The invention relates to a medical implant having an electrical line arrangement with a longitudinal extent, comprising a sheet-like, strip-shaped planar substrate which is made of a flexible and non-elastic material and on and/or in which a number of electrical conductors are arranged, wherein along the longitudinal extent of said conductors the electrical line arrangement is mechanically and electrically connected at one end to an array that applies and/or senses signals and, at the longitudinally opposite end, to a rigid connecting structure such that it is movable with respect to the structure, wherein at least in a longitudinal portion connected at one end to the connecting structure the sheet-like, strip-shaped planar substrate of the electrical line arrangement has an undulating shape characterised by a sequence of at least one wave crest and one wave trough which extend orthogonally with respect to an otherwise flat surface of the sheet-like, strip-shaped planar substrate. The invention is characterised in that at least the longitudinal portion of the sheet-like, strip-shaped planar substrate of the electrical line arrangement which at one end is connected to the connecting structure, as well as at least part of said connecting structure, are surrounded in a fluid-tight manner by an elastic sheathing.
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
2.
INSTALLATION TOOL SET FOR PRODUCING A HEAD PART, AND METHOD FOR PRODUCING A HEAD PART USING THE INSTALLATION TOOL SET
An installation tool set for producing an implantable medical device includes an installation tool with a rod longitudinal axis and an axially extending rod surface, along which a local recess is introduced. A fixing body defines a through channel, through which the installation tool is passable along a first rod section and into which an opening opens. The opening is oriented orthogonally to the through channel, around which an internal thread is arranged within the fixing body. An adjusting rod has a joining contour that is counter-contoured relative to the local recess in the installation tool and a counter-thread engageable with the internal thread of the fixing body. A receiving structure defines a recess into which the installation tool is inserted. The fixing body, an electrically conductive contact ring, and an electrically insulating, elastically deformable seal ring are arranged coaxially and in axially serial sequence along the installation tool.
H01R 43/20 - Appareils ou procédés spécialement adaptés à la fabrication, l'assemblage, l'entretien ou la réparation de connecteurs de lignes ou de collecteurs de courant ou pour relier les conducteurs électriques pour assembler les pièces de contact avec le socle isolant, le boîtier ou le manchon ou pour les en désassembler
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
H01R 24/58 - Contacts espacés le long de l'axe longitudinal d’engagement
H01R 43/00 - Appareils ou procédés spécialement adaptés à la fabrication, l'assemblage, l'entretien ou la réparation de connecteurs de lignes ou de collecteurs de courant ou pour relier les conducteurs électriques
A medical implant forms a sleeve for arranging about a nerve fiber bundle. The sleeve has a film-like substrate with a first section that converts into a hollow-cylindrical shape. A first end of the first section rests against a first surface of the first section in the wound state. The first surface faces an area enclosed by the wound first section. A second end lies opposite the first end and in the wound state is arranged laterally to a second surface of the first section. The second surface faces away from the first surface and from the radially enclosed area. An area of the first section end is monolithically connected with a second section, which in the wound state is adjacent to the second surface of the first section. The first and second sections have the set shape, with a winding direction oriented oppositely relative to the first end.
An implantable electrical contact arrangement has at least one electrode element arrangement enclosed entirely by biocompatible, electrically insulating material, and an electrode surface that is directly or indirectly enclosed by the biocompatible, electrically insulating material, the electrode element arrangement having a stack-shaped layer composite which has a metallization layer at least on a ceramic substrate over an adhesion promoter layer. The layer composite is bonded to a passivation layer such that covalent bonds are formed, and is otherwise completely encased by the passivation layer, except for at least one surface area of a metallization layer facing away from the layer composite. The passivation layer has a surface facing away from the layer composite and to which the biocompatible, electrically insulating material is directly or indirectly adjacent. The passivation layer is deposited on the layer composite by plasma-enhanced chemical vapor deposition, physical vapor deposition, or wet chemical coating.
VcVcVc) is applied. The gate contacts of the centrally arranged transistor pair are each connected to that connection contact (Vin, Vout) which is opposite the respective transistor of the transistor pair relative to the contact point. The NMOS transistors (MNc, MNd) of the 2 n transistors (MNa, MNb, MNc, MNd) connected in series, said transistors adjoining the centrally arranged NMOS transistor pair on both sides, each have a gate contact connected to the supply voltage VC and a substrate connection connected to the negative supply voltage (VSS). Finally, the PMOS transistor (MP) is assigned an arrangement of 2 n PMOS transistors (MPa, Mpb, MPc, MPd), which is inversely symmetrical with respect to the above-mentioned transistor arrangement, and a further PMOS transistor (MPe).
H03K 17/06 - Modifications pour assurer un état complètement conducteur
H03K 17/687 - Commutation ou ouverture de porte électronique, c.-à-d. par d'autres moyens que la fermeture et l'ouverture de contacts caractérisée par l'utilisation de composants spécifiés par l'utilisation, comme éléments actifs, de dispositifs à semi-conducteurs les dispositifs étant des transistors à effet de champ
6.
ELECTRICAL CIRCUIT ARRANGEMENT HAVING A TRANSISTOR-BASED SWITCH, AND METHOD FOR SWITCHING THE TRANSISTOR-BASED SWITCH
Proposed is an electrical circuit arrangement having an input contact (in) which is switchably connected via two series-connected transistors (T1, T2) to an output contact (out), wherein source contacts respectively assigned to the two transistors are interconnected, and gate contacts respectively assigned to the two transistors are interconnected, and the source and gate contacts of the two transistors are connected, with the ability to be switched on and off, to at least one current source (I) that is suitably designed to generate at the two transistors a source/gate voltage (Vgs_1, 2) that is higher than the respectively associated threshold voltages of the transistors. Furthermore, the source and gate contacts of the two transistors can be connected to a circuit unit (T4, T5, D5) which is suitably designed to equalize the gate voltage and the source voltage of each of the two transistors as soon as the current source is disconnected from the source and gate contacts of the two transistors. Also proposed is a method for switching the transistor-based switch. The electrical circuit arrangement is distinguished by the fact that the current source is connected to a high-voltage supply voltage (HV) and can be connected via an ON/OFF switching functional unit (SE) to a functional unit (T_D1), which is connected in series and causes a voltage drop, and to a source-drain path of a third transistor (T3), which is connected to a low-voltage supply voltage (LV), and by the fact that the gate contacts of the two transistors are connected via the ON/OFF switching functional unit (SE) to the current source (I), and the source contacts of the two transistors are connected to the gate contact of the third transistor (T3).
H03K 17/687 - Commutation ou ouverture de porte électronique, c.-à-d. par d'autres moyens que la fermeture et l'ouverture de contacts caractérisée par l'utilisation de composants spécifiés par l'utilisation, comme éléments actifs, de dispositifs à semi-conducteurs les dispositifs étant des transistors à effet de champ
H03K 17/10 - Modifications pour augmenter la tension commutée maximale admissible
The invention relates to a medical implant having an electrode arrangement configured as a wound cuff, or cuff electrode, suitable for extravascular or extraneuronal fastening along an intracorporeal vessel or a nerve fibre bundle, and having an electrical feed and output arrangement, available over a longitudinal extent, which electrically connects the cuff electrode to an implantable supply unit designed separately from the cuff electrode, wherein the electrical feed and output arrangement, along a section of its longitudinal extent, is surrounded by an elastic casing which fixedly connects the electrical feed and output arrangement to an intracorporeal tissue region via a fastening means that can be operatively connected to the elastic casing. The invention is characterized in that the elastic casing has a longitudinal extent and a circumferential edge oriented radially about the longitudinal extent, and in that at least one tunnel-like opening contour is arranged at the circumferential edge of the casing, along at least a transverse plane oriented orthogonally to its longitudinal extent, which opening contour is suitable for allowing the fastening means, designed as a medical thread, to pass locally therethrough and has no structural components projecting radially beyond the circumferential edge of the casing.
