One of the purposes of the present invention is to provide a hemodialysis agent A having excellent storage stability. The solid hemodialysis agent A contains coated particles having a coating layer containing calcium chloride, and contains at least magnesium chloride as core particles of the coated particles.
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
One purpose of the present invention is to provide an agent A that is for hemodialysis and that has excellent storage stability. This solid agent A for hemodialysis includes a granulated material containing a first sodium chloride, magnesium chloride, and calcium chloride. In the granulated material, the amount of the magnesium chloride calculated as an anhydride is 5-80 parts by weight and the amount of the calcium chloride as calculated as an anhydride is 15-200 parts by weight, per 100 parts by weight of the first sodium chloride.
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
The present invention addresses the problem of providing a plasma spraying material with which it is possible to form an HAp film that has high hardness and is not susceptible to abrasion, even under conditions involving plasma spraying with low flame energy. In the present invention, an HAp powder having an average particle diameter (D50) of 15-40 μm and a pore volume of 0.01-0.30 cc/g at a pore diameter of 2000 nm or less as measured through mercury intrusion makes it possible to form an HAp film that has high hardness, is not susceptible to abrasion, and can be subjected to plasma spraying, even under conditions involving plasma spraying with low flame energy.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
C23C 4/04 - Revêtement par pulvérisation du matériau de revêtement à l'état fondu, p.ex. par pulvérisation à l'aide d'une flamme, d'un plasma ou d'une décharge électrique caractérisé par le matériau de revêtement
An object of the present invention is to provide a calcium phosphate powder that enables the preparation of a slurry for additive manufacturing with excellent dispersion stability, and enables the production of a three-dimensional additive manufacturing article with high strength, in additive manufacturing. Provided is a calcium phosphate powder, having an average particle size (D50) of 0.1 to 5.0 μm, and having a pore volume of mesopores (pore size: 2 to 50 nm) of 0.01 to 0.06 cc/g as measured by a gas adsorption method. The calcium phosphate powder has excellent dispersion stability in a slurry for additive manufacturing, and, by performing additive manufacturing using a slurry for additive manufacturing containing the calcium phosphate, it is possible to produce a three-dimensional additive manufacturing article with high strength, which is useful as an implant, such as an artificial bone.
C09D 4/06 - Compositions de revêtement, p.ex. peintures, vernis ou vernis-laques, à base de composés non macromoléculaires organiques ayant au moins une liaison non saturée carbone-carbone polymérisable en combinaison avec un composé macromoléculaire autre qu'un polymère non saturé des groupes
C09D 133/04 - Homopolymères ou copolymères d'esters
A61L 27/12 - Matériaux contenant du phosphore, p.ex. apatite
The purpose of the present invention is to provide a granulated material for a hemodialysis agent that contains an acetic acid salt and magnesium chloride and/or calcium chloride and has excellent storage stability. A granulated material to be used in a hemodialysis agent, said granulated material comprising a core particle and a coating formed on at least a part of the surface of the core particle, wherein the core particle contains an acetic acid salt and is substantially free of sodium chloride, and the coating contains magnesium chloride and/or calcium chloride.
A61K 31/7004 - Monosaccharides ayant uniquement des atomes de carbone, d'hydrogène et d'oxygène
A61K 33/14 - Chlorures des métaux alcalins; Chlorures des métaux alcalino-terreux
A61K 47/12 - Acides carboxyliques; Leurs sels ou anhydrides
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
5050) of 15-40 μm and a pore volume of 0.01-0.30 cc/g at a pore diameter of 2000 nm or less as measured through mercury intrusion makes it possible to form an HAp film that has high hardness, is not susceptible to abrasion, and can be subjected to plasma spraying, even under conditions involving plasma spraying with low flame energy.
C23C 4/04 - Revêtement par pulvérisation du matériau de revêtement à l'état fondu, p.ex. par pulvérisation à l'aide d'une flamme, d'un plasma ou d'une décharge électrique caractérisé par le matériau de revêtement
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/32 - Matériaux contenant du phosphore, p.ex. apatite
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
5050) is 0.1-5.0 μm, and the pore volume of mesopores (pore diameter of 2-50 nm) as measured by a gas adsorption method is 0.01-0.06 cc/g. Said calcium phosphate powder has excellent dispersion stability in an additive manufacturing slurry. A three-dimensional additively manufactured article that has high strength and is useful as an implant such as an artificial bone can be produced by performing additive manufacturing using an additive manufacturing slurry containing the calcium phosphate.
Provided are an aluminum phosphate compound exhibiting an excellent ability to purify, a method for producing the same, a carrier for purifying protein, and a method for purifying protein which uses the same. This aluminum phosphate compound exhibits a pore mode diameter in the range of 100-300nm, said pore mode diameter corresponding to the peaks appearing when the pore diameter (D) is in the range of 2,000nm or less in a Log differential pore volume distribution (dV/dlogD) obtained by the mercury press-in method.
B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
The purpose of the present invention is to provide a plasma spray material which is capable of forming a hydroxyapatite film that exhibits high adhesion strength with respect to substrates such as metal substrates. When used as a plasma spray material, hydroxyapatite powder having a modal diameter of 550-1000 nm in a pore diameter of at most 5000 nm as measured by a mercury intrusion method is capable of forming a hydroxyapatite film that exhibits high adhesion strength with respect to substrates such as metal substrates.
C01B 25/32 - Phosphates de magnésium, de calcium, de strontium ou de baryum
C23C 4/04 - Revêtement par pulvérisation du matériau de revêtement à l'état fondu, p.ex. par pulvérisation à l'aide d'une flamme, d'un plasma ou d'une décharge électrique caractérisé par le matériau de revêtement
10.
Anhydrous dibasic calcium phosphate, and method for producing same
An object of the present invention is to provide anhydrous dibasic calcium phosphate having good powder flowability and good dispersibility in water. An anhydrous dibasic calcium phosphate powder containing agglomerated particles formed by agglomerating anhydrous dibasic calcium phosphate particles having a modal pore diameter/mean particle diameter ratio of 0.2 to 0.34 exhibits good powder flowability and good dispersibility in water.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Industrial chemicals; chemicals for use in the manufacture
of cosmetics, dietary supplements for human, nutritional
supplements, and pharmaceuticals; chemical additives for use
in the manufacture of pharmaceuticals; chemical additives
for use in the manufacture of cosmetics; chemical additives
for use in the manufacture of food; chemical additives for
use in the manufacture of nutritional supplements;
non-metallic minerals other than for building or
construction. Pharmaceutical preparations; dental materials.
