CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
Inventeur(s)
Verdel, André
Todeschini, Leïla
Perazza, Daniel
Abrégé
A method for purifying a protein of interest includes the preparation of a fusion protein in which this protein of interest is fused to a protein tag having the protein Mmi1 of a microorganism of the genus Schizosaccharomyces or a fragment thereof, the bringing into contact of this fusion protein with a ribonucleic acid molecule containing at least one motif of UNAAAC nucleotide sequence, so as to allow the affinity binding of the protein tag with this ribonucleic acid molecule, and the recovery of the protein of interest.
COMMISSARIAT A L’ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
ECOLE NATIONALE SUPERIEURE DES ARTS ET INDUSTRIES TEXTILES (France)
Inventeur(s)
Forge, Vincent
Mathevon, Carole
Cayla, Aurélie
Rault, François
Abrégé
The present invention relates to a composite material comprising at least one textile commodity polymer and protein fibers comprising at least one amyloid structure. The invention also relates to a method for preparing such a material, as well as to the use of such a material for adsorbing a pollutant or extracting metal ions.
C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
D01F 2/00 - Filaments, ou similaires, artificiels, à un seul composant, formés de cellulose ou de dérivés de la celluloseLeur fabrication
D01F 4/04 - Filaments, ou similaires, artificiels, à un seul composant, formés de protéinesLeur fabrication à partir de la caséine
D01F 6/46 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de mélanges de polymères obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone comme constituant majeur avec d'autres polymères ou des composés de bas poids moléculaire de polyoléfines
D01F 6/88 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de mélanges de produits de polycondensation comme constituant majeur avec d'autres polymères ou des composés de bas poids moléculaire
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
D01F 6/44 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de mélanges de polymères obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone comme constituant majeur avec d'autres polymères ou des composés de bas poids moléculaire
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
Inventeur(s)
Delon, Antoine
Grichine, Alexeï
Wang, Irène
Grojean, Marc
Abrégé
The invention relates to a device (1, 1A, 1B, 1C, 1D) for creating an evanescent field (3) at the surface of a dioptre (4) separating two media that have different refractive indices, the device comprising: - a light source (6A, 6B, 6C, 6D); - a lens (9A, 9B, 9C, 9D) comprising an object focal plane positioned at the surface of the dioptre, and a pupil plane (PP) comprising a subcritical region (R2) and a supercritical region (R1); - an active optical means (7A, 7B, 70, 7D) comprising an active surface (10A, 10B, 10C, 10D) extending at least through the entirety of the supercritical region (R1') of a conjugate plane of the pupil plane or extending through a conjugate plane of the object focal plane of the lens, the active optical means comprising a set of individually controllable microelements configured to illuminate the entire supercritical region of the lens.
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
G02B 27/56 - Optique utilisant des ondes évanescentes, c.-à-d. ondes non homogènes
G02B 26/08 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander la direction de la lumière
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE SAVOIE MONT BLANC (France)
Inventeur(s)
Chatenet, Marian
Doan, Huong
Sgarbi, Ricardo
Abrégé
A method for a synthesis of a metal catalyst, including providing at least one metal complex including a metal ion and a non-chelating complexing agent having carbon, the complex having a decomposition temperature, and performing a pyrolysis of the complex at a temperature greater than or equal to a decomposition temperature of the complex, whereby inducing a formation of nanoparticles surrounded by a carbon matrix to form the catalyst. Thanks to the carbon matrix, the catalysts provided herein can be corrosion resistant, self-healing, more cost-effective, and can have higher catalytic activity. The synthesis of the catalyst and its properties can furthermore be improved compared to catalysts formed from a complex including a chelating.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (France)
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
Inventeur(s)
Laurendeau, Matthieu
Jolivet, Frédéric
Gorges, Sébastien
Bernard, Guillaume
Rit, Simon
Desbat, Laurent
Abrégé
The invention relates to a method for reconstructing an object by x-ray tomography by means of x-ray sources and detectors. The method comprises the following steps: obtaining (EO) positions of the x-ray sources and detectors; pre-calculating (E1) a set of directions; calculating (E2) a tomographic incompleteness vector map; calculating (E3) a tomographic incompleteness map of the metrics IM(x); calculating (E4) regularization terms from the tomographic incompleteness vector map and from the tomographic incompleteness map of the metrics; and solving (E5), iteratively, a regularized tomographic reconstruction problem by means of the calculated regularization terms.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Fribourg, Guillaume
Battail, Sylvain
Favre, Matthieu
Francoise, Hugo
Grandvallet, Christelle
Villeneuve, François
Doutre, Pierre-Thomas
Vignat, Frédéric
Marin, Philippe
Abrégé
The invention relates to a connecting device (30) suitable for connecting at least one first element (17) and one second element to one another, and for moving the or each first element relative to the second element. The connecting device comprises a fixed portion (31), a movable portion (32) which is kinematically linked and connected to the or each first element, and a joint (33) which connects the fixed portion and the movable portion at least pivotably about an axis of rotation (A30). The joint comprises, for the axis of rotation, at least one strand (37) that is elastically deformable and extends in a manner that is both substantially parallel and offset relative to the axis of rotation, and that connects at least one fixed support (318) of the fixed portion to at least one movable support (36) of the movable portion.
H01H 1/22 - Contacts caractérisés par la manière dont les contacts coopérants s'engagent en butant l'un contre l'autre avec membre pivotant rigide portant le contact mobile
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITÉ GRENOBLE ALPES (France)
Inventeur(s)
Holzinger, Michaël
Mohanty, Anurag
Gross, Andrew
Abrégé
An electrode comprising a self-supporting porous structure of expanded graphite and an electrical connector. Method for manufacturing a self-supporting porous structure of expanded graphite, said method comprising the following steps: preparing a suspension of expanded graphite particles in a liquid; sonicating said suspension of graphite particles by applying ultrasound, to obtain a homogenized suspension; and filtering said homogenized suspension under pressure to obtain an expanded porous structure which is at least partially and preferably substantially dry.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
Inventeur(s)
Mondet, Julie
Mossuz, Pascal
Lac, Baptiste
Abrégé
A prognostic risk score for chemosensitive cancer, in particular acute myeloid leukemia (AML), based on somatic genetic abnormalities affecting certain genes of the mitochondrial genome.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
9.
METHOD FOR DETERMINING SPATIAL COORDINATES OF A SOURCE CAUSING A DISPERSION EFFECT
COMMISSARIAT A L’ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITE GRENOBLE ALPES (France)
Centre National de la Recherche Scientifique (France)
Institut Polytechnique de Grenoble (France)
Inventeur(s)
Lopez-Ferber, Roman
Leirens, Sylvain
Georges, Didier
Abrégé
A method for determining spatial coordinates of a source causing a dispersion effect in a domain, the dispersion effect being approximated by a system of partial differential equations, the method including computer-implemented steps, of obtaining measurements each quantifying at a point in space in the domain and at a given time a state variable modeled by the system of partial differential equations at the point and at the time, and of iteratively minimizing differences between the measurements and the computations of the system of equations to locate a position of the source. The system of equations is expressed in terms of finite differences generated by radial basis functions, the system of equations being solved in a least-squares context, using a least-squares solver, the system of equations having been subject to adjoint quadratic solution with radial basis functions chosen from polyharmonic-spline functions, inverse-multiquadric functions, or Gaussian functions.
COMMISSARIAT A L’ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Darmau, Bastien
Gross, Andrew
Texier-Nogues, Isabelle
Abrégé
A device for transdermal electrochemical measurements, comprising a polymeric support having a surface provided for contact with skin, an array of polymeric microneedles integral with the support and projecting outward from the surface of the support, and a porous and/or nano/micro-structured bioelectrode. A biologically active species is immobilized on the surface of a conductive material. The microneedles and a surface of contact of the support with the skin are formed of a biocompatible crosslinked hydrogel, non-electron-conductive in the dry state and electrolyte-conductive upon contact with an aqueous fluid. The bioelectrode is arranged in contact with the hydrogel and is free of direct contact with the skin. Methods for preparing and using the device are also described.
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques invasifs, p. ex. introduits dans le corps par un cathéter
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
COMMISSARIAT A L’ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Gross, Andrew
Darmau, Bastien
Texier-Nogues, Isabelle
Abrégé
A device having a polymeric support with a surface for contact with skin, an array of solid polymeric microneedles integral with the support and projecting outward from the surface of the support provided for contact with the skin, and an electrode. The microneedles and the surface of contact of the support with the skin are formed of a crosslinked hydrogel, non-electron-conductive in the dry state and electrolyte-conductive upon contact with an aqueous fluid. The electrode is arranged in contact with the hydrogel provided to swell upon contact with an aqueous fluid and is free of direct contact with the skin. A method for preparing the device and uses thereof are also described.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques invasifs, p. ex. introduits dans le corps par un cathéter
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (France)
Inventeur(s)
Chebloune, Yahia
El Kennani, Sara
Abrégé
An in vitro or ex vivo method for producing and isolating a cell subpopulation including T cells specific for an antigen linked to a disease of interest, which includes steps of obtaining, from an isolated human biological sample, a population of mononuclear cells including T cells specific for the antigen with a high proliferative capacity, culturing these mononuclear cells in a suitable cell culture medium containing the antigen, and isolating T cells specific to the antigen which do not express the CD45RO and CD27 markers at their surface. The cell subpopulation thus obtained and isolated finds application in particular for the treatment of the disease of interest.
A61K 35/17 - LymphocytesLymphocytes BLymphocytes TCellules tueuses naturellesLymphocytes activés par un interféron ou une cytokine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
B01D 15/38 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction spécifique non couverte par un ou plusieurs des groupes , p. ex. chromatographie d'affinité, chromatographie d'échange par ligand ou chromatographie chirale
C12N 5/0783 - Cellules TCellules NKProgéniteurs de cellules T ou NK
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Lanoë, Pierre-Henri
Loiseau, Frédérique
Abrégé
The present invention relates to compounds of formula (I). It also relates to a process for preparing a compound as well as to the use of these compounds as a medicament, in particular in the treatment of cancer.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Gaudin, Gilles
Miron, Ioan Mihai
Yang, Haozhe
Vatajelu, Ioana
Pinna, Daniele
Abrégé
A classification device, including a pre-processing stage, a material system and an identification stage. The pre-processing stage transforms a signal of interest into an excitation signal; the material system includes a magnetic medium subdivided into a plurality of zones either in a first magnetic state or in a second magnetic state, an excitation module generating, from the excitation signal, a physical excitation quantity adapted to displace the magnetic domain walls in the magnetic medium, and a reading module measuring the final magnetic configuration reached by the magnetic medium; and the identification stage determines a class to which the signal of interest belongs from the final magnetic configuration.
G16C 60/00 - Science informatique des matériaux, c.-à-d. TIC spécialement adaptées à la recherche des propriétés physiques ou chimiques de matériaux ou de phénomènes associés à leur conception, synthèse, traitement, caractérisation ou utilisation
G16C 20/70 - Apprentissage automatique, exploration de données ou chimiométrie
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITÉ GRENOBLE ALPES (France)
Inventeur(s)
Cosnier, Serge
Nedellec, Yannig
Berezovska, Anastasiia
Maciel Buzzetti, Paulo Henrique
Abrégé
An electrode comprising an electronically conductive material at least in part forming a reservoir, the material being permeable and porous; an enzyme compound disposed in the reservoir; and optionally a current collector.
