A method for synthesizing a silicon and/or germanium nanowire(s) using a catalyst generated in situ is provided. The method provides high yield nanowire synthesis and comprises the steps of: combining a metal oxide, a reducing agent and a precursor in a reaction. The metal oxide and the reducing agent generate a metal oxide catalyst in situ in the reaction, and the catalyst reacts with the material from the precursor to synthesize nanowires.
C30B 7/14 - Croissance des monocristaux à partir de solutions en utilisant des solvants liquides à la température ordinaire, p. ex. à partir de solutions aqueuses le matériau à cristalliser étant produit dans la solution par des réactions chimiques
Disclosed is a transformer that includes a primary spiral inductor, and a secondary spiral inductor magnetically coupled to the primary spiral inductor, wherein a physical location of the secondary spiral inductor is at an offset relative to the primary spiral inductor to reduce interwinding capacitance between the primary and secondary spiral inductors, while decreasing a magnetic coupling between the primary and secondary spiral inductors to a lesser extent.
A method (100) of monitoring a flow of a powder (3) suspended in a fluid (7) through a section of pipe (5), the method (100) comprising: emitting a light signal (102) across the flow of powder (3); detecting the light signal (104) on an opposing side of the flow of powder (3), and generating an electrical signal (106) representative of the detected light signal as a function of time; dividing the electrical signal (108) into a plurality of windows (43); for at least some of the windows (43): converting the signal data to the frequency domain (110); determining one or more characteristics of the signal data (112) in the frequency domain; and determining flow properties of the powder (114) from the one or more characteristics of the signal data in the frequency domain.
An apparatus for the extracorporeal treatment of blood comprising an extracorporeal blood circuit (2), a pump (6) configured to provide fluid displacement within the extracorporeal blood circuit, and a reaction chamber (8) connected to the extracorporeal blood circuit and configured to receive blood or plasma from the circuit and treat the blood or plasma. The reaction chamber comprises a protease enzyme immobilized to a support, in which the protease enzyme is specific for, and capable of irreversibly cleaving, a human C5a present in the blood or plasma, wherein the abundance of the human C5a in the treated blood or plasma is less than that in the untreated blood or plasma. The apparatus finds utility in the extracorporeal treatment of blood from patients with inflammatory conditions, especially auto-immune disease and sepsis.
A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p. ex. adaptation de la température, irradiation
A61L 33/00 - Traitement antithrombogénique d'articles chirurgicaux, p. ex. de sutures, cathéters, prothèses ou d'articles pour la manipulation ou le conditionnement du sangMatériaux pour un tel traitement
A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c.-à-d. hémofiltration, diafiltration
A method of manufacturing a polymer film, the method comprising the steps of: (i) providing an aqueous electrolyte solution comprising water and a hydrophilic electrolyte; (ii) providing an organic electrolyte solution comprising an organic solvent and a lipophilic electrolyte; (iii) contacting the aqueous electrolyte solution with the organic electrolyte solution to form an interface between the aqueous electrolyte solution and the organic electrolyte solution; and (iv) electrochemically polarising the interface to oxidise the monomer, thereby forming a polymer film; wherein one of the aqueous electrolyte solution and the organic electrolyte solution comprises an oxidant; the other of the aqueous electrolyte solution and the organic electrolyte solution comprises a monomer; the aqueous electrolyte solution and the organic electrolyte solution are immiscible; and the concentration of the monomer is equal to or greater than the concentration of the oxidant.
C12Q 1/18 - Test de l'activité antimicrobienne d'un matériau
C12Q 1/37 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase faisant intervenir une peptidase ou une protéinase
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
A composite material for packaging applications. The composite material comprises lignin, a biodegradable thermoplastic polymer and a fibrous material and may provide a sustainable and readily biodegradable material to be used to form packaging with an improved environmental profile compared to known plastic packaging, without compromising on the performance of said packaging. A method of forming such a composite material and a use of a polymer blend comprising lignin and a biodegradable thermoplastic polymer to form a composite material with a fibrous material are also disclosed.
B32B 27/12 - Produits stratifiés composés essentiellement de résine synthétique adjacente à une couche fibreuse ou filamenteuse
B32B 5/02 - Produits stratifiés caractérisés par l'hétérogénéité ou la structure physique d'une des couches caractérisés par les caractéristiques de structure d'une couche comprenant des fibres ou des filaments
B32B 27/18 - Produits stratifiés composés essentiellement de résine synthétique caractérisée par l'emploi d'additifs particuliers
B32B 27/36 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyesters
B32B 37/18 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par les propriétés des couches toutes les couches existant et présentant une cohésion avant la stratification impliquant uniquement l'assemblage de feuilles ou de panneaux individualisés
A method of forming a carbon foam precursor for use in the formation of carbon foam materials. The carbon foam precursor comprises an aerogel of polymeric material which has a coating layer thereon, the coating layer comprising a material susceptible to dielectric heating, for example carbon nanotubes. The carbon foam precursor is suitable for forming into a carbon foam material using a dielectric heating step, despite the aerogel of polymeric material not being susceptible to dielectric heating, without adversely affecting the structure and physical properties of the carbon foam so formed. A carbon foam precursor, a carbon foam material and a method of forming such a carbon material are also disclosed.
C08J 3/24 - Réticulation, p. ex. vulcanisation, de macromolécules
C08J 9/28 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement par élimination d'une phase liquide d'un objet ou d'une composition macromoléculaire, p. ex. par séchage du coagulum
A method for producing silica, wherein the method comprises the steps of: providing a solution comprising: a silicate, and an organic polyamine or a salt thereof; and exposing the solution to carbon dioxide.
C01B 33/193 - Préparation de silice finement divisée ni sous forme de sol ni sous forme de gelPost-traitement de cette silice par traitement acide de silicates de solutions aqueuses de silicates
10.
GENE SIGNATURE FOR THE IDENTIFICATION OF LYMPH NODE INVOLVEMENT IN CANCER PATIENTS
A method for determining the presence or absence of lymph node metastasis in a breast cancer subject is provided. The method comprises the steps of assaying for expression of genes (or proteins encoded by the genes) ITGB4 and SNAI2 in a sample from the subject, wherein an increased expression of ITGB4 and a decreased expression of SNAI2 compared with the expression of the same genes (or proteins encoded by said genes) in a subject without cancer is indicative of the absence of lymph node metastasis in said subject. or wherein an increased expression of SNAI2 and a decreased expression of ITGB4 compared with the expression of the same genes (or proteins encoded by said genes) in a subject without cancer is indicative of the presence of lymph node metastasis in said subject.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
G16B 25/10 - Profilage de l’expression de gènes ou de protéinesEstimation ou normalisation de ratio d’expression
11.
IMPROVEMENTS IN AND RELATING TO MEASUREMENT OF SOLUTIONS USING NUCLEAR MAGNETIC RESONANCE
According to the present disclosure there is provided a method comprising providing a solution comprising a plurality of solution components; selecting a reference component from among the solution components; and using nuclear magnetic resonance, NMR, optionally low-field NMR, to measure a parameter of the reference component. The present disclosure also provides an apparatus comprising an NMR unit, optionally wherein the NMR unit is a low-field NMR unit, and a processor configured to perform the method.
G01N 24/08 - Recherche ou analyse des matériaux par l'utilisation de la résonance magnétique nucléaire, de la résonance paramagnétique électronique ou d'autres effets de spin en utilisant la résonance magnétique nucléaire
G01R 33/465 - Spectroscopie RMN appliquée à du matériau biologique, p. ex. tests in vitro
An electrode for an electrochemical sensor device. The electrode comprises a substrate, a carbon nanofibre layer and an enzyme immobilised on the carbon nanofibre layer. The carbon nanofibre layer comprises mesoporous carbon nanofibers and the enzyme is immobilised in the pores of the mesoporous carbon nanofibers. The carbon nanofibre layer is formed from lignin and a second polymeric material, wherein the second polymeric material is immiscible with lignin, through a process of stabilisation and carbonisation which provides a conductive carbon nanofibre framework comprising mesopores suitable for immobilisation of the enzyme. The enzyme immobilised in the carbon nanofibre layer can function by interacting with a target compound or biomarker in a sample solution applied to the electrode which produces a measurable electrochemical change in the electrode. A method of forming the electrode, a sensor device comprising the electrode, a use of a mesoporous carbon nanofibre material for immobilising an enzyme in a sensor device and a method of detecting a target compound or biomarker using the electrode are also disclosed. An electrode for an electrochemical sensor device. The electrode comprises a substrate, a carbon nanofibre layer and an enzyme immobilised on the carbon nanofibre layer. The carbon nanofibre layer comprises mesoporous carbon nanofibers and the enzyme is immobilised in the pores of the mesoporous carbon nanofibers. The carbon nanofibre layer is formed from lignin and a second polymeric material, wherein the second polymeric material is immiscible with lignin, through a process of stabilisation and carbonisation which provides a conductive carbon nanofibre framework comprising mesopores suitable for immobilisation of the enzyme. The enzyme immobilised in the carbon nanofibre layer can function by interacting with a target compound or biomarker in a sample solution applied to the electrode which produces a measurable electrochemical change in the electrode. A method of forming the electrode, a sensor device comprising the electrode, a use of a mesoporous carbon nanofibre material for immobilising an enzyme in a sensor device and a method of detecting a target compound or biomarker using the electrode are also disclosed.
