Abrégé

Disclosed is a composition for promoting production of type I collagen. The composition includes Platycodon grandiflorus.

Classes IPC  ?

• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
• A61K 36/346 - Platycodon
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• A61K 125/00 - Parties de plantes contenant des racines, des bulbes, des tubercules ou des rhizomes, ou obtenues à partir de ces éléments

Abrégé

Provided are a spoon tapping device, etc., with which agglomeration of powder or granular material scooped into a spoon can be avoided, thereby enabling the powder or granular material to be dropped, little by little, more reliably than in a case in which the powder or granular material is caused to drop by vibrating the spoon continuously for a predetermined time.　A spoon tapping device (1) comprises a spoon (3) for scooping up powder or granular material, a tapping tool (4) for tapping a portion (3a) of the spoon from above, and a driving apparatus (5) for intermittently driving the tapping tool, wherein: the tapping tool (4) includes an impinging part (41) which impinges upon the portion (3a) of the spoon, and a movable arm (42) to which the impinging part is attached, and which moves such that the impinging part comes into contact with the portion of the spoon; and when the powder or granular material scooped into the spoon is being caused to drop little by little, the driving apparatus (5) moves the movable arm such that the impinging part intermittently impinges upon the portion of the spoon.

Classes IPC  ?

• G01G 13/00 - Appareils de pesée avec remplissage ou vidange automatiques pour peser des quantités données d'un produit
• G01G 13/16 - Moyens pour vidanger automatiquement des récipients de pesée, l'opération étant commandée par le mécanisme de pesée
• G01G 13/24 - Aménagements apportés à un mécanisme de pesée pour commander le remplissage ou la vidange automatique
• G01G 19/56 - Appareils de pesée combinés avec d'autres objets, p. ex. avec de l'ameublement combinés avec des poignées d'outils ou des ustensiles de ménage

Abrégé

Pharmaceutical preparations, Chinese herbal preparations, foods, and other compositions may contain, as an active ingredient, an ephedra extract, an ephedrine-alkaloid-free ephedra extract, or a polymercondensed tannin derived from an ephedra extract. Such compositions may be useful for preventing or treating COVID-19 infection (COVID-19). Such compositions are preferably provided in an orally ingestible form.

Classes IPC  ?

• A61K 36/13 - Coniferophyta (gymnospermes)
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
• A61P 31/14 - Antiviraux pour le traitement des virus ARN

Abrégé

The present invention involves the use of pharmaceutical preparations, Chinese herbal preparations, foods, and other compositions containing, as an active ingredient, an ephedra extract, an ephedrine-alkaloid-free ephedra extract, or a polymer-condensed tannin derived from an ephedra extract, the compositions being for preventing or treating COVID-19 infection (COVID-19). These compositions are preferably provided in an orally ingestible form.

Classes IPC  ?

• A61K 36/17 - Gnetophyta, p. ex. Ephedraceae (famille du camillo du Texas)
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
• A61P 31/14 - Antiviraux pour le traitement des virus ARN

Abrégé

m ratio is a higher value than a reference value.

Classes IPC  ?

• C12Q 1/06 - Détermination quantitative
• C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
• G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
• C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• C12Q 1/24 - Méthodes d'échantillonnage, d'inoculation ou de développement d'un échantillonMéthodes pour isoler physiquement un micro-organisme intact
• C12N 1/20 - BactériesLeurs milieux de culture

Produits et services

Drugs for the treatment of headache; medical analgesic preparations; medicinal syrups; medicinal capsules; drugs to ease constipation; analgesic drugs; extracts from medicinal plants; laxatives; antipyretic agents; fungicides; nerve tranquillizers; light evacuants; bactericides; pastilles for pharmaceutical purposes; pharmaceutical preparations; tablets for pharmaceutical purposes; medicinal ointments; organotherapy preparations; drug capsules; tonic drugs; sedatives; hypnotics; medicines for human purposes; medicinal tablets; ointments; crude drugs; Chinese traditional medicines; medicinal herbs; herbal teas for medicinal purposes; medicinal lotions; pharmaceutical preparations for dermatosis; medical bath preparations; mineral water bath salts for medical purposes; therapeutic preparations for the bath; medicated bath salts; oxygen for bath; medical nutritious foods; air deodorants; insecticides; dental abrasives; medical drugs; medical fumigants; rodenticides; pesticides; herbicides; insect exterminating agents; antiseptic agents (for pharmaceutical preparations); nutritional supplements; traditional Chinese medicines prepared in ready-to-use forms; sliced crude drugs; traditional Chinese medicinal drugs; crude drugs in form of granules; granules extracted from crude drugs; medicinal drinks; medicinal liquors; powdered crude drugs; crude drug extract powders.

Produits et services

Drugs for the treatment of headache; medical analgesic preparations; medicinal syrups; medicinal capsules; drugs to ease constipation; analgesic drugs; extracts from medicinal plants; laxatives; antipyretic agents; fungicides; nerve tranquillizers; light evacuants; bactericides; pastilles for pharmaceutical purposes; pharmaceutical preparations; tablets for pharmaceutical purposes; medicinal ointments; organotherapy preparations; drug capsules; tonic drugs; sedatives; hypnotics; medicines for human purposes; medicinal tablets; ointments; crude drugs; Chinese traditional medicines; medicinal herbs; herbal teas for medicinal purposes; medicinal lotions; pharmaceutical preparations for dermatosis; medical bath preparations; mineral water bath salts for medical purposes; therapeutic preparations for the bath; medicated bath salts; oxygen for bath; medical nutritious foods; air deodorants; insecticides; dental abrasives; medical drugs; medical fumigants; rodenticides; pesticides; herbicides; insect exterminating agents; antiseptic agents (for pharmaceutical preparations); nutritional supplements; traditional Chinese medicines prepared in ready-to-use forms; sliced crude drugs; traditional Chinese medicinal drugs; crude drugs in form of granules; granules extracted from crude drugs; medicinal drinks; medicinal liquors; powdered crude drugs; crude drug extract powders.

