Abrégé

An electro-optic modulation structure 110, a method for fabrication of the electro-optic modulation structure, and a method of optical modulation derived from an electro-optic modulation structure with low voltage of operation are disclosed. The low voltage operation of the electro-optic modulator is realized by designed electro-optic modulation structures that include the light confining waveguide 114, overclad layer 120 and modulating electrode structure 116 for applying modulation voltages that are directed towards a low voltage operation of the electro-optic modulation 110 device upon consideration of optimal optical loss. (FIG. 3).

Classes IPC  ?

• G02F 1/03 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des céramiques ou des cristaux électro-optiques, p. ex. produisant un effet Pockels ou un effet Kerr
• B82Y 20/00 - Nano-optique, p. ex. optique quantique ou cristaux photoniques
• G02B 27/28 - Systèmes ou appareils optiques non prévus dans aucun des groupes , pour polariser
• G02F 1/035 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des céramiques ou des cristaux électro-optiques, p. ex. produisant un effet Pockels ou un effet Kerr dans une structure de guide d'ondes optique
• G02F 1/225 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur par interférence dans une structure de guide d'ondes optique
• G02F 1/31 - Dispositifs de déflexion numérique

Abrégé

A magnetically coupled ball drive system for actuation of spherical surfaces and wheels is disclosed. An internal support structure interacts with exterior drive wheels magnetically to produce rotational motion. A related improvement involving reduction of slip due to insufficient traction is also presented to establish a design for a more robust and versatile device that can be used in robotics or for producing vehicle locomotion.

Classes IPC  ?

• B60B 19/00 - Roues non prévues ailleurs ou ayant des caractéristiques précisées dans l'un des sous-groupes du présent groupe
• B60B 19/06 - Roues non prévues ailleurs ou ayant des caractéristiques précisées dans l'un des sous-groupes du présent groupe avec des compartiments pour liquides, ou pour matériaux de remplissage ou de chargeRoues flottantes
• B60B 19/14 - Roues en forme de sphères

Abrégé

Methods and devices for enhancing delivery of a biologically active molecule into a cell and/or increasing endosomal escape of mRNA within a cell. Methods and devices for improving delivery of a biologically active molecule across a cellular barrier or paracellularly.

Classes IPC  ?

• C12N 15/87 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p. ex. co-transformation
• C12N 13/00 - Traitement de micro-organismes ou d'enzymes par énergie électrique ou ondulatoire, p. ex. par magnétisme, par des ondes sonores
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine

Abrégé

The present invention relates to the manufacture and use of off-specification fly ash (OSFA), which would have otherwise been landfilled, in preparing ultra-high-performance concrete (UHPC). The present invention aims to provide a new avenue for valorization of OSFA in the concrete industry by utilizing high-volume OSFA in producing UHPC. Compared with conventional concrete and high-performance concrete, UHPC is a family of advanced concrete featuring exceptional compressive strength, ductility, and long-term durability. Application in UHPC is expected to be a new and feasible technology to efficiently recycle OSFA.

Classes IPC  ?

• C04B 28/04 - Ciments Portland
• C04B 14/06 - QuartzSable
• C04B 14/48 - Métaux
• C04B 16/06 - Composés macromoléculaires fibreux
• C04B 18/06 - Résidus de combustion, p. ex. produits d'épuration des fumées, des émanations ou des gaz d'échappement
• C04B 24/26 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
• C04B 103/30 - Réducteurs d'eau, plastifiants, entraîneurs d'air

Abrégé

Liposomes are leveraged to function as sacrificial templates for the growth of mesoporous nanostructures constructed with noble metals and other metals. Such templates allow for programmability for the specific distribution of metals and their properties while generating mesopores within the formed nanostructures. Ascorbic acid or other reductant is introduced to the sacrificial template for the reduction of metallic precursors. Once metallic precursors are added, the reductant finishes the reduction reaction to form the metallic nanostructures. Such nanostructures can have outside-in mesopores and pore diameters in the range of 10 nm to 50 nm.

Classes IPC  ?

• B22F 1/054 - Particules de taille nanométrique
• A61K 9/1271 - Liposomes non conventionnels, p. ex. liposomes modifiés par un PEG ou liposomes enduits de ou greffés avec des polymères
• A61K 9/1277 - Procédés de préparationProliposomes
• B22F 1/18 - Particules non métalliques revêtues de métal

Abrégé

A green-engineered mulch product and methods for making same are disclosed. The mulch product includes a coating of aluminum-based water treatment residuals which makes the product “green.” Furthermore, coating aluminum-based water treatment residuals on mulch eliminates the problem of the low hydraulic conductivity of aluminum-based water treatment residuals and makes it feasible to utilize its pollutant removal potential without requiring any modification to existing best management practices or additional maintenance.

Classes IPC  ?

• B01J 20/32 - Imprégnation ou revêtement
• B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
• B01J 20/24 - Composés macromoléculaires d'origine naturelle, p. ex. acides humiques ou leurs dérivés
• B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• C02F 101/20 - Métaux lourds ou leurs composés
• C02F 103/00 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter

Abrégé

A system and methods are disclosed for detecting logical fallacies and other forms of spurious reasoning. Artificial Intelligence methods allow for direct processing of input data in the form of text, an image and/or video. The system can be trained and refined through machine learning algorithms. The invention can be standalone or integrated as part of a larger platform (e.g., as part of a social media platform). Feedback can be provided to allow a user to write more effectively, refine their thinking process, and/or construct sounder, more persuasive arguments. The model can be trained through databases and/or with the help of human annotations of training data.

Classes IPC  ?

• G06F 40/30 - Analyse sémantique
• G06F 40/284 - Analyse lexicale, p. ex. segmentation en unités ou cooccurrence
• G06F 40/295 - Reconnaissance de noms propres

Abrégé

A sensor for blood-based measurement parameters that can be integrated on any flat surface to allow for ubiquitous monitoring of hemodynamics is disclosed. Such a sensor can measure heart rate, heart rate variability, blood pressure, etc. The sensor is adapted to be placed in direct contact with blood vessels. This can be done with an accelerometer or another type of vibrational or acoustic sensor in order to measure arterial vibrations.

Classes IPC  ?

• A61B 5/0295 - Mesure du débit sanguin utilisant la pléthysmographie, c.-à-d. par mesure des variations du volume d'une partie du corps induites par la circulation du sang qui traverse cette partie, p. ex. pléthysmographie par impédance
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
• A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
• A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
• A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/28 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électrocardiographie [ECG]

Abrégé

A minimally invasive device, containing a pressure channel, camera, and optical fiber imaging probe, to measure the stiffness of tissues in vivo and ex vivo is disclosed. The device is inserted into a patient and navigated to a tissue of interest, where stiffness is evaluated by applying suction and measuring the elongation or by applying compression force and measuring the compression of the tissue. Biopsies can be taken for further analysis, or tissue can be removed using an ablation laser. Small fluorescent molecules or therapeutics can also be delivered for improved visualization and targeted treatment. As such, this technology may be used to evaluate the stiffness of biomaterials as well as tissues and organs that are difficult to access, allowing for simultaneous diagnosis, treatment, and excision of diseased tissues.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
• A61B 18/24 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes en utilisant des lasers le faisceau étant dirigé le long, ou à l'intérieur d'un conduit flexible, p. ex. d'une fibre optiquePièces à main à cet effet avec un cathéter
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

Abrégé

Modular mucosal tissue bioreactors combined with bioartificial mucus provide a high-fidelity, medium-throughput platform for evaluating CF treatments and modeling host-pathogen biology, a stepping stone towards better options for HEMT-nonresponsive patients. Whole lung ex vivo Cystic Fibrosis model system allows for investigation of candidate CF therapies.

Classes IPC  ?

• C12M 1/14 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens fournissant des couches minces ou avec des plateaux à niveaux multiples
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Abrégé

Methods for more secure mobile network communications are disclosed. Specifically, details involving natural language processing (NLP) based auto formal modeling of protocols and specifications with large language models (NLP) are provided. Methods for formal and fuzzing amplification for fuzz testing to detect vulnerabilities are also disclosed. Furthermore, solutions are provided to identified vulnerabilities in existing 5G infrastructures. Also disclosed is a digital twin fuzzing framework.

Classes IPC  ?

• G06F 21/57 - Certification ou préservation de plates-formes informatiques fiables, p. ex. démarrages ou arrêts sécurisés, suivis de version, contrôles de logiciel système, mises à jour sécurisées ou évaluation de vulnérabilité
• G06N 5/048 - Inférence floue

Abrégé

Methods for more secure mobile network communications are disclosed. Specifically, details involving natural language processing (NLP) based auto formal modeling of protocols and specifications with large language models (NLP) are provided. Methods for formal and fuzzing amplification for fuzz testing to detect vulnerabilities are also disclosed. Furthermore, solutions are provided to identified vulnerabilities in existing 5G infrastructures. Also disclosed is a digital twin fuzzing framework.

Classes IPC  ?

• H04L 9/40 - Protocoles réseaux de sécurité
• G06F 40/20 - Analyse du langage naturel

Abrégé

A method for authentication between multiple communication parties is disclosed. Authentication can be carried out by the means of each communication party having a device having a physical unclonable function. To make this possible, the devices have a known quantum correlation that can be used in conjunction with entangled photons to verify the identities of the devices.

Classes IPC  ?

• H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
• G06F 21/44 - Authentification de programme ou de dispositif
• H04L 9/08 - Répartition de clés

Abrégé

A process includes means for depositing an anti-corrosion coating filled with liquid oil on an aluminum substrate. Aluminum is anodized and then treated with a thin hydrophobic sub-coating. The pores created through anodization are then impregnated with liquid oil. Oil penetration is maximized and residual air is minimized by first filling the pores with a filling solution, replacing the filling solution with an exchange fluid, and then replacing the exchange fluid with perfluorinated oil. The oil gives the surface coating anti-wetting properties and self-healing properties, thereby protecting the aluminum substrate underneath from corrosion.

Classes IPC  ?

• C25D 11/24 - Post-traitement chimique
• C25D 11/10 - Anodisation de l'aluminium ou de ses alliages caractérisée par les électrolytes utilisés contenant des acides organiques

Abrégé

Methods useful for the manufacturing of microfluidic cells useful in electronics and other applications are disclosed. In this technique, an air cushioned pressure supplies the force to bond a membrane, which can be made from one or more of the sulfonated tetrafluoroethylene polymers commercially known as Nafion™ (i.e., proton exchange membranes) or from other thermoplastic substrates. A substrate is compressed and templated while it is simultaneously sealed inside the cell. The resultant microcells are strongly sealed while being patterned according to their application.

Classes IPC  ?

• H01M 8/1004 - Éléments à combustible avec électrolytes solides caractérisés par les ensembles membrane-électrodes [MEA]

Abrégé

What is presented herein is a robust sacrificial strategy to create hierarchical and perfusable microchannel networks within versatile scaffolds via the combination of embedded 3D printing (EB3DP), tunable poly electrolyte complexes (PEC), and casting methods. The sacrificial templates of PEC filaments (diameter from 100 to 500 pm) with arbitrary 3D configurations can be fabricated by EB3DP and then incorporated into various castable matrices (e.g., hydrogels, organic solutions, meltable polymers, etc.). Rapid dissolution of PEC templates within a 2.00 M potassium bromide aqueous solution leads to the high-fidelity7 formation of interconnected channels for free mass exchange. Continuous cell proliferation and ECM deposition is seen as a result. Subcutaneous implantation of channeled silk fibroin (SF) scaffolds with a porosity of 76% could lead to tissue ingrowth as high as 53%. Both histological and immunofluorescence analyses demonstrate that such channeled scaffolds promoted cellularization, vascularization, and host integration along with immunoregulation.

Classes IPC  ?

• A61L 27/14 - Matériaux macromoléculaires
• A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
• A61L 27/56 - Matériaux poreux ou cellulaires
• B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive

Abrégé

A biomaterial structure for proliferation of stem cells includes at least one lattice sub-structure, and a structural gradient in which one or more geometrical features of the biomaterial structure varies along at least one dimension of the biomaterial structure in three-dimensional space. In some embodiments, the structural gradient is accomplished by the first and second lattice sub-structures having at least one different geometrical parameter.

Classes IPC  ?

• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 50/00 - Acquisition ou traitement de données pour la fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive
• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus

Abrégé

A bioreactor is disclosed that can be used to study living tissues (e.g., lung tissues) in an environment that mimics the natural environment. Pressure, flow and force modules enable imitation of in vivo conditions. An integrated imaging module allows for the airway tissues and cells of interest to be visualized and monitored continuously and non-destructively at the single-cell level. A method of use of the created systems can be utilized to quantify mucociliary fluid movements across the luminal surface of in vitro-cultured human airway tissue via in situ particle tracking and analysis is also disclosed. Another method of use of systems created in accordance with an embodiment of the present invention is to generate in vitro-cultured human airway tissue with severely impaired mucociliary flow by depositing thick viscous mucus-mimetic fluid on to the airway lumen. Methods of de-epithelialization and replacement of living cells are also disclosed.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux

Abrégé

The present disclosure provides polymeric matrices comprising calreticulin (CRbT) and methods of producing and using such matrices. The polymeric matrices are useful in treatment of wounds (e.g., chronic diabetic wound).

Classes IPC  ?

• A61K 9/70 - Bases pour bande, feuille ou filament
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61L 27/22 - Polypeptides ou leurs dérivés
• A61L 31/04 - Matériaux macromoléculaires
• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
• D01D 5/00 - Formation des filaments, fils ou similaires
• A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
• A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires

Abrégé

Apparatus and methods are disclosed to assess tissue properties, especially those of lung tissues. By measuring impedance in response to electrical stimulation, a variety of properties can be deduced including spatial location of damaged tissue, presence of epithelial cells and function of diseased tissue. To these ends, a probe (10) with electrodes (12, 14, 16, 18) connected to an impedance analyzer (20) was developed for assessing tissue (22) function. By applying voltages and/or currents, different information can be determined. In another embodiment, such a probe can be used for electroporation to evaluate the location of genetic molecules (e.g., RNA, DNA, or gene-editing machinery) and/or encourage their transport across different layers of tissue (FIG. 11).

Classes IPC  ?

• A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p. ex. laryngoscopes, bronchoscopes
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires

Abrégé

A method of treating a patient having edematous lungs includes: administering a first surface tension-lowering component to the patient via the airways and administering a second surface tension-lowering component to the patient via the vasculature. The combined and complementary treatments may lower or normalize alveolar surface tension with improved efficiency and on a faster timescale, thereby reducing patient injury and mortality (FIG. 1).

Classes IPC  ?

• A61K 38/38 - Albumines
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains

Abrégé

Systems and methods associated with a bioreactor are disclosed. An imaging module is provided that allows for in situ observation of, for instance, lung tissue. Various compounds can be introduced into a cell culture chamber for experimental and practical applications on epithelial tissue. Methods and apparatus are also provided for deepithelializing human or rat tissue without damaging the structures underneath. Thereafter, cell-growth can be effected in a homogenous distribution.

Classes IPC  ?

• C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
• C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse

Abrégé

Three artificial intelligence (AI) linguistic processing architectures are proposed for early detection of Alzheimer's Disease based entirely on a patient's language abilities. Three C-Attention network architectures are presented: one that uses only PoS features, one that uses only the latent features (e.g., language embeddings) and a unified architecture, which uses both features.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

A quantitative gait training and/or analysis system includes one or more footwear modules that may include a piezoresistive sensor, an inertial sensor and an independent logic unit. The footwear module functions to permit the extraction of gait kinematics and evaluation thereof in real time, or data may be stored for later reduction and analysis. Embodiments relating to calibration-based estimation of kinematic gait parameters are described, as well as biofeedback embodiments useful in training runners to maintain a time-varying target velocity or pace.

Classes IPC  ?

• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

Filter media for treating contaminated water is produced from aluminum-based water treatment residuals (Al-WTR) commonly produced as a byproduct of water treatment plants. By processing the residuals into small granules, a superior green sorbent product is obtained with the functionality to adsorb contaminants, such as metals and certain nutrients in water. Biopolymers can be incorporated into the filter media to further enhance functionality and hydraulic characters.

Classes IPC  ?

• B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
• B01D 39/20 - Autres substances filtrantes autoportantes en substance inorganique, p. ex. papier d'amiante ou substance filtrante métallique faite de fils métalliques non-tissés
• B01D 39/16 - Autres substances filtrantes autoportantes en substance organique, p. ex. fibres synthétiques
• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• B01J 20/24 - Composés macromoléculaires d'origine naturelle, p. ex. acides humiques ou leurs dérivés
• B01J 20/30 - Procédés de préparation, de régénération ou de réactivation

Abrégé

The present invention relates to methods for secure computation and/or communication. Entangled photons (118) are generated such that each participating party receives a series of optical pulses. Each party has private information (110, 112) which are never transmitted through public or private communication channels. Instead, each party converts their respective private information (110, 112) into measurement bases via an encryption process (114, 116) which are then applied to the entangled photons (118). After the measurement process, e.g., quantum frequency conversion (122, 124), reference indices are announced (124, 126) so that computation can be performed (128) without revealing the private information directly or indirectly.

Classes IPC  ?

• H04L 9/08 - Répartition de clés

Abrégé

The present invention relates to the manufacture and use of off-specification fly ash (OSFA), which would have otherwise been landfilled, in preparing ultra-high-performance concrete (UHPC). The present invention aims to provide a new avenue for valorization of OSFA in the concrete industry by utilizing high-volume OSFA in producing UHPC. Compared with conventional concrete and high-performance concrete, UHPC is a family of advanced concrete featuring exceptional compressive strength, ductility, and long-term durability. Application in UHPC is expected to be a new and feasible technology to efficiently recycle OSFA (FIG. 1).

Classes IPC  ?

• C04B 28/04 - Ciments Portland
• C04B 18/08 - Cendres volantes
• C04B 40/06 - Inhibition de la prise, p. ex. pour mortiers du type à action différée contenant de l'eau dans des récipients frangibles

Abrégé

In accordance with the method of the present invention, 3D tissue-derived scaffolding materials are made in various formats, including but not limited to hydrogel, sponge, fibers, microspheres, and films, all of which function to better preserve natural extracellular matrix molecules and to mimic the natural tissue environment, thereby effectively guiding tissue regeneration. The method involves incorporating a homogenized tissue-derived suspension into a polymeric solution of synthetic, natural, or hybrid polymers to prepare tissue-derived scaffolds in the aforementioned formats. Such tissue-derived scaffolds and scaffolding materials have a variety of utilities, including: the creation of 3D tissue models such as skin, bone, liver, pancreas, lung, and so on; facilitation of studies on cell-matrix interactions; and the fabrication of implantable scaffolding materials for guided tissue formation in vivo. The tissue-derived scaffolds and scaffolding materials made in accordance with the present invention also provide the opportunity to correlate the functions of extracellular matrix with tissue regeneration and cancer metastasis, for example.

Classes IPC  ?

• A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
• A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 27/52 - Hydrogels ou hydrocolloïdes
• A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 27/56 - Matériaux poreux ou cellulaires
• A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
• A61L 27/60 - Matériaux utilisables pour la peau artificielle
• C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

The present invention relates generally to the manufacture of conductive scaffolds of micro and/or nanofibers with the help of different printing techniques (e.g., near-field electrostatic printing, inkjet printing), such scaffolds enabling the formation of two-dimensional (2D) or three-dimensional (3D) neural networks to mimic the native counterparts. Applications of such patterned conductive scaffolds include, but are not limited to, an engineered conduit for guiding the differentiation and outgrowth of neural cells in peripheral nerve damage or in large-volume spinal cord injury under the electrical stimulation. Meanwhile, the scaffolds could also locally deliver various biomolecules in conjunction with electrical stimulation for facilitated nervous system regeneration.

Classes IPC  ?

• A61B 17/11 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour réaliser l'anastomoseBoutons pour anastomose
• A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 31/10 - Matériaux macromoléculaires
• A61L 31/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 40/20 - Posttraitement, p. ex. durcissement, revêtement ou polissage
• B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive
• B41M 5/00 - Procédés de reproduction ou méthodes de reproduction ou de marquageMatériaux en feuilles utilisés à cet effet
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques

Abrégé

A method for producing doped, van der Waals ferromagnetic materials is disclosed. Such materials can take the form of monolayer iron-doped transition metal dichalcogenides. Such materials are useful for the manufacture of semiconductors, as high curie temperatures are achieved (i.e., those exceeding room temperature), which allows for the preservation of useful ferromagnetic and semiconducting properties across a wider range of conditions.

Classes IPC  ?