The invention relates to a sleeve-shaped medical implant which has a film-like, flexible planar substrate which, by means of material-inherent impressed shaping, automatically adopts, without application of external force, the form of a straight cylinder, in which the planar substrate provides a cylinder interior surface which, in the implanted state, is able to form an extravascular or extraneuronal surface contact along an intracorporeal strand-like structure in the form of an intracorporeal vessel or a nerve fibre bundle. The invention is characterized in that the film-like, flexible planar substrate has two edge regions which, in the implanted state, lie opposite each other along a cylinder axis assigned to the straight cylinder form, and in that the edge regions are each limited by an undulating edge contour line.
The invention relates to a medical implant which has a film-like, flexible planar substrate in which material-inherent, shape-determining restoring forces are impressed which shape the film-like, flexible planar substrate, without application of external force, into a straight-cylindrical wound sleeve in such a way that, after formation of a first complete wound layer, the latter is wrapped around by at least one further wound layer, at least in the form of a partial winding. The invention is characterized in that at least one locally limited pattern of a first type is applied to the film-like, flexible planar substrate in the region of the first wound layer, and at least one locally limited pattern of a second type is applied thereto in the region of the at least one further wound layer, and in that the at least one locally limited pattern of the first type and that of the second type are applied to the film-like, flexible planar substrate in such a way that they are visually perceptible radially from the outside.
The invention relates to a medical implantable arrangement in the form of a wrap cuff for applying electrical signals along an intracorporeal vessel or a nerve fibre bundle. The invention is characterised in that: at least 2·n electrodes, where n ≥ 2, are arranged in serial spatial succession along at least one virtual line on a support structure and are wired to a current generator; the current generator supplies the 2·n electrodes with high-frequency stimulation signals in such a way that a first group of n electrodes is supplied with high-frequency stimulation signals of the same polarity, while simultaneously a second group of n electrodes is supplied with high-frequency stimulation signals of opposite polarity to the first group; the electrodes of the first and second groups are each arranged in an alternating sequence along the virtual line; and the at least one virtual line, along which the at least 2·n electrodes are arranged in serial spatial succession, has one of the following shapes and arrangements: - straight and parallel to a wrap-around longitudinal axis (8) that can be associated with the wrap cuff, - straight and inclined to a wrap-around longitudinal axis (8) that can be associated with the wrap cuff, - wave-shaped with a wave baseline (9) that is orientated parallel to a wrap-around longitudinal axis (8) that can be associated with the wrap cuff, - wave-shaped with a wave baseline (9) that is orientated inclined to a wrap-around longitudinal axis (8) that can be associated with the wrap cuff.
The invention relates to a mobile electrical charging system which can be placed on a person, at least for supplying electrical energy to an implant which is located intracorporeally in the region of the upper body of the person and which has an electrical energy store, wherein the charging system comprises at least two spatially separated components, of which a first component is in the form of a contactless energy transmission unit and a second component is in the form of an electrical energy source and control unit, and the first component is or can be connected to a fastening assembly which can be fixed on the upper body of the person in such a way that the first component can be arranged in an orientation and position which can be specified relative to the person, and the second component is or can be wired to the first component.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
16 - Papier, carton et produits en ces matières
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
Produits et services
Substances for laboratory use; Substances [chemical] for electrical insulation for use in electric switches; Polyamides; Polyamides; Polyamides; High purity polyamides. Polymer modelling clay. Electrical insulators; Insulating films; Plastic film for insulating purposes; Plastic films for electronic insulation; Insulating varnish; Insulating materials produced from plastics; Insulating materials for electrical purposes; Insulating materials; Insulating materials produced from plastics; Dielectrics [insulators]; Electrical insulators; Insulation for electric conductors; Insulators for electric mains; Insulation articles for use on splices of electric cables; Insulating materials produced from plastics. Encapsulation of semi-conductors.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Analytical and medical diagnostic apparatus for medical purposes for neurostimulation; treatment apparatus for medical purposes, namely, implantable neurostimulators for treating chronic diseases associated with autonomous vital functions; medical electrodes and active medical implants made of artificial materials for treating chronic diseases associated with autonomous vital functions for use in neurotechnology; medical electrodes and active medical implants made of artificial materials for treating chronic diseases associated with autonomous vital functions for vagus nerve recording and stimulation; active medical implants made of artificial materials for treating chronic diseases associated with autonomous vital functions for vagus nerve and baroreflex recording and stimulation primarily composed of medical electrodes, namely, foil electrodes for medical use, and electronic control and evaluation units each comprised of an implantable pulse generator connected to one or more cuff electrode arrangements for controlling the vagus nerve stimulation and evaluating signals measured in connection with the vagus nerves function, all being supplied with energy by means of inductive procedures or energy harvesting, and communicating with extracorporeal units by means of digital radio signals or optical signals, and additional incorporated mechanical sensors and actuators; accessories for the aforementioned medical instruments, electrodes, and implants, namely, telemetry devices and systems for medical applications comprised of wireless receivers and wireless transmitters allowing medical personnel and patients to receive and transmit information from and to the medical implants, to personalize functions, and patient monitoring devices and systems and sensors comprised of one or more cuff electrode arrangements, an implantable pulse generator, and electronic control units for use in measuring, reading, storing, analyzing, and controlling medical implants, to transmit vital signs and information relevant to medical conditions of the patient, namely, movement, pressure, temperature, x-ray, electromagnetic radiation and light, and to read, store, analyze and transmit data from and to the telemetry devices Science and technology services in the field of neuroscience and neurotechnology, namely, scientific research and development of medical instruments, electrodes, and implants for vagus nerve and baroreflex recording and stimulation, and development and medical research analysis of intracorporal blood-pressure sensors in the nature of ultrasound-based sensors Medical services, medical and clinical treatment services, namely, vagus nerve and baroreflex recording and stimulation using electrical power; therapeutic services in the nature of vagus nerve and baroflex stimulation for the treatment of high blood pressure
14.
ELECTRIC CIRCUIT ARRANGEMENT FOR A BIOMEDICAL INTERFACE
The invention relates to an electric circuit arrangement for a biomedical interface, having electric contacts of which a number n of electric contacts are used for contacting at least one implantable electrode arrangement which can be attached to an organic structure, and having at least one electric function block which is electrically connected to at least one of the n electric contacts. The invention is characterised in that the at least one electric function block has function elements implemented by means of SOI technology, and that the at least one electric function block can be operated at a supply voltage to which an electric average potential can be assigned, which supply voltage corresponds to an electric potential which can be assigned to the organic structure.
A61N 1/02 - ÉlectrothérapieCircuits à cet effet Parties constitutives
A61N 1/08 - Aménagements ou circuits de surveillance, de protection, de commande ou d'indication
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
15.
LEVEL-INCREASING SWITCHING ARRANGEMENT WITH A CHARGE PUMP
The invention relates to an electric switching arrangement having a charge pump (NCP) which has at least two connection contacts (a1, a2), of which a first connection contact (a1) is connected to a first voltage potential (V1) and a second connection contact (a2) is connected via a series circuit, which has at least one first capacitor (C1), a second capacitor (C2) and a first diode (D1) arranged between the two capacitors, to a second voltage potential (V1) which is higher than the first voltage potential (V1) and which is also connected, via a switching element, to the first capacitor (C1), wherein the charge pump (NCP) has a third connection contact (a3), which is connected to an output (AK1) of a first comparator (K1) which has a first and a second comparator input (K1-, K1+), of which the first comparator input (K1-) is connected to an anode potential (refP) of a second diode (D2) at which the second voltage potential (V2) is applied and which is connected in series to the first diode (D1) and in parallel to the second capacitor (C2), and of which the second comparator input (K1+) is connected to a cathode potential (refN) of a third diode (D3) at the allocated anode of which the second voltage potential (V2) is applied.
H02M 3/07 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des résistances ou des capacités, p. ex. diviseur de tension utilisant des capacités chargées et déchargées alternativement par des dispositifs à semi-conducteurs avec électrode de commande
H02M 1/00 - Détails d'appareils pour transformation
H02M 1/32 - Moyens pour protéger les convertisseurs autrement que par mise hors circuit automatique
16.
