The present specification relates to apparatus, methods and kits for applying an identification tag to an animal and removing a tissue sample from the animal. Apparatus of the disclosure cannot be manipulated to transfer an identification tag from one animal to another. An apparatus can comprise a sample container, a flap, a downholder clip and a cutting element that can be placed on a male part of an ear-tag and at least one element/feature that supports movement of the sample container out of the movement path of the male tag toward the female part of the ear-tag.
The present specification relates to apparatus, methods and kits for applying an identification tag to an animal and removing a tissue sample from the animal. Apparatus of the disclosure cannot be manipulated to transfer an identification tag from one animal to another. An apparatus can comprise a sample container, a flap, a downholder clip and a cutting element that can be placed on a male part of an ear-tag and at least one element/feature that supports movement of the sample container out of the movement path of the male tag toward the female part of the ear-tag.
The present disclosure, according to one embodiment, describes a laboratory vessel for storing and treating a tissue sample comprises a closable opening, and additionally comprises a pipe part which is insertable in the opening of the laboratory vessel, wherein in inserted position, the pipe part seals against the laboratory vessel with its outer circumference and is clampingly displaceable with respect to said laboratory vessel, wherein a pestle is mounted in the laboratory vessel, over which the pipe part can be placed sealingly with its inner circumference. The laboratory vessel also comprises one or more tissue sample treatment agents. The tissue sample and the treatment agents are separated by placing the pipe part over the pestle, which separates a treatment agent region from a sample region.
G01N 1/08 - Dispositifs pour prélever des échantillons à l'état solide, p. ex. par coupe à l'outil impliquant un outil d'extraction, p. ex. mèche cylindrique creuse ou trépan
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemicals used in industry, laboratory analysis, (other than for medical or veterinary purposes), science (other than for medical or veterinary purposes); chemical compositions; diagnostic preparations (other than for medical or veterinary purposes); biological and biotechnological preparations (other than for medical or veterinary purposes); protein; antibodies for scientific and laboratory use. Pharmaceutical, veterinary and sanitary preparations; medicines for human and veterinary purposes; chemical preparations for medical, pharmaceutical and veterinary purposes; chemico-pharmaceutical preparations; diagnostic preparations for medical and veterinary purposes; vaccines; biological and biotechnological preparations for medical and veterinary purposes; bacterial and bacteriological preparations for medical and veterinary purposes; enzymes and enzyme preparations for medical and veterinary purposes; poisons; bacterial poisons, isotopes for medical purposes; germicides; preparations of microorganisms for medical and veterinary use; lotions for pharmaceutical and veterinary purposes; nutritive substances for micro-organisms; media for bacteriological cultures; narcotics; parasiticides; pills for pharmaceutical purposes; chemical reagents for medical and veterinary purposes; serums; serotherapeutic medicines; preparations of trace elements for human and animal use; vitamin preparations; antibodies; proteins; albuminous foodstuffs; albuminous preparations; ferments for pharmaceutical purposes. Surgical, medical and veterinary apparatus and instruments, in particular for extracting, applying, storing and transporting medical and veterinary preparations, samples, diagnostic preparations, medicines and vaccines. Medical, hygienic and beauty care, and veterinary and agricultural research services; chemical, biological, biotechnological, bacteriological, cosmetics, medical, veterinary and pharmacological research; physics (research) and technical research; research and development in the field of medical and veterinary diagnostic preparations; bacteriological research and analysis; providing scientific advice in the field of pharmacy.
To attach an ear tag (6, 10) to an ear (16) and to remove a sample (22) containing tissue of the ear therefrom, a mandrel (8), which is fastened to a mandrel region (6) of the ear tag, is brought by means of pliers (1) on a first movement path through the ear (16) into a hole (12) formed in a hole part (10) of the ear tag and anchored there, while the sample (22) is taken with the aid of a removal head (17) and is brought out of engagement with the hole (12) by interaction with the mandrel (8) with a movement component oriented transversely to the first movement path, before the mandrel (8) is anchored in said hole.
