Embodiments of the present disclosure provide a testing method and device on decision uncertainty, the method including: acquiring brain imaging data of a subject in a period from its receiving a target problem to its making a judgment on the target problem; extracting brain activity signals from a region of interest (ROI) in the brain imaging data, the ROI including at least one region among the anterior cingulate cortex, the lateral frontopolar cortex, and the ventral striatum; and obtaining, based on the brain activity signals, a first test result reflecting a degree of certainty of the subject on correctness of the judgment.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique
2.
DEVICE FOR PREDICTING PROGNOSIS OF AND PROVIDING MEDICATION GUIDANCE FOR PATIENT WITH PULMONARY ADENOCARCINOMA BASED ON IMMUNE MICROENVIRONMENT GENE GROUP AND COMPUTER-READABLE STORAGE MEDIUM
Disclosed in the present invention is a device for predicting the prognosis of and providing the medication guidance for a patient with pulmonary adenocarcinoma based on an immune microenvironment gene group in the field of diagnosis and a computer-readable storage medium. The technical problem to be solved by the present invention is how to predict the prognosis of a patient with lung cancer or provide guidance on medication for the patient. One technical solution of the present invention is a device for predicting the prognosis of a to-be-tested patient with pulmonary adenocarcinoma. The device can comprise an immunophenotyping model construction module, an immunophenotyping module and a prognosis prediction module. The to-be-tested patient is subjected to immune subtype typing based on 75 genes of an immune microenvironment gene group; and the prognosis of the to-be-tested patient with pulmonary adenocarcinoma is predicted or the clinical medication guidance of the to-be-tested patient is provided according to an immunophenotyped subtype. By using the device provided in the present invention, the prognosis of the patient with pulmonary adenocarcinoma can be effectively predicted, and the excessive use of chemotherapy can be avoided, which on the one hand can prevent the patient from bearing serious side effects caused by chemotherapy, and on the other hand can reduce the economic burden of the patient and society.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
G16B 40/00 - TIC spécialement adaptées aux biostatistiques; TIC spécialement adaptées à l’apprentissage automatique ou à l’exploration de données liées à la bio-informatique, p.ex. extraction de connaissances ou détection de motifs
3.
INTERPENETRATING NETWORK MICROBIAL HYDROGEL WITH NATURAL POLYSACCHARIDE AND PROTEIN AND PREPARATION METHOD THEREOF
The present disclosure belongs to the technical field of biomaterials and microbial immobilization, and relates to an interpenetrating network (IPN) microbial hydrogel with natural polysaccharides (PS) and proteins (PN) and a preparation method thereof. The natural PS of the hydrogel is selected from alginates, and the natural PN is selected from fibrous protein silk fibroin (SF) or methacrylated SF (SilMA). The natural PS and PN mimic extracellular PS and PN of aerobic granular sludge (AGS). Components in the hydrogel are uniformly mixed and each crosslinked to form an IPN. The natural PS undergoes ionic crosslinking, the SF in the natural PN undergoes self-assembly to form physical crosslinking, or the SilMA undergoes photocrosslinking. Loaded microbes uniformly adhere to a structure of the hydrogel. According to the preparation method of the hydrogel, a hydrogel precursor solution is sonicated and mixed with microbes, followed by bioprinting combined with crosslinking.
C12N 11/04 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique piégées à l’intérieur du support, p.ex. dans un gel ou dans des fibres creuses
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
C12N 1/12 - Algues unicellulaires; Leurs milieux de culture
The present invention relates to a method for preparing a photoresist-graphene conductive composite system. The present invention further relates to a photoresist-graphene conductive composite system obtained by means of the method, and the use thereof. The method of the present invention causes graphene to be sufficiently dispersed in a conductive composite system, such that the obtained conductive composite system has excellent electrical conductivity, mechanical properties and thermal conductivity, and has good application prospects in terms of sensors, conductive circuits, capacitors, electronic devices, surface adsorption materials, catalyst carriers, etc.
Yantai-Jingshi Institute of Material Genome Engineering (Chine)
Inventeur(s)
Chen, Xuebo
Wang, Chu
Shen, Lin
Wang, Juanjuan
Chen, Yue
Fang, Weihai
Feng, Peichuan
Abrégé
The present application provides a compound of general formula (I), capable of being used for an organic electroluminescent device as a guest material of a light-emitting layer. The compound contains a structure in which a natural heterocyclic ring coordinates with iridium (Ir), and a light-emitting wavelength of the compound can be effectively regulated. Using the compound as the guest material of the light-emitting layer facilitates the improvement of luminous efficiency and light stability of the organic electroluminescent device. In addition, the compound provided by the present application has a small molecular weight, is applied to a light-emitting layer, has a low evaporation temperature, and facilitates processing. The present application also provides a guest material of a light-emitting layer containing the compound of general formula (I), an organic electroluminescent device, and a display device.
Disclosed in the present invention is a multi-modal smart classroom edge computing control system. The system comprises an audio data collection unit, a panoramic image collection and AI computing unit, a network connection unit and a device control unit, wherein the audio data collection unit comprises a microphone assembly, which is used for acquiring a target sound; the panoramic image collection and AI computing unit comprises a panoramic camera, which is used for acquiring panoramic image data of the interior of a smart classroom; the network connection unit comprises a WiFi 6 wireless network unit, an optical fiber access unit and an RJ45 wired network unit, which are used for accessing common computing devices, IoT devices and other wireless devices; and the device control unit controls the IoT devices by means of an RS232 bus interface. In the multi-modal smart classroom edge computing control system used in the present invention, voice control, gesture control and multi-modal control methods are added, such that all devices are in interconnection and intercommunication with each other, and compared with the use of manual buttons alone, the use of the system can save time and is convenient and fast.
A mannose derivative is an isonitrile-containing mannose derivative of formula (I), including different linking groups X:
A radioactive preparation is provided, including a radiolabeled compound formed by radiolabeling the mannose derivative with a radionuclide. An application of the radioactive preparation in the diagnosis and treatment of tumors is also provided.
The present invention belongs to the technical field of radiopharmaceutical chemistry. Provided are a radioactive metal complex targeting a prostate specific membrane antigen and a labeling ligand thereof. The general structural formula of the radioactive metal complex is as follows in the specification. The labeling time of the radioactive metal complex is 5-15 min, the labeling yield is greater than 95%, the radiochemical purity of a product is greater than 95% as determined by radio-HPLC, and the product exhibits a high affinity and high specificity for the prostate specific membrane antigen, and is a potential diagnosis and treatment integrated radioactive metal complex targeting the prostate specific membrane antigen.
The present invention relates to the technical field of radiopharmaceutical chemistry and clinical nuclear medicine, and in particular, to an imidazonaphthyridine compound with affinity with a Tau protein, a method for preparing same, and use thereof. The imidazonaphthyridine compound has a structure represented by general formula (I). After being marked by radionuclide, the compound and a derivative thereof can be used for clinical nuclear medicine diagnosis of neurodegenerative diseases, particularly used for diagnosing diseases with Tau protein deposition characteristics including Alzheimer's Disease. The structure of the compound is represented by general formula (I).
The present invention relates to a marked fatty acid derivative, a precursor compound thereof, and use thereof in a contrast agent. The derivative is represented by formula I: wherein M is 99mTc or Re; R, R1, R2, R3, R4and R511212 are independently H, an aliphatic chain or an alicyclic; J, X, and Y are independently absent, or -O-, -S- or (II), and J, X, and Y are not simultaneously absent; R6-R14are independently H or an aliphatic chain, and R13and R14 are not H simultaneously; z is 1-6, a is 0-5, b is 0-5, and c is 0-3; d is 0-27, e is 0-27, f is 0-28, g is 0-7, and at least two of d, e, f and g are not 0. The present invention provides a completely novel structure type that can be used for preparing a novel myocardial metabolism contrast agent, possessing important clinical application prospects.
C07F 13/00 - Composés contenant des éléments des groupes 7 ou 17 de la classification périodique
A61K 49/06 - Préparations de contraste pour la résonance magnétique nucléaire (RMN); Préparations de contraste pour l'imagerie par résonance magnétique (IRM)
11.
PSMA-TARGETING RADIOACTIVE METAL COMPLEX CONTAINING NITRO AROMATIC HETEROCYCLIC GROUP AND PREPARATION THEREOF
1221114233122 are chelating agents or chelating structures. In the present invention, a nitro aromatic heterocyclic group and a PSMA-targeting group are both linked to a metal chelating agent (HBED-CC, DOTA, DOTA(GA)2, NOTA, AAZTA, etc.) for the first time, which is used for performing labeling with a radioactive metal nuclide such as 68Ga, 18F-AIF, 177Lu, 90Y, 44Sc, 225Ac, 212Pb, and 213Bi, and is expected to increase the uptake of a radioactive metal label by prostate cancer and accelerate the metabolism in a non-target organ by means of the synergistic effect of the nitroaromatic heterocyclic group in vivo, thus improving the diagnosis and treatment effect of radiopharmaceuticals on tumors.
C07K 5/037 - Peptides ayant jusqu'à quatre amino-acides dans une séquence entièrement déterminée; Leurs dérivés contenant au moins une liaison peptidique anormale la liaison anormale étant formée par la chaîne latérale d'un alpha-amino-acide, p.ex. gamma-Glu, epsilon-Lys, glutathion
C07K 5/062 - Dipeptides la chaîne latérale du premier amino-acide étant acyclique, p.ex. Gly, Ala
C07K 7/02 - Peptides linéaires contenant au moins une liaison peptidique anormale
C07D 403/12 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
Disclosed in the present invention are a quaternary ammonium salt compound, and a preparation method therefor and an application thereof. The general formula of the quaternary ammonium salt compound in the present invention is as follows: formula. According to the quaternary ammonium salt compound in the present invention, existing nitro labeling precursors are further improved, and aromatic amines are selectively quaternized, so that a labeling precursor having high stability and high labeling efficiency is prepared. By means of the labeling precursor, specific ligands targeting biological macromolecules in the body, especially targeting α7nAChR, can be prepared, and thus can be used as a radioactive or non-radioactive imaging agent for the diagnosis or treatment of Alzheimer's disease or other related diseases.
