The present invention addresses the problem of providing a method enabling determination of the state of differentiation of a cell at an early stage of differentiation. The present invention pertains to a "method for determining the state of differentiation of a cell, which method comprises detecting the expression of the FOXB1 gene in the cell that is tested, and on the basis of the result, performing the determination", and a "differentiation marker selected from mRNA or a protein derived from the FOXB1 gene".
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
A method for producing an azido-amine derivative includes obtaining an azido-amine derivative and extracting the azido-amine derivative obtained by using an aromatic solvent or an ether solvent.
C07C 209/42 - Préparation de composés contenant des groupes amino liés à un squelette carboné par réduction de liaisons azote-oxygène ou azote-azote par réduction de liaisons azote-azote
The present invention addresses the problem of providing a stabilizer of 8-amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)-dione (L-012) or a salt thereof with which it is possible to suppress a decline in measurement sensitivity caused by exposure to light without negative effects during measurement by causing the stabilizer to be jointly present with L-012 or a salt thereof. The present invention pertains to a stabilizer of L-012 or a salt thereof shown by general formula [1] and a method for stabilizing L-012 or a salt thereof by causing the stabilizer to be jointly present with L-012 or a salt thereof. (In the formula, p number of M1 each independently represent a hydrogen atom or alkali metal atom, q number of R1 each independently represent a hydroxyl group or sulfonic acid group, m represents 0 or 1, p represents an integer of 1-3, q represents an integer of 0-4, Y represents a nitrogen atom or CH group (methine group), and Z represents an aryl group having a specific structure or a pyrazolyl group having a specific structure.)
C09K 15/28 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'azote, de l'oxygène et du soufre
C07C 309/46 - Acides sulfoniques ayant des groupes sulfo liés à des atomes de carbone de cycles aromatiques à six chaînons d'un squelette carboné contenant des atomes d'azote, ne faisant pas partie de groupes nitro ou nitroso, liés au squelette carboné ayant les groupes sulfo liés à des atomes de carbone de cycles aromatiques à six chaînons non condensés
C07C 309/50 - Acides sulfoniques ayant des groupes sulfo liés à des atomes de carbone de cycles aromatiques à six chaînons d'un squelette carboné contenant des atomes d'azote, ne faisant pas partie de groupes nitro ou nitroso, liés au squelette carboné le squelette carboné étant substitué de plus par des atomes d'oxygène liés par des liaisons simples ayant au moins un des groupes sulfo lié à un atome de carbone d'un cycle aromatique à six chaînons faisant partie d'un système cyclique condensé
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
4.
ACID-RESISTANT BASE AND/OR RADICAL GENERATOR, AND CURABLE RESIN COMPOSITION CONTAINING SAID BASE AND/OR RADICAL GENERATOR
The present invention is a compound represented by general formula (A), a base and/or radical generator obtained by containing said compound, and the like. (In the formula: four R1 groups each independently represents a hydrogen atom or a fluorine atom; four R2 groups each independently represents a fluorine atom or a trifluoromethyl group; R3, R6, R7, and R10 each independently represents a hydrogen atom or a C1-12 alkyl group; R4 and R5 each independently represents a hydrogen atom or a C1-12 alkyl group, or R4 and R5 are bonded to each other to represent a C2-4 alkylene group; R8 and R9 each independently represents a hydrogen group, a C1-12 alkyl group, or a C6-14 aryl group which may have a substituent such as a C1-6 alkyl group, or R8 and R9 are bonded to each other to represent a C2-4 alkylene group, with the caveat that two to three of the eight R3-R8 groups are hydrogen atoms, three to six of the remaining groups are alkyl groups if two of the eight groups are hydrogen atoms, and four to five of the remaining groups are alkyl groups if three of the eight groups are hydrogen atoms).
C08G 59/68 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les catalyseurs utilisés
C08K 5/29 - Composés contenant des liaisons doubles carbone-azote
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
The present invention addresses the problem of providing a fixing method for a specific binding substance, capable of suppressing a phenomenon in which a positive line emerges even in a blank measurement in an immunotrap method, and providing a test device (carrier) capable of suppressing emergence of a positive line. The present invention pertains to: a fixing method for a specific binding substance, characterized by premixing a substance (specific binding substance) which specifically binds to a substance to be measured and a membrane solubilizing agent selected from the group consisting of n-octyl-β-D-glucoside, n-octyl-β-D-thioglucoside, n-dodecyl-β-D-maltoside, n-nonyl-β-D-thiomaltoside, and n-octanoyl-N-methyl-D-glucamine, and applying, onto a surface of a nonabsorptive carrier, a mixture liquid containing the specific binding substance and the membrane solubilizing agent, thereby fixing the specific binding substance to the surface; a nonabsorptive carrier obtained through the fixing method; and a measuring method for a substance to be measured in a sample, characterized by using the nonabsorptive carrier.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japon)
WAKO PURE CHEMICAL INDUSTRIES, LTD. (Japon)
Inventeur(s)
Tateno, Hiroaki
Warashina, Masaki
Fukuda, Masakazu
Hirayasu, Kazunari
Abrégé
Provided is a method for detecting a stem cell on the basis of an undifferentiated sugar chain marker having a specific sugar chain structure, wherein the stem cell is detected by detecting podocalyxin contained in a culture supernatant or a lysate of the cell by a "lectin-antibody sandwich method" that employs a combination of a lectin and an antibody and has high sensitivity. The method comprises the procedures of: bringing the culture supernatant or the lysate, a lectin capable of binding to a sugar chain represented by (formula 1) or (formula 2) and an antibody capable of binding to keratan sulfate into contact with one another to form a complex composed of the lectin, podocalyxin and the antibody; and detecting the complex.
The purpose of the present invention is to increase the dissociation efficiency between biotin in a biotinylated nucleic acid and Tamavidin 2 in a Tamavidin 2-immobilized insoluble support to thereby efficiently obtain the biotinylated nucleic acid. Provided are: a method for obtaining a biotinylated nucleic acid, said method comprising "(1) a step (step A-1) for contacting a sample containing a biotinylated nucleic acid wherein biotin is bound to a nucleic acid with an insoluble support on which Tamavidin is immobilized (a Tamavidin-immobilized insoluble support) and thus forming a complex of the biotinylated nucleic acid and the Tamavidin-immobilized insoluble support, and (2) a step (step A-2) for separating the biotinylated nucleic acid from the complex obtained in step (A-1) in a solution of pH 7.8-9.5 in the presence of free biotin"; a method for separating a biotinylated nucleic acid to which a nucleic acid-binding protein is bound; a method for separating a nucleic acid-binding protein; and a kit for separating a nucleic acid.
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
C07K 14/375 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de champignons provenant de Basidiomycetes
C07K 17/14 - Peptides immobilisés sur, ou dans, un support inorganique
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
Conventional quenchers do not have quenching capability to sufficiently suppress fluorescence emission of fluorescent compounds. The present invention addresses the problem of providing a quencher capable of sufficiently quenching the fluorescence of fluorescent compounds, such as xanthene dyes and the like. The present invention pertains to a quencher and the like comprising a compound represented by general formula (1). (1) {In the formula: each R5 independently represents a halogen atom, an alkyl group, an alkoxy group, an alkylthio group, a substituted or unsubstituted amino group, a hydroxyl group, an aryl group, an aryloxy group, or an arylalkyl group; R6 represents a group having a polymerizable unsaturated group, a hydroxyl group, or the like; Y1 represent an oxygen atom or the like; An- represents an anion; Ar1 represents a specific ring structure; * and ** represent a bonding position; Ar2 represents a benzene ring, a naphthalene ring, or an anthracene ring; and n1 represents a specific integer. Wherein, structure (1-10) in general formula (1) is asymmetrical. (1-10) (Therein, R5, Y1, Ar1, Ar2, n1, * and ** are as described above.)}
TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER
The present invention addresses the problem of providing a carrier and method for simply and efficiently obtaining or removing extracellular membrane vesicles or viruses present in a sample with high purity while keeping the vesicles or viruses intact, or detecting such vesicles or viruses with high sensitivity. The present invention relates to: "1. a carrier (Tim carrier) with which a protein (Tim protein) selected from T-cell immunoglobulin and mucin domain-containing molecule-4 (Tim-4) protein, Tim-3 protein, and Tim-1 protein, is bound; 2. a method for obtaining extracellular membrane vesicles or viruses in a sample; 3. a method for removing extracellular membrane vesicles or viruses in a sample; 4. a method for detecting extracellular membrane vesicles or viruses in a sample; 5. a kit for capturing extracellular membrane vesicles or viruses, wherein the kit includes the Tim carrier; and 6. a kit for capturing extracellular membrane vesicles or viruses, wherein the kit includes a reagent containing the Tim protein and a reagent containing the carrier".
The purpose of the present invention is to provide an electrolytic solution having a high oxidative decomposition potential, whereby dissolution and deposition of magnesium proceed repeatedly and stably, using a non-nucleophilic alkoxide-based magnesium salt. The present invention relates to: (1) an electrolytic solution for a magnesium cell, obtained by mixing a compound represented by general formula (I), a Lewis acid, and a solvent; (2) an electrochemical device including the electrolytic solution, a positive electrode, and a negative electrode; and (3) a compound represented by general formula (I’).
[Problem] To provide a device and method for the same for causing circular motion of a container in which a specimen, numerous small-diameter beads, and one large-diameter bead specimen are stored and fragmenting the specimen, wherein the specimen is fragmented efficiently and in a short time. [Solution] Numerous small-diameter beads (SB), one large-diameter bead (BB), and a solution (S) including a specimen are stored in a container (2). A drive part (40) causes circular motion of the bottom part of a stored container (2). A control part (70) controls the drive part (40) so that the bottom part of the container (2) undergoes circular motion which continuously varies between two or more mutually different rotation speeds.
The purpose of the present invention is to provide a cancer determination method and a cancer marker with which it is possible to accurately determine the cancerization of a cell and with which it is possible to determine the cancerization of various cells. The present invention relates to: "a cancer marker that consists of a portion of or the entirety of a base sequence represented by SEQ ID NO: 1 in a FOXB2 gene derived from a cell, and that includes at least a base sequence represented by SEQ ID NO: 3, and in which at least 30% of cytosine in -CG- sequences present in the base sequence is methylated"; "a cancer marker that consists of a portion of or the entirety of a base sequence represented by SEQ ID NO: 1 in a FOXB2 gene derived from a cell, and that includes at least a base sequence represented by SEQ ID NO: 2, and in which at least 30% of cytosine in -CG- sequences present in the base sequence is methylated"; and "a method involving measuring, by a bisulfite reaction, the methylation rate for a portion of or all of the cytosines in -CG- sequences present in a base sequence represented by SEQ ID NO: 1 in a FOXB2 gene derived from a cell, and determining the cancerization of the cell on the basis of said methylation rate".
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
13.
METHOD FOR DETERMINING STATE OF DIFFERENTIATION OF STEM CELLS, AND NOVEL DIFFERENTIATION MARKER USED THEREFOR
Provided is a method with which it is possible to determine, at an initial stage of differentiation, the state of differentiation of undifferentiated stem cells. The present invention relates to: "a method for determining the state of differentiation of a cell by detecting the expression of a FOXB2 gene in a stem cell, and performing the determination on the basis of the detection result"; and "a differentiation marker selected from an mRNA or a protein derived from a FOXB2 gene". The present invention is applicable to the quality management of stem cells and to methods for preparing and isolating differentiated cells. Further, because differentiated cells can be determined at an initial stage of culturing, the present invention is useful for early stage screening of cells and for the quality management of stem cells, and a reduction in culturing period and a reduction in expenditure regarding culture medium costs can be expected.
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
Provided are: a graft polymer that is free from fading and color migration due to bleed-out after coloring, which are defects of a dye, and does not deteriorate bright color development and transparency of a dye; a resin colored matter; a method for producing a resin colored matter; and a resin composition containing the resin colored matter. The present invention relates to: (1) a graft polymer that has a polyolefin (A) as the main chain, while having a polymer (B), which is obtained by polymerizing a dye (b) having a radically reactive functional group, in a side chain; (2) the graft polymer which is characterized in that the dye (b) having a radically reactive functional group is a cationic rhodamine derivative, cationic triarylmethane dye derivative or cationic cyanine dye derivative having an ethylenically unsaturated group; (3) a resin colored matter which is formed from the graft polymer; (4) a method for producing a resin colored matter, which is characterized by mixing a polyolefin (A), a dye (b) having a radically reactive functional group and a radical reaction initiator (C), and causing a radical reaction of the mixture; and the like.