Abrégé

The present invention provides a method for determining a dosage of Daikenchuto, a method for predicting the efficacy of Daikenchuto, etc. using an objective index. The method for predicting the efficacy of Daikenchuto in a patient is characterized by comprising step (a) for analyzing the bacterial flora in the intestines of the patient to determine the ratio (Bm/Fm ratio) between the phylum Bacteroidetes and the phylum Firmicutes, and step (b) for determining the efficacy of Daikenchuto in the patient by comparing the Bm/Fm ratio against a criteria that having a Bm/Fm ratio lower than a standard value represents good efficacy of Daikenchuto, whereas having a Bm/Fm ratio higher than the standard value represents poor efficacy of Daikenchuto. Furthermore, the method for determining a dosage of Daikenchuto for a patient is characterized by comprising step (a) for analyzing the bacterial flora in the intestines of the patient to determine the ratio (Bm/Fm ratio) between the phylum Bacteroidetes and the phylum Firmicutes, and step (e) for determining a dosage of Daikenchuto to be administered to the patient by reducing the dosage of Daikenchuto in the case when the Bm/Fm ratio is lower than a standard value, and by increasing the dosage of Daikenchuto to be administered to the patient in the case when the Bm/Fm ratio is higher than the standard value.

Classes IPC  ?

• C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
• C12N 1/20 - BactériesLeurs milieux de culture

Abrégé

Provided are a method of and an apparatus for formulating a multicomponent drug capable of surely making a multicomponent drug meeting criteria for productization with high accuracy into a product. The method and apparatus obtain a chromatogram from an extract or a base of a multicomponent drug, evaluate whether the base meets the criteria for productization based on the obtained chromatogram with high accuracy, and subject the base determined in the high-accuracy evaluating as an accepted one meeting the criteria to dosage form processing, to produce a formulated drug having a given dosage form. The high quality evaluation is realized by performing peak assignment of a target fingerprint obtained from a chromatogram to a reference fingerprint with high accuracy.

Classes IPC  ?

• G06F 19/00 - Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des applications spécifiques (spécialement adaptés à des fonctions spécifiques G06F 17/00;systèmes ou méthodes de traitement de données spécialement adaptés à des fins administratives, commerciales, financières, de gestion, de surveillance ou de prévision G06Q;informatique médicale G16H)
• G01N 30/86 - Analyse des signaux
• G01N 33/15 - Préparations médicinales
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Produits et services

Pharmaceutical, veterinary and sanitary preparations; dietetic substances adapted for medical use, food for babies; plasters, materials for dressings; crude drugs pieces for decoction; crude drugs and medicines; traditional herbal medicine.

Produits et services

Pharmaceutical, veterinary and sanitary preparations; dietetic substances adapted for medical use, food for babies; plasters, materials for dressings; crude drug pieces for decoction; crude drugs and medicines; traditional herbal medicine.

Produits et services

Pharmaceutical, veterinary and sanitary preparations; dietetic substances adapted for medical use, food for babies; plasters, materials for dressings; crude drug pieces for decoction; crude drugs and medicines; traditional herbal medicine.

Abrégé

Provided are a method of and an apparatus for formulating a multicomponent drug capable of surely making a multicomponent drug meeting criteria for productization with high accuracy into a product. The method and apparatus obtain a chromatogram from an extract or a base of a multicomponent drug, evaluate whether the base meets the criteria for productization based on the obtained chromatogram with high accuracy, and subject the base determined in the high-accuracy evaluating as an accepted one meeting the criteria to dosage form processing, to produce a formulated drug having a given dosage-form.

Classes IPC  ?

• G01N 30/86 - Analyse des signaux
• G01N 33/15 - Préparations médicinales
• G16C 20/20 - Identification d’entités moléculaires, de leurs parties ou de compositions chimiques

Abrégé

Provided are a method of and an apparatus for formulating a multicomponent drug capable of surely making a multicomponent drug meeting criteria for productization with high accuracy into a product. The method and apparatus obtain a chromatogram from an extract or a base of a multicomponent drug, evaluate whether the base meets the criteria for productization based on the obtained chromatogram with high accuracy, and subject the base determined in the high-accuracy evaluating as an accepted one meeting the criteria to dosage form processing, to produce a formulated drug having a given dosage form. The high quality evaluation is realized by performing peak assignment of a target fingerprint obtained from a chromatogram to a reference fingerprint with high accuracy.

Classes IPC  ?

• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• G01N 30/86 - Analyse des signaux
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

Provided are a method of and an apparatus for formulating a multicomponent drug capable of surely making a multicomponent drug meeting criteria for productization with high accuracy into a product. The method and apparatus obtain a chromatogram from an extract or a base of a multicomponent drug, evaluate whether the base meets the criteria for productization based on the obtained chromatogram with high accuracy, and subject the base determined in the high-accuracy evaluating as an accepted one meeting the criteria to dosage form processing, to produce a formulated drug having a given dosage-form. The high quality evaluation is realized by using fingerprint area segmentation feature values obtained from a fingerprint formed from a chromatogram and segmented into a plurality of areas.

Classes IPC  ?

• G01N 30/74 - Détecteurs optiques
• G01N 30/86 - Analyse des signaux
• G16C 20/20 - Identification d’entités moléculaires, de leurs parties ou de compositions chimiques
• G05B 15/00 - Systèmes commandés par un calculateur
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes
• G01N 30/02 - Chromatographie sur colonne

Abrégé

Provided are a method of and an apparatus for formulating a multicomponent drug capable of surely making a multicomponent drug meeting criteria for productization with high accuracy into a product. The method and apparatus obtain a chromatogram from an extract or a base of a multicomponent drug, evaluate whether the base meets the criteria for productization based on the obtained chromatogram with high accuracy, and subject the base determined in the high-accuracy evaluating as an accepted one meeting the criteria to dosage form processing, to produce a formulated drug having a given dosage-form. The high-accuracy evaluating is realized by selecting with high accuracy one of reference fingerprints to which peaks of a target fingerprint prepared from the chromatogram are assigned.

Classes IPC  ?

• G01N 30/86 - Analyse des signaux
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes
• G16C 20/20 - Identification d’entités moléculaires, de leurs parties ou de compositions chimiques

Abrégé

Provided is a microorganism detection method which is highly versatile and applicable to both the test for the detection of specified microorganisms and the microbial enumeration test under the same test conditions for Kampo extract preparations and crude drugs containing a variety of antimicrobial substances, is able to effectively reduce the influence of antimicrobial substances in a test sample, and may detect target microorganisms with high precision. This method is a microorganism detection method in a test sample having antimicrobial activity, including a step of preparing a sample liquid containing a test sample having antimicrobial activity and a step of culturing a target microorganism in a culture medium, the method including allowing a (meth)acrylic acid ester-based synthetic adsorbent to act on the sample liquid and/or the culture medium.