C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
C07C 51/41 - Préparation de sels d'acides carboxyliques par conversion de ces acides ou de leurs sels en sels ayant la même partie acide carboxylique
C07C 53/18 - Acides acétiques halogénés contenant du fluor
C07D 295/135 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de car avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes d'azote liés par des liaisons simples ou doubles avec les atomes d'azote du cycle et les atomes d'azote substituants séparés par des carbocycles ou par des chaînes carbonées interrompues par des carbocycles
The present invention relates to a compound targeting focal adhesion kinase and a preparation method for and an application of the compound. The compound targeting focal adhesion kinase of the present invention has the following general formula (I). The compound targeting focal adhesion kinase of the present invention is simple in structure and can be used as a labeling precursor, preferably as a radioactive labeling precursor. The compound targeting focal adhesion kinase of the present invention further has an application in targeting focal adhesion kinase, or a use in preparation of a tumor treatment drug, or a use in preparation of a tumor diagnosis imaging agent, and has a good application effect.
C07D 401/12 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
C07D 403/12 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
Embodiments of the present disclosure disclose a measuring device of zenith angle, which relates to the technical field of angle measurement and is used to measure solar zenith angle. A light receiving member includes solar panels, a support frame with a regular pyramid structure, and a first counterweight member. Light intensity processing circuits are electrically connected to the solar panels and determine a rotation angle of the support frame based on intensity of light received by each solar panel; a direction adjusting member is electrically connected to the light intensity processing circuits to adjust angles of the support frame in both vertical direction and horizontal direction. The embodiments of the present disclosure have a simple structure, and can avoid limitations on placement angles of the device, measure a zenith angle quickly and accurately, reduce measurement costs, and be made into a small-sized device to facilitate outdoor carrying.
G01S 3/781 - Radiogoniomètres pour déterminer la direction d'où proviennent des ondes infrasonores, sonores, ultrasonores ou électromagnétiques ou des émissions de particules sans caractéristiques de direction utilisant des ondes électromagnétiques autres que les ondes radio - Détails
G01S 3/786 - Systèmes pour déterminer une direction ou une déviation par rapport à une direction prédéterminée utilisant le réglage d'une orientation des caractéristiques de directivité d'un détecteur ou d'un système de détecteurs afin d'obtenir une valeur désirée du signal provenant de ce détecteur ou de ce système de détecteurs la valeur désirée étant maintenue automatiquement
H02S 20/32 - Structures de support mobiles ou réglables, p.ex. pour réglage de l’angle spécialement adaptées pour le suivi du soleil
15.
Benzene ring-containing glucose derivative and use thereof
Disclosed herein is a benzene ring-containing glucose derivative of formula (I):
1 is each independently
2 is hydrogen. This application also provides a radioactive drug, including a complex formed by the benzene ring-containing glucose derivative and a radionuclide. Use of the benzene ring-containing glucose derivative in the tumor treatment and diagnosis is further provided.
Provided are a long non-coding RNA (lncRNA) gene for increasing rice yield and the use thereof. The rice long non-coding RNA (lncRNA) gene named as XLOC_050158 is highly expressed 5 days after a primary caryopsis flowers and 12 days after a secondary caryopsis flowers, which is a typical case that the expression of lncRNA is delayed in the middle stage of rice caryopsis development. By means of constructing XLOC_050158 overexpressed rice and observing the phenotypes thereof, it is found that the grain weight of the secondary caryopsis of the overexpressed rice is increased and is close to the grain weight of the primary caryopsis, however, the plant height, panicle length, total number of single-spiked spikelets, number of primary spikelets and number of secondary spikelets of the overexpressed rice all have no significant changes.
The invention discloses a method for determining dynamic wetland boundary based on hydrology, organism and soil elements, including the following steps: step 1: extracting dynamic wetland hydrology boundary; step 2: obtaining data on wetland vegetation; step 3: obtaining data on wetland soil; step 4: simulating dynamic wetland vegetation boundary and dynamic wetland soil boundary according to the data from step 1 to step 3; step 5: determining dynamic wetland boundary; the invention can reflect the dynamic wetland boundary in multiple dimensions comprehensively and accurately.
G06F 30/28 - Optimisation, vérification ou simulation de l’objet conçu utilisant la dynamique des fluides, p.ex. les équations de Navier-Stokes ou la dynamique des fluides numérique [DFN]
The present invention relates to the technical fields of radiopharmaceutical chemistry and clinical nuclear medicine, and in particular to a mannose derivative and an application thereof. The mannose derivative is an isonitrile-containing mannose derivative which contains different linking groups X and has a structure as shown in a general formula (I). A radioactive preparation obtained by labeling the mannose derivative with radionuclide is high in uptake in tumors and good in tumor/non-target ratio, and is a novel tumor radiopharmaceutical worthy of popularization.
C07H 13/04 - Composés contenant des radicaux saccharide estérifiés soit par l'acide carbonique ou ses dérivés, soit par des acides organiques, p.ex. acides phosphoniques par des acides carboxyliques comportant les radicaux carboxyle estérifiants liés à des atomes de carbone acycliques
C07H 1/00 - Procédés de préparation des dérivés du sucre
C07H 13/08 - Composés contenant des radicaux saccharide estérifiés soit par l'acide carbonique ou ses dérivés, soit par des acides organiques, p.ex. acides phosphoniques par des acides carboxyliques comportant les radicaux carboxyle estérifiants liés directement à des carbocycles
C07F 13/00 - Composés contenant des éléments des groupes 7 ou 17 de la classification périodique
The present embodiment provides a method and device for testing decision uncertainty. The method comprises: acquiring brain imaging data of a subject during a period from receiving a target problem to making a judgment on the target problem; extracting a brain activity signal of a region of interest in the brain imaging data, the region of interest comprising at least one region among the anterior cingulate cortex, the lateral frontopolar cortex, and the ventral striatum; and according to the brain activity signal, obtaining a first test result reflecting the degree of certainty of the subject that the judgment is correct.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
A new-type intelligent pointer, comprising a pointer main body (1). A laser hole (6), an infrared emission LED (7) and a microphone pickup hole (5) are provided in the surface of one end of the pointer main body (1); a telescopic rod (10) and a charging interface (3) are arranged on the surface of the other end of the pointer main body (1); a function button (12) is arranged at a handheld end of the pointer main body (1); the pointer main body (1) comprises a control circuit board and a polymer battery (2); a laser pen controller, a camera controller, a recording module and an electronic whiteboard controller are integrated on the control circuit board; a display screen (9) is embedded in the surface of an upper portion of the pointer main body (1); a temperature probe (8) is embedded in the surface of a lower portion of the pointer main body (1); an indicating lamp (4) is arranged on the surface of the upper portion of the pointer main body (1) that is adjacent to the laser hole (6) and the infrared emission LED (7); and a power switch (11) is arranged on a side surface of the pointer main body (1). The functions of a telescopic rod body, laser indication, electronic whiteboard control, recording, portable non-contact temperature measurement, and infrared remote control are integrated on a traditional pointer, thereby enhancing teaching convenience and interactivity.
YANTAI-JINGSHI INSTITUTE OF MATERIAL GENOME ENGINEERING (Chine)
Inventeur(s)
Chen, Xuebo
Wang, Chu
Wang, Juanjuan
Chen, Yue
Fang, Weihai
Feng, Peichuan
Abrégé
The present application provides a compound of general formula (I), capable of being used for an organic electroluminescent device as a guest material of a light-emitting layer. The compound contains a structure in which a natural heterocyclic ring coordinates with iridium (Ir), and a light-emitting wavelength of the compound can be effectively regulated. Using the compound as the guest material of the light-emitting layer facilitates the improvement of luminous efficiency and light stability of the organic electroluminescent device. In addition, the compound provided by the present application has a small molecular weight, is applied to a light-emitting layer, has a low evaporation temperature, and facilitates processing. The present application also provides a guest material of a light-emitting layer containing the compound of general formula (I), an organic electroluminescent device, and a display device.
A rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at once is provided. At least two distillation flasks are included. The distillation flasks are connected in sequence and rotated along the same axis. A bracket is disposed at the lower part between the distillation flasks for support. Instead of one rotation axis, at least two axes are included. Each rotation axis is provided with at least one distillation flask. The number of condensers and the number of collecting flasks increase correspondingly with the number of distillation flasks. If the number of distillation flasks on one rotation axis is greater than 1, a connector is disposed between the condenser and a transmitter. The collecting flask can be changed into a collector with the function of accurately quantitating and discharging distillates. Each distillation flask may be connected to a concentrated liquid quantitative assembly.
B01D 3/08 - Distillation ou procédés d'échange apparentés dans lesquels des liquides sont en contact avec des milieux gazeux, p.ex. extraction dans des récipients en rotation; Atomisation sur disques tournants
B01D 3/02 - Distillation ou procédés d'échange apparentés dans lesquels des liquides sont en contact avec des milieux gazeux, p.ex. extraction dans des cornues ou bouilleurs
B01D 5/00 - Condensation de vapeurs; Récupération de solvants volatils par condensation
23.
BENZENE RING-CONTAINING GLUCOSE DERIVATIVE AND APPLICATION THEREOF
The present invention relates to the technical field of radiopharmaceutical chemistry and clinical nuclear medicine, in particular to a benzene ring-containing glucose derivative and an application thereof. The benzene ring-containing glucose derivative has a structure shown as general formula (I). A radioactive preparation obtained by labeling the benzene ring-containing glucose derivative using a radionuclide has high uptake in tumors and a good tumor/non-target ratio, and is a novel tumor radiopharmaceutical having popularization and application value.