C08F 8/30 - Introduction d'atomes d'azote ou de groupes contenant de l'azote
C08F 255/02 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères d'hydrocarbures tels que définis dans le groupe sur des polymères d'oléfines contenant deux ou trois atomes de carbone
C08L 23/00 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
C09B 69/10 - Colorants polymèresProduits de réactions de colorants avec des monomères ou avec des composés macromoléculaires
A practical range of heat resistance could not be achieved in conventional colored resin compositions that used a triarylmethane derivative. The present invention thus addresses the problem of providing a colored composition having higher heat resistance than conventional colored compositions. The present invention relates to a compound represented by general formula (1), and a polymer or the like having a monomer unit derived from said compound. (In the formula, R1 to R4 are each independently an alkyl group or the like, R5 to R7 are each independently a hydrogen atom or a methyl group, an n number of R8 are each independently a halogen atom, an alkyl group, an aryl group, a hydroxyl group, a nitro group, a sulfo group, an alkoxy group or the like, and n is an integer from 0 to 4. A1 is an alkylene group or the like, and A2 is -NH- or -O-. An- is an aryl group having a substituent with an electron-withdrawing property, a sulfonyl group having a substituent with an electron-withdrawing property, or an anion including an alkyl halide group.)
The present invention addresses the problem of providing a method for specifically assaying CK-MB while avoiding the influence of CK-BB. Provided is a method for assaying CK-MB in a sample, said method comprising: a step for reacting the sample with a first antibody against CK-MB, a second antibody against CK-MB that recognizes a different epitope from the first antibody, and an anti-CK-B antibody that recognizes the 1st to 100th region from the N-end in the amino acid sequence of the B subunit of creatine kinase [step (1)]; a step for measuring an optical change that is caused by the aforesaid reaction [step (2)]; and a step for determining the quantity of CK-MB in the sample on the basis of the result obtained in step (2) [step (3)]. Also provided are: a kit to be used in the method; and a method for avoiding the influence of CK-BB in assaying CK-MB, said method being characterized by comprising treating a sample with the anti-CK-B antibody as described above.
G01N 33/573 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour enzymes ou isoenzymes
G01N 21/82 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un précipité ou une turbidité
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
This invention addresses the problem of providing an electrode with which excellent charge/discharge capacity can be obtained even when an active material containing silicon is used. The present invention pertains to: a binder for a lithium cell comprising a polymer that has, as constituent elements, an acrylic acid-derived monomer unit and one or two monomer units derived from compounds represented by general formulae (I), (II), or (III), the binder being crosslinked by a crosslinking agent selected from compounds indicated in general formulae [1]-[13] and the monomer indicated in general formula [14]; a composition for producing an electrode of a lithium cell, the composition containing 1) a silicon-containing active material, 2) an electroconductive aid, and 3) the binder for a cell; and an electrode for a lithium cell having 1) a silicon-containing active material, 2) a conductive aid, 3) the binder for a cell, and 4) a collector.
A method for purifying polynucleic acids is disclosed, comprising adsorbing the polynucleic acids to a filter, washing the filter with a water-immiscible solution, and eluting the polynucleic acids from the filter. The method can be used to prepare purified RNA and/or DNA.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
Conventional coloring resin compositions obtained using rhodamine derivatives could not achieve a practical degree of heat resistance. As a result, the present invention addresses the problem of providing a coloring composition that exhibits higher heat resistance than conventional coloring compositions. The present invention relates to a compound represented by general formula (1) and to a polymer or the like having a monomer unit derived from the compound. (In the formula, R1 to R4 are each independently a hydrogen atom, an alkyl group, or the like, R7 is a hydrogen atom or a methyl group, R8 and R9 are each independently a hydrogen atom or an alkyl group, Y is a nitrogen atom or a group represented by formula (1-1), A1 is an alkylene group or the like having, in the chain, at least one group selected from among -O-, -OCO-, -COO-, -NHCO-, -CONH-, -NHCONH- and an arylene group, and A2 is -NH- or -O-. An- is an anion that contains an aryl group or the like having an electron-withdrawing substituent group and n is an integer between 0 and 3. R8 and R9 may form a 5 to 6-membered ring structure together with the -N-(CH2)n-Y- group that links R8 to R9.)
The purpose of the present invention is to provide a cyanine coloring composition having higher heat resistance than conventional coloring compositions, and the present invention pertains to a compound represented by general formula (1), a polymer having monomer units from this compound, and a coloring composition, coloring composition for a color filter, and colored resin containing this compound or this polymer.
The present invention addresses the problem of providing: a compound that is capable of forming a composition having good shelf life such that even if the compound is stored long term in a state of being mixed with a base-reactive compound such as an epoxy compound, reaction with the base-reactive compound does not occur, and that is capable of generating a strong base (a guanidine, biguanide, phosphazene, or phosphonium) when irradiated with light (active energy rays) or heated; a base generator comprising the compound; and a base-reactive composition comprising the base generator and the base-reactive compound. The present invention relates to a compound represented by general formula (A), a base generator comprising the compound, a base-reactive composition characterized in comprising the base generator and a base-reactive compound, and the like. (In the formula, R1 is an alkyl group; an arylalkynyl group optionally substituted by a halogen atom, alkyl group, alkoxy group, or alkylthio group; an alkenyl group; a 2-furylethynyl group; a 2-thiophenylethynyl group; or a 2,6-dithianyl group. R2 through R4 are each independently an alkyl group; an arylalkynyl group optionally substituted by a halogen atom, alkyl group, alkoxy group, or alkylthio group; an aryl group optionally substituted by a halogen atom, alkyl group, alkoxy group, or alkylthio group; a furanyl group; a thienyl group; or an N-alkyl-substituted pyrrolyl group. Z+ is an ammonium cation comprising a guanidinium group, biguanidium group, or phosphazenium group, or a phosphonium cation.)
C07C 279/26 - X et Y étant des atomes d'azote, c.-à-d. biguanides
C07D 233/48 - Atomes d'azote ne faisant pas partie d'un radical nitro avec des radicaux hydrocarbonés acycliques ou des radicaux hydrocarbonés acycliques substitués, liés auxdits atomes d'azote
The present invention addresses the problem of providing a colouring composition which exhibits higher heat resistance than conventional colouring compositions. The present invention relates to a compound or the like represented by general formula (1) (in the formula: R1-R4 and R14 each independently represent hydrogen, a C1-30 alkyl group, a phenyl group which has a substituent or which is unsubstituted, a naphthyl group, or a benzyl group; R5-R7 each independently represent hydrogen or a methyl group; and R8-R13 each independently represent a C1-21 alkyl group, an aryl group, a hydroxyl group, a nitro group, a sulfo group, or a C1-3 alkoxy group. Furthermore, A1 represents: a C1-21 alkylene group which has, in the chain thereof, at least one group from among -N(R15)-, -O-, -OCO-, -COO-, and an arylene group, and which has a hydroxyl group as a substituent; a C1-21 alkylene group which has, in the chain thereof, at least one group from among -N(R15)-, -O-, -OCO-, -COO-, and an arylene group; a C1-21 alkylene group which has a hydroxyl group as a substituent; or a C1-21 alkylene group. Moreover, A2 represents -NH- or O-, R15 represents hydrogen, a C1-30 alkyl group, a phenyl group which has a substituent or which is unsubstituted, a naphthyl group, or a benzyl group, and An- represents an anion which includes: an aryl group having an electron-withdrawing substituent; a sulfonyl group having an electron-withdrawing substituent; or a halogenated alkyl group.).
The present invention addresses the problem of providing: an acid- and radical-generating agent which has high sensitivity to an active energy ray having a wavelength of about 300 to 450 nm, can exhibit both high acid-generating ability and high radical-generating ability, and has heat resistance; and a method for producing an acid and a radical. The present invention relates to: a compound represented by general formula (A); an acid- and radical-generating agent comprising the compound; and a method for producing an acid and a radical. (In the formula, n R1's independently represent an alkyl group which may have a specific functional group in the chain and may be substituted by a halogen atom, an alkoxy group which may be substituted by a halogen atom, an aryl or aryloxy group which may be substituted by a halogen atom, an alkyl group or a haloalkyl group, or an arylalkyl or arylalkyloxy group which may be substituted by a halogen atom, an alkyl group or a haloalkyl group; n R2's and n R3's independently represent a hydrogen atom, an alkyl group or an alkoxycarbonyl group; R4 to R7 independently represent a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, an alkenyl group, an aryl group, an alkoxycarbonyl group, a dialkylamino group or a nitro group; Y represents an oxygen atom, a sulfur atom or a carbonyl group; n Z's independently represent a sulfonyl group or an alkoxyphosphoryl group; and n represents 1 or 2.)
C07C 317/24 - SulfonesSulfoxydes ayant des groupes sulfone ou sulfoxyde et des atomes d'oxygène, liés par des liaisons doubles, liés au même squelette carboné
C07C 317/44 - SulfonesSulfoxydes ayant des groupes sulfone ou sulfoxyde et des groupes carboxyle liés au même squelette carboné
C07D 335/16 - Atomes d'oxygène, p. ex. thioxanthones
The present invention relates to a cleaning agent for semiconductor substrates, which is used in a step after a chemical mechanical polishing step for a semiconductor substrate that comprises a cobalt-containing film and a copper wiring film or a copper alloy wiring film. This cleaning agent for semiconductor substrates is characterized by containing (A) an organic acid represented by a general formula set forth in the description, (B) an amine selected from among (B-1) diamines, (B-2) amidines, (B-3) azoles and (B-4) pyrazines or pyrimidines respectively represented by general formulae set forth in the description, (C) a hydroxyl amine derivative and (D) a deoxidizing agent represented by a general formula set forth in the description, and is also characterized by being an aqueous solution having a pH of 10 or more. The present invention also relates to a method for processing a semiconductor substrate surface comprising a cobalt-containing film and a copper wiring film or a copper alloy wiring film. This method for processing a semiconductor substrate surface is characterized by using the above-described cleaning agent.
The present invention addresses the problem of providing a method for producing a sulfonium salt compound, with which a sulfonium salt compound having a variety of counter anions, particularly a sulfonium salt compound having weak acid-derived counter anions, can be efficiently produced, as well as providing a hydrogen carbonate sulfonium salt that is useful as a starting material in the method for producing a sulfonium salt compound. The present invention pertains to the following: a method for producing a sulfonium salt compound represented by general formula (2), which is characterized in that a hydrogen carbonate sulfonium salt represented by general formula (1) and an organic acid are reacted; and a hydrogen carbonate sulfonium salt represented by general formula (1'). (The symbols in the formulas are as defined in the specification.)
The objective of the present invention is to provide: an etching agent for a titanium-based metal on a semiconductor substrate, which is suppressed in decomposition of hydrogen peroxide, has a long service life, and has less need for control of the hydrogen peroxide concentration in the etching agent even in cases where the etching agent is used for a semiconductor substrate that has a titanium-based metal and copper metal or a copper alloy; an etching method; and an etching agent preparation liquid which is mixed with hydrogen peroxide for use. The present invention relates to: an etching agent for a titanium-based metal on a semiconductor substrate which has the titanium-based metal and copper metal or a copper alloy arranged on top of the titanium-based metal, said etching agent being an aqueous solution that contains at least (A) hydrogen peroxide, (B) a phosphonic acid-based chelating agent having a nitrogen atom in the structure, (C) an alkali metal hydroxide and (D) an organic acid having at least one hydroxyl group and at least three carboxyl groups; an etching method which is characterized by using this etching agent; and an etching agent preparation liquid which is mixed with hydrogen peroxide for use.
The present invention addresses the problem of providing: a base generator which has high solubility in widely used organic solvents, can be dissolved directly in a base-reactive compound such as an epoxy compound, has both high heat resistance and low nucleophilicity, and enables the generation of a strong base; a base-reactive composition comprising the base generator and a base-reactive compound; a method for generating a base; and others. The present invention relates to: a compound represented by general formula (A); a base generator comprising the compound; a base-reactive composition characterized by comprising the base generator and a base-reactive compound; a method for generating a base; and others. (In the formula, R1 to R5 independently represent a hydrogen atom, an alkyl group, an aryl group which may have a substituent, or an arylalkyl group which may have a substituent; R6 represents a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group, an alkynyl group, an aryl group which may have a substituent, or an arylalkyl group which may have a substituent; R7 represents a hydrogen atom, an alkyl group which may have an amino group, an aryl group which may have a substituent, or an arylalkyl group which may have a substituent; and Z- represents an anion derived from a carboxylic acid having a specific structure.)