ELECTRIC SWITCHING ARRANGEMENT FOR LEVEL CONVERSION OF DIGITAL SIGNALS
The invention relates to an electric switching arrangement for level conversion of digital input signals of a first voltage domain into digital output signals of a second voltage domain with respect to the first voltage domain, having a first transistor which is controlled by the digital input signal and whose assigned source-drain section is connected between a ground potential and an input of a current mirror which has an output that is connected to an intermediate store via a first contact point. The invention is characterised in that the intermediate store has a second contact point which is connected to a gate terminal of a second transistor whose assigned source-drain section is arranged in series with the source-drain section of the first transistor between the input of the current mirror and the first transistor.
in thatin that the gate terminal of the fourth transistor is connected in a switchable manner to at least one constantly specifiable voltage potential.
H03F 1/22 - Modifications des amplificateurs pour réduire l'influence défavorable de l'impédance interne des éléments amplificateurs par utilisation de couplage dit "cascode", c.-à-d. étage avec cathode ou émetteur à la masse suivi d'un étage avec grille ou base à la masse respectivement
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
The invention relates to an installation tool set for producing a head part of an implantable medical device, comprising a head part housing that can be made of a curable and pourable material and has a blind hole-type recess, along which at least one electrically conductive contact ring element and an electrically insulating and elastically deformable seal ring are joined against each other in a force-fitting manner under the effect of an axial joining force in a coaxial arrangement and in an axially serial sequence, wherein the installation tool set comprises means for fixing the axial position of a fixing body along the installation tool.
H01R 43/00 - Appareils ou procédés spécialement adaptés à la fabrication, l'assemblage, l'entretien ou la réparation de connecteurs de lignes ou de collecteurs de courant ou pour relier les conducteurs électriques
H01R 43/20 - Appareils ou procédés spécialement adaptés à la fabrication, l'assemblage, l'entretien ou la réparation de connecteurs de lignes ou de collecteurs de courant ou pour relier les conducteurs électriques pour assembler les pièces de contact avec le socle isolant, le boîtier ou le manchon ou pour les en désassembler
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
H01R 24/58 - Contacts espacés le long de l'axe longitudinal d’engagement
19.
Device and Method for Detecting a Medically Active Implant Within a Person
The invention is a device and a method for detecting a medically active implant capable of electrical stimulation implanted within a person. Moreover, the invention also relates to the use of the device for determining the operational status of the medically active implant. The device is characterized by components: a) at least two electrodes that are in, or can be brought into, contact with the person, b) an electrical voltage measuring unit which is electrically connected to the at least two electrodes and which is capable of generating electrical voltage timing signals and c) an evaluation unit which is connected to the electrical voltage measuring unit.
The invention relates to an implantable electrical contact arrangement which has at least one electrode element arrangement enclosed entirely by biocompatible, electrically insulating material and comprising at least one electrode surface that is directly or indirectly enclosed by the biocompatible, electrically insulating material, the electrode element arrangement having a stack-shaped layer composite which has a metallisation layer at least on a ceramic substrate over an adhesion promoter layer. The invention is characterised in that: the stack-shaped layer composite is bonded to a passivation layer such that covalent bonds are formed, and is otherwise completely encased by said passivation layer, except for at least one surface area of the metallisation layer facing away from the layer composite; the passivation layer has a passivation layer surface which faces away from the stack-shaped layer composite and to which the biocompatible, electrically insulating material is directly or indirectly adjacent; and the passivation layer is deposited on the stack-shaped layer composite by means of plasma-enhanced chemical vapour deposition (PECVD), physical vapour deposition (PVD), or wet chemical coating.
The invention relates to a medical implant in the form of a wrap sleeve for arranging about a nerve fiber bundle, comprising a flat biocompatible film-like substrate with at least one first flat substrate section that can be converted into a hollow cylindrical shape by means of a winding process in a winding direction, which is specified by a set shape that is inherent to the material, about a spatial axis and has a first flat substrate section end which rests against a first surface of the first flat substrate section in the wound state, said surface being oriented so as to face an area radially enclosed by the wound first flat substrate section, and a second flat substrate section end, which lies opposite the first flat substrate section end and is arranged laterally to a second surface of the first flat substrate section, said second surface facing away from the first surface, in the wound state, said second surface being oriented so as to face away from the area radially enclosed by the wound first flat substrate section. At least one region of the first flat substrate section end is monolithically connected to a second flat substrate section which rests against the second surface of the first flat substrate section in the wound state. The invention is characterized in that each of the first and second flat substrate sections has the set shape which is inherent to the material with a respective winding direction which is oriented opposite the first flat substrate section end.
An implantable electrode arrangement provides spatially-selective detection of neuronal electrical signals, which propagate along at least one nerve fiber contained in a nerve fascicle, and for selective electrical stimulation of the at least one nerve fiber, comprising a biocompatible carrier substrate, which has at least one carrier substrate region that can be placed around the nerve fascicle in a cuff and has a straight cylinder-shaped carrier substrate surface which faces the nerve fascicle in the implanted state. The carrier substrate surface has an axial extension and an extension oriented circumferentially in a direction and a first electrode arrangement attached thereto. The electrode arrangement comprises in an axial sequence, at least three first electrode structures with at least two first electrode surfaces arranged in the circumferentially, and at least two spaced first electrode strips, displayed in the axial direction which extend circumferentially which are in a ring shape, which encloses the at least three electrode structures on both sides in the axial direction. The electrodes are connectable or are connected to a signal detector and generator.
A medical handling which connects two implants arranged spatially separated from each other, by a flexible connecting line, along which a mechanical interface forms a plug-socket connection. The handling set comprises a tube and a mandrin which is internally guided therein and provides a mandrin tip, fixedly attached to a distal mandrin region which is a releasable first joint. In the joined state the handling set projects beyond the distal tube end. A first joining contour, which is part of a second joint, as well as an adapter element with a counter joining contour which is contoured counter to the first joint forms a second join, and a second joining contour contoured counter to the plug or socket of the mechanical interface which is part of a third joint.
The invention is a head part of an implantable device, method of production thereof and a plug which can be fitted into the head part. The head part comprises a housing which has at least one blind hole plug contact socket with a socket opening as well as a socket base axially opposite the socket opening, along which at least one electrically conductive contact ring element and an electrically insulating, elastically deformable sealing ring, which are enclosed by a solidified casting compound, are joined together coaxially axially. Arranged within the head part is at least one second blind hole plug contact socket with a socket opening as a socket base axially opposite the socket opening, along which at least one electrically conductive contact ring element and an electrically insulating, elastically deformable sealing ring is located, which are enclosed by the solidified casting compound, are joined together in a coaxial arrangement and in an axially serial sequence.
The invention pertains to a head part of an implantable device, its method of production and a plug assembly which can be fitted into the head part. The head part comprises a head part housing which has at least one blind hole plug contact socket with a socket opening and a socket base axially opposite the socket opening, along which at least one electrically conductive contact ring element and an electrically insulating, elastically deformable seal ring is positioned and which are enclosed by a solidified casting compound, are joined together in a coaxial arrangement and in an axially serial sequence.
The invention is an assembly for checking the functionality of a measuring object, that is a DUT, in a medical implant or at least one part of the medical implant. The assembly comprises a test signal generator, a test module that is connected to the test signal generator. The assembly has a first receiving structure with at least one contact electrode, into which an adapter rigidly connects to the DUT in a releasable manner which is inserted to form least one electrical contact. A control and analysis unit is connected to the test signal generator and to the test module in a wired or wireless manner.
An implantable electrical contact arrangement comprising at least one electrode element entirely integrated into a carrier substrate of a biocompatible, electrically insulating material, and at least one freely accessible electrode surface enclosed by the biocompatible, electrically insulating carrier substrate. Within at least one space of the carrier substrate, which does not contain an electrode element, the carrier substrate surrounds at least one space containing at least one material with a modulus of elasticity differing from a modulus of elasticity of the material of the carrier substrate.
A method for the production of a medical implant, comprising a head section, which has at least one blind hole-type recess of an electrical plug-in contact socket, along which is arranged at least one electrically conductive contact element, together with a supply section, which is fixedly connected to the head section, and which comprises at least one electrical component, which is one of at least one microcontroller, and an electrical energy source, which are electrically connected to the at least one electrically conductive contact by way of at least one electrical conductor.