• H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
• C01G 39/06 - Sulfures
• C23C 16/30 - Dépôt de composés, de mélanges ou de solutions solides, p. ex. borures, carbures, nitrures
• C23C 14/08 - Oxydes
• C23C 16/40 - Oxydes
• C23C 28/04 - Revêtements uniquement de matériaux inorganiques non métalliques
• C23C 16/56 - Post-traitement
• C23C 14/30 - Évaporation sous vide par énergie éléctromagnétique ou par rayonnement corpusculaire par bombardement d'électrons
• H10N 50/10 - Dispositifs magnéto-résistifs

Abrégé

Approaches, apparatuses and methods for single photon sensitive, non-interferometric photonics vibrometry applications based on quantum parametric mode sorting, optical gating and single photon counting are disclosed. In one embodiment, a controller module includes a photon detection unit, a pulse generator unit, a time synchronization unit, a data acquisition and processing unit and a central controller unit. In the second embodiment, a probe module with beam raster scanning ability includes an optical transceiver unit based on a bidirectional monostatic coaxial arrangement using off-the-shelf optical components and an optical beam steering device.

Classes IPC  ?

• G01H 9/00 - Mesure des vibrations mécaniques ou des ondes ultrasonores, sonores ou infrasonores en utilisant des moyens sensibles aux radiations, p. ex. des moyens optiques
• H01S 3/1106 - Blocage de modes
• H01S 3/00 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet
• H01S 3/094 - Procédés ou appareils pour l'excitation, p. ex. pompage utilisant le pompage optique par de la lumière cohérente

Abrégé

A sensor apparatus for footwear includes at least one pair of light sources and at least one pair of light receivers, each light receiver being positioned and configured to receive light emitted from a respective one of the light sources. A pair of movable curtains functions to adjust the amount of light received by the pair of light receivers. The curtains are movable conjointly such that the amount of light received by one of the light receivers is inversely proportional to the amount of light received by the other light receiver. (FIG. 1B).

Classes IPC  ?

• G01N 3/24 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant des efforts permanents de cisaillement

Abrégé

An electro-optic modulation structure 110, a method for fabrication of the electro-optic modulation structure, and a method of optical modulation derived from an electro-optic modulation structure with low voltage of operation are disclosed. The low voltage operation of the electro-optic modulator is realized by designed electro-optic modulation structures that include the light confining waveguide 114, overclad layer 120 and modulating electrode structure 116 for applying modulation voltages that are directed towards a low voltage operation of the electro-optic modulation 110 device upon consideration of optimal optical loss.

Classes IPC  ?

• G02B 27/28 - Systèmes ou appareils optiques non prévus dans aucun des groupes , pour polariser
• G02F 1/03 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des céramiques ou des cristaux électro-optiques, p. ex. produisant un effet Pockels ou un effet Kerr
• G02F 1/035 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des céramiques ou des cristaux électro-optiques, p. ex. produisant un effet Pockels ou un effet Kerr dans une structure de guide d'ondes optique
• G02F 1/225 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur par interférence dans une structure de guide d'ondes optique
• B82Y 20/00 - Nano-optique, p. ex. optique quantique ou cristaux photoniques
• G02F 1/31 - Dispositifs de déflexion numérique

Abrégé

A method for creating oil-filled porous anodic oxide coatings for stainless steel is disclosed. The coating has anti-corrosion and omniphobic properties to resist both atmospheric conditions, or other conditions with exposure to vapor, and wet conditions, in which the coating is exposed to and/or immersed in liquid. The anodic oxide coating of the present invention can be made by the steps of cleaning and/or electropolishing a steel substrate, applying anodic oxidation to the steel substrate, washing the steel substrate in an organic solvent, and annealing the substrate at high temperature. To fill the porous coating with an oil, a solvent exchange method may be applied.

Classes IPC  ?

• C25D 5/48 - Post-traitement des surfaces revêtues de métaux par voie électrolytique
• C09D 5/08 - Peintures anti-corrosion
• C09D 127/18 - Homopolymères ou copolymères du tétrafluoro-éthylène
• C25D 11/02 - Anodisation
• C25F 3/24 - Polissage des métaux lourds du fer ou de l'acier
• C25D 5/36 - Prétraitement des surfaces métalliques à revêtir de métaux par voie électrolytique de fer ou d'acier

Abrégé

An optical computation system includes a light source configured to produce a pump beam, an optical modulator configured to modulate the pump beam based on the modulation mask to generate a modulated beam, a non-linear medium configured to convert a portion of the modulated beam to a second harmonic (SH) beam and to produce an output including the SH beam and an unconverted portion of the pump beam, and a dichroic mirror configured to receive the output of the non-linear medium and to decouple the SH beam and the unconverted portion of the pump beam, a detector configured to detect a first optical power of the unconverted portion of the pump beam and to detect a second optical power of the SH beam, and a controller configured to generate an updated modulation mask based on the first and second optical powers for transmission to the optical modulator.

Classes IPC  ?

• G02F 1/37 - Optique non linéaire pour la génération de l'harmonique deux
• G06E 1/02 - Dispositions pour traiter exclusivement des données numériques agissant sur l'ordre ou le contenu des données maniées
• G02F 1/355 - Optique non linéaire caractérisée par les matériaux utilisés
• G02F 1/39 - Optique non linéaire pour la génération ou l'amplification paramétrique de la lumière, des infrarouges ou des ultraviolets

Abrégé

A method for creating oil-filled porous anodic oxide coatings for metallic surfaces is disclosed. The coating has anti-corrosion and omniphobic properties to resist both underwater and atmospheric conditions. To realize oil-impregnated three-dimensional bottle-shaped pores in the oxide layer in anodizing aluminum, the following steps may be taken. First, the target surface may be cleaned and electropolished. Then, a first anodizing step at a lower voltage is applied to create relatively small-diameter pores in the entrance (i.e., top) region of the oxide layer, followed by a second anodizing step at a higher voltage to subsequently create larger-diameter pores in the base (i.e., bottom) region of the oxide layer. Pore widening follows to enlarge the overall pore diameters. To fill the porous coating with an oil, a solvent exchange method may be utilized.

Classes IPC  ?

• C25D 11/04 - Anodisation de l'aluminium ou de ses alliages
• C25D 11/18 - Post-traitement, p. ex. bouchage des pores

Abrégé

A periodically poled microring resonator structure, a method for fabrication of the periodically poled microring resonator structure, and a method to achieve giant single-photon nonlinearity are disclosed. The strong single-photon nonlinearity in the microring resonator structure is achieved through its optimized design and fabrication procedures.

Classes IPC  ?

• G02F 1/365 - Optique non linéaire dans une structure de guide d'ondes optique
• G02F 1/355 - Optique non linéaire caractérisée par les matériaux utilisés
• G02F 1/35 - Optique non linéaire

Abrégé

The present invention relates to methods for secure computation and/or communication. Entangled photons (118) are generated such that each participating party receives a series of optical pulses. Each party has private information (110, 112) which are never transmitted through public or private communication channels. Instead, each party converts their respective private information (110, 112) into measurement bases via an encryption process (114, 116) which are then applied to the entangled photons (118). After the measurement process, e.g., quantum frequency conversion (122, 124), reference indices are announced (124, 126) so that computation can be performed (128) without revealing the private information directly or indirectly.

Classes IPC  ?

• H04L 9/08 - Répartition de clés

Abrégé

A green-engineered mulch product and methods for making same are disclosed. The mulch product includes a coating of aluminum-based water treatment residuals which makes the product "green." Furthermore, coating aluminum-based water treatment residuals on mulch eliminates the problem of the low hydraulic conductivity of aluminum-based water treatment presiduals and makes it feasible to utilize its pollutant removal potential without requiring any modification to existing best management practices or additional maintenance.

Classes IPC  ?

• B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
• B01J 20/32 - Imprégnation ou revêtement
• B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
• B01J 20/24 - Composés macromoléculaires d'origine naturelle, p. ex. acides humiques ou leurs dérivés
• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• C02F 103/00 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter

Abrégé

A method of treating tissue, the method comprising: applying a biochemical agent to a surface of a target tissue, and pulsing low intensity focused acoustic waves from an acoustic energy source toward the target tissue, such that the low intensity focused acoustic waves are pulsed at a frequency and amplitude that does not induce boiling or cavitation of the target tissue, thereby selectively removing cells of the target tissue by the low intensity acoustic waves, while leaving healthy cells of the target tissue substantially intact.

Classes IPC  ?

• A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins

Abrégé

A method of localizing brain regions for the purpose of guiding placement of electrodes and related implants is disclosed. The inventive method involves effecting a pulse in a patient's brain, temporally aligning readings taken from an electrode at various depths, measuring local field potentials at each depth during interstimulus intervals, performing a coherence analysis comparing the local field potential measurements of the different depths, and determining a corresponding brain region for the depths compared.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
• A61B 5/377 - Électroencéphalographie [EEG] utilisant des réponses provoquées
• A61N 1/08 - Aménagements ou circuits de surveillance, de protection, de commande ou d'indication
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

in vivo ex vivoex vivo is disclosed. The device is inserted into a patient and navigated to a tissue of interest, where stiffness is evaluated by applying suction and measuring the elongation or by applying compression force and measuring the compression of the tissue. Biopsies can be taken for further analysis, or tissue can be removed using an ablation laser. Small fluorescent molecules or therapeutics can also be delivered for improved visualization and targeted treatment. As such, this technology may be used to evaluate the stiffness of biomaterials as well as tissues and organs that are difficult to access, allowing for simultaneous diagnosis, treatment, and excision of diseased tissues.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G01N 3/40 - Recherche de la dureté ou de la dureté au rebondissement
• G01N 33/483 - Analyse physique de matériau biologique

Abrégé

A spectroscope using single-photon counters and a chip-integrated lithium niobate micro-ring filter to measure the atmospheric CO2 absorption spectrum passively is disclosed. By thermo-optically sweeping the filter over 150 pm and referencing the resulting photon counts to a bypass channel, the absorption spectrum can be sampled at an ultrahigh-resolution of 6 pm. The spectroscope can be a part of a ground-based field system, wherein the CO2 absorption through the atmosphere can be characterized by counting the solar photons across the absorption line around 1572.02 nm, which agrees well with its transmission spectrum at standard atmospheric pressure.

Classes IPC  ?

• G01N 21/31 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique
• G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
• G02B 6/293 - Moyens de couplage optique ayant des bus de données, c.-à-d. plusieurs guides d'ondes interconnectés et assurant un système bidirectionnel par nature en mélangeant et divisant les signaux avec des moyens de sélection de la longueur d'onde

Abrégé

A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment.

Classes IPC  ?

• H04L 67/30 - Profils
• H04L 67/306 - Profils des utilisateurs
• H04W 4/02 - Services utilisant des informations de localisation
• H04W 4/029 - Services de gestion ou de suivi basés sur la localisation
• H04W 4/30 - Services spécialement adaptés à des environnements, à des situations ou à des fins spécifiques
• H04W 88/08 - Dispositifs formant point d'accès
• H04W 84/12 - Réseaux locaux sans fil [WLAN Wireless Local Area Network]
• H04W 4/33 - Services spécialement adaptés à des environnements, à des situations ou à des fins spécifiques pour les environnements intérieurs, p. ex. les bâtiments

Abrégé

Process and apparatus (10) are disclosed for capturing and converting an ozone-depleting alkyl halide fumigant from a fumigant/air mixed stream (14) by absorbing it into a metal hydroxide-alcohol buffer solution (26) in an absorber/scrubber (12) to produce a fumigant-free air stream (28). The captured alkyl halide in aqueous alcohol solution can actively react with the metal hydroxide in alcohol solution to produce a value-added product, such as a precipitate metal halide, and another alcohol that further enhances absorption. The absorbing solution is well-mixed with make-up alcohol and alkali streams to maintain the concentration of the metal hydroxide in the desired buffer solution range. The solid precipitate metal halide (52) is separated from the liquid stream, and the metal hydroxide-containing mixed alcohol stream (26) is recycled to the absorber/scrubber (12).

Classes IPC  ?

• B01D 53/18 - Unités d'absorptionDistributeurs de liquides
• B01D 53/70 - Composés halogénés organiques
• B01D 53/78 - Procédés en phase liquide avec un contact gaz-liquide

Abrégé

The disclosed subject matter relates to a device, system and method for locating and repairing a pulmonary air leak in a patient.

Classes IPC  ?

• A61B 7/00 - Instruments d'auscultation
• A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
• A61B 7/04 - Stéthoscopes électriques

Abrégé

Smart membranes (14) are integrated into a small, unmanned surface vessel (20) to enable the efficient, automated cleanup of oil spills. Such a vessel (20) has the potential to provide a low-cost, modular solution for day-to-day oil-spill cleanup operations, especially in confined aquatic areas, such as under piers and in the small spaces between marine vessels and piers. The smart membranes (14) are provided on the surface of a conveyor belt (34) that circulates the membranes (14) through the surrounding body of water (10) for oil collection, as well as through an internal reduction chamber (22) of the vessel (20) for oil release. The smart membranes (14) are adapted to attract and repel oil (12) in response to low-voltage commands applied across the conveyor belt (34), using a process that is repeatable for a number of cycles, offering high efficiency and long durability (FIG. 5).

Classes IPC  ?

• C02F 1/40 - Dispositifs pour séparer ou enlever les substances grasses ou huileuses, ou les matières flottantes similaires
• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
• C02F 101/32 - Hydrocarbures, p. ex. huiles
• C02F 103/00 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter

Abrégé

A method for authentication between multiple communication parties is disclosed. Authentication can be carried out by the means of each communication party having a device having a physical unclonable function. To make this possible, the devices have a known quantum correlation that can be used in conjunction with entangled photons to verify the identities of the devices.

Classes IPC  ?

• G09C 1/00 - Appareils ou méthodes au moyen desquels une suite donnée de signes, p. ex. un texte intelligible, est transformée en une suite de signes inintelligibles en transposant les signes ou groupes de signes ou en les remplaçant par d'autres suivant un système préétabli
• H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
• H04L 9/08 - Répartition de clés
• H04L 9/00 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité

Abrégé

A quantitative gait training and/or analysis system includes one or more footwear modules that may include a piezoresistive sensor, an inertial sensor and an independent logic unit. The footwear module functions to permit the extraction of gait kinematics and evaluation thereof in real time, or data may be stored for later reduction and analysis. Embodiments relating to calibration-based estimation of kinematic gait parameters are described.

Classes IPC  ?

• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

Methods useful for the manufacturing of microfluidic cells useful in electronics and other applications are disclosed. In this technique, an air cushioned pressure supplies the force to bond a membrane, which can be made from one or more of the sulfonated tetrafluoroethylene polymers commercially known as Nafion™ (i.e., proton exchange membranes) or from other thermoplastic substrates. A substrate is compressed and templated while it is simultaneously sealed inside the cell. The resultant microcells are strongly sealed while being patterned according to their application.

Classes IPC  ?

• H01M 8/1004 - Éléments à combustible avec électrolytes solides caractérisés par les ensembles membrane-électrodes [MEA]
• H01M 8/10 - Éléments à combustible avec électrolytes solides

Abrégé

The present disclosure relates to an apparatus and method for synthetically making an ultra-wide imaging bandwidth in millimeter-wave frequencies, resulting in improved image resolutions to values previously unattained. The synthetic approach sums up a number of available sub-bands to build an unavailable ultra-wideband system. Each sub-band contains a transceiver unit which is optimized for operation within that specific sub-band. The number and position of the sub-bands can be adjusted to cover any frequency range as required for the specific application.

Classes IPC  ?

• G01S 13/90 - Radar ou systèmes analogues, spécialement adaptés pour des applications spécifiques pour la cartographie ou la représentation utilisant des techniques d'antenne synthétique
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
• G01S 7/03 - Détails de sous-ensembles HF spécialement adaptés à ceux-ci, p. ex. communs à l'émetteur et au récepteur
• G01S 13/02 - Systèmes utilisant la réflexion d'ondes radio, p. ex. systèmes du type radar primaireSystèmes analogues
• G01S 13/34 - Systèmes pour mesurer la distance uniquement utilisant la transmission d'ondes continues, soit modulées en amplitude, en fréquence ou en phase, soit non modulées utilisant la transmission d'ondes continues modulées en fréquence, tout en faisant un hétérodynage du signal reçu, ou d’un signal dérivé, avec un signal généré localement, associé au signal transmis simultanément

Abrégé

The present invention relates to a method for creating an individualized machine learning inference model. In accordance with the invention, the aforementioned method and a related system involve a motion capture device adapted to be worn by a user. The motion capture device is adapted to acquire measurements, which are used to compute a first estimate of one or more gait parameters. Next, a database is accessed that contains previously collected observations of gait data and the first estimate is compared to the previously collected observations of gait data. Finally, the subset of previously collected observations of gait data that is most informative for the particular user is identified and the individualized machine learning inference model can be developed using the identified subset of previously collected observations of gait data.

Classes IPC  ?

• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic

Abrégé

A biomaterial structure for proliferation of stem cells includes at least one lattice sub-structure, and a structural gradient in which one or more geometrical features of the biomaterial structure varies along at least one dimension of the biomaterial structure in three-dimensional space. In some embodiments, the structural gradient is accomplished by the first and second lattice sub-structures having at least one different geometrical parameter.

Classes IPC  ?

• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse

Abrégé

One or more systems and methods according to the present disclosure may apply a model for integrating distribution systems having proliferated distributed energy resources into the independent system operator energy market, particularly when one or more distribution systems are connected to a transmission system via multiple interconnection buses. Additionally, systems and methods for applying a compact multi-port model for power exchanges and associated bidding strategies are described. A the multi-port power exchange model may be constructed based on the operational feasible region of a distribution system; describing physical operation characteristics of distributed energy resources, flexible loads, and the distribution network; and the bidding strategy model may describe total operating cost of the distribution system, while recognizing electrically coupled injections of multiple interconnection buses.

Classes IPC  ?

• G06Q 30/0202 - Prédictions ou prévisions du marché pour les activités commerciales
• G05F 3/04 - Régulation de la tension ou du courant là où la tension ou le courant sont alternatifs
• G06F 17/14 - Transformations de Fourier, de Walsh ou transformations d'espace analogues
• G06Q 50/06 - Fourniture d’énergie ou d’eau
• H02J 3/00 - Circuits pour réseaux principaux ou de distribution, à courant alternatif

Abrégé

A method of treating a patient having edematous lungs includes: administering a first surface tension-lowering component to the patient via the airways and administering a second surface tension-lowering component to the patient via the vasculature. The combined and complementary treatments may lower or normalize alveolar surface tension with improved efficiency and on a faster timescale, thereby reducing patient injury and mortality.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/08 - Solutions
• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
• A61K 38/38 - Albumines
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains

Abrégé

A process includes means for depositing an anti-corrosion coating filled with liquid oil on an aluminum substrate. Aluminum is anodized and then treated with a thin hydrophobic sub-coating. The pores created through anodization are then impregnated with liquid oil. Oil penetration is maximized and residual air is minimized by first filling the pores with a filling solution, replacing the filling solution with an exchange fluid, and then replacing the exchange fluid with perfluorinated oil. The oil gives the surface coating anti-wetting properties and self-healing properties, thereby protecting the aluminum substrate underneath from corrosion.

Classes IPC  ?

• C25D 11/24 - Post-traitement chimique
• C25D 11/10 - Anodisation de l'aluminium ou de ses alliages caractérisée par les électrolytes utilisés contenant des acides organiques

Abrégé

Smart membranes are integrated into a small, unmanned surface vessel to enable the efficient, automated cleanup of oil spills. Such a vessel has the potential to provide a low-cost, modular solution for day-to-day oil-spill cleanup operations, especially in confined aquatic areas (e.g., under piers or in the small spaces between marine vessels and piers). The membranes are provided on the surface of a conveyor belt that circulates the membranes through the surrounding body of water for oil collection, as well as through an internal reduction chamber of the vessel for oil release. The smart membranes are adapted to attract and repel oil in response to low-voltage commands applied across the conveyor belt, using a process that is repeatable for a number of cycles, offering high efficiency and long durability. Segments of the conveyor belt can be electrically isolated from one another to allow disparate electrical potentials to be imposed thereon.

Classes IPC  ?