Classes IPC  ?

• C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
• C12Q 1/22 - Test des conditions de stérilité
• C12Q 1/06 - Détermination quantitative
• G01N 1/40 - Concentration des échantillons

Abrégé

To provided a technique that makes it possible to overcome problems in Asian Ginseng cultivation, and to cultivate Asian Ginseng in a stable and efficient manner. A method for cultivating Asian Ginseng, characterized in comprising steps for: readying a plurality of non-woven fabric pots shaped so as to be relatively longer in one direction and relatively shorter in another direction in top view, each of the pots having an opening located at a top part; placing cultivation soil in each of the pots and planting Asian Ginseng seedlings along the longitudinal direction of the pots so that the axis of each of the seedlings is inclined; and placing the pots on a multistage rack so that the germination side of the seedlings is positioned on the outer side.

Classes IPC  ?

• A01G 1/00 - Horticulture; Culture des légumes (étiquettes ou plaques d'identification G09F 3/00, G09F 7/00)
• A01G 9/02 - Récipients, p. ex. pots ou jardinières Verres pour la culture des fleurs

Abrégé

A microorganism detection method that: is highly versatile, being applicable to both a test for specified microorganisms and a microbial enumeration test using the same test conditions for Kampo extract preparations and crude drugs containing a wide variety of antimicrobial substances; makes it possible to reduce the impact of antimicrobial substances in a test sample effectively; and allows the detection of target microorganisms with a high degree of precision. Said method, which is used to detect microorganisms in a test sample that exhibits antimicrobial activity, is characterized by having a step in which a liquid sample containing a test sample that exhibits antimicrobial activity is prepared and a step in which target microorganisms are cultured in a culture medium. Said method is also characterized in that a (meth)acrylic-acid-ester synthetic adsorbent is made to act on the liquid sample and/or the culture medium.

Classes IPC  ?

• C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique

Abrégé

The present invention addresses the problem of providing a method for artificially culturing Wolfiporia cocos whereby high-quality Wolfiporia cocos can be efficiently produced without contamination by sawdust during the culturing process. An artificial culturing method for overcoming this problem is characterized in comprising the steps of (1) inoculating an ammonium-salt-containing mushroom bed with the spawn of Poria cocos, using sawdust as a substrate, (2) cultivating the spawn of Poria cocos so as to form a hyphal mat on the surface of the mushroom bed, (3) inoculating the resulting hyphal mat with seed Wolfiporia cocos, and (4) enlarging the Wolfiporia cocos inoculum.

Classes IPC  ?

• A01G 1/04 - Culture des champignons (composts ou engrais pour la culture des champignons C05)
• C12N 1/14 - ChampignonsLeurs milieux de culture

Abrégé

Provided are a method for producing a sanshool, which can produce a sanshool in a short process and with high stereoselectivity, as well as a novel diene iron complex compound that is a stable intermediate useful for the production method. The diene iron complex compound is represented by the following general formula (I): 2 represents a hydrogen atom and the other one thereof represents a structure represented by the following formula (II)): (in which R represents a hydrogen atom, a hydroxyl group, or a methyl group).

Classes IPC  ?

• C07F 15/02 - Composés du fer
• C07C 233/09 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués avec des atomes de carbone de groupes carboxamide liés à des atomes de carbone d'un squelette carboné acyclique non saturé
• C07C 231/12 - Préparation d'amides d'acides carboxyliques par des réactions n'impliquant pas la formation de groupes carboxamide

Abrégé

The invention intends to provide a bioassay method using a simple in-vitro test for Daikinchuto, and further to provide a more highly accurate method for quality control of Daikenchuto using the same. These methods are a bioassay method for the pharmacological activity of Daikenchuto, characterized in that a test sample containing Daikenchuto is added to cultured serotonin-producing cells, and the serotonin content in the culture supernatant is subsequently measured; and a quality control method for Daikenchuto preparations in which the pharmacological activity of a test preparation and a reference preparation for which the pharmacological effect as Daikenchuto has been clinically confirmed are evaluated under the same conditions, and the equivalence of the reference preparation and testing preparation is evaluated.

Classes IPC  ?

• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• G01N 33/94 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des narcotiques

Abrégé

Provided are a method for producing a sanshool, which method has a short process and exhibits high stereoselectivity, as well as an iron carbonyl complex compound that is an intermediate useful for the production method. A diene iron complex compound characterized by being represented by the following general formula (I): 2 represents a hydrogen atom and the other one thereof represents a structure represented by the following formula (II)): (in which R represents a hydrogen atom, a hydroxyl group, or a methyl group).

Classes IPC  ?

• C07F 15/02 - Composés du fer
• C07C 231/12 - Préparation d'amides d'acides carboxyliques par des réactions n'impliquant pas la formation de groupes carboxamide
• C07C 233/12 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un radical hydrocarboné substitué par des atomes d'halogène ou par des groupes nitro ou nitroso

Abrégé

The present invention enables an increase in efficiency and accuracy in evaluating a multi-component substance. The present invention is characterized by being provided with: an FP creation unit (3) that, as a subject FP, creates an FP in a particular detection wavelength from a 3D chromatograph of the multi-component substance to be evaluated; a peak pattern creation unit (7) that creates a peak pattern configured from n+1 peaks including n peaks present in at least one of before and after in the direction of the time axis with respect to the respective peaks of the subject FP and a reference FP; a peak attribution unit (9) that compares the peak pattern and the UV spectrum of the peaks and specifies corresponding peaks; and an evaluation unit (11) that performs a comparative evaluation of the attributed peaks and the peaks of a plurality of reference FPs.

Classes IPC  ?

• G01N 30/86 - Analyse des signaux
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

The present invention can contribute to an improvement in efficiency and accuracy in evaluating a subject of evaluation. The present invention is provided with an FP creation unit (3) that creates a subject FP configured from the peak of the peaks detected at a specific wavelength from a 3D chromatograph of a multi-component drug that is the subject of evaluation, the retention time of said peak, and the UV spectrum of said peak, and a device that is for evaluating a multi-component drug and that contains the FP creation unit (3) is characterized by being provided with: a reference FP selection unit (5) that selects a reference FP suited for subject FP peak attribution from a plurality of reference FPs; a peak pattern creation unit (7) that creates a peak pattern configured from, for example, three peaks including two peaks present in at least one of before and after in the direction of the time axis with respect to the peaks respectively of the subject FP and the selected reference FP; a peak attribution unit (9) that compares the peak pattern and the UV spectrum of the peaks and specifies corresponding peaks; and an evaluation unit (11) that performs a comparative evaluation, for example by means of an MT method, of the attributed peaks and the peaks of the plurality of reference FPs.