C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions
C12N 11/02 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique
A monitoring system comprises sensors adapted to be worn by a user, and, a processor linked with the sensor. The processor receives sensor data and processes this data to determine user posture data including data indicative of vertical distance between level of the user's heart and ankle. Based on the posture data together with a value for degree of user chronic venous insufficiency and/or blood density, generate an estimate of user static venous pressure while the user is static, without calf muscle pump activity. The processor also processes the sensor data to determine if there is calf muscle pump activity, and generates an estimate of user active venous pressure according to the static venous pressure estimate, rate of calf muscle activity, and a value for degree of user chronic venous insufficiency. The processor may generate the venous pressure estimate in real time, and may control an NMES device accordingly.
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
A61B 5/0295 - Mesure du débit sanguin utilisant la pléthysmographie, c.-à-d. par mesure des variations du volume d'une partie du corps induites par la circulation du sang qui traverse cette partie, p. ex. pléthysmographie par impédance
A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A method for synthesizing an Si and/ or Ge NW/carbon composite in a solution-based approach is provided. The method comprises combining (i) a mixture of a lithium alloying metal and a carbon particle, (ii) an Si and/or Ge precursor and (iii) a refluxing solvent under reflux conditions and reacting to form the composites.
C01B 33/027 - Préparation par décomposition ou réduction de composés de silicium gazeux ou vaporisés autres que la silice ou un matériau contenant de la silice
C01B 33/03 - Préparation par décomposition ou réduction de composés de silicium gazeux ou vaporisés autres que la silice ou un matériau contenant de la silice par décomposition d'halogénures de silicium ou de silanes halogénés ou réduction de ceux-ci avec de l'hydrogène comme seul agent réducteur
H01G 11/24 - Électrodes caractérisées par les propriétés structurelles des matériaux composant les électrodes ou inclus dans les électrodes, p. ex. forme, surface ou porositéÉlectrodes caractérisées par les propriétés structurelles des poudres ou particules utilisées à cet effet
H01M 4/134 - Électrodes à base de métaux, de Si ou d'alliages
A securement device (1) for securely attaching tubular articles to surfaces comprising an anchor pad (3) for placing the securement device (1) on the surface, a substantially cylindrical base (4) on the anchor pad (3) and a screw cap (5) rotatably mountable on the base (4) at a screw mounting (6) defined between the base (4) and the screw cap (5) between an article receiving position and an article gripping position in which radial pressure is applied to the article placed in the securement device (1) to securely hold the article without the use of external adhesive fixings and prevent micro-pistoning of the article.
An apparatus for use in measuring a property of a fluid and a method of measuring a property of a fluid in a conduit. The apparatus is for use in measuring a property of a fluid, the apparatus comprising: a conduit comprising an inlet through which fluid can enter the conduit; a movable member retained within the conduit, the movable member configured to move in accordance with the property of the fluid in the conduit; and a magnetic field generating unit for generating one or more magnetic fields in the conduit, an interaction between the movable member and the one or more magnetic fields being detectable via the magnetic field generating unit, to measure the property.
G01F 1/24 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu en utilisant des effets mécaniques par détection des effets dynamiques de l’écoulement par débitmètres à section variable avec accouplement magnétique ou électrique au dispositif indicateur
G01F 1/58 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu en utilisant des effets électriques ou magnétiques par débitmètres électromagnétiques
There is provided a two part hardenable composition comprising a powder first part and a liquid second part. The parts are operable to form a glass ionomer cement which hardens to a solid mass upon mixing of the parts together. The composition comprises an inorganic glass and/or salt in the powder first part, an aqueous carrier in the liquid second part and an acid-functional polymer in the powder first part and/or the liquid second part. The composition also comprises an at least partially water-miscible additive in the first and/or second parts. The additive is operable to extend the working time of the glass ionomer cement upon mixing of the first and or second parts. The composition is operable to form a glass ionomer cement which, once hardened to a solid mass, has a plane strain fracture toughness of at least 0.7 MPa·m1/2 as measured at 24 hours from mixing. Also provided is a method of producing a glass ionomer cement.
C04B 28/28 - Compositions pour mortiers, béton ou pierre artificielle, contenant des liants inorganiques ou contenant le produit de réaction d'un liant inorganique et d'un liant organique, p. ex. contenant des ciments de polycarboxylates contenant des polyacides organiques, p. ex. contenant des ciments de polycarboxylates
The present invention relates to a diaphragm for a pressure sensor, the diaphragm comprising a hybrid sol-gel film. The invention also extends to a process for the manufacture of said diaphragm for a pressure sensor and to a pressure sensor comprising said diaphragm.
G01L 9/00 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pressionTransmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent
in situ in situ is provided. The method provides high yield nanowire synthesis and comprises the steps of: combining a metal oxide, a reducing agent and a precursor in a reaction. The metal oxide and the reducing agent generate a metal oxide catalyst in situ in the reaction, and the catalyst reacts with the material from the precursor to synthesize nanowires.
B01J 35/02 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général solides
C30B 29/60 - Monocristaux ou matériaux polycristallins homogènes de structure déterminée caractérisés par leurs matériaux ou par leur forme caractérisés par la forme
20.
HYBRID ULTRAMICROPOROUS MATERIALS FOR WATER CAPTURE AND RELEASE
A method of capturing water from a composition comprising water or water vapour using a hybrid ultramicroporous material. The method comprises the steps of: (a) providing a hybrid ultramicroporous material of formula [M(L)a(X)b]; and (b) contacting the hybrid ultramicroporous material with the composition comprising water to capture water into the hybrid ultramicroporous material; The hybrid ultramicroporous materials used in the method of the present invention have fast kinetics of water uptake and high working capacity compared to known commercial sorbent materials. The method of the present invention may be used in water capture and purification processes to provide fresh water suitable for drinking or for use in agriculture. The method of the present invention may also be used to remove water as a contaminant or for use in dehumidification processes. A use of such a hybrid ultramicroporous material and a device for capturing water are also disclosed.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
21.
Co-crystal compounds comprising lithium ions and isonicotinamide
Stable crystal forms comprising lithium ions and the conjugate base of an organic acid which is in the form of anhydrous coordination polymer that exhibit improved in vivo performance with respect to lithium carbonate.
C07F 1/00 - Composés contenant des éléments des groupes 1 ou 11 du tableau périodique
C07D 207/16 - Atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
A method for separating motile organisms from other organisms. The method comprises controlling a fluid delivery unit to provide a fluid flow to a sample separating device (302). The fluid flow has a sample introduction flow velocity set so that a sample may be introduced into a sample introduction zone of the device. The sample introduction flow velocity is sufficiently high such that an organism in the sample is unable to exit the sample introduction zone. The method comprises controlling the fluid delivery unit to reduce the fluid flow velocity from the sample introduction flow velocity to an operational flow velocity lower than the sample introduction flow velocity (303). The operational flow velocity is selected such that motile organisms in the sample are able to swim against the fluid flow and enter a sample collection zone of the device.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
The Board of Trustees of the Leland Stanford Junior University (USA)
University of Limerick (Irlande)
Inventeur(s)
Abel, Jonathan S.
Callery, Eoin F.
Abrégé
The present embodiments generally relate to enabling participants in an online gathering with networked audio to use a cancelling auralizer at their respective locations to create a common acoustic space or set of acoustic spaces shared among subgroups of participants. For example, there are a set of network connected nodes, and the nodes can contain speakers and microphones, as well as participants and node mixing-processing blocks. The node mixing-processing blocks generate and manipulate signals for playback over the node loudspeakers and for distribution to and from the network. This processing can include cancellation of loudspeaker signals from the microphone signals and auralization of signals according to control parameters that are developed locally and from the network. A network block can contain network routing and processing functions, including auralization, synthesis, and cancellation of audio signals, synthesis and processing of control parameters, and audio signal and control parameter routing.
A composite material for packaging applications. The composite material comprises lignin, a biodegradable thermoplastic polymer and a fibrous material and may provide a sustainable and readily biodegradable material to be used to form packaging with an improved environmental profile compared to known plastic packaging, without compromising on the performance of said packaging. A method of forming such a composite material and a use of a polymer blend comprising lignin and a biodegradable thermoplastic polymer to form a composite material with a fibrous material are also disclosed.
A method of producing a particle coating on one or more items is provided. The method comprises mixing supercritical carbon dioxide with a solution comprising dissolved material for forming particles. The method further comprises spraying the mixture into a precipitation chamber (316) to precipitate particles, wherein the chamber is at a pressure below a supercritical pressure of the supercritical fluid. The method also comprises capturing the precipitated particles on one or more items located within the chamber.
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61K 31/549 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. sulthiame ayant plusieurs atomes d'azote dans le même cycle, p. ex. hydrochlorothiazide
A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
B05D 1/12 - Application de matériaux en particules
A method of forming a carbon foam precursor for use in the formation of carbon foam materials. The carbon foam precursor comprises an aerogel of polymeric material which has a coating layer thereon, the coating layer comprising a material susceptible to dielectric heating, for example carbon nanotubes. The carbon foam precursor is suitable for forming into a carbon foam material using a dielectric heating step, despite the aerogel of polymeric material not being susceptible to dielectric heating, without adversely affecting the structure and physical properties of the carbon foam so formed. A carbon foam precursor, a carbon foam material and a method of forming such a carbon material are also disclosed.