C07D 519/00 - Composés hétérocycliques contenant plusieurs systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un système carbocyclique commun non prévus dans les groupes ou
C07D 207/46 - Composés hétérocycliques contenant des cycles à cinq chaînons, non condensés avec d'autres cycles, ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle avec les hétéro-atomes liés directement à l'atome d'azote du cycle
G01N 24/12 - Recherche ou analyse des matériaux par l'utilisation de la résonance magnétique nucléaire, de la résonance paramagnétique électronique ou d'autres effets de spin en utilisant la résonance double
17.
METHOD OF SYNTHESIS OF COLLOIDAL InSb QUANTUM DOTS
COMMISSARIAT À L'ENERGIE ATOMATIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Reiss, Peter
Kwon, Yongju
Abrégé
The present invention relates to a method of synthesis of colloidal InSb quantum dots (InSb QDs) comprising a premixing step of In and Sb precursors at a temperature of less than 100°C, under stirring.
C09K 11/74 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant de l'arsenic, de l'antimoine ou du bismuth
18.
DEVICE FOR RECOVERING ELECTRICAL ENERGY BY CONVERTING MECHANICAL ENERGY
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Boccalero, Gregorio
Yonnet, Jean-Paul
Sylvestre, Alain
Abrégé
The proposed recovery device comprises a stator (11), a slide (12), return means (13), a supporting platform (14), a chassis (15) and an electrical pulse integration circuit (16). It constitutes a magnetically bistable device which, by construction, is able to ensure that the amount of energy collected by integration of each electric pulse it generates is controlled and substantially constant. It has higher performance than previous solutions, is easily adaptable in dimensions, and has a manufacturing and maintenance cost that is low enough that it can be produced on an industrial scale and deployed widely.
H02K 35/02 - Génératrices avec système de bobines, aimant, induit, ou autre partie du circuit magnétique à mouvement alternatif, oscillant ou vibrant avec des aimants mobiles et des systèmes de bobines fixes
H02K 1/34 - Parties du circuit magnétique à mouvement alternatif, oscillant ou vibrant
H02K 35/04 - Génératrices avec système de bobines, aimant, induit, ou autre partie du circuit magnétique à mouvement alternatif, oscillant ou vibrant avec des systèmes de bobines mobiles et des aimants fixes
H02K 7/18 - Association structurelle de génératrices électriques à des moteurs mécaniques d'entraînement, p. ex. à des turbines
19.
REGULATION SYSTEM FOR A MULTI-ACTIVE BRIDGE CONVERTER WITH HYBRID SUPPLY, ASSOCIATED METHOD AND DEVICE
Commissariat à l'énergie atomique et aux énergies alternatives (France)
UNIVERSITE GRENOBLE ALPES (France)
Centre national de la recherche scientifique (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Tarraf, Rebecca
Frey, David
Leirens, Sylvain
Carcouet, Sébastien
Maynard, Xavier
Abrégé
The present invention [relates to] a regulation system (28) for a multi-active bridge converter (10) with hybrid supply, comprising:
an input current port (20) comprising an H-shape switch bridge (30) having a switch (T1) controlled by a first law having a first duty cycle,
at least one output voltage port (22, 24) comprising an H-shape switch bridge (38, 40), one switch (T 21, T 31) of which is controlled by a second law which is phase-shifted with respect to the first law,
the regulation system (28) regulates the converter (10) to a setpoint comprising a setpoint current value for the current of the current port (20) and a setpoint voltage value for a voltage port (22, 24).
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
20.
DEVICE AND SYSTEM FOR TOMOGRAPHY OF THE LUNGS AND ASSOCIATED TOMOGRAPHY METHOD
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Ioana, Cornel
Digulescu Popescu, Angela
Abrégé
The invention relates to a device (1) and a system for tomography of the lungs (20), the device comprising a support member (10), and at least five transceivers (11) attached to the support member (10) configured to transmit and receive an ultrasonic wave of variable frequency over a frequency range, the transceivers (11) being arranged in at least two first assemblies (110) each facing a lung (20) of a human or animal body (2). The associated tomography method comprises transmitting and receiving the ultrasound wave according to transmission and reception profiles, by the transceivers (11), and analysing the deformation between these profiles in order to obtain the speed of the wave as a function of the frequency and direction of propagation of the wave, and constructing a tomogram on the basis of an item of data relating to this speed.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Laborie, Leo
Hida, Rachid
Jalaguier, Eric
Lefevre, Gauthier
Navarro, Gabriele
Veyret, Killian
Zucchi, Xavier
Bon, Romain
Abrégé
A resistive memory cell includes a lower electrode based on one of the following materials: titanium nitride TiN, tantalum nitride TaN, tantalum Ta, copper Cu, tungsten W, platinum Pt, gold Au or silver Ag, an upper electrode, an active layer having a first contact surface with the lower electrode and a second contact surface with the upper electrode, the active layer including a zone, referred to as the local zone, the local zone being made of a material including vanadium, oxygen and Ti or Ta or Cu or W or Pt or Au or Ag, the local zone extending from the first contact surface, the rest of the active layer being made of conductive vanadium oxide.
H10N 70/00 - Dispositifs à l’état solide n’ayant pas de barrières de potentiel, spécialement adaptés au redressement, à l'amplification, à la production d'oscillations ou à la commutation
H10B 63/00 - Dispositifs de mémoire par changement de résistance, p. ex. dispositifs RAM résistifs [ReRAM]
22.
OPTOELECTRONIC DEVICE FOR ON-DEMAND DEFORMATION OF A CRYSTALLINE SEMICONDUCTOR PORTION OPTICALLY COUPLED TO A WAVEGUIDE
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Pauc, Nicolas
Chretien, Jérémie
Abrégé
The invention relates to an optoelectronic device (1) for on-demand deformation of a crystalline semiconductor portion (10), comprising: o a deformation structure (20), comprising: a structured thin film (23) having two arms (23.1) suspended above a cavity; o the crystalline semiconductor portion (10), resting on the two arms (23.1); o a waveguide (2) optically coupled to the crystalline semiconductor portion (10); o an electrical deformation device, suitable for deforming the crystalline semiconductor portion (10) and comprising: an electrical power source suitable for generating an electrical control signal; and an electrical circuit (31, 32, 33, 34; 35, 36) suitable for generating, in response to the electrical control signal, an electric field or a temperature field in the arms (23.1) which induces a deformation of the arms (23.1) and therefore of the crystalline semiconductor portion (10).
H01L 33/02 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs
H01L 33/10 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure réfléchissante, p.ex. réflecteur de Bragg en semi-conducteur
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
Inventeur(s)
Jacquier-Sarlin, Muriel-Réjane
Buisson, Alain
Abrégé
The invention relates to a method for the early in vitro diagnosis of a neurodegenerative disease in a human or an animal subject, the method comprising the step of detecting the presence of at least one marker chosen from among forms derived from amyloid beta peptides (Aβ) chosen from among the oligomers of these peptides and the prefibrillar and fibrillar aggregate forms of these peptides, and forms derived from phosphorylated tau proteins chosen from among the hyperphosphorylated forms of these proteins, the aggregate forms of these proteins and the modified phosphorylated tau proteins resulting from one or more post-translational modifications, the presence of the one or more markers being detected in a stool sample from this subject.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
24.
METHOD FOR DETERMINING A DEFORMATION OF AN AREA OF A PART OBTAINED BY ADDITIVE MANUFACTURING
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Ricart, Thibault
Basrour, Skandar
Museau, Matthieu
Robert, Pascal
Béraud, Nicolas
Paris, Henri
Abrégé
The method is for the discriminant monitoring of a composite multi-material assembly (1) having at least one internal layer (10) made of a first, electrically conductive composite material and a second layer (11) made of a second, electrically insulating composite material, the second layer (11) covering the first internal layer (10). The method includes: —preparing the composite multi-material assembly (1) by exposing a portion (101) of the internal layer (10), which constitutes a first electrode; —applying a second electrode (103) to the surface of the second layer (11), one of these electrodes (103) being earthed; —performing discriminant monitoring wherein a current is generated between the first electrode (101) and the second electrode (103) by applying a threshold voltage Us predetermined by calibration to characterize a lack of structural defects, the appearance of a breakdown at a voltage lower than the threshold voltage Us being indicative of the presence of at least one structural defect in the composite assembly (1).
G01B 7/24 - Dispositions pour la mesure caractérisées par l'utilisation de techniques électriques ou magnétiques pour mesurer les déformations dans un solide, p. ex. au moyen d'une jauge de contrainte à résistance en utilisant la variation des propriétés magnétiques
B33Y 40/00 - Opérations ou équipements auxiliaires, p. ex. pour la manipulation de matériau
25.
IMPROVED CLASSIFICATION DEVICE OF THE "IN MATERIO COMPUTING" TYPE
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Gaudin, Gilles
Miron, Ioan Mihai
Yang, Haozhe
Vatajelu, Ioana
Abrégé
This classification device (1) has a pre-processing stage (10), an identification stage (30), and a material system (20) interposed between the pre-processing stage and the identification stage. The material system (20) comprises an inhomogeneous magnetic medium (50), which is subdivided into a plurality of zones (51), each zone being in magnetic communication with at least one neighbouring zone through a coupling link (53). According to the invention, the material system (20) further comprises a control means (71, 73) for setting the coupling value of each coupling link.
Commissariat à l'énergie atomique et aux énergies alternatives (France)
THALES (France)
Centre national de la recherche scientifique (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Grezes, Cécile
Vila, Laurent
Attane, Jean-Philippe
Bibes, Manuel
Abrégé
An electronic system includes an electronic device having a stack of layers, the stack including a first electrode, a subassembly with electrically controllable remanent states, a two-dimensional electron gas, a magnetic subassembly comprising at least one magnetic layer, and a second electrode having two first contacts and a second contact. The system also includes a writing device writing remanent states by applying an electric field between the two electrodes, and a Hall-effect reading device reading the remanent state by applying a current between the two first contacts and by measuring the voltage between the second contact and a reference potential.
G11C 11/16 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments magnétiques utilisant des éléments dans lesquels l'effet d'emmagasinage est basé sur l'effet de spin
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
ECOLE CENTRALE DE LYON (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Tedjini, Smail
Allane, Dahmane
Duroc, Yvan
Abrégé
A novel RFID communication device is proposed which allows the detection and electronic processing not only of the response signal backscattered at the fundamental frequency f0 of the reader, but also at least one response signal backscattered at a harmonic frequency, before feeding them to the conventional receive chain of an RFID reader. The joint use of the signal at the fundamental frequency of the reader and at least one signal at a harmonic frequency allows the reader's performance to be improved. The RFID reader can additionally be provided with novel functionalities by virtue of suitable software processing. It is applicable to the field of communications between a reader and passive transponders in UHF RFID and to the field of the Internet of Things.
G06K 7/10 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire
28.
QUANTATIVE ANALYSIS OF FLUCTUATIONS IN BIOLOGICAL TISSUES VIA MULTISPECTRAL PHOTOACOUSTIC IMAGING
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Arnal, Bastien
Bossy, Emmanuel
Godefroy, Guillaume
Abrégé
A method is disclosed for processing photoacoustic images, this method including: obtaining a time series of images of a sample, the images being acquired by a photoacoustic imaging system at Mx excitation-pulse wavelengths, with N images acquired per wavelength; performing multispectral spatio-temporal filtering via singular value decomposition applied to all of the N*Mx acquired images so as to obtain N*Mx filtered images; for each wavelength, computing a filtered variance image based on the N filtered images, a pixel of coordinate r in the filtered variance image being equal to the variance of the distribution of the values of pixels of same coordinate r in the filtered images obtained for this wavelength; and correcting the filtered variance image by subtracting a variance of the residual electronic noise after the multispectral spatio-temporal filtering has been performed, the noise being produced by the sensors of ultrasonic waves of the photoacoustic imaging system.
Commissariat à l'énergie atomique et aux énergies alternatives (France)
THALES (France)
Centre national de la recherche scientifique (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Attane, Jean-Philippe
Vila, Laurent
Bibes, Manuel
Abrégé
The present invention relates to an electronic device comprising:
a first electrode comprising a contact,
a ferroelectric subassembly having a ferroelectric polarization,
a spin polarization subassembly which spin-polarizes an incident current and comprises a layer of ferromagnetic or ferrimagnetic material,
an interfacing subassembly which is arranged between the two subassemblies and converts the spin current into a charge current, the ferroelectric subassembly and the interfacing subassembly having a contact, and
a second electrode which comprises two contacts and delimits the polarization subassembly,
the contact of the first electrode changing the state of polarization by applying a potential difference between this contact and another contact.
H10N 50/20 - Dispositifs à courant commandé à polarisation de spin
G11C 11/16 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments magnétiques utilisant des éléments dans lesquels l'effet d'emmagasinage est basé sur l'effet de spin
H01L 29/66 - Types de dispositifs semi-conducteurs
COMMISSARIAT A L’ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITE GRENOBLE ALPES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Centre national de la recherche scientifique (France)
Inventeur(s)
Martinez, Christophe
Rainouard, Fabian
Oudet, Edouard
Abrégé
A method for manufacturing an image projection device for projecting an image onto an eye, includes an emission surface S. The surface S comprises a set of waveguides, a set of diffraction gratings and a set of electrodes. Each grating is positioned at the intersection of one of the guides and one of the electrodes so as to form an emission point for a light wave, the set of waveguides being arranged in a waveguide configuration, and the set of electrodes being arranged in an electrode configuration. The method comprises a phase of designing the device and a phase of physically manufacturing the device thus designed. The design phase comprises the step consisting in determining the waveguide configuration or the electrode configuration, the determined configuration being a non-rectilinear isoline configuration defined in the plane defined by the emission surface S and generating an aperiodic distribution of the emission points.
CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Zebda, Abdelkader
Cinquin, Philippe
Ben Tahar, Awatef
Tubbs, Emilie
Benhamou, Pierre-Yves
Lablanche, Sandrine
Abrégé
A pancreatic cell receiving matrix including a semi-permeable wall and a porous body including a first set of cavities including pancreatic cells, and a second set of cavities free of pancreatic cells. The first set of cavities and the second set of cavities are not fluidically connected to one another. The cavity or cavities left free of cells create paths for the nutrients and gases to diffuse in the matrix, and they form a nutrient and gas reserve area in the matrix. The matrix limits and preferably prevents nutrient and gas depletion of the pancreatic cells. Their mortality is therefore reduced, allowing better insulin delivery.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITE GRENOBLE ALPES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Marcoux, Pierre
Roupioz, Yoann
Zelsmann, Marc
Picard, Emmanuel
O’connell, Larry
Abrégé
A method for detecting a lytic activity of one or more types of phages or of the activity of one or more antibiotics with respect to a bacterial strain, the method including using a first multiwell plate, each well receiving a sample containing phages or antibiotics, making at least one deposit on a transparent area of a support, the deposit containing bacteria of the bacterial strain, applying the first plate against the support so that each sample in each well comes into contact with the deposit, for each well, determining, using the detection means, the activity or absence of activity of the phage or antibiotic with respect to the bacterial strain, taking into account the intensity of light signals transmitted through each well and/or the variation thereof over time.
C12Q 1/18 - Test de l'activité antimicrobienne d'un matériau
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 1/32 - Inoculateur ou échantillonneur du type à champs multiples ou en continu
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
UNIVERSITE SAVOIE MONT BLANC (France)
Inventeur(s)
Alleysson, David
Abrégé
A method for converting an initial datum between a colour space of a first colorimetric system and a colour space of a second colorimetric system, the initial datum being formed of at least one element expressed in a colorimetric reference system, the method includes: converting the initial datum into a projected datum, by expressing the at least one element in the colour space of the first colorimetric system; adapting the projected datum into an adapted datum, by expressing the at least one element in the colour space of the second colorimetric system. The colour space of the first colorimetric system and of the second colorimetric system are each a hyperbolic space defined by a hyperbolic metric projective reference system.
G09G 5/02 - Dispositions ou circuits de commande de l'affichage communs à l'affichage utilisant des tubes à rayons cathodiques et à l'affichage utilisant d'autres moyens de visualisation caractérisés par la manière dont la couleur est visualisée
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
SAFT (France)
UNIVERSITE GRENOBLE ALPES (France)
UNIVERSITE SAVOIE MONT BLANC (France)
Inventeur(s)
Roy, Francis
Mermaz Rollet, Guillaume
Peuchant, Thomas
Khatokar Amarnath, Rakesh
Lahlou, Anas
Herpe, David
Thivel, Pierre Xavier
Leprêtre, Jean Claude
Bultel, Yann
Abrégé
The present invention relates to a method for carrying out pulsed charging of an energy storage element (4) comprising, in a first phase of a charging cycle (E1), commanding a voltage profile (VC) having voltage regulation-driven increments (S1, S2, S3, S4, S5) defining a current profile (IC) in a charging cycle of a predetermined duration, and wherein a voltage increment (S1, S2, S3, S4, S5) is computed at a voltage amplitude at the time of a calculation step i according to a function depending on an estimate of the no-load voltage and on an estimate of the internal resistance at said time, on a coefficient n defining the charging duration and on the nominal capacity of the storage element. The invention is applicable to the fast-charging protocol, in particular for electromobility applications.
Centre National de la Recherche Scientifique (France)
Commissariat à l'Energie Atomique et aux Energies Alternatives (France)
Centre Hospitalier Universitaire de Grenoble Alpes (France)
Institut National de la Santé et de la Recherche Médicale (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Macek Jilkova, Zuzana
Govin, Jérôme
Emadali, Anouk
Petosa, Carlo
Wong, Yung-Sing
Abrégé
The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds.
The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds.
The present invention relates to the applications thereof, in particular in therapeutic treatment.
The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds.
The present invention relates to the applications thereof, in particular in therapeutic treatment.
The present invention relates in particular to compound having the following structure:
The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds.
The present invention relates to the applications thereof, in particular in therapeutic treatment.
The present invention relates in particular to compound having the following structure:
The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds.
The present invention relates to the applications thereof, in particular in therapeutic treatment.
The present invention relates in particular to compound having the following structure:
wherein R, R′, RA, Nu, R1, R2, R3, and R4 are each independently an atom or a chemical group of atoms.
C07D 401/12 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
A61K 31/4706 - 4-Aminoquinoléines8-Aminoquinoléines, p. ex. chloroquine, primaquine
A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
C07D 215/48 - Atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène
C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
C07F 7/18 - Composés comportant une ou plusieurs liaisons C—Si ainsi qu'une ou plusieurs liaisons C—O—Si
C07F 11/00 - Composés contenant des éléments des groupes 6 ou 16 du tableau périodique
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
UNIVERSITÉ GRENOBLE ALPES (France)
Inventeur(s)
Coutrix, Céline
Conil, Aurélien
Abrégé
The present invention relates to a tangible control device (10) for controlling a variable datum, comprising an interface (11) capable of rotating about a central axis for a first variable datum control, this interface comprising a frame (12) and a slider (13) supported by the frame (12), the slider being movable along the frame (12) for a second variable datum control. The frame (12) comprises a series of segments (20a, 20b, 20c, 20d), each segment being hinged with the segment adjacent thereto by means of a hinge pin to permit an angular movement of one segment with respect to the other. The tangible control device (10) comprises an electromechanical actuator (40) for driving the variable geometry that comprises an electric motor and a cascade of gears.
G06F 3/0354 - Dispositifs de pointage déplacés ou positionnés par l'utilisateurLeurs accessoires avec détection des mouvements relatifs en deux dimensions [2D] entre le dispositif de pointage ou une partie agissante dudit dispositif, et un plan ou une surface, p. ex. souris 2D, boules traçantes, crayons ou palets
G06F 3/0362 - Dispositifs de pointage déplacés ou positionnés par l'utilisateurLeurs accessoires avec détection des translations ou des rotations unidimensionnelles [1D] d’une partie agissante du dispositif de pointage, p. ex. molettes de défilement, curseurs, boutons, rouleaux ou bandes
37.
IMAGING METHOD, ENDOSCOPE AND COMPUTER PROGRAM PRODUCT
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Bossy, Emmanuel
Caravaca Aguirre, Antonio Miguel
Abrégé
The method for imaging an object to be imaged includes: generating, using a lighting device (2), a series of illumination patterns; for each illumination pattern, carrying out a stimulating phase in which translations of the illumination pattern are carried out over an entrance of a square-core multimode optical fiber (4) by means of at least one translating device (3a) of an optical system (3) placed between the lighting device (2) and the entrance of the square-core multimode optical fiber (4), the translations being carried out in a plane parallel to the entrance plane of the square-core multimode optical fiber (4); for each stimulating phase, carrying out an acquiring phase in which the signal generated by the illumination pattern on the object to be imaged (O) placed at the exit of the square-core multimode optical fiber (4) is measured by a signal-measuring device (5; 9); and reconstructing, using a computing device (6), by the signal measured in each acquiring phase, the object to be imaged.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
A61B 1/04 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision
A61B 1/07 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement utilisant des moyens conduisant la lumière, p. ex. des fibres optiques
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
Centre National de la Recherche Scientifique (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Kalita, Dipankar
Bouchiat, Vincent
Marty, Laetitia
Bendiab, Nedjma
Abrégé
A sensor device including a conductive graphene film covered on at least one side by a graphene support layer of parylene, a detection element configured to sense an environmental change, and an electrode. The parylene repairs some defects of the conductive graphene film without damaging, polluting, or degrading the conductivity of conductive graphene film.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Utrilla Bustamante, Maria De La Candelaria
Buire, Jérôme
Debusschere, Vincent
Hadjsaid, Nouredine
Abrégé
The invention relates to a method for the primary control of an inverter interfacing an intermittent energy source and an AC power grid. Through each of its various aspects, the invention proposes a novel droop command and control loop or droop control loop (5) that adapts to the variations in active power available at the inverter (1). This loop may advantageously be implemented on each inverter that, among a plurality of generators connected to the grid, interfaces an intermittent energy source (2), while at the same time guaranteeing: a. correct allocation of active power among the generators, and b. correct signalling, via the frequency at the point of connection of each generator to the grid, of the fact that each generator has reached its active power limits, thereby allowing protective measures to be activated so that each generator of the plurality returns to its active power range.