Classes IPC  ?

• G01N 30/86 - Analyse des signaux
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

The present invention can contribute to increasing efficiency and precision in evaluating an evaluation subject. A peak attribution device (1), which is for attributing the peaks of an FP configured from peaks detected from the chromatograph of a multi-component substance and the retention time of the peaks, is characterized by being provided with: a peak pattern creation unit (7) that creates a peak pattern by means of n+1 peaks including n peaks present in at least one of the position before and after in the direction of the time axis with respect to each of the peaks of a subject FP, which is an FP as an evaluation subject, and a reference FP, which is an FP as an evaluation reference; and a peak attribution unit (9) that compares the peak patterns and specifies corresponding peaks.

Classes IPC  ?

• G01N 30/86 - Analyse des signaux
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

The present invention can contribute to increasing evaluation precision and efficiency. A similarity evaluation device (1) for aggregated data that evaluates the similarity between the aggregated data, which is the aggregate of a plurality of data, is characterized by being provided with: a patternizing unit (3) that patternizes each datum of the aggregated data by means of a selected criterion; a match count extraction unit (5) that compares each patternized datum in a round-robin fashion and determines the match count; and a match degree determination unit (7) that determines the degree of match using the Tanimoto coefficient on the basis of the determined match count. The similarity evaluation device (1) is further characterized by easily and rapidly evaluating the similarity of the aggregated data.

Classes IPC  ?

• G01N 30/86 - Analyse des signaux
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

The present invention is able to increase the efficiency and precision of evaluation of a multi-component substance. The present invention is characterized by being provided with: a step (173) for creating a subject FP; a step (149) for attributing subject FP peaks; a step (151) for creating subject FP peak feature quantities; a step (153) for creating subject FP type two; a step (155) for creating subject FP region splitting feature quantities; a step (157) for consolidating subject FP feature quantities; and an evaluation step (171). The present invention is further characterized by consolidating the subject FP peak feature quantities and the subject FP region splitting feature quantities, creating subject FP consolidated feature quantities, and by performing a comparative evaluation on reference FP consolidated feature quantities that are on the basis of a plurality of reference FPs of the multi-component substance that are the evaluation references corresponding to the subject FP consolidated feature quantities, and the subject FP consolidated feature quantities.

Classes IPC  ?

• G01N 30/86 - Analyse des signaux
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

In order to enable improved accuracy and efficiency of the evaluation of a multicomponent substance, the present invention is characterized by being provided with an object FP creation step (173), an object FP peak attribution step (149), an object FP peak characteristic amount creation step (151), an object FP type 2 creation step (153), an object FP region division characteristic amount creation step (155), an object FP characteristic amount integration step (157), and an evaluation step (171), and characterized in that an object FP peak characteristic amount and an object FP region division characteristic amount are integrated to create an object FP integration characteristic amount, and the object FP integration characteristic amount and a reference FP integration characteristic amount corresponding to the object FP integration characteristic amount and based on a plurality of reference FPs of multicomponent substances serving as evaluation references are compared and evaluated.

Classes IPC  ?

• G01N 30/86 - Analyse des signaux
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

The object of the invention is to find the actions of the crude drugs contained in Daikenchuto or their components and the synergistic effect of the components with one another or with other pharmacologically active substances, and to provide new drugs or pharmaceutical compositions based on the findings. The invention is directed to intestinal peristaltic motility-enhancers comprising an effective amount of hydroxy-α-sanshool or a plant containing the same or an extract thereof; compositions comprising a combination of hydroxy-α-sanshool or a plant containing the same or an extract thereof and capsaicin or a plant containing the same or an extract thereof or bethanechol or a salt thereof; as well as a method for improving intestinal motility which comprises administering the composition to a patient.

Classes IPC  ?

• A01N 37/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques
• A61K 31/21 - Esters, p. ex. nitroglycérine, sélénocyanates
• A01N 37/18 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant le groupe —CO—N, p. ex. amides ou imides d'acide carboxyliqueLeurs thio-analogues
• A61K 31/16 - Amides, p. ex. acides hydroxamiques
• A61K 31/4965 - Pyrazines non condensées

Abrégé

The purpose of the present invention is to provide a bioassay method using a simple in vitro test for daikenchuto, and further to provide a more highly accurate quality management method for daikenchuto using the same. These methods are a bioassay method for the pharmacological activity of daikenchuto, characterized in that a test sample containing daikenchuto is added to cultured serotonin-producing cells, and the serotonin content in the culture supernatant is subsequently measured; and a quality management method for daikenchuto preparations in which the pharmacological activity of a test preparation and a reference preparation for which the pharmacological effect in terms of daikenchuto has been clinically confirmed are evaluated under the same conditions, and the equivalence of the reference preparation and testing preparation is evaluated.

Classes IPC  ?

• C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

Provided are a method for producing a sanshool, the method having a short process and being highly stereoselective, and an iron carbonyl complex compound which is a useful intermediate for the method of production. A diene iron complex compound is characterized by being represented by General Formula (I) (in the formula, A represents CO, P(RA)3, CN, NO, SO(RA)2, or N(RA)2, where RA represents a C1-4 linear or branched alkyl group, or a C6-12 aryl group; either one of R1 and R2 represents a hydrogen atom, and the other has the structure represented by General Formula (II)) (in the formula, R represents a hydrogen atom, a hydroxyl group, or a methyl group).

Classes IPC  ?

• C07C 233/09 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués avec des atomes de carbone de groupes carboxamide liés à des atomes de carbone d'un squelette carboné acyclique non saturé
• C07C 231/12 - Préparation d'amides d'acides carboxyliques par des réactions n'impliquant pas la formation de groupes carboxamide
• C07C 233/20 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un radical hydrocarboné substitué par des atomes d'oxygène liés par des liaisons simples avec le radical hydrocarboné substitué lié à l'atome d'azote du groupe carboxamide par un atome de carbone acyclique ayant l'atome de carbone du groupe carboxamide lié à un atome de carbone d'un squelette carboné acyclique non saturé
• C07C 255/07 - Mononitriles
• C07F 15/02 - Composés du fer

Abrégé

The objectives are to find a substance or a composition capable of promoting the production of ghrelin with physiological activities such as growth hormone secretion effect, and to provide a pharmaceutical comprising it as the active ingredient. The pharmaceutical is a ghrelin production promoter comprising Rikkunshi-to as the active ingredient.