[Problem] To provide a method for producing a high-purity magnesium salt steadily at low cost. [Solution] A method for producing a high-purity magnesium salt, characterized in that a reaction step for the reaction of an insoluble magnesium compound-based raw material with hydrogen chloride is included, wherein the reaction step includes reacting hydrogen chloride in an amount of 2n mol (wherein n satisfies the formula: 0.00 < n ≤ 0.98) relative to 1 mol of Mg2+ ions contained in the raw material to produce a reaction product.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Industrial chemicals; chemicals for use in the manufacture of cosmetics, dietary supplements for human, nutritional supplements, and pharmaceuticals; chemical additives for use in the manufacture of pharmaceuticals; chemical additives for use in the manufacture of cosmetics; chemical additives for use in the manufacture of food; chemical additives for use in the manufacture of nutritional supplements; non-metallic minerals, namely, magnesite, dolomite, china clay, diatomaceous earth, talc, and sulphur, other than for building or construction Pharmaceutical preparations, namely, pharmaceutical solutions used in dialysis and pharmaceutical preparations used in dialysis; dental composite materials
The purpose of the present invention is to provide a plasma spray material which is capable of forming a hydroxyapatite film that exhibits high adhesion strength with respect to substrates such as metal substrates. When used as a plasma spray material, hydroxyapatite powder having a modal diameter of 550-1000 nm in a pore diameter of at most 5000 nm as measured by a mercury intrusion method is capable of forming a hydroxyapatite film that exhibits high adhesion strength with respect to substrates such as metal substrates.
C23C 4/04 - Revêtement par pulvérisation du matériau de revêtement à l'état fondu, p.ex. par pulvérisation à l'aide d'une flamme, d'un plasma ou d'une décharge électrique caractérisé par le matériau de revêtement
The purpose of the present invention is to provide novel nucleic acids having antitumor activity. Oligonucleotides comprising base sequences represented by SEQ ID NO: 1-6 exhibit a growth inhibitory action against cancer cells but do not affect normal cells, and thus are useful as anticancer agents.
C12N 15/11 - Fragments d'ADN ou d'ARN; Leurs formes modifiées
A61K 31/711 - Acides désoxyribonucléiques naturels, c. à d. contenant uniquement des 2'-désoxyriboses liés à l'adénine, la guanine, la cytosine ou la thymine et ayant des liaisons 3'-5' phosphodiester
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Industrial chemicals; glue and adhesives for industrial
purposes; plant growth regulation preparations; fertilizers;
artificial sweeteners; unprocessed plastics; lactose for
industrial purposes; chemicals for use in the manufacture of
cosmetics, dietary supplements for humans, nutritional
supplements, and pharmaceuticals. Pharmaceutical preparations; oiled paper for medical
purposes; drug delivery agents in the form of edible wafers
for wrapping powdered pharmaceuticals; gauze for medical
use; capsules for medicines; eyepatches for medical
purposes; ear bandages; menstruation bandages; menstruation
tampons; sanitary napkins; sanitary panties; absorbent
cotton; adhesive plasters; bandages for dressings; liquid
bandages; breast-nursing pads; dental materials; lactose for
medical purposes; lacteal flour for babies.
17.
ANHYDROUS DIBASIC CALCIUM PHOSPHATE, AND METHOD FOR PRODUCING SAME
The purpose of the present invention is to provide anhydrous dibasic calcium phosphate having good powder fluidability and good dispersibility in water. An anhydrous dibasic calcium phosphate powder containing agglomerated particles that are produced by agglomerating anhydrous dibasic calcium phosphate particles having a (modal pore diameter)/(average particle diameter) ratio of 0.2 to 0.34 has good powder fluidability and good dispersibility in water.
An object of the present invention is to provide a polyolefin composition prepared by kneading a hygroscopic inorganic filler into a polyolefin, without substantially using an additive such as a dispersant or an antioxidant, the polyolefin composition having good dispersibility of the hygroscopic inorganic filler as well as excellent moldability. By kneading anhydrous magnesium sulfate as a hygroscopic inorganic filler into a polyolefin, without substantially adding an additive such as a dispersant or an antioxidant, and by setting the moisture content in the kneaded product to 0.1 wt % or less, a polyolefin composition having good dispersibility of anhydrous magnesium sulfate as well as excellent moldability can be obtained.
B32B 27/20 - Produits stratifiés composés essentiellement de résine synthétique caractérisée par l'emploi d'additifs particuliers utilisant des charges, des pigments, des agents thixotropiques
B65D 81/26 - Adaptations pour empêcher la détérioration ou l'altération du contenu; Applications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux avec dispositifs pour évacuer ou absorber les fluides, p.ex. s'écoulant du contenu; Emploi de produits empêchant la corrosion ou de dessiccateurs
C08J 3/20 - Formation de mélanges de polymères avec des additifs, p.ex. coloration
Provided is a powder containing ferric pyrophosphate that affords high iron absorbability, as a main component of an oral iron preparation. The present invention relates to a composite powder containing ferric pyrophosphate, which is a powder containing ferric pyrophosphate and a sodium component, wherein (1) the content of ferric pyrophosphate is 95 wt % or higher, and (2) a (Fe+Na)/P molar ratio is 0.8 to 1.0.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Industrial chemicals; glue and adhesives for industrial purposes; plant growth regulation preparations; fertilizers; artificial sweeteners; unprocessed plastics; lactose for industrial purposes; chemicals for use in the manufacture of cosmetics, dietary supplements for humans, nutritional supplements, and pharmaceuticals Pharmaceutical solutions used in dialysis; pharmaceutical preparations used in dialysis; oiled paper for medical purposes; drug delivery agents in the form of edible wafers for wrapping powdered pharmaceuticals; gauze for dressings; capsules sold empty for pharmaceuticals; eyepatches for medical purposes; ear bandages; menstruation bandages; menstruation tampons; sanitary napkins; sanitary panties; absorbent cotton, namely, cotton for medical purposes, cotton sticks for medical purposes, and antiseptic cotton; adhesive plasters for medical purposes; bandages for dressings; antiseptic liquid bandages; breast-nursing pads; materials for dental fillings and for sealing purposes; lactose for medical purposes; lacteal flour for babies
21.
