Abrégé

The present invention relates to a new method to promote malolactic fermentation (MLF) and/or growth of lactic acid bacteria in food products, in particular in red wines, using dried white wine lees.

Classes IPC  ?

• C12F 3/06 - Récupération des sous-produits à partir de la bière ou du vin
• C12G 1/08 - Enlèvement de la levure [dégorgeage]
• C12N 1/20 - Bactéries; Leurs milieux de culture
• C12P 7/56 - Acide lactique

Abrégé

Device (30) for monitoring toxic substances in water and a system comprising the same. The device (30) includes a first monitoring chamber (1) comprising at least one biofilm (5) and a fluorometer (6), wherein the fluorometer is configured to measure the fluorescence of the biofilm (5); a second reference chamber (2) comprising at least one biofilm (5) and a fluorometer (6), wherein the fluorometer is configured to measure the fluorescence of the biofilm (5); a purifying filter (8) located between the first chamber (1) and the second chamber (2) such that the same water flow runs through the first chamber (1) and the second chamber (2) after passing through the purifying filter (8). Both chambers (1,2) are configured to allow, in use, the housing module (10) to receive outside light. The device (30) further comprises a data acquisition unit (18) configured to acquire the fluorescence measurement from the fluorometer (6) of each chamber (1,2).

Classes IPC  ?

• G01N 33/18 - Eau
• G01N 21/64 - Fluorescence; Phosphorescence

Produits et services

Devices and electrodes for medical purposes; Medical devices for clinical neurophysiology; Test electrodes for medical use; Testing apparatus for medical purposes; Diagnostic apparatus for medical purposes. Design and development of medical technology; Medical research, biological and clinical research; Testing, authentication and quality control; Science and technology services; Design services; Clinical research; Technical research consultancy relating to medical devices; Design and development of new products; Scientific and technological design; Design and development of consumer products.

Abrégé

A method and system for guiding electrode placement on the scalp. The invention includes a touch sensor arranged along a section of a flexible LED strip configured for measuring a distance between surface landmarks of the skull; and a control module with different configured settings of electrode placement schemes. By locating different cranial landmarks marked with the touch sensor and confirmed with LED lighting, it allows to guide the precise location of each electrode by illuminating the corresponding points of the LED strip.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• G01B 7/14 - Dispositions pour la mesure caractérisées par l'utilisation de techniques électriques ou magnétiques pour mesurer la distance ou la marge entre des objets ou des ouvertures espacés

Abrégé

vcc ; vLL icc ; iLL z11 z22 2 ) and the switching control variable (σ); and generate and apply a control signal (15) on the switching device (22) to adjust the input voltage (vs) of the resonant tank (24) according to the switching control variable (σ).

Classes IPC  ?

• H02M 1/00 - APPAREILS POUR LA TRANSFORMATION DE COURANT ALTERNATIF EN COURANT ALTERNATIF, DE COURANT ALTERNATIF EN COURANT CONTINU OU VICE VERSA OU DE COURANT CONTINU EN COURANT CONTINU ET EMPLOYÉS AVEC LES RÉSEAUX DE DISTRIBUTION D'ÉNERGIE OU DES SYSTÈMES D'ALI; TRANSFORMATION D'UNE PUISSANCE D'ENTRÉE EN COURANT CONTINU OU COURANT ALTERNATIF EN UNE PUISSANCE DE SORTIE DE CHOC; LEUR COMMANDE OU RÉGULATION - Détails d'appareils pour transformation
• H02M 3/00 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu

Abrégé

The invention relates to a rheometer (1) and to a training method carried out by computational elements (7), which comprises: recording droplets generated, by means of a video camera (3); determining the frequency and size of the droplet generated, by means of a step of image processing carried out by the computational elements (7); determining a droplet formation regime; determining viscosity or, optionally, also other parameters of the rheological model of the droplets by means of the computational elements (7), which use surface tension, flow, droplet size and droplet generation frequency to determine viscosity; and generating a database that can be used by a processing unit to infer viscosity, by means of empirical methods or neural network training, using the droplet size and the frequency measured by means of a camera in communication with computational elements that carry out image processing steps.

Classes IPC  ?

• B01F 33/30 - Micromixeurs
• B01J 13/00 - Chimie des colloïdes, p.ex. production de substances colloïdales ou de leurs solutions, non prévue ailleurs; Fabrication de microcapsules ou de microbilles
• G01N 11/02 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en mesurant l'écoulement du matériau

Abrégé

Embodiments of the present disclosure provide near azeotropic, binary blends of refrigerants that have low GWP; method of retrofitting an existing heat transfer system with the said refrigerants; heat transfer systems comprising the said refrigerants, and the like. Embodiments of the present disclosure describe a refrigerant that is near azeotropic and comprises a binary blend of more than one of R1243zf, R1234ze(E), R1234yf, R152a, R1123, R32 refrigerants.

Classes IPC  ?

• C09K 5/04 - Substances qui subissent un changement d'état physique lors de leur utilisation le changement d'état se faisant par passage de l'état liquide à l'état vapeur ou vice versa

Produits et services

Publicaciones electrónicas descargables; folletos en soporte electrónico descargable; software descargable desde redes informáticas mundiales de información; aplicaciones de móviles; aplicaciones de software descargables. Campañas de marketing; campañas de mercado; Gestión de negocios comerciales; Administración comercial; Organización y dirección de exposiciones y ferias comerciales; Información sobre negocios; Consultoría profesional en negocios; Evaluación de oportunidades de negocio; Consultoría sobre organización y dirección de negocios; Servicios de promoción; Organización, activación y supervisión de planes de incentivos; Administración de programas de fidelización y de incentivos; Promoción de eventos especiales; Consultoría sobre informes de mercado; Organización de contactos comerciales y empresariales; ayuda a empresas industriales o comerciales en la dirección de sus negocios; servicios publicitarios para promover la sensibilización del público en materia de bienestar social; análisis y elaboración de informes estadísticos; preparación de informes de gestión, de negocios y económicos; estudios de negocios y de mercado. Educación; Formación; servicios de entretenimiento; actividades deportivas y culturales; preparación, celebración y organización de congresos, simposios, seminarios y conferencias; publicación de calendarios de eventos; suministro de publicaciones electrónicas en línea; Publicación de libros, documentos, publicaciones periódicas, catálogos y folletos; publicación de documentos en el ámbito de la formación, la ciencia, la legislación pública y los asuntos sociales.

Produits et services

Electronic publications, downloadable; Downloadable electronic brochures; Computer software downloadable from global computer information networks; Mobile apps; Downloadable software applications. Market campaigns; Market campaigns; Business management; Business administration; Arranging and conducting of commercial exhibitions and shows; Business information; Professional business consultancy; Evaluation of business opportunities; Business management and organization consultancy; Promotion services; Organisation, operation and supervision of an incentive scheme; Administration of loyalty and incentive schemes; Promotion of special events; Market reporting services; Arranging of commercial and business contacts; Commercial or industrial management assistance; Advertising services to promote public awareness in the field of social welfare; Statistical analysis and reporting; Preparing business reports, Preparing business reports and Preparation of economic reports; business and market studies. Teaching; Training; Entertainment services; Sporting and cultural activities; Arranging, conducting and organisation of congresses, Arranging, conducting and organisation of symposiums, Arranging, conducting and organisation of seminars and Arranging, conducting and organisation of conferences; Publication of calendars of events; Providing online electronic publications, not downloadable; Publication of books, Publishing of documents, publication of periodical publications, Publication of catalogues and Publication of leaflets; Publication of documents in the field of training, science, public law and social affairs.

Abrégé

The present invention relates to a hybrid nanomaterial comprising an octahedral crystalline cluster of formula [M06l'8(OH)a4(H2O)a2]-2H2O, wherein the crystalline cluster is supported on graphene. Furthermore, the invention relates to a method for preparing the hybrid nanomaterial of the invention, and to a gas detection system comprising at least: (a) a gas sensor provided with a hybrid nanomaterial according to the present invention; and (b) optical interrogation means and/or electrical interrogation means configured to interrogate the gas sensor.

Classes IPC  ?

• C01G 39/04 - Halogénures
• G01N 21/64 - Fluorescence; Phosphorescence
• G01N 27/00 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques

Produits et services

Chemical substances, Chemical materials and Chemical preparations for scientific use, Chemical products for use in agriculture, Chemical and organic compositions for use in the manufacture of food and beverages, Chemical preparations for use in the manufacture of pharmaceuticals, Chemicals for use in the pharmaceutical industry. Chemicals for pharmaceutical use. Industrial research, Technical research, Chemical research, Scientific research, Research relating to biotechnology, Genetic research, Research of foodstuffs, Bacteriological research, Medical research, Agricultural research, Biochemistry research services, Veterinary research, Pharmaceutical research, Laboratory services for agricultural research, Consultancy relating to research in the field of pharmacogenetics.

Abrégé

The present invention relates to a single-acting water-lithium bromide absorption heat pump that simultaneously produces heat and cold comprising a condenser (6) to condense part of the coolant connected to the first heating circuit (9), an evaporator (1) connected to the cooling circuit (13), an absorber (2) to absorb the steam originating from the evaporator (1) with the lithium bromide-rich solution originating from the generator (5), a first heat exchanger (3) between the heater (7) and the generator (5) to heat the solution low in lithium bromide originating from the absorber, a generator (5) to boil the solution connected to the heating circuit (14), a heater (7) between the absorber (2) and the first heat exchanger (3) to condense the remaining coolant and a second heat exchanger (4) between the first heat exchanger (3) and the absorber (2) connected to the second heating circuit (15).

Classes IPC  ?

• F25B 15/02 - Machines, installations ou systèmes à sorption, à marche continue, p.ex. à absorption sans gaz inerte

Abrégé

The present invention refers to a gas sensor comprising a hybrid material of perovskite and graphene, to the method for obtaining said sensor and to the gas detection method using said sensor.

Classes IPC  ?

• G01N 27/04 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance
• C01B 32/182 - Graphène

Abrégé

An electrode device for aEEG is disclosed. The electrode device includes a housing mounted on an adhesive element to adhere the electrode device to a skin surface of a patient; an electrode plate placed in the housing; and a wire connection for the electrode plate. The housing has a first protruding part that includes a conical-shaped hole for injecting and removing an electroconductive gel and that is disposed in the housing inclined outwardly at an angle between 50 degree and 80 degree with respect to the longitudinal direction of the skin surface. The housing also has a second protruding part that includes a hole for the introduction of the wire connection in order to be attached to the electrode plate. The second protruding part is disposed on the axis of the housing

Classes IPC  ?