C07H 13/08 - Composés contenant des radicaux saccharide estérifiés soit par l'acide carbonique ou ses dérivés, soit par des acides organiques, p.ex. acides phosphoniques par des acides carboxyliques comportant les radicaux carboxyle estérifiants liés directement à des carbocycles
C07F 13/00 - Composés contenant des éléments des groupes 7 ou 17 de la classification périodique
A61K 31/7135 - Composés contenant des métaux lourds
The present invention provides a rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate. A distillation flask is improved into a structure having a liquid discharge opening formed at the bottom, and/or a spherical collecting flask is improved into a structure having a liquid release opening formed at the bottom. Concentrated liquid and/or distillate can be discharged without dismounting the distillation flask and/or the collecting flask. In addition, fine metering scale tubes and quantitative capacity increase units are disposed at the liquid discharge opening and/or the liquid release opening, there is a valve on the top and another valve on the bottom of each tube, so that the constant subtle changes of the amount of concentrated liquid and/or distillate can be observed, and an accurate amount of concentrated liquid and/or distillate can be discharged.
B01D 3/08 - Distillation ou procédés d'échange apparentés dans lesquels des liquides sont en contact avec des milieux gazeux, p.ex. extraction dans des récipients en rotation; Atomisation sur disques tournants
The present disclosure provides dihydrazone compounds having high affinity to Aβ protein and Tau protein and derivatives thereof. The structure of the compounds is shown by formula (I)
The present disclosure provides dihydrazone compounds having high affinity to Aβ protein and Tau protein and derivatives thereof. The structure of the compounds is shown by formula (I)
C07C 251/88 - Hydrazones ayant également l'autre atome d'azote lié par une liaison double à un atome de carbone, p.ex. azines
C07D 295/135 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de car avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes d'azote liés par des liaisons simples ou doubles avec les atomes d'azote du cycle et les atomes d'azote substituants séparés par des carbocycles ou par des chaînes carbonées interrompues par des carbocycles
C07C 255/66 - Nitriles d'acides carboxyliques contenant des groupes cyano et des atomes d'azote liés de plus à d'autres hétéro-atomes, autres que les atomes d'oxygène de groupes nitro ou nitroso, liés au même squelette carboné avec les atomes d'azote liés de plus à des atomes d'azote ayant des groupes cyano et des atomes d'azote faisant partie de groupes hydrazine ou hydrazone liés au même squelette carboné
C07D 213/74 - Radicaux amino ou imino substitués par des radicaux hydrocarbonés ou par des radicaux hydrocarbonés substitués
C07D 213/64 - Un atome d'oxygène lié en position 2 ou 6
C07D 317/58 - Radicaux substitués par des atomes d'azote
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
The disclosure provides a metal ion source emitting device comprising a ceramic chamber, a leading-out electrode chamber and three cathodes hermetically connected, a trigger electrode fixed on a ceramic insulating element, a cathode target material fixed on an indirect cooling channel, a limiting element fixed on a fixed element, the fixed element fixing the indirect cooling channel on a cathode cooling pipe, the cathode cooling pipe fixed on a cathode flange, a trigger binding post connected with the trigger electrode, a leading-out electrode and an accelerating electrode arranged right below a cathode in the leading-out electrode chamber, and leading-out slits formed on the accelerating electrode and the leading-out electrode. According to the emitting device, three cathodes can operate simultaneously with only one anode, increasing irradiation area of an ion source, and improving the operating efficiency and energy utilization rate, with a more compact emitting source and larger processing area.
H01J 37/075 - Canons à électrons utilisant l'émission thermo-ionique de cathodes chauffées par bombardement de particules ou par irradiation, p.ex. par laser
H01J 37/32 - Tubes à décharge en atmosphère gazeuse
Guangdong Guangxin Ion Beam Technology Co., Ltd. (Chine)
Inventeur(s)
Liao, Bin
Ouyang, Xiao
Wang, Guoliang
Ouyang, Xiaoping
Luo, Jun
Pang, Pan
Chen, Lin
Zhang, Xu
Wu, Xianying
Ying, Minju
Abrégé
The present application discloses a surface treatment method of a polymer for 5G, belonging to the technical field of surface treatment of polymer. By injecting and adding the oxygen elements to the polymer, the polymer matrix elements and the injected atoms can form a blend structure, which can increase the surface roughness of the polymer, improve its bonding strength with the metal, and thus enhance its anti-peel strength. The surface treatment method of the application has the surface resistivity, surface roughness, water absorption and tensile properties of the polymer all considered. The equipment used in the invention has long service life and low cost, and can realize large-scale roll-to-roll production. The method can be popularized in polymer surface treatment.
A building earthquake resistance structure includes an integrally connected roof support frame, used for supporting a roof of a building independently from walls of the building; a plurality of support columns, fixedly connected to the roof support frame; an annular trench, arranged in the ground around the building; an annular damping frame, arranged within the annular trench, lower ends of the support columns being fixedly connected to the annular damping frame; a plurality of dampers, arranged between a bottom portion of the annular trench and the annular damping frame. An earthquake resistance method for the building earthquake resistance structure prevents damage caused by the roof collapsing during an earthquake by supporting the roof of the existing building in the ground via the support columns. The building earthquake resistance structure is easy to construct and suitable for transforming traditional old buildings.
E04H 9/02 - Bâtiments, groupes de bâtiments ou abris conçus pour résister à des situations extérieures anormales, p.ex. à des bombardements, à des séismes ou à des climats extrêmes, ou pour se protéger de ces situations résistant aux séismes ou à l'effondrement du sol
E04B 7/02 - Toits; Structure des toits en ce qui concerne l'isolation avec des pentes planes, p.ex. toits en bâtière
E04B 1/36 - Appuis ou autres supports permettant le mouvement
29.
Group application oriented transcranial brain atlas generation method, prediction method and prediction apparatus
The present invention discloses a transcranial brain atlas generation method, and discloses a group application oriented transcranial brain atlas prediction method and a corresponding transcranial brain atlas prediction apparatus. The transcranial brain atlas generation method includes the following steps: creating a cranial surface coordinate system at an individual level; establishing a transcranial mapping system used to connect a cranial location and a brain location; and constructing a transcranial brain atlas by using a two-step stochastic process in a Markov chain. According to the transcranial brain atlas provided in the present invention, invisible intracerebral atlas label information is projected onto a visible scalp, so that a researcher or a doctor may “directly” use these pieces of brain structure information and function atlas information, thereby greatly improving the function of the brain atlas during use of a transcranial brain mapping technology.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio
G06F 3/0354 - Dispositifs de pointage déplacés ou positionnés par l'utilisateur; Leurs accessoires avec détection des mouvements relatifs en deux dimensions [2D] entre le dispositif de pointage ou une partie agissante dudit dispositif, et un plan ou une surface, p.ex. souris 2D, boules traçantes, crayons ou palets
G06T 17/20 - Description filaire, p.ex. polygonalisation ou tessellation
G06T 7/143 - Découpage; Détection de bords impliquant des approches probabilistes, p.ex. la modélisation à "champs aléatoires de Markov [MRF]"
G06T 19/20 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie Édition d'images tridimensionnelles [3D], p.ex. modification de formes ou de couleurs, alignement d'objets ou positionnements de parties
A61B 8/08 - Détection de mouvements ou de changements organiques, p.ex. tumeurs, kystes, gonflements
G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
30.
Ion beam lithography method based on ion beam lithography system
The present invention discloses an ion beam lithography method based on an ion beam lithography system. The ion beam lithography system includes a roll-roll printer placed in a vacuum, and a medium-high-energy wide-range ion source, a medium-low-energy wide-range ion source and a low-energy ion source installed on the roll-roll printer. The ion beam lithography method includes: first coating a polyimide (PI) substrate with a dry film, etching the dry film according to a preset circuit pattern, then using the ion beam lithography system to deposit a wide-energy-range metal ion on the circuit pattern to form a film substrate, and finally stripping the dry film off the film substrate to obtain a printed circuit board (PCB).
H01J 37/317 - Tubes à faisceau électronique ou ionique destinés aux traitements localisés d'objets pour modifier les propriétés des objets ou pour leur appliquer des revêtements en couche mince, p.ex. implantation d'ions
H05K 3/02 - Appareils ou procédés pour la fabrication de circuits imprimés dans lesquels le matériau conducteur est appliqué à la surface du support isolant et est ensuite enlevé de zones déterminées de la surface, non destinées à servir de conducteurs de courant ou d'éléments de blindage
H05K 3/10 - Appareils ou procédés pour la fabrication de circuits imprimés dans lesquels le matériau conducteur est appliqué au support isolant de manière à former le parcours conducteur recherché
The present invention discloses a magnetic filter tube, and relates to the technical field of magnetic filters. The magnetic filter tube includes a first rectangular tube and a second rectangular tube, where one end of the first rectangular tube is fixedly connected to one end of the second rectangular tube; the other end of the first rectangular tube forms an inlet of the magnetic filter tube; the inlet of the magnetic filter tube is connected with a cathode target flange; the other end of the second rectangular tube forms an outlet of the magnetic filter tube; the outlet of the magnetic filter tube is connected with a vacuum chamber; an inner wall of the first rectangular tube and an inner wall of the second rectangular tube are each provided with a protrusion and a groove; the protrusion is filled with cold water.
Methods for detecting or imaging structures in the central nervous system (CNS), e.g., brain, and delivery of therapeutic or detecting agents to the CNS or brain. The methods involve polycyclic aromatic structures that often function as carbon quantum dots (CQDs).
