BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Moroney, James V.
Machingura, Marylou C.
Bajsa-Hirschel, Joanna N.
Abrégé
Provided herein are green alga Cia8 polypeptides and the polynucleotides that encode them. Also provided herein are transformed cells and transgenic plants that include one or more of the polynucleotides and/or polypeptides provided herein.
C07K 14/40 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de champignons provenant de levures provenant de Candida
C07K 14/405 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'algues
C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
3.
Methods and compositions for thiol-acrylate based matertals for 3D cell culturing in a microfluidic device
Board of Supervisors of Louisiana State University (USA)
Inventeur(s)
Melvin, Adam
Pojman, John
Khan, Anowar
Abrégé
Provided are thiol-acrylate hydrogels and tunable cell culture materials including thiol-acrylate hydrogels, and methods of making thereof. Also provided are systems for forming three-dimensional cell culture scaffolds including the materials, and methods of culturing cells, including cancer cells, using thiol-acrylate hydrogels and tunable cell culture materials. The materials herein can be used in microfluidic droplet-generating devices.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
4.
Electrochemical reactor for upgrading methane and small alkanes to longer alkanes and alkenes
Board of Supervisors of Louisiana State University (USA)
Inventeur(s)
Arges, Christopher George
Flake, John C.
Fang, Yuxin
Abrégé
This application relates to new process that utilizes electrodes that incorporate acids that facilitate upgrading of methane and other low molecular weight alkanes to higher order hydrocarbon molecules, such as paraffins, olefins, and aromatics, at temperatures less than 250° C. A primary focus of the invention includes methane conversion to ethylene. The first step of the process includes acid containing electrodes that facilitate the activation of the alkane in the anode layer of the electrochemical reactor. Subsequent steps include the separation of protons from produced longer chain hydrocarbons followed by subsequent electrochemical reduction of the protons to yield hydrogen at the cathode or protons combined with oxygen at the cathode to yield water. The reaction steps in the anode upgrade methane to higher order hydrocarbon products.
Board of Supervisors of Louisiana State University (USA)
Inventeur(s)
Kuroda, Daniel
Fulfer, Kristen
Woodard, Kaylee Theresa
Abrégé
An energy storage apparatus is described and claimed herein comprising, generally, a battery housing enclosing a negative electrode, a positive electrode, and an electrolyte, wherein the electrolyte comprises a salt dissolved in either an amide-based solvent. In various embodiments, the amide-based solvent is a tertiary amide. Moreover, the energy storage apparatus may be a lithium ion battery that comprises an electrolyte with a lithium salt dissolved in a tertiary amide.
H01M 10/0569 - Matériaux liquides caracterisés par les solvants
H01M 10/0568 - Matériaux liquides caracterisés par les solutés
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Murray, Kermit King
Donnarumma, Fabrizio
Lawai, Oluwaremilekun
Abrégé
Laser ablation devices and methods including laser ablation are provided. The ablation devices can include a deep UV laser. Dual-laser ablation devices are also provided. Biomolecules can be ablated using a combination of deep UV laser and nanoelectrospray, resulting in protonated sample molecules.
H01J 49/04 - Dispositions pour introduire ou extraire les échantillons devant être analysés, p. ex. fermetures étanches au videDispositions pour le réglage externe des composants électronoptiques ou ionoptiques
G01N 33/483 - Analyse physique de matériau biologique
G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
B23K 26/12 - Travail par rayon laser, p. ex. soudage, découpage ou perçage sous atmosphère particulière, p. ex. dans une enceinte
H01J 49/16 - Sources d'ionsCanons à ions utilisant une ionisation de surface, p. ex. émission thermo-ionique ou photo-électrique
B23K 26/00 - Travail par rayon laser, p. ex. soudage, découpage ou perçage
B23K 26/16 - Enlèvement de résidus, p. ex. des particules ou des vapeurs produites pendant le traitement de la pièce à travailler
H01J 49/00 - Spectromètres pour particules ou tubes séparateurs de particules
G01N 1/04 - Dispositifs pour prélever des échantillons à l'état solide, p. ex. par coupe à l'outil
G01N 30/00 - Recherche ou analyse de matériaux par séparation en constituants utilisant l'adsorption, l'absorption ou des phénomènes similaires ou utilisant l'échange d'ions, p. ex. la chromatographie
Board of Supervisors of Louisiana State University (USA)
Inventeur(s)
Li, Guoqiang
Abrégé
A composition for sealing defects in structural materials such as roads or paved surfaces, the composition preferably comprising one or more shape memory polymer (SMP) components capable of responding to increased temperature by decreasing in volume.