Method for the detection and classification of PRRSV-infections in swine herds, comprising a) the incubation of tissue samples taken from the animals with at least one antigen capable to bind a neutralizing antibody against the Type l-virus possibly present in the animal and with at least one antigen capable to bind a neutralizing antibody against the Type ll-virus possibly present in the animal, b) testing whether a binding of antibodies against the Type l-virus and/or the Type ll-virus has taken place and c) determining from the presence of possible epitope-antibody complexes whether an infection of the PRRSV l-Type and/or PRRSV ll-Type is present in the herd and diagnostic compositions for such a method.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
Disclosed is an ear tag comprising a spike plate (1) and a spike (2) which is fastened to the spike plate (1) at an end region and which bears a punching head (4) at its other end region, which punching head is designed to punch through an ear (23) and a hole plate (5) and can be sealingly accommodated in a container (16) arranged on the rear side of the hole plate (5) after penetrating same, the punching head (4) comprising a sample chamber (15), which serves to accommodate a punched-out ear sample (24) and which has an opening (28) that runs in the direction of punching (29) and that is surrounded by an annular blade (14), the container (16) having an opening (21) that runs contrary to the direction of punching (29) and that is provided for inserting the ear sample (24), characterised in that a plunger (19) is accommodated in the container (16), which plunger is designed to shut the opening (28) of the sample chamber (15) at a shutting end (22).
Sampling device for samples containing DNA in particular, with a sample-collecting area provided at the free end of an elongate holding device, wherein the sample-collecting area is designed to be separable from the sampling device.
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
G01N 1/02 - Dispositifs pour prélever des échantillons
A61F 13/38 - Tampons comportant une poignée en forme de bâtonnet, p. ex. bâtonnets ouatés
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (USA)
PRIONICS AG (Suisse)
Inventeur(s)
Orru, Christina, D.
Caughey, Byron, W.
Kuhn, Franziska
Schröder, Björn
Raeber, Alex
Abrégé
Methods are disclosed for detecting prions and/or prion disease-associated forms of prion protein. These methods provide sensitive and specific identification of prions in both biological and environmental samples. These methods include the use of both immunoprecipitation and an amplification assay that uses shaking in the absence of sonication, such as QuIC (SQ) or RT-QuIC (RTQ). In specific non- limiting examples, the methods include the use of monoclonal antibody 15B3 and/or RT-QuIC (RTQ), and/or a substrate replacement step.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
10.
CONTAINER FOR RECEIVING LAB SAMPLES, AND USE OF A DEVICE FOR TAKING SAMPLES
The invention relates to a container for receiving lab samples, wherein the samples are held in the container in a defined height range and distanced from the inner wall, and wherein a drying unit is arranged inside the container, at least in said height range, at least partially surrounding the samples from the side, said drying unit have drying agent and being so constructed that gas exchange is possible between the sample and the drying agent.
G01N 1/02 - Dispositifs pour prélever des échantillons
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
11.
METHOD FOR THE DETERMINATION OF TRICHINELLA INFECTIONS AND DIAGNOSTIC COMPOSITION FOR SUCH METHODS
Method for the determination of Trichinella infections in an animal or a human, comprising the incubation with Trichinella antigens of a tissue sample taken from the animal or the human, the processing of the tissue sample, the addition of anti-antibodies to the tissue sample, and the verification of whether binding of the anti-antibodies to any antigen/antibody complexes present in the tissue sample has taken place, where the anti-antibodies added are anti-IgG antibodies and simultaneously anti-IgM antibodies.
The invention relates to a sample container (10, 100, 500, 700) for biological sample material (23, 230), comprising an upper opening (11) that can be closed by a lid (14, 140, 540), a lateral wall region (12) and a base (13) and a hygroscopic substance (19, 190, 590, 790) contained in the interior of the sample container for drying sample material (23, 230) in the sample container, wherein the sample container is partitioned into at least two compartments, of which one is a sample compartment (16, 160, 560), and the other is a drying compartment (18, 180, 580) containing the hygroscopic substance, wherein the hygroscopic substance is connected to the interior of the sample container in a steam exchange connection, and wherein the sample compartment extends from an upper end, particularly equipped with an opening (40, 400), in the longitudinal direction to the opening in a flush manner to the base (13) of the sample container.
The invention relates to a sample container (10, 100, 500, 700) for biological sample material (23, 230), comprising an upper opening (11) that can be closed by a lid (14, 140, 540), a lateral wall region (12) and a base (13) and a hygroscopic substance (19, 190, 590, 790) contained in the interior of the sample container for drying sample material (23, 230) in the sample container, wherein the sample container is partitioned into at least two compartments, of which one is a sample compartment (16, 160, 560), and the other is a drying compartment (18, 180, 580) containing the hygroscopic substance, wherein the hygroscopic substance is connected to the interior of the sample container in a steam exchange connection, and wherein the sample compartment extends from an upper end, particularly equipped with an opening (40, 400), in the longitudinal direction to the opening in a flush manner to the base (13) of the sample container.