C09K 11/65 - Substances luminescentes, p.ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du carbone
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites
B82Y 20/00 - Nano-optique, p.ex. optique quantique ou cristaux photoniques
C07D 471/00 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes du système condensé, au moins un cycle étant un cycle à six chaînons avec un atome d'azote, non prévus dans les groupes
C07D 471/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes du système condensé, au moins un cycle étant un cycle à six chaînons avec un atome d'azote, non prévus dans les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
Polycyclic compounds that are aromatic or partially aromatic, and are substituted with one or more alkyl groups having an amino group and a carboxylic acid group, and includes carbon quantum dots (CQDs) that contain these compounds. The compounds and CQDs have a selective affinity for cells that express LAT1 and for tumor cells, and can internalize within such cells. The compounds and CQDs are useful for imaging of such cells and for delivering cargo compounds to and into cells that express LAT1 and tumor cells. Methods for making and using these compounds and CQDs for bioimaging and targeting certain tissues, including tumors, are disclosed.
C09K 11/65 - Substances luminescentes, p.ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du carbone
B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
34.
ROTARY EVAPORATOR FOR ACCURATELY AND QUANTITATIVELY RECOVERING MULTIPLE SOLVENTS OR CONCENTRATING MULTIPLE SAMPLES AT ONE TIME
A rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at one time, one original distillation flask being changed to at least two, the distillation flasks being connected in series and rotated along the same axis, a bracket (13) supporting under the distillation flasks; one original axis of rotation being changed into two, each axis of rotation being provided with one or at least two distillation flasks connected in series, the number of condensers and collection bottles being increased correspondingly with the number of distillation flasks; if the number of distillation flasks on one axis of rotation is more than one, a connector (9) is arranged between the condenser and a transmission body (3), the distillation flask being heated using an electric heating belt (10), the collection bottle can be changed to a collector (6) with the function of accurately quantifying and discharging the fractions, and the distillation flasks can be connected to a concentrated liquid quantitative assembly (7), to implement accurate and quantitative recovery of multiple solvents or concentration of multiple samples at one time.
B01D 3/08 - Distillation ou procédés d'échange apparentés dans lesquels des liquides sont en contact avec des milieux gazeux, p.ex. extraction dans des récipients en rotation; Atomisation sur disques tournants
35.
MOLECULAR TYPING OF MULTIPLE MYELOMA AND APPLICATION
Disclosed are molecular typing of multiple myeloma and application thereof. Specifically, disclosed is a product comprising a substance for obtaining or detecting 97 gene expressions in multiple myeloma patients to be detected and an apparatus for operating a multiple myeloma Bayesian classifier. By using the product, the present invention identifies a gene module co-expressed with the MCL1 gene, thereby distinguishing molecular subtypes of multiple myeloma having different prognoses and bortezomib sensitivities.
G01N 33/574 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour le cancer
G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique
36.
QUANTUM DOT PHOTORESIST, QUANTUM DOT LIGHT-EMITTING LAYER OBTAINED THEREFROM, QLED COMPRISING QUANTUM DOT LIGHT-EMITTING LAYER, AND PREPARATION AND APPLICATION THEREOF
A quantum dot photoresist suitable for the photolithographic preparation of a quantum dot light-emitting layer (3) having nanoscale thickness. The photoresist comprises a photoresist mother liquor, quantum dots having thiol surface ligands and a carrier transport material. After the photoresist is patterned, a quantum dot light-emitting layer (3) having nanoscale thickness may be obtained to thereby be applied to a QLED. A quantum dot light-emitting layer (3) obtained from the quantum dot photoresist, which usually has a thickness of less than 100 nm, and which is suitable for preparing a QLED. A preparation for the quantum dot light-emitting layer (3), a QLED comprising the quantum dot light-emitting layer (3), and a light-emitting device, an illumination device and a display device comprising the quantum dot light-emitting layer (3) or QLED.
A composite porous membrane contains at least one porous base layer and at least one uniaxially stretched coating layer located on at least one side surface of the porous base layer. For example, the composite porous membrane comprises at least one porous base layer and at least one nanofiber-like non-polyolefin polymer porous layer oriented along the transverse stretching direction of the composite porous membrane and located on one or two side surfaces of the porous base layer, or the composite porous membrane comprises a biaxially stretched polypropylene porous base layer and a uniaxially stretched coating layer located on at least one side surface of the porous base layer. The composite porous membrane is coated with a coating solution prior to transversely stretching. The nanofiber-like non-polyolefin polymer porous layer may reduce cracking of the composite porous membrane in the machine direction.
B01D 53/22 - SÉPARATION Épuration chimique ou biologique des gaz résiduaires, p.ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
C08J 7/043 - Amélioration de l'adhésivité des revêtements en soi, p.ex. par formation d'apprêts
H01M 50/489 - Séparateurs, membranes, diaphragmes ou éléments d’espacement dans les cellules caractérisés par leurs propriétés physiques, p.ex. degré de gonflement, hydrophilicité ou propriétés pour court-circuiter
B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
H01M 50/474 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES - Détails de construction ou procédés de fabrication des parties non actives des cellules électrochimiques autres que les piles à combustible, p.ex. piles hybrides Éléments d’espacement dans les cellules Éléments d'espacement à l'intérieur des cellules autres que les séparateurs, les membranes ou les diaphragmes; Leurs procédés de fabrication caractérisés par leur position dans les cellules
38.
Triangular carbon quantum dots and compositions and uses thereof
Provided herein are triangular carbon quantum dots with narrow bandwidth emission, methods of making them, and methods of using such triangular carbon quantum dots, such as in multicolored LED displays.
C09K 11/65 - Substances luminescentes, p.ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du carbone
H01L 33/20 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué
B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p.ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
B82Y 20/00 - Nano-optique, p.ex. optique quantique ou cristaux photoniques
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites
B82Y 40/00 - Fabrication ou traitement des nanostructures
H01L 33/26 - Matériaux de la région électroluminescente
H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)
39.
Rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate
The present invention provides a rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate. A distillation flask is improved into a structure having a liquid discharge opening formed at the bottom, and/or a spherical collecting flask is improved into a structure having a liquid release opening formed at the bottom. Concentrated liquid and/or distillate can be discharged without dismounting the distillation flask and/or the collecting flask. In addition, fine metering scale tubes and quantitative capacity increase units are disposed at the liquid discharge opening and/or the liquid release opening, there is a valve on the top and another valve on the bottom of each tube, so that the constant subtle changes of the amount of concentrated liquid and/or distillate can be observed, and an accurate amount of concentrated liquid and/or distillate can be discharged.
B01D 3/08 - Distillation ou procédés d'échange apparentés dans lesquels des liquides sont en contact avec des milieux gazeux, p.ex. extraction dans des récipients en rotation; Atomisation sur disques tournants
A capillary focusing microbeam X-ray diffractometer, comprising: an X-ray source system (1), an X-ray filter (9), a capillary convergence X-ray lens (10), a receiving slit (11), a three-dimensional sample table (12), a goniometer (13), an X-ray detector (6), an electronics system (7), a control system (14), and a computer (8). A sample is placed on the sample table (12). The X-ray source system (1), the X-ray filter (9), and the capillary convergence X-ray lens (10) are located on the same straight line and are mounted at one side of the goniometer (13). The receiving slit (11) and the X-ray detector (6) are located on the same straight line and are mounted at the other side of the goniometer (13). The X-ray detector (6) is electrically connected to the electronics system (7) and the computer (8) in sequence. The control system (14) is respectively electrically connected to the three-dimensional sample table (12), the goniometer (13), and the computer (8). The diffractometer has two analysis modes of micro-area X-ray diffraction analysis and micro-area energy dispersion X-ray fluorescence analysis. A phase structure of a small sample or a sample micro-area can be measured, and distribution of phases or elements can be detected by means of two-dimensional continuous scanning.
G01N 23/20008 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p.ex. rayons X ou neutrons, non couvertes par les groupes , ou en utilisant la réflexion de la radiation par les matériaux - Détails de construction des appareils d’analyse, p.ex. caractérisés par la source de rayons X, le détecteur ou le système optique à rayons X; Leurs accessoires; Préparation d’échantillons à cet effet
G01N 23/223 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p.ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux en irradiant l'échantillon avec des rayons X ou des rayons gamma et en mesurant la fluorescence X
41.
FLUORENONE LIGAND COMPOUND FOR α7 NICOTINIC ACETYLCHOLINE RECEPTOR AND USE THEREOF
1-41212122 is selected from amino, fluorine or a radioisotope of fluorine when X is (II). Various ligand compounds provided in the present invention have a relatively high affinity with the α7 nicotinic acetylcholine receptor, and are excellent ligand compounds for the α7 nicotinic acetylcholine receptor, and furthermore, the ligand compound for the α7 nicotinic acetylcholine receptor provided in the present invention can be used as a PET imaging agent or an SPECT imaging agent after being radiochemically labeled.
C07D 243/08 - Composés hétérocycliques contenant des cycles à sept chaînons comportant deux atomes d'azote comme uniques hétéro-atomes du cycle les atomes d'azote étant en positions 1, 4 non condensés avec d'autres cycles
C07D 295/135 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de car avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes d'azote liés par des liaisons simples ou doubles avec les atomes d'azote du cycle et les atomes d'azote substituants séparés par des carbocycles ou par des chaînes carbonées interrompues par des carbocycles
A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p.ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p.ex. kétorolac, physostigmine
A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p.ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p.ex. clozapine, dilazèpe
A61K 31/495 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec deux azote comme seuls hétéro-atomes d'un cycle, p.ex. pipérazine
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 25/18 - Antipsychotiques, c. à. d. neuroleptiques; Médicaments pour le traitement de la manie ou de la schizophrénie
A61P 25/14 - Médicaments pour le traitement des troubles du système nerveux pour traiter les mouvements anormaux, p.ex. chorée, dyskinésie
The present invention provides dihydrazone compounds having high affinity to Aβ protein and Tau protein and derivatives thereof. The structure of said compounds is as shown in formula (I): (I). Such compounds can be directly used as fluorescent probes for detecting neurofibrillary tangles in vivo or in a tissue sample, and when used in nuclear medicine imaging, the compounds need to be labelled using a suitable radioactive isotope. Such compounds are particularly useful for diagnosing patients with neurodegenerative diseases, including Alzheimer's disease, having the characteristics of Aβ plaques and neurofibrillary tangles.