C04B 38/00 - Mortiers, béton, pierre artificielle ou articles de céramiques poreuxLeur préparation
C04B 35/524 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base de non oxydes à base de carbone, p. ex. graphite obtenus à partir de précurseurs polymères, p. ex. carbone vitreux
C08J 9/00 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement
A method of producing a particle coating on one or more items is provided. The method comprises mixing a supercritical fluid with a solution comprising dissolved material for forming particles. The method further comprises spraying the mixture into a precipitation chamber (316) to precipitate particles, wherein the chamber is at a pressure below a supercritical pressure of the supercritical fluid. The method comprises conveying items to be coated from an inlet of the chamber to an outlet of the chamber. The method also comprises capturing the precipitated particles on items within the chamber.
B01J 2/00 - Procédés ou dispositifs pour la granulation de substances, en généralTraitement de matériaux particulaires leur permettant de s'écouler librement, en général, p. ex. en les rendant hydrophobes
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61K 31/549 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. sulthiame ayant plusieurs atomes d'azote dans le même cycle, p. ex. hydrochlorothiazide
A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A method of forming an electroconductive aerogel or hydrogel for use in tissue repair. The method comprises a) forming a suspension of nanoparticles of conductive polymeric material from a miniemulsion of monomeric material in an aqueous solvent; b) combining the suspension of nanoparticles of conductive polymeric material formed in step a) with a gel-forming component; c) forming the mixture obtained in step b) into a hydrogel and optionally step d) of lyophilising the hydrogel formed in step c) to produce the electroconductive aerogel. The method provides an electroconductive aerogel or hydrogel having advantageous conductivity whilst also having desirable mechanical properties approximate to native tissue which is to be repaired with the electroconductive aerogel or hydrogel. The present invention also provides electroconductive aerogels or hydrogels formed by this method and uses of said electroconductive aerogels or hydrogels for repairing tissue, for example in the treatment of spinal cord injury.
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
A method of manufacturing a polymer film, the method comprising the steps of: (i) providing an aqueous electrolyte solution comprising water and a hydrophilic electrolyte; (ii) providing an organic electrolyte solution comprising an organic solvent and a lipophilic electrolyte; (iii) contacting the aqueous electrolyte solution with the organic electrolyte solution to form an interface between the aqueous electrolyte solution and the organic electrolyte solution; and (iv) electrochemically polarising the interface to oxidise the monomer, thereby forming a polymer film; wherein one of the aqueous electrolyte solution and the organic electrolyte solution comprises an oxidant; the other of the aqueous electrolyte solution and the organic electrolyte solution comprises a monomer; the aqueous electrolyte solution and the organic electrolyte solution are immiscible; and the concentration of the monomer is equal to or greater than the concentration of the oxidant.
H01B 1/12 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement d'autres substances non métalliques substances organiques
C08L 81/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant uniquement du soufre, avec ou sans azote, oxygène ou carboneCompositions contenant des polysulfonesCompositions contenant des dérivés de tels polymères
The present invention relates to a method of modulating the permeability of an in vitro cellular barrier. The method comprises (i) culturing cells in culture media containing serum; and (ii) subsequently culturing said cells in culture media substantially free of serum. The invention also relates to an in vitro cellular barrier produced by the method and the use of an in vitro cellular barrier for assessing the permeation of a substance across said cellular barrier.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
Disclosed is a transformer that includes a primary spiral inductor, and a secondary spiral inductor magnetically coupled to the primary spiral inductor, wherein a physical location of the secondary spiral inductor is at an offset relative to the primary spiral inductor to reduce interwinding capacitance between the primary and secondary spiral inductors, while decreasing a magnetic coupling between the primary and secondary spiral inductors to a lesser extent.
H01F 17/00 - Inductances fixes du type pour signaux
H05K 1/16 - Circuits imprimés comprenant des composants électriques imprimés incorporés, p. ex. une résistance, un condensateur, une inductance imprimés
32.
GENE SIGNATURE FOR THE IDENTIFICATION OF LYMPH NODE INVOLVEMENT IN CANCER PATIENTS
A method for determining the presence or absence of lymph node metastasis in a breast cancer subject is provided. The method comprises the steps of assaying for expression of genes (or proteins encoded by the genes) ITGB4 and SNAI2 in a sample from the subject, wherein an increased expression of ITGB4 and a decreased expression of SNAI2 compared with the expression of the same genes (or proteins encoded by said genes) in a subject without cancer is indicative of the absence of lymph node metastasis in said subject, or wherein an increased expression of SNAI2 and a decreased expression of ITGB4 compared with the expression of the same genes (or proteins encoded by said genes) in a subject without cancer is indicative of the presence of lymph node metastasis in said subject.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
HH-pyrazolo[3,4-c]pyridine-3-carboxamide), B is a pharmaceutically acceptable carboxylic acid selected from fumaric acid or an aromatic carboxylic acid; and x is from 0.1 to 1.0.
C07C 65/21 - Composés comportant des groupes carboxyle liés à des atomes de carbone de cycles aromatiques à six chaînons et contenant l'un des groupes OH, O-métal, —CHO, cétone, éther, des groupes , des groupes ou des groupes contenant des groupes éther, des groupes , des groupes ou des groupes
C07C 229/60 - Composés contenant des groupes amino et carboxyle liés au même squelette carboné ayant des groupes amino et carboxyle liés à des atomes de carbone de cycles aromatiques à six chaînons du même squelette carboné avec des groupes amino et carboxyle liés à des atomes de carbone du même cycle aromatique à six chaînons non condensé avec des groupes amino et carboxyle liés en positions méta ou para
34.
Composite materials for damping acoustic vibrations
An article for damping vibrations by constrained layer damping comprising: a first constraining layer; a second constraining layer; and a damping layer disposed between the first and second constraining layers, wherein the first and second constraining layers each independently comprise a fibre-reinforced composite material, wherein the first and second constraining layers each independently have a thickness from 1.5 to 5 mm, wherein the damping layer comprises a viscoelastic material, wherein the damping layer has a thickness from 1 to 10 mm and wherein the article has a thickness from 6 to 50 mm. The invention also relates to the use of said article for damping vibrations in a vehicle.
B32B 27/18 - Produits stratifiés composés essentiellement de résine synthétique caractérisée par l'emploi d'additifs particuliers
B32B 25/08 - Produits stratifiés composés essentiellement de caoutchouc naturel ou synthétique comprenant du caoutchouc comme seul composant ou comme composant principal d'une couche adjacente à une autre couche d'une substance spécifique de résine synthétique
B32B 5/18 - Produits stratifiés caractérisés par l'hétérogénéité ou la structure physique d'une des couches caractérisés par le fait qu'une des couches contient un matériau sous forme de mousse ou essentiellement poreux
B32B 5/32 - Produits stratifiés caractérisés par l'hétérogénéité ou la structure physique d'une des couches caractérisés par la présence de plusieurs couches qui comportent des fibres, filaments, grains ou poudre, ou qui sont sous forme de mousse ou essentiellement poreuses les deux couches étant sous forme de mousse ou essentiellement poreuses
B32B 7/12 - Liaison entre couches utilisant des adhésifs interposés ou des matériaux interposés ayant des propriétés adhésives
B32B 25/14 - Produits stratifiés composés essentiellement de caoutchouc naturel ou synthétique comprenant des copolymères dans lesquels les composants en caoutchouc prédominent
B32B 27/30 - Produits stratifiés composés essentiellement de résine synthétique comprenant une résine vinyliqueProduits stratifiés composés essentiellement de résine synthétique comprenant une résine acrylique
B32B 27/38 - Produits stratifiés composés essentiellement de résine synthétique comprenant des résines époxy
B29C 70/44 - Façonnage ou imprégnation par compression pour la fabrication d'objets de longueur définie, c.-à-d. d'objets distincts utilisant une pression isostatique, p. ex. moulage par différence de pression, avec un sac à vide, dans un autoclave ou avec un caoutchouc expansible
An electrode for an electrochemical sensor device. The electrode comprises a substrate, a carbon nanofibre layer and an enzyme immobilised on the carbon nanofibre layer. The carbon nanofibre layer comprises mesoporous carbon nanofibers and the enzyme is immobilised in the pores of the mesoporous carbon nanofibers. The carbon nanofibre layer is formed from lignin and a second polymeric material, wherein the second polymeric material is immiscible with lignin, through a process of stabilisation and carbonisation which provides a conductive carbon nanofibre framework comprising mesopores suitable for immobilisation of the enzyme. The enzyme immobilised in the carbon nanofibre layer can function by interacting with a target compound or biomarker in a sample solution applied to the electrode which produces a measurable electrochemical change in the electrode. A method of forming the electrode, a sensor device comprising the electrode, a use of a mesoporous carbon nanofibre material for immobilising an enzyme in a sensor device and a method of detecting a target compound or biomarker using the electrode are also disclosed. An electrode for an electrochemical sensor device. The electrode comprises a substrate, a carbon nanofibre layer and an enzyme immobilised on the carbon nanofibre layer. The carbon nanofibre layer comprises mesoporous carbon nanofibers and the enzyme is immobilised in the pores of the mesoporous carbon nanofibers. The carbon nanofibre layer is formed from lignin and a second polymeric material, wherein the second polymeric material is immiscible with lignin, through a process of stabilisation and carbonisation which provides a conductive carbon nanofibre framework comprising mesopores suitable for immobilisation of the enzyme. The enzyme immobilised in the carbon nanofibre layer can function by interacting with a target compound or biomarker in a sample solution applied to the electrode which produces a measurable electrochemical change in the electrode. A method of forming the electrode, a sensor device comprising the electrode, a use of a mesoporous carbon nanofibre material for immobilising an enzyme in a sensor device and a method of detecting a target compound or biomarker using the electrode are also disclosed.