• A61B 5/257 - Moyens adhésifs, p.ex. garnitures ou bandes adhésives
• A61B 5/263 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet caractérisées par les matériaux des électrodes

Abrégé

Method and system for the identification of compounds in complex biological or environmental samples by receiving (102) a mass spectrum (1) from a mass spectrometry coupled with a separation technique; for each data point (2) of the mass spectrum (1), annotating (106) in an annotation database (12) combinations of formulas and adducts the theoretical mass-to-charge ratio of which (m/z)T corresponds to the mass-to-charge ratio (m/z) measured of the data point (2); for each formula and adduct annotated, detecting (108) regions of interest in a retention time range (RT0-RT1) according to characterisation criteria; generating (110) an inclusion list (14) with the retention time ranges (RT0-RT1) and the theoretical mass-to-charge ratios (m/z)T of the formulas and adducts associated with the regions of interest; and sending (112) the inclusion list to a mass spectrometer for the identification of compounds in the sample by tandem mass spectrometry.

Classes IPC  ?

• G01N 30/72 - Spectromètres de masse
• G16C 20/20 - Identification d’entités moléculaires, de leurs parties ou de compositions chimiques
• H01J 49/00 - Spectromètres pour particules ou tubes séparateurs de particules
• G01N 30/86 - Analyse des signaux

Abrégé

The present invention relates to a highly sensitive method for the screening of COVID-19 based on the use of selected symptoms and a simple olfactory test requiring the identification of a scent. It further relates to a data processing device and computer program related thereto.

Classes IPC  ?

• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux

Abrégé

The present invention relates to a use of a dipeptide comprising proline and alanine as salty taste enhancer in an edible article comprising salt, to an edible composition comprising the dipeptide proline-alanine, and to the edible article that comprises it. In addition, the invention also relates to a method for enhancing salty taste and reducing content of salt in food and beverages.

Classes IPC  ?

• A23L 27/21 - ALIMENTS, PRODUITS ALIMENTAIRES OU BOISSONS NON ALCOOLISÉES NON COUVERTS PAR LES SOUS-CLASSES OU ; LEUR PRÉPARATION OU TRAITEMENT, p.ex. CUISSON, MODIFICATION DES QUALITÉS NUTRITIVES, TRAITEMENT PHYSIQUE ; CONSERVATION DES ALIMENTS OU PRODUITS ALIMENTAIRES EN GÉNÉRAL Édulcorants artificiels; Sels de table; Substituts diététiques du sel; Leur préparation ou leur traitement Épices, agents aromatiques ou condiments synthétiques contenant des acides aminés
• A23L 27/40 - Sels de table; Substituts diététiques du sel
• A23L 27/00 - ALIMENTS, PRODUITS ALIMENTAIRES OU BOISSONS NON ALCOOLISÉES NON COUVERTS PAR LES SOUS-CLASSES OU ; LEUR PRÉPARATION OU TRAITEMENT, p.ex. CUISSON, MODIFICATION DES QUALITÉS NUTRITIVES, TRAITEMENT PHYSIQUE ; CONSERVATION DES ALIMENTS OU PRODUITS ALIMENTAIRES EN GÉNÉRAL Édulcorants artificiels; Sels de table; Substituts diététiques du sel; Leur préparation ou leur traitement

Abrégé

Printing device comprising an ink reservoir that supplies ink to an exit of a nozzle forming an ink drop and comprising also a power supply that creates an electrostatic field which generates an inkjet, said inkjet carrying a net electrostatic charge and being deposited on a substrate for printing a three-dimensional item by means of a continuous fiber, characterized in that the printing device also comprises one or a plurality of electrodes that deflect said inkjet from a default trajectory in a continually controlled manner through modifying the voltage applied to each jet-deflection electrode. The printing method comprises the step of deflecting said inkjet from a default trajectory by continually modifying the electrostatic field generated around the inkjet by one or a plurality of electrodes.

Classes IPC  ?

• B29C 64/112 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des gouttelettes individuelles, p.ex. de buses de jet
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additive; Leurs parties constitutives ou accessoires à cet effet
• B29C 64/209 - Têtes; Buses
• B29C 64/393 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive

Produits et services

Teaching; Training; Entertainment services; Developing educational manuals; Organisation of training workshops; Organisation of examinations [educational]; Arranging of contests; Organization of exhibitions for cultural or educational purposes; Arranging and conducting of educational classes, Arranging and conducting of colloquiums, Arranging and conducting of conferences, Arranging and conducting of congresses, Arranging and conducting of seminars, Arranging and conducting of symposiums; Publication ofbooks, magazines, almanacs and journals; Lending library services, Arranging and conducting of on-campus classes; Publishing and reporting; Providing online electronic publications, not downloadable, Publication of material which can be accessed from databases or from the internet; Writing services for blogs; All the aforesaid services exclusively relating to projects involving the use of hydrogen as an energy source. Scientific and technological services, as well as related research and design services; industrial analysis, industrial research and industrial design services; Quality control and authentication; Advisory services relating to energy efficiency; Engineering services in the field of energy technology; Design and development of energy management software; Energy auditing; All the aforesaid services exclusively relating to projects involving the use of hydrogen as an energy source.

Abrégé

The invention relates to a device and method for vehicle-to-vehicle and vehicle-to-infrastructure communication which, from an automobile radar based on FMCW, allow the exchange of information between a vehicle and different infrastructures or between vehicles. These radars are already installed in vehicles for advanced driver assistance systems. The device comprises a signal sensing element (2) for sensing the signal emitted by the radar (1), a modulator (3) which modulates the signal sensed in the sensing element (2), and a radiant element (4) which transmits the signal modified in the modulator (3) to the radar (1). The method comprises the steps of emitting a coded signal from the radar (1) to a modulated target (6), modifying the signal in the modulated target (6) and reflecting it to the radar (1), digitising, filtering and storing the signal reflected in the modulated target (6) and generating a list of targets (6) detected.

Classes IPC  ?

• G01S 7/00 - DÉTERMINATION DE LA DIRECTION PAR RADIO; RADIO-NAVIGATION; DÉTERMINATION DE LA DISTANCE OU DE LA VITESSE EN UTILISANT DES ONDES RADIO; LOCALISATION OU DÉTECTION DE LA PRÉSENCE EN UTILISANT LA RÉFLEXION OU LA RERADIATION D'ONDES RADIO; DISPOSITIONS ANALOGUES UTILISANT D'AUTRES ONDES - Détails des systèmes correspondant aux groupes , ,
• G01S 13/82 - Systèmes utilisant la reradiation d'ondes radio, p.ex. du type radar secondaire; Systèmes analogues dans lesquels des signaux de type continu sont transmis
• G01S 13/931 - Radar ou systèmes analogues, spécialement adaptés pour des applications spécifiques pour prévenir les collisions de véhicules terrestres

Abrégé

The present invention relates to a composition based on mixed or specific agonists of the TAS2R5 receptors, mixed or specific agonists of the TAS2R39 receptors or in combinations thereof. The compositions of the present invention have the ability to modulate food intake either to decrease it or to increase it depending on whether there is greater activation or stimulation of TAS2R5 receptors or TAS2R39 receptors respectively. Likewise, the present invention relates to a method for modulating food intake based on the administration of the composition of the invention.

Classes IPC  ?

• A61K 31/353 - 3,4-Dihydrobenzopyranes, p.ex. chromane, catéchine
• A23L 33/00 - Modification de la qualité nutritive des aliments; Produits diététiques; Leur préparation ou leur traitement
• A61K 31/4745 - Quinoléines; Isoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. phénanthrolines
• A61K 31/51 - Thiamines, p.ex. vitamine B1
• A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme

Abrégé

A method for producing s-triazine or s-heptazine-based or carbon nitride-based coating or s-triazine or s-heptazine-based polymeric or oligomeric material and composite materials containing this material are proposed. The method comprises: a) obtaining a polyazine precursor solution by either adding a compound adding a compound containing amino or imino groups to a solution comprising a hydrogen ion scavenger and a halide-containing heterocyclic compound in one or more solvents; or adding a hydrogen ion scavenger to a solution comprising a heterocyclic compound containing both halide and amino or imino groups in one or more solvents; and b) obtaining a dried film by filtering and/or evaporating the one or more solvents and the hydrogen ion scavenger in the polyazine precursor solution in vacuum or a gas atmosphere; wherein the halide-containing heterocyclic compound and/or the heterocyclic compound containing both halide and amino or imino groups is a derivative of at least one of the following compounds: 1,2,4,5-tetrazine, s-triazine, tri-s-triazine or 1H-tetrazole. A polyazine-based composite material or carbon nitride coating obtainable by said method is also proposed. A method for posterior engraving such coatings by laser or electron beam radiation is also disclosed.

Classes IPC  ?

• C01B 21/082 - Composés contenant de l'azote et des non-métaux

Abrégé

The present invention to a group of compounds of formula (I) useful for the transfer of polyfluoroalkylthiol groups of at least two carbons atoms into a great variety of organic compounds as well as to the process for their preparation. The invention is also directed to the method for the polyfluoroalkylthiolation of an organic compound with the reagents of the invention.

Classes IPC  ?

• C07D 275/06 - Composés hétérocycliques contenant des cycles thiazole-1, 2 ou thiazole-1, 2 hydrogéné  condensés avec des carbocycles ou avec des systèmes carbocycliques avec des hétéro-atomes liés directement à l'atome de soufre du cycle
• C07C 311/03 - Sulfonamides ayant des atomes de soufre de groupes sulfonamide liés à des atomes de carbone acycliques d'un squelette carboné acyclique saturé ayant les atomes d'azote des groupes sulfonamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques
• C07C 311/17 - Sulfonamides ayant des atomes de soufre de groupes sulfonamide liés à des atomes de carbone de cycles aromatiques à six chaînons ayant l'atome d'azote d'au moins un des groupes sulfonamide lié à des atomes d'hydrogène ou à un atome de carbone acyclique à un atome de carbone acyclique d'un radical hydrocarboné substitué par des atomes d'oxygène liés par des liaisons simples
• C07C 311/52 - Y étant un hétéro-atome
• C07B 45/06 - Formation ou introduction de groupes fonctionnels contenant du soufre de groupes mercapto ou sulfure

Abrégé

The present invention relates to a gas sensor comprising a hybrid material of perovskite and graphene, to the process for obtaining such a sensor, and to the method for detecting gases using such a sensor.

Classes IPC  ?