Classes IPC  ?

• A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
• A61K 36/284 - Atractylodes
• A61K 36/25 - Araliaceae (famille du ginseng), p. ex. lierre, aralia, schefflera ou tétrapanax
• A61K 36/8888 - Pinellia
• A61K 36/076 - Poria
• A61K 36/484 - Glycyrrhiza (réglisse)
• A61K 36/725 - Ziziphus, p. ex. jujube
• A61K 36/752 - Citrus, p. ex. citron vert, orange ou citron
• A61K 36/258 - Panax (ginseng)
• A61K 36/48 - Fabaceae ou Leguminosae (famille du pois ou des légumineuses)CaesalpiniaceaeMimosaceaePapilionaceae
• A61K 36/906 - Zingiberaceae (famille du gingembre)

Abrégé

Disclosed is an efficient cultivation method of Panax ginseng C.A.Mey. which prevents damage from continuous cropping particular to Panax ginseng C.A.Mey., and is capable of reducing the work involved in cultivation. Said method includes: a Panax ginseng C.A.Mey. cultivation method involving securing seedlings of Panax ginseng C.A.Mey. to a cultivation floor comprising particles mainly comprising at least one kind of particles selected from a group consisting of sand, gravel and pebbles, and allowing at least one part of the rhizosphere of the Panax ginseng C.A.Mey. seedlings to be in constant contact with non-circulating running water; and a Panax ginseng C.A.Mey. cultivation method involving securing seeds of Panax ginseng C.A.Mey. to a cultivation floor comprising particles mainly comprising at least one kind of particles selected from a group consisting of sand, gravel and pebbles, and allowing at least one part of the Panax ginseng C.A.Mey. seeds to be in constant contact with non-circulating running water.

Classes IPC  ?

• A01G 1/00 - Horticulture; Culture des légumes (étiquettes ou plaques d'identification G09F 3/00, G09F 7/00)
• A01G 7/00 - Botanique en général
• A01G 31/00 - Culture hors-sol, p. ex. hydroponie

Abrégé

An in-vitro bioassay method for yokukansan, involving competitively binding a labeled ligand and yokukansan with cells or cell membranes expressing glutamate receptors, measuring the binding activity of yokukansan, and determining the pharmacological activity of yokukansan from the measurement.

Classes IPC  ?

• G01N 33/567 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet utilisant un support spécifique ou des protéines réceptrices comme réactifs pour la formation de liaisons par ligand utilisant un extrait de tissu ou d'organe comme agent de liaison

Abrégé

The invention intends to find out a bioassay system with an in-vitro test capable of ensuring the higher quality of yokukansan, and provides a bioassay method for yokukansan, comprising adding glutamate in an amount sufficient to induce cell death and yokukansan to a medium for culturing cells, and evaluating pharmacological activity value of yokukansan from viability of the cultured cells in the medium.

Classes IPC  ?

• C12P 1/00 - Préparation de composés ou de compositions, non prévue dans les groupes , utilisant des micro-organismes ou des enzymesProcédés généraux de préparation de composés ou de compositions utilisant des micro-organismes ou des enzymes

Abrégé

The objectives are to find a substance or a composition capable of promoting the production of ghrelin with physiological activities such as growth hormone secretion effect, and to provide a pharmaceutical comprising it as the active ingredient. The pharmaceutical is a ghrelin production promoter comprising Rikkunshi-to as the active ingredient.

Classes IPC  ?

• A61K 61/00 -
• A61K 36/284 - Atractylodes
• A61K 36/25 - Araliaceae (famille du ginseng), p. ex. lierre, aralia, schefflera ou tétrapanax
• A61K 36/8888 - Pinellia
• A61K 36/076 - Poria
• A61K 36/484 - Glycyrrhiza (réglisse)
• A61K 36/725 - Ziziphus, p. ex. jujube
• A61K 36/752 - Citrus, p. ex. citron vert, orange ou citron
• A61K 36/258 - Panax (ginseng)
• A61K 36/48 - Fabaceae ou Leguminosae (famille du pois ou des légumineuses)CaesalpiniaceaeMimosaceaePapilionaceae
• A61K 36/906 - Zingiberaceae (famille du gingembre)

Abrégé

It is an object of the invention to discover a substance that effectively increases the production of adrenomedullin, as well as to provide an adrenomedullin production-enhancing agent utilizing this substance. The adrenomedullin production-enhancing agent is characterized by inclusion of a ginsenoside, a sanshool, and/or a shogaol as active ingredients.

Classes IPC  ?

• A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
• A61K 31/164 - Amides, p. ex. acides hydroxamiques d'un acide carboxylique avec un aminoalcool, p. ex. céramides
• C07J 9/00 - Stéroïdes normaux contenant du carbone, de l'hydrogène, un halogène ou de l'oxygène, substitués en position 17bèta par une chaîne de plus de deux atomes de carbone, p. ex. cholane, cholestane, coprostane
• A61K 36/75 - Rutaceae (famille de la rue)
• A61K 36/9068 - Zingiber, p. ex. gingembre
• C07J 17/00 - Stéroïdes normaux contenant du carbone, de l'hydrogène, un halogène, ou de l'oxygène, ayant un hétérocycle contenant de l'oxygène non condensé avec le squelette du cyclopenta[a]hydrophénanthrène

Abrégé

The invention intends to find out an in-vitro bioassay system capable of ensuring qualities of yokukansan to a higher degree, and provides a bioassay method for yokukansan, comprising competitively reacting labeled ligand and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring binding activity of yokukansan from the amount of the labeled ligand bound, and a bioassay method for yokukansan, comprising reacting labeled GTP and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring receptor-agonist activity of yokukansan from the amount of the labeled GTP bound.

Classes IPC  ?

• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet

Abrégé

A method for analyzing a dithiocarbamate pesticide is provided. The method includes the steps of: adding a crude drug, a preparation containing the same, or a treated product thereof, an aqueous acid catalyst solution, L-cysteine or a salt thereof, and an organic solvent for extraction to a reaction vessel, sealing the vessel, carrying out microwave irradiation, digesting a dithiocarbamate pesticide existing in the crude drug or the preparation containing the same into carbon disulfide, carrying out fractional extraction using the above organic solvent, and then analyzing the extract.