C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions
G01N 27/00 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques
C12N 11/04 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique piégées à l’intérieur du support, p. ex. dans un gel ou dans des fibres creuses
D01D 5/00 - Formation des filaments, fils ou similaires
A method of purifying gaseous mixtures, for example ternary or quaternary gaseous mixtures, using a sorbent media comprising two or more sorbent materials. The method involves obtaining a target gas from a gaseous composition comprising the target gas, a first gas and a second gas, and optionally further gases by contacting the gaseous composition with the sorbent media to remove at least some of the first gas and at least some of the second gas from the gaseous composition. The sorbent media comprises at least a first sorbent material and a second sorbent material; wherein the first sorbent material has a higher adsorption selectivity for the first gas than for the target gas; and wherein the second sorbent material has a higher adsorption selectivity for the second gas than for target gas. The method may be particularly useful for the separation of pure ethylene, methane or propylene from such gaseous mixtures. A sorbent media and an apparatus for obtaining a target gas from such a gaseous composition are also disclosed.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
C07C 7/12 - Purification, séparation ou stabilisation d'hydrocarburesEmploi d'additifs par adsorption, c.-à-d. purification ou séparation d'hydrocarbures à l'aide de solides, p. ex. à l'aide d'échangeurs d'ions
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
Deployable structures, methods and apparatus for deployment of deployable structures, and associated manufacturing methods. Such deployable structures suitably comprise components for space structures, such supports for solar arrays, antennas or other similar systems. The deployable structure comprises a lattice element arrangeable in a stowed configuration and a deployed configuration. The lattice element comprises a pre-stressed strip arranged in a clockwise helix, a pre-stressed strip arranged in an anticlockwise helix, and a plurality of fasteners for rotatably coupling the strips to one another at a plurality of positions distributed along the length of the strips. The fasteners are provided at unequal spacings along the length of the strips such that on deployment the lattice element bends to a curved deployed configuration.
The present disclosure relates to deployable structures, to methods and apparatus for deployment of deployable structures, and to associated manufacturing methods. Such deployable structures suitably comprise components for space structures, such supports for solar arrays, antennas or other similar systems. The deployable structure (500) comprises a first lattice (514) arrangeable in a stowed configuration and a deployed configuration. The deployable structure also comprises a second lattice (516) arrangeable in a stowed configuration and a deployed configuration, wherein with the lattices arranged in the stowed configuration the second lattice (516) nests in the first lattice (514).
The Applicant has discovered a cytokine profile that can accurately distinguish between ulcerative colitis (UC) and Crohn's disease (CD) in a subject having, or having symptoms of, inflammatory bowel disease (IBD). The profile of ulcerative colitis is increased IL-10 levels (compared with a reference IL-10 level, and decreased IL-23 levels (compared with a reference IL-23 level). The cytokine profile can be detected at a protein or genomic level, and is generally determined from a peripheral blood sample (i.e. a blood fraction such as serum, plasma, or blood cells such as peripheral blood mononuclear cells). Distinguishing between UC and CD in a subject with IBD allows a clinician prescribe a suitable therapeutic regime for the subject using a non-invasive blood test, and avoiding the need for scoping or tissue biopsy, which are undesirable for the subject. The cytokine profile can also be used to monitor a therapeutic regime for effectiveness.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
Carbon fibre precursors for use in the formation of carbon fibre materials. The carbon fibre precursors comprise fibres of polymeric material which have a coating layer thereon, the coating layer comprising a material susceptible to dielectric heating, for example carbon nanotubes. The carbon fibre precursors may be suitable for forming into carbon fibres using a dielectric heating step, despite the fibres of polymeric material not being susceptible to dielectric heating, without adversely affecting the structure and physical properties of the main body of the carbon fibre so formed. A method of preparing a carbon fibre precursor for a carbon fibre formation process and a method forming a carbon fibre are also disclosed.
A spreading apparatus for use with fibre-reinforced composite tapes, and related methods are disclosed. The spreading apparatus comprises an input side to receive an incoming tape to be spread, and an output side from which tape is delivered after spreading. The apparatus further comprises a tape heater (150, 250, 650) to in use apply heat to a tape; and a tape spreader (100, 1, 200, 600) to in use to apply contact pressure to the heated tape to thereby spread the tape.
An ostomy attachment comprises a flexible annular seal configured to embrace a stoma and a spout that in use is disposed beneath the stoma and configured to collect ostomy output at skin level and direct ostomy output away from the patient and annular seal and into an ostomy bag, in which the flexible annular seal is formed from an absorbent material and the spout is formed from a non-absorbent material. The annular seal may be an open ring comprising at least one mouldable arm that in use can be wrapped at least partially around the patients' stoma.
A61F 5/44 - Dispositifs portés par le patient pour recueillir l'urine, les selles, les menstrues ou d'autres sécrétionsDispositifs de colostomie
A61F 5/448 - Moyens d'assujettissement du sac à l'anneau d'étanchéité
A61F 5/443 - Dispositifs portés par le patient pour recueillir l'urine, les selles, les menstrues ou d'autres sécrétionsDispositifs de colostomie comportant des joints d'étanchéité de type hydrocolloïde, p. ex. gels, empois d'amidon, gomme Karaya
A multicomponent crystal (or co-crystal) comprising a first active pharmaceutical ingredient and a second active pharmaceutical ingredient. The multicomponent crystal is formed/sustained by non-covalent interactions between the nitrogen-containing heterocycle alpha-substituted with an amino group of the first active pharmaceutical ingredient and a carboxylic acid group of the second active pharmaceutical ingredient, suitably as well as other further non-covalent interactions with other H-bond forming groups. The multicomponent crystal may provide an improved multidrug dosage form comprising lamotrigine and valproic acid as the first and second active pharmaceutical ingredients, respectively. A pharmaceutical composition comprising a therapeutically effective amount of the multicomponent crystal and a pharmaceutically acceptable excipient, and a method of forming the multicomponent crystal, are also provided.
A61K 31/53 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec trois azote comme seuls hétéro-atomes d'un cycle, p. ex. chlorazanil, mélamine
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61K 31/431 - Composés contenant des systèmes cycliques thia-4 aza-1 bicyclo [3.2.0] heptane, c.-à-d. composés contenant un système cyclique de formule , p. ex. pénicillines, pénèmes contenant d'autres systèmes hétérocycliques, p. ex. ticarcilline, azlocilline, oxacilline
A61K 31/43 - Composés contenant des systèmes cycliques thia-4 aza-1 bicyclo [3.2.0] heptane, c.-à-d. composés contenant un système cyclique de formule , p. ex. pénicillines, pénèmes
A61K 31/545 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine
A61K 31/546 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine contenant d'autres hétérocycles, p. ex. céphalotine
A61K 31/606 - Acide salicyliqueSes dérivés ayant des groupes amino
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 31/4995 - Pyrazines ou pipérazines formant une partie de systèmes cycliques pontés
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A vibrational energy harvester (100, 200, 300, 400) comprises a first mass (101, 201, 301) comprising a first internal cavity (102, 202, 302) and a second mass (103, 203) disposed within and configured to move within the first internal cavity. Movement of the second mass relative to the first mass induces an electrical current in one of the first mass and the second mass. The vibrational energy harvester also comprises a housing (104, 204, 404) comprising a second internal cavity (105, 405). The first mass is disposed within and configured to move within the second internal cavity. An adjustment mechanism (419) is also provided, configured to adjust a size of the second internal cavity.
H02K 35/02 - Génératrices avec système de bobines, aimant, induit, ou autre partie du circuit magnétique à mouvement alternatif, oscillant ou vibrant avec des aimants mobiles et des systèmes de bobines fixes
The present invention relates to a diaphragm for a pressure sensor, the diaphragm comprising a hybrid sol-gel film. The invention also extends to a process for the manufacture of said diaphragm for a pressure sensor and to a pressure sensor comprising said diaphragm.
G01L 9/00 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pressionTransmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent
There is provided a two part hardenable composition comprising a powder first part and a liquid second part. The parts are operable to form a glass ionomer cement which hardens to a solid mass upon mixing of the parts together. The composition comprises an inorganic glass and/or salt in the powder first part, an aqueous carrier in the liquid second part and an acid-functional polymer in the powder first part and/or the liquid second part. The composition also comprises an at least partially water-miscible additive in the first and/or second parts. The additive is operable to extend the working time of the glass ionomer cement upon mixing of the first and or second parts. The composition is operable to form a glass ionomer cement which, once hardened to a solid mass, has a plane strain fracture toughness of at least 0.7 MPa.m1/2 as measured at 24 hours from mixing. Also provided is a method of producing a glass ionomer cement.
A61K 6/889 - Ciments à base de polycarboxylateCiments à base de verre ionomère
A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
C03C 4/00 - Compositions pour verres ayant des propriétés particulières
A thermoelectric material comprising carbon nanotubes and lignin. The carbon nanotubes are present as fibres and the lignin is present in pores and/or voids in the carbon nanotube fibres. The lignin may act as a dopant to increase the thermoelectric efficiency of the carbon nanotubes, multi-walled carbon nanotubes in particular. A method of forming a thermoelectric material involving impregnating fibres of carbon nanotubes with lignin, is also provided. A thermoelectric element, a fabric and a thermoelectric device comprising the thermoelectric material are also provided. The thermoelectric material may be particularly useful for the production of wearable thermoelectric devices.