• G01N 27/04 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance
• C01B 32/182 - Graphène
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites

Abrégé

An electrode device for aEEG is disclosed. The electrode device comprises a housing mounted on an adhesive element to adhere the electrode device to a skin surface of a patient; an electrode plate placed in the housing; and a wire connection for the electrode plate. The housing has a first protruding part that includes a conical-shaped hole for injecting and removing an electroconductive gel and that is disposed in the housing inclined outwardly at an angle between 50 degree and 80 degree with respect to the longitudinal direction of the skin surface. The housing also has a second protruding part that includes a hole for the introduction of the wire connection in order to be attached to the electrode plate. The second protruding part is disposed on the axis of the housing.

Classes IPC  ?

• A61B 5/291 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électroencéphalographie [EEG]

Abrégé

Disclosed is a device (30) for monitoring toxic substances in water and a system comprising same. The device includes a reference chamber (1) with a purifying filter (8) and a monitoring chamber (2) with an inert filter (9). Each of the two chambers (1, 2) also includes an inlet and an outlet for the flow of water and accommodates a biofilm (5) and a fluorometer (6) for measuring fluorescence. A data acquisition unit (18) acquires measurements from the fluorometer (6) of each chamber (1, 2), which can be compared to identify changes in the aquatic medium. The two chambers can include passive sensors (3) for organic pollutants and passive sensors (4) for inorganic pollutants, which, once analysed in a laboratory, allow the results obtained from the biofilm to be supplemented. The system includes a remote computer (21) for transmitting alarms to terminals (22).

Classes IPC  ?

• G01N 21/64 - Fluorescence; Phosphorescence

Abrégé

The invention relates to a family of Pd(II)-based catalysts of general formula (I) reproduced below for use in the production of olefin/polar vinyl monomer copolymers and olefin homopolymers. The invention also refers to ligands that are intermediates in the synthesis of the catalysts, to the process for the synthesis of homo- and copolymers using these catalysts, and to the homo- and copolymers thus obtained.

Classes IPC  ?

• C08F 110/02 - Ethylène
• C08F 210/02 - Ethylène
• C08F 4/659 - Composant couvert par le groupe contenant une liaison métal de transition-carbone

Abrégé

Method and system for the identification of compounds in complex biological or environmental samples. The method comprises: receiving (102) a mass spectrum (1) from a mass spectrometry coupled with a separation technique; for each data point (2) of the mass spectrum (1), annotating (106) in an annotation database (12) combinations of formulas and adducts the theoretical mass-to-charge ratio of which (m/z)T corresponds to the mass-to-charge ratio (m/z) measured of the data point (2); for each formula and adduct annotated, detecting (108) regions of interest in a retention time range (RT0-RT1) according to characterisation criteria; generating (110) an inclusion list (14) with the retention time ranges (RT0-RT1) and the theoretical mass-to-charge ratios (m/z)T of the formulas and adducts associated with the regions of interest; and sending (112) the inclusion list to a mass spectrometer for the identification of compounds in the sample by means of tandem mass spectrometry.

Classes IPC  ?

• G01N 27/00 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques
• G16C 20/20 - Identification d’entités moléculaires, de leurs parties ou de compositions chimiques
• G16C 20/70 - Apprentissage automatique, exploration de données ou chimiométrie
• G01N 30/86 - Analyse des signaux

Abrégé

Method and system for the identification of compounds in complex biological or environmental samples. The method comprises: receiving (102) a mass spectrum (1) from a mass spectrometry coupled with a separation technique; for each data point (2) of the mass spectrum (1), annotating (106) in an annotation database (12) combinations of formulas and adducts the theoretical mass-to-charge ratio of which (m/z)T01011) and the theoretical mass-to-charge ratios (m/z)T of the formulas and adducts associated with the regions of interest; and sending (112) the inclusion list to a mass spectrometer for the identification of compounds in the sample by means of tandem mass spectrometry.

Classes IPC  ?

• G16C 20/20 - Identification d’entités moléculaires, de leurs parties ou de compositions chimiques
• H01J 49/00 - Spectromètres pour particules ou tubes séparateurs de particules
• G01N 30/86 - Analyse des signaux

Abrégé

The present invention relates to a new blocking agent for a blocked isocyanate composition consisting of an oxime of an ester of gamma-cetoacid. The present invention also relates to a method of manufacturing a blocked isocyanate composition and to a method of deblocking a blocked isocyanate composition. The present invention relates to the use of the blocked isocyanate composition obtained for manufacturing synthetic or artificial leather or in textile applications.

Classes IPC  ?

• C08G 18/80 - Polyisocyanates bloqués
• C08G 18/28 - Polymérisats d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs caractérisés par l'emploi de composés spécifiés contenant un hydrogène actif
• C08G 18/70 - Polymérisats d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs caractérisés par les isocyanates ou isothiocyanates utilisés
• C08G 18/76 - Polyisocyanates ou polyisothiocyanates cycliques aromatiques
• C09D 175/04 - Polyuréthanes
• C08G 18/32 - Composés polyhydroxylés; Polyamines; Hydroxyamines

Abrégé

The present invention relates to a composition with hypoleptinemic and antihypertensive effect and to its use as a food supplement, functional food or drug for treating obesity, overweight and/or hypertension.

Classes IPC  ?

• A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
• A61P 3/04 - Anorexigènes; Médicaments de l'obésité
• A61P 9/12 - Antihypertenseurs

Abrégé

The present invention relates to methods for selecting a restrictive or a malabsorptive bariatric surgical procedure for a patient in need thereof, wherein the method comprises determining the circulating succinate level in a biofluid sample from said patient. These methods can be used to identify those subgroups of patients who are more likely to benefit from a restrictive or a malabsorptive bariatric surgical procedure, thereby improving financial and health outcomes. The invention also relates to methods for predicting, before bariatric surgery, type 2 diabetes remission after restrictive bariatric surgery in a patient suffering from type 2 diabetes. Finally, the invention relates to uses of circulating succinate levels as an effective predictive factor for selecting a bariatric surgical procedure for a patient, as well as an informative biomarker for predicting, before bariatric surgery, type 2 diabetes remission after restrictive bariatric surgery in a patient suffering from type 2 diabetes.

Classes IPC  ?

• G01N 33/53 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet

Abrégé

The present invention relates to a use of a dipeptide comprising proline and alanine as salty taste enhancer in an edible article comprising salt, to an edible composition comprising the dipeptide proline-alanine, and to the edible article that comprises it. In addition, the invention also relates to a method for enhancing salty taste and reducing content of salt in food and beverages.

Classes IPC  ?

• A23L 27/40 - Sels de table; Substituts diététiques du sel
• A23L 27/00 - ALIMENTS, PRODUITS ALIMENTAIRES OU BOISSONS NON ALCOOLISÉES NON COUVERTS PAR LES SOUS-CLASSES OU ; LEUR PRÉPARATION OU TRAITEMENT, p.ex. CUISSON, MODIFICATION DES QUALITÉS NUTRITIVES, TRAITEMENT PHYSIQUE ; CONSERVATION DES ALIMENTS OU PRODUITS ALIMENTAIRES EN GÉNÉRAL Édulcorants artificiels; Sels de table; Substituts diététiques du sel; Leur préparation ou leur traitement
• A23L 27/21 - ALIMENTS, PRODUITS ALIMENTAIRES OU BOISSONS NON ALCOOLISÉES NON COUVERTS PAR LES SOUS-CLASSES OU ; LEUR PRÉPARATION OU TRAITEMENT, p.ex. CUISSON, MODIFICATION DES QUALITÉS NUTRITIVES, TRAITEMENT PHYSIQUE ; CONSERVATION DES ALIMENTS OU PRODUITS ALIMENTAIRES EN GÉNÉRAL Édulcorants artificiels; Sels de table; Substituts diététiques du sel; Leur préparation ou leur traitement Épices, agents aromatiques ou condiments synthétiques contenant des acides aminés

Abrégé

The method for determining the speed of printing of a fiber and the length of a printed fiber comprises: supplying ink to a nozzle (2); forming an ink drop (3) at the exit of said nozzle (2); generating an ink jet (4) carrying a net electrostatic charge; deflecting said ink jet (4) periodically by one or a plurality of jet-deflection electrodes (15, 16); collecting the ink jet (4) on a substrate (7) repetitively forming a printed motif (6) by means of a continuous fiber; determining the width of the printed motif (6); calculating the speed of printing of fiber from the frequency of the jet-deflection signal and the width of the printed motif; calculating the length of fiber printed in a time interval from the frequency of the jet-deflection signal and from the width of the printed motif.

Classes IPC  ?

• B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux
• B29C 64/112 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des gouttelettes individuelles, p.ex. de buses de jet
• B29C 64/386 - Acquisition ou traitement de données pour la fabrication additive
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additive; Leurs parties constitutives ou accessoires à cet effet
• B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• D01D 5/00 - Formation des filaments, fils ou similaires
• B41J 2/02 - Machines à écrire ou mécanismes d'impression sélective caractérisés par le procédé d'impression ou de marquage pour lequel ils sont conçus caractérisés par la mise en contact sélective d'un liquide ou de particules avec un matériau d'impression à jet d'encre caractérisés par le procédé de formation du jet en produisant un jet d'encre continu

Abrégé

Printing device comprising an ink reservoir (1) that supplies ink to an exit of a nozzle (2) forming an ink drop (3) and comprising also a power supply that creates an electrostatic field which generates an inkjet (4), said inkjet (4) carrying a net electrostatic charge and being deposited on a substrate (7) for printing a three-dimensional item (5) by means of a continuous fiber, characterized in that the printing device also comprises one or a plurality of electrodes (15, 16) that deflect said inkjet (4) from a default trajectory in a continually controlled manner through modifying the voltage applied to each jet-deflection electrode (15, 16). The printing method comprises the step of deflecting said inkjet (4) from a default trajectory by continually modifying the electrostatic field generated around the inkjet (4) by one or a plurality of electrodes (15, 16).

Classes IPC  ?

• B29C 64/112 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des gouttelettes individuelles, p.ex. de buses de jet
• B29C 64/209 - Têtes; Buses
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additive; Leurs parties constitutives ou accessoires à cet effet
• B41J 2/095 - Machines à écrire ou mécanismes d'impression sélective caractérisés par le procédé d'impression ou de marquage pour lequel ils sont conçus caractérisés par la mise en contact sélective d'un liquide ou de particules avec un matériau d'impression à jet d'encre caractérisés par la commande du jet pour une déviation selon plusieurs angles différents du type à commande par champ électrique

Abrégé

Printing device comprising an ink reservoir (1) that supplies ink to an exit of a nozzle (2) forming an ink drop (3) and comprising also a power supply that creates an electrostatic field which generates an inkjet (4), said inkjet (4) carrying a net electrostatic charge and being deposited on a substrate (7) for printing a three-dimensional item (5) by means of a continuous fiber, characterized in that the printing device also comprises one or a plurality of electrodes (15, 16) that deflect said inkjet (4) from a default trajectory in a continually controlled manner through modifying the voltage applied to each jet-deflection electrode (15, 16). The printing method comprises the step of deflecting said inkjet (4) from a default trajectory by continually modifying the electrostatic field generated around the inkjet (4) by one or a plurality of electrodes (15, 16).