H02J 3/38 - Dispositions pour l’alimentation en parallèle d’un seul réseau, par plusieurs générateurs, convertisseurs ou transformateurs
H02J 3/48 - Dispositions pour l’alimentation en parallèle d’un seul réseau, par plusieurs générateurs, convertisseurs ou transformateurs contrôlant la répartition de puissance entre les générateurs, convertisseurs ou transformateurs contrôlant la répartition de la composante en phase
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
CENTRE HOSPITALIER REGIONAL DE GRENOBLE (France)
COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
Inventeur(s)
Busser, Benoît
Deniaud, Aurélien
Lelievre, Pierre
Sancey Galliot, Lucie
Renier, Nathan
Valkenier-Van Dijk, Elisabeth H.
Jabin, Ivan
Abrégé
1234232213131218188-alkyl group being optionally substituted, n being an integer comprised between 1 and 4 (preferably equal to 1), They exhibit high cytotoxicity against cancer cells.
C07D 233/64 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, non condensés avec d'autres cycles comportant deux liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des radicaux hydrocarbonés substitués, liés aux atomes de carbone du cycle, p. ex. histidine
C07D 235/12 - Radicaux substitués par des atomes d'oxygène
C07D 263/32 - Composés hétérocycliques contenant des cycles oxazole-1, 3 ou oxazole-1, 3 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
C07D 277/24 - Radicaux substitués par des atomes d'oxygène
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Picard, Cyril
Charlaix, Elisabeth
Chèvremont, William
Abrégé
The method p1 for converting osmotic energy into hydraulic energy and the method p2 for desalination, include pressurisation/depressurisation and isochoric washing of an aqueous solution containing a salt in the presence of a selective hydrophobic nanoporous material of which the nanoporous volume within the material is only accessible to fresh water and which has a nanoporosity volume fraction ranging from 0.2 to 1 so as to convert osmotic energy into hydraulic energy or conversely to desalinate water, preferably sea water or brine.
B01D 61/00 - Procédés de séparation utilisant des membranes semi-perméables, p. ex. dialyse, osmose ou ultrafiltrationAppareils, accessoires ou opérations auxiliaires, spécialement adaptés à cet effet
B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétésProcédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
C02F 1/44 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par dialyse, osmose ou osmose inverse
C02F 103/08 - Eau de mer, p. ex. pour le dessalement
F03G 7/00 - Mécanismes produisant une puissance mécanique, non prévus ailleurs ou utilisant une source d'énergie non prévue ailleurs
42.
OPTOELECTRONIC DEVICE, SINGLE-PHOTON GENERATOR, MEMORY, MULTIPLEXER, IMPLANT AND ASSOCIATED METHODS
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
UNIVERSITE GRENOBLE ALPES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
UNIVERSITE PAUL SABATIER TOULOUSE III (France)
INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Pernot, Julien
Masante, Cedric
Rouger, Nicolas
Kah, Martin
Hebert, Clement
Abrégé
A device including a first portion, a second portion, a first contact and a second contact, the first portion being made of a semiconductor having a first doping, the second portion being made of a semiconductor having a second doping different than the first, the first portion and the second portion forming a p/n junction including a depletion zone in the first portion, the contacts being configured so that when an electric voltage (V1) is applied between the contacts, a dimension of the depletion zone depends on a value of the electric voltage, an ionization energy being defined for dopants of the second portion. The device includes an emitter generating a radiation having an energy greater than the ionization energy and illuminating the second portion with the radiation.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Salem, Bassem
Vauche, Laura
Legallais, Maxime
Baron, Thierry
Gwoziecki, Romain
Plissonnier, Marc
Abrégé
A method for preparing a microelectronic component includes cleaning of the surface of an exposed layer with a basis of a III-V material by a cyclic plasma treatment, each cycle comprising a purge phase and a plasma treatment phase. During the formation of the plasma, a bias voltage is applied to the substrate. The method further includes depositing, on the cleaned surface, a subsequent layer. The method provides an optimal cleaning of the exposed layer while minimising, and preferably avoiding degradation of the structure. The preparation method thus makes it possible to improve the quality of the interface between the layer with a basis of a III-V material and the subsequent layer. The electrical properties of the component are consequently improved.
Commissariat à l'Energie Atomique et aux Energies Alternatives (France)
Institut Polytechnique de Grenoble (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Institut National de Recherche en Informatique et en Automatique (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Da Silva, Mike
Thevenon, Pierre-Henri
Puys, Maxime
Mocanu, Stéphane
Abrégé
The present description concerns a method of identification of risks of cyberattacks on a programmable logic controller, the method comprising: the generation of a digital representation of a minimized finite-state transducer based on a specification of a controller logic of the programmable logic controller, the minimized finite-state transducer comprising a set of source states, a set of destination states, and a set of transitions from a source state to a destination state based on an input data value; the generation of a second computer file, based on a first computer file identifying a subset of sensitive states, the second file comprising a list of critical transitions associated with the sensitive states, and for each transition, a list of the input data; and the generation of a fourth computer file indicating input data to be protected which are both associated with critical transitions and with a corruption risk.
G06F 21/57 - Certification ou préservation de plates-formes informatiques fiables, p. ex. démarrages ou arrêts sécurisés, suivis de version, contrôles de logiciel système, mises à jour sécurisées ou évaluation de vulnérabilité
45.
NOVEL CANNABINOID-INSPIRED INHIBITORS OF AUTOTAXIN
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
Inventeur(s)
Eymery, Mathias
Mccarthy, Andrew
Boumendjel, Ahcène
Abrégé
The present invention relates to the novel compounds of general formula (I) as defined below. The invention further relates to a pharmaceutical composition comprising said compound of formula (I). The invention further relates to said compound of general formula (I) as defined below for use as medicament in the treatment of an autotaxin (ATX) related disease.
C07D 405/10 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITÉ GRENOBLE ALPES (France)
UNIVERSITÉ SAVOIE MONT BLANC (France)
UNIVERSITÉ CLERMONT AUVERGNE (France)
Inventeur(s)
Point, Sébastien
Beroud, Maïlys
Khazaz, Sarah
Mondillon, Laurie
Mermillod, Martial
Abrégé
Security lighting device (1) comprising a front face (3) for displaying a pictogram, a rear face and at least one thick wall (5) extending between the front face and the rear face, said security lighting device comprising first light means designed to illuminate the front face (3), said lighting device (1) being characterized in that it further comprises second light means installed on said at least one thick wall (5), said second light means being chosen such that the emitted light has a combination of colour and/or form adapted to influence the decision of the user on the chosen direction of evacuation according to their position in the environment.
G09F 19/18 - Moyens de publicité ou de présentation non prévus ailleurs utilisant des effets optiques particuliers comportant l'utilisation de moyens de projection optique, p. ex. projection d'images sur les nuages
G09F 13/04 - Enseignes, tableaux ou panneaux éclairés de derrière l'illustration
G09F 9/37 - Dispositifs d'affichage d'information variable, dans lesquels l'information est formée sur un support, par sélection ou combinaison d'éléments individuels dans lesquels le ou les caractères désirés sont formés par une combinaison d'éléments individuels à éléments mobiles
COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (France)
UNIVERSITE GRENOBLE ALPES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Danouchi, Kamal
Abrégé
The present invention relates to a reading circuit (10) having differential amplification comprising: • a. a resistive component (12) having discrete states corresponding to different resistance values of the resistive component (12); • b. a reading block (14) for reading the state of the resistive component (12) by comparing the resistance value of the resistive component (12) with the resistance value of a reference component, the reading block (14) having a reading current flowing through it; and • c. a control block (16) which is configured to generate an additional current and add said additional current to the reading current in order to obtain a resulting current flowing through the resistive component.
G11C 29/02 - Détection ou localisation de circuits auxiliaires défectueux, p. ex. compteurs de rafraîchissement défectueux
G11C 11/16 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments magnétiques utilisant des éléments dans lesquels l'effet d'emmagasinage est basé sur l'effet de spin
G06F 7/58 - Générateurs de nombres aléatoires ou pseudo-aléatoires
G11C 14/00 - Mémoires numériques caractérisées par des dispositions de cellules ayant des propriétés de mémoire volatile et non volatile pour sauvegarder l'information en cas de défaillance de l'alimentation
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITÉ GRENOBLE ALPES (France)
UNIVERSITÉ SAVOIE MONT BLANC (France)
UNIVERSITÉ CLERMONT AUVERGNE (France)
Inventeur(s)
Point, Sébastien
Beroud, Maïlys
Khazaz, Sarah
Mondillon, Laurie
Mermillod, Martial
Abrégé
Security lighting device (1) comprising a front face (3) for displaying a pictogram, a rear face and at least one thick wall (5) extending between the front face and the rear face, said security lighting device comprising first light means designed to illuminate the front face (3), said lighting device (1) being characterized in that it further comprises second light means installed on said at least one thick wall (5), said second light means being controlled such that the emitted light has a flashing frequency of between 5 Hz and 24 Hz adapted to influence the decision of the user on the chosen direction of evacuation.
G09F 13/04 - Enseignes, tableaux ou panneaux éclairés de derrière l'illustration
G09F 9/37 - Dispositifs d'affichage d'information variable, dans lesquels l'information est formée sur un support, par sélection ou combinaison d'éléments individuels dans lesquels le ou les caractères désirés sont formés par une combinaison d'éléments individuels à éléments mobiles
G09F 19/22 - Moyens de publicité ou de présentation sur des routes, des murs ou des surfaces similaires, p. ex. éclairés
49.
HALOGENATED SALICYLANILIDE DERIVATIVES AS USP8 INHIBITORS FOR THERAPEUTIC USES
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Fauvarque, Marie-Odile
Waltrich Augusto, Thierry
Mortier, Magda
Barette, Caroline
Abrégé
The invention relates to compounds of general formula (I): for use for treating an adrenocorticotropin hormone (ACTH)-dependent Cushing's syndrome, wherein R1is H or a -C(O)-R9, wherein R9133 linear or branched, saturated or unsaturated, alkyl group; R2is H or a halogen; R3is a halogen; R4and R8are, independently, H or a halogen, R5133, linear or branched, saturated or unsaturated, alkyl group, OH, or a halogen; R6610133 linear or branched, saturated or unsaturated, alkyl group; R713261010 aryl group, Ar being optionally substituted with a halogen, wherein if R2is H, then at least one of R5, R6, R7and R8 is not H,or one of its pharmaceutically acceptable salts.
A61K 31/198 - Alpha-amino-acides, p. ex. alanine ou acide édétique [EDTA]
A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
A61P 5/06 - Médicaments pour le traitement des troubles du système endocrinien des hormones de l'hypophyse antérieure, p. ex. TSH, ACTH, FSH, LH, PRL, GH
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
50.
SYSTEM FOR HELPING DIAGNOSING AGGRESSIVE PROSTATE CANCERS AND RELATED METHOD
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
UNIVERSITE GRENOBLE ALPES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
HOSPICES CIVILS DE LYON (France)
CENTRE LEON BERARD (France)
UNIVERSITÉ CLAUDE BERNARD LYON 1 (France)
Inventeur(s)
Souchon, Rémi
Jaouen, Tristan
Hoang-Dinh, Au
Gonindard, Christelle
Rouviere, Olivier
Abrégé
The invention relates to a system and a method for computer-aided detection (CAD) of aggressive prostate cancers. The automatic diagnosis of aggressive prostate cancers is difficult and methods that work with some MRI scanners do not work as well when implemented on images from different scanners. By studying a data base containing MRI data and biopsy results from 265 patients, acquired by 4 different types of MRI scanners, using machine learning techniques, the inventors established a method for automatically determining the presence of aggressive cancers, this methods showing high sensitivity and specificity when implemented on another database containing MRI data from 270 patients, acquired by different MRI scanners than the first database. The method involves feeding MRI images to a system calculating a score for a portion of the prostate and determines that the portion contains an aggressive cancer based on whether a criterion depending on the score is verified.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITÉ GRENOBLE ALPES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Savin, Valentin
Goswami, Ashutosh-Kumar
Mhalla, Mehdi
Abrégé
The present invention concerns a quantum processing system (1) configured to implement a transversal action of a logical T gate on a triply even quantum code (Q1) or a triply even quantum polar code (Q2) encoding K logical qubits into N physical qubits wherein the logical T gate is a tensorproduct of K elementary logical gates acting on the corresponding K logical qubits.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Lenormand, Jean-Luc
Reynaud, Déborah
Abrégé
The invention relates to new cell-penetrating peptides comprising or consisting of an amino acid sequence selected from the sequences SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 and SEQ ID NO: 8. The invention further relates to fusion proteins comprising said peptides and a molecule of pharmaceutical, diagnostic or biotechnological interest.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Houchmandzadeh, Bahram
Ballet, Patrice
Abrégé
According to an aspect, the present description is related to an apparatus for depositing on a substrate drops of a specimen sample including a liquid medium and living microorganisms. The apparatus includes a tray for supporting the substrate, a container, e.g. a syringe, configured to receive a volume of the specimen sample and a drop deposition motor configured to push the specimen sample out of the container to form drops of a predetermined volume that detach by gravity and fall on the substrate. The apparatus further includes guiding motors configured for changing a relative position of the tray and the container and a control unit configured to synchronize the drop deposition motor and the guiding motors in order to deposit drops on the substrate according to a pattern.
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
Inventeur(s)
Zebda, Abdelkader
Cinquin, Philippe
Ben Tahar, Awatef
Coizet, Véronique
Abrégé
A transdermal dihydrogen delivery device including a body including an anode and a cathode, and an electrical energy source, wherein the body is based on a flexible material, capable of shaping to the skin of a human or animal body, and the body includes a water receptacle, the relative arrangement of the receptacle, the anode and the cathode being configured such that the water contained in the receptacle is in contact with the anode and the cathode to form a closed electrical circuit, so as to produce dihydrogen at the cathode from the water taken from the receptacle, to release transdermally the dihydrogen produced. The proposed delivery device is relatively non-invasive, while allowing dihydrogen delivery.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Neagoie, Carmen
Ioana, Cornel
Abrégé
nkk) defined by a frequency range, for which a value representative of the power spectral density of the signal (x) is greater than a percentage (A) of its average value.
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Won, Yuho
Kim, Yongwook
Reiss, Peter
Saha, Avijit
Yadav, Ranjana
Abrégé
A nanocrystal particle includes a Group III-VI compound including gallium and sulfur, wherein the nanocrystal particle is configured to emit a first light, a maximum emission peak of the first light is in a wavelength range of greater than or equal to about 300 nanometers and less than or equal to about 485 nanometers, an absolute quantum efficiency of the nanocrystal particle is greater than or equal to about 26%, and a full width at half maximum of the maximum emission peak of the first light is greater than or equal to about 10 nanometers and less than or equal to about 70 nanometers, when analyzed by photoluminescence spectroscopy.
C09K 11/64 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant de l'aluminium
C09K 11/62 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du gallium, de l'indium ou du thalium
G02F 1/1335 - Association structurelle de cellules avec des dispositifs optiques, p. ex. des polariseurs ou des réflecteurs
H10K 50/115 - OLED ou diodes électroluminescentes polymères [PLED] caractérisées par les couches électroluminescentes [EL] comprenant des nanostructures inorganiques actives, p. ex. des points quantiques luminescents
H10K 59/38 - Dispositifs spécialement adaptés à l'émission de lumière multicolore comprenant des filtres de couleur ou des supports changeant de couleur [CCM]
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
UNIVERSITE SAVOIE MONT BLANC (France)
CNRS (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Pinton, Eric
Bultel, Yann
Drugeot, Timothée
Micoud, Fabrice
Abrégé
A method may activate a fuel cell including a plurality of electrochemical cells in a stack, the fuel cell being intended to operate, during at least one nominal operating phase, as an electric generator. Such a method may include, during an activation phase by electrolysis, prior to the at least one nominal operating phase: electrically supplying the fuel cell by an external electric generator, the electric supply being configured to apply an activation voltage greater than the voltage of the cell in an open circuit (OCV); fluid supplying a humid gas fluid at a first electrode and/or a second electrodes. The humid gas may have a relative humidity (RH) such that 40%≤RH<100%. The fuel cell may operate in electrolysis during the activation phase called by electrolysis.
H01M 8/04225 - Dispositions auxiliaires, p. ex. pour la commande de la pression ou pour la circulation des fluides pendant le démarrage ou l’arrêtDépolarisation ou activation, p. ex. purgeMoyens pour court-circuiter les éléments à combustible défectueux pendant le démarrage
H01M 4/86 - Électrodes inertes ayant une activité catalytique, p. ex. pour piles à combustible
H01M 8/04089 - Dispositions pour la commande des paramètres des réactifs, p. ex. de la pression ou de la concentration des réactifs gazeux
H01M 8/04119 - Dispositions pour la commande des paramètres des réactifs, p. ex. de la pression ou de la concentration des réactifs gazeux avec apport simultané ou évacuation simultanée d’électrolyteHumidification ou déshumidification
H01M 8/04223 - Dispositions auxiliaires, p. ex. pour la commande de la pression ou pour la circulation des fluides pendant le démarrage ou l’arrêtDépolarisation ou activation, p. ex. purgeMoyens pour court-circuiter les éléments à combustible défectueux
H01M 8/0656 - Combinaison d’éléments à combustible avec des moyens de production de réactifs ou pour le traitement de résidus avec des moyens de production des réactifs gazeux par des moyens électrochimiques
H01M 8/1004 - Éléments à combustible avec électrolytes solides caractérisés par les ensembles membrane-électrodes [MEA]
58.
ANTISENSE OLIGONUCLEOTIDES FOR THEIR USE IN AN ANTI-CANCER TREATMENT
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (France)
CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE (France)
Inventeur(s)
Humbert, Sandrine
Agasse, Fabienne
Saudou, Frédéric
Rayane, Kassem
Abrégé
An antisense oligonucleotides having the ability to decrease the expression level of the huntingtin protein in glioma cells, for their use in sensitizing the cells to an anti-cancer treatment.
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61K 31/166 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome de carbone d'un groupe carboxamide lié directement au cycle aromatique, p. ex. procaïnamide, procarbazine, métoclopramide, labétalol
A61K 31/175 - Amides, p. ex. acides hydroxamiques ayant le groupe N-C(O)-N ou N-C(S)-N, p. ex. urée, thiourée, carmustine ayant le groupe , N-C(O)-N=N- ou , p. ex. carbonohydrazides, carbazones, semicarbazides, semicarbazonesLeurs thio-analogues
A61K 31/495 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec deux azote comme seuls hétéro-atomes d'un cycle, p. ex. pipérazine
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Fernandes Caçoilo, Nuno-Filipe
Prejbeanu, Ioan-Lucian
Fruchart, Olivier
Dieny, Bernard
Sousa, Ricardo
Abrégé
Disclosed is a method to fabricate a magnetic device (4) from a dielectric layer (3) having a through-hole, so called "via", the method comprising: • - forming a tunnel junction (41) on the dielectric layer (3) comprising: • - a first magnetic layer, intended to form a said "free layer" (411); and • - a second magnetic layer, intended to form a said "reference layer" (412), • - an insulator layer, intended to form a "tunnel barrier" (413); the free layer (411) or the reference layer (412) being located in the via and being surrounded by the dielectric layer (3).
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Fernandes Caçoilo, Nuno-Filipe
Prejbeanu, Ioan-Lucian
Fruchart, Olivier
Dieny, Bernard
Sousa, Ricardo
Abrégé
A magnetic tunnel junction (3) is disclosed which includes a synthetic antiferromagnetic free layer structure (30) comprising a magnetic core (32) and a magnetic shell (31), the magnetic core comprising a magnetic layer (321) having an aspect ratio between 0.5 and 2, the magnetic shell surrounding the magnetic core at least partially along its thickness, and the magnetization of the magnetic shell being antiferromagnetically coupled with the magnetization of the magnetic core. A corresponding fabrication method is also disclosed.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Marcatel, Etienne
Lebret, Kevin
Elbaz-Vincent, Philippe
Abrégé
A computer-implemented method for memory management in a computer system configured for generating a signature of a binary data message m using a key B of a predetermined lattice-based structure is proposed, which comprises: determining coefficients of a 2×2 signature generation matrix SG, wherein the non-diagonal coefficients of the signature generation matrix SG are complex polynomials with a non-zero imaginary part, and the diagonal coefficients of the signature generation matrix SG are real polynomials; and determining a LDL representation of the signature generation matrix SG according to which SG is represented by a matrix product L.D.L*, wherein L is a 2×2 lower triangular matrix with ones on the diagonal, D is a 2×2 diagonal matrix, and L* is the adjoint of L; wherein the storing in a memory buffer of the computer system of the coefficients of the signature generation matrix SG and the coefficients of the matrices of the LDL representation is managed based on that the signature generation matrix SG has real diagonal coefficients, and the memory buffer is used alternatively to store the coefficients of the signature generation matrix SG or the coefficients of the matrix D of the LDL representation.
H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
62.
CRYSTALLINE HAFNIUM OXIDE NANOPARTICLES, METHOD FOR MANUFACTURING SAME, AND USES THEREOF
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (France)
ECOLE NORMALE SUPERIEURE DE LYON (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Chaput, Frederic
Lerouge, Frederic
Karpati, Szilvia
Bulin, Anne-Laure
Abrégé
Disclosed are crystalline hafnium oxide nanoparticles, a method for manufacturing same, and the uses thereof. The invention relates to crystalline hafnium oxide nanoparticles, characterized in that they bear amide molecules and/or at least one amide degradation product chosen from a carboxylic acid, an amine or an amino acid and/or residues of said molecules on their surface.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITÉ SAVOIE MONT BLANC (France)
Inventeur(s)
Pavlenko, Ekaterina
Jordy, Christian
Bouchet, Renaud
Mangani, Léa
Isaac, James
Devaux, Didier
Abrégé
The present application relates to ceramic/polymer hybrid solid electrolytes with improved interfacial strength, comprising a surface-dehydrated pre-treated ceramic.
H01M 10/056 - Accumulateurs à électrolyte non aqueux caractérisés par les matériaux utilisés comme électrolytes, p. ex. électrolytes mixtes inorganiques/organiques
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
UNIVERSITE SAVOIE MONT BLANC (France)
Inventeur(s)
Martin, Guillerme
Morand, Alain
Abrégé
The invention relates to an optical substrate (1) having an integrated waveguide (2), at least one antenna (330) being formed in the optical substrate (1), the at least one antenna being formed by a plurality of nanoholes (341, 342, 343), at least one of the nanoholes (341, 342, 343) differing from the other nanoholes (341, 342, 343) by at least one of: its diameter, its spacing of the waveguide (2) in the height direction of the optical substrate (1), and its distance from an adjacent nanohole of the same antenna in the longitudinal direction of the optical substrate (1). The invention also relates to a spectrometer (S) that integrates an optical substrate (1) of this kind.
G02B 6/12 - Guides de lumièreDétails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p. ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
B82Y 20/00 - Nano-optique, p. ex. optique quantique ou cristaux photoniques
G02B 6/124 - Lentilles géodésiques ou réseaux intégrés
G02B 6/293 - Moyens de couplage optique ayant des bus de données, c.-à-d. plusieurs guides d'ondes interconnectés et assurant un système bidirectionnel par nature en mélangeant et divisant les signaux avec des moyens de sélection de la longueur d'onde
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE DE BORDEAUX (France)
INSTITUT POLYTECHNIQUE DE BORDEAUX (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Chevalier, Xavier
Sérégé, Matthieu
Gomes Correia, Cindy
Zelsmann, Marc
Fleury, Guillaume
Abrégé
The invention relates to a method of directional self-assembly lithography, said method comprising a step of depositing a block copolymer film on a layer (20) neutral with respect the block copolymer, said block copolymer film being for use as a lithography mask, said method being characterized in that it comprises the following steps of:
depositing said neutral layer (20) on a surface of a substrate (10), said neutral layer (20) being of the carbon or fluoro-carbon type deposited to a thickness greater than 1.5 times the thickness of the block copolymer film (40),
crosslinking said neutral layer,
depositing said block copolymer film, comprising at least one silylated block, on said crosslinked neutral layer (30),
subjecting the stack to an assembly temperature in order to nanostructure said block copolymer,
removing (G1) at least one of the nano-domains (41, 42) from the nanostructured block copolymer film (40), in order to create a pattern intended to be transferred by etching (G2, G3, G4) into the thickness of the substrate (10).
G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
66.
METHOD FOR DETERMINING THE OPERATING STATE OF A LIGHT-EMITTING IMPLANT
Commissariat à l'Energie Atomique et aux Energies Alternatives (France)
CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Bleuet, Pierre
Chabrol, Claude
Moro, Cécile
Chabardes, Stephan
Benabid, Alim Louis
Abrégé
A method for determining the operating state of a light-emitting implant implanted in the brain of a living being, the light-emitting implant including a light source responsible for emitting light into the brain of the living being, the method using a diagnosing device that includes a receiver of a light signal transmitted through a first eye of the living being and a device for determining the operating state of the light-emitting implant based on the received transmitted light signal.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE DE LORRAINE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Cosnier, Serge
Mc Murtry, Stefan
El Mazria, Omar
Riahi, Hanna
Nedellec, Yannig
Abrégé
An electrode including a storage film. The storage film includes a layer of a support material including at least one inclusion in which a compound of interest is stored and a wall of permeable sealing material sealing the at least one inclusion. The storage film further includes a porous layer covering, at least in part, the wall of sealing material, at least a portion of a surface of the porous layer constituting an active surface of the electrode.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Le Goff, Alan
Sorrentino, Ilaria
Abrégé
A method for the detection of polycyclic aromatic hydrocarbons including: a) a step of contacting an aqueous solution including at least one polycyclic aromatic hydrocarbon with a catalyst for the oxidation of polycyclic aromatic hydrocarbons and with an electrode made of a conductive porous material, and b) a step of detecting the anthraquinone that is formed during the previous step through the oxidation of the polycyclic aromatic hydrocarbons.
C12Q 1/26 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une oxydoréductase
C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITÉ GRENOBLE ALPES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Savin, Valentin
Goswami, Ashutosh-Kumar
Mhalla, Mehdi
Abrégé
The present invention concerns a method and a system of fault tolerant preparation of quantum polar code states, comprising: -a set of single qubit Pauli measurement circuits (3) configured to prepare an initial quantum system 5 of N = 2n single-qubit states associated to an initial quantum base, -a set of two qubit Pauli measurement circuits (7) configured to recursively prepare a quantum polar code |q2n)s °f codelength N = 2n, wherein at each recursive level k, where k = 1 to n, a set of 2n/2k quantum polar code states ||<72fc) j(k) = 1 to 2n/2k of codelengths 2k, siW referenced by corresponding sets Sj^ of indices comprising first and second sets of frozen indices = [17, ■ ■■, i7(k)} and X7(k) = {(i + !);(/<),..., 27k k)} is prepared, each quantum polar code state |q2k) being prepared by the application of two qubit Pauli measurement P ® P circuits on two equivalent polar code states 2^ ) 01 aanndd belonging to the output of the antecedent recursive level k — 1 and referenced by two corresponding sets of iinnddiicceess
G06N 10/20 - Modèles d’informatique quantique, p. ex. circuits quantiques ou ordinateurs quantiques universels
G06N 10/70 - Correction, détection ou prévention d’erreur quantique, p. ex. codes de surface ou distillation d’état magique
G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p. ex. couplage ou commande de qubit
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Duda, Andrzej
Mkacher, Faten
Abrégé
The present disclosure relates to a time client device comprising a network interface for communicating over a communication network, the time client device being configured to: receive, over the communication network from an authentication server (AS), a first key, and a first value containing the first key in encrypted form; generate a second value using the first key; and during a time synchronization phase, transmit to a time server (TS) the first and second values.
H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
71.
COMPACT CALIBRATED INTERFEROMETRIC CHARACTERISATION SYSTEM
G01N 21/27 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en utilisant la détection photo-électrique
G01N 21/77 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique
G01N 21/45 - RéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant des méthodes interférométriquesRéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant les méthodes de Schlieren
72.
METHOD FOR ESTIMATING A CONCENTRATION OF GAS EMITTED BY A MEDIUM
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
UNIVERSITE GRENOBLE ALPES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Grangeat, Pierre
Comsa, Maria-Paula
Koenig, Anne
Phlypo, Ronald
Abrégé
The invention relates to a method for estimating the content of a gas-of-interest in a medium using a measurement device intended to be placed in contact with the medium, the device extending between a contact face intended to be applied against the medium and a distal end, the device comprising a side wall extending between the contact face and the distal end, and the device comprising: on the contact face, at least one intake opening configured to collect the gas-of-interest emitted by the medium, the intake opening extending through the contact face; a measurement chamber comprising a gas sensor, the gas sensor being configured to measure a concentration of the gas-of-interest flowing through the measurement chamber; a collection chamber (30) connected to the measurement chamber and delimited by the side wall, the collection chamber comprising at least one side opening (34) extending through the side face so as to admit ambient air into the collection chamber.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
A61B 5/083 - Mesure du taux de métabolisme en utilisant un essai respiratoire, p. ex. mesure du taux de consommation d'oxygène
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
A61B 5/1477 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques non invasifs
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
73.
DEVICE FOR MODIFYING THE DIRECTION OF MAGNETIZATION OF A MAGNETIC LAYER, ASSOCIATED METHOD AND SPINTRONIC SYSTEM
Commissariat à l'énergie atomique et aux énergies alternatives (France)
THALES (France)
Centre national de la recherche scientifique (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Attane, Jean-Philippe
Vila, Laurent
Bibes, Manuel
Abrégé
A device for modifying at least the direction of magnetization of a magnetic layer, the modifying device including a ferroelectric layer having a ferroelectric polarization, arranged on or under the magnetic layer so as to define a stack including at least the magnetic layer and the ferroelectric layer, a generator apt to inject an electric current into the stack along a direction parallel to the plane of the layers of the stack, and a modification unit apt to modify the ferroelectric polarization of the ferroelectric layer, for modifying, with the generator, the direction of magnetization of the magnetic layer.
G11C 11/16 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments magnétiques utilisant des éléments dans lesquels l'effet d'emmagasinage est basé sur l'effet de spin
G11C 19/08 - Mémoires numériques dans lesquelles l'information est déplacée par échelons, p. ex. registres à décalage utilisant des éléments magnétiques utilisant des couches minces dans une structure plane
H10B 61/00 - Dispositifs de mémoire magnétique, p. ex. dispositifs RAM magnéto-résistifs [MRAM]
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES (France)
UNIVERSITE DE BOURGOGNE (France)
Inventeur(s)
Sanchez, Lionel
Monna, Fabrice
Pepin, Jean-Louis
Abrégé
A process for determining a patient's apnoea+hypopnoea index or statis dependent on this index, including supplying a data set relating to a patient having, or making it possible to determine, characteristic data of the patient's maxillofacial morphology. The determination of the characteristic data is dependent on the positioning of at least four homologous points (1100, 1110), on a 3D scan of the head (60) of the patient (6). The process includes introducing this set into a machine learning model, trained to predict the apnoea+hypopnoea index, or the status, for the data set, from a database of different patients including maxillofacial morphology data, associated with an apnoea+hypopnoea index, or a status dependent on an apnoea+hypopnoea index, such that the model predicts an apnoea+hypopnoea index or a status for the data set relating to the patient.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
Centre National de la Recherche Scientifique (France)
Université Grenoble Alpes (France)
Inventeur(s)
Vieille, Victor
Devillers, Thibaut
Abrégé
The invention relates to a system and an implementation method for pumping a fluid, the system comprising:
a pump comprising a flexible membrane which has two opposing surfaces, the membrane comprising a spatially rotating permanent magnetization structure, a rigid support means to which at least a portion of the lower surface of the membrane is attached,
a source of a magnetic field which is capable of generating a magnetic drive field at the location of the membrane, the magnetic drive field having a substantially homogeneous orientation.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Leprince, Maxime
Auzely, Rachel
Texier-Nogues, Isabelle
Abrégé
A polymer of hyaluronic acid modified by the grafting thereto of at least one of the functions —SO3− and aromatic rings may be used as dopant for a polymer formed from one or monomers chosen from EDOT, ProDOT, and derivatives thereof. An aqueous suspension, or ink, and materials, in particular hydrogels, based on at least one PEDOT and/or PProDOT polymer may be doped by at least one such modified hyaluronic acid polymer. Such modified hyaluronic acid polymers may be used in bioelectronic or biosensor devices.
C08B 37/08 - ChitineSulfate de chondroïtineAcide hyaluroniqueLeurs dérivés
C08J 3/24 - Réticulation, p. ex. vulcanisation, de macromolécules
C08L 65/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant une liaison carbone-carbone dans la chaîne principaleCompositions contenant des dérivés de tels polymères
C09D 11/102 - Encres d’imprimerie à base de résines artificielles contenant des composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Kriekouki, Ioanna
Galy, Philippe
Pioro-Ladriere, Michel
Abrégé
The present invention relates to an electronic device (1) comprising a silicon-on-insulator strip (100) laterally defined by insulating trenches (106); a first gate (112) supported by the strip; a second gate (114), or a third gate (116), parallel to the strip (100), supported by the strip and being separated from the first gate (112) a first gap (e1) or a second gap (e2); two first semiconductor regions (110), or two second semiconductor regions (108), doped and arranged along and on either side of the second gate (114) or the third gate (116); at least one fourth gate (122A, 122B), or at least one fifth gate (126A, 126B), arranged facing the first gap (e1) or the second gap (e2); and a region (130) for biasing a substrate under the strip.
H01L 29/06 - Corps semi-conducteurs caractérisés par les formes, les dimensions relatives, ou les dispositions des régions semi-conductrices
H01L 29/423 - Electrodes caractérisées par leur forme, leurs dimensions relatives ou leur disposition relative ne transportant pas le courant à redresser, à amplifier ou à commuter
H01L 29/66 - Types de dispositifs semi-conducteurs
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
Inventeur(s)
Ghodhbane, Myriam
Beneventi, Davide
Chaussy, Didier
Belgacem, Mohamed Naceur
Dubois, Lionel
Zebda, Abdelkader
Abrégé
A composition for manufacturing an electrode, the composition including an electrically conductive carbon-based compound, at least one species able to form a catalyst, and cellulose microfibrils encapsulating chitosan. The cellulose microfibrils create a fibrous mesh binding the composition while limiting coating of the catalyst. Thus, the catalyst remains accessible to the surrounding environment, to allow the redox reactions at the electrode. The electrochemical performances of the electrode are consequently improved. The composition is furthermore particularly adapted for shaping an electrode by 3D printing.
Commissariat à I'Énergie Atomique et aux Énergies Alternatives (France)
Universite Grenoble Alpes (France)
Centre National de la Recherche Scientifique (France)
Inventeur(s)
Lausecker, Clément
Baillin, Xavier
Consonni, Vincent
Salem, Bassem
Abrégé
A method of forming nanowires, including the forming on a metal region of a layer having through openings, and the forming in the through openings of portions deposited in a chemical bath, forming all or part of the nanowires and extending from the metal region.
C23C 18/06 - Revêtement de parties déterminées de la surface, p. ex. au moyen de masques
C23C 18/12 - Revêtement chimique par décomposition soit de composés liquides, soit de solutions des composés constituant le revêtement, ne laissant pas de produits de réaction du matériau de la surface dans le revêtementDépôt par contact par décomposition thermique caractérisée par le dépôt sur des matériaux inorganiques, autres que des matériaux métalliques
C23C 18/08 - Revêtement chimique par décomposition soit de composés liquides, soit de solutions des composés constituant le revêtement, ne laissant pas de produits de réaction du matériau de la surface dans le revêtementDépôt par contact par décomposition thermique caractérisée par le dépôt d'un matériau métallique
80.
METHOD FOR THE SYNTHESIS OF NANOCAPSULES, COSMETIC COMPOSITION AND COSMETIC METHOD
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Saulais, Marlène
Dufresne, Alain
Sillard, Cécile
Abrégé
The invention relates to method for synthesising core-shell nanoparticles comprising an inorganic matrix core including a photolysable organic compound. The shell is advantageously biosourced, and the hybrid core can be removed by UV irradiation so as to obtain hollow nanoparticles.
A61K 8/58 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des atomes autres que des atomes de carbone, hydrogène, halogène, oxygène, azote, soufre ou phosphore
A61Q 1/10 - Préparations contenant des colorants cutanés, p. ex. pigments pour les yeux, p. ex. eye-liner, mascara
A61Q 1/12 - Poudres pour le visage ou le corps, p. ex. pour l'entretien, l'embellissement ou l'absorption
A61Q 3/00 - Préparations pour les soins des mains ou des pieds
A61Q 5/00 - Préparations pour les soins des cheveux
A61Q 19/00 - Préparations pour les soins de la peau
81.
METHOD FOR PREPARING POLY-BETA-HYDROXYALKANOATE FILMS
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Tramis, Olivier
El Kissi, Nadia
Roux, Denis
Abrégé
The application relates to a method for preparing a PHA film, comprising the steps consisting of: a) mixing a PHA in powder form and an aqueous solution in order to obtain a PHA suspension, b) leaving the PHA suspension to rest, by means of which a portion of the PHA settles out and a pellet is obtained, above which floats a supernatant, c) collecting at least part of the supernatant, d) applying the collected supernatant to at least one flat horizontal portion of a surface of a first substrate, e) evaporating the water from the applied supernatant, f) heating at least one region of the portion of the surface of the first substrate to which the supernatant was applied, by means of which a first substrate is obtained having said at least one region covered with a PHA film. PHA films from 1 to 60 µm thick can be obtained using this method.
C08J 3/05 - Production de solutions, dispersions, latex ou gel par d'autres procédés que ceux utilisant les techniques de polymérisation en solution, en émulsion ou en suspension dans un milieux aqueux à partir de polymères solides
METHOD FOR MEASURING THE OXIDATION POTENTIAL OF SAMPLES, IN PARTICULAR AEROSOLS, EQUIPMENT FOR THE IMPLEMENTION THEREOF AND USE OF SAME FOR ON-LINE ANALYSIS OF AIR QUALITY
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Uzu, Gaëlle
Jaffrezo, Jean-Luc
Freche, Guilhem
Abrégé
The present application relates to a method for the on-line and real-time automatic determination of the oxidization potential of an environment, enabling the air quality and/or the toxicity of the vapors emitted by various appliances or facilities to be analyzed.
The present application relates to a method for the on-line and real-time automatic determination of the oxidization potential of an environment, enabling the air quality and/or the toxicity of the vapors emitted by various appliances or facilities to be analyzed.
Figure for the abstract: None
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITE GRENOBLE ALPES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE RECHERCHE POUR L’AGRICULTURE, L’ALIMENTATION ET L’ENVIRONNEMENT (France)
Inventeur(s)
Le Moigne, Damien
Salvaing, Juliette
Amato, Alberto
Abrégé
The present invention relates to an engineered unicellular Stramenopile microalga comprising a loss of function of the homologous Seipin gene, an in vitro method of producing triacylglycerols (TAG), and uses thereof.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Guillet De Chatellus, Hugues
Bourdarot, Guillaume
Berger, Jean-Philippe
Abrégé
A wideband device for measuring the cross-correlation of a first signal and a second signal, includes a first frequency-shifting optical cavity comprising a first frequency shifter designed to shift the optical frequency of the first signal by a first frequency f1 per round trip in the first cavity, the first cavity having a first trip time τ1; a second frequency-shifting optical cavity comprising a second frequency shifter designed to shift the optical frequency of the second signal by a second frequency f2 per round trip in the second cavity, the second cavity having a second trip time τ2; the first and the second optical cavity being designed such that a maximum number of round trips of the first and the second signal in the first and the second cavity is equal to predetermined N, a detector designed to coherently detect the first signal transmitted by the first cavity and the second signal transmitted by the second cavity and generate a photocurrent (Tr) proportional to a luminous intensity detected by the detector, a low-pass filter designed to filter frequencies of the photocurrent that are lower than min (I), a processor configured to compute a Fourier transform of the photocurrent, so as to generate an output signal that is representative (II).
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (France)
CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES (France)
Inventeur(s)
Weissenhorn, Winfried
Sulbaran Machado, Guidenn
Guilligay, Delphine
Effantin, Gregory
Amen, Axelle
Poignard, Pascal
Le Grand, Roger
Maisonnasse, Pauline
Abrégé
A recombinant SARS-CoV-2 S glycoprotein ectodomain trimer is disclosed, including three recombinant protomers each containing at least the SARS-CoV-2 S glycoprotein ectodomain, and wherein: in each protomer, the furin cleavage site is inactivated/disrupted; Arg408 of one of the protomers is covalently linked to Lys378 of another one of the protomers; and Lys947 of one of the protomers is covalently linked to Arg1019 and/or to Lys776 of another one of the protomers.
C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61P 31/14 - Antiviraux pour le traitement des virus ARN
86.
DEVICE FOR WIDE-BAND SPECTRAL ANALYSIS OF A SIGNAL OF INTEREST
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Guillet De Chatellus, Hugues
Abrégé
A wideband device for the spectral analysis of a signal of interest includes a source designed to generate the signal of interest; an optical splitter element designed to spatially split the signal of interest into a first signal and a second signal; a first frequency-shifting optical cavity comprising a first frequency shifter designed to shift the optical frequency of the first signal by a first frequency f1 per round trip in the first cavity, the first cavity having a first trip time τ1; a second frequency-shifting optical cavity comprising a second frequency shifter designed to shift the optical frequency of the second signal by a second frequency f2 per round trip in the second cavity, the second cavity having a second trip time τ2; the first and the second optical cavity being designed such that a maximum number of round trips of the signal in the first and the second cavity is equal to predetermined N; a detector designed to coherently detect the first signal transmitted by the first cavity and the second signal transmitted by the second cavity and generate a photocurrent proportional to a luminous intensity detected by the detector, an analog low-pass filter designed to filter frequencies of the photocurrent that are lower than min (f12/; f2/2) a processor configured to compute a square modulus of the photocurrent filtered by the low-pass filter, from which a temporal representation of frequency information of the signal of interest is determined.
COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (France)
UNIVERSITÉ GRENOBLE ALPES (France)
Inventeur(s)
Vermeersch, Rémy
Daudin, Bruno
Abrégé
X1(1-X1-Y1)Y1X2(1-X2-Y2)Y2Y2N doped according to a second type of conductivity, opposite to the first type of conductivity, where X2 > 0 and X2+Y2 ≤ 1, the emissive portion being arranged between the portion of the first type and the portion of the second type.
H01L 33/32 - Matériaux de la région électroluminescente contenant uniquement des éléments du groupe III et du groupe V de la classification périodique contenant de l'azote
H01L 33/20 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué
H01L 33/18 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure cristalline ou une orientation particulière, p.ex. polycristalline, amorphe ou poreuse au sein de la région électroluminescente
H01L 33/00 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails
H01L 33/08 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une pluralité de régions électroluminescentes, p.ex. couche électroluminescente discontinue latéralement ou région photoluminescente intégrée au sein du corps semi-conducteur
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Avenas, Yvan
Bikinga, Wendpanga
Mezrag, Bachir
Abrégé
A power electronic system including a plurality of power components and a plurality of electrically-conductive heatsinks, each of said power components being disposed between two electrically-conductive heatsinks of the plurality of electrically-conductive heatsinks, at least one electrically-conductive heatsink being configured to be polarised according to a phase potential, called phase heatsink, at least one electrically-conductive heatsink being configured to be polarised according to a +DC potential, called cathode heatsink, and at least one electrically-conductive heatsink configured to be polarised according to a −DC potential, called anode heatsink, the system further includes at least one external phase connection, and at least one external +DC connection, and at least one external −DC connection respectively connected to the phase heatsink, to the cathode heatsink and to the anode heatsink.
H05K 7/20 - Modifications en vue de faciliter la réfrigération, l'aération ou le chauffage
H05K 9/00 - Blindage d'appareils ou de composants contre les champs électriques ou magnétiques
H02M 7/00 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant continuTransformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif
89.
PROTEOLIPOSOMES COMPRISING A SARS-COV-2 S GLYCOPROTEIN ECTODOMAIN AND THEIR USE AS A VACCINE
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIE ALTERNATIVES (France)
CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES (France)
Inventeur(s)
Weissenhorn, Winfried
Sulbaran Machado, Guidenn
Guilligay, Delphine
Effantin, Gregory
Amen, Axelle
Poignard, Pascal
Le Grand, Roger
Maisonnasse, Pauline
Abrégé
A recombinant SARS-CoV-2 S glycoprotein ectodomain trimer is disclosed, comprising three recombinant protomers each containing at least the SARS- CoV-2 S glycoprotein ectodomain, and wherein: in each protomer, the furin cleavage site is inactivated/disrupted; Arg408 of one of said protomers is covalently linked to Lys378 of another one of said protomers; and Lys947 of one of said protomers is covalently linked to Arg1019 and/or to Lys776 of another one of said protomers.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Marin, Philippe
Furia, Gioia
Chaussy, Didier
Beneventi, Davide
Abrégé
A method for printing at least one conductive track on the surface of an object, using at least one arm robot and at least one conductive ink print head. The object being arranged in a working area of the robot including taking a 3D scan of the object using a scanner mounted on the arm of the robot which controls the movement relative to the object. A digital model of the scanned portion of the surface of the object is constructed. A conductive track 10 is drawn digitally on the previously constructed digital model. Depending on the drawing of the conductive track, a path for the print head is generated. The conductive track is printed using the print head mounted on the arm of the robot which controls the movement relative to the object, by following the previously generated path.
B41J 3/407 - Machines à écrire ou mécanismes d'impression ou de marquage sélectif caractérisés par le but dans lequel ils sont construits pour le marquage sur des matériaux particuliers
B05B 13/04 - Moyens pour supporter l'ouvrageDisposition ou assemblage des têtes de pulvérisationAdaptation ou disposition des moyens pour entraîner des pièces les têtes de pulvérisation étant déplacées au cours de l'opération
H05K 3/10 - Appareils ou procédés pour la fabrication de circuits imprimés dans lesquels le matériau conducteur est appliqué au support isolant de manière à former le parcours conducteur recherché
91.
METABOLIC MARKERS SPECIFIC TO NEURODEGENERATIVE DISEASES SUCH AS PARKINSON'S DISEASE AND USE THEREOF IN DIAGNOSIS
INSERM - Institut National de la Santé et de la Recherche Médicale (France)
Inventeur(s)
Boulet, Sabrina
Fauvelle, Florence
Mallet, David
Abrégé
An identification of novel combinations of specific metabolites for neurodegenerative diseases for use as biomarkers in the early diagnosis of neurodegenerative diseases.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Bonvalot, Marceline
Chevolleau, Thierry
Jaffal, Moustapha
Abrégé
The invention relates to a plasma-assisted deposition reactor (1) comprising a reaction chamber (10) that comprises: a plate (110) having an upper face (110a) for receiving a substrate (2); a gaseous precursor inlet (12) to the chamber (10); a pumping module (13) for the chamber (10); and a power source (14) configured to apply a radio frequency bias to the plate (110), wherein a side wall (100) of the chamber (10) is, at least in part, non-parallel to the upper face (110a) of the plate (110), and the upper face (110a) of the plate (110) and the side wall (100) are separated by a distance d configured to generate a plasma by capacitive coupling between the plate (110) and the side wall (100); the plasma is thus generated in a localised manner in the vicinity of the substrate with a low ion flux.
H01J 37/32 - Tubes à décharge en atmosphère gazeuse
H05H 1/46 - Production du plasma utilisant des champs électromagnétiques appliqués, p. ex. de l'énergie à haute fréquence ou sous forme de micro-ondes
C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
C23C 16/52 - Commande ou régulation du processus de dépôt
C23C 16/509 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement au moyen de décharges électriques utilisant des décharges à radiofréquence utilisant des électrodes internes
C23C 16/458 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour supporter les substrats dans la chambre de réaction
93.
METHOD FOR CAPACITIVELY COUPLED PLASMA DEPOSITION OF ATOMIC LAYERS
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Bonvalot, Marceline
Chevolleau, Thierry
Jaffal, Moustapha
Abrégé
The invention relates to a method (4) for plasma deposition of atomic layers and to the associated reactor, the method comprising loading (40) a substrate (2) into a plasma reactor (1) comprising a reaction chamber (10) and a plurality of cycles (41) of depositing atomic layers on the exposed surface (20) of the substrate (2), which method comprises: injecting, into the reaction chamber, a precursor based on a first species (410), treating the plasma (412) of the exposed surface (20) of the substrate (2) by means of a plasma generated by capacitive coupling between the plate (110) and the side wall (100) of the reaction chamber (10) by providing radiofrequency power to the plate (110). Capacitive coupling makes it possible to create a plasma located in the vicinity of the substrate having low and finely adjustable ion energy and density.
H01J 37/32 - Tubes à décharge en atmosphère gazeuse
H05H 1/46 - Production du plasma utilisant des champs électromagnétiques appliqués, p. ex. de l'énergie à haute fréquence ou sous forme de micro-ondes
C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
C23C 16/52 - Commande ou régulation du processus de dépôt
C23C 16/509 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement au moyen de décharges électriques utilisant des décharges à radiofréquence utilisant des électrodes internes
C23C 16/458 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour supporter les substrats dans la chambre de réaction
94.
ASTROCYTIC TRPA1 CHANNEL INHIBITION AS A NOVEL NEUROPROTECTIVE THERAPEUTIC TARGET IN THE PRODROMAL PHASES OF ALZHEIMER'S DISEASE
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
Inventeur(s)
Albrieux, Mireille
Paumier, Adrien
Bosson, Anthony
Buisson, Alain
Boisseau, Sylvie
Abrégé
A TRPA1 calcium channel inhibitor for use as a neuroprotectant in the treatment and/or prevention of the early stages of Alzheimer's disease and as an anti-inflammatory in the treatment and/or prevention of neuroinflammatory processes in Alzheimer's disease. In particular, the inhibitor HC030331 of the TRPA1 calcium channel for its use as a neuroprotectant in the treatment and/or prevention of the early stages of Alzheimer's disease and as an anti-inflammatory in the treatment and/or the prevention of the neuroinflammatory processes of Alzheimer's disease. A pharmaceutical composition comprising at least the inhibitor of the invention and at least one pharmaceutically acceptable excipient.
A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Picart, Catherine
Bettega, Georges
Bouyer, Michael
Abrégé
An implantable medical device for bone repair following a loss of bone substance including a scaffold having a three-dimensional structure and having at least one polymer, a film having at least one protein from the Bone Morphogenetic Proteins (BMP) family, including the scaffold defines an internal volume having a three-dimensional mesh delimiting pores, the pores being open and interconnected, the largest dimension of each pore being greater than 200 µm, the scaffold having a minimum porosity of 80%, and in that the film coats the three-dimensional mesh. Also relates to the field of implantable medical devices. One application concerns the field of repairing bone following a loss of bone substance. The disclosure is applicable to large-volume bone defects ranging from 2 cm3 to 15 cm3.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Institut Polytechnique de Grenoble (France)
UNIVERSITE GRENOBLE ALPES (France)
Université de Chambéry - Université Savoie Mont Blanc (France)
Inventeur(s)
Febvre, Pascal
Yilmaz, Ugur
Abrégé
The present description concerns a support (108) for an electronic die (110), comprising: a first printed circuit board (300); a first conductive region (310), intended to receive the die, located on a first surface (108i) of the first board; and a second conductive region (320), intended to receive a thermal connector (200), located on a second surface (108s) of the first board, opposite to the first surface, the first region being connected to the second region by at least one through conductive via (330), located vertically in line with the first region.
A method for producing nanostructures having a metal oxide shell, carried by a top face of a substrate whose greatest dimension is greater than or equal to 100 mm by MOCVD metalorganic chemical vapour deposition, including successive steps carried out in a reactor configured for MOCVD deposition of nucleation and growth. The nucleation step includes forming non-contiguous metal nuclei by depositing a metal by MOCVD using a metalorganic precursor on the top face of the substrate and oxidising the metal of the metal nuclei, to form oxidised nuclei and ensure stabilisation of the nuclei. The growth step includes depositing a metal by MOCVD using the metalorganic precursor, to form non-contiguous nanostructures by growth of the oxidised nanostructures, and oxidising the deposited metal of the nanostructures formed in the nucleation to form oxidised nanostructures.
C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
UNIVERSITE GRENOBLE ALPES (France)
Inventeur(s)
Barre, Stéphane
Delon, Antoine
Abrégé
-- A device for generating electric current in a fluid flow circuit, including a duct segment interposed in the fluid flow circuit, a rotor mounted in the duct segment and movable by the passage of a fluid through the device, and a stator or stator circuit cooperating with the rotor and producing electric current. The rotor is made up of a transverse flow turbine, the axis of rotation of which extends across the duct segment, the turbine having at the longitudinal ends of its axis of rotation means for holding against the opposite walls of the duct segment, the stator or stator circuit being positioned outside the duct segment at an end of the turbine which is able to be driven in rotation while the turbine moves, and includes structure for generating a magnetic flux for cooperating with the stator or stator circuit in order to produce the electric current.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITE GRENOBLE ALPES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
IFREMER - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER (France)
Inventeur(s)
Forge, Vincent
Champavert, Joffrey
Hurtaud, Julien
Goraguer, Herlé
Morozan, Adina
Abrégé
The invention relates to a method for electrochemically activating a material comprising hydronium ion-conducting amyloid fibres and glycosylated proteins, the method comprising at least one step that consists in placing at least part of said material in contact with a water vapour, electrolysing at least part of the water vapour which is in contact with said material, and obtaining an activated material. The invention also relates to an activated material obtained in this way and to the use thereof for generating electrical energy.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
UNIVERSITE GRENOBLE ALPES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Forge, Vincent
Champavert, Joffrey
Hurtaud, Julien
Rannou, Patrice
Abrégé
The present invention relates to the use of hydronium ion-conducting amyloid fibers or of wires comprising a plurality of hydronium ion-conducting amyloid fibers for generating electrical energy from a humid surrounding atmosphere. The invention also relates to a device comprising such fibers or wires.