CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
Inventeur(s)
Becquart, Frédéric
Carrot, Christian
Ghriga, Mohammed Abdelfetah
Abrégé
The invention relates to a method for extruding wood pellets, the method being characterized in that it comprises at least the steps of:
(a) providing pieces of wood;
(b) grinding and partially drying, in a twin-screw extruder including at least shear generating elements, pieces of wood to obtain wood particles having a reduced water content compared to the pieces of wood;
(c) compressing the particles and shaping in at least one die to obtain wood pellets.
The invention relates to a method for extruding wood pellets, the method being characterized in that it comprises at least the steps of:
(a) providing pieces of wood;
(b) grinding and partially drying, in a twin-screw extruder including at least shear generating elements, pieces of wood to obtain wood particles having a reduced water content compared to the pieces of wood;
(c) compressing the particles and shaping in at least one die to obtain wood pellets.
The invention also relates to a wood pellet capable obtained with this method and a co-rotating twin-screw extruder intended for the extrusion of wood pellets
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (France)
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
Inventeur(s)
Laurendeau, Matthieu
Jolivet, Frédéric
Gorges, Sébastien
Bernard, Guillaume
Rit, Simon
Desbat, Laurent
Abrégé
The invention relates to a method for reconstructing an object by x-ray tomography by means of x-ray sources and detectors. The method comprises the following steps: obtaining (EO) positions of the x-ray sources and detectors; pre-calculating (E1) a set of directions; calculating (E2) a tomographic incompleteness vector map; calculating (E3) a tomographic incompleteness map of the metrics IM(x); calculating (E4) regularization terms from the tomographic incompleteness vector map and from the tomographic incompleteness map of the metrics; and solving (E5), iteratively, a regularized tomographic reconstruction problem by means of the calculated regularization terms.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Jegou, Martin
Ganachaud, François
Barres, Claire
Abrégé
The present invention relates to a method for treating a material comprising one or more silicone elastomers, the method comprising a step of decrosslinking the material in the presence of a metal catalyst and of a solvent selected from the group consisting of alcohols, carboxylic acids, esters, ethers, and mixtures thereof, resulting in the formation of a mixture comprising fragmented chains of silicone elastomer.
C08J 11/22 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation par traitement avec une substance organique par traitement avec des composés organiques contenant de l'oxygène
C08G 77/38 - Polysiloxanes modifiés par post-traitement chimique
C08J 11/24 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation par traitement avec une substance organique par traitement avec des composés organiques contenant de l'oxygène contenant des groupes hydroxyle
C08J 11/26 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation par traitement avec une substance organique par traitement avec des composés organiques contenant de l'oxygène contenant des groupes acide carboxylique, leurs anhydrides ou esters
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Tillement, Olivier
Lux, François
Grea, Thomas
Grange, Coralie
Aigle, Axel
Roudier, Anouk
David, Laurent
Montembault, Alexandra
Tillement, Augustin
Passieux, Renaud
Salazar Ariza, Juan Felipe
Abrégé
The present invention relates to the field of compositions comprising a polymer bearing a chelating group capable of chelating one or more metals, and to the various uses thereof. In particular, the present invention relates to compositions comprising a copolysaccharide carrying a chelating group, which compositions may be in the form of a gel, as well as to the threads obtained from this gel.
Institut National des Sciences Appliquées Lyon (INSA Lyon) (France)
UNIVERSITE DE LORRAINE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Leroy, Marie-Alix
Pupier, Christophe Gérard
Dassonneville, Solène
Steyer, Philippe
Borroto, Alejandro
Bruyère, Stéphanie
Pierson, Jean-François
Prudent, Mathilde
Colombier, Jean-Philippe
Bourquard, Florent
Garrelie, Florence
Abrégé
A process for generating nanoparticles on the surface of a substrate includes a step of providing the substrate made of a material including at least one element from columns 4, 5, 13 and 14 of the periodic classification, and at least one noble or transition metal; a step of irradiating the substrate by laser, with a pulse duration between 1 fs and 100 ps, a pulse between 0.01 J/cm2 and 100 J/cm2, a wavelength between 100 nm and 5000 nm, and a number of pulses per point between 1 and 1000; and a step of generating at least one nanoparticle on the surface of the substrate, the at least one nanoparticle including at least the noble or transition metal, and having a different chemical composition from that of the substrate. Also disclosed is a part including such nanoparticles.
B23K 26/352 - Travail par rayon laser, p. ex. soudage, découpage ou perçage pour le traitement de surface
B23K 26/00 - Travail par rayon laser, p. ex. soudage, découpage ou perçage
B23K 26/0622 - Mise en forme du faisceau laser, p. ex. à l’aide de masques ou de foyers multiples par commande directe du faisceau laser par impulsions de mise en forme
6.
METHOD OF GENERATING A PALETTE FOR USE IN A PRINTING PROCESS AND PRINTING METHOD
CENTRE NATIONAL DE LA RECHERCHE SCENTIFIQUE (France)
UNIVERSITÉ JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Ayala, Stéphane
Destouches, Nathalie
Hèbert, Mathieu
Dalloz, Nicolas
Doan Le, Van
Abrégé
A method of generating a reduced palette for use in a printing process is disclosed. In the method, a plurality of images obtainable by varying printing parameters of the printing apparatus are printed, and color values of the same are measured. Based on the color values, a clustering is performed to obtain a plurality of clusters having similar color values. For each cluster, one or more representative images are selected to form the palette. In this manner, images with color values both inside a convex hull and on the convex hull can be included in the palette.
G06K 15/02 - Dispositions pour produire une présentation visuelle permanente des données de sortie utilisant des imprimantes
G06K 15/12 - Dispositions pour produire une présentation visuelle permanente des données de sortie utilisant des imprimantes par impression photographique
G06T 7/90 - Détermination de caractéristiques de couleur
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Lhost, Olivier
Navez, Pascal
Trolez, Yves
Cassagnau, Philippe
Abou-Taha, Mohammad
Delage, Karim
Abrégé
22 ranging from 10.0 to 600.0 g/10 min as determined according to ISO 1133-2011 at 230 °C under a load of 2.16 kg; an Mz below 1,000,000 g/mol as determined by size exclusion chromatography; an Mw/Mn ranging from 2.2 to 10.0 as determined by size exclusion chromatography a ratio of complex viscosity at a frequency of 0.01 rad/sec to the complex viscosity at a frequency of 100 rad/sec of at most 8.0, said ratio being measured at 190°C; and a tan delta at 0.1 rad at 190°C above 2.5.
B29C 45/00 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet
B29C 48/275 - Récupération ou réutilisation d’énergie ou de matière
B29C 48/40 - Moyens pour plastifier ou homogénéiser la matière à mouler ou pour la forcer dans la filière ou la matrice utilisant des vis entourées par un fourreau coopérant, p. ex. des extrudeuses à vis simple utilisant au moins deux vis parallèles, p. ex. extrudeuses à vis doubles
B29C 48/57 - Vis pourvues d’éléments de malaxage de type disque, p. ex. avec des éléments de forme ovale
B29C 48/625 - Vis caractérisées par le ratio longueur de filetage de la vis/diamètre externe [ratio L/D]
B29C 48/80 - Traitement thermique de la matière à mouler par extrusion ou des pièces ou des couches préformées, p. ex. par chauffage ou refroidissement dans la zone de plastification, p. ex. par chauffage des cylindres
B29C 48/875 - Traitement thermique de la matière à mouler par extrusion ou des pièces ou des couches préformées, p. ex. par chauffage ou refroidissement pour une répartition non uniforme de la température, p. ex. en utilisant des fourreaux ayant à la fois des zones de refroidissement et de chauffage
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Lhost, Olivier
Navez, Pascal
Trolez, Yves
Cassagnau, Philippe
Abou-Taha, Mohammad
Delage, Karim
Abrégé
A process to produce a polymer composition comprising providing from 10 to 90 wt.% of a component A being one or more polypropylene resins; from 90 to 10 wt.% of a component B being one or more materials having a polar functional group, polymers having a polar functional group, natural fibres, and any mixture thereof; and from 0.5 to 20 wt.% of a compatibilizer, and melt blending the components and the compatibilizer to obtain a polymer composition; wherein the compatibilizer is a grafted blend of polyethylene and polypropylene comprising from 5 to 90 wt.% of polyethylene, has a melt index MI2 ranging from 5.0 to 200.0 g/10 min according to ISO 1133-2011 at 190 °C under a load of 2.16 kg a complex viscosity at 0.1 rad/sec at 190 °C of at most 1,000 Pa·s; and a grafting agent content ranging from 0.3 to 5.0 wt.%.
C08F 255/02 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères d'hydrocarbures tels que définis dans le groupe sur des polymères d'oléfines contenant deux ou trois atomes de carbone
C08F 299/02 - Composés macromoléculaires obtenus par des interréactions de polymères impliquant uniquement des réactions entre des liaisons non saturées carbone-carbone, en l'absence de monomères non macromoléculaires à partir de polycondensats non saturés
C08J 3/00 - Procédés pour le traitement de substances macromoléculaires ou la formation de mélanges
C08J 3/20 - Formation de mélanges de polymères avec des additifs, p. ex. coloration
C08F 8/46 - Réaction avec des acides dicarboxyliques non saturés ou avec leurs anhydrides, p. ex. maléinisation
C08L 23/28 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères modifiées par post-traitement chimique par réaction avec les halogènes ou des composés contenant des halogènes
9.
PROCESS FOR TREATMENT OF AN INITIAL POLYPROPYLENE-CONTAINING MATERIAL TO PRODUCE A POLYPROPYLENE COMPOSITION FOR INJECTION MOLDING
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Lhost, Olivier
Navez, Pascal
Trolez, Yves
Cassagnau, Philippe
Abou-Taha, Mohammad
Delage, Karim
Abrégé
The disclosure provides a process for the treatment of an initial polypropylene-containing material to produce a polypropylene composition comprising the steps of providing a twin screw extruder with thermal regulation devices; providing an initial polypropylene-containing material comprising at least 50 wt.% of polypropylene; extruding the initial polypropylene- containing material to obtain a polypropylene composition; and recovering a polypropylene composition; wherein the step of extruding comprises a thermal treatment of the initial polypropylene-containing material at a maximum barrel temperature Ts of at least 345°C in one or more hot zones of the extruder by self-heating.
B29C 45/00 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet
B29C 48/275 - Récupération ou réutilisation d’énergie ou de matière
B29C 48/40 - Moyens pour plastifier ou homogénéiser la matière à mouler ou pour la forcer dans la filière ou la matrice utilisant des vis entourées par un fourreau coopérant, p. ex. des extrudeuses à vis simple utilisant au moins deux vis parallèles, p. ex. extrudeuses à vis doubles
B29C 48/57 - Vis pourvues d’éléments de malaxage de type disque, p. ex. avec des éléments de forme ovale
B29C 48/625 - Vis caractérisées par le ratio longueur de filetage de la vis/diamètre externe [ratio L/D]
B29C 48/80 - Traitement thermique de la matière à mouler par extrusion ou des pièces ou des couches préformées, p. ex. par chauffage ou refroidissement dans la zone de plastification, p. ex. par chauffage des cylindres
B29C 48/875 - Traitement thermique de la matière à mouler par extrusion ou des pièces ou des couches préformées, p. ex. par chauffage ou refroidissement pour une répartition non uniforme de la température, p. ex. en utilisant des fourreaux ayant à la fois des zones de refroidissement et de chauffage
B29B 7/48 - MélangeMalaxage continu, avec dispositifs mécaniques de mélange ou de malaxage avec dispositifs de mélange ou de malaxage mobiles rotatifs avec plus d'un arbre à dispositifs à engrènement, p. ex. à vis qui s'engrènent
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Lhost, Olivier
Navez, Pascal
Trolez, Yves
Cassagnau, Philippe
Abou-Taha, Mohammad
Delage, Karim
Beyou, Emmanuel
Abrégé
The disclosure relate to a process for grafting a polypropylene-containing material to produce a modified polypropylene composition comprising the steps of providing an extruder with thermal regulation devices; providing a polypropylene-containing material comprising at least 50 wt.% of polypropylene based on the total weight of the polypropylene-containing material; providing a grafting agent in a content ranging from 0.8 to 10.0 wt.% based on the total weight of the polypropylene-containing material provided in step (b), wherein the grafting agent comprises at least one double bound per molecule; extruding the polypropylene-containing material and the grafting agent to obtain a modified polypropylene composition; wherein said step comprises a thermal treatment of the polypropylene-containing material at a maximum barrel temperature Ts of at least 345 °C to at most 440°C in one or more hot zones of the extruder; and recovering a modified polypropylene composition.