Dialysis agent a containing acetic acid and acetate salt, and a two-part dialysis agent using thereof
A dialysis agent A including a mixture containing glucose, acetic acid, and acetate salt, but not sodium bicarbonate, wherein the molar ratio of acetic acid:acetate salt is 1:0.5 to 1:2, and wherein a total amount of the acetic acid and acetate salt contained in the dialysis agent A is between 2 mEq/L and 6 mEq/L when the dialysis agent A is dissolved in 1 L of a bicarbonate dialysate.
Provided is a powder composition containing an oily substance, the powder composition having good oxidation stability and excellent compression moldability. The powder composition containing an oily substance contains a powdery calcium silicate-based material, and an oily substance impregnated into the material. In the material, a cumulative pore volume for a pore size of 10 to 70 nm is 1.1 cc/g or more, and a cumulative pore volume for a pore size of 70 to 500 nm is 2.0 cc/g or less.
A61K 31/202 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique ayant au moins trois doubles liaisons, p.ex. acide linolénique
The purpose of the present invention is to provide an acetate compound in which acetic acid odor can be reduced and decomposition of glucose can be suppressed even when the acetate compound is made to coexist with glucose. This compound is a higher-order acetate compound containing acetic acid-sodium acetate mixed crystals, wherein a diffraction peak A at 2θ=8.8°±0.2° and a diffraction peak B at 2θ=22.3°±0.2° are observed in a powder X-ray diffraction measurement, and the ratio Ia/Ib of the integrated intensity Ia of the diffraction peak A to the integrated intensity Ib of the diffraction peak B is less than 1.447. By using the higher-order acetate compound, volatilization of acetic acid can be effectively suppressed, acetic acid odor can be reduced, and decomposition of glucose can be suppressed even when the acetate compound is made to coexist with glucose.
A61K 47/12 - Acides carboxyliques; Leurs sels ou anhydrides
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
C07C 51/43 - Séparation; Purification; Stabilisation; Emploi d'additifs par changement de l'état physique, p.ex. par cristallisation
The present invention addresses the problem of providing a hemodialysis solid agent A, in which acetic acid odor can be reduced, in which solidification due to storage, decomposition of glucose when made to coexist with glucose, and an increase in pH when dissolved in water can be suppressed, and which has excellent storage stability. The problem can be solved by a hemodialysis solid agent A which substantially contains only one among magnesium chloride and potassium chloride, and which includes a first fraction composed of granules containing calcium chloride and a second fraction containing acetic acid and acetate.
A61K 47/12 - Acides carboxyliques; Leurs sels ou anhydrides
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
25.
Powdered tobermorite-type calcium silicate-based material and method for producing same
2/CaO in the material is 1.5 or more, and (2) a cumulative pore volume having a pore size of 3.6 nm to 200 nm in the material is 0.9 cc/g or more, and a cumulative pore volume having a pore size of 3.6 nm to 5000 nm is 2.6 cc/g or more.
B01J 20/10 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant de la silice ou un silicate
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
A61K 8/02 - Cosmétiques ou préparations similaires pour la toilette caractérisés par une forme physique particulière
[Problem] To provide a powder composition containing an oily substance and having a high oxidation stability and an excellent compression moldability. [Solution] A powder composition containing an oily substance, which comprises a powdery calcium silicate-based material and the oily substance impregnated in the material, characterized in that, in the aforesaid material, the cumulative volume of pores with pore diameter of 10-70 nm is 1.1 cc/g or more and the cumulative volume of pores with pore diameter of 70-500 nm is 2.0 cc/g or less.
A61K 31/202 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique ayant au moins trois doubles liaisons, p.ex. acide linolénique
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p.ex. poudres
[Problem] To provide a powder composition containing an oily substance and having a high oxidation stability and an excellent compression moldability. [Solution] A powder composition containing an oily substance, which comprises a powdery calcium silicate-based material and the oily substance impregnated in the material, characterized in that, in the aforesaid material, the cumulative volume of pores with pore diameter of 10-70 nm is 1.1 cc/g or more and the cumulative volume of pores with pore diameter of 70-500 nm is 2.0 cc/g or less.
A61K 31/202 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique ayant au moins trois doubles liaisons, p.ex. acide linolénique
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p.ex. poudres
[Problem] To provide a powder containing ferric pyrophosphate with which it is possible to obtain high iron absorbability, the powder being provided as a main ingredient of an oral iron formulation. [Solution] A powder containing ferric pyrophosphate and a sodium component, wherein the ferric-pyrophosphate-containing composite powder is characterized in that (1) the ferric pyrophosphate content is 95 wt% or higher, and (2) the (Fe + Na)/P molar ratio is 0.8-1.0.
A solid dialysis A agent is provided, which is to be used in preparing a bicarbonate dialysis fluid, wherein: the solid dialysis A agent contains glucose, acetic acid and an acetate salt; at least a part of a mixture of the acetic acid with the acetate salt is an alkali metal diacetate; and the acetic acid/acetate salt molar ratio is adjusted to 1/0.5 to 1/2. This solid dialysis A agent makes it possible to prepare a bicarbonate dialysis fluid which has a total acetate ion concentration of 2 to less than 6 mEq/L. Further, the dialysis A agent exhibits excellent stability of ingredients and a reduced acetic acid odor.
A61K 33/14 - Chlorures des métaux alcalins; Chlorures des métaux alcalino-terreux
A61K 47/12 - Acides carboxyliques; Leurs sels ou anhydrides
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
A61K 33/00 - Préparations médicinales contenant des ingrédients actifs inorganiques
30.