• C02F 1/40 - Dispositifs pour séparer ou enlever les substances grasses ou huileuses, ou les matières flottantes similaires
• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• C02F 101/32 - Hydrocarbures, p. ex. huiles
• C02F 103/00 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter

Produits et services

Educational publications, namely, printed educational materials, guides, books, pamphlets, brochures and hand-outs in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation; stationery; printed posters; fundraising publications, namely, printed pamphlets, brochures and booklets featuring fundraising information; printed newsletters and magazines in the field of general interest for alumni Banners of textile or plastic; flags of textile or plastic; tablecloths of textile; tablecloths, not of paper Clothing, namely, hats, caps being headwear, jackets, jerseys, shirts, polo shirts, wind shirts, tank tops, shorts, sweatpants, sweatshirts, sweaters, socks, T-shirts and vests Career counseling, namely, providing career planning and placement advice concerning options to pursue career opportunities; research, including academic research in the fields of engineering management, namely, project management for business purposes Educational services, namely, providing undergraduate and graduate level courses in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, premedicine, sports technologies and digital transformation; providing classes, seminars and workshops in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, premedicine, sports technologies and digital transformation; development of educational materials, including reference materials for others in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation; conducting distance learning in the nature of courses at the university level via the Internet in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation; providing a website via a global computer network with educational information in the academic fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation for the purposes of academic study; providing non-downloadable educational electronic publications in the nature of electronic magazines and articles in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation via the Internet; providing college sport exhibition events and recreation programs, namely, athletic competitions; providing dramatic and musical entertainment events, including live and pre-recorded performances, namely, live plays and musical performances, and screening of pre-recorded films; providing a website featuring information on educational courses, educational and entertainment programs, educational and cultural events, current events news, and recreational and leisure activities in the arts and humanities; educational counseling services to assist students in planning and preparing for further education, and career counseling, namely, providing educational advice concerning options to pursue career opportunities; providing a website featuring information on educational courses and undergraduate and graduate programs in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation; providing information on current events relating to science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation Providing information in the field of computer systems engineering; research, including academic research and scientific research, in the fields of science, technology, engineering, quantum science and engineering, robotics, science and new technology feasibility studies, mathematics, computer enterprise project management, computer science, cybersecurity, data science, computer information systems, and artificial intelligence and machine learning Licensing of technology, namely, licensing of intellectual property

Produits et services

Educational publications, namely, printed educational materials, guides, books, pamphlets, brochures and hand-outs in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation; stationery; printed posters; fundraising publications, namely, printed pamphlets, brochures and booklets featuring fundraising information; printed newsletters and magazines in the field of general interest for alumni Banners of textile or plastic; flags of textile or plastic; tablecloths of textile; tablecloths, not of paper Clothing, namely, hats, caps being headwear, jackets, jerseys, shirts, polo shirts, wind shirts, tank tops, shorts, sweatpants, sweatshirts, sweaters, socks, T-shirts and vests Career counseling, namely, providing career planning and placement advice concerning options to pursue career opportunities; research, including academic research in the fields of engineering management, namely, project management for business purposes Educational services, namely, providing undergraduate and graduate level courses in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, premedicine, sports technologies and digital transformation; providing classes, seminars and workshops in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, premedicine, sports technologies and digital transformation; development of educational materials, including reference materials for others in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation; conducting distance learning in the nature of courses at the university level via the Internet in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation; providing a website via a global computer network with educational information in the academic fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation for the purposes of academic study; providing non-downloadable educational electronic publications in the nature of electronic magazines and articles in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation via the Internet; providing college sport exhibition events and recreation programs, namely, athletic competitions; providing dramatic and musical entertainment events, including live and pre-recorded performances, namely, live plays and musical performances, and screening of pre-recorded films; providing a website featuring information on educational courses, educational and entertainment programs, educational and cultural events, current events news, and recreational and leisure activities in the arts and humanities; educational counseling services to assist students in planning and preparing for further education, and career counseling, namely, providing educational advice concerning options to pursue career opportunities; providing a website featuring information on educational courses and undergraduate and graduate programs in the fields of science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation; providing information on current events relating to science, technology, engineering, quantum science and engineering, robotics, science and technology studies, engineering management, mathematics, business, business management, business intelligence and analytics, enterprise project management, sustainability management, the arts and humanities including history, literature, music, philosophy, social sciences, communications, and visual arts, computer science, cybersecurity, data science, information systems, artificial intelligence, machine learning, marketing innovation and analytics, accounting and analytics, economics, finance, quantitative finance, pre-law, pre-medicine, sports technologies and digital transformation Providing information in the field of computer systems engineering; research, including academic research and scientific research, in the fields of science, technology, engineering, quantum science and engineering, robotics, science and new technology feasibility studies, mathematics, computer enterprise project management, computer science, cybersecurity, data science, computer information systems, and artificial intelligence and machine learning Licensing of technology, namely, licensing of intellectual property

Abrégé

The described invention provides a ureteral stent device comprising a tubular structure comprising a proximal end and a distal end. The proximal end comprises a magnet, a magnetic tip, a magnetic coating, a magnetic metal, or a magnetic alloy. The distal end comprises a tapered tip and can form any one of a J-curl, a j-shape, or a pigtail loop for securing the distal end in a kidney. The proximal end is not secured in the bladder and terminates in the ureter.

Classes IPC  ?

• A61F 2/04 - Éléments ou organes creux ou tubulaires, p. ex. vessies, trachées, bronches ou voies biliaires
• A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes

Abrégé

When one looks at a face, one cannot help but ‘read’ it: in the blink of an eye, people form reliable impressions of both transient psychological states (e.g., happiness) and stable character traits (e.g., trustworthiness). Such impressions are irresistible, formed with high levels of consensus, and important for social decisions. Disclosed herein is a large-scale data-driven methodology that allows for the easy manipulation of social trait information in hyper-realistic face images. For example, a given face image could be made to look more or less trustworthy by moving a simple slider. Further, this method can not only generate faces, but can ‘read’ faces as well, providing confidence estimates of different social traits for any arbitrary image. The disclosed approach is both fast and accurate, and represents a paradigm shift in facial photo manipulation.

Classes IPC  ?

• G06V 40/16 - Visages humains, p. ex. parties du visage, croquis ou expressions
• G06N 3/04 - Architecture, p. ex. topologie d'interconnexion
• G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
• G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux

Abrégé

Three artificial intelligence (AI) linguistic processing architectures are proposed for early detection of Alzheimer's Disease based entirely on a patient's language abilities. Three C-Attention network architectures are presented: one that uses only PoS features, one that uses only the latent features (e.g., language embeddings) and a unified architecture, which uses both features.

Classes IPC  ?

• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
• G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G10L 25/66 - Techniques d'analyse de la parole ou de la voix qui ne se limitent pas à un seul des groupes spécialement adaptées pour un usage particulier pour comparaison ou différentiation pour extraire des paramètres en rapport avec l’état de santé
• G06N 3/02 - Réseaux neuronaux

Abrégé

Compounds according to Formula 1 are capable of inhibiting a RAS protein form.

Classes IPC  ?

• C07D 403/14 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant au moins trois hétérocycles
• C07D 471/10 - Systèmes condensés en spiro
• C07D 491/107 - Systèmes condensés en spiro avec un seul atome d'oxygène comme hétéro-atome du cycle contenant de l'oxygène
• C07D 495/10 - Systèmes condensés en spiro
• C07D 495/20 - Systèmes condensés en spiro
• C07D 498/10 - Systèmes condensés en spiro
• C07D 498/20 - Systèmes condensés en spiro
• A61P 35/00 - Agents anticancéreux
• A61K 31/527 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en spiro
• A61K 31/5386 - 1,4-Oxazines, p. ex. morpholine condensées en spiro ou formant une partie de systèmes cycliques pontés

Abrégé

The present invention relates generally to the manufacture of conductive scaffolds of micro and/or nanofibers with the help of different printing techniques (e.g., near-field electrostatic printing, inkjet printing), such scaffolds enabling the formation of two-dimensional (2D) or three-dimensional (3D) neural networks to mimic the native counterparts. Applications of such patterned conductive scaffolds include, but are not limited to, an engineered conduit for guiding the differentiation and outgrowth of neural cells in peripheral nerve damage or in large-volume spinal cord injury under the electrical stimulation. Meanwhile, the scaffolds could also locally deliver various biomolecules in conjunction with electrical stimulation for facilitated nervous system regeneration.

Classes IPC  ?

• A61N 1/20 - Application de courants électriques par électrodes de contact courants continus ininterrompus
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps

Abrégé

Methods for the development and integration of multiple apparatuses and methods for achieving administration of stem cell therapies include precision manufacturing of tissue scaffolds and/or bioreactor substrates. The nano/microscale fiber material extrusion typifying the electrospinning process is married with the fiber alignment and layering characteristic of an additive manufacturing process. The method generates porous fibrous 3-D meshes with precision controlled structures from biopolymer melts and solutions and gels, blends, and suspensions with and without cells. A method of tracking the migration histories and shapes of stem cells on scaffold surfaces relies on immunofluorescent imaging and automated algorithms based on machine learning. The combination of the precision manufacturing method and the method of cell tracking and cell shape statistics, along with understanding of the intimate relationship between the cell shape/phenotype and scaffold architecture leads to an integrated method for cultivating and harvesting cells having desired phenotypes.

Classes IPC  ?

• C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
• A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
• B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
• A61L 27/38 - Cellules animales
• B33Y 10/00 - Procédés de fabrication additive
• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux

Abrégé

A method for producing doped, van der Walls ferromagnetic materials is disclosed. Such materials can take the form of monolayer iron-doped transition metal dichalcogenides. Such materials are useful for the manufacture of semiconductors, as high curie temperatures are achieved (i.e., those exceeding room temperature), which allows for the preservation of useful ferromagnetic and semiconducting properties across a wider range of conditions.

Classes IPC  ?

• H01L 43/08 - Résistances commandées par un champ magnétique
• C23C 16/30 - Dépôt de composés, de mélanges ou de solutions solides, p. ex. borures, carbures, nitrures
• H01L 43/10 - Emploi de matériaux spécifiés
• H01L 43/12 - Procédés ou appareils spécialement adaptés à la fabrication ou le traitement de ces dispositifs ou de leurs parties constitutives

Abrégé

A method for calculating camera poses and dense scene structure via probabilistic dense indirect visual odometry methods is disclosed. It may be used in various video analysis applications. Through use of a probabilistic model relating to the dependencies among camera movement, scene geometry and the input optical estimates, a generalized expectation maximization inference framework may be employed. The inference is build around an empirically validated error model for observation.

Classes IPC  ?

• G06T 7/77 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés statistiques

Abrégé

A sensor apparatus for footwear includes at least one pair of light sources and at least one pair of light receivers, each light receiver being positioned and configured to receive light emitted from a respective one of the light sources. A pair of movable curtains functions to adjust the amount of light received by the pair of light receivers. The curtains are movable conjointly such that the amount of light received by one of the light receivers is inversely proportional to the amount of light received by the other light receiver.

Classes IPC  ?

• G01L 5/166 - Appareils ou procédés pour la mesure des forces, du travail, de la puissance mécanique ou du couple, spécialement adaptés à des fins spécifiques pour la mesure de plusieurs composantes de la force en utilisant des moyens photoélectriques
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G01D 5/34 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensibleMoyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminéTransducteurs non spécialement adaptés à une variable particulière utilisant des moyens optiques, c.-à-d. utilisant de la lumière infrarouge, visible ou ultraviolette avec atténuation ou obturation complète ou partielle des rayons lumineux les rayons lumineux étant détectés par des cellules photo-électriques

Abrégé

A method for creating oil-filled porous anodic oxide coatings for metallic surfaces is disclosed. The coating has anti-corrosion and omniphobic properties to resist both underwater and atmospheric conditions. To realize oil-impregnated three-dimensional bottle-shaped pores in the oxide layer in anodizing aluminum, the following steps may be taken. First, the target surface may be cleaned and electropolished. Then, a first anodizing step at a lower voltage is applied to create relatively small-diameter pores in the entrance (i.e., top) region of the oxide layer, followed by a second anodizing step at a higher voltage to subsequently create larger- diameter pores in the base (i.e., bottom) region of the oxide layer. Pore widening follows to enlarge the overall pore diameters. To fill the porous coating with an oil, a solvent exchange method may be utilized.

Classes IPC  ?

• C25D 11/12 - Anodisation en plusieurs étapes, p. ex. dans différents bains
• C25D 11/24 - Post-traitement chimique

Abrégé

An optical computation system includes a light source configured to produce a pump beam, an optical modulator configured to modulate the pump beam based on the modulation mask to generate a modulated beam, a non-linear medium configured to convert a portion of the modulated beam to a second harmonic (SH) beam and to produce an output including the SH beam and an unconverted portion of the pump beam, and a dichroic mirror configured to receive the output of the non-linear medium and to decouple the SH beam and the unconverted portion of the pump beam, a detector configured to detect a first optical power of the unconverted portion of the pump beam and to detect a second optical power of the SH beam, and a controller configured to generate an updated modulation mask based on the first and second optical powers for transmission to the optical modulator.

Classes IPC  ?

• G06E 1/02 - Dispositions pour traiter exclusivement des données numériques agissant sur l'ordre ou le contenu des données maniées
• G06N 5/00 - Agencements informatiques utilisant des modèles fondés sur la connaissance
• G06N 7/00 - Agencements informatiques fondés sur des modèles mathématiques spécifiques

Abrégé

An electro-optic modulation structure (110), a method for fabrication of the electro-optic modulation structure, and a method of optical modulation derived from an electro-optic modulation structure with low voltage of operation are disclosed. The low voltage operation of the electro-optic modulator is realized by designed electro-optic modulation structures that include the light confining waveguide (114), overclad layer (120) and modulating electrode structure (116) for applying modulation voltages that are directed towards a low voltage operation of the electro-optic modulation (110) device upon consideration of optimal optical loss.

Classes IPC  ?

• G02F 1/00 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire
• G02B 27/28 - Systèmes ou appareils optiques non prévus dans aucun des groupes , pour polariser
• B82Y 20/00 - Nano-optique, p. ex. optique quantique ou cristaux photoniques
• G02F 1/37 - Optique non linéaire pour la génération de l'harmonique deux
• G02F 1/1343 - Électrodes
• G02F 1/31 - Dispositifs de déflexion numérique
• G02B 5/30 - Éléments polarisants

Abrégé

A method for creating oil-filled porous anodic oxide coatings for stainless steel is disclosed. The coating has anti-corrosion and omniphobic properties to resist both atmospheric conditions, or other conditions with exposure to vapor, and wet conditions, in which the coating is exposed to and/or immersed in liquid. The anodic oxide coating of the present invention can be made by the steps of cleaning and/or electropolishing a steel substrate, applying anodic oxidation to the steel substrate, washing the steel substrate in an organic solvent, and annealing the substrate at high temperature. To fill the porous coating with an oil, a solvent exchange method may be applied.

Classes IPC  ?

• C09D 5/00 - Compositions de revêtement, p. ex. peintures, vernis ou vernis-laques, caractérisées par leur nature physique ou par les effets produitsApprêts en pâte
• C25D 11/14 - Production de couches colorées en totalité

Abrégé

Compounds useful in the treatment of various cancers and in inhibiting ERK protein forms are represented by Formula 1: (I) In Formula 1, R1is hydrogen or methyl. R2is hydrogen, an unsubstituted alkyl group, a haloalkyl group, a hydroxy-methyl group, or a halogen substituted hydroxy-methyl group. R3is a substituted or unsubstituted tert-butyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted heteroaryl group. Each R4 is independently a halogen, an unsubstituted alkyl group, a haloalkyl group, an unsubstituted alkoxy group, or a haloalkoxy group. And n is 0 to 9.

Classes IPC  ?

• A61P 35/00 - Agents anticancéreux
• C07D 495/04 - Systèmes condensés en ortho
• A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
• A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole

Abrégé

A scaffold has a spiral configuration and gradient porosity designed to facilitate the healing of bone injuries. To make the scaffold, a sheet of polymeric material or the like is rolled into a spiral shape. In one embodiment, the resulting scaffold has an outer porous layer with high porosity, and a comparatively less porous inner layer in order to facilitate vascularization and promote recovery. The pores can be filled with a degradable polymer and/or growth factors, bioactive molecules, bactericidal drugs and/or other compositions to further promote recovery.

Classes IPC  ?

• A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 27/56 - Matériaux poreux ou cellulaires
• A61L 27/10 - Céramiques ou verres
• A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
• B33Y 80/00 - Produits obtenus par fabrication additive
• A61F 2/28 - Os

Abrégé

A microtextured artificial cornea made of pHEMA hydrogel and an associated manufacturing method are disclosed. The artificial cornea has two sides, each of which has an associated microstructure. In an embodiment, microlines can be provided on an anterior side, and a posterior side can have micropores. Both the geometry of the microstructures and their dimensions can be customized for an individual patient. The geometry of the artificial cornea itself and its dimensions can also be customized as such. In addition, the lifetime of the artificial cornea can be significantly enhanced by adding co-polymer(s) into the hydrogel to strengthen its mechanical properties. Patient recovery can be aided by adding peptides into the artificial cornea surfaces to improve cell growth post-operation.

Classes IPC  ?

• A61L 27/16 - Matériaux macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61F 2/14 - Parties d'yeux, p. ex. cristallins ou implants de cornéeYeux artificiels
• A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
• A61L 27/26 - Mélanges de matériaux macromoléculaires

Abrégé

A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment.

Classes IPC  ?

• H04L 67/306 - Profils des utilisateurs
• H04W 4/02 - Services utilisant des informations de localisation
• H04W 4/029 - Services de gestion ou de suivi basés sur la localisation
• H04W 4/30 - Services spécialement adaptés à des environnements, à des situations ou à des fins spécifiques
• H04W 88/08 - Dispositifs formant point d'accès
• H04W 84/12 - Réseaux locaux sans fil [WLAN Wireless Local Area Network]
• H04W 4/33 - Services spécialement adaptés à des environnements, à des situations ou à des fins spécifiques pour les environnements intérieurs, p. ex. les bâtiments

Abrégé

This invention relates to a neural scaffold (10) for use as an artificial nerve graft to bridge nerve injury gaps and promote peripheral nerve regeneration and a method to make same. The scaffold has microchannels (16) as a micro-feature and nanofibers (18) as a nano-feature. The nanofibers (18) function to aid Schwann cell migration, while the microchannels (16) promote neurite extension and are conducive to formation of myelinated axons. The microchannels (16) extend in a direction generally along a longitudinal axis of the scaffold (10) in the desired direction for cell growth.

Classes IPC  ?

• A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 27/20 - Polysaccharides
• A61L 27/24 - Collagène
• A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels

Abrégé

The present disclosure relates to a generally-applicable measurement technique based on coherent quantum enhancement effects and provides embodiments with nonlinear optics. The technique utilizes parametric nonlinear processes where the information-carrying electromagnetic quanta in a number of electromagnetic modes are converted phase coherently to signature quanta in a single mode or a few modes. The phase coherence means that while the quanta before conversion may have unequal or uncertain phase values across the modes, the signature quanta converted from those different modes have the (near) uniform phase. This can lead to significant increase in the signal to noise ratio in detecting weak signal buried in strong background noise. Applications can be found in remote sensing, ranging, biological imaging, field imaging, target detection and identification, covert communications, and other fields that can benefit from improved signal to noise ratios by using the phase coherent effect.

Classes IPC  ?

• G01C 3/08 - Utilisation de détecteurs électriques de radiations
• G01S 17/06 - Systèmes déterminant les données relatives à la position d'une cible
• H04B 10/70 - Communications quantiques photoniques
• G01S 17/10 - Systèmes déterminant les données relatives à la position d'une cible pour mesurer la distance uniquement utilisant la transmission d'ondes à modulation d'impulsion interrompues

Abrégé

A device for generation of genuine random numbers, uses quantum stochastic processes in optical parametric nonlinear media. The dimensionality of the random numbers is varied from 2 to over 100,000. Their statistical properties, including the correlation function amongst random numbers, are tailored using linear and nonlinear optical circuits following the parametric nonlinear media. Both the generation and manipulation of random numbers are integrated on a single nanophotonics chip. By incorporating optoelectric effects, fast streams of random numbers are created in custom statistical properties, which are updated or reconfigured in real time, such as at 10 GHz speed. The unpredictability of the random numbers is quantifying by evaluating their min-entropy. The genuineness of quantum random numbers is tested using both statistical tools and independently verified by measuring the quantum entanglement between the photons in real time.

Classes IPC  ?

• G06F 7/58 - Générateurs de nombres aléatoires ou pseudo-aléatoires
• H04L 9/08 - Répartition de clés

Abrégé

The present invention relates to methods for secure computation and/or communication. Entangled photons (118) are generated such that each participating party receives a series of optical pulses. Each party has private information (110, 112) which are never transmitted through public or private communication channels. Instead, each party converts their respective private information (110, 112) into measurement bases via an encryption process (114, 116) which are then applied to the entangled photons (118). After the measurement process, e.g., quantum frequency conversion (122, 124), reference indices are announced (124, 126) so that computation can be performed (128) without revealing the private information directly or indirectly.

Classes IPC  ?

• H04L 9/08 - Répartition de clés
• H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système

Abrégé

Approaches, apparatuses and methods for LIDAR applications based on mode-selective frequency conversion are disclosed. In one embodiment, a pulse generation unit includes a mode-locked fiber laser and optical fiber bandpass filters. In the second embodiment, a LIDAR transceiver unit based on a simple, bidirectional monostatic coaxial arrangement using off-the-shelf telecom-grade optical components includes optical fiber, fiber collimator, optical fiber circulator, optical fiber isolator and wavelength combiner. A frequency conversion detection system with single photon sensitivity includes a nonlinear optical material for frequency conversion, coupled with optimized pump pulses for efficient conversion and noise rejection, optical band pass filters for noise rejection and a single photon detection system for detecting the converted signal.

Classes IPC  ?

• G01C 3/08 - Utilisation de détecteurs électriques de radiations
• G01S 7/481 - Caractéristiques de structure, p. ex. agencements d'éléments optiques
• G01S 7/484 - Émetteurs
• G01S 17/89 - Systèmes lidar, spécialement adaptés pour des applications spécifiques pour la cartographie ou l'imagerie
• G02B 26/08 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander la direction de la lumière
• G02B 27/30 - Collimateurs
• G02F 1/37 - Optique non linéaire pour la génération de l'harmonique deux

Abrégé

Disclosed is a system and method for remote sensing, surface profiling, object identification, and aiming based on two-photon population inversion and subsequent photon backscattering enhanced by superradiance using two co-propagating pump waves. The present disclosure enables efficient and highly-directional photon backscattering by generating the pump waves in properly pulsed time-frequency modes, proper spatial modes, with proper group-velocity difference in air. The pump waves are relatively delayed in a tunable pulse delay device and launched to free space along a desirable direction using a laser-pointing device. When the pump waves overlap in air, signal photons will be created through two-photon driven superradiant backscattering if target gas molecules are present. The backscattered signal photons propagate back, picked using optical filters, and detected. By scanning the relative delay and the launching direction while the signal photons are detected, three-dimensional information of target objects is acquired remotely.

Classes IPC  ?

• H01S 3/094 - Procédés ou appareils pour l'excitation, p. ex. pompage utilisant le pompage optique par de la lumière cohérente
• G02B 27/09 - Mise en forme du faisceau, p. ex. changement de la section transversale, non prévue ailleurs
• H01S 3/11 - Blocage de modesCommutation-QAutres techniques d'impulsions géantes, p. ex. vidange de cavité
• H01S 3/00 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet
• G01S 7/48 - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe
• G01S 17/00 - Systèmes utilisant la réflexion ou la reradiation d'ondes électromagnétiques autres que les ondes radio, p. ex. systèmes lidar
• G01S 17/95 - Systèmes lidar, spécialement adaptés pour des applications spécifiques pour la météorologie
• G01S 17/88 - Systèmes lidar, spécialement adaptés pour des applications spécifiques
• H01S 3/30 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet utilisant des effets de diffusion, p. ex. l'effet Brillouin ou Raman stimulé
• H01S 3/067 - Lasers à fibre optique
• H01S 3/16 - Matériaux solides

Abrégé

When one looks at a face, one cannot help but ‘read’ it: in the blink of an eye, people form reliable impressions of both transient psychological states (e.g., happiness) and stable character traits (e.g., trustworthiness). Such impressions are irresistible, formed with high levels of consensus, and important for social decisions. Disclosed herein is a large-scale data-driven methodology that allows for the easy manipulation of social trait information in hyper-realistic face images. For example, a given face image could be made to look more or less trustworthy by moving a simple slider. Further, this method can not only generate faces, but can ‘read’ faces as well, providing confidence estimates of different social traits for any arbitrary image. The disclosed approach is both fast and accurate, and represents a paradigm shift in facial photo manipulation.

Classes IPC  ?

• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
• G06N 3/04 - Architecture, p. ex. topologie d'interconnexion

Abrégé

Flexible air-breathing microscale fuel cells are produced using ion exchange polymer membranes without silicon substrates or other rigid components. The microscale fuel cells provide long-life energy supply sources in portable electronics due to reduced volume, high energy density, and low cost. More particularly, the microscale fuel cell has a direct hydrogen flow-through porous anode electrode with a pair of air-breathing cathodes.

Classes IPC  ?

• H01M 8/1004 - Éléments à combustible avec électrolytes solides caractérisés par les ensembles membrane-électrodes [MEA]
• H01M 4/86 - Électrodes inertes ayant une activité catalytique, p. ex. pour piles à combustible
• H01M 8/00 - Éléments à combustibleLeur fabrication
• H01M 8/0271 - Moyens d’étanchéité ou de support autour des électrodes, des matrices ou des membranes
• H01M 8/1007 - Éléments à combustible avec électrolytes solides avec les deux réactifs gazeux ou vaporisés
• H01M 8/1018 - Matériaux d’électrolyte polymère
• H01M 8/241 - Groupement d'éléments à combustible, p. ex. empilement d'éléments à combustible avec électrolytes solides ou supportés par une matrice
• H01M 8/10 - Éléments à combustible avec électrolytes solides
• H01M 8/1039 - Matériaux d’électrolyte polymère halogénés, p. ex. des fluorures de polyvinylidène sulfonés
• H01M 8/1067 - Matériaux d’électrolyte polymère caractérisés par leurs propriétés physiques, p. ex. la porosité, la conductivité ionique ou l’épaisseur

Abrégé

A method of localizing brain regions for the purpose of guiding placement of electrodes and related implants is disclosed. The inventive method involves effecting a pulse in a patient's brain, temporally aligning readings taken from an electrode at various depths, measuring local field potentials at each depth during interstimulus intervals, performing a coherence analysis comparing the local field potential measurements of the different depths, and determining a corresponding brain region for the depths compared.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• A61N 1/08 - Aménagements ou circuits de surveillance, de protection, de commande ou d'indication
• A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
• A61B 5/377 - Électroencéphalographie [EEG] utilisant des réponses provoquées
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

The described invention provides an ex vivo dynamic multiple myeloma (MM) cancer niche contained in a pumpless perfusion culture device. The dynamic MM cancer niche includes (a) a three-dimensional tissue construct containing a dynamic ex vivo bone marrow (BM) niche, which contains a mineralized bone-like tissue containing viable osteoblasts self- organized into cohesive multiple cell layers and an extracellular matrix secreted by the viable adherent osteoblasts; and a microenvironment dynamically perfused by nutrients and dissolved gas molecules; and (b) human myeloma cells seeded from a biospecimen composition comprising mononuclear cells and the multiple myeloma cells. The human myeloma cells are in contact with osteoblasts of the BM niche, and the viability of the human myeloma cells is maintained by the MM cancer niche.

Classes IPC  ?

• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• C12N 5/07 - Cellules animales ou tissus animaux
• C12N 5/09 - Cellules tumorales

Abrégé

An adapter for use in conjunction with a tracheostomy tube and/or its attachments is disclosed. It is adapted to complement conventional tracheostomy tubes and monitor and measure an assortment of breathing parameters, through one or more sensors, such as thermistors, microphones and the like. In order to evaluate whether there is a problem in the patient's airway (e.g., an obstruction), the data from the sensors is compared. By incorporating an alarm system as part of, or in conjunction with, the present invention, healthcare providers can be better able to quickly react to potential problems in the patient's airway.

Classes IPC  ?

• A61M 16/00 - Dispositifs pour agir sur le système respiratoire des patients par un traitement au gaz, p. ex. ventilateursTubes trachéaux
• A61M 16/04 - Tubes trachéaux

Abrégé

A magnetically coupled ball drive system for actuation of spherical surfaces and wheels is disclosed. An internal support structure interacts with exterior drive wheels magnetically to produce rotational motion. A related improvement involving reduction of slip due to insufficient traction is also presented to establish a design for a more robust and versatile device that can be used in robotics or for producing vehicle locomotion.

Classes IPC  ?

• H02K 49/10 - Embrayages dynamo-électriquesFreins dynamo-électriques du type à aimant permanent
• B60B 19/00 - Roues non prévues ailleurs ou ayant des caractéristiques précisées dans l'un des sous-groupes du présent groupe
• B60B 19/14 - Roues en forme de sphères
• B62D 11/00 - Direction pour roues non orientablesDirection pour véhicules à chenilles ou à dispositifs similaires
• B62D 11/04 - Direction pour roues non orientablesDirection pour véhicules à chenilles ou à dispositifs similaires par entraînement différencié des éléments en contact avec le sol sur les côtés opposés du véhicule par sources d'énergie séparées

Abrégé

Flexible and stretchable supercapacitors are made using carbon nanostructures produced by providing a first composite structure which includes a temporary substrate and an array of carbon nanotubes arranged in a stack on a surface of the temporary substrate such that the stack of carbon nanotubes is oriented generally perpendicular to the surface of the temporary substrate, which may include silicon dioxide. The stack of carbon nanotubes is transferred from the temporary substrate to another substrate, which includes a curable polymer, thereby forming another composite structure comprising the stack of carbon nanotubes and the cured polymer.

Classes IPC  ?

• B32B 9/00 - Produits stratifiés composés essentiellement d'une substance particulière non couverte par les groupes
• C01B 32/162 - Préparation caractérisée par les catalyseurs
• C08J 5/12 - Fixation d'un matériau macromoléculaire préformé au même matériau ou à un autre matériau compact, tel que du métal, du verre, du cuir, p. ex. en utilisant des adhésifs
• H01G 11/36 - Nanostructures, p. ex. nanofibres, nanotubes ou fullerènes
• H01G 11/56 - Électrolytes solides, p. ex. gelsAdditifs pour ceux-ci
• H01G 11/58 - Électrolytes liquides
• H01G 11/86 - Procédés de fabrication de condensateurs hybrides ou EDL ou de leurs composants spécialement adaptés pour les électrodes
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites

Abrégé

An artificial cornea and an associated manufacturing method are disclosed. The artificial cornea has two sides, each of which has an associated microstructure. In an embodiment, microlines can be provided on an anterior side, and a posterior side can have micropores. Both the geometry of the microstructures and their dimensions can be customized for an individual patient. The geometry of the artificial cornea itself and its dimensions can also be customized as such. In addition, the lifetime of the artificial cornea can be significantly enhanced by adding co-polymer(s) into the hydrogel to strengthen its mechanical properties. Patient recovery can be aided by adding peptides into the artificial cornea surfaces to improve cell growth post-operation.

Classes IPC  ?

• A61F 2/14 - Parties d'yeux, p. ex. cristallins ou implants de cornéeYeux artificiels
• A61L 27/02 - Matériaux inorganiques
• A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
• A61L 27/52 - Hydrogels ou hydrocolloïdes
• A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents

Abrégé

Smart membranes (14) are integrated into a small, unmanned surface vessel (20) to enable the efficient, automated cleanup of oil spills. Such a vessel (20) has the potential to provide a low-cost, modular solution for day-to-day oil-spill cleanup operations, especially in confined aquatic areas, such as under piers and in the small spaces between marine vessels and piers. The smart membranes (14) are provided on the surface of a conveyor belt (34) that circulates the membranes (14) through the surrounding body of water (10) for oil collection, as well as through an internal reduction chamber (22) of the vessel (20) for oil release. The smart membranes (14) are adapted to attract and repel oil (12) in response to low-voltage commands applied across the conveyor belt (34), using a process that is repeatable for a number of cycles, offering high efficiency and long durability (FIG. 5).

Classes IPC  ?

• C02F 1/40 - Dispositifs pour séparer ou enlever les substances grasses ou huileuses, ou les matières flottantes similaires
• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
• C02F 101/32 - Hydrocarbures, p. ex. huiles
• C02F 103/00 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter

Abrégé

Filter media for treating contaminated water is produced from aluminum-based water treatment residuals (Al-WTR) commonly produced as a byproduct of water treatment plants. By processing the residuals into small granules, a superior green sorbent product is obtained with the functionality to adsorb contaminants, such as metals and certain nutrients in water. Biopolymers can be incorporated into the filter media to further enhance functionality and hydraulic characters.

Classes IPC  ?

• B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
• B01D 39/20 - Autres substances filtrantes autoportantes en substance inorganique, p. ex. papier d'amiante ou substance filtrante métallique faite de fils métalliques non-tissés
• B01D 39/16 - Autres substances filtrantes autoportantes en substance organique, p. ex. fibres synthétiques
• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• B01J 20/24 - Composés macromoléculaires d'origine naturelle, p. ex. acides humiques ou leurs dérivés
• B01J 20/30 - Procédés de préparation, de régénération ou de réactivation

Abrégé

A system may provide blockchain-based storage node control for unified proof-of-storage interaction for off-chain data chunk storage. The system may include verification circuitry that may provide a challenge to a storage node to audit the storage status of a data chunk. The verification circuitry may obtain identities for the storage node and data chunk based on blockchain records. The verification circuitry may obtain a challenge answer from the storage node in response. The verification circuitry may analyze the challenge answer in view of a challenge key to confirm whether the storage node has possession of the data chunk. When the storage node has possession of the data chunk chain circuitry may add a verification record to the blockchain.

Classes IPC  ?

• H04L 9/06 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité l'appareil de chiffrement utilisant des registres à décalage ou des mémoires pour le codage par blocs, p. ex. système DES
• G06F 21/60 - Protection de données
• H04L 9/14 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité utilisant plusieurs clés ou algorithmes
• H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
• G06F 21/64 - Protection de l’intégrité des données, p. ex. par sommes de contrôle, certificats ou signatures
• H04L 9/00 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité

Abrégé

Process and apparatus are disclosed for capturing and converting an ozone-depleting alkyl halide fumigant from a fumigant/air mixed stream (14) by absorbing it into a metal hydroxide-alcohol buffer solution (26) in an absorber/scrubber (12) to produce a fumigant-free air stream. The captured alkyl halide in aqueous alcohol solution can actively react with the metal hydroxide in alcohol solution to produce a value-added product, such as a precipitate metal halide, and another alcohol that further enhances absorption. The absorbing solution is well-mixed with make-up alcohol and alkali streams to maintain the concentration of the metal hydroxide in the desired buffer solution range. The solid precipitate metal halide is separated from the liquid stream, and the metal hydroxide-containing mixed alcohol stream is recycled to the absorber/scrubber (12).

Classes IPC  ?

• B01D 53/18 - Unités d'absorptionDistributeurs de liquides
• B01D 53/70 - Composés halogénés organiques
• B01D 53/78 - Procédés en phase liquide avec un contact gaz-liquide

Abrégé

Embodiments of the invention include a system and method for detecting wood-boring species of insects in a structure (16), involving one or more primary (14) and reference (18) sensors and a signal conditioning and acquisition device (22) capable of being coupled to the sensors (14, 18). The system (10) also includes a processor (24) capable of being coupled to a non-transitory, computer-readable storage medium that includes program logic for execution by the processor (24). The program logic includes a logic module that receives signals originating from the sensors (14, 18) and discriminates between noise generated by any wood boring species in the structure and extraneous noise unrelated to the wood boring species of insects. The extraction of signal features based on pulse duration, signal spectra and signal envelope spectra can be used for insect pulse discrimination. A sound-suppressing sensor assembly (12) can be weighted to enhance the coupling of the primary sensor (14) with the structure (16) being tested.

Classes IPC  ?

• G01N 29/44 - Traitement du signal de réponse détecté
• G01H 11/08 - Mesure des vibrations mécaniques ou des ondes ultrasonores, sonores ou infrasonores par détection des changements dans les propriétés électriques ou magnétiques par des moyens électriques utilisant des dispositifs piézo-électriques

Abrégé

The described invention provides a ureteral stent device comprising a tubular structure comprising a proximal end and a distal end. The proximal end comprises a magnet, a magnetic tip, a magnetic coating, a magnetic metal, or a magnetic alloy. The distal end comprises a tapered tip and can form any one of a J-curl, a j- shape, or a pigtail loop for securing the distal end in a kidney. The proximal end is not secured in the bladder and terminates in the ureter.

Classes IPC  ?

• A61F 2/04 - Éléments ou organes creux ou tubulaires, p. ex. vessies, trachées, bronches ou voies biliaires
• A61F 2/06 - Vaisseaux sanguins
• A61M 25/01 - Introduction, guidage, avance, mise en place ou maintien en position des cathéters
• A61M 25/04 - Dispositifs de maintien en position, p. ex. sur le corps à l'intérieur du corps, p. ex. expansibles
• A61M 25/18 - Raccord des cathéters ou des sondes aux embouts
• A61M 27/00 - Appareillage pour drainage des blessures

Abrégé

Disclosed is a system and method for remote sensing, surface profiling, object identification, and aiming based on two-photon population inversion and subsequent photon backscattering enhanced by superradiance using two co-propagating pump waves. The present disclosure enables efficient and highly-directional photon backscattering by generating the pump waves in properly pulsed time-frequency modes, proper spatial modes, with proper group-velocity difference in air. The pump waves are relatively delayed in a tunable pulse delay device and launched to free space along a desirable direction using a laser-pointing device. When the pump waves overlap in air, signal photons will be created through two-photon driven superradiant backscattering if target gas molecules are present. The backscattered signal photons propagate back, picked using optical filters, and detected. By scanning the relative delay and the launching direction while the signal photons are detected, three-dimensional information of target objects is acquired remotely.

Classes IPC  ?

• H01S 3/094 - Procédés ou appareils pour l'excitation, p. ex. pompage utilisant le pompage optique par de la lumière cohérente
• G02B 27/09 - Mise en forme du faisceau, p. ex. changement de la section transversale, non prévue ailleurs
• H01S 3/11 - Blocage de modesCommutation-QAutres techniques d'impulsions géantes, p. ex. vidange de cavité
• H01S 3/00 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet
• G01S 7/48 - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe
• G01S 17/00 - Systèmes utilisant la réflexion ou la reradiation d'ondes électromagnétiques autres que les ondes radio, p. ex. systèmes lidar
• G01S 17/95 - Systèmes lidar, spécialement adaptés pour des applications spécifiques pour la météorologie
• G01S 17/88 - Systèmes lidar, spécialement adaptés pour des applications spécifiques
• H01S 3/30 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet utilisant des effets de diffusion, p. ex. l'effet Brillouin ou Raman stimulé
• H01S 3/067 - Lasers à fibre optique
• H01S 3/16 - Matériaux solides

Abrégé

The described invention provides an ex vivo dynamic multiple myeloma cancer niche contained in a pumpless perfusion culture device. The dynamic multiple myeloma cancer niche includes (a) a three-dimensional tissue construct containing a dynamic ex vivo bone marrow niche, which contains a mineralized bone-like tissue containing viable osteoblasts self-organized into cohesive multiple cell layers and an extracellular matrix secreted by the viable adherent osteoblasts; and a microenvironment dynamically perfused by nutrients and dissolved gas molecules; and (b) human myeloma cells seeded from a biospecimen composition comprising mononuclear cells and the multiple myeloma cells. The human myeloma cells are in contact with osteoblasts of the bone marrow niche, and the viability of the human myeloma cells is maintained by the multiple myeloma cancer niche.

Classes IPC  ?

• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
• C12N 5/078 - Cellules du sang ou du système immunitaire
• C12N 5/09 - Cellules tumorales
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires

Abrégé

A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment.

Classes IPC  ?

• H04L 29/08 - Procédure de commande de la transmission, p.ex. procédure de commande du niveau de la liaison
• H04W 4/02 - Services utilisant des informations de localisation
• H04W 4/029 - Services de gestion ou de suivi basés sur la localisation
• H04W 4/30 - Services spécialement adaptés à des environnements, à des situations ou à des fins spécifiques
• H04W 88/08 - Dispositifs formant point d'accès
• H04W 84/12 - Réseaux locaux sans fil [WLAN Wireless Local Area Network]
• H04W 4/33 - Services spécialement adaptés à des environnements, à des situations ou à des fins spécifiques pour les environnements intérieurs, p. ex. les bâtiments

Abrégé

Embodiments of the invention include methods for producing polymer gels useful in the fabrication of organic cells. The method includes mixing poly(3-hexylthiophene) with phenyl-C61 butyric acid methyl ester and solvent to form a first solution, where the poly(3-hexylthiophene) includes at least some regioregular poly(3-hexylthiophene). The first solution is then cooled to a specified temperature to induce gelation to form an at least partially gelled solution that can be deposited onto a surface to form a coated surface. At least one or more steps of the method can occur as an extrusion process carried out in a twin-screw or single-screw extruder.

Classes IPC  ?

• B05D 1/26 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces par application de liquides ou d'autres matériaux fluides, à partir d'un orifice en contact ou presque en contact avec la surface
• C09D 5/24 - Peintures électriquement conductrices
• C09D 165/00 - Compositions de revêtement à base de composés macromoléculaires obtenus par des réactions créant une liaison carbone-carbone dans la chaîne principaleCompositions de revêtement à base de dérivés de tels polymères
• H01L 51/42 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement en énergie électrique, soit comme dispositifs de commande de l'énergie électrique par ledit rayonnement
• H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
• C09D 7/20 - Diluants ou solvants