Classes IPC  ?

• G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
• G01N 1/18 - Dispositifs pour prélever des échantillons à l'état liquide ou fluide avec mesures prises pour diviser des échantillons en plusieurs parties

Abrégé

To find out an in-vitro bioassay system capable of ensuring qualities of yokukansan to a higher degree, it is intended to provide a method of bioassaying yokukansan characterized by comprising adding a yokukansan-containing test sample to astroglial cells to be cultivated under the condition of thiamine deficiency, and then determining the pharmacological activity value of yokukansan based on the glutamic acid or neutral red intake level in the cultivated astroglial cells.

Classes IPC  ?

• C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
• C12P 21/06 - Préparation de peptides ou de protéines préparés par hydrolyse d'une liaison peptidique, p. ex. hydrolysats
• C07K 1/00 - Procédés généraux de préparation de peptides

Abrégé

There is provided a microbial culture medium and a microbial culture method for adequately growing a target bacterium contained in an antibacterial test sample. The microbial culture medium for growing a target bacterium contained in an antibacterial test sample is composed of a basal medium for microbial culture, and acid clay or activated clay contained in the basal medium. The microbial culture method for growing a target bacterium contained in an antibacterial test sample using a microbial culture medium includes adding acid clay or activated clay to a solution of the test sample. It is preferred that the acid clay or activated clay be combined with activated carbon.

Classes IPC  ?

• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
• C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
• C12N 1/20 - BactériesLeurs milieux de culture

Abrégé

To find out an in vitro bioassay system capable of ensuring improved qualities of yokkansan, it is intended to provide a method of bioassaying yokkansan characterized by comprising treating cells or cell membranes expressing a glutamate receptor competitively with a labeled ligand and yokkansan, measuring the binding activity of the yokkansan, and then evaluating the pharmacological activity of the yokkansan based on the thus obtained data.

Classes IPC  ?

• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• A61K 36/18 - Magnoliophyta (angiospermes)
• A61K 36/48 - Fabaceae ou Leguminosae (famille du pois ou des légumineuses)CaesalpiniaceaeMimosaceaePapilionaceae
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• G01N 33/15 - Préparations médicinales

Abrégé

It is intended to find an in vitro bioassay system capable of ensuring improved qualities yokukansan (a Chinese medicine). Thus, a method of bioassaying yokukansan, which is characterized by comprising adding glutamic acid in an amount sufficient for inducing cell death and yokukansan to a medium in which cells are to be cultured and evaluating the pharmacological activity of yokukansan based on the survival rate of the cells having been cultured in the medium, is provided.

Classes IPC  ?

• G01N 33/15 - Préparations médicinales
• A61K 36/18 - Magnoliophyta (angiospermes)
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• C12N 5/06 -
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

It is intended to find a substance having an action of effectively enhancing the production of adrenomedullin and to provide an adrenomedullin production enhancer using this substance. The adrenomedullin production enhancer is characterized by containing a ginsenoside, a sanshool and/or a shogaol as active ingredients.

Classes IPC  ?

• A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
• A61K 31/12 - Cétones
• A61K 31/16 - Amides, p. ex. acides hydroxamiques
• A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
• A61P 13/00 - Médicaments pour le traitement des troubles du système urinaire
• A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs
• A61P 19/00 - Médicaments pour le traitement des troubles du squelette
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes

Abrégé

It is intended to find a substance having an action of effectively enhancing the production of adrenomedullin and to provide an adrenomedullin production enhancer using this substance. The adrenomedullin production enhancer is characterized by containing a ginsenoside, a sanshool and/or a shogaol as active ingredients.

Classes IPC  ?

• A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
• A61K 31/12 - Cétones
• A61K 31/16 - Amides, p. ex. acides hydroxamiques
• A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
• A61P 13/00 - Médicaments pour le traitement des troubles du système urinaire
• A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs
• A61P 19/00 - Médicaments pour le traitement des troubles du squelette
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes

Abrégé

It is intended to find out an bioassay system using an in vitro test whereby the quality guarantee of yokkansan can be improved. Namely, a bioassay method for yokkansan characterized by comprising treating a cell or cell membrane expressing serotonin 1A receptor competitively with a labeled ligand and a test sample containing yokkansan and measuring the binding activity of yokkansan based on the amount of the labeled ligand having been bound, and a bioassay method for yokkansan characterized by comprising treating a cell or cell membrane expressing serotonin 1A receptor with a labeled GTP and a test sample containing yokkansan and measuring the agonistic activity to the receptor of yokkansan based on the amount of the labeled GTP having been bound are provided.

Classes IPC  ?

• A61K 36/18 - Magnoliophyta (angiospermes)
• A61P 25/24 - Antidépresseurs
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• C12N 15/00 - Techniques de mutation ou génie génétiqueADN ou ARN concernant le génie génétique, vecteurs, p. ex. plasmides, ou leur isolement, leur préparation ou leur purificationUtilisation d'hôtes pour ceux-ci
• C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
• G01N 33/15 - Préparations médicinales

Abrégé

Provided is a tablet composition containing Kampo extract having more excellent disintegration and dissolution properties than ever before. The tablet composition containing Kampo extract contains a Kampo extract powder, croscarmellose sodium, and sodium hydrogen carbonate. The Kampo extract powder is preferably at least one extract powder selected from the group consisting of Kakkonto, Kakkontokasenkyushin'i, Shoseiryuto, Tokishakuyakusan, Kamishoyosan, Keishibukuryogan, Hochuekkito, Bofutushosan, Goshajinkigan, Maobushisaishinto, Keishikajutsubuto, Juzentaihoto, Sokeikakketsuto, Shakuyakukanzoto, Keishininjinto, Tokakujokito, Yokukansan, Goreisan, and Eppikajutsuto.

Classes IPC  ?

• A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
• A61K 9/20 - Pilules, pastilles ou comprimés
• A61K 47/02 - Composés inorganiques
• A61K 47/38 - CelluloseSes dérivés

Abrégé

Disclosed is a method for the analysis of a dithiocarbamate agrichemical, which can ensure the accuracy of the analysis and can also combine both ease of operation and rapidity. Specifically disclosed is a method for the analysis of a dithiocarbamate agrichemical, which comprises the steps of: charging a galenical, a preparation containing the galenical or a treatment product of the galenical or the preparation, an aqueous acidic catalyst solution, L-cysteine or a salt thereof, and an organic extraction solvent into a reaction vessel, and hermetically sealing the reaction vessel; irradiating the reaction vessel with a microwave to decompose the dithiocarbamate agrichemical present in the galenical or the preparation into carbon disulfide; partitioning and extracting carbon disulfide into the organic solvent; and subjecting carbon disulfide to the analysis.