The present invention discloses a compound of anilino polyethylene glycol ether cycloquinazoline substituted with a substituted arylmethyl heteroatomic group having the structure of formula (I) below, or a pharmaceutically acceptable salt, ester or solvate thereof, and a pharmaceutical composition comprising the same. The compound and pharmaceutical composition disclosed herein can be used in tumor targeted therapy and in the regulation of tumors and related diseases.
A61K 31/519 - Pyrimidines; Pyrimidines hydrogénées, p.ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à quatre chaînons, p.ex. taxol
A61K 31/44 - Pyridines non condensées; Leurs dérivés hydrogénés
A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée
C07D 491/056 - Systèmes condensés en ortho avec au moins deux atomes d'oxygène comme hétéro-atomes du cycle contenant de l'oxygène
45.
HEAVY METAL REMOVING PREPARATION, SYNTHESIS METHOD FOR SAME, AND APPLICATIONS THEREOF
The present invention relates to a heavy metal removing preparation, a synthesis method for same, and applications thereof. The synthesis method comprises the following specific steps: (1) with a dichloroalkane and ammonia serving as reaction raw materials, performing amination and oligomerization reactions in an alkaline condition; and, (2) adding carbon disulfide to the system produced in step (1) and reacting in an alkaline condition, thus completing the process; the method further comprises the removal of ammonia. The synthesis of the heavy metal removing preparation described in the present invention has the inexpensive dichloroalkane and ammonia serving as the raw materials, undergoes two reactions, is inexpensive, and has a high yield. The present invention overcomes the disadvantage and shortcoming of the prior art in which ethylenediamine is used as the raw material and significantly reduces production costs; the heavy metal removing preparation produced retains stable heavy metal removing performance even in extremely low pH conditions and provides very significant effects in the actual removal of heavy metals in industrial wastewater from plating and smelting.
A measurement method for measuring the thickness of a soil layer based on magnetic susceptibility, related to the technical field of soil erosion monitoring. The method comprises: measuring the original magnetic susceptibility Kb of a surface soil layer of sampling point soil (S1); measuring the maximum magnetic susceptibility Km with a magnetic element placed on the surface soil layer (S2); burying the magnetic element at a preset depth below the sampling point soil to form a magnetic layer (S3); measuring a first magnetic susceptibility K1 of the surface soil layer directly above the magnetic layer (S4); after a preset time interval, measuring a second magnetic susceptibility K2 of the surface soil layer directly above the magnetic layer (S5); and calculating a thickness variation value of the soil layer on the basis of a conversion equation between the magnetic susceptibility of the soil layer and the thickness of the soil layer (S6). The measurement method for measuring the thickness of a soil layer based on magnetic susceptibility has extremely small or no disturbance to a sampling point soil layer, produces a measurement result quickly and accurately, obviates the need for any special manual maintenance, provides a great representation of the sampling point soil layer, and has high practicability in scientific research and field monitoring for soil resource protection and soil erosion monitoring.
G01B 7/06 - Dispositions pour la mesure caractérisées par l'utilisation de techniques électriques ou magnétiques pour mesurer la longueur, la largeur ou l'épaisseur pour mesurer l'épaisseur
47.
FLUORINATED CATIONIC POLYMERIZED MONOMER, AND SYNTHESIS AND APPLICATION THEREOF
A monomer compound of formula (I) and a method for preparing the monomer. Each variable is as defined in the description. According to the present monomer, by means of a click chemistry reaction between thiol and olefin, a perfluorinated alkane chain is introduced into an oxacycloalkane monomer by a succinate linking group, so that a photo-curable material is obtained by photo-curing of the obtained monomer cation.
C07D 305/06 - Composés hétérocycliques contenant des cycles à quatre chaînons comportant un atome d'oxygène comme unique hétéro-atome du cycle non condensés avec d'autres cycles ne comportant pas de liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes du cycle
48.
FLUORINE-CONTAINING CATIONIC POLYMERIZATION MONOMER, AND SYNTHESIS AND APPLICATION THEREOF
A monomeric compound of formula (I), wherein variables are as defined in the specification. The monomer is synthesized in high yield and fast by means of click chemistry reaction between mercaptan and alkene, and a basically perfluorinated alkane chain is introduced into an oxyheterocycloalkane monomer by means of a linking group containing a norbornane structure portion, so that a photo-curable film obtained by photo-curing the obtained monomer cations is high in surface hardness, low in surface energy, and good in hydrophobic and oleophobic properties, especially in resistance to oil stains. Further disclosed are a preparation method for the monomer, a polymer obtained from the monomer by ring-opening polymerization, and a photo-curable composition containing the monomer and a photo-curing material obtained by photo-curing the photo-curable composition.
C07D 305/06 - Composés hétérocycliques contenant des cycles à quatre chaînons comportant un atome d'oxygène comme unique hétéro-atome du cycle non condensés avec d'autres cycles ne comportant pas de liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes du cycle
C07D 303/16 - Composés contenant des cycles oxirane avec des radicaux hydrocarbonés, substitués par des atomes d'oxygène liés par des liaisons simples ou doubles par des radicaux hydroxyle estérifiés
C08G 65/22 - Ethers cycliques possédant en dehors du cycle au moins un atome autre que le carbone et l'hydrogène
A gelable system is formed by mixing lithium salts and small-molecule ether compounds such as cyclic ether compounds or straight-chain ether compounds, optionally added with inorganic nanoparticles, additives, other solvents and/or electrolytes; a gel system or solid system is formed by interaction between them (such as the formation of new complexes or self-assembly, etc.), and by ring-opening polymerization or polycondensation of the small-molecule cyclic ether compounds, or by addition-fragmentation chain transfer polymerization of the small-molecule straight-chain ether compounds, etc. The gel system or solid system not only has better safety in use than common gel systems or solid systems, but also better adjustability of strength. The strength of the formed gel can be improved from the source by changing composition and type of raw materials. The improvement in the strength enables the gel system to be expanded into the solid system, thereby further extending the application range of the gel system.
H01M 10/0565 - Matériaux polymères, p.ex. du type gel ou du type solide
H01G 11/56 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrolytes Électrolytes solides, p.ex. gels; Additifs pour ceux-ci
H01G 11/60 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrolytes Électrolytes liquides caractérisés par le solvant
H01G 11/62 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrolytes Électrolytes liquides caractérisés par le soluté, p.ex. sels, anions ou cations
H01M 10/0568 - Matériaux liquides caracterisés par les solutés
H01M 10/0569 - Matériaux liquides caracterisés par les solvants
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites
50.
Flexible all-solid-state lithium-ion secondary battery having gelable system containing lithium salt and ether compound, and preparation method thereof
A flexible all-solid-state lithium-ion secondary battery is prepared by placing a positive electrode and a negative electrode or optionally a separator of the lithium-ion secondary battery in a gelable system in which a solid electrolyte has not yet formed by a way of infiltration or coating, so that the surfaces and the interiors of the positive and negative electrodes are infiltrated by the gelable system, which also fills the voids inside the positive and negative electrodes. When the gelable system is solidified to form the solid electrolyte, it can form the solid electrolyte in situ on the surfaces and interiors of the positive and negative electrodes. The lithium-ion secondary battery prepared by the method can form a conductive network inside the entire battery, which can not only extremely reduce the internal resistance of the lithium-ion secondary battery, thereby improving the conductivity and rate capability, but also solve the potential safety hazard problem caused by liquid electrolytes.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
H01M 10/0565 - Matériaux polymères, p.ex. du type gel ou du type solide
51.
Gelable system and uses thereof in lithium-air batteries, organic supercapacitors or capacitor batteries
A gellable system is suitable for use in lithium-air batteries, organic supercapacitors or capacitor batteries. The organic supercapacitors or capacitor batteries comprise a gel electrolytes and/or a solid electrolytes, which are prepared from a gellable system comprising the following components: (a) lithium salts and (b) ether compounds; the gellable system for lithium-air batteries also comprises (c) electrolytes or their solvents used in lithium-air batteries; in the system, the mass fraction of the gellable polymers and/or the gellable prepolymers is less than or equal to 1 wt %; by adjusting the composition and type of each component in the system, the gel and/or solid electrolytes, having adjustable strength, formation time, transition temperature, and also reversibility, can be prepared; the preparation method has simple procedure, mild reaction conditions, short reaction period, high yield, low manufacture cost, which makes it easy to realize industrialized production.
H01M 10/0565 - Matériaux polymères, p.ex. du type gel ou du type solide
H01G 11/56 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrolytes Électrolytes solides, p.ex. gels; Additifs pour ceux-ci
H01G 11/60 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrolytes Électrolytes liquides caractérisés par le solvant
H01G 11/62 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrolytes Électrolytes liquides caractérisés par le soluté, p.ex. sels, anions ou cations
The present disclosure provides a method and system for identifying plant species based on hyperspectral data, wherein the method includes: performing atmospheric radiation correction for the hyperspectral data of plants to be identified adopting Linear Regression method, to obtain corrected hyperspectral data, wherein, the hyperspectral data of the plants to be identified are collected by a hyperspectral ground object spectrometer provided within an unmanned aerial vehicle (UAV); performing external parameter orthogonalisation (EPO) processing for the corrected hyperspectral data; performing first order differential processing for the EPO processed hyperspectral data, to obtain hyperspectral data highlighting absorption peak information; performing discrete wavelet transformation processing for the hyperspectral data highlighting the absorption peak information, to obtain wavelet coefficients corresponding to the plants to be identified.