C08L 101/12 - Compositions contenant des composés macromoléculaires non spécifiés caractérisées par des propriétés physiques, p. ex. anisotropie, viscosité ou conductivité électrique
C08F 299/02 - Composés macromoléculaires obtenus par des interréactions de polymères impliquant uniquement des réactions entre des liaisons non saturées carbone-carbone, en l'absence de monomères non macromoléculaires à partir de polycondensats non saturés
Board of Supervisors of Lousiana State University (USA)
Inventeur(s)
Hassan, Marwa
Aguirre Deras, Max Abelardo
Abrégé
Asphalt rejuvenating fibers and asphalt rejuvenation materials for self-healing asphalt applications are provided. The asphalt rejuvenating fibers can include a shell surrounding a hollow space. The shell can include alginate salts, an emulsifier, and a plasticizer. The asphalt rejuvenation materials can include the asphalt rejuvenating, an asphalt binder, and aggregate blends.
Board of Supervisors of Louisiana State University (USA)
Inventeur(s)
Kato, Naohiro
Abrégé
Provided for are methods of producing triacylglycerol-accumulated microalgae, methods for making bioplastics from triacylglycerol-accumulated microalgae, methods for making alga-mixed plastics, and products including these bioplastics. Methods of triacylglycerol accumulation using centrifugation are also provided. Products such as plastic beads and other consumer products can be made from the bioplastics described herein.
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Dahi Taleghani, Arash
Shojaei, Amir
Li, Guoqiang
Abrégé
The present disclosure provides for shape memory proppants, methods for making shape memory proppants, and methods of using shape memory proppants, and the like. The strong expandable proppants of the present disclosure may be used in maintaining fracture openings.
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Murray, Kermit King
Donnarumma, Fabrizio
Stephenson, Jamira
Abrégé
The present disclosure provides for sampling instruments and methods of collecting sample particles. The sampling instrument can include a high-pressure pulsed valve coupled to a gas flow system to displace a sample from a surface. Also included can be a voltage supply coupled to a voltage switch, a suction device, a sample collector, and a collection filter. To collect a sample, extractive particles can be deposited onto a sample present on a substrate. At least a portion of the sample becomes coupled to a portion of the extractive particles to form sample particles. High-pressure gas can be discharged at the sample, thereby aerosolizing a portion of the sample particles to disperse aerosolized sample particles. A portion of the aerosolized sample particles can be collected onto a collection filter to form a collected sample.
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Goeders, Nicholas E.
Schmoutz, Christopher Dalton
Abrégé
A method of treating a condition of in a human patient comprising pharmacologically activating a translocator protein of 18 kDa (TSPO), wherein the condition is one of a chronic methamphetamine addiction, a medical consequence of methamphetamine use; a behavioral consequence of methamphetamine use, an HIV associated cognitive motor disorder, an HIV-associated neurodegenerative disorder, and a neuroinflammatory response.
A61K 31/5513 - 1,4-Benzodiazépines, p. ex. diazépam
A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61K 31/603 - Acide salicyliqueSes dérivés ayant d'autres cycles aromatiques, p. ex. diflunisal
A61K 31/5517 - 1,4-Benzodiazépines, p. ex. diazépam condensées avec des cycles à cinq chaînons ayant l'azote comme hétéro-atome d'un cycle, p. ex. imidazobenzodiazépines, triazolam
A61K 31/501 - PyridazinesPyridazines hydrogénées non condensées et contenant d'autres hétérocycles
A61K 31/568 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes non substitués en position 17 bêta par un atome de carbone, p. ex. œstrane, œstradiol substitués en positions 10 et 13 par une chaîne ayant au moins un atome de carbone, p. ex. androstane, testostérone
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Cardelli, James Allen
Dragoi, Ana-Maria
El-Sayed, Khalid
Mohyeldin, Mohamed M.
Abrégé
A method of treating cancer or a precancer condition in a mammal comprising administering a therapeutically effective amount of a homovanillyl sinapate analog or pharmacologically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof, or a combination thereof.
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Yu, Weiyong
Zhang, Yu
Abrégé
An electroluminescent LED device comprising a hole transport layer, an electron transport layer, an active emissive layer between the hole transport layer and the electron transport layer, and carbon dots forming the active emissive layer.
H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
16.