C08F 8/46 - Réaction avec des acides dicarboxyliques non saturés ou avec leurs anhydrides, p. ex. maléinisation
C08F 255/02 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères d'hydrocarbures tels que définis dans le groupe sur des polymères d'oléfines contenant deux ou trois atomes de carbone
C08J 3/20 - Formation de mélanges de polymères avec des additifs, p. ex. coloration
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Lhost, Olivier
Navez, Pascal
Trolez, Yves
Cassagnau, Philippe
Abou-Taha, Mohammad
Delage, Karim
Beyou, Emmanuel
Abrégé
The disclosure provides a modified polypropylene composition comprising at least 50 wt.% of polypropylene based on the total weight of the modified polypropylene composition, remarkable in that the modified polypropylene composition has a melt index MI2 ranging from 10.0 to 600.0 g/10 min as determined according to ISO 1133- 2011 at 230 °C under a load of 2.16 kg, an Mz below 1,000,000 g/mol as determined by size exclusion chromatography, a ratio of complex viscosity at a frequency of 0.01 rad/sec to the complex viscosity at a frequency of 100 rad/sec of at most 8.0, said ratio being measured at 190°C, a tan delta at 0.1 rad at 190°C above 2.5; and a grafting agent content of at least 0.3 wt.% based on total weight of the modified polypropylene composition.
C08F 8/46 - Réaction avec des acides dicarboxyliques non saturés ou avec leurs anhydrides, p. ex. maléinisation
C08F 255/02 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères d'hydrocarbures tels que définis dans le groupe sur des polymères d'oléfines contenant deux ou trois atomes de carbone
C08J 3/20 - Formation de mélanges de polymères avec des additifs, p. ex. coloration
12.
ORGANIC REINFORCEMENT OF AN ELASTOMER WITH THE IN SITU SYNTHESIS OF A POLYIMIDE PHASE BY REACTIVE EXTRUSION
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Cassagnau, Philippe
Delage, Karim
Bounor-Legare, Véronique
Marestin, Catherine
Dubois, Charlotte
Garois, Nicolas
Abrégé
The present disclosure relates to a process to produce a reinforced elastomeric material and to the reinforced elastomeric material. The process comprises the steps of providing components comprising a grafted elastomer, one or more dianhydrides, and one or more diamines; wherein the grafted elastomer is provided at a content of at least 60 wt.% based on the total weight of the components; performing in situ synthesis of a polyimide phase in the grafted elastomer by reactive extrusion of the components in a twin-screw extruder comprising main hopper wherein the screw profile comprises two or more reverse conveying elements forming two or more hot zones to form an elastomer-polyimide blend; and recovering said elastomer-polyimide blend being a reinforced elastomeric material.
C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
C08L 23/26 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères modifiées par post-traitement chimique
C08L 51/00 - Compositions contenant des polymères greffés dans lesquels le composant greffé est obtenu par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carboneCompositions contenant des dérivés de tels polymères
C08L 51/06 - Compositions contenant des polymères greffés dans lesquels le composant greffé est obtenu par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carboneCompositions contenant des dérivés de tels polymères greffés sur des homopolymères ou des copolymères d'hydrocarbures aliphatiques ne contenant qu'une seule liaison double carbone-carbone
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
HOSPICES CIVILS DE LYON (France)
Inventeur(s)
Cosset, Benoit
Abrégé
A fenestrated endoprosthesis of the thoracic aorta including a first mesh of stents, a main tubular endoprosthesis made of fabric, the main tubular endoprosthesis being rigidly attached to the first mesh, and having an arcuate central portion configured to be received in the aortic arch of a patient, the arcuate central portion extending between a first and a second end, each configured to be received respectively in a portion of the ascending or descending aorta, respectively. The fenestrated endoprosthesis further includes a flange also made of fabric and associated with a second mesh of stents, the flange having a substantially frustoconical shape and having a base, the base of the flange being mounted on an opening made in the upper face of the arcuate central portion, the flange being configured to be received at the base of the supra-aortic trunks of the patient.
A61F 2/89 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles les éléments filiformes comprenant au moins deux anneaux adjacents reliés de manière flexible par des éléments séparés
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
Centre national de la recherche scientifique (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Macchione, Silvia
Farne, Alessandro
Dinse, Hubert R.
Salemme, Roméo
Muret, Dollyane
Abrégé
System (101) of tactile stimulations, corresponding method and computer program product. The system is configured to generate tactile stimulations, the generation times of which follow a Poisson distribution with a lambda parameter comprised between 0.5 and 1.5.
A61H 23/02 - Massage par percussion ou vibration, p. ex. en utilisant une vibration ultrasoniqueMassage par succion-vibrationMassage avec des membranes mobiles à entraînement électrique ou magnétique
15.
CARBONATION OF EPOXIDIZED POLYMERS OR OLIGOMERS BY REACTIVE EXTRUSION
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Chalamet, Yvan
Guerdener, Bruno
Bounor-Legare, Véronique
Dufaud-Niccolai, Véronique
Raynaud, Jean
Monteil, Vincent
Ayzac, Virgile
Besognet, Paul
Abrégé
22 in the presence of a quaternary ammonium halide so as to form cyclic carbonate groups. This method may be included in a plastic recycling method, or may be followed by post-treatment steps.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE DE STRASBOURG (France)
CENTRE HOSPITALIER UNIVERSITAIRE (France)
Inventeur(s)
Gain, Philippe
Thuret, Gilles
Courrier, Emilie
He, Zhiguo
Ulrich, Gilles
De Nicola, Antoinette
Maurin, Corantin
Maret, Corentin
Abrégé
The invention relates to fluorescein derivative compounds and the use thereof as fluorescent markers. Said markers can be used in particular in biology and in medicine, particularly in the field of ophthalmology. The non-fluorescent fluorescein derivatives are activated in the cell, thereby allowing the detection of living cells as well as the quantification of cell viability by fluorescence, without being toxic to cells.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Sharma, Nipun
Flores Figueroa, Manuel Alejandro
Destouches, Nathalie
Vocanson, Francis
Abrégé
A personalizable security document (1) includes a laser- engravable film (2) formed on a layer (6) of the security document (1) as a functional layer, which can be irradiated with laser light of a specific wavelength to form a color image. The functional layer includes metallic nanoparticles (20) that can be excited with the laser light of a specific wavelength to promote a growth, reshaping, or reorganization of the nanoparticles, which results in a change in the color of the laser-engravable film (2) that can be observed, for example, in one or more observation modes. The laser-engravable film (2) is provided as a thin film in the nanometer range, which is very difficult to tamper with.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITÉ JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Cheiney, Pierrick
Robin, Thierry
Melin, Gilles
Balcon, Nicolas
Mekki, Julien
Girard, Sylvain
Abrégé
This relates to a dosimeter including a light source capable of generating a light beam, an optical coupler-splitter, a radio-sensitive optical fiber, a first photodetector arranged to record a power measurement of the light beam transmitted through the radio-sensitive optical fiber, a reference optical arm, a second photodetector arranged to record a reference power measurement of the light beam transmitted through the reference optical arm, and an electronic system configured to extract a differential radiation induced attenuation measurement in the radio-sensitive optical fiber with respect to the reference optical arm. The light beam is non-polarized or depolarized, or, respectively, the light beam is polarized and the radio-sensitive optical fiber is a polarization-maintaining fiber.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (France)
Inventeur(s)
Sexton, Alexane
Williams, Maud
Jevic, Julie
Espuche, Eliane
Gouanve, Fabrice
Abrégé
A transparent, gas-permeable and waterproof film, particularly for applications in the medical field is disclosed. The film includes a polyolefin base, to which is added a monomeric plasticiser with a percentage by mass of between 10% and 50% and preferably also molecular sieves with a percentage by mass of less than or equal to 20%, this addition enables in particular the gas permeability of the film to be increased, said film thus having a high gas permeability, as well as low water permeability and high transparency, together with various mechanical characteristics and properties so that it is particularly well suited to many applications, in particular in the medical sector and in particular for application to an identification card used in the medical diagnosis.
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE JEAN MONNET SAINT-ETIENNE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Lux, François
Tillement, Olivier
Si-Mohamed, Salim
Douek, Philippe
Boussel, Loïc
Le Duc, Géraldine
Abrégé
The present invention relates to a method for imaging an anatomical structure in a subject in need thereof, comprising the following steps: a) providing an injectable pharmaceutical composition comprising, as a contrast agent, at least one nanoparticle having a mean hydrodynamic diameter below 10 nm and comprising:. a biocompatible matrix, such as polyorganosiloxane,. at least one chelating agent covalently bonded to said biocompatible matrix,. at least one element having a Z of at least 40, chelated to at least a part of the chelating agents, b) injecting an effective amount of said pharmaceutical to said subject, and, c) acquiring an imaging scan of an anatomical structure of said subject in need thereof, by Spectral Photon Counting Computed Tomography (SPCCT) scanning.
A61K 49/04 - Préparations de contraste pour rayons X
A61K 49/08 - Préparations de contraste pour la résonance magnétique nucléaire [RMN]Préparations de contraste pour l'imagerie par résonance magnétique [IRM] caractérisées par le support
A61K 49/18 - Préparations de contraste pour la résonance magnétique nucléaire [RMN]Préparations de contraste pour l'imagerie par résonance magnétique [IRM] caractérisées par un aspect physique particulier, p. ex. émulsions, microcapsules, liposomes
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
B82Y 5/00 - Nanobiotechnologie ou nanomédecine, p. ex. génie protéique ou administration de médicaments
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Lhost, Olivier
Trolez, Yves
Navez, Pascal
Cassagnau, Philippe
Abou-Taha, Mohammad
Delage, Karim
Beyou, Emmanuel
Abrégé
The disclosure relates to a process to produce a polymer composition comprising melt blending from 10 to 90 wt.% of polyethylene resins; from 90 to 10 wt.% of materials selected from materials having a polar functional group, inorganic polar particles, polymers having a polar functional group, HD silica, fumed silica, carbon-containing particles, carbon fibres, glass fibres, natural fibres, and any mixture thereof; from 0.5 to 20 wt.% of a grafted polyethylene, and the compatibilizer is comprising at least 70 wt.% of polyethylene based on the total weight of the compatibilizer, and has a melt index MI2 ranging from 25 to 450.0 g/10 min, an Mw/Mn ranging from 2.0 to 4.5; a complex viscosity at 0.1 rad/sec at 190 °C of at most 25,000 Pa·s; and a grafting agent content ranging from 0.5 to 15.0 wt.% based on the total weight of the compatibilizer.
C08F 255/02 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères d'hydrocarbures tels que définis dans le groupe sur des polymères d'oléfines contenant deux ou trois atomes de carbone
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
22.
IMMUNOLOGICAL TEST FOR THE DETECTION OF VIRAL INFECTIONS
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
BIOSPEEDIA (France)
Inventeur(s)
Begaud, Evelyne
Germani, Yves
Pozzetto, Bruno
Bourlet, Thomas
Haddar, Cyrille Hedi
Pillet, Sylvie
Mounier, Sandra
Abrégé
The invention relates to a method for in vitro diagnosis of a viral infection due to the presence of a vims in a subject,
comprising a step of detecting at least one antigen specific for said vims by means of an immunological test carried out on a biological
sample from said subject, characterized in that said biological sample consists of a combination of saliva and secretions from the anterior
nasal vestibule of the subject.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
Centre National de la Recherche Scientifique (CNRS) (France)
Universite Jean Monnet Saint Etienne (France)
La Tannerie Vegetale (France)
Université Claude Bernard Lyon 1 (France)
Inventeur(s)
Deleage, Fanny
Chalamet, Yvan
Abrégé
The present disclosure relates to a method for the preparation, from a mixture comprising (i) plant proteins, (ii) one or more plant tanning agents, (iii) one or more plasticizers, of a biobased material that may resemble animal leather.
D06N 3/00 - Cuir artificiel, toile cirée ou matériau similaire obtenu par enduction de nappes fibreuses avec une substance macromoléculaire, p. ex. avec des résines, du caoutchouc ou leurs dérivés
C14C 3/26 - Tannage chimique par agents organiques au moyen d'autres substances organiques contenant des halogènes
24.