According to the present invention there is provided a sample separating device for separating motile organisms from other organisms, the device comprising: one or more primary fluid paths extending between a fluid inlet and a fluid terminus such that a fluid flow may be established between the fluid inlet and the fluid terminus; a sample introduction zone in the primary fluid path for introducing a sample to the primary fluid path; a sample collection zone for collecting a collected sample therein, the sample collection zone being located at a location upstream of the sample introduction zone in the primary fluid path; a sample collection zone outlet for facilitating removal of the collected sample from the sample collection zone; the sample separating device being arranged to allow communication with a sample moving system for moving the collected sample through the sample collection zone, thereby to move at least some of the collected sample from the sample collection zone to the sample collection zone outlet.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
A method for separating motile organisms from other organisms. The method comprises controlling a fluid delivery unit to provide a fluid flow to a sample separating device (302). The fluid flow has a sample introduction flow velocity set so that a sample may be introduced into a sample introduction zone of the device. The sample introduction flow velocity is sufficiently high such that an organism in the sample is unable to exit the sample introduction zone. The method comprises controlling the fluid delivery unit to reduce the fluid flow velocity from the sample introduction flow velocity to an operational flow velocity lower than the sample introduction flow velocity (303). The operational flow velocity is selected such that motile organisms in the sample are able to swim against the fluid flow and enter a sample collection zone of the device.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
An isolated protease comprising a polypeptide having the structure is described: P-A-B5 in which P is a protease domain, A is an A-domain, and B is a B-domain, of a Group VII to XIII cell envelope protease (CEP), wherein the protease does not have a PA domain. An isolated protease according to Claim 1, selected from a wild-type Group VII to XIII cell envelope protease. The use of the protease as a medicament is treating immune dysregulation diseases is also described.
A securement device 1 for securely attaching tubular articles 2 to surfaces comprising an anchor pad 3 for placing the securement device 1 on the surface, a substantially cylindrical base 4 on the anchor pad 3 and a screw cap 5 rotatably mountable on the base 4 at a screw mounting 6 defined between the base 4 and the screw cap 5 between an article receiving position and an article gripping position in which radial pressure is applied to the article 2 placed in the securement device 1 to securely hold the article 2 without the use of external adhesive fixings and prevent micro-pistoning of the article 2.
WROCLAW UNIVERSITY OF SCIENCE AND TECHNOLOGY (Pologne)
Inventeur(s)
Mani, Alaa, Addin
Bauer, Joanna
O'Mahony, Charlie
Markham, Sarah, Kate
Tofail, Syed, A.M.
Silien, Christophe
Ul Haq, Ehstham
Abrégé
The invention discloses a method and system for detecting and locating a buried defect in a test object, comprises heating a surface of said test object by exposing said surface with one or more radiation sources for a first predetermined duration of time from a plurality of angles with respect to said surface of said object. After each exposure of said plurality of angles, recording a thermogram of said surface for a second predetermined duration using an infrared image capture device, wherein said infrared image capture device is static with reference to said test object; determining a time within said second predetermined time duration where a maximum variation of temperature occurs with respect to a reference thermogram; and extracting a thermal image of said surface from said thermogram at said time.
A method of capturing water from a composition comprising water or water vapour using a hybrid ultramicroporous material. The method comprises the steps of: (a) providing a hybrid ultramicroporous material of formula [M(L)a(X)b]; and (b) contacting the hybrid ultramicroporous material with the composition comprising water to capture water into the hybrid ultramicroporous material; The hybrid ultramicroporous materials used in the method of the present invention have fast kinetics of water uptake and high working capacity compared to known commercial sorbent materials. The method of the present invention may be used in water capture and purification processes to provide fresh water suitable for drinking or for use in agriculture. The method of the present invention may also be used to remove water as a contaminant or for use in dehumidification processes. A use of such a hybrid ultramicroporous material and a device for capturing water are also disclosed.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
B01D 53/04 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse avec adsorbants fixes
C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
A method of producing a particle coating on one or more items is provided. The method comprises mixing a supercritical fluid with a solution comprising dissolved material for forming particles. The method further comprises spraying the mixture into a precipitation chamber (316) to precipitate particles, wherein the chamber is at a pressure below a supercritical pressure of the supercritical fluid. The method comprises conveying items to be coated from an inlet of the chamber to an outlet of the chamber. The method also comprises capturing the precipitated particles on items within the chamber.
B01J 2/02 - Procédés ou dispositifs pour la granulation de substances, en généralTraitement de matériaux particulaires leur permettant de s'écouler librement, en général, p. ex. en les rendant hydrophobes par division du produit liquide en gouttelettes, p. ex. par pulvérisation, et solidification des gouttelettes
B01J 2/00 - Procédés ou dispositifs pour la granulation de substances, en généralTraitement de matériaux particulaires leur permettant de s'écouler librement, en général, p. ex. en les rendant hydrophobes
55.
APPARATUS FOR USE IN MEASURING A PROPERTY OF A FLUID AND METHOD
An apparatus for use in measuring a property of a fluid and a method of measuring a property of a fluid in a conduit. The apparatus is for use in measuring a property of a fluid, the apparatus comprising: a conduit comprising an inlet through which fluid can enter the conduit; a movable member retained within the conduit, the movable member configured to move in accordance with the property of the fluid in the conduit; and a magnetic field generating unit for generating one or more magnetic fields in the conduit, an interaction between the movable member and the one or more magnetic fields being detectable via the magnetic field generating unit, to measure the property.
G01F 1/58 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu en utilisant des effets électriques ou magnétiques par débitmètres électromagnétiques
G01F 1/24 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu en utilisant des effets mécaniques par détection des effets dynamiques de l’écoulement par débitmètres à section variable avec accouplement magnétique ou électrique au dispositif indicateur
A method of producing a particle coating on one or more items is provided. The method comprises mixing supercritical carbon dioxide with a solution comprising dissolved material for forming particles. The method further comprises spraying the mixture into a precipitation chamber (316) to precipitate particles, wherein the chamber is at a pressure below a supercritical pressure of the supercritical fluid. The method also comprises capturing the precipitated particles on one or more items located within the chamber.
A PCB, printed circuit board, structure for forming at least one embedded electronic component. The structure comprises a multi-layer PCB board comprising at least one through-hole via, the via comprising a plurality of electrodes vertically aligned within the via, each electrode comprising a plated ring; and an isolation section separating each of the electrodes.
H05K 3/04 - Élimination du matériau conducteur par voie mécanique, p. ex. par poinçonnage
H05K 1/11 - Éléments imprimés pour réaliser des connexions électriques avec ou entre des circuits imprimés
H05K 1/16 - Circuits imprimés comprenant des composants électriques imprimés incorporés, p. ex. une résistance, un condensateur, une inductance imprimés
H05K 3/00 - Appareils ou procédés pour la fabrication de circuits imprimés
A switched mode power supply converter comprises a circuit pulse matching circuit configured to negate output voltage disturbance or noise during switching operation of a power conversion. The current pulse matching circuit input is driven by, or from, a power converter switch node of the switched mode power supply converter. The current pulse matching circuit comprises a rate-of-voltage change detection circuit driven by the power converter switch node.
H02M 1/15 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu utilisant des éléments actifs
H02M 1/44 - Circuits ou dispositions pour corriger les interférences électromagnétiques dans les convertisseurs ou les onduleurs
H02M 3/157 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation avec commande numérique
H02M 1/14 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu
A pipe section (1) for carrying cohesive powders, the pipe section (1) formed of a boundary wall (3) defining a passage (5) and including a plurality of pipe portions (13, 15, 17, 19), the pipe portions (13, 15, 17, 19) comprising, in series: an inlet portion (13) in which the passage (5) substantially extends along a first axis (21); a corner portion (15) defining a bend (29) within which the passage (5) turns from extending along the first axis (21), to extending along a second axis (35) different to the first axis (21), the corner portion (15) defining an inner side (39) of the bend (29) and an opposing outer side (37) of the bend (29); a deflection portion (17) to disperse agglomerations (57) of powder (7) formed in the passage (5) at the corner portion (15) by directing agglomerated material (57) from the outer side (37) of the bend (29) towards the centre of the passage (5); and an outlet portion (19) substantially extending along the second axis (35).
A method, a false start detection system, and a false start detection sensor for determining whether an athlete has performed a false start in an event. Force data is received representing the force exerted by at least one upper appendage of the athlete on a surface when in a starting position (S701). The force data is processed to determine an athlete start time (S702), and the athlete start time is compared to an event start time to determine whether a false start has occurred (S703).
An article for damping vibrations by constrained layer damping comprising: a first constraining layer; a second constraining layer; and a damping layer disposed between the first and second constraining layers, wherein the first and second constraining layers each independently comprise a fibre-reinforced composite material, wherein the first and second constraining layers each independently have a thickness from 1.5 to 5 mm, wherein the damping layer comprises a viscoelastic material, wherein the damping layer has a thickness from 1 to 10 mm and wherein the article has a thickness from 6 to 50 mm. The invention also relates to the use of said article for damping vibrations in a vehicle.