Classes IPC  ?

• B29C 64/112 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des gouttelettes individuelles, p.ex. de buses de jet
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additive; Leurs parties constitutives ou accessoires à cet effet
• B29C 64/209 - Têtes; Buses
• B41J 2/095 - Machines à écrire ou mécanismes d'impression sélective caractérisés par le procédé d'impression ou de marquage pour lequel ils sont conçus caractérisés par la mise en contact sélective d'un liquide ou de particules avec un matériau d'impression à jet d'encre caractérisés par la commande du jet pour une déviation selon plusieurs angles différents du type à commande par champ électrique

Abrégé

The present invention relates to kits suitable for determining the ratio of succinate-producing bacteria to succinate-consuming bacteria in a stool sample from a subject, in particular the (Prevotellaceae+Veillonellaceae)/(Odoribacteriaceae+Clostridiaceae) ratio, or for determining the succinate level in a biofluid sample from a subject. The invention also relates to a method for determining whether a targeted intervention directed at reducing the levels of circulating succinate in a subject has been effective. Finally, the invention relates to targeted interventions for use in the prevention and/or treatment of a disease associated with increased levels of circulating succinate in a patient.

Classes IPC  ?

• C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
• A61K 35/741 - Probiotiques

Abrégé

1 are as described herein. Also disclosed are a pharmaceutical composition containing the compound and a method of using the compound for treating cancer, such as renal cancer.

Classes IPC  ?

• C07D 493/08 - Systèmes pontés
• A61P 35/00 - Agents anticancéreux
• C07D 495/08 - Systèmes pontés
• C07D 471/08 - Systèmes pontés

Abrégé

The invention provides an in vitro method, kits, uses of said kits and of reagents, for determining the prognosis of an HIV-infected subject having an undetectable viral load in the absence of antiretroviral treatment (or of an Ellite Controler HIV-infected subject) by determining the expression level of at least one biomarker selected from the group consisting of valine, iminodiacetic acid, 2-ketoisocaproic acid, pyruvic acid, alpha tocopherol, succinic acid, and glycolic acid in a sample from said subject, and comparing the expression level of said at least one biomarker with a reference value.

Classes IPC  ?

• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus

Abrégé

The present invention relates to a device and method for the preparation of platelet rich plasma, and to the plasma obtained by employing said device and method. The method comprises evaporating and dialysing plasma with the device of the invention to provide a plasma enriched in platelets and non-platelet biomolecules. The plasma thus obtained shows improved regenerative properties with respect to other plasma preparations.

Classes IPC  ?

• A61M 1/02 - Appareils pour transfusion sanguine d'un corps à un autre
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c. à d. hémofiltration, diafiltration
• B01D 19/00 - Dégazage de liquides
• B01D 3/14 - Distillation fractionnée

Abrégé

The present invention relates to a microfluidic device for the detection of circulating tumour cells (CTCs) in a fluid sample. The invention also relates to an in vitro method for the detection and/or quantification of circulating tumour cells (CTCs) in a fluid sample. Further, the invention relates to in vitro methods for (a) diagnosing a tumour and/or metastasis in a subject, and (b) determining the prognosis of a subject suffering from a tumour and/or metastasis. Finally, the invention refers to a kit comprising (a) a microfluidic device according to the first aspect of the invention, and (b) labelled probes targeting a first CTCs surface marker and, optionally, at least a second CTCs surface marker.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
• G01N 15/14 - Recherche par des moyens électro-optiques
• G01N 33/574 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour le cancer
• C12N 5/09 - Cellules tumorales

Abrégé

The present invention relates to kits suitable for determining the ratio of succinate- producing bacteria to succinate-consuming bacteria in a stool sample from a subject, in particular the (Prevotellaceae+ Veillonellaceae) / (Odoribacteriaceae+ Clostridiaceae)ratio, or for determining the succinate level in a biofluid sample from a subject. The invention also relates to a method for determining whether a targeted intervention directed at reducing the levels of circulating succinate in a subject has been effective. Finally, the invention relates to targeted interventions for use in the prevention and/or treatment of a disease associated with increased levels of circulating succinate in a patient.

Classes IPC  ?

• C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
• A61K 35/741 - Probiotiques
• A23L 33/135 - Bactéries ou leurs dérivés, p.ex. probiotiques
• A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
• A61P 3/04 - Anorexigènes; Médicaments de l'obésité
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• C12N 1/20 - Bactéries; Leurs milieux de culture
• C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions
• G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique

Abrégé

The present invention provides methods for identifying those mesenchymal stem cell populations that will be useful in cell therapy applicable in regenerative medicine, or selecting those MSC populations having a predominantly pro-inflammatory phenotype, and therefore applicable in those cell therapies where immune system activation is essential. The invention also provides enriched MSC populations in a more immunosuppressive subpopulation which secretes large amounts of transforming growth factor beta (TGFbß1) (similar to M2 macrophages or macrophages with anti-inflammatory phenotype).

Classes IPC  ?

• C12Q 1/6881 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour le typage de tissu ou de cellule, p.ex. sondes d’antigène leucocytaire humain [HLA]
• A61K 35/28 - Moelle osseuse; Cellules souches hématopoïétiques; Cellules souches mésenchymateuses de toutes origines, p.ex. cellules souches dérivées de tissu adipeux
• C12N 5/0775 - Cellules souches mésenchymateuses; Cellules souches dérivées du tissu adipeux

Abrégé

The invention relates to a porous material for the detection of Candida albicans, to a diagnostic method using same, and to a preparation method thereof. Specifically, the invention describes the production of a new porous material designed to recognise the DNA of the pathogenic microorganism Candida albicans, as well as the use thereof in a rapid, high-sensitivity in vitro diagnostic method.

Classes IPC  ?

• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques

Abrégé

Disclosed is a compound of formula (I) in which a, R1- R5 and X1 are as described herein. Also disclosed are a pharmaceutical composition containing the compound and a method of using the compound for treating cancer, such as renal cancer.

Classes IPC  ?

• C07D 493/08 - Systèmes pontés
• A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
• A61P 35/00 - Agents anticancéreux

Abrégé

Disclosed is a compound of formula (I) in which a, R1- R5and X1are as described herein. Also disclosed are a pharmaceutical composition containing the compound and a method of using the compound for treating cancer, such as renal cancer.

Classes IPC  ?

• C07D 493/08 - Systèmes pontés
• A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
• A61P 35/00 - Agents anticancéreux

Abrégé

A device for the total suppression of Vortex-induced vibrations (VIV) that structures suffer when exposed to currents. Typical marine structures that are prone to VIV are riser pipes, spar buoys and platforms, tendons, catenaries, mooring systems, etc. The invention not only completely suppresses VIV in the structures but also generate drag reductions in the structures. The device comprises a rigid mesh (1) formed by a rigid grid pattern of intersecting elements with certain mesh densities and sizes. The suppression system is to be installed around a structure (2) at a specific fixed distance, thereby resulting in a rigid cylindrical mesh of radius (r) with a size (s) of the clearance of the mesh and a diameter of the wires (di) that are expressed as a function of the structure diameter (D). The parameters "r" and "s" determine the degree of suppression of VIV.

Classes IPC  ?

• E21B 17/01 - Colonnes montantes pour têtes de puits immergées
• E02B 17/00 - Iles artificielles montées sur pilotis ou supports similaires, p.ex. plates-formes sur pieds extensibles; Procédés de construction de celles-ci
• F15D 1/10 - Action sur l'écoulement des fluides autour de corps formés d'un matériau solide

Abrégé

The present invention relates to a device and method for the preparation of platelet rich plasma, and to the plasma obtained by employing said device and method. The method comprises evaporating and dialysing plasma with the device of the invention to provide a plasma enriched in platelets and non-platelet biomolecules. The plasma thus obtained shows improved regenerative properties with respect to other plasma preparations.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c. à d. hémofiltration, diafiltration
• B01D 3/14 - Distillation fractionnée
• B01D 19/00 - Dégazage de liquides
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes

Abrégé

The present invention relates to a microfluidic device for the detection of circulating tumour cells (CTCs) in a fluid sample. The invention also relates to an in vitro method for the detection and/or quantification of circulating tumour cells (CTCs) in a fluid sample. Further, the invention relates to in vitro methods for (a) diagnosing a tumour and/or metastasis in a subject, and (b) determining the prognosis of a subject suffering from a tumour and/or metastasis. Finally, the invention refers to a kit comprising (a) a microfluidic device according to the first aspect of the invention, and (b) labelled probes targeting a first CTCs surface marker and, optionally, at least a second CTCs surface marker.

Classes IPC  ?

• G01N 15/14 - Recherche par des moyens électro-optiques
• G01N 15/10 - Recherche de particules individuelles
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
• C12N 5/09 - Cellules tumorales
• G01N 21/53 - Dispersion, c. à d. réflexion diffuse dans un corps ou dans un fluide dans un courant de fluide, p.ex. dans la fumée
• G01N 21/64 - Fluorescence; Phosphorescence
• G01N 21/65 - Diffusion de Raman
• G01N 33/574 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour le cancer

Abrégé

Disclosed is a non-therapeutic use of a sensor for detecting biological fluids in vitro, the sensor comprising a substrate coated with conductive ink, the substrate being inert relative to the conductive ink, the sensor comprising means for measuring conductivity or resistivity of the conductive ink, wherein the conductive ink comprises a carbon substrate and a surfactant. The sensor may also comprise a polymer such as a gum. Also disclosed are methods of detecting biological fluids and uses of the sensor.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/20 - Mesure des fonctions urologiques
• A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
• C09D 11/52 - Encres conductrices de l’électricité
• G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide

Abrégé

e) recognizing at least one defined SERS spectrum of the nanoparticle-analyte complex, through a SERS signal enhanced by the at least one narrow inter-nanoparticle gap.

Classes IPC  ?

• G01N 21/65 - Diffusion de Raman
• G01N 33/58 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des substances marquées
• G01N 33/574 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour le cancer
• B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p.ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires

Abrégé

The invention relates to a self-oscillating electronic ballast comprising: - a current inverter with switching devices (Q1, Q2); a resonant tank circuit connected to the output of the current inverter; a current detector circuit for detecting the current circulating through the resonant tank circuit; and a dimming control circuit and a ballast self-start control circuit that uses the ballast oscillation provided by the resonant tank circuit to control ballast self-starting. The system comprises: at least one ballast according to the present invention; a remote control device designed for generating a variable reference voltage signal and transmitting the signal to the ballast control circuit.