G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
G01N 21/17 - Systèmes dans lesquels la lumière incidente est modifiée suivant les propriétés du matériau examiné
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
Disclosed are molecular typing of multiple myeloma and application thereof. Specifically, disclosed is a product comprising a substance for obtaining or detecting 97 gene expressions in multiple myeloma patients to be detected and an apparatus for operating a multiple myeloma Bayesian classifier. By using the product, the present invention identifies a gene module co-expressed with the MCL1 gene, thereby distinguishing molecular subtypes of multiple myeloma having different prognoses and bortezomib sensitivities.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
G16B 40/00 - TIC spécialement adaptées aux biostatistiques; TIC spécialement adaptées à l’apprentissage automatique ou à l’exploration de données liées à la bio-informatique, p.ex. extraction de connaissances ou détection de motifs
54.
FISH DEATH FUNCTION-BASED FISH DEATH RISK DETERMINATION METHOD AND SYSTEM
A fish death function-based fish death risk determination method and system. Said method comprises: acquiring fish data, water body data and data on oxygen balance unsuitable for fish of a closed environment (S1); establishing a dissolved oxygen concentration change function according to the fish data, the water body data and the data on oxygen balance unsuitable for fish (S2); establishing a fish death function according to the fish data and the water body data (S3); using the dissolved oxygen concentration change function and the fish death function to establish an anoxic asphyxia dynamic change prediction model (S4); using the anoxic asphyxia dynamic change prediction model to predict, within a preset time, a dynamic trajectory of a dissolved oxygen concentration of a water body to be predicted and a dynamic trajectory of the number of deaths for each species of fish in the water body to be predicted (S5); and determining the fish death risk using the dynamic trajectory of the dissolved oxygen concentration and the dynamic trajectory of the number of dead fish. By combining the dynamic trajectory of the dissolved oxygen concentration with the dynamic trajectory of the number of dead fish, the method can determine the death risk for different fish species when faced with stress of asphyxia death of different degrees in cases where oxygen in the water body is deficient, thereby having high reliability.
G06Q 10/06 - Ressources, gestion de tâches, des ressources humaines ou de projets; Planification d’entreprise ou d’organisation; Modélisation d’entreprise ou d’organisation
55.
Individual-characteristic-based transcranial brain atlas generation method, navigation method, and navigation system
The present invention discloses an individual-level transcranial brain atlas generation method, where invisible intracerebral atlas information may be projected onto a visible scalp surface, so that an operational space and an effective space that are originally separated are fused together. For the problem of applying a transcranial brain atlas to guidance of individual placement of a transcranial device, the present invention further provides an individual-characteristic-based transcranial brain atlas generation method and navigation system. An experimental result indicates that, the present invention can be used to effectively improve coverage accuracy of a near-infrared measurement optrode in a brain region of interest, and consistency between measurement locations on upper cortexes of different persons, thereby improving sensibility of detecting a task-induced brain activity by using a near-infrared technology.
A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G06F 3/0354 - Dispositifs de pointage déplacés ou positionnés par l'utilisateur; Leurs accessoires avec détection des mouvements relatifs en deux dimensions [2D] entre le dispositif de pointage ou une partie agissante dudit dispositif, et un plan ou une surface, p.ex. souris 2D, boules traçantes, crayons ou palets
G06T 17/20 - Description filaire, p.ex. polygonalisation ou tessellation
56.
ROTARY EVAPORATOR CAPABLE OF AUTOMATICALLY CONTROLLING CONTINUOUS FEEDING AND DISCHARGING
Disclosed is a rotary evaporator capable of automatically controlling continuous feeding and discharging, comprising a bracket (1), wherein a detachable distilling flask (2) and a condenser (3) are fixed to the bracket (1), a receiving flask (4) is connected to the bottom of the condenser (3), a ventilation channel (5) is formed inside the condenser (3), the ventilation channel (5) is in communication with the distilling flask (2) and forms a ventilation tube (6) at a side wall of the condenser (3), and a ventilation valve (7) is provided at an atmosphere entry (30) of the ventilation tube (6) to control the communication of the interior of a distilling system with the atmosphere; the ventilation channel (5) is further internally provided with a feeding channel (8) and a discharging channel (9), and the feeding channel (8) and the discharging channel (9) are in respective communication with a feeding port (10) and a discharging port (11) formed at the ventilation tube (6) and are controlled by a feeding valve (12) and a discharging valve (13); and the feeding port (10) and the discharging port (11) are each connected to a power device, thereby realizing automatic feeding and discharging during the use of the rotary evaporator, and avoiding frequent manual operations.
B01D 3/08 - Distillation ou procédés d'échange apparentés dans lesquels des liquides sont en contact avec des milieux gazeux, p.ex. extraction dans des récipients en rotation; Atomisation sur disques tournants
A rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate. A distillation flask (2) is improved into a structure having a liquid discharge opening (11) formed at the bottom, and/or a spherical collecting flask (4) is improved into a structure having a liquid release opening (5) is formed at the bottom. Concentrated liquid and/or distillate can be discharged without removing the distillation flask (2) and/or the collecting flask (4). In addition, scaling tubes (7, 13) and quantitative capacity increase units (17, 18) are provided at the liquid release opening (5) and/or the liquid discharge opening (11), so that the constant subtle changes of the amount of concentrated liquid and/or distillate can be observed, and an accurate amount of concentrated liquid and/or distillate can be discharged.
B01D 3/08 - Distillation ou procédés d'échange apparentés dans lesquels des liquides sont en contact avec des milieux gazeux, p.ex. extraction dans des récipients en rotation; Atomisation sur disques tournants
Provided in the present invention are uses of a compound as represented by formula I in preparing a stem cell apoptosis antagonist. Also provided are uses of the compound as represented by formula I in preparing a medicament for preventing or treating cell apoptosis-related diseases, and a culturing method employing the compound as represented by formula I for stem cell culturing. The compound as represented by formula I is (I).
Provided herein are triangular carbon quantum dots with narrow bandwidth emission, methods of making them, and methods of using such triangular carbon quantum dots, such as in multicolored LED displays.
Disclosed is a class of non-linear optical crystals, and specifically disclosed is a class of deep ultraviolet non-linear optical crystal monoflurophospates. A monoflurophospate crystal is firstly used as a deep ultraviolet non-linear optical crystal, and the class of crystals are a class of fully new non-linear optical materials. The crystal shows an excellent optical performance, has a relatively large non-linear response, a relatively large polarizability (up to 25.6) and a relatively wide transparent range, can achieve phase matching, has a relatively large band gap (with band gaps all above 6.5 eV), a relatively high frequency multiplication factor and a relatively high birefringence, and can be used as a deep ultraviolet non-linear optical crystal with better performances.
Provided are a transcranial map generation method, and a transcranial map prediction method for group application and a corresponding transcranial map prediction apparatus. The transcranial map generation method comprises the following steps: creating a craniofacial coordinate system at an individual level; establishing a transcranial mapping system for connecting a cranial position and a brain position; and constructing a transcranial map by using a two-step random process in a Markov chain. The transcranial map projects invisible intracerebral map numeral information onto a visible epicranium, so that a researcher or a doctor can utilize the brain structures and functional map information, thereby greatly improving the effect of a brain map in a transcranial mapping technology.
Disclosed is an individual transcranial map generation method, by which invisible intracerebral map information can be projected onto a visible epicranium surface, so that an operation space and an efficacy space, which are originally separated from each other, are fused together. With respect to the problem of applying a transcranial map to the guidance of individualized placement of a transcranial device, the present invention further provides a transcranial map generation method based on individual features and a navigation system. Experimental results show that the coverage accuracy of the near-infrared measurement optrode encephalic region of interest and the consistency of epithelial layer measurement positions of different people can be effectively improved by means of the present invention, thereby improving the sensitivity of a near-infrared technology detection task for inducing brain activities.
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique
A debris flow model manufacturing method, wherein a hollow partition plate (3) is arranged within a debris flow simulation test trough (1), prepared solid materials having same densities and moisture levels can be filled in corresponding partition areas (31) according to sampling densities and moisture levels of corresponding area strata of a debris flow study region, and vibrations of a vibration table (2) cause the solid materials to be naturally and freely compacted under the effect of their own gravity, so as to form geological layers which conform to the debris flow study region in a layer-by-layer manner, and ultimately obtain a required debris flow model.
Disclosed in the present invention are a substituted heteroarylmethyl substituted anilino polyethylene glycol ether cycloquinazoline compound having a structure of formula (I) or pharmaceutically acceptable salt, ester and solvate thereof, and a pharmaceutical composition having same. The compound and the pharmaceutical composition disclosed in the present invention can be used for targeting therapy of tumors and regulating tumors and related diseases.
A building earthquake resistance structure, comprising: an integrally connected roof support frame (1), used for supporting a roof (100) of a building independently from walls (200) of the building; a plurality of support columns (2), fixedly connected to the roof support frame (1); an annular trench (3), arranged in the ground around the building; an annular damping frame (4), arranged within the annular trench (3), lower ends of the support columns (2) being fixedly connected to the annular damping frame (4); a plurality of dampers (5), arranged between a bottom portion of the annular trench (3) and the annular damping frame (4). An earthquake resistance method for the building earthquake resistance structure prevents damage caused by the roof (100) collapsing during an earthquake by supporting the roof (100) of the existing building in the ground via the support columns (2). The building earthquake resistance structure is easy to construct and suitable for transforming traditional old buildings.
E04B 1/98 - Protection contre d'autres agents indésirables ou dangers contre les destructions mécaniques, p.ex. par les raids aériens
E04H 9/02 - Bâtiments, groupes de bâtiments ou abris conçus pour résister à des situations extérieures anormales, p.ex. à des bombardements, à des séismes ou à des climats extrêmes, ou pour se protéger de ces situations résistant aux séismes ou à l'effondrement du sol
66.
COMPOSITE POROUS MEMBRANE AND PREPARATION METHOD THEREFOR AND USE THEREOF
Provided in the present invention are a composite porous membrane and a preparation method therefor and a use thereof, the composite porous membrane comprising at least one porous base layer and at least one uniaxially stretching coating layer located on at least one side surface of the porous base layer. Specifically, the composite porous membrane comprises at least one porous base layer and at least one nanofiber-like non-polyolefin polymer porous layer that is oriented along the transversely stretching direction of the composite porous membrane and located on one or two side surfaces of the porous base layer, or the composite porous membrane comprises a bidirectionally stretching polypropylene porous base layer and a unidirectionally stretching coating layer located on at least one side surface of the porous base layer. According to the preparation method, the composite porous membrane is prepared by introducing a coating liquid prior to transverse stretching, and the nanofiber-like non-polyolefin polymer porous layer that is oriented along the transverse stretching direction of the composite porous membrane may inhibit the longitudinal cracking of the composite porous membrane during use, and thus improve the performance during use of the composite porous membrane.
An anti-corrosive coating with self-repairing ability, comprising an anti-corrosive inner layer and a self-repairing surface layer. The material of the self-repairing surface layer mainly consists of polyaniline coated sodium alginate microcapsules and an epoxy resin, and the material of the anti-corrosive inner layer mainly consists of graphene oxide modified with boric acid and/or borax. A preparation method therefor comprises: preparing a material of an anti-corrosive inner layer, and coating the material of the anti-corrosive inner layer on a substrate to form the anti-corrosive inner layer; preparing a material of a self-repairing surface layer, and coating the material of the self-repairing surface layer on the anti-corrosive inner layer, to form the self-repairing surface layer; and forming an anti-corrosive coating. The anti-corrosive coating can prevent water pipelines from being corroded by liquid environments, and has a rapid self-repairing ability.
Provided is a ligand compound ofα7 nicotinic acetylcholine receptor, which can be represented by any one of the following general formulas, wherein (1) represents a halogen. The ligand compound is an improved ligand compound of α7 nicotinic acetylcholine receptor. The ligand compound can be used as a PET developer after being radio-chemically marked.
C07D 519/00 - Composés hétérocycliques contenant plusieurs systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un système carbocyclique commun non prévus dans les groupes ou
A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p.ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p.ex. clozapine, dilazèpe
A61K 31/501 - Pyridazines; Pyridazines hydrogénées non condensées et contenant d'autres hétérocycles
A61K 31/4439 - Pyridines non condensées; Leurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p.ex. oméprazole
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 25/18 - Antipsychotiques, c. à. d. neuroleptiques; Médicaments pour le traitement de la manie ou de la schizophrénie
A61P 25/14 - Médicaments pour le traitement des troubles du système nerveux pour traiter les mouvements anormaux, p.ex. chorée, dyskinésie
The present invention provides a gelatinized system containing ether compounds and a preparation method therefor and applications thereof. The gelatinized system is obtained by mixing lithium salts and small-molecule ether compounds (such as cyclic ether compounds or straight-chain ether compounds), optionally adding inorganic nanoparticles, additives, other solvents and/or electrolytes; by means of the interaction of the two objects (such as the generation of new complexes or a self-assembly effect, etc.) and open-loop polymerization or polycondensation of small-molecule ring ether compounds, or broken-chain polymerization with small-molecule straight-chain ether compounds, and a gel system or a solid-state system can be formed. The gel system or the solid-state system is not only superior to the ordinary gel system or the solid-state system in use safety, but also has a good strength adjustability, can change the contents and the types of components in raw materials, and can radically improve the strength of the formed gel. The change of the strength may allow the gel system to be extended to the solid-state system, thereby expanding the application range of the gel system.
Disclosed are a flexible all-solid-state lithium-ion secondary battery and a manufacturing method therefor. With regard to the flexible all-solid-state lithium-ion secondary battery, a lithium-ion secondary battery is placed, by means of infiltration and coating, in a gellable system not formed with a solid-state electrolyte by using a positive and negative electrode or an optional membrane, such that surfaces and the interior of the positive and negative electrode are infiltrated by the gellable system and the gellable system enters voids inside the positive and negative electrodes, and after being subjected to curing for forming the solid-state electrolyte, the gellable system can form the solid-state electrolyte on the surfaces of positive and negative electrode pieces and the interior thereof in situ. The lithium-ion secondary battery manufactured by means of the method can form a conductive network in the interior of the whole battery, which not only can greatly reduce the resistance inside the lithium-ion secondary battery, so as to improve the electrical conductivity and rate performance, but also can eliminate the safety hazards brought about by a liquid-state electrolyte.
Disclosed in the present invention are a gelatinized system and applications in a lithium air battery, a super capacitor or a capacitor battery in an organic system. The super capacitor or the capacitor battery in the organic system comprises a gel electrolyte and/or a solid electrolyte, which is prepared from a gelatinized system. The gelatinized system comprises the following components: (a) lithium salts; and (b) ether compounds. The gelatinized system for a lithium-air battery also comprises: (c) an electrolyte or a solvent thereof for a lithium air battery. The mass content of the gelatinized polymer and/or the gelatinized prepolymer in the system is less than or equal to 1wt%. By adjusting the content and the type of each component in the system, the gel and/or the solid electrolyte having an adjustable strength, an adjustable forming time, an adjustable transition temperature and reversibility can be prepared. The preparation method is simple, the reaction condition is moderate, the reaction period is short, the product yield is high, the preparation cost is low, and the industrialized production is easy to implement.
Disclosed is a simulation device for plants exposed to a shallow water wave environment for a long period of time, which can realize research on a physiological and biochemical response mechanism of the plants on a long time scale under different wave parameter conditions. The simulation device comprises a water tank (1), a plant cultivation box (2) built in the water tank (1), and a crank (3), a connecting rod (4) and a traction rod (5) which are hinged successively, with hinge shafts being parallel to each other, wherein the plant cultivation box (2) is connected to the non-hinged end of the traction rod (5), the crank (3) is connected to a power source (6), and the connecting rod (4) and the traction rod (5) drive the plant cultivation box (2) to perform a linear reciprocating movement in a horizontal direction at a sinusoidal changing speed relative to still water in the water tank (1), so as to simulate a state where plants are exposed to a shallow water wave environment for a long period of time.
A myricetin extract, prepared by an extraction method comprising the following steps: (1) plants of Myricaceae, Grape, Leguminosae or Camelliaceae are crushed, degreased and then dissolved in a methanol aqueous solution, and extracted by microwave and ultra-sonication to obtain an extract solution; (2) the extract solution obtained in step (1) is concentrated under a reduced pressure to obtain a concentrated solution, which is then filtrated under a reduced pressure and extracted with trichloromethane, and the resulting extract solution is collected, freeze-dried and pulverized; (3) a powder obtained in step (2) is dissolved in petroleum ether and then purified by means of silica gel column, so as to collect an eluate containing myricetin, which is then concentrated to obtain a crude product of myricetin; (4) the crude product of myricetin obtained in step (3) is added to a methanol aqueous solution having a volume ratio of 50-75%, and is heated to 75-80ºC till completely dissolved and then stirred, the extract is obtained following cooling and standing, crystallizing, filtrating and drying. The myricetin extract is used to prevent or treat tumor metastasis.
Disclosed are a class of diarylsulfide derivatives, a preparation method therefor, and the use thereof as a serotonin transporter-targeted imaging agent, belonging to the field of radiopharmaceutical chemistry. The diarylsulfide derivative has the structural formula (1) below, this class of compounds exhibits a high affinity for central SERT, and at the same time exhibits a high selectivity for SERT relative to DAT (a dopamine transporter) and to NET (a norepinephrine transporter). Therefore, [18F]-diarylsulfide derivatives can be used as an SERT/PET imaging agent.
C07C 323/37 - Thiols, sulfures, hydropolysulfures ou polysulfures substitués par des halogènes, des atomes d'oxygène ou d'azote ou par des atomes de soufre ne faisant pas partie de groupes thio contenant des groupes thio et des atomes d'azote, ne faisant pas partie de groupes nitro ou nitroso, liés au même squelette carboné ayant l'atome de soufre d'au moins un des groupes thio lié à un atome de carbone d'un cycle aromatique à six chaînons du squelette carboné ayant au moins un des atomes d'azote lié à un atome de carbone du même cycle aromatique à six chaînons non condensé le groupe thio étant un groupe sulfure l'atome de soufre du groupe sulfure étant lié de plus à un atome de carbone d'un cycle aromatique à six chaînons
C07C 319/20 - Préparation de thiols, de sulfures, d'hydropolysulfures ou de polysulfures de sulfures par des réactions n'impliquant pas la formation de groupes sulfure
C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
75.
SMALL MOLECULAR STEMAZOLE FOR PROMOTING STEM CELL CLONAL FORMATION AND APPLICATIONS THEREOF
Provided in the present invention are uses of a compound as represented by formula I in preparing a stem cell apoptosis antagonist. Also provided are uses of the compound as represented by formula I in preparing a medicament for preventing or treating cell apoptosis-related diseases, and a culturing method employing the compound as represented by formula I for stem cell culturing. The compound as represented by formula I is (I).
A method for recovering perfluorinated compound from sewage, which comprises the following steps: an electric flocculation step, using an electric flocculation method to adsorb the perfluorinated compound in an aqueous solution or a water-organic solvent mixed solution onto the surface of flocs produced by electric flocculation to form sludge; an elution step, carrying out an organic solvent elution treatment on the above-mentioned sludge containing perfluorinated compound to separate the perfluorinated compound from the sludge and form a concentrated perfluorinated compound solution; and a distillation step, distilling the produced concentrated perfluorinated compound solution to obtain perfluorinated compound solids and a distillate, the distillate being used as an elution liquid of the above-mentioned elution step. Zn(OH)2 flocs produced in situ by electric flocculation have a very high adsorption capacity and a fast adsorption rate for the perfluorinated compound and can recover high-concentration and low-concentration perfluorinated compounds from sewage and purify the sewage simultaneously. Since the electric flocculation treatment has low costs and low sludge production amount, the large-scale application of the method is economically feasible.