B29C 70/88 - Façonnage de matières composites, c.-à-d. de matières plastiques comprenant des renforcements, des matières de remplissage ou des parties préformées, p. ex. des inserts caractérisées principalement par des propriétés spécifiques, p. ex. électriquement conductrices ou renforcées localement
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
B29C 45/14 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet en incorporant des parties ou des couches préformées, p. ex. moulage par injection autour d'inserts ou sur des objets à recouvrir
B29C 70/72 - Enrobage d'inserts avec une partie non enrobée, p. ex. extrémités ou parties terminales de composants électriques
The invention relates to a medical handling set for connecting two implants, which are spatially separated from each other, by means of a flexible connecting line, along which a mechanical interface like a plug-socket connection is provided. The handling set comprises a tube and a mandrin, which is internally guided in the tube and provides a mandrin tip, which mandrin tip is releasably fixedly attached to the distal mandrin region by means of a first joint and, in the joined state, protrudes beyond the distal tube end; - a first joining contour provided on the distal mandrin region, which first joining contour is part of a second joint; and - an adapter element having a counter joining contour for forming the second joint, which counter joining contour is contoured counter to the first joining contour, and having a second joining contour, which is contoured counter to the plug part or socket part of the mechanical interface and is part of a third joint.
The invention relates to a medical handling set for connecting two implants, which are spatially separated from each other, by means of a flexible connecting line, along which a mechanical interface like a plug-socket connection is provided. The handling set comprises a tube and a mandrin, which is internally guided in the tube and provides a mandrin tip, which mandrin tip is releasably fixedly attached to the distal mandrin region by means of a first joint and, in the joined state, protrudes beyond the distal tube end; - a first joining contour provided on the distal mandrin region, which first joining contour is part of a second joint; and - an adapter element having a counter joining contour for forming the second joint, which counter joining contour is contoured counter to the first joining contour, and having a second joining contour, which is contoured counter to the plug part or socket part of the mechanical interface and is part of a third joint.
The invention relates to a head part for an implantable medical device, to a method for producing same, and to a plug assembly which can be fitted into the head part. The head part has a head part housing that has at least one blind hole-type plug contact socket which comprises a socket opening and a socket base lying axially opposite the socket opening and along which at least one electrically conductive contact ring element and an electrically insulating, elastically deformable seal ring are joined together in a coaxial arrangement and in an axially serial sequence, said contact ring element and seal ring being enclosed by a solidified casting compound. The invention is characterized in that the head part is equipped with at least one second blind hole-type plug contact socket which comprises a socket opening and a socket base lying axially opposite the socket opening and along which at least one electrically conductive contact ring element and an electrically insulating, elastically deformable seal ring are joined together in a coaxial arrangement and in an axially serial sequence, said contact ring element and seal ring being enclosed by a solidified casting compound; the socket base of each plug contact socket is delimited by a connection means at least partly enclosed by the solidified casting compound; and the connection means encloses a through-channel which opens into the blind hole-type plug contact sockets at both sides.
The invention relates to a head part of an implantable medical device, to a method for producing same, and to a plug assembly which can be fitted into the head part. The head part has a head part housing which has at least one blind hole-type plug contact socket with a socket opening and a socket base lying axially opposite the socket opening, wherein at least one electrically conductive contact ring element and an electrically insulating and elastically deformable seal ring, which are enclosed by a solidified casting compound, are joined together along the plug contact socket in a coaxial arrangement and in an axially serial sequence. The invention is characterized in that the socket base is delimited by a connection means, said connection means being at least partly enclosed by the solidified casting compound and being attached to at least one media channel, which opens into the blind hole-type plug contact socket and is at least partly enclosed by the solidified casting compound and which has one channel end that faces away from the connection means and is connected to a media source. The at least one media channel is designed in the form of a fluid line, and the media source is a fluid pump which is connected to a fluid reservoir. The plug assembly has a plug body in an adapted manner to the media channel, said plug body comprising at least one inner hollow channel, one side of which leads to the distal plug body end. Additionally, the distal plug body end has a joint contour that ensures a flush joint between the hollow channel and the media channel, which opens into the blind hole-type plug contact socket, when the plug assembly is fitted within the plug contact socket.
The invention is a medical implant which is a wrap-around cuff comprising a flexible, biocompatible, film carrier substrate, that has a carrier substrate region which is wrapped around a wrap axis to form a tube. The invention has a protective structure directly or indirectly attached to the carrier substrate, which can be transformed from a first, open state into a second closed state that encloses the carrier substrate region that is wrapped to form a tube at least axially around a wrapping axis extending in the peripheral direction of the tube.
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A device is described for the transcutaneous location of an intracorporeally, subcutaneously located medical implant, which has an implant surface on which at least one electrical coil is arranged. The coil has at least one coil winding enclosing a region of the implant surface, together with an extracorporeally operable unit, to which at least one electrical coil is fitted, which is adapted in shape and size to the electrical coil arranged on the implant, and which is connected to an electrical control unit and to a signalling means, which generates a perceptible signal, at least in the case of maximum inductive coupling between the two electrical coils.
2 s, and in the second state has an effective operating surface that is flexibly deformable and at least partially reflects ultrasonic waves. Ultrasonic waves are generated by a sonographic device and which strike an effective operating surface of the intracorporeally applied medical implant and are partially reflected for detecting changes in the spatial distance between the operating surface and the sonography device.
A61B 90/98 - Moyens d’identification pour les patients ou les instruments, p. ex. étiquettes utilisant des moyens électromagnétiques, p. ex. transpondeurs
G06K 7/10 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire
G06K 19/07 - Supports d'enregistrement avec des marques conductrices, des circuits imprimés ou des éléments de circuit à semi-conducteurs, p. ex. cartes d'identité ou cartes de crédit avec des puces à circuit intégré
A device for the extravasal or extraneuronal fastening of a medical implant has a biocompatible surface substrate including a first substrate portion which is a compression sleeve and a free end portion. By winding the first substrate portion about a spatial axis, the axis is loosely radially covered in at least one layer by the wound first substrate portion. A second substrate portion, which is attached integrally to the first substrate portion which is not wound about the spatial axis, has a connection extending away from the medical implant.
The invention relates to a device and a method for detecting a medically active implant, capable of electrical stimulation, implanted within a person. The invention further describes a use of the device for determining the operating status of the medically active implant. The device is characterised by the following components: a) at least two electrodes which are in, or can be brought into, electrical contact with the patient; b) an electrical voltage measurement device, which is electrically connected to the at least two electrodes and is capable of generating electrical voltage timing signals; and c) an evaluation unit connected to the electrical voltage measurement device, comprising the following components: a unit for determining a power density spectrum based on the electrical voltage timing signals measured between the at least two electrodes, a unit for determining local maxima within the power density spectrum and the peak frequency allocated to each, a unit for determining a lowest common denominator of the peak frequencies determined, a comparator unit, which runs a data comparison on the basis of the lowest common denominator determined, which corresponds to a stimulation frequency of the medically active implant, and information stored in a reference database and generates a comparison outcome, and a signal unit which is in communication with the comparator unit and generates a signal as a function of the comparison outcome.
The invention relates to an assembly for checking the functionality of a measuring object, i.e., DUT, in the form of a medical implant or at least one part of a medical implant. The assembly comprises a test signal generator; a test module that is connected to the test signal generator and has a first receiving structure with at least one contact electrode, an adapter module rigidly connected to the DUT in a releasable manner being insertable into said receiving structure, thereby forming at least one electric contact; and a control and analysis unit which is directly or indirectly connected to the test signal generator and the test module in a wireless or wired manner.
The invention has a contact assembly including a spatial longitudinal extension which is orientated parallel to the winding axis. The contact assembly is fixedly joined to the carrier substrate along a joining region which has a joining region length orientated in parallel to the winding axis. The orthogonal projection relative to the winding axis overlaps with a first region of the carrier substrate which is wound into a tube.
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
42.
Method for producing a head part of an implantable medical device
A method for producing a head part of an implantable medical device is described, with a head part housing, which has a recess in the form of a blind hole, along which at least one electrically conducting contact ring element, together with an electrically insulating, elastically deformable sealing ring, are joined together in a force fit in a coaxial arrangement and an axial serial sequence under an axial joining force. The method is characterized in that the generation of the joining force between the at least one contact ring element and the sealing ring is executed along the assembly tool by use of means of attachment fitted on both sides of the at least one contact ring element and the sealing ring along the assembly tool, of which at least one means of attachment is axially movably and detachably fixed in an axially secure manner to the assembly tool.