Hydrophobically modified polypeptoids and uses thereof
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (USA)
Inventeur(s)
Zhang, Donghui
John, Vijay
Zhang, Yueheng
Xuan, Sunting
Abrégé
A variety of hydrophobically modified polypeptoids are provided. The hydrophobically modified polypeptoids can include a polyamide backbone having a random copolymer of two or more different types of repeat units, where one or more of the repeat units have nitrogen atom having a hydrophobic substituent attached thereto. Methods of making the hydrophobically modified polypeptoids are also provided, as well as uses of the hydrophobically modified polypeptoids, for example in liposomal drug delivery.
C08G 69/00 - Composés macromoléculaires obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principale de la macromolécule
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
A01N 37/18 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant le groupe —CO—N, p. ex. amides ou imides d'acide carboxyliqueLeurs thio-analogues
17.
Method for harvesting stem and progenitor cells and method of treatment of kidney disease and neurological disease
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Wang, Yuping
Abrégé
A method of generating one of podocyte progenitor cells and neural stem/progenitor cells comprising the steps of collecting a urine specimen from a patient; centrifuging the urine specimen; and removing the one of podocyte progenitor cells and neural stem/progenitor cells.
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Sunavala-Dossabhoy, Gulshan Neville
Mccarthy, Kevin
Abrégé
A load dissipating arthroplasty prosthesis comprising a shell, an articular device extending into the shell through a collar defined in the sell, a head and neck portion of the articular device extending from the collar, a shaft portion of the articular device extending into the shell, and a plurality of shock absorbing arcuate linkers spacing and allowing limited movement between the shell and the articular device.
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Dahi Taleghani, Arash
Li, Guoqiang
Abrégé
Methods for temporary fracture isolation are provided. An existing fracture is treated with a chemical diverter. The chemical diverter is exposed to conditions causing it to expand, plugging the fracture. A new fracture can be created through the application of pressure and fluid, without disrupting the plugged fracture. The chemical diverter can then be removed through biodegradation or the application of a solvent to reopen the first fracture.
C09K 8/516 - Compositions pour le plâtrage des parois de trous de forage, c.-à-d. compositions pour la consolidation temporaire des parois des trous de forage caractérisées par leur forme ou par la forme de leurs composants, p. ex. matériaux encapsulés
C09K 8/42 - Compositions de cimentation, p. ex. pour la cimentation des tubes dans les trous de forageCompositions de bouchage, p. ex. pour tuer des puits
20.
Isothiocyanatostilbenes as a novel method and product for treating cancer
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
BOARD OF SUPERVISORS FOR THE UNIVERSITY OF LOUISIA (USA)
Inventeur(s)
Gray, Alana Lea
Cardelli, James
Coleman, David Thomas
El-Sayed, Khalid
Mohyeldin, Mohamed M.
Abrégé
Products and methods for treating cancer in a human patient comprising administering to the patient therapeutically effective amount of a first pharmaceutically active agent, wherein the first pharmaceutically active agent is one of an isothiocyanatostilbene and a pharmacologically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof, or a combination thereof.
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Kevil, Christopher
Pardue, Sibile
Abrégé
Methods and therapeutics for treating nitric oxide (NO) mediated condition comprising administering a therapeutically effective amount of a pharmaceutical composition containing a therapeutic, wherein the therapeutic one of increases xanthine oxidase (XO) associated nitrite conversion to nitric oxide and increases nitrite conversion to nitric oxide via DADS. Method and devices for measuring an amount of nitrite in a sample comprising obtaining a sample, adding diallyl disulfide (DADS) to the sample, measuring a post DADS amount of nitric oxide (NO) in the sample, and using the post DADS amount of NO in the sample to determine the amount of nitrite in the sample. Methods and therapeutics for diagnosing and treating critical limb ischemia (CLI) versus non-critical limb ischemic peripheral artery disease (PAD) in a patient comprising determining a patient indicator value, where the patient indicator is value one of a total hydrogen sulfide metabolite plasma level, a total nitric oxide, nitrite, and nitrite (NOx) plasma level, a ratio of free hydrogen sulfide plasma level to total NOx plasma level, and a ratio of total hydrogen sulfide metabolite plasma level and total NOx plasma level, diagnosing the patient with as having CLI based on the patient indicator value, and administering to the patient a therapeutic for CLI.
G01N 33/84 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des composés inorganiques ou le pH
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
A61K 33/00 - Préparations médicinales contenant des ingrédients actifs inorganiques
22.