METHOD AND SYSTEM FOR CHARACTERISING MICROORGANISMS BY DIGITAL HOLOGRAPHIC MICROSCOPY
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Brault, Dylan
Fournier, Corinne
Olivier, Thomas
Faure, Nicolas
Abrégé
The invention relates to a method for characterising microorganisms present in a biological sample, the method comprising acquiring a live holographic digital image of the sample, generating a focused image by using a digital model for reconstructing the focused image and characterising the bacteria on the basis of the focused image. According to the invention, prior to the holographic image being acquired, a plurality of calibration objects are provided in the acquisition field of view, which objects have a previously characterised dimension and refractive index and a shape chosen so that the interference patterns of the objects can be calculated using an image forming model for incorporating optical aberrations of the acquisition device. Prior to the focused image being computer generated, the optical aberrations are qualified according to the interference patterns of the objects and the calculated interference patterns and the digital model for reconstructing the focused image incorporates the quantified optical aberrations.
G03H 1/00 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une imageLeurs détails spécifiques
G03H 1/04 - Procédés ou appareils pour produire des hologrammes
G03H 1/08 - Procédés ou appareils pour produire des hologrammes pour faire des hologrammes synthétiques
G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
G01N 15/10 - Recherche de particules individuelles
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
Inventeur(s)
Grange, Coralie
Aigle, Axel
Brichart, Thomas
Tillement, Olivier
Lux, François
David, Laurent
Ehrlich, Victor
Grea, Thomas
Salazar Ariza, Juan
Abrégé
The present disclosure relates to a functionalized statistic chitosan of weight average molecular mass between 100kDa and 1000kDa and of formula (I) wherein each Rc is independently a moiety comprising a chelating agent, each Z is independently a linker which is a single bond or a hydrocarbon chain containing between 1 and 12 carbon atoms, said hydrocarbon chain is linear or branched and optionally contains one or more unsaturations and one or more heteroatoms, preferably chosen from nitrogen, oxygen, sulfur and halogens, x is between 0.005 and 0.7, preferably between 0.05 and 0.7, y is between 0.01 and 0.7, preferably between 0.05 and 0.2, the ratio y/x being greater than or equal to 0.05, preferably greater than or equal to 0.15, and the sum x + y being greater than or equal to 0.15, preferably greater than or equal to 0.30, more preferably greater than or equal to 0.35, for use in the treatment of diseases characterized by local inflammation induced by and/or inducing a deregulation of metal homeostasis and increased oxidative stress, in a subject in need thereof.
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
C08B 37/08 - ChitineSulfate de chondroïtineAcide hyaluroniqueLeurs dérivés
COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (France)
Centre National De La Recherche Scientifique (CNRS) (France)
Universite Claude Bernard-Lyon1 (France)
Universite Jean Monnet Saint Etienne (France)
INSA Lyon (France)
Inventeur(s)
Sutter, Marc
Le Clerc, Christophe
Poloni, Melissa
Colella, Marion
Fenouillot-Rimlinger, Francoise
Bernard, Julien
Abrégé
A polyester comprises ethylene 2,5 furandicarboxylate units and diethylene glycol units, the polyester having a melting temperature Tf of greater than or equal to 225° C., an intrinsic viscosity of greater than or equal to 0.65 dL/g, and in which the amount of diethylene glycol unit, denoted DEG, is less than 4 mol % and the quantity of ester functions in chain end situations is less than 100 meq/kg. A process for producing the polyester is disclosed.
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT D'OPTIQUE (France)
Inventeur(s)
Gain, Philippe
Ain, Anthony
Thuret, Gilles
Lepine, Thierry
Abrégé
The invention relates to a device for examining the anterior part of the eye by retro-illumination of said anterior part. This device has means for illuminating the eye, comprising a light source (1), and means for imaging the anterior part of the eye. The invention consists in the device further comprising means of modulating at least one region of the light beam emitted from the light source (1).
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
28.
RAPID-CURING, LOW-TEMPERATURE COMPOSITION FOR THE PRODUCTION OF PRESSURISED TANKS MADE OF A COMPOSITE MATERIAL FOR THE ON-BOARD STORAGE OF HYDROGEN GAS
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (France)
VITECH COMPOSITES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD - LYON 1 (France)
UNIVERSITE JEAN MONET SAINT ETIENNE (France)
Inventeur(s)
Magnier, Christophe
Villalonga, Stéphane
Jegou, Martin
Livi, Sébastien
Gerard, Jean-François
Duchet-Rumeau, Jannick
Demaret, Frédéric
Abrégé
12344)+1234522)-53323222P(O)O]-. The invention also relates to the use of a composition (C) for the production of a hydrogen tank, in particular a type II, III, IV or V tank operating under pressure and comprising a composite material, for the on-board storage of hydrogen gas.
C08G 59/40 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les agents de durcissement utilisés
C08J 5/24 - Imprégnation de matériaux avec des prépolymères pouvant être polymérisés en place, p. ex. fabrication des "prepregs"
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ CLAUDE BERNARD - LYON 1 (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Meissirel, Claire
Bouvet, Pauline
Martin, Laurent
Salin, Paul
Abrégé
Inventors have shown evidence of VEGF accumulation in extracellular Aβ plaques in the post-mortem brain of patients with Alzheimer's disease (AD) and of the APP/PS1 mouse model of AD. They identified specific binding domains involved in the direct interaction between A0o and VEGF and engineered a peptide that blocks this interaction. The designed peptide binds to Aβ oligomers with high affinity and inhibits the process of Aβ self-aggregation, leading to the blockade of fibrillar aggregation. Furthermore, the peptide prevents soluble Aβ-derived toxins to target synapses in hippocampal neuron cultures and restores long-term potentiation in the hippocampus of the APP/PS1 mouse model of Alzheimer's disease. Thus, these findings have broad implications for preventing and treating diseases with Aβ neurotoxicity such as Alzheimer's disease. Accordingly, the invention relates to a peptide comprising the amino acid sequence KRKKSRYKSWSVYVG (SEQ ID NO: 1).
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61K 38/00 - Préparations médicinales contenant des peptides
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
30.
ANTI-ARGONAUTE PROTEIN AUTOANTIBODIES AS BIOMARKERS OF AUTOIMMUNE NEUROLOGICAL DISEASES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
HOSPICES CIVILS DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
INSERM (Institut National de la Sante et de la Recherche Medicale) (France)
Inventeur(s)
Do, Le Duy
Honnorat, Jerome
Pinto, Anne-Laurie
Moritz, Christian Peter
Antoine, Jean-Christophe
Camdessanche, Jean-Philippe
Muniz-Castrillo, Sergio
Abrégé
The invention relates to a process for identifying patients affected by an autoimmune neurological disease, comprising a step of detection of at least one type of anti-Argonaute autoantibodies (AGO-Abs) in a biological sample of an individual susceptible to be affected by said disease, wherein positive detection of said at least one type of AGO-Abs means that said individual is affected by said autoimmune neurological disease.
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
31.
MACHINE AND METHOD FOR TREATING PARTS OF DIFFERENT SHAPES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Heau, Christophe
Maurin-Perrier, Philippe
Garrelie, Florence
Colombier, Jean-Philippe
Pigeon, Florent
Abrégé
This invention relates to a machine for treating parts with different shapes, comprising a chamber); a vacuum system; treatment systems, including a plasma generating system and/or a vacuum deposition system; and a transport system which is capable of displacing the part or parts in the chamber irrespectively of the shape of these parts; characterized in that the treatment systems include a laser system which is designed to treat the part or parts disposed in the chamber.
B23K 26/00 - Travail par rayon laser, p. ex. soudage, découpage ou perçage
B01J 19/08 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage
B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage utilisant des radiations électromagnétiques
32.
PROCESS FOR THE PRODUCTION OF GRAFTED POLYETHYLENE AND GRAFTED POLYETHYLENE
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Lhost, Olivier
Navez, Pascal
Trolez, Yves
Cassagnau, Philippe
Abou-Taha, Mohammad
Delage, Karim
Beyou, Emmanuel
Abrégé
Process of grafting of a polyethylene-containing material to produce a modified polyethylene composition comprising providing a twin screw extruder with one or more thermal regulation devices; a polyethylene-containing material and a grafting agent and extruding the polyethylene-containing material and the grafting agent to obtain a modified polyethylene composition; the step of extruding comprises a thermal treatment of the polyethylene- containing material by self-heating of the material at a maximum barrel temperature Ts ranging from 315 °C to 410°C in one or more hot zones of the extruder.
C08F 255/02 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères d'hydrocarbures tels que définis dans le groupe sur des polymères d'oléfines contenant deux ou trois atomes de carbone
B29C 48/00 - Moulage par extrusion, c.-à-d. en exprimant la matière à mouler dans une matrice ou une filière qui lui donne la forme désiréeAppareils à cet effet
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ CLAUDE BERNARD LYON 1 (UCBL) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Lhost, Olivier
Trolez, Yves
Navez, Pascal
Cassagnau, Philippe
Delage, Karim
Abou-Taha, Mohammad
Abrégé
Polyethylene composition comprising at least 50 wt.% of polyethylene based on the total weight of the polyethylene composition, and having a density of at least 0.910 g/cm322 ranging from 3.0 to 60.0 g/10 min; an unsaturation index higher than 2,000 wherein the unsaturation index is the product of the Mn in Dalton and the vinyl unsaturation units per 1,000 carbon atoms as determined by ASTM D6248-98:2004; a complex viscosity at 0.1 rad/sec at 190° C ranging from 200 to 20,000 Pa·s; and a ratio of complex viscosity at a frequency of 0.01 rad/sec to the complex viscosity at a frequency of 100 rad/sec of at most 8.0, said ratio being measured at 190°C..
B29B 17/00 - Récupération de matières plastiques ou d'autres constituants des déchets contenant des matières plastiques
B29C 45/00 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet
B29C 48/275 - Récupération ou réutilisation d’énergie ou de matière
B29C 48/40 - Moyens pour plastifier ou homogénéiser la matière à mouler ou pour la forcer dans la filière ou la matrice utilisant des vis entourées par un fourreau coopérant, p. ex. des extrudeuses à vis simple utilisant au moins deux vis parallèles, p. ex. extrudeuses à vis doubles
B29C 48/57 - Vis pourvues d’éléments de malaxage de type disque, p. ex. avec des éléments de forme ovale
B29C 48/625 - Vis caractérisées par le ratio longueur de filetage de la vis/diamètre externe [ratio L/D]
B29C 48/80 - Traitement thermique de la matière à mouler par extrusion ou des pièces ou des couches préformées, p. ex. par chauffage ou refroidissement dans la zone de plastification, p. ex. par chauffage des cylindres
B29C 48/875 - Traitement thermique de la matière à mouler par extrusion ou des pièces ou des couches préformées, p. ex. par chauffage ou refroidissement pour une répartition non uniforme de la température, p. ex. en utilisant des fourreaux ayant à la fois des zones de refroidissement et de chauffage
34.
METHODS FOR PREDICTION AND MONITORING OF SPONTANEOUS PRETERM BIRTH
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
CHU DE ST ETIENNE (France)
COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA) (France)
UNIVERSITÉ GRENOBLE ALPES (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Alfaidy-Benharouga, Nadia
Benharouga, Mohamed
Chauleur, Céline
Barjat, Tiphaine
Abrégé
In the present invention, thanks to a prospective multicenter cohort study including 200 pregnant patients with five-serum sampling per patient, inventors investigated the concentrations of protein biomarkers in the plasma of high risk pregnant women during the second and third trimesters to predict spontaneous preterm birth. Inventors demonstrated that PROK1 (Prokineticin 1) also called EG-VEGF (Endocrine Gland-derived Vascular Endothelial Growth Factor), is secreted by the placenta and exhibits increased serum levels in patients with sPTB, before 37 weeks of gestation, compared with uncomplicated pregnant women. More precisely, Women with spontaneous preterm birth exhibited higher concentrations of serum PROK1/EG-VEGF than uncomplicated patients at 20 weeks, 24 weeks, 28 weeks and 32 weeks. Accordingly, serum PROK1/EG-VEGF concentrations could be considered as biomarker of spontaneous preterm birth in high-risk pregnant women.
G01N 33/74 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des hormones
35.
PROCESS FOR TREATMENT OF AN INITIAL POLYETHYLENE-CONTAINING MATERIAL TO PRODUCE A POLYETHYLENE COMPOSITION FOR INJECTION MOLDING
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITÉ CLAUDE BERNARD LYON 1 (UCBL) (France)
UNIVERSITÉ JEAN MONNET SAINT-ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (INSA LYON) (France)
Inventeur(s)
Lhost, Olivier
Trolez, Yves
Navez, Pascal
Cassagnau, Philippe
Delage, Karim
Abou-Taha, Mohammad
Abrégé
Process for treatment of an initial polyethylene-containing material to produce a polyethylene composition comprising providing a twin-screw extruder with thermal regulation devices; providing an initial polyethylene-containing material comprising at least 50 wt.% of polyethylene based on the total weight of the initial polyethylene-containing material; extruding the initial polyethylene-containing material to obtain a polyethylene composition; wherein extrusion is performed with a residence time of less than 20 min; and recovering a polyethylene composition; wherein extruding comprises a thermal treatment of the initial polyethylene-containing material at a temperature of at least 300°C in one or more hot zones of the extruder by self-heating to have a maximum barrel temperature ranging from 300 to 460°C in at least one hot zone of the extruder.
B29B 17/00 - Récupération de matières plastiques ou d'autres constituants des déchets contenant des matières plastiques
B29C 45/00 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet
B29C 48/275 - Récupération ou réutilisation d’énergie ou de matière
B29C 48/40 - Moyens pour plastifier ou homogénéiser la matière à mouler ou pour la forcer dans la filière ou la matrice utilisant des vis entourées par un fourreau coopérant, p. ex. des extrudeuses à vis simple utilisant au moins deux vis parallèles, p. ex. extrudeuses à vis doubles
B29C 48/57 - Vis pourvues d’éléments de malaxage de type disque, p. ex. avec des éléments de forme ovale
B29C 48/625 - Vis caractérisées par le ratio longueur de filetage de la vis/diamètre externe [ratio L/D]
B29C 48/80 - Traitement thermique de la matière à mouler par extrusion ou des pièces ou des couches préformées, p. ex. par chauffage ou refroidissement dans la zone de plastification, p. ex. par chauffage des cylindres
B29C 48/875 - Traitement thermique de la matière à mouler par extrusion ou des pièces ou des couches préformées, p. ex. par chauffage ou refroidissement pour une répartition non uniforme de la température, p. ex. en utilisant des fourreaux ayant à la fois des zones de refroidissement et de chauffage
36.
PHARMACEUTICAL FORMULATION FOR SUBCUTANEOUS ADMINISTRATION OF PROTEINS
GCS INSTITUT DE CANCEROLOGIE STRASBOURG EUROPE (France)
MEXBRAIN (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
Inventeur(s)
Detappe, Alexandre
Pivot, Xavier
Coliat, Pierre
Tillement, Olivier
Grea, Thomas
Lux, François
David, Laurent
Abrégé
The present invention relates to a pharmaceutical formulation of a pharmaceutically active protein comprising an effective amount of a protein or a combination of proteins, a chitosan A and at least one statistic polysaccharide B. It further relates to a kit comprising at least one first container containing the chitosan A and the statistic polysaccharide B and at least one second container containing the protein or combination of proteins. It further relates to the pharmaceutical formulation or the kit for use in the treatment of cancer, typically breast or gastric cancer.
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
ECOLE NATIONALE SUPERIEURE DES MINES DE SAINT ETIENNE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CHU DE ST ETIENNE (France)
Inventeur(s)
Marotte, Hubert
Dalix, Elisa
Abrégé
METHODS OF THERAPY COMPRISING SIMULTANEOUS ADMINISTRATION OF METHOTREXATE AND FOLIC ACID 5 Methotrexate (MTX) is an antineoplastic agent used the treatment of a wide variety of diseases including cancers and inflammatory autoimmune diseases such as psoriasis, Crohn's disease, and rheumatoid arthritis. Administered orally or by subcutaneous injection in low doses, MTX inhibits a number of folate dependent metabolic steps that lead to a state of effective folate 0 deficiency. It is likely that some of the adverse effects of MTX are due said folate deficiency, and the main factor affecting adherence to MTX is the occurrence of adverse effects, rather than lack of response. Although MTX side effects could be decreased by supplementation in folic acid (FA), the current guideline on folate administration is not precisely established. Now the inventors show that co-administration of MTX with FA on the same day is effective 5 compared to FA application one day after MTX. MTX metabolism was not affected, as demonstrated by the MTX-PG concentrations. The biological tolerance between the protocols was comparable. Thus, co-administration of MTX and FA seems to be possible and may be more convenient to the patients and improve compliance at the end.
SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON I (France)
UNIVERSITE JEAN MONNET SAINT-ETIENNE (France)
Inventeur(s)
Perie, Thomas
Lintingre, Eric
Auscher, Marie Camille
Buniazet, Zoé
Delaroa, Claire
Cassagnau, Philippe
Fulchiron, René
Abrégé
A binder for an injection moulding composition, the binder includes, in percentage by mass and for a total of 100%: 35% to 60% of a component (a), or polymer base, made of a polymer or a mixture of polymers, each of the polymer being non-amphiphilic and having a mass average molar mass greater than or equal to 5,000 g/mol, 30% to 55% of a component (b), or wax, made of a polymer or a mixture of polymers, each of the polymer being non-amphiphilic and having a mass average molar mass less than 5,000 g/mol, and less than 10% of an amphiphilic component (c), or surfactant, and less than 10% of other components (d). The polymer base comprising 2% to 15% of a styrene-ethylene-butylene-styrene copolymer (SEBS), in percentage by mass based on the mass of the binder.
Centre National de la Recherche Scientifique (CNRS) (France)
Inventeur(s)
Faure, Nicolas
Pinston, Frédéric
Fournier, Corinne
Denis, Loïc
Olivier, Thomas
Abrégé
A focus adjustment method for acquiring an image of a surface of interest of a sample by a holographic imager includes the steps of:
placing the sample including at least one reference object having a known shape and described by characterising parameters having at least position parameters
acquiring an image and determining the position of the reference object with respect to the acquisition plane, by applying a light diffraction model involving the spatial parameters of the reference object estimated by approximating the appearance of the reference object in the holographic image acquired, and
determining the position of the surface of interest with respect to the acquisition plane from a position of the reference object and focus adjustment of the image acquisition.
G03H 1/04 - Procédés ou appareils pour produire des hologrammes
G03H 1/02 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une imageLeurs détails spécifiques Détails
G03H 1/08 - Procédés ou appareils pour produire des hologrammes pour faire des hologrammes synthétiques
G03H 1/00 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une imageLeurs détails spécifiques
40.
METHOD OF GENERATING A MULTIPLEXED IMAGE FOR PRINTING
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Ayala, Stéphane
Destouches, Nathalie
Hébert, Mathieu
Dalloz, Nicolas
Abrégé
A method of generating a multiplexed image (18) for printing that can be observed in a plurality of modes includes determining a finite shape (22) of a multiplexed palette (10) in a combined color space. The contrast of the multiplexed image (18) in each mode can be optimized by determining a maximum volume hyperrectangle (20) enclosed in the finite shape (22). Gamut mapping to this maximum volume hyperrectangle (20) allows for generation of a multiplexed image (18) that has a maximum contrast and is free from artifacts caused by an interdependency between the colors in each mode. Performing a dimensionality reduction using PCA allows for reducing the complexity of the optimization problem.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE JEAN MONNET SAINT-ETIENNE (France)
Inventeur(s)
Tillement, Olivier
Tillement, Théodore
Lux, François
Rossetti, Fabien
Martini, Matteo
Der Nigohossian, Pierre
Hagege, Agnes
David, Laurent
Abrégé
The invention aims to provide an efficient method, in particular a computer-implemented method, for managing and/or monitoring the production of agricultural raw materials useful for the production of alcoholic beverages (e.g. wines), as well as the production, storage, ageing, consumption, quality, authenticity, traceability and/or selling price of these alcoholic beverages. To this end, the method according to the invention essentially consists in: (a) collecting two samples of the alcoholic beverage in an inert container sealed with an equally inert stopper; (b) assigning data on the alcoholic beverage to each sample; (c) storing at least some of the samples collected in step (a), under specified conditions; (d) analysing each sample to determine at least one mineral profile, preferably metallic; (e) forming a database relating to the samples and resulting from step (b) and step (d); (h) processing these data by statistical analysis, preferably using artificial intelligence tools; and (i) using the processed data to manage and/or monitor the entire supply chain of the alcoholic beverage until its consumption. The invention also relates to a device for implementing steps (a) and (c) of the method.
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Theil, Perrine
Fleury, Etienne
Baron, Marc
Abrégé
The present invention relates to a silicone composition X which is cross-linkable by polyaddition reactions to form a silicone elastomer. In particular, the present invention relates to a silicone composition X which is cross-linkable by irradiation, comprising at least one compound D selected from retinol, retinal, retinoic acid, retinol carboxylic acid esters, carotenes, and mixtures thereof.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
Inventeur(s)
Becquart, Frederic
Carrot, Christian
Ghriga, Mohammed Abdelfetah
Abrégé
The present invention relates to a process for the extrusion of wood pellets, comprising at least the steps of: (a) providing pieces of wood; (b) grinding and partially drying the pieces of wood in a twin-screw extruder comprising at least shear-generating elements, in order to obtain wood particles of which the water content is lower than that of the pieces of wood; (c) compressing the particles and shaping them in at least one die in order to obtain wood pellets. The invention also relates to wood pellets obtained by this process and to a co-rotating twin-screw extruder provided for the extrusion of wood pellets.
C10L 5/44 - Combustibles solides à base essentielle de matières d'origine non minérale de matières végétales
B29C 48/345 - Filières d’extrusion comprenant au moins deux orifices disposés de manière adjacente, pour extrusion simultanée de fils multiples, p. ex. pour faire des boulettes
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
Inventeur(s)
Becquart, Frédéric
Carrot, Christian
Ghriga, Mohammed Abdelfetah
Abrégé
The present invention relates to a process for the extrusion of wood pellets, comprising at least the steps of: (a) providing pieces of wood; (b) grinding and partially drying the pieces of wood in a twin-screw extruder comprising at least shear-generating elements, in order to obtain wood particles of which the water content is lower than that of the pieces of wood; (c) compressing the particles and shaping them in at least one die in order to obtain wood pellets. The invention also relates to wood pellets obtained by this process and to a co-rotating twin-screw extruder provided for the extrusion of wood pellets.
B27L 11/00 - Fabrication de copeaux, particules, poudre, ou produits similaires, à partir de boisOutils à cet effet
B29C 48/345 - Filières d’extrusion comprenant au moins deux orifices disposés de manière adjacente, pour extrusion simultanée de fils multiples, p. ex. pour faire des boulettes
RAPID-CURING COMPOSITION FOR THE PRODUCTION OF SEMI-FINISHED PRODUCTS ENABLING THE PRODUCTION OF COMPOSITE TYPE IV PRESSURE TANKS FOR THE ON-BOARD STORAGE OF HYDROGEN GAS
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (France)
VITECH COMPOSITES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD – LYON1 (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Magnier, Christophe
Villalonga, Stéphane
Jegou, Martin
Livi, Sébastien
Gerard, Jean-François
Duchet-Rumeau, Jannick
Demaret, Frédéric
Abrégé
The invention relates to a composition (C) comprising (A) 70 to 95 parts by weight of an epoxide resin having a viscosity of between 1 and 150 kPa.s at a temperature of between 20°C and 25°C, and (B) 5 to 30 parts by weight, per 100 parts by weight of resin present in the composition, of a curing agent dispersed in the resin, the curing agent being an ionic liquid containing a phosphonium cation. The invention also relates to a semi-finished product or towpreg, comprising a bundle of fibres (F) and a composition (C). The invention also relates to the use of a composition (C) or of a semi-finished product according to the invention for the production of a hydrogen tank, in particular a type IV pressure tank, made of composite material, for the on-board storage of hydrogen gas.
C08G 59/40 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les agents de durcissement utilisés
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Tillement, Olivier
Lux, François
Grea, Thomas
Grange, Coralie
Aigle, Axel
Roudier, Anouk
David, Laurent
Montembault, Alexandra
Tillement, Augustin
Passieux, Renaud
Salazar Ariza, Juan Felipe
Abrégé
The present invention relates to the field of compositions comprising a polymer bearing a chelating group capable of chelating one or more metals, and to the various uses thereof. In particular, the present invention relates to compositions comprising a copolysaccharide carrying a chelating group, which compositions may be in the form of a gel, as well as to the threads obtained from this gel.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES LYON (INSA LYON) (France)
Inventeur(s)
Leroy, Marie-Alix
Pupier, Christophe Gerard
Dassonneville, Solene
Steyer, Philippe
Borroto, Alejandro
Bruyere, Stephanie
Pierson, Jean-Francois
Prudent, Mathilde
Colombier, Jean-Philippe
Bourquard, Florent
Garrelie, Florence
Abrégé
The invention relates to a method for generating nanoparticles on the surface of a substrate, said method comprising: - a step of providing the substrate made of a material comprising at least one element from columns 4, 5, 13 and 14 of the periodic table, and at least one noble or transition metal; - a step of laser-irradiating the substrate with a pulse duration of between 1 fs and 100 ps, a fluence per pulse of between 0.01 J/cm2 and 100 J/cm2, a wavelength of between 100 nm and 5000 nm, and a number of pulses per point of between 1 and 1000; and - a step of generating at least one nanoparticle on the surface of the substrate, the at least one nanoparticle comprising at least the noble or transition metal, and having a chemical composition different from that of the substrate. The invention also relates to a part comprising such nanoparticles.
B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage utilisant des radiations électromagnétiques
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
B82Y 40/00 - Fabrication ou traitement des nanostructures
B23K 26/062 - Mise en forme du faisceau laser, p. ex. à l’aide de masques ou de foyers multiples par commande directe du faisceau laser
B23K 26/082 - Systèmes de balayage, c.-à-d. des dispositifs comportant un mouvement relatif entre le faisceau laser et la tête du laser
B23K 26/352 - Travail par rayon laser, p. ex. soudage, découpage ou perçage pour le traitement de surface
B23K 26/00 - Travail par rayon laser, p. ex. soudage, découpage ou perçage
C21D 10/00 - Modification des propriétés physiques autrement que par traitement thermique ou déformation
C22F 3/00 - Modification de la structure physique des métaux ou alliages non ferreux par des méthodes physiques particulières, p. ex. traitement par les neutrons
C23C 14/14 - Matériau métallique, bore ou silicium
C23C 14/16 - Matériau métallique, bore ou silicium sur des substrats métalliques, en bore ou en silicium
C23C 14/35 - Pulvérisation cathodique par application d'un champ magnétique, p. ex. pulvérisation au moyen d'un magnétron
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES LYON (INSA LYON) (France)
UNIVERSITE DE LORRAINE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Leroy, Marie-Alix
Pupier, Christophe Gérard
Dassonneville, Solène
Steyer, Philippe
Borroto, Alejandro
Bruyère, Stéphanie
Pierson, Jean-François
Prudent, Mathilde
Colombier, Jean-Philippe
Bourquard, Florent
Garrelie, Florence
Abrégé
The invention relates to a method for generating nanoparticles on the surface of a substrate, said method comprising: - a step of providing the substrate made of a material comprising at least one element from columns 4, 5, 13 and 14 of the periodic table, and at least one noble or transition metal; - a step of laser-irradiating the substrate with a pulse duration of between 1 fs and 100 ps, a fluence per pulse of between 0.01 J/cm2 and 100 J/cm2, a wavelength of between 100 nm and 5000 nm, and a number of pulses per point of between 1 and 1000; and - a step of generating at least one nanoparticle on the surface of the substrate, the at least one nanoparticle comprising at least the noble or transition metal, and having a chemical composition different from that of the substrate. The invention also relates to a part comprising such nanoparticles.
C23C 14/14 - Matériau métallique, bore ou silicium
B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage utilisant des radiations électromagnétiques
B23K 26/00 - Travail par rayon laser, p. ex. soudage, découpage ou perçage
B23K 26/062 - Mise en forme du faisceau laser, p. ex. à l’aide de masques ou de foyers multiples par commande directe du faisceau laser
B23K 26/082 - Systèmes de balayage, c.-à-d. des dispositifs comportant un mouvement relatif entre le faisceau laser et la tête du laser
B23K 26/352 - Travail par rayon laser, p. ex. soudage, découpage ou perçage pour le traitement de surface
C23C 14/35 - Pulvérisation cathodique par application d'un champ magnétique, p. ex. pulvérisation au moyen d'un magnétron
C22F 3/00 - Modification de la structure physique des métaux ou alliages non ferreux par des méthodes physiques particulières, p. ex. traitement par les neutrons
B82Y 40/00 - Fabrication ou traitement des nanostructures
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
C21D 10/00 - Modification des propriétés physiques autrement que par traitement thermique ou déformation
C23C 14/16 - Matériau métallique, bore ou silicium sur des substrats métalliques, en bore ou en silicium
COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON (France)
Inventeur(s)
Sutter, Marc
Leclerc, Christophe
Rousseau, Alain
Fenouillot-Rimlinger, Françoise
Bernard, Julien
Poloni, Melissa
Colella, Marion
Abrégé
The present invention relates to a method for preparing a furanic polyamide, comprising the following successive steps: a) a step of reacting a compound A of the following formula (I): with at least one compound B selected from the dicarboxylic acids, diesters and mixtures thereof, at a temperature less than or equal to 60°C, the molar ratio between the compound A and the compound(s) B ranging from 0.8 to 1.2, in order to obtain a salt; b) a step of poly-condensating the salt at a temperature Tb ranging from 125°C to 220°C when a single compound B is used in step a) and ranging from 125°C to 230°C when at least two compounds B are used in step a), and at a pressure P1 greater than or equal to the atmospheric pressure and strictly less than 5 bar for a first duration D1, then at a pressure P2 strictly less than the atmospheric pressure for a second duration D2.
C08G 69/26 - Polyamides dérivés, soit des acides amino-carboxyliques, soit de polyamines et d'acides polycarboxyliques dérivés de polyamines et d'acides polycarboxyliques
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
CENTRE LEO BERARD (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (UCBL) (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
Inventeur(s)
Lafon, Cyril
Catheline, Stefan
Thuret, Gilles
Lafond, Maxime
Gain, Philippe
Abrégé
The invention relates to a method for modifying elasticity properties of a soft material using ultrasound waves. The invention is particularly applicable to the human eye for the treatment of presbyopia by non-invasively modifying the stiffness of the crystalline lens. Ultrasound pulses generated with an ultrasonic transducer, such as a HIFU transducer, are focused on a target region of the material. The ultrasound pulses create cavitation bubbles in the target region, thus reducing the stiffness of the material.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
HOSPICES CIVILS DE LYON (France)
Inventeur(s)
Cosset, Benoit
Abrégé
The invention relates to a fenestrated endoprosthesis of the thoracic aorta comprising a first mesh of stents (2), a main tubular endoprosthesis (1) made of fabric, the main tubular endoprosthesis being rigidly attached to the first mesh, and having an arcuate central portion (12) configured to be received in the aortic arch of a patient, the arcuate central portion extending between a first (10) and a second (11) end, each configured to be received respectively in a portion of the ascending or descending aorta, respectively, the fenestrated endoprosthesis further comprising a flange (3) also made of fabric and associated with a second mesh of stents (4), the flange having a substantially frustoconical shape and having a base (30), the base of the flange being mounted on an opening (13) made in the upper face of the arcuate central portion (12), the flange (3) being configured to be received at the base of the supra-aortic trunks of the patient.
Centre National de la Recherche Scientifique (France)
Inventeur(s)
Kämpfe, Thomas
Dubost, Laurent
Sedao, Xxx
Abrégé
The present invention relates to an optical device (1) suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum, said device (1) comprising at least: a first coating layer (10) made of a first material, a substrate (50) made of a material that is different from the first material, and surface texturing (60) forming cavities (61) in the device (1); wherein a lower layer (50) disposed directly below the first coating layer (10) is either a second coating layer (20) made of a material that is different from the first material, or the substrate (50); wherein the lower layer (50) has a determined thickness (E50); characterised in that the cavities (61) extend through the coating layer (20) and are sunk into the lower layer (50) through at least part of the thickness (E50).
G02B 1/118 - Revêtements antiréfléchissants ayant des structures de surface de longueur d’onde sous-optique conçues pour améliorer la transmission, p. ex. structures du type œil de mite
Centre National de la Recherche Scientifique (France)
Inventeur(s)
Kämpfe, Thomas
Dubost, Laurent
Sedao, Xxx
Abrégé
The present invention relates to an optical device (1), suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum, said device (1) comprising at least: a substrate (10) made of a first material, a coating layer (20) made of a second material that is different from the first material, and surface texturing (30) forming cavities (31) in the device (1), characterized in that the cavities (31) extend through the coating layer (20) and are partially sunk into the substrate (10).
G02B 1/118 - Revêtements antiréfléchissants ayant des structures de surface de longueur d’onde sous-optique conçues pour améliorer la transmission, p. ex. structures du type œil de mite
G02B 1/12 - Revêtements optiques obtenus par application sur les éléments optiques ou par traitement de la surface de ceux-ci par traitement de la surface, p. ex. par irradiation
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE DE STRASBOURG (France)
CENTRE HOSPITALIER UNIVERSITAIRE (France)
Inventeur(s)
Gain, Philippe
Thuret, Gilles
Courrier, Emilie
He, Zhiguo
Ulrich, Gilles
De Nicola, Antoinette
Maurin, Corantin
Maret, Corentin
Abrégé
The invention relates to fluorescein derivative compounds and the use thereof as fluorescent markers. Said markers can be used in particular in biology and in medicine, particularly in the field of ophthalmology. The non-fluorescent fluorescein derivatives are activated in the cell, thereby allowing the detection of living cells as well as the quantification of cell viability by fluorescence, without being toxic to cells.
C12Q 1/44 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase une estérase
55.
METHOD FOR THE DETECTION OF PNEUMOCOCCAL INFECTION
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
BIOSPEEDIA (France)
Inventeur(s)
Pozzetto, Bruno
Begaud, Evelyne
Germani, Yves
Haddar, Cyrille
Carricajo, Anne
Abrégé
The present invention relates to a method for diagnosing in vitro a pneumococcal infection (Streptococcus pneumoniae), comprising at least two steps of detecting a pneumococcal antigen: (i) on a sample of secretions from the airways of a patient, and (ii) on the same sample after dilution.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Macchione, Sylvia
Farne, Alessandro
Dinse, Hubert R.
Salemme, Romeo
Muret, Dollyane
Abrégé
System (101) for generating tactile stimulations, corresponding method and computer program product. The system is configured to generate tactile stimulations the generation times of which follow a Poisson distribution with a lambda parameter comprised between 0.5 and 1.5.
A61H 23/02 - Massage par percussion ou vibration, p. ex. en utilisant une vibration ultrasoniqueMassage par succion-vibrationMassage avec des membranes mobiles à entraînement électrique ou magnétique
57.
IMMUNOLOGICAL TEST FOR THE DETECTION OF VIRAL INFECTIONS
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
BIOSPEEDIA (France)
Inventeur(s)
Begaud, Evelyne
Germani, Yves
Pozzetto, Bruno
Bourlet, Thomas
Haddar, Cyrille Hedi
Pillet, Sylvie
Mounier, Sandra
Abrégé
The invention relates to a method for in vitro diagnosis of a viral infection due to the presence of a virus in a subject, comprising a step of detecting at least one antigen specific for said virus by means of an immunological test carried out on a biological sample from said subject, characterized in that said biological sample consists of a combination of saliva and secretions from the anterior nasal vestibule of the subject.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
58.
IMMUNOLOGICAL TEST FOR THE DETECTION OF VIRAL INFECTIONS
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
BIOSPEEDIA (France)
Inventeur(s)
Begaud, Evelyne
Germani, Yves
Pozzetto, Bruno
Bourlet, Thomas
Haddar, Cyrille Hedi
Pillet, Sylvie
Mounier, Sandra
Abrégé
The invention relates to a method for in vitro diagnosis of a viral infection due to the presence of a virus in a subject, comprising a step of detecting at least one antigen specific for said virus by means of an immunological test carried out on a biological sample from said subject, characterized in that said biological sample consists of a combination of saliva and secretions from the anterior nasal vestibule of the subject.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
59.
METHOD FOR PRODUCING A PLURALITY OF IMPLANTS FROM A PREVIOUSLY REMOVED HUMAN OR ANIMAL CORNEA
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
CENTRE HOSPITALIER UNIVERSITAIRE (France)
Inventeur(s)
Gain, Philippe
Thuret, Gilles
Mauclair, Cyril
Albourgol, Samy
Egaud, Gregory
Abrégé
The invention concerns a cutting process for producing a plurality of implants from a previously removed human or animal cornea, wherein the process comprises the following steps:
depositing (200) the cornea in a holding device,
cutting (300), using a laser source, the cornea contained in the holding device to obtain a cut cornea,
detaching (400) each implant from the cut cornea,
decellularizing (500) each detached implant to obtain decellularized implants,
lyophilizing (600) each decellularized implant to obtain lyophilized implants,
sterilizing (700) each lyophilized implant to obtain sterilized implants,
packaging (800) each sterilized implant to obtain packaged implants.
The invention concerns a process for preparing an allograft or xenograft material from a lens capsule, wherein the process comprises the following steps:
Decellularizing (200) a lens capsule to obtain a decellularized lens capsule,
Depositing (300) the decellularized capsule on a microporous support membrane to obtain a stack composed of the decellularized lens capsule and the support membrane,
Lyophilizing (400) the stack to obtain a lyophilized stack,
Sterilizing (500) the lyophilized stack to obtain a sterilized stack,
Packaging (600) the sterilized stack to obtain allograft or xenograft materials.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Perrin, Rémi
Bindschedler, Pierre Etienne
Robach, Christine
Loup, Frédéric
Olard, François
Gallu, Raïssa
Dalmas, Florent
Gerard, Jean-François
Mechin, Françoise
Abrégé
The present invention relates to a polyurethane thermoplastic elastomer, to a composition comprising said polyurethane and a binder, for example bitumen and/or a biobased binder, and also to the use of the composition for the preparation of a waterproofing membrane, a soundproofing membrane, a liquid sealing system, a bituminous mix surfacing, a mastic asphalt surfacing, a primer, a varnish, a mastic, an adhesive or a binder emulsion
C08L 75/06 - Polyuréthanes à partir des polyesters
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD – LYON1 (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
INSA LYON (France)
Inventeur(s)
Sutter, Marc
Le Clerc, Christophe
Poloni, Mélissa
Colella, Marion
Fenouillot-Rimlinger, Françoise
Bernard, Julien
Abrégé
The invention relates to a polyester comprising ethylene 2,5-furandicarboxylate units and diethylene glycol units, said polyester having a melting temperature Tm of greater than or equal to 225°C and an intrinsic viscosity of greater than or equal to 0.65 dL/g, and in which the content of diethylene glycol (DEG) units is less than 4 mol% and the amount of ester functions located at the chain end is less than 100 meq/kg, and also to a method for producing polyester.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Bodennec, Jacques
Belmeguenaï, Amor
Bodennec, Selena
Bezin, Laurent
Georges, Béatrice
Blot, Victor
Abrégé
The present invention relates to structured molecular vectors of formula (I), compounds of formula (II) and pharmaceutical compositions comprising such compounds. The invention also relates to such pharmaceutical compositions for use for preventing and/or treating a disease chosen among an inflammatory disease or a disease associated with a cognitive disorder. The invention further relates to such pharmaceutical compositions for use for preventing cognitive decline or restoring cognitive functions altered in brain injuries and/or in traumatic brain injuries and/or in a neuroinflammatory disease, and/or in a neurodegenerative disease.
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
LA TANNERIE VEGETALE (France)
Inventeur(s)
Deleage, Fanny
Chalamet, Yvan
Abrégé
The present disclosure relates to a method for the preparation, from a mixture comprising (i) plant proteins, (ii) one or more plant tanning agents, (iii) one or more plasticizers, of a biobased material that may resemble animal leather.
C08L 89/00 - Compositions contenant des protéinesCompositions contenant leurs dérivés
D06N 3/12 - Cuir artificiel, toile cirée ou matériau similaire obtenu par enduction de nappes fibreuses avec une substance macromoléculaire, p. ex. avec des résines, du caoutchouc ou leurs dérivés avec des composés macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
C08J 3/20 - Formation de mélanges de polymères avec des additifs, p. ex. coloration
C08J 3/18 - Plastification de composés macromoléculaires
C08J 3/24 - Réticulation, p. ex. vulcanisation, de macromolécules
66.
Optical focusing system of an apparatus for cutting-out a human or animal tissue
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITÉ JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Romano, Fabrizio
Bernard, Aurelien
Mauclair, Cyril
Baubeau, Emmanuel
Abrégé
The present invention relates to apparatus for cutting out a human or animal tissue, such as a cornea, or a lens, said apparatus including a treatment device for producing a pattern consisting of at least two impact points in a focusing plane from a L.A.S.E.R. beam generated by a femtosecond laser (1), the treatment device being positioned downstream from said femtosecond laser, remarkable in that the treatment device comprises an optical focusing system (5) for focusing the L.A.S.E.R. beam in a cutting-out plane, and a control unit (6) able to control the displacement of the optical focusing system along an optical path of the L.A.S.E.R. beam for displacing the focusing plane in at least three respective cutting-out planes so as to form a stack of surfaces for cutting out the tissue.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
HOSPICES CIVILS DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (France)
Inventeur(s)
Do, Le Duy
Honnorat, Jerome
Pinto, Anne-Laurie
Moritz, Christian Peter
Antoine, Jean-Christophe
Camdessanche, Jean-Philippe
Muniz-Castrillo, Sergio
Abrégé
The invention relates to a process for identifying patients affected by an autoimmune neurological disease, comprising a step of detection of at least one type of anti-Argonaute autoantibodies (AGO-Abs) in a biological sample of an individual susceptible to be affected by said disease, wherein positive detection of said at least one type of AGO-Abs means that said individual is affected by said autoimmune neurological disease.
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
68.
ANTI-ARGONAUTE PROTEIN AUTOANTIBODIES AS BIOMARKERS OF AUTOIMMUNE NEUROLOGICAL DISEASES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
HOSPICES CIVILS DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
Inventeur(s)
Do, Le Duy
Honnorat, Jérôme
Pinto, Anne-Laurie
Moritz, Christian, Peter
Antoine, Jean-Christophe
Camdessanche, Jean-Philippe
Muniz-Castrillo, Sergio
Abrégé
The invention relates to a process for identifying patients affected by an autoimmune neurological disease, comprising a step of detection of at least one type of anti-Argonaute autoantibodies (AGO-Abs) in a biological sample of an individual susceptible to be affected by said disease, wherein positive detection of said at least one type of AGO-Abs means that said individual is affected by said autoimmune neurological disease.
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
69.
SEPARATOR FOR BATTERY COMPRISING A POROUS MEMBRANE FUNCTIONALISED BY A COPOLYMER COMPRISING A CROSS-LINKED UNIT AND A UNIT COMPRISING AN ALKALINE OR ALKALINE EARTH CATION AND CORRESPONDING BATTERY
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITÉ JEAN MONNET SAINT ETIENNE (France)
UNIVERSITE GRENOBLE ALPES (France)
UNIVERSITÉ SAVOIE MONT BLANC (France)
INSTITUT POLYTECHNIQUE DE GRENOBLE (France)
Inventeur(s)
Drockenmuller, Eric
Bouchet, Renaud
Flachard, Dimitri
Abrégé
A separator for a battery comprising a porous membrane functionalised by at least one copolymer comprising at least the following pendant units: - a unit comprising a cross-linked pendant group; - a unit comprising an anionic pendant group associated with a proton or a cation of an element selected from the group consisting of alkaline and alkaline earth metals, - optionally, a unit comprising a group selected from the group consisting of nitriles. The invention also relates to a method for preparing the separator and a battery comprising the separator having good performance in terms of power, energy density and cyclability, the separator preferably comprises an electrolyte block containing only salts provided by the battery.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 50/403 - Procédés de fabrication des séparateurs, des membranes ou des diaphragmes
VETAGRO-SUP INSTITUT D'ENSEIGNEMENT SUPÉRIEUR ET DE RECHERCHE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (France)
Inventeur(s)
David, Laurent
Montembault, Alexandra
Sudre, Guillaume
Nunes De Oliveira, Paula
Carozzo, Claude
Lux, François
Tillement, Olivier
Udrescu, Corina
Chapet, Olivier
Louis, Cédric
Abrégé
The invention relates to an imageable and resorbable medical device comprising at least one tubular portion (1) formed of a physical hydrogel of polysaccharides, capable of being inserted into the urethra of a subject, for various medical and/or surgical applications.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Heau, Christophe
Maurin-Perrier, Philippe
Garrelie, Florence
Colombier, Jean-Philippe
Pigeon, Florent
Abrégé
Disclosed is a machine (1) for treating parts (2) of different shapes, comprising an enclosure (10); a system for generating a vacuum (20); treatment systems (30, 60; 40, 60; 30, 40, 60), including a plasma generating system (30) and/or a vacuum deposition system (40); and a transportation system (50) suitable for moving the part or parts (2) in the enclosure (10), regardless of the shape of these parts (2); characterised in that the treatment systems (30, 60; 40, 60; 30, 40, 60) include a laser system (60) designed to treat the part or parts (2) arranged in the enclosure (10).
B01J 19/08 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage
B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage utilisant des radiations électromagnétiques
72.
MACHINE AND METHOD FOR TREATING PARTS OF DIFFERENT SHAPES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Héau, Christophe
Maurin-Perrier, Philippe
Garrelie, Florence
Colombier, Jean-Philippe
Pigeon, Florent
Abrégé
Disclosed is a machine (1) for treating parts (2) of different shapes, comprising an enclosure (10); a system for generating a vacuum (20); treatment systems (30, 60; 40, 60; 30, 40, 60), including a plasma generating system (30) and/or a vacuum deposition system (40); and a transportation system (50) suitable for moving the part or parts (2) in the enclosure (10), regardless of the shape of these parts (2); characterised in that the treatment systems (30, 60; 40, 60; 30, 40, 60) include a laser system (60) designed to treat the part or parts (2) arranged in the enclosure (10).
B01J 19/08 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage
B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage utilisant des radiations électromagnétiques
73.
SYSTEM FOR DETERMINING AN ARTERIAL PULSE WAVE VELOCITY
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
UNIVERSITÉ JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Lantelme, Pierre
Cividjian, Andrei
Harbaoui, Brahim
Abrégé
A system for determining a pulse velocity wave comprises an interface for receiving a signal indicating the proximal blood pressure in an artery and for receiving a signal indicating distal blood pressure in the artery. A processing device is configured to determine a proximal rising edge between a diastolic pressure and the systolic pressure of the proximal signal; determine a proximal pressure peak prior to the proximal rising edge; determine a distal rising edge between a diastolic pressure and a systolic pressure of the distal signal; determine a distal pressure peak prior to the distal rising edge and to determine whether the distal pressure peak is in phase advance with respect to the proximal pressure peak; and determine a propagation velocity of a regressive pulse wave depending on the phase advance of the distal pressure peak.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Faure, Nicolas
Pinston, Frédéric
Fournier, Corinne
Denis, Loïc
Olivier, Thomas
Abrégé
The invention relates to a focusing method for acquiring an image of a surface of interest (6) of a sample (1) by a holographic imager (2), comprising the following steps: - positioning the sample (1) comprising at least one reference object having a shape that is known and described by characterising parameters comprising at least position parameters; - acquiring an image and determining the position of the reference object relative to the acquisition plane (2') by applying a light diffraction model involving the spatial parameters of the reference object estimated by approximating the appearance of the reference object in the acquired holographic image; - determining the position of the surface of interest relative to the acquisition plane from a position of the reference object and focusing the image acquisition.
G03H 1/04 - Procédés ou appareils pour produire des hologrammes
G03H 1/00 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une imageLeurs détails spécifiques
G03H 1/08 - Procédés ou appareils pour produire des hologrammes pour faire des hologrammes synthétiques
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
UNIVERSITE JEAN MONNET SAINT-ETIENNE (France)
Inventeur(s)
Perie, Thomas
Lintingre, Eric
Auscher, Marie Camille
Buniazet, Zoé
Delaroa, Claire
Cassagnau, Philippe
Fulchiron, René
Abrégé
Disclosed is a binder for an injection moulding composition, the binder consisting of, in percentage by mass and for a total of 100%: 35% to 60% of a component (a), or "polymer base", consisting of a polymer or a mixture of polymers, each of said polymer being"non-amphiphilic" and having a mass average molar mass greater than or equal to 5000 g/mol, 30% to 55% of a component (b), or "wax", consisting of a polymer or a mixture of polymers, each of said polymers being non-amphiphilic and having a mass average molar mass less than 5000 g/mol, and less than 10% of an amphiphilic component (c), or "surfactant", and less than 10% of other components (d), the polymer base comprising 2% to 15% of a styrene-ethylene-butylene-styrene copolymer, or "SEBS", in percentage by mass based on the mass of the binder, the content by mass of styrene in the SEBS being greater than 15%, in percentage by mass based on the mass of the SEBS, the mass average molar mass of the SEBS being greater than 100,000 g/mol.
B22F 1/00 - Poudres métalliquesTraitement des poudres métalliques, p. ex. en vue de faciliter leur mise en œuvre ou d'améliorer leurs propriétés
B22F 3/00 - Fabrication de pièces ou d'objets à partir de poudres métalliques, caractérisée par le mode de compactage ou de frittageAppareils spécialement adaptés à cet effet
B29C 45/00 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet
The present invention relates to a method for detecting inflammation-related platelet activation, comprising measuring the quantity, concentration and/or proportion of seven specific biomarkers representative of 47 intra-platelet, soluble and membrane molecules, in a biological sample. Said panel of seven biomarkers is particularly useful for implementing a method for diagnosing inflammation-related platelet activation in an individual, a method for monitoring the effectiveness of a curative or preventive treatment of an inflammatory disease in an individual and/or a method for monitoring the development of an inflammatory disease associated with inflammation-related platelet activation in an individual. The present invention also relates to a kit for detecting inflammation-related platelet activation, as well as the use thereof.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
Institut National des Sciences Appliquees de Lyon (France)
Universite Claude Bernard Lyon I (France)
Centre National de la Recherche Scientifique - CNRS (France)
Universite Jean Monnet Saint Etienne (France)
Inventeur(s)
Ganachaud, Francois
Fleury, Etienne
Larribe, Gabriel
Mariot, David
Marchal, Frederic
Abrégé
A method for producing a porous silicone material including the following steps:
1) implementing a direct emulsion E of silicone in water including:
A) a silicone base A crosslinkable by polyaddition or polycondensation;
B) at least one nonionic silicone surfactant B having a cloud point between 10 and 50° C.;
C) optionally, at least one catalyst C; and
D) water;
2) heating the emulsion E to a temperature greater than or equal to 60° C. to obtain a porous silicone material; and
3) optionally, drying the porous silicone material.
C08J 9/28 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement par élimination d'une phase liquide d'un objet ou d'une composition macromoléculaire, p. ex. par séchage du coagulum
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Thevenet, Marc
Viret, Patricia
Abrégé
The invention relates to a device for olfactory stimulation of a patient with a plurality of scents, said device comprising: —a source (2) of a carrier gas (G); —a plurality of scent odorization circuits, each odorization circuit (4) comprising: —a container (18) containing an odorous volatile substance (V), —a container inlet line (26), provided with a container inlet valve (28), connecting an inlet (30) of said container with said source of carrier gas, and —a container outlet line (36), provided with a container outlet valve (38), connecting an outlet (40) of said container with an exit line (12); —a control unit (8), configured to control said container inlet valve and container outlet valve according to a medical protocol.
A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose
79.
EMULSION USABLE IN PARTICULAR AS A TECHNOLOGICAL AUXILIARY IN THE FIELD OF PLASTICS, OR AS AN ENCAPSULATION SYSTEM FOR ACTIVE AGENTS, PREPARATION METHOD AND APPLICATIONS THEREOF
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (France)
Inventeur(s)
Fouilloux, Alessandro
Jegat, Corinne
Abrégé
The invention relates to the field of emulsions which can be used as a technological auxiliary in particular in the field of plastics or as an encapsulation system for active agents. The present invention in particular relates to an emulsion comprising a polyol, a monounsaturated fatty acid and a milk protein.
A61J 3/00 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61K 47/12 - Acides carboxyliquesLeurs sels ou anhydrides
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
B01J 2/00 - Procédés ou dispositifs pour la granulation de substances, en généralTraitement de matériaux particulaires leur permettant de s'écouler librement, en général, p. ex. en les rendant hydrophobes
B01J 2/20 - Procédés ou dispositifs pour la granulation de substances, en généralTraitement de matériaux particulaires leur permettant de s'écouler librement, en général, p. ex. en les rendant hydrophobes en exprimant une substance à travers un crible et fragmentation de l'extrudat
B01J 13/00 - Chimie des colloïdes, p. ex. production de substances colloïdales ou de leurs solutions, non prévue ailleursFabrication de microcapsules ou de microbilles
B29B 9/06 - Fabrication de granulés par division de matière préformée sous forme de filaments, p. ex. combinée avec l'extrusion
B29B 9/12 - Fabrication de granulés caractérisés par la structure ou la composition
C08J 3/21 - Formation de mélanges de polymères avec des additifs, p. ex. coloration en présence d'une phase liquide le polymère étant prémélangé avec une phase liquide
B23K 26/00 - Travail par rayon laser, p. ex. soudage, découpage ou perçage
B23K 26/0622 - Mise en forme du faisceau laser, p. ex. à l’aide de masques ou de foyers multiples par commande directe du faisceau laser par impulsions de mise en forme
B23K 26/08 - Dispositifs comportant un mouvement relatif entre le faisceau laser et la pièce
B23K 26/352 - Travail par rayon laser, p. ex. soudage, découpage ou perçage pour le traitement de surface
B23K 103/00 - Matières à braser, souder ou découper
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Kämpfe, Thomas
Dubost, Laurent
Sedao, Xxx
Abrégé
The present invention relates to an optical device (1) suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum, said device (1) comprising at least: a substrate (10) made of a first material, a coating layer (20) made of a second material that is different from the first, and surface texturing (30) forming cavities (31) in the device (1), characterised in that the cavities (31) extend through the coating layer (20) and are partially sunk into the substrate (10).
G02B 1/12 - Revêtements optiques obtenus par application sur les éléments optiques ou par traitement de la surface de ceux-ci par traitement de la surface, p. ex. par irradiation
G02B 1/118 - Revêtements antiréfléchissants ayant des structures de surface de longueur d’onde sous-optique conçues pour améliorer la transmission, p. ex. structures du type œil de mite
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Kämpfe, Thomas
Dubost, Laurent
Sedao, Xxx
Abrégé
The present invention relates to an optical device (1) suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum, said device (1) comprising at least: a first coating layer (10) made of a first material, a substrate (50) made of a material that is different from the first material, and surface texturing (60) forming cavities (61) in the device (1); wherein a lower layer (50) disposed directly below the first coating layer (10) is either a second coating layer (20) made of a material that is different from the first material, or the substrate (50); wherein the lower layer (50) has a determined thickness (E50); characterised in that the cavities (61) extend through the coating layer (20) and are sunk into the lower layer (50) through at least part of the thickness (E50).
G02B 1/12 - Revêtements optiques obtenus par application sur les éléments optiques ou par traitement de la surface de ceux-ci par traitement de la surface, p. ex. par irradiation
G02B 1/118 - Revêtements antiréfléchissants ayant des structures de surface de longueur d’onde sous-optique conçues pour améliorer la transmission, p. ex. structures du type œil de mite
83.
METHOD FOR PREPARING AN EPOXIDISED DIENE ELASTOMER
COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
UNIVERSITE JEAN MONNET SAINT-ETIENNE (France)
Inventeur(s)
Roos, Kevin
Maximiano-Raimundo, Pedro
Bounor-Legare, Véronique
Ylla, Noellie
Beyou, Emmanuel
Cassagnau, Philippe
Abrégé
The invention relates to a method for bulk preparation of an epoxidised diene polymer in a tool for processing rubber, which method comprises at least two separate additions of a solid epoxidation agent. The method of the invention makes it possible to achieve an epoxidation rate that is comparable to the epoxidation rates achieved in a method where the diene polymer is epoxidised in solution, with a yield greater than or equal to 85%.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
CENTRE HOSPITALIER UNIVERSITAIRE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Gain, Philippe
Thuret, Gilles
Courrier, Emilie
Verhoeven, Paul
Ulrich, Gilles
Moine, Baptiste
Muzuzu, Wenziz
Sutter, Alexandra
De Nicola, Antoinette
Abrégé
The invention relates to a new fluorescent analogue of vancomycin and to the use of same to detect gram+ bacteria, in particular in a rapid diagnostic method for identifying the presence of gram+ bacteria in vivo, for example infectious keratitis, or in vitro on fluids or tissues taken from a human or animal subject.
G01N 33/94 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des narcotiques
C09B 23/04 - Colorants méthiniques ou polyméthiniques, p. ex. du type cyanine caractérisés par la chaîne méthinique contenant un nombre impair de groupes CH un seul groupe CH, p. ex. cyanines, isocyanines, pseudocyanines
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES LYON (France)
UNIVERSITÉ CLAUDE BERNARD LYON 1 (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Ganachaud, François
Portinha De Almeida, Daniel
Fleury, Etienne
Duaux, Gabriel
Genest, Aymeric
Pouget, Emmanuel
Abrégé
Silicone material obtained by a reaction between:—at least one organopolysiloxane (A) that has a molar mass of less than 70,000 g/mol, preferably less than 50,000 g/mol, and contains siloxyl units I.1 and I.2; and—at least one organic compound (B) carrying at least two carboxylic acid groups and having no unsaturation.
)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITÉ JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Vangheluwe, Marie
Vermeulin, Alice
Destouches, Nathalie
Hébert, Mathieu
Abrégé
A method for building a security image for a security structure of a security document from multiplexing color images, including selecting a marking method capable of producing sets of colors on the security document comprising different colors that can be displayed according to illumination/observation modes of the security structure, establishing a plurality of color sets that can be displayed by the security structure in a plurality of the different illumination/observation modes, distributing the color sets in a plurality of groups of color sets, establishing combinations of groups of color sets having at least one color set in common across the number of different illumination/observation modes, selecting a combination of a group of color sets based on the number of desired illumination/observation modes and the number of colors per color image, and determining the color images to multiplex by means of the combination of the group of color sets selected.
G06K 15/02 - Dispositions pour produire une présentation visuelle permanente des données de sortie utilisant des imprimantes
G06K 15/12 - Dispositions pour produire une présentation visuelle permanente des données de sortie utilisant des imprimantes par impression photographique
87.
Simulation of the deployment of an endoprosthesis in real time
ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DE METHODES ET PROCESSUS INDUSTRIELS—ARMINES (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CENTRE HOSPITALIER UNIVERSITAIRE SAINT-ETIENNE (France)
Inventeur(s)
Pionteck, Aymeric
Pierrat, Baptiste
Gorges, Sébastien
Albertini, Jean-Noël
Avril, Stéphane
Abrégé
A device for medical imaging by X-ray is provided. More specifically, it relates to the simulation of the deployment of an endoprosthesis in order to assist the surgeon in an endovascular surgical procedure. The invention makes use of a single 2D image in order to determine certain characteristics of a simplified model of the endoprosthesis: 2D positions, and deployment value of the stents; to determine the inherent rotation of at least one stent; then to determine the deployment of a model representing the structure of the stents, initialized on the basis of the preceding steps, in a 3D model of a vascular structure.
G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
88.
METHOD FOR PREPARING AN ALLOGRAFT OR XENOGRAFT MATERIAL FROM A CRYSTALLINE LENS CAPSULE
The present invention relates to a method for preparing an allograft or xenograft material from a crystalline lens capsule, notable in that the method comprises the following steps: - Removal of the cells (200) from a crystalline lens capsule (71) in order to obtain a cell-removed crystalline lens capsule, - Deposition of the cell-removed capsule on a microporous support membrane (31) in order to obtain a stack composed of the cell-removed crystalline lens capsule and the support membrane, - Freeze-drying (400) of the stack in order to obtain a freeze-dried stack, - Sterilisation (500) of the freeze-dried stack in order to obtain a sterilised stack, - Packaging (600) of the sterilised stack in order to obtain allograft or xenograft materials.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A23L 5/44 - Adjonction de colorants ou de pigments, p. ex. en combinaison avec des azurants optiques en utilisant des colorants ou des pigments organiques d'origine naturelle, leurs doublons artificiels ou leurs dérivés en utilisant des caroténoïdes ou des xanthophylles
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
CENTRE HOSPITALIER UNIVERSITAIRE (France)
Inventeur(s)
Gain, Philippe
Thuret, Gilles
Mauclair, Cyril
Albourgol, Samy
Egaud, Grégory
Abrégé
The present invention relates to a method for cutting up a previously removed corneal tissue in order to produce a plurality of implantable grafts, notable in that the method comprises the following steps: - Depositing (200) the corneal tissue in a device for holding the corneal tissue, - Cutting up (300), using a L.A.S.E.R source, the corneal tissue contained in the holding device in order to obtain a cut corneal tissue, - Detaching (400), manually or by means of an automated device, each graft of the cut corneal tissue, - Removing the cells (500), manually or by means of an automated device, from each detached graft in order to obtain cell-removed grafts, - Freeze-drying (600) each cell-removed graft in order to obtain freeze-dried grafts, - Sterilising (700) each freeze-dried graft in order to obtain sterilised grafts, - Packaging (800) each sterilised graft in order to obtain packaged grafts.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61F 2/14 - Parties d'yeux, p. ex. cristallins ou implants de cornéeYeux artificiels
90.
METHOD FOR MANUFACTURING AN OPTICAL MEASURING DEVICE CAPABLE OF OPERATING UNDER IONISING RADIATION AND OPTICAL MEASURING DEVICE CAPABLE OF OPERATING UNDER IONISING RADIATION
AGENCE NATIONALE POUR LA GESTION DES DECHETS RADIOACTIFS (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
OPTSYS (France)
Inventeur(s)
Girard, Sylvain
Allanche, Timothé
Boukenter, Aziz
Abrégé
The invention concerns a method for manufacturing an optical measuring device (1) capable of operating under ionising radiation. The method comprises, in particular: the selection of a pure silica glass as crown optical glass in order to form a first optical component (21); selecting a flint optical glass in a group of flint optical glasses each having a cerium-free composition, in order to form a second optical component (22); providing a detection system capable of operating under ionising radiation and associating the detection system and the first and second optical component (21, 22) in order to form the optical measuring device (1). The step of selecting the flint glass is carried out, in particular, from among glasses of the group of flint optical glasses on the basis of pre-irradiation and post irradiation transmission values.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Diefenbach, Dennis
Abrégé
The present invention is related to a method for processing a question in natural language received at a server (2), comprising performing by a processing unit (21) of the server (2) steps of: (a) for each n-gram of the question which is not a stop word, from at least one given knowledge base of entities linked by relations, identifying as initial entities and initial relations the entities and relations of the knowledge base matching said n-gram; (b) generating a set of possible queries for entities or relations of said given knowledge base, as a function of the initial entities and initial relations identified for all the n-gram of the question; (c) ranking each query of said set of possible queries as a function of at least one predetermined criterion, so as to identify a top-ranked possible query; (d) executing said top-ranked possible query, and returning the result entities or relations.
CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE (France)
BIOSPEEDIA (France)
Inventeur(s)
Pozzetto, Bruno
Begaud, Evelyne
Germani, Yves
Haddar, Cyrille
Carricajo, Anne
Abrégé
in vitroStreptococcus pneumoniaeStreptococcus pneumoniae), comprising at least two steps of detecting a pneumococcal antigen: (i) on a sample of secretions from the airways of a patient, and (ii) on the same sample after dilution.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
93.
POLYURETHANE THERMOPLASTIC ELASTOMER BASED ON HEXAMETHYLENE DIISOCYANATE
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Perrin, Remi
Bindschedler, Pierre Etienne
Robach, Christine
Loup, Frederic
Olard, Francois
Gallu, Raissa
Dalmas, Florent
Gerard, Jean-Francois
Mechin, Francoise
Pascault, Jean-Pierre (deceased)
Abrégé
The present invention relates to a polyurethane thermoplastic elastomer, to a composition comprising said polyurethane and a binder, for example bitumen and/or a biobased binder, and also to the use of the composition for the preparation of a waterproofing membrane, a soundproofing membrane, a liquid sealing system, a bituminous mix surfacing, a mastic asphalt surfacing, a primer, a varnish, a mastic, an adhesive or a binder emulsion
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Perrin, Rémi
Bindschedler, Pierre Etienne
Robach, Christine
Loup, Frédéric
Olard, François
Gallu, Raïssa
Dalmas, Florent
Gerard, Jean-François
Mechin, Françoise
Abrégé
The present invention relates to a polyurethane thermoplastic elastomer, to a composition comprising said polyurethane and a binder, for example bitumen and/or a biobased binder, and also to the use of the composition for the preparation of a waterproofing membrane, a soundproofing membrane, a liquid sealing system, a bituminous mix surfacing, a mastic asphalt surfacing, a primer, a varnish, a mastic, an adhesive or a binder emulsion
C08L 95/00 - Compositions contenant des matières bitumeuses, p. ex. asphalte, goudron ou brai
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Salemme, Romeo
Farne, Alessandro
Gaveau, Valérie
Belle, Anaël
Koun, Eric
Pavani, Francesco
Abrégé
This method for acquiring a spatial map of auditory perception of a subject comprises a plurality of successive test sequences, each test sequence comprising steps of: a) calibration (1002) of the subject's position, by displaying instructions to the subject, using a head-mounted visual display system worn by the subject, in order to acquire a reference position of the subject, the subject's position being measured using a video motion capture system by measuring the spatial coordinates of a first optical marker worn by the subject, b) choosing (1004) spatial coordinates of a target location of a sound source, said target cation being located around the subject, c) emitting (1006) a predefined sound, using a sound source placed at said target location, d) in response to acquisition instructions generated by the subject using an acquisition interface, acquiring (1008) an estimated location of said sound source, by using the video motion capture system to measure the spatial coordinates of a second optical marker held and pointed by the subject towards a perceived location of the sound source.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Bodennec, Jacques
Belmeguenaï, Amor
Bodennec, Selena
Bezin, Laurent
Georges, Béatrice
Blot, Victor
Abrégé
The present invention relates to structured molecular vectors of formula (I), compounds of formula (II) and pharmaceutical compositions comprising such compounds. The invention also relates to such pharmaceutical compositions for use for preventing and/or treating a disease chosen among an inflammatory disease or a disease associated with a cognitive disorder. The invention further relates to such pharmaceutical compositions for use for preventing cognitive decline or restoring cognitive functions altered in brain injuries and/or in traumatic brain injuries and/or in a neuroinflammatory disease, and/or in a neurodegenerative disease.
A61K 31/661 - Acides du phosphore ou leurs esters n'ayant pas de liaison P-C, p. ex. fosfosal, dichlorvos, malathion
A61K 31/662 - Acides du phosphore ou leurs esters ayant des liaisons P-C, p. ex. foscarnet, trichlorfon
A61K 31/685 - Diesters d'acide du phosphore avec deux composés hydroxyle, p. ex. phosphatidylinositols un des composés hydroxylés ayant des atomes d'azote, p. ex. phosphatidylsérine, lécithine
A61K 31/688 - Diesters d'acide du phosphore avec deux composés hydroxyle, p. ex. phosphatidylinositols les deux composés hydroxylés ayant des atomes d'azote, p. ex. sphingomyélines
A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61K 31/131 - Amines, p. ex. amantadine acycliques
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Bodennec, Jacques
Belmeguenai, Amor
Bodennec, Selena
Bezin, Laurent
Georges, Beatrice
Blot, Victor
Abrégé
The present invention relates to compounds of formula (IIA) represented by: R5-NH-CH2-CH(R7)-PO32' (IIA) wherein Rs and R7 are as defined herein and pharmaceutical compositions comprising such compounds. The invention also relates to such pharmaceutical compositions for use for preventing and/or treating a disease chosen among an inflammatory disease or a disease associated with a cognitive disorder. The invention further relates to such pharmaceutical compositions for use for preventing cognitive decline or restoring cognitive functions altered in brain injuries and/or in traumatic brain injuries and/or in a neuroinflammatory disease, and/or in a neurodegenerative disease.
A61K 31/662 - Acides du phosphore ou leurs esters ayant des liaisons P-C, p. ex. foscarnet, trichlorfon
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
98.
ELECTRICAL INSULATION MATERIAL AND MANUFACTURING PROCESS
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Lefort, Thibault
Bachellerie, Damien
Pruvost, Sébastien
Duchet, Jannick
Livi, Sébastien
Abrégé
The invention concerns an electrically insulating composite material (1) comprising a polyepoxide matrix (2) of cycloaliphatic or diglycidyl ether type in an amount of less than 40% by mass, from 20 to 75% by mass of one or more micrometric and/or mesometric fillers (3), and from 0.1 to 20% by mass of at least one ionic liquid (4), the masses being expressed relative to the total mass of the electrically insulating composite material (1). The invention also relates to a process for manufacturing such electrically insulating composite material (1), and also to the use thereof for an electrically insulating support (9) in a metal-enclosed substation (5).
C08K 5/5337 - Esters des acides phosphoniques contenant aussi des halogènes
C08L 65/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant une liaison carbone-carbone dans la chaîne principaleCompositions contenant des dérivés de tels polymères
H01B 3/40 - Isolateurs ou corps isolants caractérisés par le matériau isolantEmploi de matériaux spécifiés pour leurs propriétés isolantes ou diélectriques composés principalement de substances organiques matières plastiquesIsolateurs ou corps isolants caractérisés par le matériau isolantEmploi de matériaux spécifiés pour leurs propriétés isolantes ou diélectriques composés principalement de substances organiques résinesIsolateurs ou corps isolants caractérisés par le matériau isolantEmploi de matériaux spécifiés pour leurs propriétés isolantes ou diélectriques composés principalement de substances organiques cires résines époxy
H02K 3/30 - Enroulements caractérisés par leur matériau d'isolement
H02K 3/40 - Enroulements caractérisés par la configuration, la forme ou la réalisation de l'isolement pour hautes tensions, p. ex. assurant une protection contre les effluves
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE CENTRALE DE LYON (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE JEAN MONNET SAINT ETIENNE (France)
Inventeur(s)
Mouhaidali, Amjad
Tomeur-Dervout, Damien
Silvant, Sébastien
Abrégé
Method for modeling an electrical cable in order to use the electrical cable in a plurality of propagation modes associated with delays in the temporal domain, said method using a transfer matrix and comprising steps according to which a cable propagation mode is selected, an approximation is calculated of the transfer matrix in the form of a first rational function comprising approximation terms associated with each of the cable propagation modes which are different from the selected propagation mode, a residue matrix associated with the propagation mode is determined, an approximation of the residue matrix is calculated, said steps are repeated successively for each of the cable propagation modes, and an approximate transfer matrix is determined using the set of previously approximated residue matrices.
G01R 27/32 - Mesure de l'atténuation, du gain, du déphasage ou des caractéristiques qui en dérivent dans des réseaux électriques quadripoles, c.-à-d. des réseaux à double entréeMesure d'une réponse transitoire dans des circuits comportant des constantes réparties
100.
POLYMER COMPOSITES COMPRISING AN ALIPHATIC POLYAMIDE MATRIX AND SIZED GLASS OR BASALT FIBRES
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Orange, Gilles
Gabet, Yann
Espuche, Eliane
Gain, Olivier
Abrégé
Composite material comprising a) an aliphatic thermoplastic polyamide matrix polymer and b) glass or basalt fibres embedded in said matrix polymer a), wherein the glass or basalt fibres are coated with a sizing system comprising a polyamide-imide and/or a polyetherimide and, optionally, silica nanoparticles.
C08J 5/08 - Renforcement des composés macromoléculaires avec des matériaux fibreux en vrac ou en nappes utilisant des matériaux fibreux prétraités des fibres de verre
C03C 25/26 - Composés macromoléculaires ou prépolymères
C03C 25/42 - Revêtements contenant des substances inorganiques
C09D 179/08 - PolyimidesPolyesterimidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
C03C 25/1095 - Revêtement pour obtenir des tissus enduits
C03C 25/32 - Composés macromoléculaires ou prépolymères obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
C08K 9/08 - Ingrédients agglomérés par traitement avec un liant