B29C 39/10 - Moulage par coulée, c.-à-d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulageAppareils à cet effet pour la fabrication d'objets de longueur définie, c.-à-d. d'objets séparés en incorporant des parties ou des couches préformées, p. ex. coulée autour d'inserts ou sur des objets à recouvrir
H01R 13/52 - Boîtiers protégés contre la poussière, les projections, les éclaboussures, l'eau ou les flammes
H01R 24/58 - Contacts espacés le long de l'axe longitudinal d’engagement
The invention relates to an implantable electrical contact arrangement which has at least one electrode element arrangement otherwise entirely integrated into a carrier substrate produced of a biocompatible, electrically insulating material, and at least one freely accessible electrode surface enclosed directly or indirectly by the biocompatible, electrically insulating material. The invention is characterized in that, within a sub-space that does not contain the at least one electrode element arrangement, the carrier substrate completely encompasses at least one space containing at least one material having a modulus of elasticity different from the modulus of elasticity associated with the material of the carrier substrate.
The invention relates to a method for producing a medical implant, which comprises: a head part having least one blind-hole-like recess in the form of a electrical contact socket, along which socket at least one electrically conductive contact element is arranged; and a supply part fixedly connected to the head part, which supply part comprises at least one electrical component, preferably in the form of a microcontroller and/or an electrical energy source, which is electrically connected to the at least one electrically conductive contact element via at least one electrical conductor structure. The method is characterised by the following method steps: - producing a fixing plate made of a curable casting compound and having a top side and a bottom side, in which fixing plate the at least one electrical conductor structure is fixed and protrudes through the top side and bottom side of the plate, - arranging the fixing plate in a casting mould such that the bottom side of the plate forms a partial surface of the casting mould, - electrically contacting the at least one electrical conductor structure to the at least one electrical component before or after the fixing plate is arranged as the partial surface partially delimiting the casting mould, and - producing the supply part by encapsulating the at least one microcontroller, the electrical energy source and the at least one electrical conductor structure protruding from the bottom side of the plate, by means of the curable casting compound, forming an integrally bonded connection to the bottom side of the fixing plate.
The invention is an implantable electrical connection between an electrical implant which has at least one electrical conductor and at least one electrical feed line. The invention further relates to a method for producing an implantable electrical connection between an electrical implant. The invention comprises at least one electrical cable having a cable end, to which an electrically conductive flat piece is unsupportedly fined, and that the at least one implant-side electrical conductor is joined to the flat piece.
An implantable assembly is described for acquisition of neuronal electrical signals at a selected location which propagate along at least one nerve fiber contained in a nerve fiber bundle, as well as for selective electrical stimulation of the at least one nerve fiber, having: an implantable electrode assembly (E) which is disposed on a biocompatible support substrate which can be positioned around the nerve fiber bundle in a cuff. The cuff has a cylindrical support substrate surface (i) which in the implanted condition is orientated facing the nerve fiber bundle, on which a first electrode assembly for locationally selective acquisition of the neuronal electrical signals and selective electrical stimulation of the at least one nerve fiber, and on which a second electrode assembly is disposed to record an ECG signal, and an analysis and control unit (A/S) which can be electrically conductively connected or is connected to the implantable electrode assembly (E), in which the locationally selective acquired neuronal electrical signals as well as the ECG signal can be analyzed in a time-resolved manner such that a neuronal time signal correlated with a physiological parameter, such as blood pressure, can be derived.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
The invention relates to a medical implant of the type of a wrap-around cuff electrode assembly, cuff electrode for short, which comprises a flexible, biocompatible, film-like carrier substrate that has a carrier substrate region which takes a tubular shape by wrapping around a wrap axis. The invention is characterized in that a protective structure is applied directly or indirectly to the carrier substrate and that can be transferred from a first, open state to a second, closed state in which it encloses the carrier substrate, which is wrapped up to a tubular structure, at least in some parts axially to the wrap axis and completely in the peripheral direction of the tubular structure.
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
The invention relates to a device for the transcutaneous location of an intracorporeally, subcutaneously located medical implant having an implant surface on which at least one electrical coil is arranged, said coil comprising at least one coil winding surrounding a region of the implant surface, with an extracorporeally operable unit on which a plurality of electrical coils are attached, said plurality of electrical coils being adapted in shape and size to the electrical coil arranged on the implant and being connected to an electrical control unit, and a signalling means which produces a perceptible signal at least in the event of a maximum inductive coupling between one of the external coils and the implant coil.
The invention relates to a medical implant with a structure which is made of at least one biocompatible material, can be converted from a first spatially compact state into a second spatially deployed and flexibly deformable state, has a modulus of elasticity that corresponds to the wall of a blood vessel in an order of magnitude ranging from 105N m-2to 107N m-2, has at least one region with an acoustic impedance of more than 1.63·106kg/m2s, and in the second state has an effective operating surface that is flexibly deformable and at least partly reflects ultrasonic waves. The invention additionally relates to an assembly for detecting an intracorporeal movement pattern using the medical implant that has a sonographic device that is positioned extracorporeally such that ultrasonic waves which are generated by the sonographic device and which strike the effective operating surface of the intracorporeally applied medical implant and are partly reflected thereon can be used to detect changes in the spatial distance between the effective operating surface and the sonographic device.
A device is described for extravascular or extraneuronal fastening of a medical implant, with a biocompatible surface substrate having a first substrate portion, which is configured in the manner of a compression sleeve and has a free end portion which, by winding the first substrate portion about a spatial axis, is loosely radially covered at least in one layer by the wound first substrate portion, and also a second substrate portion, which is attached integrally to the first substrate portion, is not wound about the spatial axis and is connectable directly or indirectly to a connection structure leading away from the medical implant. The invention is characterized in that, in the region of the end portion, at least one means is applied which, when the first substrate portion is in the wound state about the spatial axis, forms a join with the first substrate portion and/or the second substrate portion.
The invention relates to an implantable electromechanical plug connector, comprising a plug part and a socket part, said plug part having at least one joining portion, which joining portion has at least one electrically insulating surface, which has at least at least one electrode body having a freely accessible electrode surface, and which joining portion can be completely inserted into an insertion opening within the socket part by insertion parallel to the electrically insulating surface, which insertion opening is open at one end, and said socket part having, within the insertion opening open at one end, an electrically insulating wall portion, which laterally delimits the insertion opening at least in parts and the surface of which provides at least one counter electrode body having a freely accessible counter electrode surface, wherein, when the joining portion of the plug part is completely inserted in the insertion opening, the electrically insulating wall portion is oriented facing the electrically insulating surface of the joining portion of the plug part in such a way that the counter electrode surface touches the electrode surface. The invention is characterized in that an element separate from the plug part and the socket part is provided, and that, when the joining portion of the plug part is completely inserted in the insertion opening, the element can be inserted into the socket part or into a region between the plug part and the socket part and releasably locked to the socket part in such a way that the element increases at least one contact pressure force between the at least one touching counter electrode surface and the electrode surface.
An implantable electrical contact arrangement is described which has at least one electrode body arrangement composed otherwise entirely of biocompatible, electrically insulating material, with at least one freely accessible electrode surface enclosed directly or indirectly by the biocompatible electrically insulating material. The invention is characterized in that the electrode body arrangement has a stack-shaped layer composite which provides at least one gold layer connected to an iridium layer via a diffusion barrier layer. The stack-shaped layer composite by being completely encapsulated by an SiC layer, with the exception of at least one surface region of the iridium layer facing to be directed away from the layer composite. The SiC layer has an SiC layer surface which is facing to be directed away from the stack-shaped layer composite and which is adjoined directly or indirectly by the biocompatible, electrically insulating material.
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
53.