C07C 59/84 - Composés non saturés contenant des groupes cétone contenant des cycles aromatiques à six chaînons
C07C 65/28 - Composés comportant des groupes carboxyle liés à des atomes de carbone de cycles aromatiques à six chaînons et contenant l'un des groupes OH, O-métal, —CHO, cétone, éther, des groupes , des groupes ou des groupes contenant des groupes éther, des groupes , des groupes ou des groupes avec des insaturations autres que celles des cycles aromatiques
C07C 279/26 - X et Y étant des atomes d'azote, c.-à-d. biguanides
The purpose of the present invention is to obtain an organic thin film transistor having a structure in which the reliability of the achievement of a characteristic-improving effect is improved. The present invention is an organic thin film transistor (1) that is provided with an organic semiconductor layer (40), a source electrode (50), a drain electrode (60), a gate electrode (20), and a gate insulating film (30) and wherein: a first high-concentration section (43) is provided in an area within the organic semiconductor layer (40) that extends toward the drain electrode (60) side from an end position (A) of the source electrode (50) on the drain electrode side to a position defined by a distance (x1), said high-concentration section (43) having a higher concentration of impurities than the concentration of impurities in the area on the drain electrode (60) side that is adjacent to the aforementioned area; and, when the distance between the source electrode (50) and the drain electrode (60) is L, x1 < L.
H01L 21/28 - Fabrication des électrodes sur les corps semi-conducteurs par emploi de procédés ou d'appareils non couverts par les groupes
H01L 51/05 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés au redressement, à l'amplification, à la génération d'oscillations ou à la commutation et ayant au moins une barrière de potentiel ou une barrière de surface; Condensateurs ou résistances à l'état solide, ayant au moins une barrière de potentiel ou une barrière de surface
H01L 51/40 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
29.
THIOXANTHENE COMPOUND, BASE AMPLIFIER, AND BASE-REACTIVE RESIN COMPOSITION CONTAINING BASE AMPLIFIER
Provided are: a base amplifier that can be used in the cross-linking reaction of an epoxy compound or the like, that is capable of generating a new base as a result of the presence of a base, that is highly soluble with respect to organic solvents, and that can efficiently promote a base proliferation reaction when added to a base-reactive compound as a result of having higher heat resistance than conventional base amplifiers; and a base-reactive resin composition containing the base amplifier. The present invention relates to a thioxanthene compound that is represented by formula (A), a base amplifier, and a base-reactive resin composition that contains the base amplifier.
The present invention relates to a cleaning agent for a substrate having metal wiring, the agent characterized by being used in a cleaning step following chemical mechanical polishing (CMP) in a semiconductor element production process, and characterized by comprising an aqueous solution which has a pH of 10 or higher and contains (A) a carboxylic acid which has a nitrogen-containing heterocyclic ring and (B) an alkylhydroxylamine. The present invention also relates to a method for cleaning a semiconductor substrate, the method characterized by using the cleaning agent.
The present invention provides: a breast-cancer marker selected from the group consisting of fucosylated hornerin, fucosylated Zn-α-2-glycoprotein, fucosylated Ig γ-1 chain C region, and fucosylated desmoplakin; a breast-cancer determination method in which the breast-cancer marker is detected in a specimen, and determination is conducted on the basis of a detection result; and a kit to be used in said breast-cancer determination method.
The present invention addresses the problem of providing a colored composition having higher heat resistance compared with conventional colored compositions. The present invention relates to: "a polymer having a monomer unit derived from a monomer which has both (i) a cationic rhodamine derivative having, as an counter anion, an anion containing an aryl group having an electron-withdrawing substituent and an anion group and (ii) an ethylenically unsaturated bond"; "a monomer which has both (i) a cationic rhodamine derivative having, as an counter anion, an anion containing an aryl group having an electron-withdrawing substituent and an anion group and (ii) an ethylenically unsaturated bond"; "a colored composition containing the polymer or the monomer"; and "a colored composition for a color filter, which contains the polymer or the monomer".
C08F 220/36 - Esters contenant de l'azote contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle
C07C 309/29 - Acides sulfoniques ayant des groupes sulfo liés à des atomes de carbone de cycles aromatiques à six chaînons d'un squelette carboné de cycles aromatiques à six chaînons non condensés
The purpose of the present invention is to provide an electrochemical device which is provided with an electrolyte solution, which exhibits a high current density and excellent safety, and with which dissolution and deposition of magnesium are stably repeated. Furthermore, the present invention relates to an electrolyte solution for the electrochemical device, said electrolyte solution including (1) a supporting electrolyte comprising a magnesium salt, and (2) at least one compound represented by general formula (I) (in general formula (I): n represents an integer in the range 0-6; the n R1s and the n R2s each independently represent hydrogen, a C1-6 alkyl group, or a C1-6 halogenoalkyl group; and A1 and A2 each independently represent -C(=O)-R3, -O-R5, -N(R4)-R3, -S-R3, -C(=O)-OR3, -O-C(=O)-R3, -C(=O)-N(R4)-R3, -N(R4)-C(=O)-R3, -SO2-R3, -N(R4)-SO2-R3, -O-B(OR5), -O-P(=O)(OR5)2, -CN, a monocyclic heterocyclic group, a cyclic acetal-derived group, a cyclic carbonate ester-derived group, or a cyclic carboxylic acid ester-derived group).
The present invention addresses the issue of providing a method for detecting hydroxymethylated cytosine in DNA and a detection kit therefor. The present invention pertains to: "a method for detecting hydroxymethylated cytosine in DNA, characterized by comprising: (1) a step in which (i) a polyvalent metal oxide or a polyvalent metal salt, having metal atoms selected from group 6, 8, 9, or 10 in the periodic table and (ii) a peroxide selected from persulfuric acid, percarboxylic acid, or salts thereof are caused to come in contact with a single-stranded DNA; (2) a step in which a specified area of the single-stranded DNA having step (1) performed thereon is amplified; (3) a step in which the presence of the target amplification product obtained in step (2) is detected; and a step (4) in which the presence of hydroxymethylated cytosine in the specified area in the DNA is determined"; and "a reagent kit for detection of hydroxymethylated cytosine in DNA, comprising a reagent including said peroxide and the polyvalent metal oxide or the polyvalent metal salt."
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
The present invention addresses the problem of providing an electrode capable of maintaining excellent capacity retention without the electrode structure being destroyed, even when an active material containing silicon is used. The present invention pertains to: a binder for a lithium cell, the binder comprising polyacrylic acid crosslinked by a crosslinking agent selected from compounds set forth in general formulae (1)-(13), and a polymer set forth in general formula (14) (excluding those containing a functional group-containing vinylidene fluoride polymer); to a composition for producing an electrode of a lithium cell, the composition including 1) an active material containing silicon, 2) an electroconductive additive, and 3) a crosslinked polyacrylic acid (excluding those containing a functional group-containing vinylidene fluoride polymer); and to an electrode for a lithium cell, the electrode having 1) an active material containing silicon, 2) an electroconductive additive, 3) a crosslinked polyacrylic acid, and 4) a collector (excluding those containing a functional group-containing vinylidene fluoride polymer).
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
H01M 4/134 - Électrodes à base de métaux, de Si ou d'alliages
H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
C08F 220/06 - Acide acryliqueAcide méthacryliqueLeurs sels métalliques ou leurs sels d'ammonium
C08G 59/40 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les agents de durcissement utilisés
C08K 5/29 - Composés contenant des liaisons doubles carbone-azote
C08L 33/02 - Homopolymères ou copolymères des acidesLeurs sels métalliques ou d'ammonium
C08L 63/00 - Compositions contenant des résines époxyCompositions contenant des dérivés des résines époxy
C08L 79/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant uniquement de l'azote, avec ou sans oxygène ou carbone, non prévues dans les groupes
36.
NOVEL COMPOUND, AND METHOD FOR MEASURING IRON CONCENTRATION BY USING NOVEL COMPOUND AS CHELATE COLOR FORMER
The present invention addresses the problem of providing a chelate color former which can measure the concentration of iron with high sensitivity and with low blank values when measuring the concentration of iron, and an iron concentration measurement method and kit that use this chelate color former. The present invention relates to the following: a compound represented by formula [1] or a salt thereof (in the formula, R1 and R2 each independently represent -SO3H or -CO2H); an iron concentration measurement method in which the compound is used as a chelate color former, the compound is brought into contact with iron in a sample, and the concentration of iron in the sample is measured on the basis of the degree of color development; and a kit used in the measurement method.
G01N 31/00 - Recherche ou analyse des matériaux non biologiques par l'emploi des procédés chimiques spécifiés dans les sous-groupesAppareils spécialement adaptés à de tels procédés
G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur
G01N 33/84 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des composés inorganiques ou le pH
37.
NONAQUEOUS SECONDARY CELL, AND FIRE-RETARDANT AGENT AND ADDITIVE FOR NONAQUEOUS SECONDARY CELL
A nonaqueous secondary cell provided with a positive electrode, a negative electrode, and a nonaqueous electrolytic solution, the nonaqueous secondary cell containing at least a cyclic nitrogen-containing compound expressed by formula (1) below in the nonaqueous electrolytic solution. (In the formula, R1 is selected from: a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkoxy group, a lower alkoxycarbonyl group, a lower alkyl carbonyl group, and an aryl group; R2 is selected from: a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkoxy group, a lower alkoxycarbonyl group, a lower alkyl carbonyl group, and an aryl group; or, R1 and R2 are bonded together, and are selected from a cyclic structure containing any of a methylene group, a vinylene group, and a bivalent linking group including a complex atom.)
The present invention relates to: a breast cancer marker which is selected from the group consisting of carboxypeptidase N subunit 2, extracellular matrix protein 1, serum amyloid P component, nebulin, complement component C8 α chain, apolipoprotein L1, flavin reductase, catalase, carbonic anhydrase 2, apolipoprotein C-I, nuclear pore glycoprotein 210, superoxide dismutase [Cu-Zn], bisphosphoglycerate mutase, carbonic anhydrase 1 and peroxiredoxin 2; a method for determining breast cancer, which comprises detecting the breast cancer marker in a sample and determining breast cancer on the basis of the results of the detection; and a kit for use in the method.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
The purpose of the present invention is to provide a practical method for producing a cyclic carbonate, which is widely used for various applications such as electrolytic solutions for lithium-ion secondary batteries and plastic materials, by a reaction between an epoxide (oxirane) and carbon dioxide, the method giving consideration to the reduction of environmental loads and making it possible to produce said cyclic carbonate with high yield under mild conditions, such as at room temperature and atmospheric pressure. The present invention relates to a method for producing a cyclic carbonate, the method being characterized by reacting an epoxide and carbon dioxide in the presence of an iodine-anion-containing phosphonium salt and a compound including a hydrogen atom that can form a hydrogen bond with an oxygen atom in the epoxide.
The purpose of the present invention is to provide a practical method for producing a cyclic carbonate, which is widely used for various applications such as electrolytic solutions for lithium-ion secondary batteries and plastic materials, by a reaction between an epoxide (oxirane) and carbon dioxide, the method giving consideration to the reduction of environmental loads and making it possible to produce said cyclic carbonate with high yield under mild conditions, such as at room temperature and atmospheric pressure. The present invention relates to a method for producing a cyclic carbonate, the method being characterized by reacting an epoxide and carbon dioxide in the presence of an iodine-anion-containing phosphonium salt including a hydrogen atom that can form a hydrogen bond with an oxygen atom in the epoxide.
An alkali etching fluid for solar cell production, including (A) a compound indicated in general formula [1], disulfonic acid, or a salt of either, (B) an alkali compound, and (C) water; and a production method for a silicon-based substrate for solar cell production, characterized by using the etching fluid and etching a wafer having silicon as the main component thereof, and by forming an uneven structure on the surface of the wafer. (In the formula, the p number of R1 each independently indicate a hydrogen atom, a hydroxyl group, or a C1-10 alkyl group, the q number of M each independently indicate a hydrogen atom, an alkali metal atom, an ammonium (NH4) group, or a tetraalkyl ammonium (R24N) group (in the formula, R2 indicates a C1-4 alkyl group), n indicates 0 or 1, and p and q each independently indicate 1 or 2.)