PACKAGED SODIUM CHLORIDE AND STORAGE METHOD FOR SODIUM CHLORIDE
The purpose of the present invention is to provide a storage technology for sodium chloride having excellent property stability, with which it is possible to inhibit the solidification of sodium chloride, even during long-term storage, without adding additives. By setting the purity of sodium chloride to at least 99.5 wt% and the average particle diameter to at least 150 μm, storing the sodium chloride in a moisture-proof container having a moisture permeability of less than 3 g/m2∙24h, and setting the relative humidity inside the moisture-proof container so as to be maintained at 55% or less, it is possible to prevent the sodium chloride from solidifying even during long-term storage and to increase the property stability of the sodium chloride.
B65D 81/24 - Adaptations pour empêcher la détérioration ou l'altération du contenu; Applications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux
The purpose of the present invention is to provide a polyolefin composition obtained by kneading a hygroscopic inorganic filler into a polyolefin essentially without using an additive such as a dispersant or an antioxidant, said polyolefin composition having excellent moldability and good dispersibility of the hygroscopic inorganic filler. A polyolefin composition having excellent moldability and good dispersibility of anhydrous magnesium sulfate can be obtained by kneading anhydrous magnesium sulfate, which serves as a hygroscopic inorganic filler, into a polyolefin essentially without admixing an additive such as a dispersant or an antioxidant, and by setting the moisture content of the mixture to 0.1 wt% or less.
C08L 23/00 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carbone; Compositions contenant des dérivés de tels polymères
B32B 9/00 - Produits stratifiés composés essentiellement d'une substance particulière non couverte par les groupes
B32B 27/32 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyoléfines
B65D 65/40 - Emploi de stratifiés pour des buts particuliers d'emballage
C08J 3/20 - Formation de mélanges de polymères avec des additifs, p.ex. coloration
C08K 3/30 - Composés contenant du soufre, du sélénium ou du tellure
32.
POWDERED TOBERMORITE-TYPE CALCIUM SILICATE-BASED MATERIAL AND METHOD FOR PRODUCING SAME
[Problem] To provide a powdered tobermorite type calcium silicate-based material that can exhibit high oil absorption. [Solution] A powdered tobermorite type calcium silicate-based material characterized in that (1) a SiO2/CaO molar ratio is 1.5 or more, and (2) a cumulative volume of pores of pore sizes of 3.6 to 200 nm is 0.9 cc/g or more and a cumulative volume of pores of pore sizes of 3.6 to 5000 nm is 2.6 cc/g or more.
B01D 53/14 - SÉPARATION Épuration chimique ou biologique des gaz résiduaires, p.ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par absorption
33.
POWDERED TOBERMORITE TYPE CALCIUM SILICATE-BASED MATERIAL AND METHOD FOR PRODUCING SAME
[Problem] To provide a powdered tobermorite type calcium silicate-based material that can exhibit high oil absorption. [Solution] A powdered tobermorite type calcium silicate-based material characterized in that (1) a SiO2/CaO molar ratio is 1.5 or more, and (2) a cumulative volume of pores of pore sizes of 3.6 to 200 nm is 0.9 cc/g or more and a cumulative volume of pores of pore sizes of 3.6 to 5000 nm is 2.6 cc/g or more.
B01D 53/14 - SÉPARATION Épuration chimique ou biologique des gaz résiduaires, p.ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par absorption
34.
POWDERED GYRO-LIGHT-TYPE CALCIUM SILICATE HAVING HIGH OIL ABSORBENCY AND LARGE PARTICLE DIAMETER, AND PRODUCTION METHOD THEREFOR
The purpose of the present invention is to provide a powdered gyro-light-type calcium silicate having a comparatively large particle diameter and also having high oil absorbency and high particle strength. This powdered gyro-light-type calcium silicate is characterized by: (1) having an oil absorbency of at least 2.8 mL/g; (2) having an average particle diameter of at least 40 µm; and (3) the change in the average particle diameter between before processing and after processing being no more than 15%, said processing being the insertion of the gyro-light-type calcium silicate to a laser diffraction particle size distribution meter such that the DV value becomes 0.1-0.6, and circulating same for 5 minutes at a flow rate of 32.5 mL/sec.
[Problem] To provide a solid dialysis A agent which is to be used in preparing a bicarbonate dialysis fluid, which enables the setting of a low total acetate ion content in a dialysis fluid, and which exhibits excellent storage stability of glucose or the like and a reduced acetic acid odor. [Solution] A solid dialysis A agent which is to be used in preparing a bicarbonate dialysis fluid, wherein: the solid dialysis A agent contains glucose, acetic acid and an acetate salt; at least a part of a mixture of the acetic acid with the acetate salt is an alkali metal diacetate; and the acetic acid/acetate salt molar ratio is adjusted to 1/0.5 to 1/2. This solid dialysis A agent makes it possible to prepare a bicarbonate dialysis fluid which has a total acetate ion concentration of 2 to less than 6 mEq/L. Further, the dialysis A agent exhibits excellent stability of ingredients and a reduced acetic acid odor.
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
36.
THREE-PACK TYPE DIALYSIS AGENT CONTAINING ACETIC ACID AND ACETIC ACID SALT
The purpose of the present invention is to provide a three-pack type dialysis agent with which it is possible to set the total acetic acid ion content in a dialysis fluid at a low value and which is excellent in terms of the storage stability of glucose, etc. and can be reduced in the odor of acetic acid. Therewith, it is possible to prepare a dialysis fluid so that the bicarbonate ion concentration can be changed at will according to need, while the concentrations of trace metal ions such as potassium ions, calcium ions, and magnesium ions are kept constant. The three-pack type dialysis agent comprises agent S comprising sodium chloride, agent B comprising sodium bicarbonate, and agent A containing glucose and an electrolyte ingredient which is neither sodium chloride nor sodium bicarbonate. By making the agent A contain acetic acid and an acetic acid salt and satisfy that the molar ratio of acetic acid/acetic acid salt is 1/(0.5-2), a bicarbonate dialysis fluid having a total acetic acid ion concentration of 2 mEq/L or higher but less than 6 mEq/L can be prepared. This agent A not only is excellent in terms of the stability of the ingredients including glucose but also can be reduced in the odor of acetic acid. According to the three-pack type dialysis agent, by controlling the amounts of the agents S, B, and A to be added when preparing a dialysis fluid, the bicarbonate ion concentration and/or sodium concentration in the dialysis fluid can be also changed.
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
37.
ORAL PHOSPHORUS-ADSORBING AGENT OF LOW CALCIUM ABSORPTION TYPE
The purpose of the present invention is to provide an oral phosphorus-adsorbing agent which can achieve the adsorption of phosphorus by calcium carbonate and/or calcium acetate in the body and can minimize the absorption of calcium resulting from the calcium carbonate and/or calcium acetate therein. In administrating calcium carbonate and/or calcium acetate as an oral phosphorus-adsorbing agent, use of alginic acid and/or an alginic acid salt except calcium alginate together with the phosphorus-adsorbing agent makes it possible to inhibit a living body from absorbing calcium while ensuring an effective phosphorus-adsorbing activity of calcium carbonate and/or calcium acetate.
A61K 9/48 - Préparations en capsules, p.ex. de gélatine, de chocolat
A61K 31/7012 - Composés ayant un groupe carboxyle libre ou estérifié, lié directement ou par une chaîne carbonée, à un atome de carbone du radical saccharide, p.ex. acide glucuronique, acide neuraminique
A61P 3/12 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase des électrolytes
38.
DIALYSIS A AGENT COMPRISING ACETIC ACID AND ACETATE, AND TWO-PART DIALYSIS AGENT USING SAME
The objective of the present invention is to provide: a dialysis A agent with which the total content of acetate ions in a dialysis fluid can be set to a low value and which has excellent preservation stability of glucose, is capable of reducing acetic acid odor and is capable of suppressing corrosion of a dialysis fluid preparation device and a dialysis device; and a two-part dialysis agent which uses the dialysis A agent. The dialysis A agent, which is used for the preparation of a bicarbonate dialysis fluid, comprises glucose, acetic acid and acetate and by satisfying 1:0.5-2 for the molar ratio of acetic acid:acetate, becomes capable of preparing the bicarbonate dialysis fluid such that the total acetate ion concentration is 2 mEq/L or more and less than 6 mEq/L. In addition, the dialysis A agent has excellent stability of glucose, is capable of reducing acetic acid odor and is capable of suppressing corrosion of a dialysis fluid preparation device and a dialysis device
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
39.
DIALYSIS AGENT A COMPRISING ACETIC ACID AND ACETATE SALT, AND TWO PACK TYPE DIALYSIS AGENT
The purpose of the present invention is to provide a dialysis agent A, which is able to set the total acetate ion content in the dialysate to a low value, excellent in storage stability of glucose, able to reduce the acetic acid odor, and able to suppress the corrosion of the dialysate delivery system and the dialysis machine, as well as to provide a two pack type dialysis agent utilizing the dialysis agent A. In the dialysis agent A used in the preparation of a bicarbonate dialysate, which is used as one part of a two pack type dialysis agent, it becomes possible to prepare a bicarbonate dialysate having the total acetate ion concentration of between 2 mEq/L or more and less than 6 mEq/L by allowing to include glucose, acetic acid and acetate salt and to satisfy the molar ratio of 1:0.5 to 2 of acetic acid and acetate salt, and include acetic acid and acetate salt in a total amount of between 2 mEq or more and less than 6 mEq in the dialysis agent A required to prepare IL of the bicarbonate dialysate. Moreover, according to the dialysis agent A, in addition to the excellent stability of glucose, it is possible to reduce the acetic acid odor, and furthermore possible to suppress the corrosion of the dialysate delivery system and the dialysis machine.
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/12 - Acides carboxyliques; Leurs sels ou anhydrides
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
40.
Dialysis agent a containing acetic acid and acetate salt, and a two-part dialysis agent using thereof
The purpose of the present invention is to provide a dialysis agent A, which is able to set the total acetate ion content in the dialysate to a low value, excellent in storage stability of glucose, able to reduce the acetic acid odor, and able to suppress the corrosion of the dialysate delivery system and the dialysis machine, as well as to provide a two pack type dialysis agent utilizing the dialysis agent A.
In the dialysis agent A used in the preparation of a bicarbonate dialysate, which is used as one part of a two pack type dialysis agent, it becomes possible to prepare a bicarbonate dialysate having the total acetate ion concentration of between 2 mEq/L or more and less than 6 mEq/L by allowing to include glucose, acetic acid and acetate salt and to satisfy the molar ratio of 1:0.5 to 2 of acetic acid and acetate salt, and include acetic acid and acetate salt in a total amount of between 2 mEq or more and less than 6 mEq in the dialysis agent A required to prepare 1 L of the bicarbonate dialysate. Moreover, according to the dialysis agent A, in addition to the excellent stability of glucose, it is possible to reduce the acetic acid odor, and furthermore possible to suppress the corrosion of the dialysate delivery system and the dialysis machine.
A61K 33/14 - Chlorures des métaux alcalins; Chlorures des métaux alcalino-terreux
41.
Preparation apparatus and preparation method for dialysis fluid of variable bicarbonate ion concentration type, dialysate of variable bicarbonate ion concentration type, and dialysis system of variable bicarbonate ion concentration type
Technology for preparing a dialysis fluid capable of flexibly changing bicarbonate ion concentration and maintaining concentrations of electrolytes such as potassium, calcium, and magnesium at constant levels during dialysis according to the disease state of a patient. A three-component dialysate containing an agent S containing sodium chloride, an agent B containing sodium bicarbonate, and an agent A containing electrolyte components other than sodium chloride and sodium bicarbonate, with suitable adjustment of the amount of the agent B during dialysis fluid preparation maintains concentrations of trace metal ions such as potassium ions, calcium ions, and magnesium ions in a dialysis fluid at constant levels and flexibly changes the bicarbonate ion concentration therein. Adjusting the ratio between the amount of the agent S and agent B when the dialysate is used also makes it possible to maintain the sodium ion concentration at a constant level or flexibly change the sodium ion concentration.
Provided is a method that enables a calcium silicate-based material to be produced more efficiently. The method of producing a calcium silicate-based material comprises: (1) a step of obtaining a reaction product by reacting raw materials containing a calcium component, a silicon component and an aluminum component in an aqueous medium; and (2) a step of forming calcium silicate by subjecting the reaction product to hydrothermal treatment.
PREPARATION APPARATUS AND PREPARATION METHOD FOR DIALYSIS FLUID OF VARIABLE BICARBONATE ION CONCENTRATION TYPE, DIALYSATE OF VARIABLE BICARBONATE ION CONCENTRATION TYPE, AND DIALYSIS SYSTEM OF VARIABLE BICARBONATE ION CONCENTRATION TYPE
An object of the present invention is to provide a technology for preparing a dialysis fluid that is capable of flexibly changing the bicarbonate ion concentration and maintaining the concentrations of electrolytes such as potassium, calcium, and magnesium at constant levels even during dialysis according to the disease state of a patient. In connection with a three-component dialysate containing an agent S containing sodium chloride, an agent B containing sodium bicarbonate, and an agent A containing electrolyte components other than sodium chloride and sodium bicarbonate, suitably adjusting the amount of the agent B during dialysis fluid preparation makes it possible to maintain the concentrations of trace metal ions such as potassium ions, calcium ions, and magnesium ions in a dialysis fluid at constant levels and flexibly change the bicarbonate ion concentration therein. Moreover, in the three-component dialysate, adjusting the ratio between the amount of the agent S and the amount of the agent B when the dialysate is used also makes it possible to maintain the sodium ion concentration at a constant level or flexibly change the sodium ion concentration.
A61K 33/14 - Chlorures des métaux alcalins; Chlorures des métaux alcalino-terreux
A61K 33/00 - Préparations médicinales contenant des ingrédients actifs inorganiques
A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
A61P 7/08 - Substitut de plasma; Solutions de perfusion; Dyalisats ou hémodyalisats; Médicaments pour le traitement des troubles électrolytiques ou acido-basiques, p.ex. choc hypovolémique
The present invention pertains to a bicarbonate dialysis agent that is free of acetic acid and citric acid, is safe, is easy to handle during production and during use, and has excellent safety during storage, concentrate preparation, and dialysate preparation; more specifically, the present invention pertains to a bicarbonate dialysis agent comprising: an A agent that includes gluconic acid and/or glucono-delta-lactone and gluconate but does not include acetic acid, citric acid, or sodium hydrogen carbonate; and a B agent that includes sodium hydrogen carbonate.
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
45.
Method for manufacturing calcium silicate based composition
Provided is a method that enables a calcium silicate-based material to be produced more efficiently. The method of producing a calcium silicate-based material comprises: (1) a step of obtaining a reaction product by reacting raw materials containing a calcium component, a silicon component and an aluminum component in an aqueous medium; and (2) a step of forming calcium silicate by subjecting the reaction product to hydrothermal treatment.
[Problem] To provide a magnesium sulfate desiccant which has excellent dispersibility and storage stability. [Solution] A magnesium sulfate desiccant containing a powder that is composed of coated particles each of which is obtained by forming a coating layer on the surface of a particle of magnesium sulfate represented by chemical formula of MgSO4·nH2O (wherein 0 ≤ n ≤ 3). The magnesium sulfate desiccant is characterized in that: (1) the coating layer contains at least one coating material that is a carboxylic acid or a salt thereof; (2) the powder has an average particle diameter of 5 μm or less; and (3) the contact angle of water with the surface that is formed of the powder is 20˚ or more. A method for producing the magnesium sulfate desiccant.
B01D 53/28 - Emploi de substances spécifiées comme agents desséchants
B01J 20/04 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant des composés des métaux alcalins, des métaux alcalino-terreux ou du magnésium
Provided is a water retention assistant that exhibits superior water retention while limiting marked reduction in absorption rate. The invention relates to a water retention assistant that is contained in absorbents for absorbing liquids, wherein the water retention assistant comprises polysaccharides (excluding cellulosic compounds) and cellulosic compounds.
C08L 1/00 - Compositions contenant de la cellulose, de la cellulose modifiée ou des dérivés de la cellulose
A61F 13/15 - Garnitures absorbantes, p.ex. serviettes ou tampons hygiéniques pour application externe ou interne au corps; Moyens pour les maintenir en place ou les fixer; Applicateurs de tampons
A61F 13/49 - Garnitures absorbantes, p.ex. serviettes ou tampons hygiéniques pour application externe ou interne au corps; Moyens pour les maintenir en place ou les fixer; Applicateurs de tampons caractérisées par la forme spécialement adaptées pour être portées autour de la taille, p.ex. couches-culottes
A61F 13/53 - Garnitures absorbantes, p.ex. serviettes ou tampons hygiéniques pour application externe ou interne au corps; Moyens pour les maintenir en place ou les fixer; Applicateurs de tampons caractérisées par le milieu absorbant
Provided is a particulate formulation which can exhibit excellent particle properties, etcetera, despite including a relatively large amount of active pharmaceutical components. The present invention is a particulate formulation formed from particles containing pharmaceutically acceptable inorganic material, and active pharmaceutical components, and is characterised in that: (1) the inorganic material has low water-solubility, and (2) the inclusion amount of the active pharmaceutical components is 50-95 weight%.
Provided is a nuclear particle which is for a pharmaceutical formulation and which is capable of emitting relatively large amounts of active pharmaceutical components at a specified timing. The present invention is a nuclear particle for forming a film, containing active pharmaceutical components, on a surface, and this decay-type nuclear particle for a pharmaceutical formulation is characterised in that: (1) the nuclear particle contains pharmaceutically acceptable inorganic material, and a decay promoting component; (2) the inorganic material has poor solubility in water; (3) the inclusion amount of the inorganic material is 50-95 weight%; and (4) the bulk density of the nuclear particle is at least 0.6g/mL.
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p.ex. carbomères
A61K 47/36 - Polysaccharides; Leurs dérivés, p.ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
[Problem] To provide a magnesium-silicate-containing regenerating agent for degraded edible oils, which has both good deoxidizing capability and good decoloring capability. [Solution] The present invention relates to a regenerating agent for degraded edible oils, which contains magnesium silicate and is characterized in that (1) the magnesium silicate is a crystal system of a tri-octahedral smectite clay mineral, (2) the magnesium silicate has a ratio of the integral intensity (Ib) at a peak appearing at 2θ = 26-28° to the integral intensity (Ia) at a peak appearing at 2θ = 18-20° (i.e., Ib/Ia) of 1-2 in an X-ray diffraction measurement, and (3) the magnesium silicate has a SiO2/MgO ratio (X) of 1.2-3.8 by mole.
Disclosed are a fructose absorption inhibitor that has a monoterpene as the active ingredient, and a preventative or therapeutic agent that is for symptoms or maladies caused by overconsumption of fructose; more specifically, disclosed are a preventative or therapeutic agent for hyperlipidemia, a triglyceride increase suppression agent, and a fructose absorption inhibitor containing a monoterpene.
A61K 31/201 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique ayant une ou deux doubles liaisons, p.ex. acides oléique ou linoléique
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p.ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/04 - Anorexigènes; Médicaments de l'obésité
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p.ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénal
A61P 9/14 - Vasoprotecteurs; Antihémorroïdaux; Médicaments pour le traitement des varices; Stabilisateurs capillaires
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
52.
DIALYSIS COMPOSITION, HEMODIALYSIS SYSTEM, AND HEMODIALYZER
Provided is a hemodialyzer capable of efficiently eliminating phosphorus in the blood without a phosphorus adsorbent being brought into direct contact with the blood circulating in an extracorporeal blood circuit for the purpose of dialysis treatment. Specifically disclosed is a hemodialyzer which is provided with a cylindrical casing and a hollow fiber dialysis membrane loaded along the length direction of the casing within the casing and in which the blood is passed through either the casing or the hollow fiber dialysis membrane, and a dialysis solution is passed through the other. Said hemodialyzer is characterized in that the phosphorus adsorbent is present in the casing or the hollow fiber dialysis membrane, through which the dialysis solution is passed.
Disclosed is a method for producing βTCP fine powder having higher purity than conventional products. The method for producing high purity βTCP fine powder comprises 1) a first step wherein a slurry containing tricalcium phosphate is produced by reacting phosphate ions and a calcium salt in water, 2) a second step in which a wet crushed material that contains fine powder for the solid content is prepared by wet crushing this slurry or a moist solid portion obtained therefrom and 3) a third step for obtaining the βTCP fine powder by baking the wet crushed material.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Calcium silicate; calcium silicate for use in the
manufacture of pharmaceuticals; chemicals; adhesives used in
industry; plant growth regulation preparations; fertilizers;
non-metallic minerals, namely gyrolite. Pharmaceutical preparations; oiled paper for medical
purposes; cachets for pharmaceutical purposes; gauze for
dressings; empty capsules for pharmaceuticals; eyepatches
for medical purposes; adhesive bandages for ears;
menstruation bandages; menstruation tampons; sanitary
napkins; sanitary panties; antiseptic cotton; adhesive
medical plasters; bandages for dressings; collodion for
pharmaceutical purposes; breast-nursing pads; dental
materials; bracelets for medical purposes.
Disclosed is an agent for regenerating a deteriorated cooking oil, which has a good deoxidizing capability and is effectively prevented from the elution of a calcium component therefrom. Specifically disclosed is an agent for regenerating a deteriorated cooking oil, which comprises calcium silicate. The agent is characterized in that (1) the above-mentioned calcium silicate has a SiO2/CaO ratio (R') of 1.0 to 6.0 by weight and (2) the above-mentioned calcium silicate has a water content of 12 wt% or less.
C11B 13/00 - Obtention de graisses, huiles ou acides gras à partir de résidus
A23D 9/02 - Autres huiles ou graisses comestibles, p.ex. huiles pour cuisson caractérisées par leur production ou leur traitement
B01J 20/10 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant de la silice ou un silicate
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Calcium silicate used as pharmaceutical additives; calcium silicate used as cosmetic additives; calcium silicate used as additives for stabilizing or improving deodorizer; calcium silicate used as gum or resin additives; calcium silicate used as nutritional food additives, none of the aforesaid goods being used for agricultural purposes
The present invention provides a core particle for a pharmaceutical preparation which features the requisite properties of a core particle, and which has enough chemical stability, and in which reactivity with the drug (an active pharmaceutical ingredient) is limited or prevented. More specifically, the present invention relates to a core particle wherein a film containing an active pharmaceutical ingredient can be formed on the surface thereof, and (1) the core particle comprises a pharmaceutically acceptable inorganic material, (2) the inorganic material is poorly soluble in water, and (3) pH of a solution of the inorganic material is 5 to 8.
Provided is a powder for molding with which the problems of nonuniformity, fluidity, and the like that are associated with the use of a mixed powder as a powder for molding are inhibited or prevented. The powder for molding comprises particles wherein one particle contains an inorganic component and a water-soluble organic polymer component. Also provided is a method for producing a molded object using the same powder.
ASAHI ORGANIC CHEMICALS INDUSTRY CO., LTD. (Japon)
Tomita Pharmaceutical Co., Ltd. (Japon)
Inventeur(s)
Matsumoto, Yasuhiro
Tomiyasu, Kei
Mukaijo, Mina
Oonishi, Syouichi
Kawamoto, Ariumi
Yunoki, Masashi
Kikuishi, Junya
Sakiyama, Toru
Abrégé
An adsorbent for oral administration comprising a spherical activated carbon which has many projections formed on the surface, i.e., in a number of 1-20 per 쎽m2, and has a total pore volume of 0.4-0.8 mL/g, and in which the proportion of pores having a diameter of 1 nm or smaller is 37-55 vol.%, the total acid group amount is 0.24-0.56 meq/g, and the ratio of the total acid group amount (a) to the total basic group amount (b), (a/b), is 0.60-2.00. The adsorbent highly adsorbs toxic substances such as DL-β-aminoisobutyric acid, indole, and indoxylsulfuric acid and lowly adsorbs substances necessary for the living body, such as α-amylase and lipase. The adsorbent is excellent in adsorption selectivity to such toxic substances.
ASAHI ORGANIC CHEMICALS INDUSTRY CO., LTD. (Japon)
Tomita Pharmaceutical Co., Ltd. (Japon)
Inventeur(s)
Matsumoto, Yasuhiro
Tomiyasu, Kei
Konishi, Koh
Konishi, Yukinori
Terada, Eri
Abrégé
An adsorbent for oral administration comprising a spherical active carbon of 0.2 to 0.5 cc/g total pore volume and 30 to 45% volume ratio of 1 nm or less diameter pores, provided on its surface with a multiplicity of projections. The adsorbent for oral administration has high capability of adsorbing harmful toxic substances, such as indole, while being low in the adsorptivity of in vivo needed substances, such as tryptophan and lysine, namely, excelling in the selective adsorption of harmful toxic substances.
A powder transport mechanism (16) stacks a powder layer composed mainly of a water soluble powder one layer by one layer on a shaping part (14). An ink jet line head (17) jets a water-based ink, which can dissolve the powder into a region according to the sectional shape of a shaped product in the uppermost powder layer stacked by a powder transport mechanism (16). A heater (18) heats the powder for each powder layer. The heater (18) heats the powder either after jetting of the water-based ink by the ink jet line head (17) or before jetting of the water-based ink by the ink jet line head (17). The present invention can be applied, for example, to a shaping apparatus.
Disclosed is a calcium hydrogen phosphate fine particle which is excellent in handleability and mixability, while maintaining good moldability. Specifically disclosed is a fine particle of a calcium hydrogen phosphate represented by the following formula: CaHPO4쮏nH2O (wherein n satisfies 0 ≤ n ≤ 0.5). This calcium hydrogen phosphate fine particle is characterized in that (1) the average secondary particle diameter of the fine particles is not more than 15 &mgr;m, and (2) the static bulk specific volume of the fine particles is less than 5 mL/g. Also specifically disclosed is a method for producing such a calcium hydrogen phosphate fine particle.
Disclosed is a core particle for a pharmaceutical preparation, which has properties required for a core particle, which is chemically stable, and which has reduced or inhibited reactivity with a medicinal substance (i.e., a pharmaceutically active ingredient). Specifically disclosed is a core particle for a pharmaceutical preparation, which is intended to have a coating film comprising a pharmaceutically active ingredient formed on its surface. The core particle is characterized as follows: (1) the core particle comprises a pharmaceutically acceptable inorganic material; (2) the inorganic material is poorly soluble in water; and (3) the inorganic material has a liquid pH value ranging from 5 to 8.
A pharmaceutical carrier contains a spherical particle structure which has a particle hardness of not lower than 200 g/mm2 and comprises at least one magnesium compound selected from magnesium hydroxide and magnesium oxide, is capable of preventing generation of cracks and powderization when a pharmaceutical is produced by coating the surface of a medicament in a fluidized state, and is capable of stably coating the chemically (such as an acid) unstable medicament without additionally performing coating with a basic substance, and further has a high disintegrability (solubility) in the gastrointestinal tract after oral administration as a pharmaceutical.
Moisture absorbent composition, moisture absorbent molding, and method for controlling equilibrium humidity, method for controlling time of maintaining equilibrium humidity
A moisture absorbent composition is provided with a thermoplastic resin; and a moisture absorbent kneaded into the thermoplastic resin, having a secondary particle size of substantially 1 to 40 μm, wherein equilibrium humidity is controlled by selecting the specific gravity of the thermoplastic resin. A method for controlling equilibrium humidity in a moisture absorbent composition obtained by kneading a moisture absorbent into a thermoplastic resin is provided, which includes kneading the moisture absorbent such that a secondary particle size of the moisture absorbent is substantially 1 to 40 μm; and controlling equilibrium humidity by selecting specific gravity of the thermoplastic resin.
B01D 53/14 - SÉPARATION Épuration chimique ou biologique des gaz résiduaires, p.ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par absorption
C08K 3/30 - Composés contenant du soufre, du sélénium ou du tellure
66.
DESICCANT COMPOSITION, MOLDED DESICCANT, METHOD OF CONTROLLING EQUILIBRIUM HUMIDITY FOR THE SAME, AND METHOD OF CONTROLLING EQUILIBRIUM HUMIDITY RETENTION TIME
A desiccant composition and a molded desiccant each comprising a thermoplastic resin compounded with a desiccant. The composition and the molded desiccant can be formulated so as to attain a different equilibrium humidity by replacement with a resin which is of the same kind but has a different specific gravity. Environments suitable for the preservation of a variety of products can be easily formed. The desiccant composition comprises a thermoplastic resin compounded with a desiccant having an equilibrium vapor pressure, the desiccant being magnesium sulfate represented by the formula MgSO4 nH2O (wherein 0≤n≤3). The surface of the desiccant is coated with a fatty acid metal salt before the desiccant is kneaded together with the thermoplastic resin so that the desiccant comes to have a secondary-particle diameter of 1-40 쎽m when dispersed in the thermoplastic resin. It has become possible to increase/reduce the equilibrium humidity by a given value with an increase/decrease in specific gravity by a certain value without changing the kind of the thermoplastic resin.
A process for producing a pattern, characterized by comprising: a step (a) in which a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder is spread in a plane on a table and then a spray liquid comprising at least one selected among water-miscible organic solvents and water is selectively sprayed through a nozzle on this powder mixture layer to make the bonding strength among particles of the powder mixture in the sprayed region higher than that among particles of the powder mixture in the unsprayed region; a step (b) in which the powder mixture is further spread on the powder mixture layer after spraying and then the spray liquid is sprayed through the nozzle on this powder mixture layer; a step (c) in which the step (b) is conducted repeatedly two or more times to form a pattern formed by the sprayed regions; and a step (d) in which the pattern is taken out.
B22C 9/10 - Noyaux; Fabrication ou mise en place des noyaux
B22C 1/00 - Compositions des matériaux réfractaires pour moules ou noyaux; Leur structure granulaire; Caractéristiques chimiques ou physiques de la mise en forme ou de la fabrication des moules
B29C 33/38 - Moules ou noyaux; Leurs détails ou accessoires caractérisés par la matière ou le procédé de fabrication
B29C 67/00 - Techniques de façonnage non couvertes par les groupes , ou