The present invention relates to the method for treatment of tissue samples with proteolytic/histolytic additive collagenase or other similar protease prior to testing with an antigen capture immunoassay to identify cattle infected with Bovine Viral Diarrhea Virus (BVDV). The use of collagenase or other similar protease in antigen extraction step of the assay drastically increases accuracy of the assay, thus it allows for a more effective, reliable, quick, and cost effective way of identifying and thereby removing infected cattle and/or other animals from an otherwise uninfected herd.
C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
15.
KIT AND METHOD FOR DETECTING BOVINE VIRAL DIARRHEA VIRUS IN TISSUE SAMPLES
The present invention relates to the method for treatment of tissue samples with proteolytic/histolytic additive collagenase or other similar protease prior to testing with an antigen capture immunoassay to identify cattle infected with Bovine Viral Diarrhea Virus (BVDV). The use of collagenase or other similar protease in antigen extraction step of the assay drastically increases accuracy of the assay, thus it allows for a more effective, reliable, quick, and cost effective way of identifying and thereby removing infected cattle and/or other animals from an otherwise uninfected herd.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
16.
DIAGNOSTIC COMPOSITION AND METHOD FOR THE DETECTION OF A TRICHINELLA INFECTION
A diagnostic composition to detect antibodies in a sample obtained from an animal or human being infected by Trichinella, comprising at least one peptide containing a series of amino acids that form a continuous or discontinuous epitope recognized by sera from pigs infected with Trichinella.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
C12N 9/64 - Protéinases provenant de tissu animal, p. ex. rennine
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
Method for the diagnosis of a tuberculosis infection caused by Mycobacteria belonging to the Mycobacteria tuberculosis complex group (MTC) in an animal including a human being, which comprises in vitro-detection of cell-mediated immune response to OmpAtb and/or antibodies against OmpAtb in a sample taken from that animal.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
C07K 14/35 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Mycobacteriaceae (F)
A61K 39/04 - Mycobacterium, p. ex. Mycobacterium tuberculosis
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Preparations for diagnosis and research, particularly as diagnostic tools, namely for clinical, medical and veterinary laboratory use, for use in the diagnosis of diseases and/or the detection of pathogens.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Diagnostic preparations for scientific or research use, namely test strips for detecting markers of prion diseases, especially prion protein
(2) Diagnostic preparations for clinical or laboratory use in the nature of test strips for diagnosing prion diseases.
(1) Surgical, medical and veterinary apparatus and instruments, namely, homogenization device for homogenization of tissue samples, containers for transferring tissue samples and collection of homogenates.
(2) Veterinary apparatus and instruments, namely, homogenization device for homogenization of tissue samples, containers for transferring tissue samples and collection of homogenates.
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Data collection aparatus, namely, apparatus for optical analysis of test strips. (1) Research, development, analysis, and consultation in the field of medicine, chemistry and biology.
(2) Diagnosis in the field of medicine.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Chemicals used in industry and science, namely test strips for detecting markers for prion diseases, in particular prion proteins. Test strips for diagnosing prion diseases.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Testing of animals, in particular animals for slaughter, for diseases, and for substances affecting the use of animals for foodstuffs; drawing up documents showing proof of origin of animals, in particular animals for slaughter; testing and drawing up of quality certificates and documents showing proof of origin for foodstuffs, in particular meat and meat products.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Reagents; diagnostic chemical and biological reagents for scientific, medical or veterinary research use; diagnostic and testing substances and preparations; diagnostic chemical preparations for scientific, industrial, medical or veterinary researach use; scientific or research chemicals including reagents for use in the preparation of in-vitro diagnostic kits. Pharmaceutical and veterinary preparations and substances; diagnostic preparations for medical or veterinary purposes; clinical diagnostic reagents for in-vitro use; in-vitro diagnostic kits for the detection of tuberculosis or paratuberculosis in animals; reagents, solutions, dilutents for veterinary or medical use. Diagnostic kits, in-vitro diagnostic kits; parts and fittings for all the aforesaid goods.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Diagnostic chemical and biological reagents and preparations for medical or veterinary research use; scientific or research chemicals, namely, reagents for use in the preparation of invitro diagnostic kits for veterinary use.
(2) Invitro diagnostic kits containing reagents, for use in detecting Johne's disease in bovines and ovines; reagents for veterinary use; veterinary vaccines for bovines and ovines.