H01L 21/308 - Traitement chimique ou électrique, p. ex. gravure électrolytique en utilisant des masques
H01L 31/04 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV]
42.
CLEANING AGENT FOR SEMICONDUCTOR SUBSTRATES AND METHOD FOR PROCESSING SEMICONDUCTOR SUBSTRATE SURFACE
The purpose of the present invention is to provide: a cleaning agent for semiconductor substrates, which excellently removes fine polishing particles of silica, alumina or the like remaining on a semiconductor substrate surface, in particular on a silicon oxide film surface such as a TEOS film after a chemical mechanical polishing process, while having excellent non-corrosive properties for tungsten wiring lines or tungsten alloy wiring lines; and a method for processing a semiconductor substrate surface. The present invention relates to: a cleaning agent for semiconductor substrates, which is used in a post-process of a chemical mechanical polishing process for a semiconductor substrate that comprises a tungsten wiring line or a tungsten alloy wiring line and a silicon oxide film, and which is characterized by containing (A) a phosphonic acid-based chelating agent, (B) a primary or secondary monoamine having at least one alkyl group or hydroxyalkyl group in each molecule and (C) water, and is also characterized by having a pH of more than 6 but less than 7; and a method for processing a semiconductor substrate surface.
Methods for analyzing reaction products from an assay chamber (11) in a microfluidic device comprise the steps of (I) moving a sample from the chamber (11) into a load channel (12), towards a separation channel (4), and (III) analyzing the sample present at an intersection (16) of the load channel (12) and the separation channel (4), by electrophoretic separation in the separation channel (4). During this separation, the step of (II) moving a next sample inside the load channel, towards a preload channel (13), is carried out.
The purpose of the present invention is to provide a method that can accurately detect DNA having a microsatellite region without causing the problem of non-specific reaction products. The present invention relates to a "method for detecting DNA having a microsatellite region by (1) bringing a probe, which does not have a nucleotide sequence complementary to the microsatellite region and which will hybridize with the nucleotide sequences on both sides of the microsatellite region, into contact with DNA having the microsatellite region, and forming a hybrid of the probe and the DNA, said hybrid having a loop structure containing the microsatellite region, (2) separating the obtained hybrid, and (3) detecting the hybrid", and a "hybrid of a probe and DNA, said hybrid having a loop structure containing a microsatellite region and obtained by bringing a probe, which does not have a nucleotide sequence complementary to the microsatellite region and which will hybridize with the nucleotide sequences on both sides of the microsatellite region, into contact with DNA having the microsatellite region".
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
45.
METHOD FOR IDENTIFICATION AND DETECTION OF MUTANT GENE USING INTERCALATOR
The present invention addresses the problem of improving separation performance in separating a hybrid of a mutant DNA and a probe and/or a hybrid of a wild type DNA and a probe, said hybrids being obtained by the LH method. A method for the detection of a mutant DNA and/or a wild type DNA, said method comprising: step (1) for bringing into contact at least one kind of a single-stranded DNA (mutant DNA) having a substituted base, a deleted base region or an inserted base region, and/or a corresponding wild type single-stranded DNA (wild type DNA), with a probe that is hybridizable with both of the single stranded DNAs to form a hybrid (mutant hybrid) with the mutant DNA and/or a hybrid (wild type hybrid) with the wild type DNA, provided that the obtained mutant hybrid and/or wild-type hybrid have a loop structure; step (2) for bringing into contact the obtained mutant hybrid and/or wild type hybrid with an intercalator; and step (3) for separating a conjugate of the mutant hybrid with the intercalator and/or the conjugate of the wild-type hybrid with the intercalator to thereby detect the presence or absence of the mutant DNA and/or the wild type DNA.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
46.
CELL DIFFERENTIATION ASSAY METHOD, CELL ISOLATION METHOD, METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS, AND METHOD FOR PRODUCING DIFFERENTIATED CELLS
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japon)
WAKO PURE CHEMICAL INDUSTRIES, LTD. (Japon)
Inventeur(s)
Tateno, Hiroaki
Hirabayashi, Jun
Asashima, Makoto
Ito, Yuzuru
Onuma, Yasuko
Warashina, Masaki
Fukuda, Masakazu
Abrégé
Provided are a method for accurately evaluating the differentiation state of stem cells by selectively staining only undifferentiated stem cells, and a method for reliably isolating only undifferentiated stem cells. Specifically provided is a cell differentiation assay method including a step in which cells to be assayed are brought into contact with a probe comprising a protein described in (A) or (B), below, and a step in which the presence or absence of bonds between the probe and the cells to be assayed is detected on the basis of labels. The cell differentiation assay method is capable of detecting the presence or absence of undifferentiated stem cells among cells to be assayed by using a probe that specifically reacts with undifferentiated stem cells and detecting the presence or absence of bonds between the probe and the cells to be assayed. (A) A protein that includes the amino acid sequence represented by SEQ ID NO: 1 and recognizes the sugar chain structure of Fucα1-2Galβ1-3GlcNAc and/or Fucα1-2Galβ1-3GalNAc. (B) A protein that includes an amino acid sequence having a homology of at least 80% to the amino acid sequence represented by SEQ ID NO: 1 and recognizes the sugar chain structure of Fucα1-2Galβ1-3GlcNAc and/or Fucα1-2Galβ1-3GalNAc.
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
The present invention addresses the problem of providing a liquid crystal aligning agent which enables the formation of a liquid crystal alignment film that has high UV resistance and is thus not deteriorated even in a liquid crystal dropping method or the like that includes UV irradiation. The present invention relates to: (I) a compound represented by general formula [1] (wherein n represents an integer of 1-6, and R represents an alkyl group having 8-20 carbon atoms or a group having a steroid skeleton); (II) a polyamic acid or polyimide which is obtained by reacting (A) the above-mentioned compound represented by general formula [1], (B) a compound described below, and (C) a compound described below; and (III) a liquid crystal aligning agent which contains a polyamic acid or polyimide that is obtained by reacting the above-mentioned compounds (A), (B) and (C). (B) a compound represented by general formula [2] (wherein R1 represents an alkyl group having 1-6 carbon atoms or an arylalkyl group having 7-12 carbon atoms, p represents an integer of 0-6, and Y represents an amino group or a 4-aminophenyl group) (C) a compound represented by general formula [3] or [4] (wherein Z represents a tetravalent hydrocarbon group)
C07J 9/00 - Stéroïdes normaux contenant du carbone, de l'hydrogène, un halogène ou de l'oxygène, substitués en position 17bèta par une chaîne de plus de deux atomes de carbone, p. ex. cholane, cholestane, coprostane
C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
G02F 1/1337 - Orientation des molécules des cristaux liquides induite par les caractéristiques de surface, p. ex. par des couches d'alignement
48.
METHOD FOR DETECTING METHYLATED CYTOSINE BY USING BISULFITE REACTION
The present invention addresses the problem of providing: a method for converting the non-methylated cytosine within a single-stranded DNA into uracil by means of a novel bisulfite reaction in which the conversion rate from non-methylated cytosine to uracil is higher compared to conventional bisulfite methods; a method for amplifying the single-stranded DNA in which the non-methylated cytosine is converted into uracil; and a method for detecting the methylated cytosine in the single-stranded DNA. The present invention pertains to: "(1) a method for converting the non-methylated cytosine within a single-stranded DNA into uracil, wherein the single-stranded DNA is characterized by being subjected to a bisulfite reaction in the presence of at least one compound represented by general formulae [1] to [8]; (2) a method for amplifying the single-stranded DNA in which the non-methylated cytosine is converted into uracil, wherein the single-stranded DNA is subjected to a PCR reaction after being subjected to the bisulfite reaction in (1); and (3) a method for detecting the methylated cytosine in the single-stranded DNA, wherein the single-stranded DNA amplified in (2) is subjected to a base sequence analysis".
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
The present invention addresses the problem of providing a method for producing an organic triol borate salt, the method being capable of producing an organic triol borate salt that contains functional groups such as a carbonyl oxy group, a carbonyl group, a hydroxyl group, and an amino group. The present invention relates to: (I) a method for producing an organic triol borate salt represented by general formula [3] [3] characterized by reacting a compound represented by general formula [1] [1] with a compound represented by general formula [2] [2] in an organic solvent under the presence of water and alkali metal hydroxide (MOH); and (II) an organic triol borate salt represented by general formula (3'). [3']
An objective of the present invention is to provide a practical production method in consideration of reducing environmental load, which can produce cyclic carbonate at a good yield under mild conditions such as room temperature and atmospheric pressure, and in which cyclic carbonate, which is widely used for various purposes such as, for example, an electrolyte for lithium ion secondary batteries and raw materials for plastic, is produced through a reaction of epoxide (oxirane) and carbon dioxide. The present invention relates to a method for producing cyclic carbonate, characterized by reacting epoxide and carbon dioxide with an amine compound in the presence of hydrogen iodide, wherein the amine compound is selected, as a primary to tertiary amine having a pKa of 8 or more, from monoamine, cyclic amidine, and guanidine.
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japon)
WAKO PURE CHEMICAL INDUSTRIES, LTD. (Japon)
Inventeur(s)
Tateno, Hiroaki
Hirabayashi, Jun
Ito, Yuzuru
Onuma, Yasuko
Asashima, Makoto
Kuno, Atsushi
Warashina, Masaki
Fukuda, Masakazu
Abrégé
Provided is a method for evaluating the state of cell differentiation using a conditioned medium in which stem cells are being cultured. This invention is capable of providing an "undifferentiated sugar chain marker" comprising a "Fucα1-2Galβ1-3GlcNAc" or "Fucα1-2Galβ1-3GalNAc" sugar chain structure, with which it is possible to identify, with a high degree of accuracy, the state of differentiation of stem cells, using a stem cell conditioned medium. At the same time, it was discovered that BC2LCN lectin or a variant thereof, which can recognize said "undifferentiated sugar chain marker" with a high degree of accuracy, is an outstanding "detection probe for undifferentiated sugar chain markers" which can identify the undifferentiated state of cells in a conditioned medium.
C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
The purpose of the present invention is to provide an electrochemical device that comprises a highly safe electrolyte solution which has high current density and high oxidation resistance and wherein dissolution and precipitation of magnesium are stably repeated. The present invention relates to: an electrolyte solution for electrochemical devices, which comprise (1) a supporting electrolyte that is composed of a magnesium salt and (2) at least one compound represented by general formula [2]; and an electrochemical device which comprises the electrolyte solution, a positive electrode, a negative electrode and a separator.
An external standard solution for use in the analysis of an amino acid in plasma, comprising: (1) one or more amino acids independently selected from the components (A) mentioned below each at a concentration of 0.0007 to 0.49 M; and (2) (i) one or more amino acids independently selected from the components (B) mentioned below each at a concentration of 0.2 to 0.9 time smaller than that of an amino acid that is contained at the lowest concentration among the amino acids independently selected from the components (A), (ii) one or more amino acids independently selected from the components (C) mentioned below each at a concentration of 0.1 to 0.4 time smaller than that of an amino acid that is contained at the lowest concentration among the amino acids independently selected from the components (A), or (iii) one or more amino acids independently selected from the components (D) mentioned below each at a concentration of 0.05 to 0.2 time smaller than that of an amino acid that is contained at the lowest concentration among the amino acids independently selected from the components (A): [the components (A)] valine, glycine, alanine and glutamine; [the components (B)] serine, proline, threonine, taurine, leucine, isoleucine, lysine, histidine, phenylalanine and tyrosine; [the components (C)] asparagine, ornithine, arginine and tryptophan; and [the components (D)] glutamic acid, methionine, citrulline and cystine.
G01N 30/04 - Préparation ou injection de l'échantillon à analyser
G01N 27/62 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'ionisation des gaz, p. ex. des aérosolsRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant les décharges électriques, p. ex. l'émission cathodique
G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
54.
ASSAY METHOD USING MAGNETIC SILICA PARTICLES AND REAGENT FOR SAID ASSAY METHOD
This assay method is characterized in that an analyte substance contained in a sample is measured using specific magnetic silica particles, namely, silica particles which contain 60 to 95wt% of a superparamagnetic metal oxide having a mean particle diameter of 1 to 15nm and on the surfaces of which the analyte substance, an analogue thereof, or a substance capable of bonding specifically to the analyte substance is immobilized.