Classes IPC  ?

• H05B 41/38 - Commande de l'intensité de la lumière
• H05B 41/18 - Circuits dans lesquels la lampe est alimentée par courant continu ou par courant alternatif à basse fréquence, p.ex. courant alternatif à 50 Hertz ayant un commutateur de démarrage

Abrégé

1 are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer and a method of treating diabetes.

Classes IPC  ?

• C07D 493/08 - Systèmes pontés
• A61P 35/02 - Agents anticancéreux spécifiques pour le traitement de la leucémie
• C07D 487/08 - Systèmes pontés
• C07D 495/08 - Systèmes pontés
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p.ex. antidiabétiques

Abrégé

The present invention relates to a process for preparing a partially hydrogenated polyacene, and a novel intermediate used in such process; also the present invention relates to a process for preparing the corresponding conjugated polyacenes.

Classes IPC  ?

• C07C 41/30 - Préparation d'éthers par des réactions ne formant pas de liaisons sur l'oxygène de la fonction éther par augmentation du nombre d'atomes de carbone, p.ex. par oligomérisation
• C07D 333/16 - Radicaux substitués par des hétéro-atomes, autres que les halogènes, liés par des liaisons simples par des atomes d'oxygène
• C07D 333/50 - Composés hétérocycliques contenant des cycles à cinq chaînons comportant un atome de soufre comme unique hétéro-atome du cycle condensés avec des carbocycles ou avec des systèmes carbocycliques
• C07D 333/56 - Radicaux substitués par des atomes d'oxygène
• C07F 7/08 - Composés comportant une ou plusieurs liaisons C—Si
• C07C 41/18 - Préparation d'éthers par des réactions ne formant pas de liaisons sur l'oxygène de la fonction éther
• C07C 43/166 - Ethers non saturés contenant des cycles aromatiques à six chaînons avec une insaturation autre que celle des cycles aromatiques
• C07C 43/176 - Ethers non saturés contenant des atomes d'halogène contenant des cycles aromatiques à six chaînons avec insaturation autre que celle des cycles aromatiques
• C07C 43/21 - Ethers une liaison sur l'oxygène de la fonction éther étant sur un atome de carbone d'un cycle aromatique à six chaînons contenant des cycles autres que des cycles aromatiques à six chaînons
• C07C 43/215 - Ethers une liaison sur l'oxygène de la fonction éther étant sur un atome de carbone d'un cycle aromatique à six chaînons avec une insaturation autre que celle des cycles aromatiques à six chaînons
• C07C 1/20 - Préparation d'hydrocarbures à partir d'un ou plusieurs composés, aucun d'eux n'étant un hydrocarbure à partir de composés organiques ne renfermant que des atomes d'oxygène en tant qu'hétéro-atomes
• C07C 45/64 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogène; Préparation des chélates de ces composés par des réactions ne créant pas de groupe C=O par introduction de groupes fonctionnels contenant de l'oxygène lié uniquement par liaison simple
• C07C 45/65 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogène; Préparation des chélates de ces composés par des réactions ne créant pas de groupe C=O par hydrogénolyse de groupes fonctionnels
• C07C 45/68 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogène; Préparation des chélates de ces composés par des réactions ne créant pas de groupe C=O par modification de la taille du squelette carboné par augmentation du nombre d'atomes de carbone
• C07C 47/546 - Composés comportant des groupes —CHO liés à des atomes de carbone de cycles aromatiques à six chaînons polycycliques
• C07C 47/575 - Composés comportant des groupes —CHO liés à des atomes de carbone de cycles aromatiques à six chaînons contenant des groupes éther, des groupes , des groupes ou des groupes
• C07C 49/792 - Cétones comportant un groupe cétone lié à un cycle aromatique à six chaînons polycycliques contenant des cycles autres que des cycles aromatiques à six chaînons
• C07C 49/84 - Cétones comportant un groupe cétone lié à un cycle aromatique à six chaînons contenant des groupes éther, des groupes , des groupes ou des groupes
• C07C 13/62 - Hydrocarbures polycycliques ou leurs dérivés hydrocarbonés acycliques à cycles condensés à plus de trois cycles condensés
• C07C 13/66 - Hydrocarbures polycycliques ou leurs dérivés hydrocarbonés acycliques à cycles condensés à plus de trois cycles condensés le système cyclique condensé ne contenant que quatre cycles
• C07C 17/361 - Préparation d'hydrocarbures halogénés par des réactions comportant une diminution du nombre d'atomes de carbone
• C07C 25/22 - Hydrocarbures halogénés aromatiques polycycliques à cycles condensés

Abrégé

Compounds are of the formula (Ia), (Ib), (Ic), or are stereoisomers thereof, wherein: R1 is hydrogen, (C1-C20)alkyl; (C3-C20)alkenyl; (C3 C20)alkynyl; (C1-C6)alkyl-O—; (C3-C20)cycloalkyl; (C1 C20)haloalkyl; (C6-C20)aryl optionally substituted; (C6-C20)heteroaryl optionally substituted; R2 and R2′ are hydrogen; (C1-C20)alkyl; (C1-C6)alkyl-O—; (C1-C6)haloalkyl; halogen; cyano; and nitro; Z1 to Z4 are diradicals of formula (III) wherein A1 and A2 are O— or NR3-, wherein R3 is selected from the group consisting of hydrogen and (C1-C20)alkyl; and G is (C1-C6)alkyl; —P(═S)R5-; —P(═O)R4; —P(═O)(OR4)-; —P(═O)(NR6R7)-; —S(═O)2-; S(═O)—; or —C(═O)—; and Y1 to Y4 are (C1-C8)alkyl; (C3-C7)cycloalkyl; (C6-C20)aryl optionally substituted; or (C6-C20)heteroaryl optionally substituted; and FG1 and FG2 are H, OH, or NHR8.

Classes IPC  ?

• G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
• G01N 33/70 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir la créatine ou la créatinine
• C07D 403/14 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant au moins trois hétérocycles
• C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
• B01J 39/16 - Substance organique
• C07D 491/22 - Composés hétérocycliques contenant dans le système cyclique condensé, à la fois un ou plusieurs cycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle, et un ou plusieurs cycles comportant des atomes d'azote comme uniques hétéro- dans lesquels le système condensé contient au moins quatre hétérocycles
• C07F 9/6571 - Composés hétérocycliques, p.ex. contenant du phosphore comme hétéro-atome du cycle comportant des atomes de phosphore, avec ou sans atomes d'azote, d'oxygène, de soufre, de sélénium ou de tellure, comme hétéro-atomes du cycle comportant des atomes de phosphore et d'oxygène comme uniques hétéro-atomes du cycle
• C08J 5/22 - Bandes, membranes ou diaphragmes
• C08K 5/32 - Composés contenant de l'azote lié à l'oxygène
• C08K 5/5373 - Esters des acides phosphoniques contenant des hétérocycles ne représentant pas des esters cycliques des acides phosphoniques
• C08K 5/55 - Composés contenant du bore
• G01N 27/40 - Membranes ou cloisons semi-perméables

Abrégé

A computer implemented method of generation of statistically uncorrelated molecule's conformations and computer programs The method is executed in a computer system equipped with GPU and comprises using a parallel version of Rosenbluth method implemented of said GPU, wherein parallelization being achieved by generating each molecules conformation in individual thread of a stream processing in the GPU, wherein said stream processing starts with the initialization of the GPU and the initialization of a random generator for the GPU, so that each thread of the stream processing generates statistically uncorrelated random numbers, and each thread of the stream processing is performed simultaneously and synchronously generating its own statistically uncorrelated molecule conformation.

Classes IPC  ?

• G06F 19/00 - Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des applications spécifiques (spécialement adaptés à des fonctions spécifiques G06F 17/00;systèmes ou méthodes de traitement de données spécialement adaptés à des fins administratives, commerciales, financières, de gestion, de surveillance ou de prévision G06Q;informatique médicale G16H)

Abrégé

The present invention relates to a method for obtaining an enzymatic hydrolysate with antihypertensive activity which comprises grinding chicken feet and lyophilizing to obtain a powder material having a particle size <2 mm; adjusting an aqueous solution of this powder to a pH different from the pH of the starting powder by a value of 0.5 and heating between 80 and 120°C for between 10 and 120 min; cooling the preceding solution to a temperature between 45 and 55°C and performing enzymatic hydrolysis for a time between 1 and 24 h with selected enzymes, evaluating and selecting the angiotensin-converting enzyme inhibitory activity. The invention also relates to the use of the hydrolysate that is obtained in the treatment of hypertension, and the pharmacological use of the peptides containing the hydrolysate.

Classes IPC  ?

• A61K 35/32 - Os; Ostéocytes; Ostéoblastes; Tendons; Ténocytes; Dents; Odontoblastes; Cartilage; Chondrocytes; Membrane synoviale
• A61K 35/36 - Substances provenant de mammifères; Compositions comprenant des tissus ou des cellules non spécifiés; Compositions comprenant des cellules souches non embryonnaires; Cellules génétiquement modifiées Épiderme; Cellules épithéliales; Kératinocytes; Cellules de Langerhans; Cellules ectodermiques
• A61P 9/12 - Antihypertenseurs

Abrégé

A method and a system for detection of presence or absence of analytes in fluids, the method comprising the steps of: a) contacting a fluid sample and a plurality of nanoparticles, the nanoparticles being functionalized with a selective ligand, the contact of the fluid sample with the nanoparticles being under conditions such that, the nanoparticles aggregate selectively on surface of their target analyte, forming a nanoparticle-analyte complex, the aggregation promoting the concentration of the nanoparticles on the surface of the target analyte; b) subjecting a fluid mixture of the fluid sample and the plurality of nanoparticles to SERS; c) measuring at least a SERS signal associated with the fluid mixture; d) spectrally analysing the at least one SERS signal of step c); e) recognizing at least one defined SERS spectrum of the nanoparticle-analyte complex, through a SERS signal enhanced by the at least one narrow inter-nanoparticle gap.

Classes IPC  ?

• G01N 21/65 - Diffusion de Raman
• B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p.ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
• C12Q 1/04 - Détermination de la présence ou du type de micro-organisme; Emploi de milieux sélectifs pour tester des antibiotiques ou des bactéricides; Compositions à cet effet contenant un indicateur chimique

Abrégé

Disclosed is a compound of formula (I) in which R1-R5 and X1 are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer and a method of treating diabetes.

Classes IPC  ?

• C07D 487/08 - Systèmes pontés
• A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
• A61P 35/00 - Agents anticancéreux
• C07D 493/08 - Systèmes pontés
• C07D 495/08 - Systèmes pontés

Abrégé

The invention relates to a composition for the cross-linking of an amine with a vinyl compound α,β-conjugated to a carbonyl group of esters, and subsequent polymerisation of the vinyl compound, comprising: a) an amine having two or more N-H bonds; b) a vinyl compound, of general formula (I), containing a minimum of two double bonds α,β-conjugated to a carbonyl group of esters - formula (I) - where Y and Z are each independently a hydrogen, aliphatic or aromatic groups or more complex groups, and where X is an aliphatic or aromatic group or a more complex group; and c) a radical photoinitiator or a radical thermal initiator, suitable for starting the cross-linking of said double bonds excess α,β-conjugated to a carbonyl group of esters.

Classes IPC  ?

• C08G 73/02 - Polyamines
• C08K 5/16 - Composés contenant de l'azote
• C09D 133/06 - Homopolymères ou copolymères d'esters d'esters ne contenant que du carbone, de l'hydrogène et de l'oxygène, l'atome d'oxygène faisant uniquement partie du radical carboxyle
• C08F 220/10 - Esters

Abrégé

Disclosed is a compound of formula (I) in which R1-R5 and X1 are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer and a method of treating diabetes.

Classes IPC  ?

• C07D 487/08 - Systèmes pontés
• C07D 493/08 - Systèmes pontés
• C07D 495/08 - Systèmes pontés
• A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
• A61P 35/00 - Agents anticancéreux

Abrégé

These compounds are of formula (la), (lb), (Ic), or are stereoisomers thereof, wherein: R1 is hydrogen, (C1-C20)alkyl; (C3-C20)alkenyl; (C3-C20)alkynyl; (C1- C6)alkyl-O-; (C3-C20)cycloalkyl; (C1-C20)haloalkyl; (C6-C20)aryl optionally substituted; (C6-C20)heteroaryl optionally substituted;; R2 and R2' are hydrogen; (C1-C20)alkyl; (C1-C6)alkyl-O-; (C1-C6)haloalkyl; halogen;cyano; and nitro; to Z1 to Z4 are diradicals of formula (III) wherein A1 and A2 are -O- or -NR3-, wherein R3 is selected from the group consisting of hydrogen and (C1- C20)alkyl; and G is (C1-C6)alkyl;;-P(=S)R5-; -P(=O)R4; -P(=O)(OR4)-; - P(=O)(NR6R7)-; -S(=O)2-; -S(=O)-; or -C(=O)-; and Y1 to Y4 are (C1-C8)alkyl; (C3-C7)cycloalkyl; (C6-C20)aryl optionally substituted; or (C6-C20)heteroaryl optionally substituted; and FG1 and FG2 are H, OH, or NHR8. These compounds are useful as ionophores for creatinine quantification.

Classes IPC  ?

• C07D 403/14 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant au moins trois hétérocycles
• C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
• G01N 27/333 - Electrodes ou membranes sélectives à l'égard des ions

Abrégé

The resistive sensor A includes a support with electrodes covered with carbon nanotubes that are functionalised and decorated with metal nanoparticles, the metal nanoparticles thereof supporting a single layer of an organic compound of the group resorcin[4]arene. The invention also relates to a device comprising said resistive sensor A and a resistive sensor B, which is identical to sensor A except that it does not include an organic compound, in order to selectively detect, with increased sensitivity, benzene gas in air. The device is reversible. The method for producing the resistive sensor A comprises selecting a support, designing electrodes, treating the nanotubes with oxygen, decorating them with metal nanoparticles, depositing the nanotubes on the electrodes, preparing a solution of the organic compound and submerging the support in said solution in order to form a single layer of the organic compound.

Classes IPC  ?

• G01N 27/04 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance
• C07D 493/22 - Composés hétérocycliques contenant des atomes d'oxygène comme uniques hétéro-atomes dans le système condensé dans lesquels le système condensé contient au moins quatre hétérocycles
• C07D 491/22 - Composés hétérocycliques contenant dans le système cyclique condensé, à la fois un ou plusieurs cycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle, et un ou plusieurs cycles comportant des atomes d'azote comme uniques hétéro- dans lesquels le système condensé contient au moins quatre hétérocycles
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites

Abrégé

The invention relates to an aggregate comprising metallic nanoparticles and nucleic acid molecules wherein each metallic nanoparticle is coated with a polycation. The invention also relates to a method for obtaining the aggregate of the invention and to the use of said aggregate in methods for detecting the presence of a nucleic acid in a sample, in methods for detecting the presence of a given nucleotide at a predetermined position in a target nucleic acid, in methods for detecting the presence of a modified nucleotide at a predetermined position in a target nucleic acid, methods for detecting the presence of a conjugate between a double stranded nucleic acid and a chemical in a sample comprising double stranded nucleic acid molecules, in methods for determining the content of modified nucleotides in a target nucleic acid and in a method for determining the content of modified nucleotides in a target nucleic acid.

Classes IPC  ?

• B82Y 5/00 - Nanobiotechnologie ou nanomédecine, p.ex. génie protéique ou administration de médicaments
• B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p.ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques

Abrégé

The invention relates to the use of an extract comprising proanthocyanidins, in the gallated or non-gallated form, together with gallated procyanidins, for producing a solution and/or other forms of administration suitable for suppressing appetite or inducing satiation, wherein said proanthocyanidins do not include proanthocyanidins formed solely by gallated (epi)catechin units.

Classes IPC  ?

• A23L 33/20 - Diminution de la valeur nutritive; Produits diététiques avec valeur nutritive réduite

Produits et services

Testing apparatus not for medical purposes; Scientific apparatus and instruments; Multi-headed instruments for redistributing, organising, archiving, publishing and analysing the results of research projects in computational chemistry; Chemical analysis apparatus not for medical purposes; Computer software; Data processing equipment; Weighing, measuring, checking (supervision) and teaching apparatus and instruments; Computer programs; Computer operating programs, recorded; Computer software for managing of databases for research and results in computational chemistry; Computer databases. Scientific and technological services and research and design relating thereto; Industrial analysis and research services; Design and development of computer hardware and software; Scientific research relating to chemistry, Biochemistry research services, Research relating to biotechnology, Research laboratories, Physics [research], Research and development of new products, Preparation of reports relating to chemical research, Chemical research and analysis services.

Abrégé

The invention relates to a a remote temperature measurement device comprising: an infrared light source where the source of illumination is arranged so as to illuminate luminescent particles, the luminescence emission thereof depending on the temperature; a system of lenses for focusing the infrared light source; an RGB colour sensor arranged so as to detect the emission of the luminescent particles and to simultaneously supply a first signal in a first wavelength region and a second signal in a second wavelength region; a filter for separating the reflection of the source of illumination of infrared light from the emission of the luminescent particles; and a processing unit designed to calculate a value of a ratio between the first signal and the second signal supplied by the RGB colour sensor and to determine the temperature. The invention also relates to a method for remote temperature measurement.

Classes IPC  ?

• G01K 11/20 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant des matériaux thermo-luminescents

Abrégé

A silicon particle comprising a silicon body, a functionalized silica surface surrounding the silicon body, and a targeting moiety specifically targeting tumor cells, and, optionally, an enzymatically metabolizable compound,is useful in the treatment of cancer by producing cell death after particle internalization.

Classes IPC  ?

• A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
• A61P 35/00 - Agents anticancéreux

Abrégé

An in vitro method for the characterization of lipoproteins in a sample, comprising obtaining a 2D diffusion-ordered 1H NMR spectrum of the sample and performing a surface fitting of a portion of the spectrum corresponding to the methyl signal using a plurality of model functions, each model function corresponding to a given particle size associated to a lipoprotein fraction and subclass and including at least one model parameter to be estimated during the fitting, the estimated model parameters being the set of model parameters for which the difference between the NMR signal and the model signal built as a linear combination of the model functions is minimized,wherein each model function is a triplet of lorentzian functions.

Classes IPC  ?

• G01N 33/92 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des lipides, p.ex. le cholestérol
• G01N 24/08 - Recherche ou analyse des matériaux par l'utilisation de la résonance magnétique nucléaire, de la résonance paramagnétique électronique ou d'autres effets de spin en utilisant la résonance magnétique nucléaire
• G01R 33/465 - Spectroscopie RMN appliquée à du matériau biologique, p.ex. tests in vitro

Abrégé

An in vitro method for the characterization of lipoproteins in a sample, comprising obtaining a 2D diffusion-ordered 1H NMR spectrum of the sample and performing a surface fitting of a portion of the spectrum corresponding to the methyl signal using a plurality of model functions, each model function corresponding to a given particle size associated to a lipoprotein fraction and subclass and including at least one model parameter to be estimated during the fitting, the estimated model parameters being the set of model parameters for which the difference between the NMR signal and the model signal built as a linear combination of the model functions is minimized,wherein each model function is a triplet of lorentzian functions.

Classes IPC  ?

• G01N 33/92 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des lipides, p.ex. le cholestérol
• G01R 33/465 - Spectroscopie RMN appliquée à du matériau biologique, p.ex. tests in vitro
• G01N 24/08 - Recherche ou analyse des matériaux par l'utilisation de la résonance magnétique nucléaire, de la résonance paramagnétique électronique ou d'autres effets de spin en utilisant la résonance magnétique nucléaire

Abrégé

A method for calculating the distribution of triglycerides and cholesteryl esters between the core and the shell of a lipoprotein particle that transports cholesterol, triglycerides and other lipids is provided based on the comparison between the shell and core volume ratios calculated by two different methods. For use in biomedicine.

Classes IPC  ?

• G01N 33/92 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des lipides, p.ex. le cholestérol

Abrégé

The present invention relates to a method for the identification of a plurality of target analytes present in a fluid which comprises: (a) contacting a sample of said fluid comprising a plurality of target analytes with a set of different nanoparticles, wherein each of said nanoparticles comprises a core coated by a coating, wherein said coating comprises a Raman code and a ligand for each target analyte, under conditions allowing the interaction between said target analyte and its ligand and the formation of a target analyte/ligand complex, and (b) subjecting the resulting mixture to surface enhanced Raman spectroscopy (SERS), and analyzing the Raman spectra associated with the target analyte-ligand complexes formed and thereafter identifying the target analytes present in said fluid.

Classes IPC  ?

• G01N 33/543 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
• G01N 33/53 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet
• G01N 21/65 - Diffusion de Raman

Abrégé

The invention relates to a method characterised in that it comprises a first step of placing a calibration standard in front of the camera; in a second step, a sequence of images is captured by focusing the camera at different distances around the position of the standard; an intensity profile for the grey levels is extracted from each image of the calibration standard; for each profile, l(x) obtained, a value is estimated for the defocusing radius ρ, by adjusting the equation (1) to the corresponding profile: (1) where erf is the error function: (II) and the value of the camera constant is obtained by adjusting the curve of the values of the defocusing radius ρ according to the values of u, according to the following equation: (III).