Classes IPC  ?

• G01N 31/00 - Recherche ou analyse des matériaux non biologiques par l'emploi des procédés chimiques spécifiés dans les sous-groupesAppareils spécialement adaptés à de tels procédés
• G01N 30/06 - Préparation
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes
• G01N 30/54 - Température
• G01N 30/60 - Préparation de la colonne
• G01N 30/74 - Détecteurs optiques

Abrégé

It is intended to provide a method whereby the species of a plant belonging to the genus Uncaria can be identified at a high accuracy. Namely, a method of identifying the species of a plant belonging to the genus Uncaria contained in a test sample which comprises comparing the base sequence in the ITS region of the ribosomal DNA of the plant contained in the test sample with at least one base sequence in the ITS region selected from among the base sequences represented by SEQ ID NOS:1 to 11.

Classes IPC  ?

• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• C12N 15/09 - Technologie d'ADN recombinant

Abrégé

To find out an in vitro bioassay system capable of ensuring improved qualities of yokkansan, it is intended to provide a method of bioassaying yokkansan characterized by comprising adding a yokkansan-containing test sample to astroglial cells having been cultured in a thiamine-deficient state, and then evaluating the pharmacological activity of the yokkansan based on the uptake of glutamic acid or neutral red in the cultured astroglial cells.

Classes IPC  ?

• C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables

Abrégé

A method of insect pests control characterized by, after putting insecticidal processing object in a pressure-resistant chamber, carrying out (i) reduction of pressure to a level of -0.1013 to -0.05 MPa, (ii) hermetically introducing carbon dioxide to a pressure of 0.6 to 1.0 MPa and maintaining the pressurized state for 15 to 90 min and (iii) pressure restoration through release of carbon dioxide to normal pressure and repeating the above (i) pressure reduction, (ii) pressurization and (iii) pressure restoration at least once. Further, there is provided an insect pests control apparatus for killing of insect pests living in an object through pressure reduction/pressurization/pressure restoration and through temperature control during pressurization, characterized by including a pressure-resistant chamber for accommodating the object; pressure reduction means for bringing the interior of the pressure-resistant chamber to a negative pressure; gas supply means for filling the interior of the pressure-resistant chamber with carbon dioxide to thereby attain pressurization; means for pressure reduction from a set pressure to a negative pressure; and temperature control means for controlling the temperature within the pressure-resistant chamber.

Classes IPC  ?

• A23L 3/015 - Conservation des aliments ou produits alimentaires, en général, p.ex. pasteurisation ou stérilisation, spécialement adaptée aux aliments ou produits alimentaires par un traitement utilisant une variation de pression, une secousse, une accélération ou un cisaillement
• A01M 1/00 - Systèmes fixes pour capturer ou détruire les insectes
• A01N 25/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles
• A01N 59/04 - Sulfure de carboneOxyde de carboneGaz carbonique
• A01P 7/04 - Insecticides

Produits et services

Laundry bleach; laundry starch; shoe and boot cream; polishing preparations; soap; detergents other than for use in manufacturing operations and for medical purposes; shampoos for pets; scouring preparations (cleansers); toilet soap; shampoos; toilet bowl detergents; medicated soap; dentifrices; cosmetics; make-up powder; toilet water; lotions for cosmetic purposes; skin lotions; cosmetic cream; sunscreen cream; hair care preparations; hair spray; hair tonics; hair rinses; perfumes; bath oils; bath salts not for medical purposes; perfumery; natural perfumery prepared from plant extracts; natural perfumery prepared from animal extracts; incense; fumigation preparations (perfumes); emery paper; emery cloth; abrasive paper.

Abrégé

A method for evaluation of a multi-component medicine by judging the degree of difference of the multi-component medicine to be evaluated from a group of multi-component medicines selected as a reference group by using a Mahalanobis distance obtained by combining the 3D-HPLC fingerprint data of a multi-component medicine with fingerprint data of 3D-HPLC of other multi-component medicines of the same kind forming a reference group, allocating variable axes in the MT method to the number of multi-component medicine and the elution time or detection wavelength of the fingerprint data, obtaining a unit space from the signal strength, and obtaining the Mahalanobis distance of the multi-component medicine from the unit space.

Classes IPC  ?

• G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
• G01N 31/00 - Recherche ou analyse des matériaux non biologiques par l'emploi des procédés chimiques spécifiés dans les sous-groupesAppareils spécialement adaptés à de tels procédés
• G06G 7/48 - Calculateurs analogiques pour des procédés, des systèmes ou des dispositifs spécifiques, p. ex. simulateurs

Abrégé

Disclosed is a microbial cell culture medium which can certainly proliferate a target bacterial cell contained in a sample having an antibacterial activity. Also disclosed is a method for culture of a microbial cell. Specifically disclosed is a microbial cell culture medium for proliferating a target bacterial cell contained in a sample having an antibacterial activity, which comprises a base culture medium for microbial cell culture and either one of acid clay and activated clay. Also specifically disclosed is a microbial cell culture method for proliferating a target bacterial cell contained in a sample having an antibacterial activity, in a microbial cell culture medium, wherein acid clay or activated clay is added to a solution of the sample. Preferably, activated carbon is used in combination with acid clay or activated clay.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique

Abrégé

It is intended to provide a tablet composition containing a Chinese herb extract which is superior in disintegration properties and elution properties to the existing ones. Namely, a tablet composition containing a Chinese herb extract which contains a Chinese herb extract powder, croscarmellose sodium and sodium hydrogencarbonate. As the Chinese herb extract powder, use can be appropriately made of at least one extract powder selected from the group consisting of kakkonto, kakkonto-kasenkyushinni, syoseiryuto, toki-syakuyaku-san, kami-syoyosan, keishi-bukuryogan, hotyu-ekkito, bofutusho-san, gosyajinkigan, maobushi-saishinto, keishi-ka-jutsubuto, juzentaihoto, sokei-kakketsuto, syakuyakukanzoto, keishi-ninjinto, tokaku-zyokito, yokkansan, gorei-to and eppika-zyututo.

Classes IPC  ?

• A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
• A61K 9/20 - Pilules, pastilles ou comprimés
• A61K 47/04 - Non-métauxLeurs composés
• A61K 47/38 - CelluloseSes dérivés

Abrégé

Ghrelin has physiological activities including a growth hormone-secreting activity. A substance or composition which can promote the production of ghrelin is now found. Thus, disclosed is a pharmaceutical comprising the substance or composition as an active ingredient. The pharmaceutical comprises 'Rikkunshi-to' (a kind of herbal medicine) as an active ingredient and can be used as a ghrelin production promoter.

Classes IPC  ?

• A61K 36/28 - Asteraceae ou Compositae (famille de l'aster ou du tournesol), p. ex. camomille, chrysanthème matricaire, achillée ou echinacée
• A61K 36/07 - Basidiomycota, p. ex. Cryptococcus
• A61K 36/18 - Magnoliophyta (angiospermes)
• A61K 36/23 - Apiaceae ou Umbelliferae (famille de la carotte), p. ex. aneth, cerfeuil, coriandre ou cumin
• A61K 36/48 - Fabaceae ou Leguminosae (famille du pois ou des légumineuses)CaesalpiniaceaeMimosaceaePapilionaceae
• A61K 36/75 - Rutaceae (famille de la rue)
• A61P 5/10 - Médicaments pour le traitement des troubles du système endocrinien des hormones de l'hypophyse postérieure, p. ex. ocytocine, ADH
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

A collagen synthesis promoter capable of exhibiting a satisfactory collagen synthesis promoting activity and a high skin conditioning potency. There is provided a collagen synthesis promoter comprising as an active ingredient an extract from the fruit of myrobalan, and provided a collagen synthesis promoter comprising as an active ingredient one or two or more members selected from the group consisting of chebulagic acid, chebulinic acid, gallic acid and corilagin. The provided collagen synthesis promoter is suitable for use as a skin external preparation or skin quality improver; and can impart moistness and suppleness to the skin, can effect texture conditioning and can sustain the water retaining power of superficial skin.

Classes IPC  ?

• A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés
• A61K 8/368 - Acides carboxyliquesLeurs sels ou anhydrides dans lesquels le groupe carboxyle est directement lié aux atomes de carbone du cycle aromatique
• A61K 8/37 - Esters d'acides carboxyliques
• A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
• A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
• A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
• A61K 36/18 - Magnoliophyta (angiospermes)
• A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations
• A61Q 19/00 - Préparations pour les soins de la peau

Produits et services

Marketing research and commercial information agencies

Produits et services

[ Pharmaceutical preparations, namely, pharmaceuticals used to treat disorders of the central nervous system, pharmaceuticals used to treat disorders of the peripheral nervous system, pharmaceuticals used to treat disorders of the sensory organs, anti allergic medicines, cardiovascular pharmaceuticals, pharmaceuticals used to treat disorders of the respiratory organs, pharmaceuticals used to treat disorders of the digestive organs, hormones for medical purposes, pharmaceuticals used to treat disorders of the urinary, genital and anal organs, pharmaceuticals used to treat disorders of the epidermis, vitamin preparations, amino acid preparations for medical use; nutritional additives for pharmaceuticals, pharmaceuticals used to treat metabolism problems, cellular function activating agents, tumor suppressing agents, agents for treating physically caused lesions, agents for treating chemically caused lesions, antibiotic preparations, chemotherapeutics, biological preparations for medical purposes, agents for destroying parasites, diagnostic preparations for medical purposes, radio-isotope markers for therapeutic or diagnostic use, narcotic pharmaceuticals, ] crude drugs, namely, medicinal herbal extracts, herbal teas and herbal mixtures for diagnosing, treating, curing, or preventing any disease [, mosquito-repellent incenses; fungicides; rat poison; insecticides, fumigation preparations for medical purposes; weed killers; insect repellents; antiseptics; lactose for medical purposes; lacteal flour for babies in the nature of infant formula; medicated lotions used to treat disorders of the epidermis; medicated cream used to treat disorders of the epidermis ]

Produits et services

[ laundry bleach; laundry starch; shoe and boot cream; polishing preparations; toilet soap; shampoos; toilet bowl detergents; medicated soap; dentifrices; cosmetics; make-up powder; toilet water; lotions for cosmetic purposes; skin lotions; cosmetic cream; sunscreen cream; hair care preparations; hair spray; hair tonics; hair rinses; perfumes; bath oils; bath salts not for medical purposes; perfumery; natural perfumery prepared from plant extracts; natural perfumery prepared from animal extracts ] [ Pharmaceutical preparations, namely, pharmaceuticals used to treat disorders of the central nervous system, pharmaceuticals used to treat disorders of the peripheral nervous system, pharmaceuticals used to treat disorders of the sensory organs, anti allergic medicines, cardiovascular pharmaceuticals, pharmaceuticals used to treat disorders of the respiratory organs, pharmaceuticals used to treat disorders of the digestive organs, hormones for medical purposes, pharmaceuticals used to treat disorders of the urinary, genital and anal organs, pharmaceuticals used to treat disorders of the epidermis, vitamin preparations, amino acid preparations for medical use; nutritional additives for pharmaceuticals, pharmaceuticals used to treat metabolism problems, cellular function activating agents, tumor suppressing agents, agents for treating physically caused lesions, agents for treating chemically caused lesions, antibiotic preparations, chemotherapeutics, biological preparations for medical purposes, agents for destroying parasites, diagnostic preparations for medical purposes, radio-isotope markers for therapeutic or diagnostic use, narcotic pharmaceuticals, ] crude drugs, namely, medicinal herbal extracts, herbal teas and herbal mixtures for diagnosing, treating, curing, or preventing any disease, [ mosquito-repellent incenses; fungicides; rat poison; insecticides, fumigation preparations for medical purposes; weed killers; insect repellents; antiseptics; lactose for medical purposes; lacteal flour for babies in the nature of infant formula; medicated lotions used to treat disorders of the epidermis; medicated cream used to treat disorders of the epidermis ]

Produits et services

Meats, fish, poultry and game; meat extracts; preserved, dried and cooked fruits and vegetables; jellies, jams, fruit sauces; eggs, milk and milk products; edible oils and fats; weed extracts for food, milk beverages (milk predominating). Herb extracts for food.