Implantable electric multi-pole connection structure
The invention relates to an implantable electric multi-pole connection between an electric implant and an electric feed and discharge structure. The invention is characterised in that a flexible, film-like, electrically non-conductive, strip-shaped surface element is arranged between the implant and the feed and discharge structure. The surface element comprises at least one first surface, on which a number of electrodes n greater than of equal to two is arranged, which are respectively connected to the electric implant by means of electric connection conductors extending at least in parts inside the surface element. The electric feed and discharge structure comprises at least n lines which are electrically insulated from each other and which are electrically connected to one of the n electrodes. The strip-shaped surface element is wound around a winding axis, which adopts the shape of a helix, along a cover surface of a virtual cylinder provided with a cylinder axis which is straight or curved at least in sections.
A61B 5/24 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
54.
IMPLANT IN THE FORM OF A WOUND CUFF ELECTRODE ASSEMBLY
The invention relates to a medical implant in the form of a wound cuff electrode assembly, referred to as a cuff electrode for short, which comprises a flexible, biocompatible, film-like carrier substrate, which in a first region assumes the form of a tube with a tube length by being wound about a winding axis, the tube comprising a straight, cylindrical cavity which is delimited radially relative to the winding axis by a surface of the carrier substrate on which the at least one electrode surface is mounted, which is connected via at least one electrical line integrated within the carrier substrate to a non-flexible contact assembly, on which the electrical line is connected to an electrical feed and/or discharge line which leads to an implantable electrical supply unit formed separately from the implant. The invention is characterised in that the contact assembly has a spatial longitudinal extension which is oriented parallel to the winding axis, in that the contact assembly is fixedly joined to the carrier substrate along a joining region which has a joining region length oriented parallel to the winding axis (5), and in that the contact assembly in its orthogonal projection relative to the winding axis overlaps with the first region of the carrier substrate which is wound to form a tube.
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
An implantable electromechanical plug connector is described with a plug part and a socket part, of which the plug part has at least one joining portion which can be inserted completely into a unilaterally open insertion opening within the socket part and has at least one electrically insulating surface having at least one electrode body (6) with a freely accessible electrode surface, and of which the socket part has, inside the unilaterally open insertion opening, an electrically insulating wall portion which laterally delimits the insertion opening at least in part and whose surface makes available at least one counterelectrode body with a freely accessible counterelectrode surface, wherein the electrically insulating wall portion of the electrically insulating surface of the joining portion of the plug part, in the state of complete insertion of the plug part's joining portion in the insertion opening, is oriented in such a way that the counterelectrode surface touches the electrode surface, wherein the at least one electrode body (6) is raised in relation to the electrically insulating surface of the joining portion and/or the at least one counterelectrode body is raised in relation to the surface of the electrically insulating wall portion, and wherein at least one electrically insulating polymer layer is arranged at least in part between the electrically insulating surface of the joining portion and the surface of the electrically insulating wall portion, which polymer layer completely surrounds the mutually touching counterelectrode surface and electrode surface.
The invention relates to a method for producing a head part of an implantable medical device, comprising a head part housing that has a blind-hole-type recess along which, in a coaxial arrangement and in an an axially serial sequence, at least one electroconductive contact ring element and an electrically insulating, elastically deformable sealing ring, are non-positively joined to each other by an axial joining force, the at least one contact ring element and the at least one sealing ring being arranged along a rod-shaped assembly tool and non-positively joined to each other along the rod-shaped assembly tool by a joining force produced, and at least the at least one non-positively joined contact ring element arranged along the rod-shaped assembly tool and the at least one sealing ring are covered by a solidifiable sealing compound present in a flowable form. The method is characterised in that the joining force is produced between the at least one contact ring element and the sealing ring along the assembly tool by means of fixing means applied to the at least one contact ring element and sealing ring along the assembly tool, on both sides, at least one fixing means of which is fixed to the assembly tool in an axially movable and detachably axially fixed manner and is embodied in the form of a nut with an internal thread, which is brought into engagement with an external thread provided along the assembly tool, such that the fixing means embodied in the form of a nut is non-positively brought into engagement, on one side, generating a joining force, with the at least one contact ring element or sealing ring by relative rotation along the external thread of the assembly tool, and such that the rod-shaped assembly tool is detached and removed from the at least one contact ring element and the at least one sealing ring after the solidification of the sealing compound which mechanically supports the axial joining force in the form of a dimensionally stable matrix forming at least part of the head part housing.
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
B29C 45/14 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet en incorporant des parties ou des couches préformées, p. ex. moulage par injection autour d'inserts ou sur des objets à recouvrir
An apparatus for extravascular or extraneuronal fastening of an implant is described, said implant being locally longitudinally placeable along an intracorporeal vessel or a nerve fascicle by way of an interlocking and/or force-fit connection and being connected by means of at least one electrical incoming and outgoing cable to an implantable controller, with a separate embodiment to the implant, and/or to an implantable energy source. The invention is distinguished by virtue of the implant being connected to a fastening means, which are separated from the implant, by way of at least one connection means that transfers tensile forces, said fastening means being embodied in the form of cuffs or a helical structure and having assignable thereto a cylindrical lateral surface encompassing a cylindrical cavity, by means of which the fastening means is locally placeable, at least in regions, on an outer wall region of the vessel or the nerve fascicle with the formation of an interlocking and/or force-fit connection, and by virtue of the electrical incoming and outgoing cable leading to the controller and/or the energy source for receiving the tensile forces being applied directly or indirectly on the fastening means.
A biocompatible recording system includes a number of input channels for acquiring electronic information from the neural system of a living being. The recording system includes a preamplifier and further amplifier stages. An input of a second amplifier stage is coupled to an output of the preamplifier. A low-pass filter having a capacitance multiplier is connected to the second amplifier stage. The preamplifier of the recording system is designed using P-MOS technology.
The invention relates to a device for detecting at least one human vital parameter by means of a sensor, comprising a support which is suitably shaped and dimensioned so as to be removably placed at least partly in the human outer ear canal and to which at least one sensor is attached in order to detect a vital parameter. The invention is characterized in that the support is a flat substrate which is shaped in the form of a hollow cylinder, outwardly delimits a continuously open hollow channel radially to a cylindrical axis paired with the hollow cylinder, and has a hollow cylindrical outer wall region that at least partly contacts the surface of the human outer ear canal when the support is at least partly placed in the human outer ear canal.
The invention relates to an implantable electric connecting structure between an electric implant which has at least one electric conductor and an electric feed and drain line structure. The invention further relates to a method for producing an implantable electric connection between an electric implant. The invention is characterized in that the electric feed and drain line structure comprises at least one electric cable having a cable end, to which an electrically conductive flat piece is unsupportedly fitted, and that the at least one implant-side electric conductor is joined to the flat piece.
An implantable electrical contact arrangement is described which has at least one electrode body arrangement composed otherwise entirely of biocompatible, electrically insulating material, with at least one freely accessible electrode surface enclosed directly or indirectly by the biocompatible electrically insulating material. The invention is characterized in that the electrode body arrangement has a stack-shaped layer composite which provides at least one gold layer connected to an iridium layer via a diffusion barrier layer. The stack-shaped layer composite is otherwise completely encapsulated by an SiC layer, with the exception of at least one surface region of the iridium layer directed away from the layer composite. The SiC layer has an SiC layer surface which is directed away from the stack-shaped layer composite and which is adjoined directly or indirectly by the biocompatible, electrically insulating material.
The invention relates to an implantable electric multi-pole connection between an electric implant and an electric feed and discharge structure. The invention is characterised in that a flexible, film-like, electrically non-conductive, strip-shaped surface element is arranged between the implant and the feed and discharge structure. The surface element comprises at least one first surface, on which a number of electrodes n greater than of equal to two is arranged, which are respectively connected to the electric implant by means of electric connection conductors extending at least in parts inside the surface element. The electric feed and discharge structure comprises at least n lines which are electrically insulated from each other and which are electrically connected to one of the n electrodes. The strip-shaped surface element is wound around a winding axis, which adopts the shape of a helix, along a cover surface of a virtual cylinder provided with a cylinder axis which is straight or curved at least in sections.
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61B 5/04 - Mesure de signaux bioélectriques du corps ou de parties de celui-ci
An implantable electrical contact arrangement is described which has at least one electrode body arrangement composed otherwise entirely of biocompatible, electrically insulating material, with at least one freely accessible electrode surface enclosed directly or indirectly by the biocompatible electrically insulating material. The invention is characterized in that the electrode body arrangement has a stack-shaped layer composite which provides at least one gold layer connected to an iridium layer via a diffusion barrier layer. The stack-shaped layer composite is otherwise completely encapsulated by an SiC layer, with the exception of at least one surface region of the iridium layer directed away from the layer composite. The SiC layer has an SiC layer surface which is directed away from the stack-shaped layer composite and which is adjoined directly or indirectly by the biocompatible, electrically insulating material.