B32B 25/10 - Produits stratifiés composés essentiellement de caoutchouc naturel ou synthétique adjacent à une couche fibreuse ou filamenteuse
B32B 27/12 - Produits stratifiés composés essentiellement de résine synthétique adjacente à une couche fibreuse ou filamenteuse
F16F 15/04 - Suppression des vibrations dans les systèmes non rotatifs, p. ex. dans des systèmes alternatifsSuppression des vibrations dans les systèmes rotatifs par l'utilisation d'organes ne se déplaçant pas avec le système rotatif utilisant des moyens élastiques
A method and apparatus for real-time in-mould marking of a moulded or cast form with an identifier in which a configurable marking module (1) with phase change actuators (23) in the form of a multi-layered printed circuit board assembly (1) with a vertical element (33) having a marker (21) is installed in a mould (2), (35), the marker (21) being remotely configurable by a controller to create a unique identifier which is applied to the form in the mould.
B22D 17/22 - Moules métalliquesPlaques de moulesSupports de moulesÉquipement de refroidissement des moulesAccessoires pour l'extraction et l'éjection des pièces hors du moule
B22C 23/00 - OutillageDispositifs de moulage non prévus ailleurs
B29C 33/42 - Moules ou noyauxLeurs détails ou accessoires caractérisés par la forme de la surface de moulage, p. ex. par des nervures ou des rainures
MONAGHAN MUSHROOMS IRELAND UNLIMITED COMPANY (Irlande)
UNIVERSITY OF LIMERICK (Irlande)
Inventeur(s)
Gaffney, Darragh
Dwyer, Kelly
Walsh, Gary
Winger, Alison
Abrégé
The present invention relates to an isolated polypeptide having xylanase activity. Also disclosed are isolated polynucleotides encoding the polypeptide, recombinant host cells expressing the polypeptide, and methods for degrading lignocellulosic biomass using the polypeptide. He invention finds utility in the production of biofuels, in the paper and pulp industry, in clothing or leather softening, in the food industry such as baking, etc.
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
A method of purifying gaseous mixtures, for example ternary or quaternary gaseous mixtures, using a sorbent media comprising two or more sorbent materials. The method involves obtaining a target gas from a gaseous composition comprising the target gas, a first gas and a second gas, and optionally further gases by contacting the gaseous composition with the sorbent media to remove at least some of the first gas and at least some of the second gas from the gaseous composition. The sorbent media comprises at least a first sorbent material and a second sorbent material; wherein the first sorbent material has a higher adsorption selectivity for the first gas than for the target gas; and wherein the second sorbent material has a higher adsorption selectivity for the second gas than for target gas. The method may be particularly useful for the separation of pure ethylene, methane or propylene from such gaseous mixtures. A sorbent media and an apparatus for obtaining a target gas from such a gaseous composition are also disclosed.
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
C07C 1/00 - Préparation d'hydrocarbures à partir d'un ou plusieurs composés, aucun d'eux n'étant un hydrocarbure
The present disclosure relates to deployable structures, to methods and apparatus for deployment of deployable structures, and to associated manufacturing methods. Such deployable structures suitably comprise components for space structures, such supports for solar arrays, antennas or other similar systems. The deployable structure comprises a lattice element arrangeable in a stowed configuration and a deployed configuration. The lattice element (200) comprises a pre-stressed strip arranged in a clockwise helix (306, Fig. 3a), a pre-stressed strip arranged in an anticlockwise helix (308, Fig. 3a), and a plurality of fasteners (310, Fig. 3a) for rotatably coupling the strips to one another at a plurality of positions distributed along the length of the strips. The fasteners are provided at unequal spacings along the length of the strips such that on deployment the lattice element bends to a curved deployed configuration.
The present disclosure relates to deployable structures, to methods and apparatus for deployment of deployable structures, and to associated manufacturing methods. Such deployable structures suitably comprise components for space structures, such supports for solar arrays, antennas or other similar systems. The deployable structure comprises a lattice element (202) and a deployment mechanism (204). The lattice element is arrangeable in a stowed configuration and a deployed configuration, wherein deployment from the stowed configuration to the deployed configuration takes place using the stored energy of bending in the lattice element (202). The deployment mechanism comprises a tension element to regulate deployment.
The present disclosure relates to deployable structures, to methods and apparatus for deployment of deployable structures, and to associated manufacturing methods. Such deployable structures suitably comprise components for space structures, such supports for solar arrays, antennas or other similar systems. The deployable structure (500) comprises a first lattice (514) arrangeable in a stowed configuration and a deployed configuration. The deployable structure also comprises a second lattice (516) arrangeable in a stowed configuration and a deployed configuration, wherein with the lattices arranged in the stowed configuration the second lattice (516) nests in the first lattice (514).
A method of processing an active pharmaceutical ingredient, the method comprising passing a precursor composition comprising the active pharmaceutical ingredient and a solvent through a twin screw extruder wherein the twin screw extruder is heated at ambient pressure.
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61J 3/02 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de poudres
69.
Networked audio auralization and feedback cancellation system and method
The Board of Trustees of the Leland Stanford Junior University (USA)
University of Limerick (Irlande)
Inventeur(s)
Abel, Jonathan S.
Callery, Eoin F.
Abrégé
The present embodiments generally relate to enabling participants in an online gathering with networked audio to use a cancelling auralizer at their respective locations to create a common acoustic space or set of acoustic spaces shared among subgroups of participants. For example, there are a set of network connected nodes, and the nodes can contain speakers and microphones, as well as participants and node mixing-processing blocks. The node mixing-processing blocks generate and manipulate signals for playback over the node loudspeakers and for distribution to and from the network. This processing can include cancellation of loudspeaker signals from the microphone signals and auralization of signals according to control parameters that are developed locally and from the network. A network block can contain network routing and processing functions, including auralization, synthesis, and cancellation of audio signals, synthesis and processing of control parameters, and audio signal and control parameter routing.
A vibrational energy harvester (100, 200, 300, 400) comprises a first mass (101, 201, 301) comprising a first internal cavity (102, 202, 302) and a second mass (103, 203) disposed within and configured to move within the first internal cavity. Movement of the second mass relative to the first mass induces an electrical current in one of the first mass and the second mass. The vibrational energy harvester also comprises a housing (104, 204, 404) comprising a second internal cavity (105, 405). The first mass is disposed within and configured to move within the second internal cavity. An adjustment mechanism (419) is also provided, configured to adjust a size of the second internal cavity.
Carbon fibre precursors for use in the formation of carbon fibre materials. The carbon fibre precursors comprise fibres of polymeric material which have a coating layer thereon, the coating layer comprising a material susceptible to dielectric heating, for example carbon nanotubes. The carbon fibre precursors may be suitable for forming into carbon fibres using a dielectric heating step, despite the fibres of polymeric material not being susceptible to dielectric heating, without adversely affecting the structure and physical properties of the main body of the carbon fibre so formed. A method of preparing a carbon fibre precursor for a carbon fibre formation process and a method forming a carbon fibre are also disclosed.
D01F 9/00 - Filaments, ou similaires, faits par l’homme, formés d’autres substancesLeur fabricationAppareils spécialement adaptés à la fabrication de filaments de carbone
D06M 11/74 - Traitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec du carbone ou du graphiteTraitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec des carburesTraitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec des acides graphitiques ou leurs sels
D06M 15/356 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone d'autres composés non saturés contenant des atomes d'azote, de soufre, de silicium ou de phosphore
D01F 6/94 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de mélanges de produits de polycondensation comme constituant majeur avec d'autres polymères ou des composés de bas poids moléculaire d'autres produits de polycondensation
72.
Integrated switching regulator device using mixed-core inductors
An integrated switching regulator device has a switching mode regulator comprising an input voltage source and a switching circuit coupled to the input voltage source configured to generate a pulsed voltage from the input voltage. A low pass filter is coupled to the switching regulator and is configured to filter the pulsed voltage to provide a regulated voltage to a load. The low pass filter comprises at least two LC stages, wherein the first LC stage comprises an air cored inductor and each subsequent LC stage comprises a non-air cored inductor. The switching circuit comprises two or more switching elements configurable to operate at a switching frequency of several megahertz.
H02M 1/14 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu
H02M 3/158 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation comprenant plusieurs dispositifs à semi-conducteurs comme dispositifs de commande finale pour une charge unique
H02M 1/00 - Détails d'appareils pour transformation
73.
Formulation for 3D printing and a 3D printed article
A flowable liquid formulation for 3D printing is described. The formulation comprises from 0.1 to 25 wt. % radiopaque particles, wherein at least 50% by weight of the particles have a diameter of at most 100 nm. The formulation further comprises monomeric, oligomeric and/or polymeric precursors adapted for polymerization to form a solidified article. Also described is an article (100) formed by 3D printing, the article (100) comprising a first 3D printed region (110) having a first radiopacity and a second 3D printed region (120) having a second radiopacity, wherein the first radiopacity is greater than the second radiopacity. Also described is a method of forming the article (100).
B33Y 80/00 - Produits obtenus par fabrication additive
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A61L 31/18 - Matériaux au moins partiellement opaques aux rayons X ou au laser
A composition for use in the formation of a lignin-based carbon fibre precursor is disclosed. The composition is a blend of a lignin and at least 10 wt % of a thermoplastic elastomer. The thermoplastic elastomer may improve the mechanical properties of the lignin-based blend to the extent that conventional carbon fibre precursor formation processes can be carried out using the blend whereas said processes would have been problematic and/or failed when using only lignin to form the carbon fibre precursors. The thermoplastic elastomer is suitably a thermoplastic polyurethane. A carbon fibre precursor produced using the composition is also disclosed, as is a carbon fibre produced from said carbon fibre precursors. Methods of forming said carbon fibre precursors and carbon fibres are also disclosed.
C08L 97/00 - Compositions contenant des matières contenant de la lignine
C01B 32/05 - Préparation ou purification du carbone non couvertes par les groupes , , ,
D01F 8/02 - Filaments, ou similaires, faits par l’homme, conjugués, c.-à-d. à plusieurs composantsLeur fabrication à partir de cellulose, de dérivés de la cellulose, de protéines
D01F 8/16 - Filaments, ou similaires, faits par l’homme, conjugués, c.-à-d. à plusieurs composantsLeur fabrication à partir de polymères synthétiques avec au moins un autre composé macromoléculaire obtenu par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone comme constituant
D01F 9/24 - Filaments de carboneAppareils spécialement adaptés à leur fabrication par décomposition de filaments organiques à partir de produits de polyaddition, de polycondensation ou de polymérisation à partir de composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
75.
A METHOD OF DETERMINING THE PROBABILITY OF INFLAMMATORY BOWEL DISEASE IN A SUBJECT BEING ULCERATIVE COLITIS OR CROHN'S DISEASE
The Applicant has discovered a cytokine profile that can accurately distinguish between ulcerative colitis (UC) and Crohn's disease (CD) in a subject having, or having symptoms of, inflammatory bowel disease (IBD). The profile of ulcerative colitis is increased IL-10 levels (compared with a reference IL-10 level, and decreased IL-23 levels (compared with a reference IL-23 level). The cytokine profile can be detected at a protein or genomic level, and is generally determined from a peripheral blood sample (i.e. a blood fraction such as serum, plasma, or blood cells such as peripheral blood mononuclear cells). Distinguishing between UC and CD in a subject with IBD allows a clinician prescribe a suitable therapeutic regime for the subject using a non-invasive blood test, and avoiding the need for scoping or tissue biopsy, which are undesirable for the subject. The cytokine profile can also be used to monitor a therapeutic regime for effectiveness.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
A multicomponent crystal (or co-crystal) comprising a first active pharmaceutical ingredient and a second active pharmaceutical ingredient. The multicomponent crystal is formed / sustained by non- covalent interactions between the nitrogen-containing heterocycle alpha-substituted with an amino group of the first active pharmaceutical ingredient and a carboxylic acid group of the second active pharmaceutical ingredient, suitably as well as other further non-covalent interactions with other H-bond forming groups. The multicomponent crystal may provide an improved multidrug dosage form comprising lamotrigine and valproic acid as the first and second active pharmaceutical ingredients, respectively. A pharmaceutical composition comprising a therapeutically effective amount of the multicomponent crystal and a pharmaceutically acceptable excipient, and a method of forming the multicomponent crystal, are also provided.
A61K 31/19 - Acides carboxyliques, p. ex. acide valproïque
A61K 31/53 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec trois azote comme seuls hétéro-atomes d'un cycle, p. ex. chlorazanil, mélamine
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
C07D 253/02 - Composés hétérocycliques contenant des cycles à six chaînons comportant trois atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe non condensés avec d'autres cycles
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
77.
IMPROVEMENTS IN AND RELATING TO COMPOSITE MANUFACTURING
A spreading apparatus for use with fibre-reinforced composite tapes, and related methods are disclosed. The spreading apparatus comprises an input side to receive an incoming tape to be spread, and an output side from which tape is delivered after spreading. The apparatus further comprises a tape heater (150, 250, 650) to in use apply heat to a tape; and a tape spreader (100, 1, 200, 600) to in use to apply contact pressure to the heated tape to thereby spread the tape.
An ostomy attachment comprises a flexible annular seal configured to embrace a stoma and a spout that in use is disposed beneath the stoma and configured to collect ostomy output at skin level and direct ostomy output away from the patient and annular seal and into an ostomy bag, in which the flexible annular seal is formed from an absorbent material and the spout is formed from a non-absorbent material. The annular seal may be an open ring comprising at least one mouldable arm that in use can be wrapped at least partially around the patients' stoma.
A61F 5/44 - Dispositifs portés par le patient pour recueillir l'urine, les selles, les menstrues ou d'autres sécrétionsDispositifs de colostomie
A61F 5/443 - Dispositifs portés par le patient pour recueillir l'urine, les selles, les menstrues ou d'autres sécrétionsDispositifs de colostomie comportant des joints d'étanchéité de type hydrocolloïde, p. ex. gels, empois d'amidon, gomme Karaya
A61F 5/448 - Moyens d'assujettissement du sac à l'anneau d'étanchéité
A thermoelectric material comprising carbon nanotubes and lignin. The carbon nanotubes are present as fibres and the lignin is present in pores and/or voids in the carbon nanotube fibres. The lignin may act as a dopant to increase the thermoelectric efficiency of the carbon nanotubes, multi-walled carbon nanotubes in particular. A method of forming a thermoelectric material involving impregnating fibres of carbon nanotubes with lignin, is also provided. A thermoelectric element, a fabric and a thermoelectric device comprising the thermoelectric material are also provided. The thermoelectric material may be particularly useful for the production of wearable thermoelectric devices.
73 Abstract "Treatment of immune dysregulation disorders" An isolated protease comprising a polypeptide having the structure is described: P-A-B5 in which P is a protease domain, A is an A-domain, and B is a B-domain, of a Group VII to XIII cell envelope protease (CEP), wherein the protease does not have a PA domain. An isolated protease according to Claim 1, selected from a wild-type Group VII to XIII cell envelope protease. The use of the protease as a medicament is treating immune dysregulation diseases is also described.10 (Fig. 8)
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
Concepts for linking source code with compliance requirements are presented. One example comprises analyzing a set of compliance requirements to identify one or more compliance topics. The example further comprises determining keywords for the identified one or more compliance topics. An item of source code is then analyzed to identify occurrences of the keywords in the source code. Mapping information representing a relationship between the item of source code and the compliance requirements is then generated based on the identified occurrence of the keywords.
H01L 41/18 - Emploi de matériaux spécifiés pour des éléments piézo-électriques ou électrostrictifs
G06N 10/00 - Informatique quantique, c.-à-d. traitement de l’information fondé sur des phénomènes de mécanique quantique
C07C 229/08 - Composés contenant des groupes amino et carboxyle liés au même squelette carboné ayant des groupes amino et carboxyle liés à des atomes de carbone acycliques du même squelette carboné le squelette carboné étant acyclique et saturé ayant un seul groupe amino et un seul groupe carboxyle liés au squelette carboné l'atome d'azote du groupe amino étant lié de plus à des atomes d'hydrogène
G06N 5/04 - Modèles d’inférence ou de raisonnement
A device for securing a catheter, or similar flexible medical tube or medical device to the skin of a patient. The device comprises a planar body (1) at least a lock retainer (5) and a passive retainer (6), both spaced-apart from each other. Furthermore a method of securing a catheter to a patient using a device as described.
A method of capturing water from a gaseous composition comprising water vapour (suitably air), the method comprising: (a) providing a metal-organic material; and (b) contacting themetal-organic material with water and/or water vapour; wherein upon contact with water and/or water vapour the material switches from a first state to a second state wherein the second state is able to retain a higher amount of water than the first state.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
An electromagnetic pump (100). The electromagnetic pump (100) comprises a conduit (101) comprising an inlet (103) and an outlet (105). A first magnetic field generating unit (109) is provided for generating a first magnetic field having a first component with a first direction in the conduit. A second magnetic field generating unit (111) is provided for generating a second magnetic field having a second component with a second direction in the conduit (101), the second direction being substantially opposite to the first direction. A piston member (113) is disposed within the conduit, the piston member (113) being moveable within the conduit (101) under the influence of the first and/or second magnetic fields to pump fluid received from the inlet (103) of the conduit (101) to the outlet (105) of the conduit (101).
F04B 17/04 - Pompes caractérisées par leur combinaison avec des machines motrices ou moteurs particuliers qui les entraînent ou par leur adaptation à ceux-ci entraînées par des moteurs électriques utilisant des solénoïdes
F04B 19/00 - "Machines" ou pompes ayant des caractéristiques particulières non prévues dans les groupes ou présentant un intérêt autre que celui visé par ces groupes
F02M 37/08 - Alimentation au moyen de pompes entraînées entraînées par moyen électrique
F04B 35/04 - Pompes à piston spécialement adaptées aux fluides compressibles et caractérisées par les moyens d'entraînement de leurs organes de travail ou par leur combinaison avec les machines motrices ou moteurs qui les entraînent ou bien par leurs adaptations à cet effet, non prévues ailleurs les moyens étant électriques
A securement device (1) for securely attaching tubular articles to surfaces comprising an anchor pad (3) for placing the securement device (1) on the surface, a substantially cylindrical base (4) on the anchor pad (3) and a screw cap (5) rotatably mountable on the base (4) at a screw mounting (6) defined between the base (4) and the screw cap (5) between an article receiving position and an article gripping position in which radial pressure is applied to the article placed in the securement device (1) to securely hold the article without the use of external adhesive fixings and prevent micro-pistoning of the article.
A61M 25/02 - Dispositifs de maintien en position, p. ex. sur le corps
F16L 3/12 - Supports pour tuyaux, pour câbles ou pour conduits de protection, p. ex. potences, pattes de fixation, attaches, brides, colliers entourant pratiquement le tuyau, le câble ou le conduit de protection comportant un élément entourant pratiquement le tuyau, le câble ou le conduit de protection
H02G 3/32 - Installations de câbles ou de lignes sur les murs, les sols ou les plafonds utilisant des colliers de fixation
F16G 11/10 - Agrafes à fermeture rapidePinces serrant uniquement dans un sens
B01D 15/38 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction spécifique non couverte par un ou plusieurs des groupes , p. ex. chromatographie d'affinité, chromatographie d'échange par ligand ou chromatographie chirale
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
A method and apparatus for real-time in-mould marking of a moulded or cast form with an identifier in which a configurable marking module (1) with phase change actuators (23) in the form of a multi-layered printed circuit board assembly (1) with a vertical element (33) having a marker (21) is installed in a mould (2), (35), the marker (21) being remotely configurable by a controller to create a unique identifier which is applied to the form in the mould.
B22C 23/02 - Dispositifs pour enduire les moules ou noyaux
B22D 17/22 - Moules métalliquesPlaques de moulesSupports de moulesÉquipement de refroidissement des moulesAccessoires pour l'extraction et l'éjection des pièces hors du moule
B29C 33/42 - Moules ou noyauxLeurs détails ou accessoires caractérisés par la forme de la surface de moulage, p. ex. par des nervures ou des rainures
B22D 17/20 - AccessoiresCoulée sous pression ou moulage par injection, c.-à-d. moulage en introduisant le métal dans le moule sous haute pression Parties constitutives
B22C 23/00 - OutillageDispositifs de moulage non prévus ailleurs
89.
A PCB STRUCTURE FOR EMBEDDING ELECTRONIC COMPONENTS
A PCB, printed circuit board, structure for forming at least one embedded electronic component. The structure comprises a multi-layer PCB board comprising at least one through-hole via, the via comprising a plurality of electrodes vertically aligned within the via, each electrode comprising a plated ring; and an isolation section separating each of the electrodes.
H05K 1/11 - Éléments imprimés pour réaliser des connexions électriques avec ou entre des circuits imprimés
H05K 1/16 - Circuits imprimés comprenant des composants électriques imprimés incorporés, p. ex. une résistance, un condensateur, une inductance imprimés
H05K 3/00 - Appareils ou procédés pour la fabrication de circuits imprimés
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Product research and development; Research and development services; Research and development for others; Industrial process research; Industrial process development; Product development consultation; Product design and development; Product development for others; Development of industrial products; Development of industrial processes; Analysis of product development; Research and development of new products; Development of new technology for others; Analysis and evaluation of product development; Technical consultancy relating to product development; Design and development of new products; Technological services and research relating thereto; Consultancy in the field of technological research; Consultancy in the field of scientific research; Consultancy in the field of industrial research; Research and development of new products for third parties in the field of plastic materials; Laboratory research; Industrial research; Research services; Provision of research services; Industrial analyses and research services; Design of manufacturing methods; Technological services relating to manufacture; Engineering consultancy relating to manufacture; Quality control of manufactured goods.
A process for the preparation of a composite comprising a carrier particle and a plurality of drug nanoparticles. The process comprises providing a suspension of drug nanoparticles in the presence of a carrier particle, the carrier particle having an external surface that is functionalised with a surface treatment agent. The process simplifies isolation of drug nanoparticles from suspension.
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
The present invention relates to an isolated polypeptide having xylanase activity. Also disclosed are isolated polynucleotides encoding the polypeptide, recombinant host cells expressing the polypeptide, and methods for degrading lignocellulosic biomass using the polypeptide. The invention finds utility in the production of biofuels, in the paper and pulp industry, in clothing or leather softening, in the food industry such as baking, etc.
An adhesive composition degradable by dielectric heating. The adhesive composition comprises a thermosetting polymer and a material sensitive to dielectric heating. The material sensitive to dielectric heating is selected from any one or more of hollow nanospheres, nanotubes, nanorods, nanofibres, nanosheets, graphene, graphene derivatives, nano/micro hybrids and mixtures of two or more nanoscale particles. The adhesive composition may be particularly useful in the assembly and disassembly of parts, particularly parts which have complicated and/or blocked joined surfaces. A method of joining at least two parts of an article together and a method of disassembling at least two parts of an article, using the adhesive composition are also provided. The adhesive composition may provide a reworkable nano-composite adhesive. The adhesive composition may be used to reversibly bond a biomedical or dental implant to a part of a human or animal body.
A composition for use in the formation of a lignin-based carbon fibre precursor is disclosed. The composition is a blend of a lignin and at least 10wt% of a thermoplastic elastomer. The thermoplastic elastomer may improve the mechanical properties of the lignin-based blend to the extent that conventional carbon fibre precursor formation processes can be carried out using the blend whereas said processes would have been problematic and/or failed when using only lignin to form the carbon fibre precursors. The thermoplastic elastomer is suitably a thermoplastic polyurethane. A carbon fibre precursor produced using the composition is also disclosed, as is a carbon fibre produced from said carbon fibre precursors. Methods of forming said carbon fibre precursors and carbon fibres are also disclosed.
D01F 9/24 - Filaments de carboneAppareils spécialement adaptés à leur fabrication par décomposition de filaments organiques à partir de produits de polyaddition, de polycondensation ou de polymérisation à partir de composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
C08L 97/00 - Compositions contenant des matières contenant de la lignine
A method of processing an active pharmaceutical ingredient,the method comprising passing a precursor composition comprising the active pharmaceutical ingredient and a solvent through a twin screw extruder wherein the twin screw extruder is heated at ambient pressure.
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
96.
SYSTEM AND METHOD FOR CURRENT PULSE MATCHING TECHNIQUE IN A SWITCHED MODE POWER CONVERTER
The invention provides a circuit in a switched mode power supply converter, and method of controlling a circuit. The circuit comprises a current pulse matching circuit configured to negate output voltage disturbance/noise during switching operation of a power conversion. The current pulse matching circuit input is driven by, or from, a power converter switch node of the switched mode power supply converter. The current pulse matching circuit comprises a rate-of-voltage change detection circuit driven by the power converter switch node.
H02M 1/15 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu utilisant des éléments actifs
H02M 1/44 - Circuits ou dispositions pour corriger les interférences électromagnétiques dans les convertisseurs ou les onduleurs
H02M 3/155 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
H02M 1/14 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu
97.
AN INTEGRATED SWITCHING REGULATOR DEVICE USING MIXED-CORE INDUCTORS
The present invention provides an integrated switching regulator device which comprises a switching mode regulator comprising an input voltage source and a switching circuit coupled to the input voltage source to generate a pulsed voltage from the input voltage, and a low pass filter coupled to the switching regulator configured to filter the pulsed voltage to provide a regulated voltage to a load. The low pass filter comprises at least two LC stages, wherein the first LC stage comprises an air cored inductor and each subsequent LC stage comprises a non-air cored inductor. The switching circuit comprises two or more switching elements configurable to operate at a switching frequency of several MHz.
H02M 1/14 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu
H02M 3/158 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation comprenant plusieurs dispositifs à semi-conducteurs comme dispositifs de commande finale pour une charge unique
The invention describes an integrated switch mode power supply device comprising a switch mode regulator having a switching circuit coupled to an input voltage source to generate an output voltage from the input voltage and the switching circuit comprises at least two wide bandgap switches. An Nth order filter circuit is coupled to the switch mode regulator and configured to filter the output voltage to provide a supply voltage to a load, where N is greater than the integer two wherein the filter circuit comprises a LC or RC low pass filter comprising a plurality of LC or RC filter stages having a first filter stage and a last filter stage.
H02M 3/156 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation
H02M 3/158 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation comprenant plusieurs dispositifs à semi-conducteurs comme dispositifs de commande finale pour une charge unique
H02M 1/14 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu
G01R 25/00 - Dispositions pour procéder aux mesures de l'angle de phase entre une tension et un courant ou entre des tensions ou des courants
G05F 1/62 - Régulation de la tension ou de l'intensité là où la variable effectivement régulée par le dispositif de réglage final est du type continu en utilisant des sources de courant continu en série ou en opposition
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
H03F 3/19 - Amplificateurs à haute fréquence, p. ex. amplificateurs radiofréquence comportant uniquement des dispositifs à semi-conducteurs
99.
FORMULATION FOR 3D PRINTING AND A 3D PRINTED ARTICLE
A flowable liquid formulation for 3D printing is described. The formulation comprises from 0.1 to 25wt.% radiopaque particles, wherein at least 50% by weight of the particles have a diameter of at most 100 nm. The formulation further comprises monomeric, oligomeric and/or polymeric precursors adapted for polymerization to form a solidified article. Also described is an article (100) formed by 3D printing, the article (100) comprising a first 3D printed region (110) having a first radiopacity and a second 3D printed region (120) having a second radiopacity, wherein the first radiopacity is greater than the second radiopacity. Also described is a method of forming the article (100).
G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
2) to form the three-dimensional structure. The hybrid porous materials may have a high selectivity for acetylene and/or a high capacity for acetylene adsorption. The method may be particularly useful for the purification of ethylene gas contaminated with acetylene during an ethylene production/purification process. The method may be particularly useful for the large scale separation of acetylene from other gases such as ethylene and carbon dioxide, during an acetylene production/purification process.
B01D 53/04 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse avec adsorbants fixes
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