BEIJING NORMAL UNIVERSITY SCIENCE PARK CO., LTD. (Chine)
Inventeur(s)
Yang, Xiaojing
Du, Yien
Du, Dejian
Abrégé
Provided is a TiO2 nanocrystal and a synthesis method therefor, wherein the nanocrystal is an anatase-type TiO2 nanocrystal, and the exposed crystal plane thereof is perpendicular to the crystal zone axis [111]. The synthesis method comprises: adjusting the pH value of a colloidal suspension of a tetratitanic acid nanosheet used as a precursor to 1-4, and carrying out a hydrothermal reaction to obtain the TiO2 nanocrystal. The TiO2 nanocrystal is high in purity and uniform in particle size distribution, can be used for degrading a methyl blue solution and in a dye-sensitized solar cell, and has remarkably improved catalytic and photovoltaic performance, compared with commercial P25 TiO2.
BEIJING NORMAL UNIVERSITY SCIENCE PARK CO., LTD. (Chine)
Inventeur(s)
Yang, Xiaojing
Du, Yien
Du, Dejian
Abrégé
Provided is a synthesis method for a TiO2 nanocrystal, comprising: adjusting the pH value of a colloidal suspension of a tetratitanic acid nanosheet used as a precursor to 5-13; and carrying out a hydrothermal reaction on the precursor to obtain the TiO2 nanocrystal. The TiO2 nanocrystal synthesized by the method is anatase-type, the exposed crystal plane thereof is {010} crystal plane, and the method has low cost, no pollution, simple process, strong controllability, short production period and good repeatability, and is suitable for industrial production.
Disclosed is a method for concentrating, separating and removing a perfluorinated compound. The method comprises the following steps: an electrocoagulation step: using an electrocoagulation method to adsorb a perfluorinated compound in a water solution or a mixed solution of water and an organic solvent to the surface of a floc generated in electrocoagulation, so as to form sludge; and a centrifugation step: performing centrifugation on the sludge comprising the perfluorinated compound, so as to separate the perfluorinated compound from the sludge and generate a concentrated perfluorinated compound solution. By using the electrocoagulation method, the present invention has a simple technological process, is easy to operate, requires moderate reaction conditions, has low energy consumption and good treatment effect, is stable and reliable, and is easy for industrialized application; in addition, the centrifugal separation technology for harmless treatment of the generated sludge comprising the perfluorinated compound is novel, does not require addition of chemical reagents, realizes dehydration of the sludge while the harmless treatment is performed, requires simple devices and is easy for automatic operation.
An optical device for focusing synchrotron radiation light source is disclosed according to the present invention, so as to improve the uniformity of the light intensity of the emergent light, to increase the divergence the emergent light, and to restrain the synchrotron radiation higher harmonics. An outline generatrix of the optical device is a quadratic curve segment or a combination of a plurality of quadratic curve segments, the opening orientations of which are the same, and the optical device includes: a plurality of capillary bodies made of transparent material, wherein the capillary bodies in a center region have a solid construe; the capillary bodies in a periphery region located outside of the center region have a hollow structure.
G21K 1/02 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p.ex. pour focaliser ou pour modérer utilisant des diaphragmes, des collimateurs
C03C 13/00 - Compositions pour fibres ou filaments de verre
G21K 1/06 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p.ex. pour focaliser ou pour modérer utilisant la diffraction, la réfraction ou la réflexion, p.ex. monochromateurs
81.
METHOD FOR QUICKLY AND EFFECTIVELY REMOVING HEAVY METALS IN WATER BODY
A method for removing heavy metals in a water body, characterized in that the surface of zero-valent iron is oxidized and activated using the common oxidizing agents in water treatment such as hydrogen peroxide, sodium hypochlorite, potassium permanganate, etc., so as to continuously generate the active constituents of fresh iron (III) / (II) (hydro) oxide, etc., and the heavy metals including As, Hg, Cd, Pb, Cr, Se, Sb, Cu, Zn etc. in the water body are removed quickly and effectively by way of adsorption, precipitation, redox, etc.
Disclosed is a higher fatty acid derivative marked with Technetium-99m, being a long chain fatty acid metabolism drug. The long chain fatty acid metabolism drug introduces sulfonyl and thiophen ring to long chain fatty acid to eventually decrease liposolubility of molecules, increase intake of the drug in the myocardium, and extend the retention time of the drug in the myocardium.
Provided in the present invention is a set of gene groups for predicting or for the auxiliary prediction of the survival time prognosis of patients with neuroglioma, consisting of a PM gene group and an EM gene group with a total of 68 genes. A subtype marking gene group consisting of two major gene groups co-expressed with PDGFRA and EGFR can stably divide neuroglioma samples derived from different database sources into three specific subtypes, and can be applied to clinical diagnosis for neuroglioma and judging the survival time prognosis of patients with neuroglioma.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
84.
NITROGEN MUSTARD DERIVATIVES, METHOD OF PREPARING SAME, AND TUMOR TREATMENT APPLICATION
A new nitrogen mustard derivative of Formula I or a pharmaceutically acceptable salt thereof, where R is N(CH2CH2Cl)2. Experiments show that the compound can inhibit a phase of the cell in Phase G2/M and is a dual-function alkylating agent. In vivo antitumor activity experiments show that the compound has desirable activity. Moreover, this compound further has advantages that nitrogen mustard drugs do not, that is, low toxicity. Also, this compound is easy to synthesize and has a high total yield. These advantages show that this compound has a great potential to be used as tumor treatment drugs.
This invention provides the applications of PA200 in developing products; the functions of these products include at least one of the followings: (1) bind acetylated proteins; (2) promote degradation of acetylated proteins; (3) participate in somatic DNA damage repair; (4) participate in spermatogenesis.
The present invention relates to a process for preparing polysulfone, comprising reacting bisphenol monomers with a salt forming agent to form bisphenolate, followed by subjecting the bisphenolate and 4,4′-dihalodiphenyl sulfone to polycondensation to give polysulfone, characterized in that the reaction for forming bisphenolate and the polycondensation are performed in the presence of a composite ionic liquid as the solvent, the composite ionic liquid containing zwitterionic liquid of formula (I) and/or (II) as component A and ionic liquid of formula (III) and/or (IV) as component B, wherein variables are respectively defined in the description of the present invention. The process of the present invention enables a shortened preparation period of polysulfone, particularly a shortened reaction time (including the time of water removal) of the salt forming stage; in addition, the polysulfone thus prepared has an improved molecular weight which is much higher.
Provided is an optical device for focusing synchrotron radiation light sources, which is used for improving the uniformity of light intensity of emergent lights, enhancing the divergence of emergent light beams, and suppressing higher harmonics of synchrotron radiation. The outer generatrix of the optical device is a quadric curve section or a combination of a plurality of quadric curve sections, wherein the opening direction of the plurality of quadric curve sections are the same. The optical device comprises: a plurality of capillary bodies (102) made of transparent materials, wherein the capillary bodies (102) located in central area (201) have solid structures and the capillary bodies (102) located in peripheral area (202) outside the centre area (201) have hollow structures.
G21K 1/06 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p.ex. pour focaliser ou pour modérer utilisant la diffraction, la réfraction ou la réflexion, p.ex. monochromateurs
88.
POLY(P-HYDROXY STYRENE) DERIVATE CONTAINING SULFONIUM SALT PHOTO-ACID GENERATOR GROUP, SYNTHESIS PROCESS AND USE THEREOF
The present invention relates to a new macromolecular photo-acid generator based on poly(p-hydroxy styrene) (PHS), the synthesis process and use thereof in a chemically amplified photoresist. The poly(p-hydroxy styrene) derivate contains, on some of the benzene rings, sulfonium salt photo-acid generating groups and some of the phenolic hydroxyl groups are protected by acid decomposable protecting groups. When exposed to light, the acid-generating groups produce a strong acid, and the acid catalyzes the decomposition of the protecting groups under post-baking conditions, releasing phenolic hydroxyl groups, leading to an increase in alkali solubility of the exposed part, and the exposed part can develop and form images with diluted alkaline water. Therefore, the product can be used as a macromolecular acid generator or a novel chemically-amplified positive single-component photoresist material, and a chemically amplified resist capable of being used in deep ultra-violet photoetching, e-beam photoetching, and other next generation techniques for processing super large-scale integrated circuits, such as extreme ultra-violet photoetching, X-ray photoetching, etc.
C08F 8/34 - Introduction d'atomes de soufre ou de groupes contenant du soufre
G03F 7/00 - Production par voie photomécanique, p.ex. photolithographique, de surfaces texturées, p.ex. surfaces imprimées; Matériaux à cet effet, p.ex. comportant des photoréserves; Appareillages spécialement adaptés à cet effet
The present invention relates to a process for preparing polysulfone, comprising reacting bisphenol monomers with a salt forming agent to form bisphenolate, followed by subjecting the bisphenolate and 4,4'-dihalodiphenyl sulfone to polycondensation to give polysulfone, characterized in that the reaction for forming bisphenolate and the polycondensation are performed in the presence of a composite ionic liquid as the solvent, the composite ionic liquid containing zwitterionic liquid of formula (I) and/or (II) as component A and ionic liquid of formula (III) and/or (IV) as component B, wherein variables are respectively defined in the description of the present invention. The process of the present invention enables a shortened preparation period of polysulfone, particularly a shortened reaction time (including the time of water removal) of the salt forming stage; in addition, the polysulfone thus prepared has an improved molecular weight which is much higher.
The present invention provides an immunological adjuvant and vaccines comprising said adjuvant, wherein the major component of the adjuvant is recombinant human calcineurin B subunit.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p.ex. par les adjuvants chimiques
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
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