Classes IPC  ?

• G03B 13/32 - Moyens de mise au point
• H04N 5/00 - TRANSMISSION D'IMAGES, p.ex. TÉLÉVISION - Détails des systèmes de télévision

Abrégé

The invention relates to an optical sensor for detecting the presence of ice on surfaces, characterised in that it comprises: a waveguide having an optical coating with a refractive index that fulfills the relation nwater ≤ nmaterial ឬ nice at a wavelength λT for which nwater ឬ nice, and a core contained in the coating and suitable for propagating an optical signal of λT, the waveguide having a sensor segment that is installed on a surface with one face of the coating exposed; means for injecting an optical signal of λT into the waveguide; and means for detecting the optical signal transmitted by the waveguide downstream of the sensor segment. The sensor detects the formation of ice, differentiating same from the presence of water. The sensor is resistant to erosion and can be mounted without projecting from the surface.

Classes IPC  ?

• B64D 15/20 - Dispositifs pour détecter le givrage ou amorcer la mise en action du dégivrage
• G08B 19/02 - Alarmes réagissant à la formation ou à la formation escomptée de la glace

Abrégé

The invention relates to a rheometer (1) comprising at least one rectilinear capillary (2) provided with visual graduations and a space (3) for receiving a sample of fluid, the rheological behavior of which is to be determined, wherein the receiving space (3) is arranged at an end of said capillary (2) and wherein said capillary (2) is arranged horizontally, the other end of the capillary being open such that when the fluid is in said receiving space (3), it is sucked out by capillarity, allowing the speed of advancement of the fluid to determine the rheological behavior thereof corresponding to the diameter of the capillary (2).

Classes IPC  ?

• G01N 11/04 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en mesurant l'écoulement du matériau à travers un passage étroit, p.ex. un tube, une ouverture

Abrégé

The invention relates to a cisgenic and homozygous strain of rats with double gene doping of MCP-1, which overproduce MCP-1, present in both somatic 5 cells and germ cells, containing, in the genome thereof, a mouse gene mcp-1 preferably introduced by means of transgenesis or intragenesis, and progenies and derived cell lines. The invention also relates to the method of obtaining and using same.

Classes IPC  ?

• A01K 67/027 - Nouvelles races de vertébrés
• C07K 14/52 - Cytokines; Lymphokines; Interférons
• C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales

Abrégé

The invention relates to a push device (1) for a piston (2) of a hydraulic clutch, comprising an element (3) for pushing the piston (2), comprising a pre-compressed spring (4) that presses the push element (3) against the piston (2), an endless screw (5) for pulling the push element (4) away from the piston, and an electric motor (6) for the rotary actuation of the endless screw (5), such that, without needing to modify the system into which it is incorporated, it allows the total or partial automation of a clutch or brake actuated by the piston.

Classes IPC  ?

• F16D 29/00 - Embrayages ou systèmes d'embrayages comportant un actionnement par fluide et un actionnement magnétique ou comportant un actionnement par fluide et un actionnement électrique

Abrégé

Rechargeable electrical voltage supply system which comprises a battery (1.1) provided with a plurality of cells (CAX1, CAX2,... CAXP) connected in series, a voltage output (Vo) for a load (2), a voltage input (VI) for recharging, a first converter module (3) arranged between the battery (1) and the output (Vo), sensors (5) for physical variables of the battery (1) which reflect the state of charge of the latter, which comprises controlled bypass circuits (EMUAX1, EMUAX2,... ΕΜUAXn) for the cells (CAX1, CAX2,... CAXn), and a device for managing the battery (6) of the circuits (EMUAX1, EMUAX2,... EMUAXn), which device receives signals from the sensors (5) such that it is possible to balance the state of charge of the cells (CAX1, CAX1,... CAXn), obtaining a variable voltage (Vint) at the output of the battery (1), which voltage may be adapted to the voltage output (Vo) by means of the first converter (3).

Classes IPC  ?

• H01M 10/42 - Procédés ou dispositions pour assurer le fonctionnement ou l'entretien des éléments secondaires ou des demi-éléments secondaires
• H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries

Abrégé

The invention relates to an MPPT method and circuit (31) for tracking the MPP, using a phase processing unit (PPU) that generates, with a potentially elevated resampling frequency, a first resampling signal cos(ωditht) and a second resampling signal cos(ωditht+ φ) dephased at a variable angle φ in order to obtain a signal (u) for acting on a commutated converter (12) of a photovoltaic system (30). The invention also includes a digital integrator (23) that generates an output signal (d) from a high-pass digital filter signal (21) in the MPPT circuit (31) and the second sampling signal cos(ωditht+ φ) that pass through a multiplier (22) at the inlet of the digital integrator (23), and an adder (24) that adds the output signal (d) of the digital integrator (23) to the first resampling signal cos(ωditht) in order to obtain the actuation signal (u). The unit (PPU) comprises an estimator (51) of the phase difference φconv in the commutated converter (12), which, in turn, comprises an estimator of the incremental resistance RA and an estimator (52) of the phase difference φfd produced in the high-pass digital filter (21), that are added together to obtain the angle φ.

Classes IPC  ?

• G05F 1/67 - Régulation de la puissance électrique à la puissance maximale que peut fournir un générateur, p.ex. une cellule solaire

Abrégé

The invention relates to a station for measuring environmental gamma radiation with a detector (5) capable of performing gamma spectrometry, placed opposite a continuous paper filter (2). Discharging a predetermined volume of air onto the filter via a suction pump makes it possible to increase the concentration of radioactive isotopes near the detector (4), such that the identification of the gamma isotopes and quantification of the activity concentration thereof is more precise, reducing the minimum detectable activity.

Classes IPC  ?

• G01T 1/202 - Mesure de l'intensité de radiation avec des détecteurs à scintillation le détecteur étant du cristal

Abrégé

Each member in the group has an individually identifiable computing device with telecommunications capability, and the method proposes contactless interaction with the computing devices from a control centre, establishing conditions for a transaction, and determining the number of members by acquiring and counting a total number of partial digital signatures carried out by the members by means of a computer application in the computing device thereof which implements an identity-based digital signature scheme with a dynamic threshold, guaranteeing the anonymity of the members in the group. The system comprises the computing devices with an installed computer application, an accreditation station with means for interacting with the devices and a certification authority.

Classes IPC  ?

• G06Q 20/00 - Architectures, schémas ou protocoles de paiement

Abrégé

Method for carrying out transactions with digital banknotes. The method is applicable to digital banknotes provided with an identifier, a validity test and an item of information relating to a usage right associated with said digital banknote, comprising the following steps: a. a proprietary user UP sends a transaction offer for the digital banknote; b. a receiving user UR verifies the validity test of said digital banknote; c. a transfer request from said UR to said UP is generated; d. said UP verifies said transfer request and said UP generates a transfer acceptance; e. said UR verifies said transfer acceptance; and f. the digital banknote is transferred to the UR who acquires the usage right.

Classes IPC  ?

• G06Q 20/04 - Circuits de paiement
• G07B 15/00 - Dispositions ou appareils pour encaisser le prix des billets ou les droits d’entrée ou de péage en un ou plusieurs points de contrôle

Abrégé

Station for measuring radiation with two lead-screened gamma spectrometry detectors, allowing the identification of gamma-radioactive isotopes in the environment and real-time quantification of the gamma activity concentration in the case of individual isotopes. A first crystal (1) is covered with lead screening (3) in the upper and lateral part thereof and a second crystal (2) is covered by further lead screening (3) in the lower and lateral part thereof. The dual probe with screening makes it possible to distinguish between radiation originating from the upper or lower part and to prevent interference in the measurement.

Classes IPC  ?

• G01T 1/202 - Mesure de l'intensité de radiation avec des détecteurs à scintillation le détecteur étant du cristal
• G01T 1/36 - Mesure de la distribution spectrale des rayons X ou d'une radiation nucléaire

Abrégé

The invention relates to the field of molecular biology techniques, in particular to the polymerase chain reaction (PCR). More specifically, the invention relates to a primers specially designed for the PCR and to the direct detection of a target sequence. This is achieved owing to the special design of the primer and, more specifically, owing to the presence of single-strand tails in the amplification product obtained using said primers. These tails allow the capture of the amplification product on a functionalised substrate with capture probes and/or the simple detection thereof with reporter probes.

Classes IPC  ?

• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques

Abrégé

A particle image velocimetry method for measuring the velocity of a fluid by means of seeding the fluid with tracer particles and recording the light reflected at two different moments in time, wherein the tracer particles are particles of alginate. This method may be used in systems with metal parts in contact with one another, since no damage will be caused thereto. The particles are spherical and, furthermore, non-toxic and non-harmful to the environment; moreover, as the particles are porous, the density thereof may be matched easily with that of the fluid for effective monitoring thereof.

Classes IPC  ?

• G01N 21/85 - Analyse des fluides ou solides granulés en mouvement

Abrégé

The invention relates to a device for cooling by single-stage absorption, in which the working fluid is a ternary mixture of ammonia/lithium nitrate and water, wherein: the coolant is the ammonia; and the absorbent is the solution of lithium nitrate and water; characterised in that the moisture content of the output vapour of the generator is less than 1%, such that no rectifier is required.

Classes IPC  ?

• F25B 15/04 - Machines, installations ou systèmes à sorption, à marche continue, p.ex. à absorption sans gaz inerte le frigorigène étant de l'ammoniac évaporé d'une solution aqueuse
• F25B 25/00 - Machines, installations ou systèmes utilisant une combinaison des principes de fonctionnement compris dans plusieurs des groupes
• C09K 5/04 - Substances qui subissent un changement d'état physique lors de leur utilisation le changement d'état se faisant par passage de l'état liquide à l'état vapeur ou vice versa

Abrégé

The voltage-sensing circuit structure is intended to avoid fast-scale subharmonic instabilities in switching power converters, comprising a compact circuit structure to be connected at the output of a switching power converter, by means of which the sensed feedback voltage is altered with a double transfer function so that concurrently the ripple component is amplified to obtain an enhanced fast- scale stability margin while attenuating the converter output voltage ripple in the power path.

Classes IPC  ?