An implantable electromechanical plug connector is described with a plug part and a socket part, of which the plug part has at least one joining portion which can be inserted completely into a unilaterally open insertion opening within the socket part and has at least one electrically insulating surface having at least one electrode body (6) with a freely accessible electrode surface, and of which the socket part has, inside the unilaterally open insertion opening, an electrically insulating wall portion which laterally delimits the insertion opening at least in part and whose surface makes available at least one counterelectrode body with a freely accessible counterelectrode surface, wherein the electrically insulating wall portion of the electrically insulating surface of the joining portion of the plug part, in the state of complete insertion of the plug part's joining portion in the insertion opening, is oriented in such a way that the counterelectrode surface touches the electrode surface, wherein the at least one electrode body (6) is raised in relation to the electrically insulating surface of the joining portion and/or the at least one counterelectrode body is raised in relation to the surface of the electrically insulating wall portion, and wherein at least one electrically insulating polymer layer is arranged at least in part between the electrically insulating surface of the joining portion and the surface of the electrically insulating wall portion, which polymer layer completely surrounds the mutually touching counterelectrode surface and electrode surface.
The invention is an implantable electrode configuration having a carrier substrate of a biocompatible polymer in at least some areas and a freely accessible electrode surface applied to the carrier substrate or integrated into the carrier substrate on the carrier substrate surface in at least some areas is described and a method for producing the implantable electrode configuration. The electrode has a metallic base plate having a planar top side and bottom side, including at least one structural element protruding orthogonally from the top side. The planar surface of the metallic base plate is oriented parallel to the carrier substrate surface and the metallic base plate is enclosed by the biocompatible polymer, except for a first surface area of the at least one structural element which faces the carrier substrate surface and is the freely accessible electrode surface.
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61N 1/32 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
An implantable electrode arrangement provides spatially-selective detection of neuronal electrical signals, which propagate along at least one nerve fiber contained in a nerve fascicle, and for selective electrical stimulation of the at least one nerve fiber, comprising a biocompatible carrier substrate, which has at least one carrier substrate region that can be placed around the nerve fascicle in a cuff and has a straight cylinder-shaped carrier substrate surface which faces the nerve fascicle in the implanted state. The carrier substrate surface has an axial extension and an extension oriented circumferentially in a direction and a first electrode arrangement attached thereto. The electrode arrangement comprises in an axial sequence, at least three first electrode structures with at least two first electrode surfaces arranged in the circumferentially, and at least two spaced first electrode strips, displayed in the axial direction which extend circumferentially which are in a ring shape, which encloses the at least three electrode structures on both sides in the axial direction. The electrodes are connectable or are connected to a signal detector and generator.
An implantable assembly is described for acquisition of neuronal electrical signals at a selected location which propagate along at least one nerve fiber contained in a nerve fiber bundle, as well as for selective electrical stimulation of the at least one nerve fiber, having: an implantable electrode assembly (E) which is disposed on a biocompatible support substrate which can be positioned around the nerve fiber bundle in a cuff, which has a cylindrical support substrate surface (i) which in the implanted condition is orientated facing the nerve fiber bundle, on which a first electrode assembly for locationally selective acquisition of the neuronal electrical signals and selective electrical stimulation of the at least one nerve fiber, and on which a second electrode assembly is disposed to record an ECG signal, and an analysis and control unit (A/S) which can be electrically conductively connected or is connected to the implantable electrode assembly (E), in which the locationally selective acquired neuronal electrical signals as well as the ECG signal can be analyzed in a time-resolved manner such that a neuronal time signal correlated with a physiological parameter, such as blood pressure, can be derived.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
The invention relates to a biocompatible recording system having a number of input channels for acquiring electronic information from the neural system of a living being, comprising a preamplifier and further amplifier stages, wherein an input of a second amplifier stage is coupled to an output of the preamplifier and a low pass filter having a capacitance multiplier is connected to the amplifier of the second stage. The preamplifier of the recording system is designed using P-MOS technology.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Analytical, diagnostic and treatment apparatus for medical
purposes; electrodes and implants for use in
neurotechnology; electrodes and implants for vagus nerve
recording and stimulation; electrodes and implants for
electrical baroreflex recording and stimulation; medical
implants for vagus nerve and baroreflex recording and
stimulation containing electrodes in particular foil
electrodes, electronic control and/or evaluation units,
being supplied with energy by means of inductive procedures
or energy harvesting, communicating units by means of
digital radio signals (in particular ZigBee) or optical
signals, optionally provided with additional mechanical
sensors and actuators; accessories for the aforementioned
instruments, electrodes, and implants. Science and technology services in the field of neuroscience
and neurotechnology, research and development of medical
instruments, electrodes, and implants for vagus nerve and
baroreflex recording and stimulation as well as development
and analysis of intracorporal blood- pressure sensors in
particular ultrasound-based sensors. Medical services, medical and clinical treatment services in
particular vagus nerve and baroreflex recording and
stimulation using electrical power; therapeutic and medical
care.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Analytical, diagnostic and treatment apparatus for medical
purposes; medical electrodes and implants for use in
neurotechnology; medical implants for electrical and optical
nerve stimulation, containing electrodes and electronic
control and/or evaluation units, inductive procedures being
supplied with energy by means of inductive procedures or
energy harvesting, communicating with extracorporeal units
by means of radio signals or optical signals, optionally
provided with additional mechanical sensors and actuators;
accessories for the above-mentioned instruments, electrodes
and implants. Science and technology services in the field of neuroscience
and neurotechnology, research, development and production of
medical instruments, electrodes and implants for the
stimulation of nerves as well as development and analysis of
intracorporal blood-pressure sensors; software development
for application with medical instruments in the field of
neurosciences and neurotechnology. Medical services; advisory services relating to instruments
for medical diagnosis and treatment, in particular for nerve
stimulation using electrical power or light.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Analytical and medical diagnostic apparatus for medical purposes; treatment apparatus for medical purposes, namely, implantable neurostimulators for treating chronic diseases associated with autonomous vital functions; medical electrodes and active medical implants made of artificial materials for treating chronic diseases associated with autonomous vital functions for use in neurotechnology; Medical electrodes and active medical implants made of artificial materials for treating chronic diseases associated with autonomous vital functions for vagus nerve recording and stimulation; active medical implants made of artificial materials for treating chronic diseases associated with autonomous vital functions for vagus nerve and baroreflex recording and stimulation primarily composed of medical electrodes, namely, foil electrodes for medical use, and electronic control and evaluation units for controlling the vagus nerve stimulation and evaluating signals measured in connection with the vagus nerves function, all being supplied with energy by means of inductive procedures or energy harvesting, and communicating with extracorporeal units by means of digital radio signals or optical signals, and additional incorporated mechanical sensors and actuators; accessories for the aforementioned instruments, electrodes, and implants, namely, telemetry devices and systems for medical applications comprised of wireless receivers and wireless transmitters for receiving and transmitting information from and to the medical implants, and to personalize functions, monitoring devices and systems and sensors to measure, read, store, analyze, and control a medical implant, and to transmit vital signs and information relevant to medical conditions of the person, namely, movement, pressure, temperature, x-ray, electromagnetic radiation and light for reading, storing, analyzing and transmitting data from and to the telemetry device [ Science and technology services in the field of neuroscience and neurotechnology, namely, scientific research and development of medical instruments, electrodes, and implants for vagus nerve and baroreflex recording and stimulation, and development and medical research analysis of intracorporal blood-pressure sensors in the nature of ultrasound-based sensors ] [ Medical services, medical and clinical treatment services, namely, vagus nerve and baroreflex recording and stimulation using electrical power; therapeutic services in the nature of vagus nerve and baroflex stimulation for the treatment of high blood pressure ]
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Analytical and medical diagnostic apparatus, namely, medical devices and systems for diagnosing and analyzing patients' medical data retrieved from active artificial implanted devices and comprised of medical electrodes and electronic control and/or evaluation units therefor used in direct association with medical diagnosis apparatus, telemetry devices for medical applications, wireless receivers, wireless transmitters, and medical devices for monitoring vital signs, body movement, blood pressure, body temperature, x-ray imaging, and electromagnetic radiation and light measurements; treatment apparatus for medical purposes, namely, implantable neurostimulators being devices that provide electrical stimulation to nerves for treating chronic diseases associated with autonomous vital functions; medical electrodes and active medical implants consisting of artificial materials for treating chronic diseases associated with autonomous vital functions in neurotechnology; medical implants consisting of artificial materials for electrical and optical nerve stimulation primarily comprised of medical electrodes and electronic control and/or evaluation units therefor used in direct association with medical implants, for use in inductive procedures, supplied with energy by means of inductive procedures or energy harvesting, and capable of communicating with extracorporeal units by means of radio signals or optical signals, optionally provided with additional incorporated mechanical sensors and actuators; accessories for the above mentioned instruments, electrodes and implants, namely, telemetry devices for medical applications and systems comprised of medical implants of artificial materials and wireless receivers and wireless transmitters for use with medical implants of artificial materials for receiving and transmitting information from and to the implant and to personalize functions, and medical devices for monitoring vital signs and information relevant to medical conditions of the person, including but not limited to body movement, blood pressure, body temperature, x-ray images, and electromagnetic radiation and light measurements; systems comprised of telemetry devices for medical application and sensors for medical applications to measure, read, store, analyze, and control an implant, and transmit vital signs and information relevant to medical conditions of the person, including but not limited to body movement, blood pressure, body temperature, x-ray images, and electromagnetic radiation and light measurements Science and technology services in the field of neuroscience and neurotechnology, namely, scientific research, development and technological design of medical instruments, electrodes and implants for the stimulation of nerves as well as development and analysis of intracorporal blood-pressure sensors; software development for application with medical instruments in the field of neurosciences and neurotechnology Medical services; advisory services relating to instruments for medical diagnosis and treatment, in particular for nerve stimulation using electrical power or light
Described here is an implantable electrode arrangement for spatially-selective detection of neuronal electrical signals, which propagate along at least one nerve fibre contained in a nerve fascicle, and for selective electrical stimulation of the at least one nerve fibre, comprising a biocompatible carrier substrate (1), which has at least one carrier substrate region that can be placed around the nerve fascicle in a cuff-like manner and has a straight cylinder-shaped carrier substrate surface (1') oriented facing the nerve fascicle in the implanted state, said carrier substrate surface having an axial (a) extent and an extent oriented in the circumferential direction (U) and a first electrode arrangement (2) being attached thereto, said electrode arrangement comprising, in an axial sequence, at least three first electrode structures (3) with in each case at least two first electrode surfaces (4) arranged in the circumferential direction and at least two first electrode strips (5), which are spaced apart from one another in the axial direction, extend in the circumferential direction and in each case assume a ring shape, said first electrode strips enclosing the at least three electrode structures on both sides in the axial direction, and being connectable or connected to a signal detector and generator (6). The invention is distinguished by virtue of the fact that at least one second electrode arrangement (7) is arranged next to the first electrode arrangement (2) in the axial sequence on the straight cylinder-shaped carrier substrate surface (1') facing the nerve fascicle, said second electrode arrangement comprising -at least two second electrode strips (8) which are axially spaced apart from one another, extend in the circumferential direction (U) and in each case assume a ring shape, and -at least one second electrode structure (13), extending axially between the at least two second electrode strips (8), in each case comprising at least two second electrode surfaces (9) arranged equally distributed in the circumferential direction (U), and wherein the second electrode arrangement (7) is connected at least with the signal generator (6) or a further signal generator (6').
The invention relates to an implantable assembly for the locationally selective sensing of neuronal electrical signals and for selective electrical nerve stimulation, comprising the following components: an implantable electrode assembly (E) for the locationally selective sensing of the neuronal electrical signals, selective electrical stimulation, and the sensing of an EKG signal; an evaluating/control unit (A/S), in which the signals can be evaluated in a time-resolved manner in such a way that a neuronal time signal correlated to a physiological parameter, preferably blood pressure, can be derived; a comparator unit (K1), in which a time offset between the EKG signal and the neuronal time signal correlated with the physiological parameter can be determined; a function generator (F1), which generates, within a time frame determined by the evaluating/control unit (A/S) on the basis of the relative time offset, a stimulation signal, which is composed of a plurality of n individual pulses (EP) and which is adapted in phase and temporal amplitude progression to the derived neuronal time signal correlated with the physiological parameter; and a signal/current converter (SSW1), which conducts the stimulation signal for the selective electrical stimulation to the electrode assembly (2).
A61B 5/24 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
Described here is an implantable electrode arrangement for spatially-selective detection of neuronal electrical signals, which propagate along at least one nerve fibre contained in a nerve fascicle, and for selective electrical stimulation of the at least one nerve fibre, comprising a biocompatible carrier substrate (1), which has at least one carrier substrate region that can be placed around the nerve fascicle in a cuff-like manner and has a straight cylinder-shaped carrier substrate surface (1') oriented facing the nerve fascicle in the implanted state, said carrier substrate surface having an axial (a) extent and an extent oriented in the circumferential direction (U) and a first electrode arrangement (2) being attached thereto, said electrode arrangement comprising, in an axial sequence, at least three first electrode structures (3) with in each case at least two first electrode surfaces (4) arranged in the circumferential direction and at least two first electrode strips (5), which are spaced apart from one another in the axial direction, extend in the circumferential direction and in each case assume a ring shape, said first electrode strips enclosing the at least three electrode structures on both sides in the axial direction, and being connectable or connected to a signal detector and generator (6). The invention is distinguished by virtue of the fact that at least one second electrode arrangement (7) is arranged next to the first electrode arrangement (2) in the axial sequence on the straight cylinder-shaped carrier substrate surface (1') facing the nerve fascicle, said second electrode arrangement comprising -at least two second electrode strips (8) which are axially spaced apart from one another, extend in the circumferential direction (U) and in each case assume a ring shape, and -at least one second electrode structure (13), extending axially between the at least two second electrode strips (8), in each case comprising at least two second electrode surfaces (9) arranged equally distributed in the circumferential direction (U), and wherein the second electrode arrangement (7) is connected at least with the signal generator (6) or a further signal generator (6').
The invention relates to an implantable assembly for the locationally selective sensing of neuronal electrical signals and for selective electrical nerve stimulation, comprising the following components: an implantable electrode assembly (E) for the locationally selective sensing of the neuronal electrical signals, selective electrical stimulation, and the sensing of an EKG signal; an evaluating/control unit (A/S), in which the signals can be evaluated in a time-resolved manner in such a way that a neuronal time signal correlated to a physiological parameter, preferably blood pressure, can be derived; a comparator unit (K1), in which a time offset between the EKG signal and the neuronal time signal correlated with the physiological parameter can be determined; a function generator (F1), which generates, within a time frame determined by the evaluating/control unit (A/S) on the basis of the relative time offset, a stimulation signal, which is composed of a plurality of n individual pulses (EP) and which is adapted in phase and temporal amplitude progression to the derived neuronal time signal correlated with the physiological parameter; and a signal/current converter (SSW1), which conducts the stimulation signal for the selective electrical stimulation to the electrode assembly (2).
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
An implantable electrode arrangement is described, with a carrier substrate which is made at least in some areas from biocompatible polymer and on the carrier substrate surface of which there is, at least in some areas, a freely accessible electrode surface of an electrode that is applied to the carrier substrate or that is integrated in the carrier substrate. Furthermore, a method for producing the implantable electrode arrangement is explained. The invention is characterized in that the electrode has a metallic base plate with a plane top face and bottom face, with at least one structural element locally protruding orthogonally above the top face, in that the plane surface of the metallic base plate is oriented parallel to the carrier substrate surface, and in that the metallic base plate is completely enclosed by the biocompatible polymer directly and/or indirectly, except for a first surface area of the at least one structural element, which is oriented facing towards the carrier substrate surface and corresponds to the freely accessible electrode surface.