G01N 33/553 - Support métallique ou recouvert d'un métal
C01B 33/12 - SiliceSes hydrates, p. ex. acide silicique lépidoïque
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
The purpose of the present invention is to provide an agglutination enhancer which has a superior agglutination enhancing effect to those of conventional immunoagglutination enhancers. An agglutination enhancer for use in an immunoagglutination measurement method, which comprises a polymer having a monomer unit represented by general formula [1] (wherein R1 represents a hydrogen atom or a methyl group; R2 and R3 independently represent a methyl group or an ethyl group; X represents -NH-or an oxygen atom; n represents an integer of 1-6; and m represents an integer of 1-3): and an immunoagglutination measurement method comprising bringing an antibody against an analyte (a substance to be measure) or an antigen for the analyte into contact with the analyte in the co-presence of the above-mentioned agglutination enhancer for use in an immunoagglutination measurement method to thereby cause an antigen-antibody reaction.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
C08F 20/36 - Esters contenant de l'azote contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle
C08F 20/60 - Amides contenant de l'azote en plus de l'azote de la fonction carbonamide
C08F 220/36 - Esters contenant de l'azote contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle
C08F 220/60 - Amides contenant de l'azote en plus de l'azote de la fonction carbonamide
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/573 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour enzymes ou isoenzymes
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
The purpose of the present invention is to provide an intermediate which is suitable for the synthesis of a fluorinated liquid crystalline compound. The present invention relates to a compound represented by general formula [1] [wherein one of R1 and R2 represents a hydrogen atom and the other represents a group represented by general formula [2] (wherein T1 represents a C1-10 alkylene chain which may have an oxygen atom, a carbon-carbon double bond or/and a carbon-carbon triple bond therein), wherein R1, R2 and a carbon atom adjacent to R1 and R2 may together form a group represented by general formula [3] (wherein T2 represents a C1-9 alkylene chain which may have an oxygen atom, a carbon-carbon double bond or/and a carbon-carbon triple bond therein); one of R3 and R4 represents a hydrogen atom and the other represents a hydroxy group, each of R3 and R4 represents an alkoxy group, or R3, R4 and a carbon atom adjacent to R3 and R4 together form a group represented by formula [4] or general formula [5] (in general formula [5], n represents 1 or 2)].
C07C 43/196 - Éthers une liaison sur l'oxygène de la fonction éther étant sur un atome de carbone d'un cycle autre que ceux d'un cycle aromatique à six chaînons contenant des groupes hydroxyle ou O-métal
C07C 49/457 - Composés saturés comportant un groupe cétone faisant partie d'un cycle contenant des atomes d'halogène
C07C 49/517 - Composés saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes éther, des groupes , des groupes ou des groupes
C07C 49/687 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des atomes d'halogène
C07D 317/72 - Composés hétérocycliques contenant des cycles à cinq chaînons comportant deux atomes d'oxygène comme uniques hétéro-atomes du cycle comportant les hétéro-atomes en positions 1, 3 condensés en spiro avec des carbocycles
57.
PARTIAL HYDROGENATION REACTION OF ALKYNE DERIVATIVE
The invention relates to a method for producing an alkene derivative represented by general formula [4] (wherein R1 represents an aryl group having, as a substitute, an alkyl group, an alkoxy group, a halogen atom, an amino group, or a nitro group, an aryl group having no substituent, or an alkyl group; and R2 represents a hydrogen atom, an alkyl group, a hydroxyalkyl group or an alkoxycarbonyl group), characterized by comprising reducing an alkyne derivative represented by general formula [1] (wherein R1 and R2 are the same as above) by bringing the alkyne derivative into contact with a hydrogen source in the presence of (I) silica or titanium oxide, which supports palladium having a particle diameter of 0.3 to 10 nm, and a sulfur compound represented by general formula [2] (wherein R3 and R4 each independently represent an alkyl group or an aryl group) or/and general formula [3] (wherein R5 and R6 each independently represent an alkyl group or an aryl group) in an amount 1 to 1000 times the mole of palladium, or in the presence of (II) silica or titanium oxide, which supports palladium having a particle diameter of 0.3 to 10 nm and has a sulfoxide group.
C07C 5/09 - Préparation d'hydrocarbures à partir d'hydrocarbures contenant le même nombre d'atomes de carbone par hydrogénation de liaisons triples carbone-carbone en liaisons doubles carbone-carbone
C07C 13/20 - Hydrocarbures monocycliques ou leurs dérivés hydrocarbonés acycliques à cycle hexagonal à cycle du cyclohexène
C07C 15/44 - Hydrocarbures cycliques ne contenant que des cycles aromatiques à six chaînons en tant que partie cyclique substitués par des radicaux hydrocarbonés non saturés monocycliques le substituant hydrocarboné contenant une liaison double carbone-carbone
C07C 17/354 - Préparation d'hydrocarbures halogénés par des réactions n'influençant pas le nombre d'atomes de carbone ou d'halogène dans les molécules par hydrogénation
C07C 29/17 - Préparation de composés comportant des groupes hydroxyle ou O-métal liés à un atome de carbone ne faisant pas partie d'un cycle aromatique à six chaînons par hydrogénation de liaisons doubles ou triples carbone-carbone
C07C 33/025 - Alcools acycliques à liaisons doubles carbone-carbone à une seule liaison double
C07C 33/03 - Alcools acycliques à liaisons doubles carbone-carbone à une seule liaison double en position bêta, p. ex. alcool allylique, alcool méthallylique
C07C 41/20 - Préparation d'éthers par des réactions ne formant pas de liaisons sur l'oxygène de la fonction éther par hydrogénation de liaisons doubles ou triples carbone-carbone
C07C 43/215 - Éthers une liaison sur l'oxygène de la fonction éther étant sur un atome de carbone d'un cycle aromatique à six chaînons avec une insaturation autre que celle des cycles aromatiques à six chaînons
C07C 67/303 - Préparation d'esters d'acides carboxyliques par modification de la partie acide de l'ester sans introduction d'un groupe ester par hydrogénation de liaisons non saturées carbone-carbone
C07C 69/618 - Esters d'acides carboxyliques avec un groupe carboxyle lié à un atome de carbone acyclique et comportant un cycle aromatique à six chaînons dans la partie acide avec insaturation autre que celle du cycle aromatique à six chaînons
C07C 201/14 - Préparation de composés nitrés par formation de groupes nitro combinée avec des réactions ne créant pas de groupes nitro
C07C 205/06 - Composés contenant des groupes nitro liés à un squelette carboné ayant des groupes nitro liés à des atomes de carbone de cycles aromatiques à six chaînons
C07C 209/70 - Préparation de composés contenant des groupes amino liés à un squelette carboné à partir d'amines, par des réactions n'impliquant pas de groupes amino, p. ex. réduction d'amines non saturées, aromatisation ou substitution du squelette carboné par réduction d'amines non saturées
The present invention provides a method for acquiring a bisulfite-treated DNA capable of preserving a gene library unchanged and having superior preservation stability, and also provides a method for detecting methylated cytosine with greater precision than a conventional bisulfate technique. More specifically, the present invention relates to a method for acquiring DNA which is complementary to single-strand DNA and in which non-methylated cytosine is converted to uracil, characterized by subjecting the single-strand DNA to (1) a bisulfite reaction and (2) a reverse transcriptase reaction in this order; to a method for amplifying DNA which is complementary to single-strand DNA and in which non-methylated cytosine is converted to uracil, characterized by subjecting the single-strand DNA to (1) a bisulfite reaction, (2) a reverse transcriptase reaction, and (3) a PCR reaction in this order; and a method for detecting methylated cytosine in single-strand DNA, characterized by subjecting the single-strand DNA to (1) a bisulfite reaction, (2) a reverse transcriptase reaction, and (3) a PCR reaction, and performing a base sequence analysis on the resulting amplification product of the PCR.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
59.
SUBSTRATE CLEANER FOR COPPER WIRING, AND METHOD FOR CLEANING COPPER WIRING SEMICONDUCTOR SUBSTRATE
The present invention addresses the problems of: providing a substrate cleaner for copper wiring which sufficiently suppresses the elution of metal copper during the cleaning of a semiconductor substrate after the chemical mechanical polishing (CMP) step in a process for manufacturing the semiconductor substrate, and which permits the removal of particles and impurities such as copper (II) hydroxide and copper (II) oxide generated during the chemical mechanical polishing step (CMP); and of providing a method for cleaning a copper wiring semiconductor substrate characterized by the use of this substrate cleaner for copper wiring. The present invention relates to a substrate cleaner for copper wiring comprising an aqueous solution containing [I] an amino acid represented by General Formula (1), and [II] an alkylhydroxylamine; and to a method for cleaning a copper wiring semiconductor substrate characterized by the use of this substrate cleaner for copper wiring. (In the formula, R1 represents a hydrogen atom, a carboxymethyl group, or a carboxyethyl group; and R2 and R3 each independently represent a hydrogen atom, or a C1-4 alkyl group which may have a hydroxyl group. R1 to R3 cannot all be hydrogen atoms.)
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japon)
Inventeur(s)
Kikuchi Nobuyuki
Takato Hidetaka
Sakata Isao
Abrégé
The purpose is to provide a process for easily producing at low cost a silicon substrate for use in solar cell production and an acidic etchant for silicon wafers. In the process, uniform irregularities suitable for solar cells are formed in a surface of a wafer of polycrystalline silicon to thereby make a contribution to an improvement in photoelectric conversion efficiency due to the resultant reduction in reflectance, and the polycrystalline-silicon wafer is prevented from staining when etched. This process for producing a silicon substrate for solar cell production is characterized by etching a silicon wafer with an acidic etchant comprising (a) at least one compound selected from the group consisting of halooxoacids and salts thereof, (b) at least one compound selected from the group consisting of hydrogen fluoride and salts thereof, (c) nitric acid and/or hydrogen peroxide, and (d) water to thereby form irregularities in the surface of the silicon wafer. The acidic etchant for silicon wafers comprises the ingredients (a) to (d).
H01L 31/04 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV]
H01L 21/308 - Traitement chimique ou électrique, p. ex. gravure électrolytique en utilisant des masques
The purpose of the present invention is to provide: a substrate etching agent that does not cause over-etching, etching residue, etching inconsistencies, or the like when selectively etching a silicon nitride (SiN) film formed in the process of manufacturing a semiconductor substrate, for example, and is particularly effective in spin etching, which allows selective etching of just a silicon nitride (SiN) film without etching a silicon oxide (SiO) film; and a substrate etching method characterized by having a step wherein the aforementioned substrate etching agent is used to etch a silicon nitride (SiN) film on a substrate. The present invention pertains to: a substrate etching agent that comprises (I) phosphoric acid, (II) a fluorine anionic surfactant that contains no ether linkages, and (III) water; and a substrate etching method characterized by having a step in which said substrate etching agent is used to etch a silicon nitride (SiN) film on a substrate.
The purpose of the present invention is to provide a method which can be used for high-throughput applications and enables the easy and highly efficient acquisition of small RNA. The present invention relates to a method for acquiring small RNA, which is characterized by bringing a carrier having, immobilized on the surface thereof, a substance having an affinity for a small RNA-binding protein into contact with a complex of the small RNA-binding protein and the small RNA (a protein-RNA complex) to thereby bind the protein-RNA complex to the carrier and heating the carrier to which the protein-RNA complex has been bound at 70-100˚C in water or a buffering solution having a pH value of 3.0-8.0 to cause the release of the small RNA, thereby obtaining the small RNA.
The present invention relates to a method for detecting mutant DNA using a probe, and is characterized in comprising the steps of: (1) bringing into contact a sample containing single-stranded DNA (mutant DNA) having a substituted base, a deleted base region, or an inserted base region, and/or containing a corresponding wild-type single-stranded DNA (wild-type DNA), and a probe for hybridization with both of the single stranded DNAs, and forming a hybrid (mutant hybrid) with the mutant DNA and/or a hybrid (wild-type hybrid) with the wild-type DNA, the obtained mutant hybrid and/or wild-type hybrid having a stem structure; (2) separating the obtained mutant hybrid and/or wild-type hybrid by electrophoresis according to the presence or absence of the stem structure or differences in the stem structures; and (3) detecting the presence or absence of the mutant DNA in the sample.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
The purpose of the present invention is to provide: a composition which can be used for water-repellent-treating the entire surface of a semiconductor substrate having a pattern formed by laminating an Si-containing insulating layer and a metal layer, at one time; and a method for the water-repellent treatment of the surface of the semiconductor substrate using the composition. The present invention relates to: (1) a composition for the water-repellent treatment of the surface of a semiconductor substrate, which comprises a) at least one compound selected from the group consisting of a long-chain alkyl tertiary amine and a long-chain alkyl ammonium salt, b) a base or acid generator which has a fused ring structure or can generate a base or an acid to form a fused ring structure and c) a polar organic solvent; and (2) a method for the water-repellent treatment of the surface of a semiconductor substrate having a pattern formed by laminating an Si-containing insulating layer and a metal layer, which uses the composition.
H01L 21/304 - Traitement mécanique, p. ex. meulage, polissage, coupe
C09K 3/18 - Substances non couvertes ailleurs à appliquer sur des surfaces pour y minimiser l'adhérence de la glace, du brouillard ou de l'eauSubstances antigel ou provoquant le dégel pour application sur des surfaces
65.
NONAQUEOUS ELECTROLYTE SOLUTION, METHOD FOR PRODUCING SAME, AND NONAQUEOUS ELECTROLYTE BATTERY USING THE ELECTROLYTE SOLUTION
[Problem] To provide: a novel nonaqueous electrolyte solution which uses a methylene bissulfonate derivative, reduces the initial irreversible capacity of a battery, and improves battery characteristics such as cycle characteristics, electric capacity and storage characteristics; a method for producing the nonaqueous electrolyte solution; and a battery which uses the electrolyte solution. [Solution] The present invention relates to the following <1>-<3>. <1> A nonaqueous electrolyte solution which contains the following (1)-(3). (1) A nonaqueous solvent which contains at least one ester selected from among cyclic carbonate esters, chain carbonate esters and cyclic carboxylic acid esters. (2) A lithium salt which can be dissolved as an electrolyte salt into the nonaqueous solvent. (3) A methylene bissulfonate derivative which is represented by general formula [I]. <2> A method for producing a nonaqueous electrolyte solution, which is characterized in that a lithium salt is dissolved in a nonaqueous solvent and then the methylene bissulfonate derivative is dissolved in the nonaqueous solvent. <3> A nonaqueous electrolyte battery which comprises (i) the nonaqueous electrolyte solution set forth in <1>, (ii) a negative electrode, (iii) a positive electrode and (iv) a separator.
H01M 10/0567 - Matériaux liquides caracterisés par les additifs
H01M 2/16 - Séparateurs; Membranes; Diaphragmes; Eléments d'espacement caractérisés par le matériau
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
H01M 4/48 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p. ex. LiTi2O4 ou LiTi2OxFy
H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p. ex. LiMn2O4 ou LiMn2OxFy
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p. ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
H01M 4/587 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
[Problem] To provide: a novel nonaqueous electrolyte solution which uses a methylene bissulfonate derivative, reduces the initial irreversible capacity of a battery, and improves battery characteristics such as cycle characteristics, electric capacity and storage characteristics; a method for producing the nonaqueous electrolyte solution; and a battery which uses the electrolyte solution. [Solution] The present invention relates to the following <1>-<3>. <1> A nonaqueous electrolyte solution which contains the following (1)-(3). (1) A nonaqueous solvent which contains at least one ester selected from among cyclic carbonate esters, chain carbonate esters and cyclic carboxylic acid esters. (2) A lithium salt which can be dissolved as an electrolyte salt into the nonaqueous solvent. (3) A methylene bissulfonate derivative which is represented by general formula [1]. <2> A method for producing a nonaqueous electrolyte solution, which is characterized in that a lithium salt is dissolved in a nonaqueous solvent and then the methylene bissulfonate derivative is dissolved in the nonaqueous solvent. <3> A nonaqueous electrolyte battery which comprises (i) the nonaqueous electrolyte solution set forth in <1>, (ii) a negative electrode, (iii) a positive electrode and (iv) a separator.
H01M 10/0567 - Matériaux liquides caracterisés par les additifs
H01M 2/16 - Séparateurs; Membranes; Diaphragmes; Eléments d'espacement caractérisés par le matériau
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
H01M 4/48 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p. ex. LiTi2O4 ou LiTi2OxFy
H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p. ex. LiMn2O4 ou LiMn2OxFy
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p. ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
H01M 4/587 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
A process for the deuteration or tritiation of a saccharide, characterized in that a saccharide which contains a furanose or pyranose constituent component wherein no hydroxyl group is bonded to any carbon atom bonded to the oxygen atom of the tetrahydrofuran or teterahydropyran ring and a hydroxyl group is bonded to at least one of the other carbon atoms is reacted with a deuterated or tritiated solvent in the presence of a ruthenium catalyst and hydrogen gas to replace selectively a hydrogen atom bonded to the carbon atom which a hydroxyl group is directly bonded to by a deuterium or tritium atom.
Disclosed are: an oligonucleotide that is designed on the basis of the base sequences represented by sequence number 1 and sequence number 2, and that hybridizes with an endogenous plasmid gene of Chlamydia trachomatis ; an oligonucliotide primer and probe for detecting Chlamydia trachomatis; a method for detecting Chlamydia trachomatis using said primer and probe; and the use of said oligonucleotide for designing the primer or probe for detecting Chlamydia trachomatis.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
Disclosed is a process for efficiently producing a deuteride of a compound that has a fused ring structure having a naphthalene skeleton, a carbazole skeleton or a heterocyclic ring skeleton analogous to the aforementioned skeletons. Specifically disclosed is a process for producing a deuteride represented by, for example, general formula [6], which is characterized by comprising reacting a compound represented by, for example, general formula [1] with a deuterated solvent in the co-presence of a catalyst selected from a palladium catalyst, a platinum catalyst, a nickel catalyst, a cobalt catalyst, an iridium catalyst, a rhodium catalyst and a ruthenium catalyst.
C07C 5/367 - Formation d'un cycle aromatique à six chaînons à partir d'un cycle à six chaînons existant, p. ex. déshydrogénation de l'éthylcyclohexane en éthylbenzène
C07C 15/24 - Hydrocarbures polycycliques condensés contenant deux cycles
C07D 209/86 - CarbazolesCarbazoles hydrogénés avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du système cyclique
C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
Disclosed are: a resist remover composition for semiconductor substrates, which is capable of simply and easily removing a resist in a photolithography process in semiconductor fields; and a method for removing a resist, which is characterized by using the resist remover composition. Specifically disclosed is a resist remover composition for semiconductor substrates, which is characterized by containing (I) a carbon radical generator, (II) an acid, (III) a reducing agent and (IV) an organic solvent, and having a pH of less than 7. Also specifically discloses is a method for removing a resist, which is characterized by using the resist remover composition.
Disclosed are: a processing agent composition for semiconductor surfaces, which is capable of easily removing an antireflective film layer, a resist layer and a resist cured layer in a short time during the production procedure of a semiconductor element or the like; and a method for processing a semiconductor surface, which is characterized by using the processing agent composition. Specifically disclosed is a processing agent composition for semiconductor surfaces, which is characterized by containing (I) a compound which generates fluorine ions in water, (II) a carbon radical generator, (III) water, (IV) an organic solvent and (V) at least one compound selected from the group consisting of hydroxylamines and hydroxylamine derivatives represented by general formula (1). Also specifically discloses is a method for processing a semiconductor surface, which is characterized by using the processing agent composition. (In the formula, R1 represents a linear, branched or cyclic alkyl group with 1-6 carbon atoms or a linear or branched substituted alkyl group with 1-4 carbon atoms having 1-3 hydroxyl groups; and R2 represents a hydrogen atom, a linear, branched or cyclic alkyl group with 1-6 carbon atoms or a linear or branched substituted alkyl group with 1-4 carbon atoms having 1-3 hydroxyl groups.)
Disclosed is a novel ionic liquid which can be produced at low cost, is safe for the environment, and has a low viscosity and a low melting point. Specifically disclosed is an ionic liquid represented by general formula [1] (wherein R1 to R3 and n R4s independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; R5 to R7 independently represent an alkyl group, an aralkyl group or an allyl group; R8 represents an alkyl group, an aralkyl group, an allyl group, or a group represented by general formula [2] (wherein T represents an alkylene chain having 1 to 8 carbon atoms; and R1 to R7 and n are as defined above); X represents a nitrogen atom or a phosphorus atom; and n represents 1 or 2, wherein R3 and R4 may be bound to each other to, together with an adjacent carbon atom, form a cyclohexene ring when n is 1, and R5 to R7 or R5 to R6, together with a nitrogen atom to which these groups are bound, may form a heteroring when n is a nitrogen atom).
C07C 309/20 - Acides sulfoniques ayant des groupes sulfo liés à des atomes de carbone acycliques d'un squelette carboné acyclique non saturé
C07D 213/06 - Composés hétérocycliques contenant des cycles à six chaînons, non condensés avec d'autres cycles, ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle et avec au moins trois doubles liaisons entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques comportant trois liaisons doubles ne comportant pas de liaison entre l'atome d'azote du cycle et un chaînon non cyclique ou ne comportant que des atomes d'hydrogène ou de carbone liés directement à l'atome d'azote du cycle contenant uniquement des atomes d'hydrogène et de carbone en plus de l'atome d'azote du cycle
C07D 213/68 - Un atome d'oxygène lié en position 4
C07D 233/58 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, non condensés avec d'autres cycles comportant deux liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène ou des radicaux ne contenant que des atomes d'hydrogène et de carbone, liés aux atomes de carbone du cycle avec uniquement des atomes d'hydrogène ou des radicaux ne contenant que des atomes d'hydrogène et de carbone, liés aux atomes d'azote du cycle
C07D 295/04 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de carbone du cycle avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle
C07D 295/08 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de carbone du cycle avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes d'oxygène ou de soufre liés par des liaisons simples
73.
PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE
Disclosed are: a process for producing a bis-quaternary ammonium salt with high efficiency; and a novel synthetic intermediate for the process. Specifically disclosed are: a process for producing a bis-quaternary ammonium salt represented by general formula [3], which is characterized by reacting a disulfonic acid ester represented by general formula [1] (wherein two R1's and T are as defined in claim 1) with a tertiary amine represented by general formula [2] (wherein R3 to R5 are as defined in claim 1); and a disulfonic acid ester represented by general formula [1'] (wherein two R16's independently represent a halogen atom, or a fluoroalkyl group having 1 to 3 carbon atoms; and two m's independently represent an integer of 1 to 5).
C07C 209/20 - Préparation de composés contenant des groupes amino liés à un squelette carboné par substitution de groupes fonctionnels par des groupes amino par substitution de groupes hydroxy ou de groupes hydroxy éthérifiés ou estérifiés avec formation de composés d'ammonium quaternaire
C07C 211/63 - Composés d'ammonium quaternaire ayant des atomes d'azote quaternisés liés à des atomes de carbone acycliques
C07C 303/32 - Préparation d'esters ou d'amides d'acides sulfuriquesPréparation d'acides sulfoniques ou de leurs esters, halogénures, anhydrides ou amides de sels d'acides sulfoniques
C07C 309/73 - Esters d'acides sulfoniques ayant des atomes de soufre de groupes sulfo estérifiés liés à des atomes de carbone de cycles aromatiques à six chaînons d'un squelette carboné à des atomes de carbone de cycles aromatiques à six chaînons non condensés
C07D 213/06 - Composés hétérocycliques contenant des cycles à six chaînons, non condensés avec d'autres cycles, ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle et avec au moins trois doubles liaisons entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques comportant trois liaisons doubles ne comportant pas de liaison entre l'atome d'azote du cycle et un chaînon non cyclique ou ne comportant que des atomes d'hydrogène ou de carbone liés directement à l'atome d'azote du cycle contenant uniquement des atomes d'hydrogène et de carbone en plus de l'atome d'azote du cycle
C07D 213/127 - Préparation à partir de composés renfermant des cycles pyridiniques
C07D 233/64 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, non condensés avec d'autres cycles comportant deux liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des radicaux hydrocarbonés substitués, liés aux atomes de carbone du cycle, p. ex. histidine
74.
METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF
Provided is an efficient production method which makes it possible to obtain a cyclic sulfonic acid ester (sultone) not only at a low cost and with a high yield but also stably on an industrial scale. Specifically disclosed are: a method for producing hydroxysultone, which includes a first step in which a diol having a specific structure is reacted with a thionyl halide to obtain a cyclic sulfite ester having a specific structure, and a second step in which the cyclic sulfite ester is reacted with water and/or alcohol; a method for producing an unsaturated sultone having a specific structure, which includes a third step in which hydroxysultone having a specific structure is reacted with an acid halide or acid anhydride to obtain an intermediate, and then the intermediate is treated with a base; and a cyclic sulfite ester having a specific structure.
C07D 327/10 - Composés hétérocycliques contenant des cycles comportant des atomes de soufre et d'oxygène comme uniques hétéro-atomes du cycle deux atomes d'oxygène et un atome de soufre, p. ex. sulfates cycliques
Disclosed is a method for purifying a compound selected from a compound represented by formula [1] or [2], a saturated aliphatic hydrocarbon which has no substituent, and kerosene, characterized by removing impurities contained in the compound through a first step of bringing the compound into contact with ozone gas, and then a second step of bringing the compound into contact with an adsorbent selected from a zeolite and a basic adsorbent. In formula [1], R represents a halogen atom or a lower alkyl group having 1 to 3 carbon atoms, and n represents an integer of 1 to 5. In formula [2], R is the same as above, and p and q each independently represent an integer of 0 to 4, however, at least one of p and q is not 0.
C07C 7/12 - Purification, séparation ou stabilisation d'hydrocarburesEmploi d'additifs par adsorption, c.-à-d. purification ou séparation d'hydrocarbures à l'aide de solides, p. ex. à l'aide d'échangeurs d'ions
C07C 7/148 - Purification, séparation ou stabilisation d'hydrocarburesEmploi d'additifs par traitement provoquant une modification chimique d'au moins un composé
Disclosed are: a method for synthesizing double-stranded DNA from corresponding specific RNA at low cost and in a simple manner; and a method for amplifying the double-stranded DNA. Specifically disclosed are: a method for synthesizing double-stranded DNA having a nucleotide sequence corresponding to template RNA having a poly-A attached thereto, which is characterized by comprising step 1 of carrying out a reverse transcription reaction of the template RNA having a poly-A attached thereto using an oligo (dT) primer having, added to the 5'-terminal thereof, a DNA fragment having a known sequence to thereby obtain single-stranded DNA and step 2 of carrying out a double-strand formation reaction of the single-stranded DNA obtained in step 1 using a random primer having, added to the 5'-terminal thereof, a DNA fragment having a known sequence in the presence of a polymerase that does not have a 3'→5' exonuclease activity and a chain substitution activity to thereby obtain double-stranded DNA; and a method for amplifying double-stranded DNA having a nucleotide sequence corresponding to template RNA having a poly-A attached thereto, which is characterized by comprising step 3 of carrying out a PCR reaction using the double-stranded DNA.
A compound represented by general formula [1] or a salt thereof, which is a novel cyanine dye derivative having a high fluorescence intensity in a short-wavelength region. The cyanine dye derivative has a structure comprising a pyrazole skeleton and an indole skeleton combined therewith through a polymethine chain, and has been rendered controllable with respect to electrophoretic mobility by further introducing a quaternary ammonium cation into a molecule having that structure. (In formula [1], R1 to R6 each independently represents, for example, an alkyl having a substituent represented by general formula [101], R7 to R10 each independently represents a hydrogen atom, etc., R11 represents a hydrogen atom, an alkyl, etc., and n is an integer of 0-3, at least one of R1 to R6 being an alkyl having a substituent represented by general formula [101].)
C07D 403/06 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée ne contenant que des atomes de carbone aliphatiques
C09B 23/00 - Colorants méthiniques ou polyméthiniques, p. ex. du type cyanine
G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur
78.
MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE
Disclosed is a method for measuring an analyte utilizing an internal standard substance, which can be used in an electrophoresis method in which the analyte is a protein or a compound. Specifically disclosed is a method for measuring an analyte by an electrophoresis method, which is characterized by identifying the peak of the analyte using, as an internal standard substance, (1) a combination of a compound having at least three anionic groups in the molecule and a compound produced by substituting 1 to 3 anionic groups in the aforementioned compound by cationic groups or (2) a combination of a compound having at least three cationic groups in the molecule and a compound produced by substituting 1 to 3 cationic groups in the aforementioned compound by anionic groups.
Disclosed are: a method for measuring βG, which comprises bringing a sample into contact with a βG-binding protein 1 and a βG-binding protein 2 to form a complex of the βG-binding protein 1, βG in the sample and the βG-binding protein 2, measuring the quantity of the complex, and determining the quantity of βG in the sample based on the quantity of the complex, wherein each of the βG-binding protein 1 and the βG-binding protein 2 comprises an amino acid sequence which is identical or substantially identical to an amino acid sequence depicted in any one of SEQ ID NO:4, SEQ ID NO:6, SEQ ID NO:8, SEQ ID NO:10, SEQ ID NO:14, SEQ ID NO:16, SEQ ID NO:18 and SEQ ID NO:20 and is capable of binding to βG; a reagent and a kit for use in the method; a novel βG-binding protein; a nucleic acid molecule encoding the βG-binding protein; and a method for producing the βG-binding protein.
G01N 33/579 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir un lysat de limulus
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
C12N 1/15 - ChampignonsLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 1/21 - BactériesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p. ex. glutathion
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
Provided are novel compounds which generate bases easily when irradiated with long-wavelength light (active energy rays), a photobase generator containing the compounds, and a photobase generation method. Disclosed are compounds represented by general formula (1), a photobase generator containing the compounds, and a photobase generation method. (In the formula, Ar represents a group with a specific structure selected from a group comprising an anthracenyl group, an anthraquinonyl group and a pyrenyl group; R1 and R2 independently represent a hydrogen atom or a straight-chain, branched, or cyclic alkyl group with carbon number 1-10, or they represent a group which forms a nitrogen-containing aliphatic ring or a nitrogen-containing aromatic ring with carbon number 3-8 which may have a substituent along with a nitrogen atom to which said group is bonded; and R3 and R4 independently represent a hydrogen atom or a straight-chain, branched, or cyclic alkyl group with carbon number 1-10.)
C07C 271/12 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec les atomes d'azote des groupes carbamate liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués
C07D 233/60 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, non condensés avec d'autres cycles comportant deux liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène ou des radicaux ne contenant que des atomes d'hydrogène et de carbone, liés aux atomes de carbone du cycle avec des radicaux hydrocarbonés, substitués par des atomes d'oxygène ou de soufre, liés aux atomes d'azote du cycle
C07D 295/20 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de carbone du cycle acylés sur les atomes d'azote du cycle par des radicaux dérivés de l'acide carbonique ou de ses analogues du soufre ou de l'azote
Novel compounds which readily generate a base upon irradiation with long-wavelength light (actinic energy rays), a photo-base generator comprising any of these compounds, and a method of generating a base. The compounds are represented by general formula [I]. (In formula [I], R1 and R2 each independently represents hydrogen or a liner, branched, or cyclic C1-10 alkyl group, or R1 and R2 form an optionally substituted C3-8 nitrogenous aliphatic ring or nitrogenous aromatic ring in cooperation with the nitrogen atom bonded thereto; R3 and R4 each independently represents hydrogen, a linear, branched, or cyclic C1-10 alkyl group, or optionally substituted phenyl; and R5, R6, R7, and R8 each independently represents hydrogen or a linear, branched, or cyclic C1-10 alkyl group.)
C07D 335/16 - Atomes d'oxygène, p. ex. thioxanthones
C07D 409/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
A reaction container provided with a flow path and a containing section communicating with the flow path and containing liquid introduced into the flow path, wherein, without water repellent surface treatment, the liquid in the containing section is easily prevented from rising to an opening surface by a capillary effect. A reaction container (1) provided with a flow path (3) and a containing section (2) for containing liquid (F) introduced into the flow path (3), wherein the containing section (2) has formed therein a large-diameter section (24) located above a step (22). The step (22) has a size preventing the liquid (F) contained in the containing section (2) below the step (22) from rising to a level above the step (22) by a capillary effect.
G01N 35/08 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant un courant d'échantillons discrets circulant dans une canalisation, p. ex. analyse à injection dans un écoulement
B01J 19/00 - Procédés chimiques, physiques ou physico-chimiques en généralAppareils appropriés
B81B 1/00 - Dispositifs sans éléments mobiles ou flexibles, p. ex. dispositifs capillaires microscopiques
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
G01N 37/00 - Détails non couverts par les autres groupes de la présente sous-classe
83.
DISPOSABLE DEVICE FOR AUTOMATED BIOLOGICAL SAMPLE PREPARATION
A device and a process for preparing biological test samples are presented. The device has a disposable device with a connection mechanism for connecting to a closed sonication tube together with a filter capture unit to capture samples and to handle the samples without requiring additional tubes. With the device and/or method, samples are sonicated in the closed sonication tube that prevents aerosol contamination.
The issue is to provide a novel polymer, a filler that contains said polymer and is used to measure perfluoro compounds having an acid group at a terminus, a column filled with said filler, and a method that uses said column to measure perfluoro compounds having an acid group at a terminus, as well as a filler that contains the aforementioned polymer and is used to measure medications, a column filled with said filler, and a method for measuring medications using said column. The polymer is obtained by introducing a negative ion substitutent into a glycidyl group of a polymer obtained by polymerizing a compound represented by the general formula [1] and a compound represented by the general formula [2]. The a filler (column) that is used to measure perfluoro compounds having an acid group at a terminus contains said polymer, and the method for measuring perfluoro compounds uses said column. The filler (column) that is used to measure medications contains said polymer, and the method for measuring medications uses said column.
C08F 220/32 - Esters contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle contenant des radicaux époxyde
C08F 220/36 - Esters contenant de l'azote contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle
G01N 1/10 - Dispositifs pour prélever des échantillons à l'état liquide ou fluide
G01N 30/00 - Recherche ou analyse de matériaux par séparation en constituants utilisant l'adsorption, l'absorption ou des phénomènes similaires ou utilisant l'échange d'ions, p. ex. la chromatographie
Disclosed is an oligonucleotide which comprises a part or the whole of a nucleotide sequence depicted in any one of SEQ ID NO:1 to SEQ ID NO:15 or a part or the whole of a nucleotide sequence complementary to a nucleotide sequence depicted in any one of SEQ ID NO:1 to SEQ ID NO:15 and is capable of hybridizing with a nucleotide sequence for a gene of Mycobacterium intracellulare. Also disclosed are a primer and a probe for use in the detection of M. intracellulare, each of which comprises the oligonucleotide. Further disclosed is a method for detecting M. intracellulare by using the primer and/or the probe.
C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
Phenylphosphorylcholine derivatives represented by general formula [1]; a method for calcium ion determination, characterized by mixing a derivative described above with phospholipase D in the presence of phosphomonoesterase to initiate a reaction, measuring the absorbance increase rate, and determining the quantity of calcium ion on the basis of the absorbance increase rate; reagents and kits for calcium ion determination, which contain the derivatives; and reagents for the determination of phospholipase D: [1] wherein R1 to R4 are each independently hydrogen, halogeno, halogenated alkyl, or carboxy, with the proviso that at least one of R1 to R4 is halogeno, halogenated alkyl, or carboxy.
C07F 9/12 - Esters des acides phosphoriques avec des composés hydroxyarylés
C12Q 1/42 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase une phosphatase
C12Q 1/44 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase une estérase
87.
NOVEL PROTEIN CAPABLE OF BINDING TO HYALURONIC ACID, AND METHOD FOR MEASUREMENT OF HYALURONIC ACID USING THE SAME
Disclosed are: a polynucleotide which encodes a protein comprising the amino acid sequence depicted in SEQ ID NO:2, wherein the protein encoded by the polynucleotide is capable of binding to hyaluronic acid; the protein; a method for measuring hyaluronic acid by using the protein; and a reagent kit for measuring hyaluronic acid, which comprises the protein as a constituent component.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p. ex. glutathion
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
88.
AN AQUEOUS SOLUTION FOR APPLYING TO A CHANNEL AND APPLYING METHOD
An aqueous solution containing a buffer and an organosilicone surfactant and a method of applying an aqueous solution containing a buffer and an organosilicone surfactant to a channel are presented. The aqueous solution includes a buffer and an organosilicone surfactant and may also include a blocking agent. The method includes providing an aqueous solution containing a buffer and an organosilicone surfactant, and applying the aqueous solution to the channel having the hydrophobic surfaces. The organosilicone surfactant is used to reduce surface tensions of the solution on the hydrophobic channel. The organosilicone surfactant is combined with the blocking agent for preventing an interaction between the surface of the channel and a component in the aqueous solution.
SEMICONDUCTOR SURFACE TREATING AGENT COMPOSITION AND METHOD FOR TREATING SEMICONDUCTOR SURFACE USING THE SEMICONDUCTOR SURFACE TREATING AGENT COMPOSITION
Disclosed are a semiconductor surface treating agent composition, which can realize easy separation of an antireflection film layer in a production process of a semiconductor element or the like at a low temperature in a short time, and a method for treating a semiconductor surface using the semiconductor surface treating agent composition. The semiconductor surface treating agent composition can realize the separation of both an antireflection film layer and a resist layer and, at the same time, can realize the separation of a resist cured layer produced in an etching process. The semiconductor surface treating agent composition is characterized by comprising a compound, which generates fluorine ions in water, a carbon radical generating agent, and water and optionally an organic solvent. The method for treating a semiconductor surface is characterized by using the composition.
Disclosed are a peptide derivative for assaying β-glucan or an endotoxin which enables a highly sensitive assay and a method of assaying β-glucan and/or an endotoxin using the same. (1) A peptide derivative represented by general formula [1]: X-A1-Gly-Arg-A2-E-D [1]; (2) a reagent for assaying β-glucan and/or an endotoxin which contains the peptide derivative as described above; (3) a method of assaying β-glucan and/or an endotoxin characterized by comprising reacting a sample containing β-glucan and/or the endotoxin with limulus blood cell components and the above-described peptide derivative, separating and quantifying the unreacted substance represented by general formula [2] that has been released consequently: H-A2-E-D [2] and then conducting the assay based on the data; and (4) a reagent kit for assaying β-glucan and/or an endotoxin which contains limulus blood cell components and the above-described peptide derivative as the constituents of the same.
C07K 5/103 - Tétrapeptides la chaîne latérale du premier amino-acide étant acyclique, p. ex. Gly, Ala
C12Q 1/37 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase faisant intervenir une peptidase ou une protéinase
91.
PRIMER AND PROBE FOR DETECTING CHLAMYDOPHILA CAVIAE, AS WELL AS A CHLAMYDOPHILA CAVIAE DETECTION METHOD USING THE SAME
Provided are a novel primer and probe for detecting Chlamydophila caviae, for which diagnostic false positives have been eliminated, as well as a simple, fast and highly precise Chlamydophila caviae detection method using the same. The Chlamydophila caviae detection method that uses the primer and/or probe of this invention can detect Chlamydophila caviae far more rapidly and with greater precision than prior methods that identify microbial species with microbial culture tests, etc. Use of the detection method of this invention also allows quantification of the Chlamydophila caviae itself.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
92.
ETCHING AGENT, ETCHING METHOD AND LIQUID FOR PREPARING ETCHING AGENT
Disclosed is an etching agent for semiconductor substrates, which is capable of etching a titanium-based (Ti-based) metal film or a tungsten-based (W-based) metal film on a semiconductor substrate. The etching agent for semiconductor substrates is composed of a solution containing (A) hydrogen peroxide, (B) a phosphonic acid chelating agent having a hydroxyl group, (C) a basic compound, and (D-1) a copper anticorrosive and/or (D-2) 0.01-3% by weight of two or more anion species other than phosphonic acid chelating agents having a hydroxyl group, which anion species have no oxidizing power.
This invention provides a process for producing a safe and low-cost polycrystalline silicon substrate, which can produce a polycrystalline silicon substrate having excellent photoelectric conversion efficiency and can realize simple formation of an even and fine concave and convex structure suitable for solar cells on a surface of the polycrystalline silicon substrate, and a polycrystalline silicon substrate which has an even and fine pyramid-shaped concave and convex structure and can significantly reduce the reflectance. A polycrystalline silicon substrate is etched with an alkaline etching liquid containing at least one material selected from the group consisting of carboxylic acids having 1 to 12 carbon atoms and containing at least one carboxyl group in one molecule and their salts to form a concave and convex structure on a surface of the polycrystalline silicon substrate.
H01L 21/306 - Traitement chimique ou électrique, p. ex. gravure électrolytique
H01L 31/04 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV]
94.
CARRIER, METHOD AND REAGENT FOR OBTAINING SMALL RNA
Disclosed are: (1) a carrier for obtaining small RNA, which is produced by introducing a polymerizable functional group or a chain-transfer group onto the surface of a core particle, mixing the particle with a polymerizable monomer, allowing the polymerization reaction to proceed to form a layer containing a polymer compound on the surface of the particle, and further immobilizing a physiologically active substance having affinity for a small RNA-binding protein on the surface of the particle; (2) a method for obtaining small RNA, which is characterized by using the carrier; (3) a reagent for obtaining small RNA and/or a nucleic acid that is targeted by small RNA, which comprises the carrier; (4) a reagent kit for obtaining small RNA and/or a nucleic acid that is targeted by small RNA, which comprises the reagent; and (5) a method for obtaining a nucleic acid that is targeted by small RNA, which is characterized by using the carrier.
Disclosed is a novel selective reduction method which can selectively reduce a nitro compound containing an easily reducible group such as a nitrostyrene derivative to an amino compound containing an easily reducible group such as an aminostyrene derivative. The method is a method for selectively reducing a nitro group contained in a nitro aromatic compound containing a reducible group, provided that, when a reducing agent is hydrogen, a metal catalyst-supported carbon is an osmium-supported carbon, a ruthenium-supported carbon, or a platinum-supported carbon. The method is characterized in that a nitro aromatic compound containing a reducible group is reacted with a reducing agent selected from hydrazine or hydrogen in the presence of at least one metal catalyst-supported carbon selected from a platinum-supported carbon, an osmium-supported carbon, a ruthenium-supported carbon, a palladium-supported carbon, and a rhodium-supported carbon.
C07C 209/36 - Préparation de composés contenant des groupes amino liés à un squelette carboné par réduction de liaisons azote-oxygène ou azote-azote par réduction de groupes nitro par réduction de groupes nitro liés à des atomes de carbone de cycles aromatiques à six chaînons
C07C 227/06 - Formation de groupes amino dans des composés contenant des groupes carboxyle par des réactions d'addition ou de substitution, sans augmentation du nombre d'atomes de carbone dans le squelette carboné de l'acide
C07C 229/40 - Composés contenant des groupes amino et carboxyle liés au même squelette carboné ayant des groupes amino liés à des atomes de carbone d'au moins un cycle aromatique à six chaînons et des groupes carboxyle liés à des atomes de carbone acycliques du même squelette carboné
C07C 229/60 - Composés contenant des groupes amino et carboxyle liés au même squelette carboné ayant des groupes amino et carboxyle liés à des atomes de carbone de cycles aromatiques à six chaînons du même squelette carboné avec des groupes amino et carboxyle liés à des atomes de carbone du même cycle aromatique à six chaînons non condensé avec des groupes amino et carboxyle liés en positions méta ou para
Disclosed are: a simple and safe method for synthesizing single- or double-stranded DNA; and a kit for use in the synthesis. Specifically disclosed are: (1) a method for synthesizing single-stranded DNA comprising a nucleotide sequence corresponding to template RNA, which is characterized by comprising the following steps: 1) step 1 - subjecting template RNA to a reverse transcription reaction; and 2) step 2 - subjecting a solution obtained by the treatment in the step 1 to the treatment with an alkali; (2) a method for synthesizing double-stranded DNA comprising a nucleotide sequence corresponding to template RNA, which is characterized by comprising the following steps: 1) step 1 - subjecting template RNA to a reverse transcription reaction; 2) step 2 - subjecting a solution obtained by the treatment in step 1 to the treatment with an alkali; and 3) step 3 - producing double-stranded DNA from the single-stranded DNA produced in the step 2; (3) a kit for use in the synthesis of single-stranded DNA, which can be used in the above-mentioned synthesis method; and (4) a kit for the synthesis of double-stranded DNA, which can be used in the above-mentioned synthesis method.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
Provided is a reagent container, which requires no strength for a probe and which can reduce the contamination of the probe or the like, thereby to detect the liquid level precisely at all times and to open the container easily. The reagent container (50) has a plurality of opened reagent containing portions (52a, 52b, 52c and 52d), from which a reagent is sucked by inserting a probe thereinto. The open portions (66) of all the containing portions (52a, 52b, 52c and 52d) are sealed with at least one sheet of seal member (62). The reagent container (50) includes a container body (52), and a cover member (54) having its lower face formed to have a plurality of hollow bored portions (64) boring the seal members (62) in the individual open portions (66) and protruding downward, and its upper face formed to have openings (86) for making the insertion and extraction of the probes possible to communicate with the bored portions (64).
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
98.
NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, SPACER AND LIQUID CRYSTAL DISPLAY
Disclosed is a negative photosensitive resin composition suitable as a photosensitive material for spacers. Specifically disclosed is a negative photosensitive resin composition having excellent developability, which enables to produce a spacer having high shrinkage ratio and high elasticity recovery ratio. Also disclosed are a spacer produced by using such a negative photosensitive resin composition, and a liquid crystal display. The negative photosensitive resin composition is characterized by containing [A] an alkali-soluble resin (a) composed of a monomer unit derived from an unsaturated carboxylic acid and a monomer unit derived from a radically polymerizable unsaturated compound, and an alkali-soluble resin (b) composed of a monomer unit derived from an unsaturated carboxylic acid and a monomer unit derived from an epoxy group-containing radically polymerizable unsaturated compound, [B] a polyfunctional (meth)acrylate and [C] a photopolymerization initiator. Also specifically disclosed are a spacer made of such a negative photosensitive resin composition, and a liquid crystal display comprising such a spacer.
A process for producing a high-purity hydroxytriphenylene compound in which not only inexpensive raw materials can be used but no complicated steps such as protective-group elimination, e.g., dealkylation, and reduction are necessary. It is advantageous in industrial production. Also provided is a novel crystal of 2,3,6,7,10,11-hexahydroxytriphenylene monohydrate which has satisfactory thermal stability. The process, which is for producing a compound represented by the general formula (2), is characterized by reacting a compound represented by the general formula (1) in the presence of a metal oxide containing a metal selected among trivalent iron, pentavalent vanadium, and hexavalent molybdenum and of a nonvolatile strong acid. (In the formula (1), the two R's each independently represents hydrogen, halogeno, C1-3 alkyl, or C1-3 alkoxy.)
C07C 37/11 - Préparation de composés comportant des groupes hydroxyle ou O-métal liés à un atome de carbone d'un cycle aromatique à six chaînons par des réactions augmentant le nombre d'atomes de carbone
C07C 37/84 - SéparationPurificationStabilisationEmploi d'additifs par traitement physique par cristallisation
C07C 39/12 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques sans autre insaturation que celle des cycles aromatiques
[PROBLEMS] To provide a method of efficiently deuterating a substrate with the use of a ruthenium catalyst. [MEANS FOR SOLVING PROBLEMS] The method of deuteration is characterized in that a compound having hydroxyl, an optionally substituted amino, an ether bond and/or -NH- is reacted with a deuterium source in the copresence of a ruthenium catalyst and hydrogen gas.
C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
C07C 29/00 - Préparation de composés comportant des groupes hydroxyle ou O-métal liés à un atome de carbone ne faisant pas partie d'un cycle aromatique à six chaînons
C07C 41/18 - Préparation d'éthers par des réactions ne formant pas de liaisons sur l'oxygène de la fonction éther
C07C 209/68 - Préparation de composés contenant des groupes amino liés à un squelette carboné à partir d'amines, par des réactions n'impliquant pas de groupes amino, p. ex. réduction d'amines non saturées, aromatisation ou substitution du squelette carboné
C07C 227/16 - Préparation de composés contenant des groupes amino et carboxyle liés au même squelette carboné à partir de composés contenant déjà des groupes amino et carboxyle ou leurs dérivés par des réactions n'impliquant pas les groupes amino ou carboxyle
C07D 295/02 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de carbone du cycle contenant uniquement des atomes d'hydrogène et de carbone en plus des hétéro-éléments du cycle
B01J 23/46 - Ruthénium, rhodium, osmium ou iridium
brevets