• H02M 3/156 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p.ex. régulateurs à commutation
• H03F 3/217 - Amplificateurs de puissance de classe D; Amplificateurs à commutation
• G06G 7/161 - Dispositions pour l'exécution d'opérations de calcul, p.ex. amplificateurs spécialement adaptés à cet effet pour la multiplication ou la division avec modulation d'impulsions, p.ex. modulation d'amplitude, de largeur, de fréquence, de phase ou de forme

Abrégé

The invention relates to a switched power supply (1) intended to function in interlace mode, that includes CC-CC converters (Ci) in parallel, each one provided with a controlled switch (Ii), in which the switched state of each converter (Ci) is controlled as a function of a signal generated by the adjacent converter (Ci+1) and in which the first (C1) is controlled by a signal generated by the last converter (Cn), such that the converters (Ci) are arranged in a ring configuration, characterized in that it includes a means for establishing the maximum intensities (Imaxi) and minimum intensities (Imini) that determine the change from closed to open and from open to closed for the controlled switches (Ii) of each converter (Ci) as a function of the signal generated by the adjacent converter (Ci+1), such that the device can operate in interlace mode.

Classes IPC  ?

• H02J 1/10 - Fonctionnement de sources à courant continu en parallèle
• H02M 3/156 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p.ex. régulateurs à commutation
• H03K 4/06 - Génération d'impulsions ayant comme caractéristique essentielle une pente définie ou des parties en gradins à forme triangulaire

Abrégé

The invention relates to a DC/DC up-converter (1) comprising: a voltage source (Vs), a coil (L) and a diode (D) arranged in series, the input terminal of the coil being connected to the voltage source and the output terminal of the diode being connected to a load (Vo); a capacitor (C) disposed in parallel with the load (Vo); and a controlled switch (T) disposed with a terminal between the coil (L) and the diode (D), such as to allow the voltage (Vs) to be applied to the coil (L) when closed. The invention also includes means for controlling the controlled switch (T), configured to: switch same from a closed state to an open state when the current (IL) passing through the coil exceeds an upper threshold current (Is), and to switch same from an open state to a closed state when the current passing through the coil drops below a lower threshold current (Ii).

Classes IPC  ?

• H02M 3/02 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif

Abrégé

The invention relates to a composition for cross-linking an epoxy resin with an isocyanate, which includes: an epoxy resin, a polyisocyanate, and a rare earth triflate, where the rare earth is chosen from the group consisting of Scandium, Yttrium, Lanthanum, Cerium, Praseodymium, Neodymium, Promethium, Samarium, Europium, Gadolinium, Terbium, Dysprosium, Holmium, Erbium, Thulium, Ytterbium and Lutetium. The invention further relates to a method for obtaining said composition, to a method for cross-linking the epoxy resin with the polyisocyanate, which includes putting the components in contact and heating same, and to the resulting cross-linked material.

Classes IPC  ?

• C08G 18/00 - Polymérisats d'isocyanates ou d'isothiocyanates
• C08G 59/40 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les agents de durcissement utilisés
• C08G 59/68 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les catalyseurs utilisés

Abrégé

Device for the selective detection of benzene gas, which comprises, on a base substrate, a combination of at least one functionalised multi- or single-wall carbon nanotube sensor decorated with rhodium clusters, and at least one functionalised multi- or single-wall carbon nanotube sensor decorated with metal clusters selected from gold, palladium, nickel and titanium, and/or undecorated, where said substrate additionally comprises means for measuring the variation in the resistance of said sensors. The device is useful at ambient temperature in the presence or absence of oxygen and easy to handle. It also relates to a method for the manufacturing thereof and for detecting the gas in the chemical industry, the petrochemical industry, petrol stations, or household, aeronautical or research applications.

Classes IPC  ?

• G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide

Abrégé

Micro fluidic devices comprising three dimensional elements fabricated onto a substrate using thick film printing technology, e.g., screen printing, wherein the three dimensional elements possess both structural and functional properties.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes

Produits et services

Paper, cardboard and goods made from these materials, not included in other classes; printed matter; bookbinding material; photographs; stationery; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching material (except apparatus); plastic materials for packaging (not included in other classes); printers' type; printing blocks. Transport, storage and distribution of products; arrangement of tours and travel; transportation of passengers. Education; providing of training; arranging and conducting of symposiums, seminars, colloquiums, conferences and congresses; entertainment; sporting and cultural activities; publication of texts [other than publicity texts]; educational examination.

Abrégé

The invention relates to a motor comprising a framework (1) housing at least one stator (7a) and an actuator (8) mobile in relation to an axis X, configured in such a way as to adopt a magnetic coupling arrangement integrating the actuator (8), and a series of poles (12) that are perpendicular to the axis X and can oppose a series of poles (10a) of the stator (7a) during movement, said stator carrying excitation electromagnets (9a). Eyelets (15) are arranged in posts of the framework (1), for varying a distance "d" between the poles (10a) of the stator (7a) and the poles (12) of the actuator (8), thereby modifying the reluctance of the motor. Said actuator (8) comprises a plurality of plates (18) enclosed between sliding lateral bars (19) by guides (13) of the framework and end pieces (22) comprising members (23) for connecting to the device to be actuated.

Classes IPC  ?

• H02K 41/03 - Moteurs synchrones; Moteurs pas à pas; Moteurs à réluctance

Abrégé

The invention relates to a composition comprising a combination of a dimer-galate and a trimer, useful as a medicament for the treatment and/or prevention of metabolic syndrome or of a pathology associated therewith, wherein the dimer-galate is a procyanidin B-galate, differing from B2-galate, and the trimer is a procyanidin C. Furthermore it relates to the use of said composition in the preparation of a food, a food additive or a dietetic supplement.

Classes IPC  ?

• A61K 31/353 - 3,4-Dihydrobenzopyranes, p.ex. chromane, catéchine
• C07D 311/62 - Benzo [b] pyrannes non hydrogénés dans le carbocycle avec des substituants autres que des atomes d'oxygène ou de soufre en position 2 ou 4 avec des radicaux aryle liés en position 2 avec des atomes d'oxygène liés directement en position 3, p.ex. anthocyanidines
• A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme

Abrégé

The method according to the present invention makes it possible to obtain information associated with a location (3) using of a telecommunications device (2) and a two-dimensional code (1) where the information is stored. The information obtained relates to the geographical position of the two-dimensional code (1), that is to say the location (3), as well as to additional data such as a description of the location, a contact telephone number or the opening hours thereof. The information may be presented according to the language preferences of the user, with the two-dimensional code (1) having at least three languages and with it being possible to access a repository with a greater number of options or else to translate the content if the repository does not contain the translation in any of the selected languages. The translation is obtained by accessing the repository with a unique key which includes data relating to the geographical position of the location (3).

Classes IPC  ?

• G06F 17/22 - Manipulation ou enregistrement au moyen de codes, p.ex. dans une séquence de caractères de texte

Abrégé

In an LSRM equipped with a stator or primary winding and an actuator or secondary winding, which is movable relative to an axis x, which are configured in order to be in a mutual magnetic coupling configuration, the method comprises arranging concave three-dimensional surfaces obtained from computing, for each bp and bs pair, the resultant force from applying a certain minimum excitation electric current density (J) for a certain number of intermediate positions of the actuator, spaced by intervals inc_x of displacement of said actuator, the higher zone of said surface expressing the optimum force zone on the basis of said three-dimensional surfaces, and for different values of J, within operating limits, an optimum configuration of the device in terms of the variables bp and bs thereby being obtained.

Classes IPC  ?

• H02K 41/03 - Moteurs synchrones; Moteurs pas à pas; Moteurs à réluctance

Abrégé

Microfluidic device for rapid isolation of a compound or component contained in a sample together with other components, comprising in a matrix material a sample inlet (5) for introducing said sample, a first electrolyte reservoir (1) and a second electrolyte reservoir (2), comprising a first and second electrode, said electrodes embracing the first separation means, comprising a membrane (4), which membrane has a first and a second side, wherein a sample reservoir (3) is located adjacent to the first side of said membrane (4), a third electrolyte reservoir (6), comprising a third electrode, embracing with said first electrode and second separation means capable of separating said component from the other components of said sample, that separation means having an inlet and an exit, whereby said inlet is connected to said sample reservoir (3) by a duct comprising a valve (9) and said exit is connected to an opening (7) and via a duct to said third electrolyte reservoir (6). With said device a component contained in a sample can be isolated from other components by introducing said sample into said device and applying a first electrical potential between the first and second electrode, whereby said membrane retains the component to be isolated and concentrates it over said membrane in a sample trapping reservoir. After turning off the first electrical potential a duct connecting the sample trapping reservoir with separation means is opened and an electric potential in a second electric circuit between the first electrode and the third electrode is applied. Thereby a flux transporting the components from the sample trapping reservoir through said separation means is generated and the isolated components after their passage through the separation means are recovered.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
• G01N 1/00 - Echantillonnage; Préparation des éprouvettes pour la recherche
• G01N 27/447 - Systèmes utilisant l'électrophorèse
• G01N 30/00 - Recherche ou analyse de matériaux par séparation en constituants utilisant l'adsorption, l'absorption ou des phénomènes similaires ou utilisant l'échange d'ions, p.ex. la chromatographie

Abrégé

The present invention relates to a composition for removing gliadins and glutanins, which are prolamins that are toxic to patients suffering from coeliac disease, contained in heat-processed and non-heat-processed foods. The composition of the invention comprises a reducing agent for irreversible reduction of disulphide bridges and a solvent with a high boiling point and/or high dielectric constant in a buffer with a pH between 4 and 9. The invention also relates to the method for removing gluten (gliadins and glutenins) from food products, which is compatible with an enzyme-linked immunosorbant assay (ELISA), that allows detection of hydrolized and non-hydrolized gluten (gliadins and glutenins). Lastly, the invention relates to a kit for implementing said method.

Classes IPC  ?

• C07K 1/14 - Extraction; Séparation; Purification

Produits et services

Education, providing of training, arranging and conducting of colloquiums, congresses, symposiums, conferences, seminars, training workshops; publication of texts and publication of electronic books and journals on-line, all the aforesaid relating to conservation and environmental studies. Scientific and technological services and research and design relating thereto; industrial analysis and research services; design and development of computer hardware and software; architecture and interior decorating, in particular relating to the application of environmental sustainability criteria; planning of buildings and their infrastructure; research in the environmental field; consultancy in relation to planning and environmental protection; designing of buildings subject to environmental control; protection of the environment; town planning; consultancy relating to energy saving, conservation and optimisation in buildings; energy auditing services; quality control of buildings; management of architectural projects, technical architectural and engineering project studies and drafting of reports relating thereto; architectural consultation services; surveying; material testing; producing of drawings for appropriate maintenance and insulation of buildings; issuing of certificates relating to the energy efficiency of buildings. Legal services, in particular in the environmental field; preparation of contracts (legal services); consultancy, providing information and management of legal formalities relating to legal issues.