Use of an miRNA to reduce proliferation of a cancer cell
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Peruzzi, Francesca
Jeansonne, Duane
Abrégé
A method is provided for decreasing at least one of the proliferation and the migration of a cancer cell comprising contacting a cancer cell with an effective amount of a pharmaceutically acceptable composition comprising a microRNA (miRNA) having a nucleotide sequence having at least 80% sequence similarity to the nucleotide sequence of miR-3189-3p derived from the miR-3189 mitron of the Growth Differentiation Factor 15 (GDF15) gene. The methods and compositions are advantageous for inhibiting proliferation and migration of, but not limited to, glioblastoma cells, melanoma cells, and breast cancer cells.
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le ribosyle comme radical saccharide
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/7125 - Acides nucléiques ou oligonucléotides ayant des liaisons internucléosides modifiées, c.-à-d. autres que des liaisons 3'-5' phosphodiester
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Zhang, Donghui
Cao, Jinbao
Chan, Brandon
Siefker, David
Abrégé
Various embodiments disclosed relate to a method of forming a polypeptide. The method includes contacting a first amino acid-derived N-thiocarboxyanhydrosulfide monomer as a crystalline solid with a polymerization initiator (e.g., in an alkane suspension) to give a polypeptide product. The method further includes contacting the polypeptide product with a second amino acid-derived N-thiocarboxyanhydrosulfide monomer in an alkane suspension.
C08G 69/10 - Polyamides dérivés, soit des acides amino-carboxyliques, soit de polyamines et d'acides polycarboxyliques dérivés d'acides aminocarboxyliques d'acides alpha-aminocarboxyliques
24.
Tip enhanced laser assisted sample transfer for biomolecule mass spectrometry
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Murray, Kermit King
Ghorai, Suman
Seneviratne, Chinthaka Aravinda
Abrégé
Disclosed are various embodiments for transferring molecules from a surface for mass spectrometry and other sample analysis methods, and the like. A laser is focused onto a tip of an atomic force microscope to remove and capture a quantity of molecules from the surface, so they can be transferred to a mass spectrometer or another instrument for analysis.
H01J 49/00 - Spectromètres pour particules ou tubes séparateurs de particules
G01Q 30/02 - Dispositifs d'analyse d’un type autre que la microscopie à sonde à balayage SPM, p. ex. microscope électronique à balayage SEM [Scanning Electron Microscope], spectromètre ou microscope optique
B23K 26/16 - Enlèvement de résidus, p. ex. des particules ou des vapeurs produites pendant le traitement de la pièce à travailler
H01J 49/04 - Dispositions pour introduire ou extraire les échantillons devant être analysés, p. ex. fermetures étanches au videDispositions pour le réglage externe des composants électronoptiques ou ionoptiques
C12N 9/00 - Enzymes, p. ex. ligases (6.)ProenzymesCompositions les contenantProcédés pour préparer, activer, inhiber, séparer ou purifier des enzymes
C12N 15/00 - Techniques de mutation ou génie génétiqueADN ou ARN concernant le génie génétique, vecteurs, p. ex. plasmides, ou leur isolement, leur préparation ou leur purificationUtilisation d'hôtes pour ceux-ci
C12P 21/00 - Préparation de peptides ou de protéines
26.
Methods of differentiating preadipocytes and uses thereof
Board Of Supervisors Of Louisiana State University (USA)
Inventeur(s)
Eilertsen, Kenneth James
Rim, Jong
Abrégé
Described herein are methods of transdifferentiating preadipocytes, populations of transdifferentiated preadipocytes, and methods of using the transdifferentiated preadipocytes.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
THE UNIVERSITY OF NEW ORLEANS (USA)
Inventeur(s)
Shellito, Judd E.
Ramsay, Alistair John
Welsh, David A.
Ruan, Sanbao
Cai, Yang
Abrégé
Pneumocystis immune reaction by a recipient subject. The compositions and methods of the disclosure provide advantageous alternatives to available immunogenic determinants for the treatment or prevention of fungal pneumonia.
Board of Supervisors of Louisiana State University (USA)
Inventeur(s)
Wang, Yuping
Abrégé
A method of generating one of podocyte progenitor cells and neural stem/progenitor cells comprising the steps of collecting a urine specimen from a patient; centrifuging the urine specimen; and removing the one of podocyte progenitor cells and neural stem/progenitor cells.
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (USA)
Inventeur(s)
Ahmed, Osama
Abrégé
A cranial cap dressing for dressing a craniotomy wound comprising a breathable elastic outer layer sized to fit snuggly on a human head of a patient and an absorbent inner layer attached to the breathable elastic outer layer.
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament