DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Ahn, Sangmee
Koh, Jin-Sung
Choi, Yongseok
Abrégé
The present invention provides a novel thiophene derivative, an optical isomer thereof, or a pharmaceutically acceptable salt thereof. A novel thiophene derivative according to the present invention has excellent inhibitory activity against KDM4, and thus is useful as a therapeutic agent for brain diseases such as Alzheimer's disease.
C07D 333/38 - Atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
A61K 31/381 - Composés hétérocycliques ayant le soufre comme hétéro-atome d'un cycle ayant des cycles à cinq chaînons
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
C07D 409/10 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
2.
CELL CULTURE PLATFORM CAPABLE OF SIMULATING MICROGRAVITY, AND CELL CULTURE COMPRISING CELLS PREPARED THEREFROM
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Oh, Se Heang
Kim, Ho Yong
Abrégé
The present invention relates to: a cell culture platform in which cell culture is enabled in a state capable of simulating microgravity by mixing a density control solution into a cell culture medium to adjust density of the cell culture medium to a density range of cells; and a cell culture comprising cells prepared therefrom. Since the cell culture platform of the present invention can overcome limitations of existing microgravity platforms simulated on the ground, including excessive cost and side effects caused by application of additional external force, the cell culture platform is expected to be usefully applicable in the aspects of regenerative medicine, immunology, and pharmacology as well as in those of space biology and space medicine.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
3.
PHARMACEUTICAL COMPOSITION CONTAINING ODC1 INHIBITOR AS ACTIVE INGREDIENT FOR INHIBITING ANTICANCER DRUG TOLERANCE, RECOVERING ANTICANCER DRUG RESPONSIVENESS, OR ENHANCING ANTICANCER DRUG SENSITIVITY
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Cho, Jeong Hee
Kim, Su Jin
Abrégé
The present invention relates to a pharmaceutical composition for inhibiting anticancer drug tolerance, recovering anticancer drug responsiveness, or enhancing anticancer drug sensitivity, the composition containing an ODC1 inhibitor as an active ingredient. More specifically, it was found that if ODC1 expression or activity is inhibited when inducing EGFR-targeting drug tolerance using a non-small cell lung cancer cell model overexpressing a kinase involved in EGFR-targeting drug tolerance induction and an animal model xenografted with same, the acquisition of EGFR-targeting drug tolerance caused by kinase overexpression is inhibited and the tolerance is alleviated, and thus drug responsiveness is recovered. Therefore, an agent that inhibits the ODC1 expression or activity can be effectively used as an effective ingredient in a pharmaceutical composition for inhibiting anticancer drug tolerance, recovering anticancer drug responsiveness, or enhancing anticancer drug sensitivity.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
4.
NANOCOMPOSITE SOLDER CONTAINING TWO-DIMENSIONAL NANOMATERIAL AND SOLDERING METHOD FOR NANOCOMPOSITE SOLDER USING REFLOW OPERATION
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Son, Yoon Chul
Park, Young Ju
Woo, Yun Sung
Lee, Jae Jeong
Xue, Han
Kim, Bo Hyeon
Abrégé
One embodiment of the present invention provides a nanocomposite solder containing a two-dimensional nanomaterial and a soldering method for the nanocomposite solder using a reflow operation. The nanocomposite solder according to an embodiment of the present invention confines the two-dimensional nanomaterial in a tin-containing paste, thereby reducing the grain size of the solder and enhancing hardness. As a result, the nanocomposite solder has enhanced mechanical properties and thermal conductivity, thereby exhibiting enhanced heat dissipation characteristics.
B23K 35/26 - Emploi de matériaux spécifiés pour le soudage ou le brasage dont le principal constituant fond à moins de 400°C
B23K 35/02 - Baguettes, électrodes, matériaux ou environnements utilisés pour le brasage, le soudage ou le découpage caractérisés par des propriétés mécaniques, p. ex. par la forme
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Choi, Bong Geun
Do, Eun Jae
Mun, Seyoung
Park, So Hyeon
Choi, Su Been
Han, Kyudong
Abrégé
The present invention relates to a pharmaceutical composition for preventing or treating neurological diseases, comprising dextromethorphan as an active ingredient. When the compound is applied to damaged nerve cells, it was confirmed that nerve regeneration effects such as increased cell viability of the nerve cells and increased average neurite length and maximum neurite length are exhibited, and thus the composition can be effectively utilized as a composition for preventing, treating, or alleviating neurological diseases.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Eom, Joobeom
Kim, Kanghae
Park, Yourim
Abrégé
The present invention relates to a ceiling-type patient bio-signal monitoring system and a patient bio-signal monitoring method using same, wherein the ceiling-type patient bio-signal monitoring system functions as a CCTV and, when it is necessary to measure bio-signals of a patient, identifies the patient through real-time face tracking of the patient, measures an optical signal of the patient in a non-contact manner, and measures bio-signals such as heart rate, respiration, and oxygen saturation through image analysis. To this end, the present invention provides a ceiling-type patient bio-signal monitoring system characterized by comprising: a sensor unit for irradiating a patient with light; an analysis unit for analyzing images and bio-signals of the patient on the basis of reflected light that is light emitted from the sensor unit and reflected by the patient; and a bio-signal output unit for outputting the bio-signals of the patient analyzed by the analysis unit, wherein the bio-signals include the heart rate, respiration, and oxygen saturation of the patient.
A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
7.
STRONTIUM-EMITTING 3D PRINTING SCAFFOLD FOR PROMOTING BONE CARTILAGE REGENERATION AND METHOD FOR MANUFACTURING SAME
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Hae-Won
Kim, Hye Sung
Li, Chengji
Lee, Jung-Hwan
Park, Jeong-Hui
Abrégé
The present invention relates to a strontium-emitting 3D printing scaffold for promoting bone cartilage regeneration and a method for manufacturing same. The scaffold continuously maintains the emission of a triad of ions including strontium (Sr), silicate (Si), and calcium (Ca) to promote cell migration to a damaged site, and has a hierarchical porous structure, and thus enhances tissue regeneration by increasing cell engraftment, immune regulation, and angiogenesis, and exhibits an excellent anti-inflammatory effect. Therefore, the scaffold can be effectively used for the regeneration of damaged bone and cartilage tissue.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kang, Dong Hye
Abrégé
The present invention relates to a fracture restoration and support device and, more specifically, provides a fracture restoration and support device, using a tube unit and a balloon, to be installed in the maxillary sinus below a fractured orbital floor and support the orbital floor and maxillary anterior wall that are surgically repositioned.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Eom, Joobeom
Kim, Kanghae
Park, Yourim
Abrégé
The present invention relates to a non-contact type burn diagnosis device and method using an imaging device and, more specifically, to a non-contact type burn diagnosis device and method using an imaging device, wherein the imaging device includes a light irradiation unit, an image acquisition unit, and a diagnosis information calculation unit and can assess the extent of internal skin damage and evaluate the severity of burns by analyzing blood flow information distinguished by wavelength bands and thus enables non-invasive and non-contact diagnosis of burn-induced skin damage.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Eun Jung
Jang, Jun Hwee
Han, Cheol Min
Abrégé
The present invention relates to a natural light crosslinked hydrogel comprising MXene and a method for preparing same. The present invention provides a natural polymeric hydrogel formed through natural light crosslinking in a non-harmful visible light spectrum. As the hydrogel comprises a drug and MXene, the hydrogel exhibits excellent biocompatibility with no cytotoxicity. It has been confirmed that the hydrogel can maximize a wound healing effect by modulating photothermal reactions and controlling drug release. Accordingly, the hydrogel may be effectively used for wound treatment as a pharmaceutical composition, a quasi-drug composition, and a cosmetic composition.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Kyoung Min
Abrégé
The present disclosure relates to an apparatus and a method for providing bilateral stimulation, the apparatus comprising: a communication module for performing communication with an external device; a storage module for storing at least one process for providing vibration-based stimulation to the skin of a user; a vibration module for generating vibration by using at least one vibrator on the basis of a vibration pattern; and a control module for performing an operation for providing vibration-based stimulation to the skin of the user on the basis of the at least one process, wherein the control module can: provide, when request information is input by the user, mode information configured to select at least one from among a plurality of modes on the basis of the request information; configure, when the at least one mode from among the plurality of modes is selected, the vibration pattern on the basis of selection information about the selected at least one mode; and provide vibration stimulation according to the configured vibration pattern.
A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 20/70 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mentales, p. ex. la thérapie psychologique ou le training autogène
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
12.
APPARATUS AND METHOD FOR SKIN VIBRATION STIMULATION
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Kyoung Min
Abrégé
The present disclosure relates to an apparatus and a method for providing skin vibration stimulation, the apparatus for providing skin vibration stimulation comprising: a communication module that performs communication with an external device; a storage module for storing at least one process for providing vibration-based stimulation to the skin of a user; a vibration module for generating vibration by using at least one vibrator on the basis of a vibration pattern; and a control module that performs an operation for providing vibration-based stimulation to the skin of the user on the basis of the at least one process, wherein the control module, when request information is input from the user, provides mode information configured to allow selection of at least one of a plurality of modes on the basis of the request information, and when at least one mode among the plurality of modes is selected, configures the vibration pattern on the basis of selection information for the selected at least one mode, and provides vibration stimulation according to the configured vibration pattern.
A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p. ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
G16H 40/60 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
13.
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ATTENTION DEFICIT/HYPERACTIVITY DISORDER, CONTAINING KDS2010 AS ACTIVE INGREDIENT
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Yoon, Bo-Eun
Park, Ki Duk
Park, Jong-Hyun
Abrégé
The present invention relates to a pharmaceutical composition for preventing or treating attention deficit/hyperactivity disorder (ADHD), containing KDS2010 as an active ingredient, wherein it has been identified, in a Git1 gene-deficient hetero (+/−) mouse, that the amount of GABA is increased in the striatum of the brain, which is in charge of hyperactivity, and thus the mouse can be used as an animal model of ADHD, and it has been identified that inattention and hyperactivity are alleviated upon the administration of KDS2010 to the Git1 gene-deficient hetero (+/−) mouse, and thus KDS2010 is provided as an agent for treating ADHD.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Ji-Young
Heo, Pil-Won
Nasir, Mohammad
Park, Hee-Jung
Abrégé
The present invention provides a ceramic sheet, a method for preparing same, and an all-solid secondary battery comprising same. According to the present invention, provided is a garnet-type oxide-based ceramic sheet that contains a garnet-type oxide and comprises a surface layer and a deep layer, wherein the average lithium content in garnet-type oxide particles in the surface layer is greater than the average lithium content in garnet-type oxide particles in the deep layer, and the ratio of the average lithium content in the garnet-type oxide in the surface layer to the average lithium content in the garnet-type oxide in the deep layer is greater than 1 and less than 1.014.
C04B 35/48 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxydes de zirconium ou d'hafnium ou de zirconates ou d'hafnates
METHOD FOR MANUFACTURING METAL COMPOSITE THROUGH LIQUID METAL DEALLOYING USING MOLTEN MG-CA ALLOY AND TI-BASED PRECURSOR ALLOY, AND METAL COMPOSITE MANUFACTURED THEREBY
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Sung Hyuk
Jang, Jee Eun
Lee, Seung Ho
Joo, Soo Hyun
Abrégé
The present invention relates to a method for manufacturing a Mg/Ti composite, and a metal composite manufactured thereby, the method immersing, in a molten metal that contains (Mg) and calcium (Ca), a precursor alloy (Ti-X) that contains titanium (Ti) and a metal (X), which is miscible with the molten metal so as to be dissolved into the molten metal, wherein the Ca alloy element, which is included in a molten Mg-Ca alloy, is highly miscible with Cu so as to promote dealloying behavior by which Cu is dissolved into the molten metal, thereby greatly reducing process time, is dissolved in Mg matrix so as to increase the volume fraction of the Mg matrix in the composite, and reduces the coarsening rate of Ti and, simultaneously, improves the strength of the composite through solid-solution strengthening of the Mg matrix.
METHOD FOR MANUFACTURING MG/TIAL COMPOSITE WITH THREE-DIMENSIONAL INTERCONNECTED STRUCTURE BY USING LIQUID METAL DEALLOYING, AND MG/TIAL COMPOSITE MANUFACTURED THEREBY
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Sung Hyuk
Jang, Jee Eun
Joo, Soo Hyun
Abrégé
The present invention relates to a method for manufacturing a Mg/TiAl composite, and a Mg/TiAl composite manufactured thereby, the method comprising the steps of: (a) immersing, in a molten metal containing magnesium (Mg), a precursor alloy (Ti-X) containing a metal (X), which is miscible with titanium (Ti) and is to be dissolved in the molten metal, thereby manufacturing a Mg/Ti composite; (b) manufacturing a titanium (Ti) porous structure from the Mg/Ti composite; and (c) immersing the titanium (Ti) porous structure in a molten Mg-Al alloy, thereby manufacturing a Mg/TiAl composite. A magnesium matrix material is removed from a Mg-Ti composite manufactured through liquid metal dealloying (LMD), and then aluminum alloying is performed using the molten Mg-Al alloy, and thus a Mg/TiAl composite structured to be a three-dimensionally interconnected, in which an element such as copper (Cu) contained in the precursor alloy does not remain and which has excellent physical properties, can be manufactured.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
INSTITUTE FOR BASIC SCIENCE (République de Corée)
Inventeur(s)
Yoon, Bo-Eun
Lee, C. Justin
Kim, Yoo Sung
Sa, Moonsun
Abrégé
The present invention relates to a pharmaceutical composition for preventing or treating attention deficit/hyperactivity disorder (ADHD), including SNAP5114 as an active ingredient. A Git1 gene-deficient hetero (+/−) mouse, confirmed to have increased amount of GABA in the brain striatum that controls hyperactivity, can be used as an animal model of ADHD, and by confirming that hyperactivity is ameliorated by administering SNAP5114 to the Git1 gene-deficient hetero (+/−) mouse, SNAP5114 is provided as a therapeutic agent for ADHD.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
18.
LITHIUM LANTHANUM ZIRCONIUM OXIDE-BASED CERAMIC, METHOD FOR PRODUCING SAME, AND ALL-SOLID-STATE LITHIUM SECONDARY BATTERY INCLUDING SAME
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Ji-Young
Heo, Pil-Won
Nasir, Mohammad
Park, Hee-Jung
Abrégé
A method for producing a lithium lanthanum zirconium oxide (LLZO)-based ceramic according to an embodiment of the present invention comprises a sintering step for sintering an oxide sheet that contains an LLZO powder containing the elements lithium, lanthanum, and zirconium. The sintering step may include a first sintering step for sintering at a temperature of T1 and a second sintering step for sintering at a temperature of T2 lower than T1. An LLZO-based ceramic according to another embodiment of the present invention has a relative density of at least 88% and is composed of grains having a size of 1-10 µm, wherein the standard deviation of the grain size is 80% or less of the average grain size, and the grains may have a cubic crystal structure.
C04B 35/48 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxydes de zirconium ou d'hafnium ou de zirconates ou d'hafnates
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Ahn, Ju Hee
Abrégé
The present invention relates to a method for recovering an ionomer or catalyst from a used or defective membrane electrode assembly or ion exchange membrane, the method comprising the steps of: subjecting the membrane electrode assembly or ion exchange membrane to supercritical dispersion in a mixed solvent of alcohol and water to extract the ionomer, filtering and separating the extracted ionomer dispersion liquid; and filtering and separating the catalyst from the remaining components after the separation of the ionomer dispersion liquid.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Yoo, Shin Hyuk
Lee, Jun Hee
Mo, Ji Hun
Kim, Hae Won
Bae, Jun Sang
Yun, Yeo Gyun
Abrégé
The present invention relates to a composition comprising, as an active ingredient, a three-dimensional human exfoliated deciduous teeth stem cell spheroid prepared by introducing a low-rigidity three-dimensional spheroid preparation method. The composition can address the issue of deterioration of a cell function due to ultra-high rigidity caused by culturing conventional stem cells in a two-dimensional cell incubator, and efficiently improve the recovery of olfactory endothelial thickness, the regeneration of olfactory cilia, the regeneration of olfactory nerves, and the olfactory sensing function for a subject with anosmia, and thus can be utilized in the prevention or treatment of anosmia.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Cho, Jeong Hee
Kim, Su Jin
Cho, Da Seul
Abrégé
The present invention relates to a pharmaceutical composition for treating cancer resistant to EGFR targeted therapy. It has been confirmed that PRMT5 activity plays a crucial role when resistance to EGFR targeted therapy is acquired due to kinase overexpression involved in the induction of resistance to the therapy in cancer, as well as when re-resistance to the therapy is acquired after a drug holiday of EGFR targeted therapy due to kinase overexpression involved in re-resistance induction. In addition, by inhibiting PRMT5 expression or activity, the biological pathway induced by the kinase overexpression that leads to EGFR targeted therapy resistance or re-resistance can be blocked whereby the acquirement of EGFR targeted therapy resistance and re-resistance post-drug holiday due to the kinase overexpression is suppressed, resulting in alleviating resistance and restoring drug responsiveness. Therefore, PRMT5 inhibitors can be effectively used as active ingredients in pharmaceutical compositions aimed at inhibiting resistance to EGFR targeted anticancer drugs, preventing re-resistance post-EGFR targeted therapy drug holiday, restoring anticancer drug responsiveness, or enhancing sensitivity to the anticancer agent.
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p. ex. clozapine, dilazèpe
A61K 31/517 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. quinazoline, périmidine
A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
A61K 31/444 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. amrinone
22.
Method for manufacturing membrane-electrode assembly using nano-dispersed ionomer binder, and membrane-electrode assembly manufactured thereby
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Lim, Jun Hyun
Abrégé
The present invention relates to a method for manufacturing a membrane-electrode assembly and a membrane-electrode assembly manufactured thereby, and more specifically, to a method for manufacturing a membrane-electrode assembly by using a nano-dispersed ionomer binder under supercritical conditions in a mixed solvent comprising alcohol and water, and a membrane-electrode assembly manufactured thereby and a fuel cell or water electrolysis device comprising same.
H01M 8/1004 - Éléments à combustible avec électrolytes solides caractérisés par les ensembles membrane-électrodes [MEA]
C25B 9/23 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes comprenant des membranes échangeuses d'ions dans ou sur lesquelles est incrusté du matériau pour électrode
H01M 8/10 - Éléments à combustible avec électrolytes solides
23.
CHEMICALLY-INDUCED OSTEOGENIC CELLS AND USE THEREOF IN DISEASE MODELING, AND SCAFFOLD FOR BONE GRAFTING
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Hae Won
Lee, Jung Hwan
Yoon, Ji Young
Abrégé
The present invention provides a medium composition for direct differentiation of osteogenic cells and a method for direct differentiation of osteogenic cells, which induce osteogenic cells from somatic cells, the composition comprising, as active ingredients, chemicals, that is, a TGF-β receptor inhibitor (RepSox), a cAMP signaling activator (Forskolin) and an epithelial Na+ channel inhibitor (Phenamil). It has been identified that a composition comprising osteogenic cells prepared through the method is effective in treating or preventing osteogenesis imperfecta, which is a prototypical bone disease, and Proteus syndrome, and thus can be effectively used as a composition for preventing or treating bone diseases.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Kwangmi
Han, Young Taek
Abrégé
The present invention relates to a pharmaceutical composition for preventing or treating inflammatory skin diseases, the composition containing sibiriaester B as an active ingredient. Sibiriaester B was found to not exhibit cytotoxicity and to exhibit the effects of promoting interleukin 2 (IL-2) production and suppressing interleukin 13 (IL-13) production in mouse T cells, and thus can be effectively used as a composition for preventing, treating or ameliorating inflammatory skin diseases.
A61K 31/216 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides ayant des cycles aromatiques, p. ex. bénactizyne, clofibrate
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Choi, Bong Geun
Sim, Da Woon
Abrégé
The present invention relates to a triazolo thiadiazine-based compound, and a composition for preventing or treating sarcopenia, the composition containing the triazolo thiadiazine-based compound as an active ingredient. The triazolo thiadiazine-based compound was found to exhibit the effect of ameliorating the atrophy of myotubes formed from myoblast, and thus the composition containing the triazolo thiadiazine-based compound as an active ingredient can be effectively used as a composition for preventing, treating, or ameliorating sarcopenia.
A61K 31/549 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. sulthiame ayant plusieurs atomes d'azote dans le même cycle, p. ex. hydrochlorothiazide
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
26.
FURYLTHIAZOLE-BASED COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING SARCOPENIA COMPRISING SAME AS ACTIVE INGREDIENT
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Choi, Bong Geun
Sim, Da Woon
Abrégé
The present invention relates to a composition for preventing or treating sarcopenia, comprising a furylthiazole-based compound represented by chemical formula 1 as an active ingredient, and the furylthiazole-based compound has been confirmed to exhibit the effect of ameliorating atrophy of root canals formed in myoblasts, and thus can be useful as a composition for preventing, treating, or ameliorating sarcopenia.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, So-Young
Lee, Chung Hyun
Hwang, Kwang Woo
Abrégé
Provided is a composition for preventing, alleviating or treating neurodegenerative disorders, comprising, as an active ingredient, a Davallia mariesii extract or a fraction thereof, or a compound isolated therefrom.
A61K 36/11 - Pteridophyta ou filicophyta (fougères)
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A23L 33/125 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sirops d'hydrate de carboneModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sucresModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des alcools de sucreModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des hydrolysats d'amidon
A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Hwang, Jin Pyo
Abrégé
The present inventive concept relates to a chemically modified anion exchange membrane and a method of preparing the same and, more particularly, an anion exchange membrane in which sulfonic acid groups in a perfluorinated sulfonic acid electrolyte membrane are substituted with anion conductive groups such as an ammonium group, a phosphonium group, an imidazolium group, a pyridinium group and a sulfonium group, and a method of preparing an anion exchange membrane by chemically modifying sulfonic acid groups in a perfluorinated sulfonic acid electrolyte membrane.
B01D 71/64 - PolyimidesPolyamide-imidesPolyester-imidesPolyamide-acides ou précurseurs similaires de polyimides
B01D 71/66 - Polymères contenant, dans la chaîne principale, uniquement du soufre, avec ou sans azote, oxygène ou carbone
B01J 39/20 - Composés macromoléculaires obtenus par des réactions ne faisant intervenir que des liaisons carbone-carbone non saturées
B01J 41/13 - Composés macromoléculaires obtenus autrement que par des réactions ne faisant intervenir que des liaisons carbone-carbone non saturées
B01J 41/14 - Composés macromoléculaires obtenus par des réactions ne faisant intervenir que des liaisons carbone-carbone non saturées
29.
METHOD FOR PREPARING HIGHLY-DISPERSIBLE RADICAL SCAVENGER METAL OXIDE-IONOMER NANOCOMPOSITE BY USING SELF-ASSEMBLY PROCESS AND FUEL CELL COMPRISING NANOCOMPOSITE PREPARED THEREBY
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Abrégé
The present invention relates to: a method for preparing a nanocomposite of an ionomer and a metal oxide acting as a radical scavenger; and a fuel cell comprising a nanocomposite prepared thereby and, more specifically, to: a method for preparing a highly-dispersible radical scavenger metal oxide-ionomer nanocomposite which can be redispersed to the size of nanoparticles in an aqueous alcohol solution or an ionomer solution; and a membrane electrode assembly and fuel cell comprising a nanocomposite prepared thereby.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Woo, Seung Hoon
Abueva, Celine
Bae, Jun Sang
Ryu, Hyun Seok
Chung, Pil Sang
Eom, Joo Beom
Park, So Young
Abrégé
The present invention relates to a physiological saline which includes N,N,N-trimethyl chitosan, thus having the advantages of an excellent anti-adhesion effect as well as an excellent antibacterial or hemostatic effect.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Ahn, Ju Hee
Abrégé
The present invention relates to a method for recovering an ionomer or catalyst from a used or defective membrane electrode assembly or ion exchange membrane, the method comprising the steps of: subjecting the membrane electrode assembly or ion exchange membrane to supercritical dispersion in a mixed solvent of alcohol and water to extract the ionomer; filtering and separating the extracted ionomer dispersion liquid; and filtering and separating the catalyst from the remaining components after the separation of the ionomer dispersion liquid.
B01J 8/00 - Procédés chimiques ou physiques en général, conduits en présence de fluides et de particules solidesAppareillage pour de tels procédés
H01M 8/1069 - Matériaux d’électrolyte polymère caractérisés par le procédé de fabrication
C08J 3/09 - Production de solutions, dispersions, latex ou gel par d'autres procédés que ceux utilisant les techniques de polymérisation en solution, en émulsion ou en suspension dans des liquides organiques
H01M 8/10 - Éléments à combustible avec électrolytes solides
32.
FORMULATION FOR ORAL ADMINISTRATION CONTAINING CELECOXIB, USING SELF-NANOEMULSIFIED DRUG DELIVERY SYSTEM, AND PREPARATION METHOD THEREFOR
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Jin, Sung Giu
Choi, Han Gon
Kim, Jong Oh
Kim, Jung Suk
Woo, Mi Ran
Cheon, Seung Hyun
Abrégé
The present invention relates to a formulation for oral administration containing celecoxib and a preparation method therefor, the formulation comprising: a self-nanoemulsified liquid base composition containing celecoxib, oil, a surfactant, and a co-surfactant; and a solid carrier, wherein the solid carrier is a compound containing silicon. The formulation has the effect of significantly increasing the water solubility of celecoxib, and in addition, can increase the dissolution amount and oral bioavailability.
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/22 - Composés hétérocycliques, p. ex. acide ascorbique, tocophérol ou pyrrolidones
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
33.
COMPOSITION COMPRISING REBOXETINE AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF SARCOPENIA
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Bae, Sang Hoon
Abrégé
The present invention relates to a composition comprising reboxetine as an active ingredient for prevention or treatment of sarcopenia. In the present invention, reboxetine is identified to have an effect of alleviating the atrophy of myotubes formed in myoblasts and as such, is provided as a novel medication for prevention, treatment, or alleviation of sarcopenia.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Hee Jung
Lee, Sang Eun
Abrégé
Provided is a metal-supported solid oxide fuel cell comprising a contact layer. Provided is a metal-supported solid oxide fuel cell comprising a contact layer, the solid oxide fuel cell comprising a metal support, and a contact layer, an anode layer, an electrolyte layer, and a cathode layer which are sequentially laminated on the upper portion of the metal support, wherein the contact layer is inserted in a cell of the fuel cell so as to reduce a difference in microstructure between the layers, and a gradient is applied in terms of microstructure so as to increase lifespan and improve heat cycle properties.
H01M 8/1213 - Éléments à combustible avec électrolytes solides fonctionnant à haute température, p. ex. avec un électrolyte en ZrO2 stabilisé caractérisés par la combinaison électrode/électrolyte ou par le matériau de support
H01M 4/86 - Électrodes inertes ayant une activité catalytique, p. ex. pour piles à combustible
H01M 4/90 - Emploi de matériau catalytique spécifié
H01M 8/1246 - Éléments à combustible avec électrolytes solides fonctionnant à haute température, p. ex. avec un électrolyte en ZrO2 stabilisé caractérisés par le procédé de fabrication ou par le matériau de l’électrolyte l'électrolyte étant constitué d’oxydes
H01M 8/124 - Éléments à combustible avec électrolytes solides fonctionnant à haute température, p. ex. avec un électrolyte en ZrO2 stabilisé caractérisés par le procédé de fabrication ou par le matériau de l’électrolyte
35.
CURRENT COLLECTOR COMPRISING PRECIOUS METAL PASTE AND 2D METAL OXIDE, SOLID OXIDE FUEL CELL USING SAME, AND MANUFACTURING METHOD THEREFOR
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Hee Jung
Lee, Sang Eun
Abrégé
Provided are a solid oxide fuel cell to which a current collector comprising a precious metal paste and a 2D metal oxide is applied, and a manufacturing method therefor. The current collector in which a 2D metal oxide is added to a precious metal paste is adapted to make gas flow smoothly therein. In addition, a microstructural gradient is imparted to the current collector, thereby providing a solid oxide fuel cell having a prolonged lifespan and an improved thermal cycle characteristic.
H01M 8/1213 - Éléments à combustible avec électrolytes solides fonctionnant à haute température, p. ex. avec un électrolyte en ZrO2 stabilisé caractérisés par la combinaison électrode/électrolyte ou par le matériau de support
H01M 4/86 - Électrodes inertes ayant une activité catalytique, p. ex. pour piles à combustible
H01M 4/90 - Emploi de matériau catalytique spécifié
H01M 8/1246 - Éléments à combustible avec électrolytes solides fonctionnant à haute température, p. ex. avec un électrolyte en ZrO2 stabilisé caractérisés par le procédé de fabrication ou par le matériau de l’électrolyte l'électrolyte étant constitué d’oxydes
H01M 8/124 - Éléments à combustible avec électrolytes solides fonctionnant à haute température, p. ex. avec un électrolyte en ZrO2 stabilisé caractérisés par le procédé de fabrication ou par le matériau de l’électrolyte
36.
METHOD AND SYSTEM FOR EVALUATING NEUROPROTECTIVE EFFECT OF THERAPEUTIC AGENT ON ASTROCYTE RESILIENCE IN ALZHEIMER'S ANIMAL DISEASE MODEL
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Son, Hye Joo
Abrégé
The present invention relates to a method for evaluating a neuroprotective effect of a therapeutic agent on astrocyte resilience in an Alzheimer animal model. The method for evaluating a neuroprotective effect of a therapeutic agent may comprise the steps of: 1) measuring a cognitive resilience index through a cognitive behavior experiment in the Alzheimer animal model to which the therapeutic has been administered, 2) analyzing the distribution of brain cells through three-dimensional fluorescent microscopic images in the brain tissue of the animal model that has undergone tissue clearing pretreatment, and 3) analyzing the distribution of brain cells through confocal microscopic images in the brain tissue of the animal model that has undergone tissue clearing pretreatment.
G16B 15/00 - TIC spécialement adaptées à l’analyse de structures moléculaires bidimensionnelles ou tridimensionnelles, p. ex. relations structurelles ou fonctionnelles ou alignement de structures
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
37.
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ATTENTION DEFICIT/HYPERACTIVITY DISORDER, CONTAINING KDS2010 AS ACTIVE INGREDIENT
A61K 31/445 - Pipéridines non condensées, p. ex. pipérocaïne
A61P 25/18 - Antipsychotiques, c.-à-d. neuroleptiquesMédicaments pour le traitement de la manie ou de la schizophrénie
A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
39.
ULTRATHIN AND TRANSPARENT CONDUCTIVE ELECTRODE, AND MANUFACTURING METHOD THEREFOR
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Hee Jung
Oh, Jae Myoung
Abrégé
The present invention relates to a transparent electrode made of a novel material, and a manufacturing method therefor. Specifically, the present invention manufactures a nanosheet comprising a metal-based material by applying reduction using, as a starting phase, a transition metal oxide having a two-dimensional layered structure.
H01B 5/14 - Conducteurs ou corps conducteurs non isolés caractérisés par la forme comprenant des couches ou pellicules conductrices sur supports isolants
H01B 1/22 - Matériau conducteur dispersé dans un matériau organique non conducteur le matériau conducteur comportant des métaux ou des alliages
H01B 13/00 - Appareils ou procédés spécialement adaptés à la fabrication de conducteurs ou câbles
40.
PROBIOTIC MOMORDICA CHARANTIA FERMENTATE WITH ENHANCED ANTI-DIABETIC, ANTI-DEMENTIA, AND ANTI-OXIDATIVE FUNCTION
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Misook
Jeong, Yoonhwa
Ryu, Jaesik
Seong, Hui-Yeong
Oh, Su Jin
Yoon, Jiwon
Jang, Hyunah
Choi, Jin A
Abrégé
The present invention relates to a probiotic Momordica charantia fermentate with enhanced anti-diabetic, anti-dementia, and anti-oxidative functions and a preparation method therefor and, more specifically, provides a method for preparing a Momordica charantia fermentate having enhanced anti-dementia activity and a Momordica charantia fermentate prepared according thereto, wherein the method comprises the steps of: adding a sugar ingredient to prepare a Momordica charantia fermentate with a sugar content of 3 to 15 degrees Brix; and fermenting the prepared mixture by inoculating a probiotic strain thereinto. With enhanced anti-dementia, anti-diabetic, and anti-oxidative activities, the Momordica charantia fermentate can be applied to a pharmaceutical composition and a health functional food composition for prevention, treatment, or alleviation of cognitive impairment or diabetes mellitus.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Jeong, Hyung Mo
Park, Hee Jung
Abrégé
The present application relates to a lithium metal battery comprising: a lithium metal anode; a separator positioned on the anode; and a cathode formed on the separator, wherein the separator further includes a protective layer formed on an upper section and/or a lower section thereof and the protective layer includes a sheet-shaped metal oxide nanosheet in a monolayer or multilayer 2D structure.
H01M 10/42 - Procédés ou dispositions pour assurer le fonctionnement ou l'entretien des éléments secondaires ou des demi-éléments secondaires
H01M 50/451 - Séparateurs, membranes ou diaphragmes caractérisés par le matériau ayant une structure en couches comprenant des couches de matériau organique uniquement et des couches comprenant un matériau inorganique
H01M 50/403 - Procédés de fabrication des séparateurs, des membranes ou des diaphragmes
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Lim, Jun Hyun
Abrégé
The present invention relates to a method for manufacturing a membrane-electrode assembly and a membrane-electrode assembly manufactured thereby, and more specifically, to a method for manufacturing a membrane-electrode assembly by using a nano-dispersed ionomer binder under supercritical conditions in a mixed solvent comprising alcohol and water, and a membrane-electrode assembly manufactured thereby and a fuel cell or water electrolysis device comprising same.
C25B 9/23 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes comprenant des membranes échangeuses d'ions dans ou sur lesquelles est incrusté du matériau pour électrode
C25B 11/095 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un des composés est de type organique
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
43.
USE OF NEOGENIN AS MARKER FOR DIAGNOSING BRAIN DAMAGE INDUCED BY EPILEPSY
THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Cho, Kyung-Ok
Kim, Hee Jung
Lee, Jae Ho
Choi, In-Young
Shim, Jae Hyuk
Kim, Mi-Hye
Kim, Yu Jin
Abrégé
The present invention relates to a use of neogenin as a marker for diagnosing brain damage induced by epilepsy. Since truncated neogenin increases when brain damage is induced by epilepsy, a composition according to the present invention can be used to easily and quickly diagnose the brain damage induced by epilepsy, and can be utilized as a target for developing a therapeutic agent for diseases caused by brain damage.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/558 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet utilisant la diffusion ou la migration de l'anticorps ou de l'antigène
A61K 31/221 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine avec des composés ayant un groupe amino, p. ex. acétylcholine, acétylcarnitine
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Heo, Pil Won
Lee, Sung Chul
Kang, Eun Heui
Choi, Seung Kyu
Jeong, Ki Young
Lee, Chang Hyun
Park, In Kee
Abrégé
The polymer electrolyte membrane includes: a first ion conductive polymer layer; and a second ion conductive polymer layer disposed on at least one surface of the first ion conductive polymer layer, wherein the first ion conductive polymer layer comprises a first ion conductive polymer comprising a sulfonic acid group, wherein the second ion conductive polymer layer comprises a second ion conductive polymer comprising a carboxylic acid group, and wherein a thickness of the second ion conductive polymer layer is in a range of 1% to 80% of a thickness of the polymer electrolyte membrane. Further, disclosed are the method for preparing the same, the membrane-electrode assembly including the same, and the fuel cell including the same.
H01M 8/1053 - Composites ou mélanges à électrolyte polymère constitués de couches de polymères dont au moins une couche est conductrice ionique
H01M 8/1039 - Matériaux d’électrolyte polymère halogénés, p. ex. des fluorures de polyvinylidène sulfonés
H01M 8/1072 - Matériaux d’électrolyte polymère caractérisés par le procédé de fabrication par des réactions chimiques, p. ex. polymérisation in situ ou réticulation in situ
H01M 8/1086 - Post-traitement de la membrane autrement que par polymérisation
45.
Chemically modified anion exchange membrane and method of preparing the same
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (USA)
Inventeur(s)
Lee, Chang Hyun
Hwang, Jin Pyo
Abrégé
The present invention relates to a chemically modified anion exchange membrane and a method of preparing the same and, more particularly, an anion exchange membrane in which sulfonic acid groups in a perfluorinated sulfonic acid electrolyte membrane are substituted with anion conductive groups such as ammonium group, phosphonium group, imidazolium group, pyridinium group and sulfonium group, and a method of preparing an anion exchange membrane by chemically modifying sulfonic acid groups in a perfluorinated sulfonic acid electrolyte membrane.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Park, Sunghyouk
Bae, Sang Hoon
Abrégé
The present invention relates to a composition containing lonafarnib as an active ingredient for prevention or treatment of sarcopenia. In the present invention, lonafarnib is identified to have an effect of alleviating the atrophy of myotubes formed from myoblasts and as such, is provided as a novel medication for prevention, treatment, or alleviation of sarcopenia.
A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
47.
COMPOSITION CONTAINING 6-METHOXYNICOTINAMIDE AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF SARCOPENIA
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Park, Sunghyouk
Bae, Sang Hoon
Abrégé
The present invention relates to a composition containing 6-methoxynicotinamide as an active ingredient for prevention or treatment of sarcopenia. In the present invention, 6-methoxynicotinamide is identified to have an effect of alleviating the atrophy of myotubes formed from myoblasts, and thus is provided as a novel medication for prevention, treatment, or alleviation of sarcopenia.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
GRAPHENE SQUARE INC. (République de Corée)
Dankook University Cheonan Campus Industry Academic Cooperation Foundation (République de Corée)
Inventeur(s)
Hong, Byung Hee
Kim, Dong Jin
Woo, Yun Sung
Abrégé
A method of evaluating quality of graphene using a confocal laser scanning microscope, the method comprising steps of: irradiating with laser light a graphene layer formed on a catalyst layer; detecting a signal of light reflected from the graphene layer; forming a planar image of the graphene layer using the detected optical signal; and analyzing a contrast between graphene and the catalyst layer in the planar image, wherein the graphene layer is continuously formed on the catalyst layer by a roll-to-roll process.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Woo, Seung Hoon
Abueva, Celine
Bae, Jun Sang
Ryu, Hyun Seok
Chung, Pil Sang
Eom, Joo Beom
Park, So Young
Abrégé
The present invention provides a hemostatic composition comprising N,N,N-trimethyl chitosan and povidone iodine. Since the hemostatic composition of the present invention comprises N,N,N-trimethyl chitosan and povidone iodine at the same time, the hemostatic composition may exhibit hemostatic performance due to the positive charge of the N,N,N-trimethyl chitosan and at the same time exhibit sterilization performance due to the povidone iodine. In addition, since the N,N,N-trimethyl chitosan and the povidone iodine form an ionic complex on the basis of the negative charge of iodine, it is possible to control the release rate of iodine in the hemostatic composition in a stable form.
A61K 47/55 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique l’agent de modification étant aussi un agent pharmacologiquement ou thérapeutiquement actif, c.-à-d. le conjugué entier étant un co-médicament, p. ex. un dimère, un oligomère ou un polymère de composés pharmacologiquement ou thérapeutiquement actifs
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61P 7/04 - AntihémorragiquesProfacteurs de coagulationAgents hémostatiquesAgents antifibrinolytiques
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chilwon
Kim, Kyoung Wan
Kim, Eun Bi
Abrégé
An organic light-emitting material according to the present invention has a dibenzo derivative introduced at the ortho position of benzene to have a high triplet energy and, particularly, provides a bipolar host through the introduction of a dibenzo derivative and a carbazole or amine derivative to ensure the balance of carrier injection and transport, and thus can achieve high luminous efficiency and long lifespan.
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
51.
METHOD FOR PREPARING HIGHLY-DISPERSIBLE RADICAL SCAVENGER METAL OXIDE-IONOMER NANOCOMPOSITE BY USING SELF-ASSEMBLY PROCESS AND FUEL CELL COMPRISING NANOCOMPOSITE PREPARED THEREBY
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Abrégé
The present invention relates to: a method for preparing a nanocomposite of an ionomer and a metal oxide acting as a radical scavenger; and a fuel cell comprising a nanocomposite prepared thereby and, more specifically, to: a method for preparing a highly-dispersible radical scavenger metal oxide-ionomer nanocomposite which can be redispersed to the size of nanoparticles in an aqueous alcohol solution or an ionomer solution; and a membrane electrode assembly and fuel cell comprising a nanocomposite prepared thereby.
C08J 3/21 - Formation de mélanges de polymères avec des additifs, p. ex. coloration en présence d'une phase liquide le polymère étant prémélangé avec une phase liquide
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Nam Choon
Joo, Sang Hyun
Hong, Jin Pyo
Abrégé
The present invention relates to a downtown-type bug house which can provide habitats for a plurality of target insects in partitioned spaces in one bug house, is easily installed, allows broken components to be easily replaced, and can be easily expanded in lateral directions. The bug house comprises a housing provided with: a wall body portion which has a pseudo-cylindrical shape surrounding the lateral portions of the partitioned internal spaces and has side surface openings for opening the partitioned internal spaces laterally, and in which concave circumferential portions and convex circumferential portions are coupled to form a concave circumferential surface at one side of the wall body portion; and a stopper portion which is installed on at least one of the upper end and the lower end of the wall body portion and blocks at least one of an upper end opening and a lower end opening of the wall body portion.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Nam Choon
Seol, Gu Ho
Jung, Gyu Jong
Abrégé
The present invention relates to an underdrain-type ecological corridor pipe which can provide moisture into an underdrain-type ecological corridor over a long period of time and maintain a fixed distance between the outer peripheral surface of an inner pipe body and the inner peripheral surface of an outer pipe body to keep a moisture-containing material from being compressed, thereby preventing degradation of the water content of the moisture-containing material. The underdrain-type ecological corridor pipe comprises: an inner pipe body having both ends open, having an ecological corridor for amphibians formed along the inner side, and having a plurality of first through holes, for enabling the communication between the inner peripheral surface and outer peripheral surface, at an interval; a moisture-containing material surrounding the outer peripheral surface of the inner pipe body and for providing moisture to the ecological corridor via the plurality of first through holes; and an outer pipe body surrounding the moisture-containing material.
E02D 29/00 - Ouvrages souterrains ou sous l'eauMurs de soutènement
F16L 21/06 - Raccords avec manchon ou douille avec manchon ou segment fractionné bridé autour des extrémités du tuyau
F16B 2/08 - Brides ou colliers, c.-à-d. dispositifs de fixation dont le serrage est effectué par des forces effectives autres que la résistance à la déformation inhérente au matériau dont est fait le dispositif externes c.-à-d. agissant par contraction utilisant des frettes ou des bandes
54.
STANDALONE BIRDHOUSE ASSEMBLY AND RING BODY THEREFOR
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Nam Choon
Lee, Seung Yong
Eo, Yang Joon
Abrégé
The present invention relates to a standalone birdhouse assembly which enables easy installation of a birdhouse in a place having no tree or building, such as a grassy place, and thus is outstanding for use in providing artificial birdhouses to birds and can reliably prevent natural enemies such as snakes from entering bird nests. The standalone birdhouse assembly comprises: a base member which is installed on the ground and made of a heavyweight material; a post member which is fixed on the base member and extends upward therefrom; and a birdhouse which is installed at the top of the post member and has an entrance formed therein.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Se Hwan
Abrégé
A bladder monitoring device and a urine discharge system using same are disclosed. The bladder monitoring device comprises: a light emitting unit for emitting near-infrared (NIR) rays having multiple wavelengths to the bladder; a light detecting unit for measuring reflection signal intensity for each wavelength of optical signals reflected and diffused from the bladder and configured to comprise a plurality of optical sensors sequentially disposed away from the light emitting unit; and a control unit for calculating reflectance by using the measured reflection signal intensity, calculating light absorbance by using the calculated reflectance, and calculating a water content in the bladder by using the calculated light absorbance, thereby calculating the amount of urine.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Hae Won
Kang, Min Sil
Jin, Guang Zhen
Park, Jeong Hui
Seo, Jung Ju
Lee, Jung Hwan
Lee, Hae Hyoung
Knowles, Jonathan
Abrégé
The present invention relates to a nano-cement comprising copper-bioactive glass nanoparticle (Cu-BGn), wherein the nano-cement can deposit hydroxyapatite in a simulated body fluid (SBF) comprising magnesium, calcium, and phosphate ions. The present invention provides a nano-cement having an antimicrobial effect against bacterial infection of tissue as well as tissue regeneration by doping Cu ions on bioactive nanoparticles having effects of angiogenesis and bone formation, and a preparing method therefor.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC (République de Corée)
POSTECH ACADEMY-INDUSTRY FOUNDATION (République de Corée)
Inventeur(s)
Ree, Moon Hor
Kwon, Kyung Ho
Ryu, Won Yeong
Han, Kwan Young
Lim, Sung Kyoo
Park, Byung Min
Jang, Dong Hoon
Kim, Hyun Joong
Kim, Hong Chul
Kim, Jeong Rae
Abrégé
The present invention relates to a polyvinyl-based compound, which maximizes self-healing ability by introducing various functional molecules into a brush of a polyvinyl-based resin, a preparation method thereof, and a polymer coating film produced therefrom.
C09D 133/14 - Homopolymères ou copolymères d'esters d'esters contenant des atomes d'halogène, d'azote, de soufre ou d'oxygène en plus de l'oxygène du radical carboxyle
C08J 7/046 - Formation de revêtements résistants à l'abrasionFormation de revêtements de durcissement de surface
C08F 220/28 - Esters contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle ne contenant pas de cycles aromatiques dans la partie alcool
C09D 133/06 - Homopolymères ou copolymères d'esters d'esters ne contenant que du carbone, de l'hydrogène et de l'oxygène, l'atome d'oxygène faisant uniquement partie du radical carboxyle
C09D 133/08 - Homopolymères ou copolymères d'esters de l'acide acrylique
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
KOREA INSTITUTE OF MACHINERY & MATERIALS (République de Corée)
Inventeur(s)
Oh, Se Heang
Kim, Min Ji
Kim, Ho Yong
Noh, Ha Yeon
Park, Su A
Byun, June Ho
Lee, Jin Ho
Abrégé
The present invention relates to: a porous polymer synthetic scaffold prepared using 3D printing, the scaffold being formed from fibers, stacked in a lattice shape, that have, on the basis of the diameter of the fibers, a leaf-stacked porous structure on the surface thereof and up to a depth of 1-50% from the surface and that have a nonporous structure from the depth to the center thereof; a manufacturing method for the scaffold; and a 3D printed porous synthetic scaffold in which cells and bioactive factors are loaded on the porous polymer synthetic scaffold, which is prepared using 3D printing and has the leaf-stacked structure.
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
POSTECH ACADEMY-INDUSTRY FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Park, Sung-Min
Abrégé
An electrode for acquiring a peripheral nerve signal, according to an embodiment of the present invention, which is invasively fixed to a peripheral nerve of a user to acquire a peripheral nerve signal, comprises: a support portion attached to the outer membrane of the peripheral nerve of the user; a plurality of needle electrodes having ends fixed to the support portion and the other ends invasively fixed to the peripheral nerve to acquire signals of a plurality of nerve branches in the peripheral nerve; and a wireless communication unit for wirelessly transmitting the signals acquired by the plurality of needle electrodes, wherein the plurality of needle electrodes may be formed to have different lengths.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chilwon
Lee, Takjae
Ha, Taehoon
Choi, Huijae
Abrégé
The present invention relates to a compound for an organic light emitting diode, an organic light emitting diode using same, and an electronic apparatus comprising the organic light emitting diode. The present invention can achieve delayed fluorescence and has reduced non-radiative decay due to the strong molecular structure thereof, thus improving the quantum efficiency of an organic light emitting diode, and has a high glass transition temperature and enhanced molecular stability, thus improving service life.
C07D 403/10 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)
61.
ORGANIC MATERIAL AND ORGANIC LIGHT EMITTING DIODE CONTAINING SAME
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chilwon
Jung, Dongki
Han, Mini
Abrégé
The present invention relates to a compound for an organic light emitting diode, an organic light emitting diode using same, and an electronic device comprising the organic light emitting diode. According to the present invention, it is possible to realize delayed fluorescence. In addition, the quantum efficiency of the organic light emitting diode is improved since radiationless decay is reduced due to a robust molecular structure. Moreover, the high glass transition temperature and the stability of molecules are enhanced, such that the lifespan can be improved.
C07D 401/10 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
C07D 403/10 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
C07D 405/12 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)
62.
COMPOSITION CONTAINING GABAPENTINOID FOR NERVE REGENERATION OR NERVE REHABILITATION OF INDIVIDUAL WITH SPINAL CORD INJURY
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Kim, Min Soo
Hong, Jin Young
Yoon, Kyung Wook
Kim, Young Jin
Kim, Seo Young
Seo, Kyung Chun
Abrégé
The present invention provides a composition containing a gabapentinoid as an active ingredient for nerve regeneration or nerve rehabilitation of an individual with spinal cord injury.
A61K 31/195 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino
A61K 31/197 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino les groupes amino et carboxyle étant liés à la même chaîne carbone acyclique, p. ex. acide gamma-aminobutyrique [GABA], bêta-alanine, acide epsilon-aminocaproïque ou acide pantothénique
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
63.
Method of preparing ion-exchange membrane using chemical modification and ion-exchange membrane prepared thereby
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (USA)
Inventeur(s)
Lee, Chang Hyun
Oh, Chang Hoon
Hwang, Jin Pyo
Abrégé
The present inventive concept relates to a method of preparing an ion-exchange membrane using a chemical modification and an ion-exchange membrane prepared thereby. More specifically, the present inventive concept relates to a method of preparing an ion-exchange membrane, which is characterized by modifying sulfonic acid groups of a perfluorinated sulfonic acid electrolyte membrane with carboxyl groups and includes chlorinating sulfonic acid groups of a perfluorinated sulfonic acid electrolyte membrane; nitrilating the chlorinated electrolyte membrane; and hydrolyzing the nitrilated electrolyte membrane, and an ion-exchange membrane chemically modified thereby.
A61K 36/65 - Paeoniaceae (famille de la pivoine), p. ex. pivoine chinoise
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 19/10 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget de l'ostéoporose
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
65.
Method of preparing chemically modified anion exchange membrane
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (USA)
Inventeur(s)
Lee, Chang Hyun
Hwang, Jin Pyo
Abrégé
The present inventive concept relates to a chemically modified anion exchange membrane and a method of preparing the same and, more particularly, an anion exchange membrane in which sulfonic acid groups in a perfluorinated sulfonic acid electrolyte membrane are substituted with anion conductive groups such as ammonium group, phosphonium group, imidazolium group, pyridinium group and sulfonium group, and a method of preparing an anion exchange membrane by chemically modifying sulfonic acid groups in a perfluorinated sulfonic acid electrolyte membrane.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Jangsub
Lee, Chilwon
Han, Kwanyoung
Abrégé
The present invention relates to luminescent nanocrystals and, to luminescent nanocrystals using an electronically delocalized carbamate derivative, the luminescent nanocrystals being substituted with a carbamate ligand, which has a strong coordination ability and has an electrically resonant structure, so as to adjust an exciton Bohr radius, thereby enabling the size of the nanocrystals to be precisely controlled.
C09K 11/02 - Emploi de substances particulières comme liants, revêtements de particules ou milieux de suspension
C09K 11/08 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes
C09K 11/88 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du sélénium, du tellure ou des chalcogènes non spécifiés
67.
LAMINATION METHOD FOR ENABLING FOUR-SIDED EDGE-TYPE WINDOW SUBSTRATE HAVING CORNERS ON ALL SIDES TO DISPLAY ON CORNERS AND LAMINATION APPARATUS THEREFOR
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Han, Kwanyoung
Abrégé
The present invention relates to a lamination method and a lamination apparatus therefor, which enable even the corners on all sides of an edge-type display window substrate to be smoothly laminated such that display and touch functions may be implemented on the corners.
B32B 37/10 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par la technique de pressage, p. ex. faisant usage de l'action directe du vide ou d'un fluide sous pression
B32B 3/02 - Caractérisés par des caractéristiques de forme en des endroits déterminés, p. ex. au voisinage des bords
68.
COMPOSITION COMPRISING CIMICIFUGA DAHURICA EXTRACT, FRACTION THEREOF, OR CIMICIFUGA DAHURICA-DERIVED COMPOUND AS EFFECTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF DEGENERATIVE BRAIN DISEASE
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Yang, Hyun Ok
Kim, Young Ho
Park, So-Young
Chun, Yoon Sun
Zhang, Li Jun
Lee, Sang-Bin
Park, Jeong Yun
Abrégé
The present invention relates to a pharmaceutical composition comprising a Cimicifuga dahurica extract or a compound isolated therefrom as an effective ingredient for prevention or treatment of degenerative brain disease, a method for prevention or treatment of degenerative brain disease by using the pharmaceutical composition, and a food composition and an animal feed composition for prevention or alleviation of degenerative brain disease. A Cimicifuga dahurica extract or a compound isolated therefrom according to the present invention is characterized by specifically increasing an amount of a protein involved in autophagy. In detail, the Cimicifuga dahurica extract or the compound isolated therefrom upregulates the expression of LC3 protein, which is a membrane protein of autophagosomes, exhibits an superior effect of downregulating the expression of mTOR protein inhibitory of autophagy, and furthermore has an excellent effect of suppressing the production of beta-amyloid, which is a dementia-causing material, and the impairment of memory, thus finding effective applications in treating degenerative brain disease, such as Parkinson's disease, Alzheimer's disease, and dementia, and alleviating cognitive impairment.
A61K 36/71 - Ranunculaceae (famille du bouton d'or), p. ex. pied d'alouette, hépatique, hydrastis, ancolie
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
69.
DEVICE AND METHOD FOR FOLDING/UNFOLDING TEST CAPABLE OF EVALUATING RELIABILITY OF FOLDABLE SUBSTRATE QUANTITATIVELY
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Han, Kwanyoung
Abrégé
The present invention relates to a folding/unfolding test device capable of evaluating reliability of a foldable substrate quantitatively, wherein a foldable substrate is folded/unfolded by rotating a support substrate leftward/rightward/upward/downward, folding characteristics can be precisely measured while reflecting the radius (R) at the part that bends when same is utilized as a product, and it is possible to measure the exact number of foldings that initiates abrupt degradation. A folding/unfolding test device according to the present invention comprises: a folding/unfolding portion having two support substrates configured in a rotating type so as to support a foldable substrate; a light measurement/detection portion having a light emitter positioned above a folded part for quantitative evaluation and having a light detector positioned below the folding portion so as to measure the amount of light in real time or according to predetermined folding/unfolding number designation; a surface measurement portion having a microscope positioned on the upper end of the folding portion so as to automatically measure the surface according to the folding/unfolding number designation; and a control portion. Accordingly, real-time quantitative measurement of folding/unfolding evaluation of a foldable substrate is possible.
G01M 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
G01N 3/32 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant des efforts répétés ou pulsatoires
G01N 21/95 - Recherche de la présence de criques, de défauts ou de souillures caractérisée par le matériau ou la forme de l'objet à analyser
Dankook University Cheonan Campus Industry Academic Cooperation Foundation (République de Corée)
Inventeur(s)
Jung, Kyung Ho
Park, Byung Min
Han, Kwan Young
Abrégé
A display device including: a display panel; a cover plate disposed on the display panel; and an adhesive layer disposed between the display panel and the cover plate, wherein the adhesive layer includes a main adhesive layer and a thin film layer, the thin film layer includes a first thin film layer and a second thin film layer disposed on the first thin film layer, the first thin film layer contains a siloxane functional group and the second thin film layer contains fluorine, and the second thin film layer is disposed between the first thin film layer and the cover plate.
H01L 51/52 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED) - Détails des dispositifs
H01L 51/56 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
B32B 7/12 - Liaison entre couches utilisant des adhésifs interposés ou des matériaux interposés ayant des propriétés adhésives
B32B 37/12 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par l'usage d'adhésifs
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
H01L 27/32 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des composants qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux avec des composants spécialement adaptés pour l'émission de lumière, p.ex. panneaux d'affichage plats utilisant des diodes émettrices de lumière organiques
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Misook
Lee, Sae Rom
Jeong, Yoonhwa
Abrégé
Leuconostoc mesenteroidesLeuconostoc mesenteroides MKSR deposited as Accession No. KCTC13842BP and a use thereof. Specifically, the present invention relates to a novel Leuconostoc mesenteroides strain, a health functional food for preventing or improving diabetes containing the strain, a health functional food for improving cholesterol containing the strain, a pharmaceutical composition for preventing or treating diabetes containing the strain, a pharmaceutical composition for preventing or treating hyperlipidemia containing the strain, and a food additive.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Rhee, Yun Hee
Choi, Young Hoon
Moon, Jeong Hwan
Park, So Young
Chung, Phil Sang
Abrégé
The present invention relates to an apparatus and method for non-invasive irradiation of light stimulating salivary glands, wherein the salivary glands are stimulated by non-invasive irradiation of light thereto, thereby reducing inconvenience to a patient and causing no side effects.
Dankook University Cheonan Campus Industry Academic Cooperation Foundation (République de Corée)
Inventeur(s)
Jang, Young Joo
Kang, Kyung Jung
Abrégé
The present invention relates to a composition for the differentiation of dental pulp stem cells into odontoblasts and an IgG or IgM type monoclonal antibody that specifically binds to the surface of odontoblasts differentiated from the stem cells. According to the present invention, BMP2 and BMP4 are optimally combined to significantly increase the differentiation efficiency of dental pulp stem cells into odontoblasts, to induce the mineralization of the matrix, and to improve the differentiation ability of odontoblasts into dentin. Further, the IgG or IgM monoclonal antibody that specifically binds to the surface of odontoblasts of the present invention is used to effectively isolate and purify odontoblasts, which can be useful for tissue regeneration and differentiation.
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
C07K 16/18 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
74.
Separator for lithium secondary battery, method for manufacturing same, and lithium secondary battery including same
Samsung Electronics Co., Ltd. (République de Corée)
Dankook University Cheonan Campus Industry Academic Cooperation Foundation (République de Corée)
Inventeur(s)
Yang, Seung Rim
Lee, Chang Hyun
Han, Sung Soo
Park, Myungkook
Cho, Minho
Abrégé
The present invention relates to a separator for a lithium secondary battery, a method for manufacturing the separator, and a lithium secondary battery including the separator. The separator includes a porous substrate and a heat resistance porous layer positioned on at least one surface of the porous substrate, wherein the heat resistance porous layer includes a sulfonic acid group-containing polysulfone.
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p. ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 50/40 - SéparateursMembranesDiaphragmesÉléments d’espacement dans les cellules
H01M 50/403 - Procédés de fabrication des séparateurs, des membranes ou des diaphragmes
H01M 50/409 - Séparateurs, membranes ou diaphragmes caractérisés par le matériau
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Young Ik
Eom, Sang Hoon
Park, Sang Hyo
Kang, Dong Bum
Han, Kwan Young
Abrégé
A display unit separating method according to the present invention comprises: a step of withdrawing a display unit seated on a cooling jig by opening a cooling door; and a step in which a glass separation unit injects gas to a separating gap between one side of an optical adhesive layer and a cover glass so as to separate the optical adhesive layer and the cover glass.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Hyung Gun
Abrégé
The present invention relates to a method for screening a pain-inhibiting substance, said method comprising the steps of: (a) inserting a microdialysis probe into the L1 site of a spinal cord dorsal horn of a neuropathic pain animal model; (b) collecting a first test sample from the L1 site by microdialysis; (c) administering a pain-inhibiting candidate substance into the body of the animal model; (d) after having administered the pain-inhibiting candidate substance, then collecting a second test sample from the L1 site by microdialysis; (e) measuring the concentrations of a pain indicator substance in the first test sample and second test sample respectively; and (f) comparing the concentrations of the pain indicator substance in the first test sample and second test sample.
77.
POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
78.
CIRCUIT AND METHOD FOR DETECTING PRESSURE SIGNAL WITH SIGNAL DUE TO PYROELECTRICITY IN PIEZOELECTRIC MATERIAL BEING SUPPRESSED
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
DAIKIN INDUSTRIES, LTD. (Japon)
Inventeur(s)
Kim, Hyunsik
Kanemura, Takashi
Kodani, Tetsuhiro
Han, Kwan-Young
Abrégé
The present invention relates to a circuit and a method for detecting a pressure signal in which a signal due to pyroelectricity from a piezoelectric film is suppressed. In more detail, an input signal from a piezoelectric film is received, the input signal is differentiated in order to analyze a signal component of the input signal, an analysis value of the signal component of the input signal is output on the basis of the differentiated value, the analysis value of the signal component is used to eliminate an offset of the input signal, and the input signal is integrated to output a value of the input signal due to pressure from which a value of the input signal due to heat has been removed. Therefore, compared to the prior art, the present invention can detect the input signal at a higher speed while significantly reducing the effect caused by a thermal reaction. Furthermore, the present invention can output a signal having an even better thermal reaction damping effect than that obtained by using an additional process for absorbing heat during the manufacture of a piezoelectric film.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Shin, Ueon Sang
Kim, Han Sem
Abrégé
The present invention relates to a membrane including a metal substrate layer and a CNT/chitosan nanohybrid coating layer, and an electrostatic dust collection system including the same. The membrane of the present invention has excellent electrical conductivity and is thus capable of efficiently collecting dust, even with a low current, and has excellent mechanical strength and is thus suitable for application in various types of electrostatic dust collection systems.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Shin, Ueon Sang
Kim, Han Sem
Abrégé
The present invention relates to a membrane including a porous substrate layer and a CNT/chitosan nanohybrid coating layer, and an electrostatic dust collection system including the same. The membrane of the present invention has excellent electrical conductivity and is thus capable of efficiently collecting dust, even with a low current. Moreover, the membrane has pores such that air is able to pass through the membrane freely, and the path by which the air passes through the membrane is long, and thus it is possible to collect a large amount of dust. In addition, the membrane of the present invention can be manufactured in various forms and is thus suitable for application in various types of electrostatic dust collection systems.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Woo Byoung
Choi, Jae Young
Park, Hyun Su
Abrégé
Provided are an electrostatic chuck sealed with a sealant and a method for manufacturing same. The sealant contains a polysilazane and is for sealing a thermally sprayed layer of an electrostatic chuck. The sealant can form pure SiO2 at the same time as sealing a thermally sprayed layer of an electrostatic chuck, even at a low temperature. Therefore, since an electrostatic chuck sealed with the sealant has excellent acid resistance, the lifespan of the electrostatic chuck can be extended and electrical properties including withstand voltage and insulation resistance can be improved.
H01L 21/683 - Appareils spécialement adaptés pour la manipulation des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide pendant leur fabrication ou leur traitementAppareils spécialement adaptés pour la manipulation des plaquettes pendant la fabrication ou le traitement des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide ou de leurs composants pour le maintien ou la préhension
H01L 21/324 - Traitement thermique pour modifier les propriétés des corps semi-conducteurs, p. ex. recuit, frittage
H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
C09K 3/10 - Substances non couvertes ailleurs pour sceller ou étouper des joints ou des couvercles
82.
METHOD FOR MANUFACTURING ION EXCHANGE MEMBRANE USING CHEMICAL MODIFICATION AND ION EXCHANGE MEMBRANE MANUFACTURED THEREBY
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Oh, Chang Hoon
Hwang, Jin Pyo
Abrégé
The present invention relates to a method for manufacturing an ion exchange membrane using chemical modification and an ion exchange membrane manufactured thereby and, more specifically, to a method for manufacturing an ion exchange membrane using chemical modification and an ion exchange membrane chemically modified by the method, the method being characterized in that a sulfonic acid group of a perfluorinated sulfonic acid electrolyte membrane is modified with a carbonic acid group, the method comprising the steps of: subjecting a sulfonic acid group of a perfluorinated sulfonic acid electrolyte membrane to a chlorination reaction; subjecting the electrolyte membrane subjected to the chlorination reaction to a nitrilation reaction; and subjecting the electrolyte membrane subjected to the nitrilation reaction to a hydrolysis reaction.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Hwang, Jin Pyo
Abrégé
The present invention relates to a chemically modified anion exchange membrane and a manufacturing method therefor and, more specifically, to an anion exchange membrane in which a sulfonic acid group of a perfluorinated sulfonic acid electrolyte membrane is modified with an anion conductive functional group, such as an ammonium group, a phosphonium group, an imidazolium group, a pyridium group, or a sulfonium group, and to a manufacturing method for an anion exchange membrane by chemically modifying a sulfonic acid group of a perfluorinated sulfonic acid electrolyte membrane.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
POSTECH ACADEMY-INDUSTRY FOUNDATION (République de Corée)
Inventeur(s)
Ree, Moon Hor
Kwon, Kyung Ho
Ryu, Won Yeong
Han, Kwan Young
Lim, Sung Kyoo
Park, Byung Min
Jang, Dong Hoon
Kim, Hyun Joong
Kim, Hong Chul
Kim, Jeong Rae
Abrégé
The present invention relates to a polyvinyl-based compound, which maximizes self-healing ability by introducing various functional molecules into a brush of a polyvinyl-based resin, a preparation method thereof, and a polymer coating film produced therefrom.
C08F 220/18 - Esters des alcools ou des phénols monohydriques des phénols ou des alcools contenant plusieurs atomes de carbone avec l'acide acrylique ou l'acide méthacrylique
C08F 220/30 - Esters contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle contenant des cycles aromatiques dans la partie alcool
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Abrégé
Disclosed are: an ionomer nanoparticle dispersion solution formed by dispersing a perfluorinated ionomer having an ion conductive functional group in a solvent mixture including water and an alcohol, and carrying out a reaction under a supercritical condition; and a preparation method thereof. The ionomer nanoparticle dispersion solution has a high azeotropic mixture content in a continuous phase, which is a liquid phase, so as to readily remove a solvent therefrom, and thus a product using the ionomer nanoparticle dispersion solution can be readily fabricated and preparation costs can be reduced. In addition, uniformity of the product is improved because a perfluorinated ionomer having various ion conductive functional groups and various salts thereof is nano-dispersed, in a narrow molecular weight distribution, in the ionomer nanoparticle dispersion solution.
C09D 127/18 - Homopolymères ou copolymères du tétrafluoro-éthylène
C08J 3/09 - Production de solutions, dispersions, latex ou gel par d'autres procédés que ceux utilisant les techniques de polymérisation en solution, en émulsion ou en suspension dans des liquides organiques
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (USA)
Inventeur(s)
Choi, Yong
Abrégé
Disclosed is a method of manufacturing various alloy thin films, in which nano-scale cracks are controlled, with desired compositions using an ultrasonic pulse electroforming process. The method includes a step of forming a multilayer that includes two or more different thin metal film layers, in which nano-scale cracks due to hydrogen generation are controlled, a step of ultimately facilitating interdiffusion by controlling the thickness of the multilayer to a nano-scale thickness through pulse application and the number of layers forming the multilayer, and controlling an alloy to have a desired composition through heat treatment, and a step of thermally treating the multilayer such that interdiffusion sufficiently occurs among the two or more different thin metal film layers. The step of thermally treating may be carried out along with rolling, whereby very fine cracks may be removed by compression and, accordingly, alloy foils having various compositions may be economically produced. A layer number and thickness of the multilayer may be controlled to a nano-sized thickness by applying various types of pulses or by connecting a plurality of electrolytic cells in series and stepwise or repeatedly transferring adding an electroforming layer to the electrolytic cells under a DC application condition.
C25D 5/14 - Dépôt de plusieurs couches du même métal ou de métaux différents au moins une couche étant du nickel ou du chrome plusieurs couches étant du nickel ou du chrome, p. ex. couches doubles ou triples
C25D 5/18 - Dépôt au moyen de courant modulé, pulsé ou inversé
C25D 5/50 - Post-traitement des surfaces revêtues de métaux par voie électrolytique par traitement thermique
C22F 1/08 - Modification de la structure physique des métaux ou alliages non ferreux par traitement thermique ou par travail à chaud ou à froid du cuivre ou de ses alliages
C23F 17/00 - Procédés à étapes multiples pour le traitement de surface de matériaux métalliques utilisant au moins un procédé couvert par la classe et au moins un procédé couvert soit par la sous-classe , soit par la sous-classe , soit par la classe
C25D 3/20 - Dépôt électrochimiqueBains utilisés à partir de solutions de fer
C25D 3/12 - Dépôt électrochimiqueBains utilisés à partir de solutions de nickel ou de cobalt
C25D 3/38 - Dépôt électrochimiqueBains utilisés à partir de solutions de cuivre
C25D 3/58 - Dépôt électrochimiqueBains utilisés à partir de solutions d'alliages contenant plus de 50% en poids de cuivre
87.
COMPOSITION FOR DIFFERENTIATION OF DENTAL PULP STEM CELLS INTO ODONTOBLAST PROGENITOR CELLS AND IGG OR IGM TYPE MONOCLONAL ANTIBODY SPECIFICALLY BINDING TO SURFACE OF ODONTOBLAST PROGENITOR CELLS
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Jang, Young Joo
Kang, Kyung Jung
Abrégé
The present invention relates to a composition for differentiation of dental pulp stem cells into odontoblast progenitor cells and an IgG or IgM type monoclonal antibody specifically binding to the surface of the odontoblast progenitor cells differentiated from the dental pulp stem cells. According to the present invention, when BMP2 and BMP4 are treated in combination at an optimal ratio, the differentiation efficiency of the dental pulp stem cells into the odontoblast progenitor cells is significantly increased, the calcification of a matrix is induced, and the ability of the odontoblast progenitor cells to be differentiated into dentin is enhanced. In addition, when an IgG or IgM monoclonal antibody that specifically binds to the surface of the odontoblast progenitor cells of the present invention is employed, the odontoblast progenitor cells that can be usefully used for tissue regeneration and differentiation can be effectively isolated and purified.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
C12N 5/12 - Cellules fusionnées, p. ex. hybridomes
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
88.
ENTECAVIR DERIVATIVE COMPOUND BOUND WITH FATTY ACID AND PHARMACEUTICAL USE THEREOF
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kang, Myung Joo
Han, Young Taek
Lee, Dae Ro
Ho, Myoung Jin
Abrégé
The present invention relates to an entecavir derivative compound bound with a fatty acid and a pharmaceutical use thereof. The entecavir derivative covalently bound with a fatty acid according to the present invention exhibits a significantly lower solubility and dissolution rate than entecavir. The fatty acid polymer of entecavir according to the present invention can exert a sustained effect for several weeks or more after a single administration when a preparation is made for parenteral administration such as an injection, and can drastically improve patient medication compliance .
C07D 473/18 - Composés hétérocycliques contenant des systèmes cycliques purine avec des atomes d'oxygène, de soufre ou d'azote liés directement en positions 2 et 6 un atome d'oxygène et un atome d'azote, p. ex. guanine
A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Hyun, Jung Keun
Park, Ilyong
Kim, Min Soo
Kim, Hyeongbeom
Yoon, Kyeong Wook
Abrégé
The present disclosure provides an apparatus generating spinal cord contusive model of animals, including an external fixation member fixed outside a body of an experiment animal, an impactor configured to impart a spinal cord of the experiment animal, and an impactor guide member fixed to the external fixation member to guide a fall of the impactor, wherein the impactor is provided with an acceleration sensor.
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Yang, Seung Rim
Lee, Chang Hyun
Han, Sung Soo
Park, Myungkook
Cho, Minho
Abrégé
The present invention relates to a separator for a lithium secondary battery, a method for manufacturing the separator, and a lithium secondary battery including the separator. The separator includes a porous substrate and a heat resistant porous layer positioned on at least one surface of the porous substrate, wherein the heat resistant porous layer includes a sulfonic acid group-containing polysulfone.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p. ex. LiNiO2, LiCoO2 ou LiCoOxFy
91.
COMPOSITION FOR TREATMENT OF OSTEOARTHRITIS COMPRISING HYALURONIC ACID AND MAGNESIUM
DANKOOK UNIVERSITY CHEONAN CAMPUS, INDUSTRY-ACADEMIC COOPERATION FOUNDATION (République de Corée)
GL PHARMTECH CORP. (République de Corée)
Inventeur(s)
Kang, Myung Joo
Ho, Myoung Jin
Lee, Dae Ro
Jung, Hyuck Jun
Park, Jun Sang
Song, Woo Heon
Oh, Jin Seob
Abrégé
Disclosed is a pharmaceutical composition for treating osteoarthritis comprising hyaluronic acid or a pharmaceutically acceptable salt thereof or a hydrate thereof and magnesium or a pharmaceutically acceptable salt thereof and a hydrate thereof.
Dankook University Cheonan Campus Industry Academic Cooperation Foundation (République de Corée)
Inventeur(s)
Lee, Han-A-Reum
Kim, Ho-Yong
Park, Jin-Hyun
Byun, June-Ho
Lee, Jin-Ho
Oh, Se-Heang
Abrégé
The present invention relates to: a porous polymer material having a porous structure over the entire polymer and having a dense porous structure in which pores are connected to each other therein. The porous polymer material is harmless to the human body as it does not use toxic organic solvents. In addition, a porous polymer material can be prepared without using any additives for forming pores and the particle size can be easily controlled, and thus a polymer material suitable for various uses can be prepared. Furthermore, the extended release of a loaded bioactive material is possible only by the dense porous structure of a polymer itself without using an additive and a surface modification method in the porous polymer material of the present invention. Therefore, the porous polymer material can be applied to a biodegradable material in various bio-fields requiring the extended release of a bioactive material.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 31/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
93.
SELF-HEALING POLYETHER COMPOUND AND PREPARATION METHOD THEREFOR
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
POSTECH ACADEMY-INDUSTRY FOUNDATION (République de Corée)
Inventeur(s)
Ree, Moon Hor
Kwon, Kyung Ho
Lee, Jin Seok
Song, Sung Jin
Han, Kwan Young
Lim, Sung Kyoo
Park, Byung Min
Jang, Dong Hoon
Kim, Hyun Joong
Kim, Hong Chul
Kim, Joung Rae
Abrégé
The present invention relates to: a polyether compound having a self-healing function, represented by chemical formula 1 and having a weight average molecular weight of 5,000-5,000,000, preferably 5,000-500,000; a preparation method therefor; and a polymer thin film formed therefrom. The polyether compound having a self-healing function, used in the present invention, is an economical material facilitating processing and capable of being readily coated on various substrates, and thus manufacturing a polymer thin film by using the polyether compound having a self-healing function is simple. In addition, the polymer thin film can repair micro-damage on the surface thereof by means of the self-healing characteristics of the polyether and, particularly, recovery ability is maximized and repeated effective recovery is possible by using a self-healing functional molecule.
C08G 65/26 - Composés macromoléculaires obtenus par des réactions créant une liaison éther dans la chaîne principale de la macromolécule à partir d'éthers cycliques par ouverture d'un hétérocycle à partir d'éthers cycliques et d'autres composés
C08G 65/323 - Polymères modifiés par post-traitement chimique avec des composés inorganiques contenant des halogènes
C08G 65/332 - Polymères modifiés par post-traitement chimique avec des composés organiques contenant de l'oxygène contenant des groupes carboxyle, ou leurs halogénures ou esters
C08G 65/333 - Polymères modifiés par post-traitement chimique avec des composés organiques contenant de l'azote
94.
POLYMER REGENERATION MEMBRANE AND PREPARATION METHOD THEREFOR
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, Jin Hyun
Lee, Jin Ho
Oh, Se Heang
Abrégé
The present invention relates to: a leaf-stacked guided bone regeneration membrane having a membrane layer with a small average pore size at an upper part thereof and having a leaf-stacked structure in the inside and lower part thereof; and a preparation method therefor. The present invention is harmless to the human body since toxic organic materials are not used, and a guided bone regeneration membrane having a leaf-stacked structure can be manufactured by a simple method. In addition, according to the present invention, the leaf-stacked guided bone regeneration membrane allows the sustained release of a bioactive factor only by means of a leaf-stacked structure without using any additive and surface modification method, thereby being very effective in bone regeneration.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Park, So-Young
Joo, Hwan-Bin
Abrégé
The present invention relates to a phloroglucinol-based compound and a use of a salt thereof for preventing and treating Alzheimer's dementia. The pharmaceutical composition for preventing or treating Alzheimer's dementia of the present invention fundamentally suppresses a cause of beta-amyloid formation, thereby exerting a remarkable effect of allowing a fundamental treatment for Alzheimer's dementia. The present invention provides an initial use of a single material, which has been isolated from Dryopteris crassirhizoma and identified, for preventing or treating Alzheimer's dementia.
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Choi, Yong
Abrégé
Disclosed is a method for producing various alloy thin films having desired compositions and controlled nanoscale cracks therein by means of an ultrasonic pulse electroforming process. Said method comprises the steps of: forming multi-layers comprising two or more different metallic thin-film layers having therein nanoscale cracks, which are caused by hydrogen, controlled; controlling, by pulse application, the thickness of the multi-layers on a nanoscopic scale and the number of the multi-layers so as to ultimately promote interdiffusion and control the multi-layers to have desired alloy compositions through heat treatment; and heat-treating the multi-layers so that the interdiffusion between the two or more different metallic thin-film layers is sufficiently generated. The heat treatment step is carried out together with rolling, thereby removing ultrafine cracks by compression and thus economically producing alloy foils having various compositions. The number and thickness of the multi-layers may be controlled in terms of a nanoscale thickness through the application of various kinds of pulses or controlled by serially connecting multiple electrolytic cells and moving/introducing an electroforming layer to the multiple electrolytic cells in stages or repeatedly under the condition of direct current application.
C25D 3/12 - Dépôt électrochimiqueBains utilisés à partir de solutions de nickel ou de cobalt
C25D 3/38 - Dépôt électrochimiqueBains utilisés à partir de solutions de cuivre
C25D 5/10 - Dépôt de plusieurs couches du même métal ou de métaux différents
C25D 5/12 - Dépôt de plusieurs couches du même métal ou de métaux différents au moins une couche étant du nickel ou du chrome
C25D 5/14 - Dépôt de plusieurs couches du même métal ou de métaux différents au moins une couche étant du nickel ou du chrome plusieurs couches étant du nickel ou du chrome, p. ex. couches doubles ou triples
C25D 5/18 - Dépôt au moyen de courant modulé, pulsé ou inversé
C25D 5/50 - Post-traitement des surfaces revêtues de métaux par voie électrolytique par traitement thermique
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chang Hyun
Abrégé
Disclosed are: an ionomer nanoparticle dispersion solution formed by dispersing, in a solvent mixture, which comprises water and an alcohol, a perfluorinated ionomer, which has an ion conductive functional group, and carrying out a reaction under a supercritical condition; and a preparation method therefor. The ionomer nanoparticle dispersion solution has a high azeotropic mixture content in a continuous phase, which is a liquid phase, so as to readily remove a solvent therefrom, and thus a product using the ionomer nanoparticle dispersion solution can be readily molded and preparation costs can be reduced. In addition, product uniformity is improved since a perfluorinated ionomer having various ion conductive functional groups and various salts thereof is nano-dispersed, in a narrow molecular weight distribution, in the ionomer nanoparticle dispersion solution.
C08J 3/02 - Production de solutions, dispersions, latex ou gel par d'autres procédés que ceux utilisant les techniques de polymérisation en solution, en émulsion ou en suspension
98.
BONE REGENERATING SCAFFOLD COATED WITH EXTRACELLULAR MATRIX
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
POSTECH ACADEMY-INDUSTRY FOUNDATION (République de Corée)
T&R BIOFAB CO., LTD. (République de Corée)
Inventeur(s)
Yang, Hee Seok
Cho, Dong Woo
Jang, Jin Ah
Kim, Byoung Soo
Lee, Min Suk
La, Wan Geun
Abrégé
The present invention relates to a bone regenerating scaffold comprising: a first layer comprising polycaprolactone (PCL), poly(D,L-lactic-co-glycolic acid) (PLGA) and β-tricalcium phosphate (TCP); and a second layer comprising a demineralised and decellularised bone extracellular matrix (bdECM), wherein the second layer surrounds the first layer; and to a production method for same. The bone regenerating scaffold coated with extracellular matrix of the present invention allows scaffold production in a shape that accurately matches an affected area where bone damage has been incurred by means of a 3D printer, and, as compared with existing scaffolds, can be expected to have the advantage of relatively rapid bone regeneration through more rapid fusing to the affected area and better attachment, growth and bone differentiation of surrounding bone tissue cells. Also, because there is no need for steps such as cell transplantation, bone-damaged patients can be expected to recover relatively rapidly by implanting the scaffold within a short time.
A61L 27/46 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges inorganiques contenant du phosphore
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
99.
PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CENTRAL NERVOUS SYSTEM DISEASE
GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Choi, Yong-Mun
Ahn, Sang-Mee
Ku, Jin-Mo
Park, Kyu-Hee
Nam, Yeon-Ju
Lee, Jung-Hun
Jeong, Dae-Youn
Cho, Kyong-Jin
Km, Yu-Han
Yoon, Sung-Hwa
Park, Ju-Young
Kwon, Soon-Jeong
Abrégé
The present invention relates to an amide derivative compound or a pharmaceutically acceptable salt thereof. Also, the present invention relates to a pharmaceutical composition for treating or preventing central nervous system disease, the composition comprising the compound or the pharmaceutically acceptable salt thereof.
C07C 311/16 - Sulfonamides ayant des atomes de soufre de groupes sulfonamide liés à des atomes de carbone de cycles aromatiques à six chaînons ayant l'atome d'azote d'au moins un des groupes sulfonamide lié à des atomes d'hydrogène ou à un atome de carbone acyclique
C07D 263/56 - BenzoxazolesBenzoxazoles hydrogénés avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement en position 2
C07D 277/64 - Benzothiazoles avec uniquement des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués liés en position 2
EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (République de Corée)
THE ASAN FOUNDATION (République de Corée)
DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Yoon-Keun
Kim, You-Sun
Jee, Young Koo
Oh, Yeon-Mok
Cho, You Sook
Choi, Jun-Pyo
Abrégé
The present invention relates to a method for diagnosing inflammatory respiratory diseases using outer membrane vesicles derived from bacteria and, more specifically, to a method for diagnosing asthma, chronic obstructive pulmonary disease, and lung cancer by measuring specific antibodies to outer membrane vesicles derived from bacteria existing in indoor dust or to proteins derived from the outer membrane vesicles. The outer membrane vesicles derived from Staphylococcus spp., Acinetobacter spp., Pseudomonas spp., and Enterobacter spp., which exist in large quantities in dust in the indoor air, may cause inflammatory respiratory diseases, and thus the present invention can be favorably used as a method for diagnosing asthma, chronic obstructive pulmonary disease, and lung cancer, by measuring specific antibodies to outer membrane vesicles/proteins derived from the bacteria in patient samples.
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer