and adding a lysis agent to create a lysis reaction mixture; wherein the lysis agent comprises a water-miscible ionic liquid containing choline. The invention further provides an apparatus for carrying out the method as well as a kit for nucleic acid amplification from a bacterial cell and a kit for nucleic acid isolation from a bacterial cell.
G01N 3/08 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression
G01N 3/24 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant des efforts permanents de cisaillement
The present invention relates to a microfluidic device (1), preferably for producing a three-dimensional cell culture, having at least one chamber (2), and a fluid channel (3) which flows through at least part of the chamber (2) in order to provide a fluid stream which flows through the chamber (2) preferably continuously, wherein the chamber (2) is connected to a loading opening (4) and via the loading opening (4) can be loaded with hydrogel up to a desired fill level, characterised in that the chamber (2) comprises a main chamber (5) and a secondary chamber (6) connected to the main chamber (5), wherein, when the chamber (2) is being loaded with hydrogel up to the desired fill level, the secondary chamber is at least partially filled with hydrogel backed up from the main chamber (5).
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12M 1/32 - Inoculateur ou échantillonneur du type à champs multiples ou en continu
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 33/483 - Analyse physique de matériau biologique
The present invention relates to a microfluidic device (1) for cultivating cells, in particular for generating brain organoids, comprising at least two fluid channels (2) positioned essentially opposite to each other and a main chamber (3) located between the fluid channels (2), wherein the main chamber (3) comprises at least one preferably sealable access opening, and each of the at least two fluid channels (2) is fluidly connected to the main chamber (3) at at least one point of contact (4), wherein a slotted structure (5) is provided at each point of contact (4) separating the main chamber (3) from the respective fluid channel (2), wherein the slotted structure (5) is permeable to a liquid.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
G01N 33/483 - Analyse physique de matériau biologique
C12N 1/04 - Conservation des micro-organismes à l'état viable
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
The invention relates to a device for connecting a cannula to a container under reduced pressure, in particular a blood culture flask, comprising an inflow opening (2') for connecting to the cannula or to a connection tube connected to the cannula, an outflow opening (4') for connecting to a hollow pin for piercing a closure of the container, and a tight fluidic connection of the inflow opening (2') to the outflow opening (4'). According to the invention, a reservoir (9) which is separated from the fluidic connection and contains a specified gas quantity is connected to the fluidic connection with the interposition of a valve (6) which is preferably open towards the fluidic connection.
A61B 5/15 - Dispositifs de prélèvement d'échantillons de sang
A61B 5/154 - Dispositifs de prélèvement d'échantillons de sang spécialement adaptés pour le prélèvement d'échantillons de sang veineux ou artériel, p. ex. par des seringues utilisant des moyens préalablement mis sous vide
A61B 5/155 - Dispositifs de prélèvement d'échantillons de sang spécialement adaptés pour des prélèvements continus ou intermittents, p. ex. à intervalles prédéterminés