A method for modulating the electrical synchronization of the cerebral cortex within safe limits by computing the orientation of the applied currents with respect to the orientation of the cortical surface and thus cortical columns. Ongoing electroencephalographic monitoring, including the synchronization of induced with stimulating currents, may confirm the precision and safety of the applied currents.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
2.
ELECTRIC MARKOV BLANKET FOR A BRAIN-COMPUTER CRITICALITY BRIDGE
An electric Markov blanket (eMb) system and method for establishing a Brain-Computer Criticality Bridge (BCCB) are disclosed. Electrophysiological signals are acquired from an organism, decomposed to obtain cross-frequency coupling metrics indexing excitatory-inhibitory criticality, and assembled into a Criticality Vector that fully characterizes the organism's electric Markov blanket. The Criticality Vector may be stored, analyzed, reproduced in vivo via patterned neuromodulation, or instantiated in silico or other informatic medium to create a personal neuromorphic emulation. Embodiments include ethical-control mechanisms ensuring user sovereignty and safety. The invention enables clinical interventions, cognitive enhancement, and personal-identity preservation.
A method for modulating the electrical synchronization of the cerebral cortex within safe limits by computing the orientation of the applied currents with respect to the orientation of the cortical surface and thus cortical columns. Ongoing electroencephalographic monitoring, including the synchronization of induced with stimulating currents, may confirm the precision and safety of the applied currents.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
4.
METHOD FOR BAYESIAN SUPER-RESOLUTION OF ELECTROENCEPHALOGRAPHIC SOURCE ANALYSIS AND TRANSCRANIAL ELECTRICAL STIMULATION
A method for achieving super-resolution in localizing electrical fields measured at the head surface with electroencephalography through a generative model of the cerebral cortex that has a very high resolution of cortical surface dipoles constructed from the known properties of human cerebral cortex and adapted to optimize the Bayesian explanation the individual's cortical surface electrical fields. The iterative optimization of the prior (generative) with the posterior (observed) fields with extensive data from extended recordings provides a probabilistic estimation of the individual's functional brain activity that can be used to train artificial neural network approximations of the individual's mental activity.
A method for controlling the behavior of Large Language Models (LLMs) based on the principles of active inference that are integral to human natural language behavior and are thereby manifest implicitly by LLMs. These principles are similar to the actor component of control systems that achieve optimal behavior when conditions of the system's fit to the environment are known and feedforward control is best, compared to more uncertain conditions when close feedback from external criteria is needed to guide behavior optimally by the external evidence. The structured prompting of LLMs then achieves the single optimal response for both the generative creativity of the LLM response and the accuracy and control of the response through alternating, and then integrating, the contextual prompts according to these principles.
The Neuromorphic Emulation Constructor AI (NECA) is an artificial intelligence technology for building a Personal Neuromorphic Emulation (PNE), a detailed model of an individual's brain that is anatomically correct, capable of learning and plasticity, and able to emulate the person's brain electrical activity and behavior. The NECA accesses the neuroscience literature through automated search and acquisition technologies such as Google Scholar, and it assembles the knowledge of the brain's structure and function in ways that specify how to build and test the PNE.
G06N 3/063 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens électroniques
A semi-dry electrode for a neural sensor net. The electrode may comprise an electrolyte storage medium for storing electrolyte, a body portion including an electrolyte reservoir for receiving the bottom surface of the electrolyte storage medium, a cap connected to the body portion for at least partially covering the top surface of the electrolyte storage medium so as to prevent contact between the top surface of the electrolyte storage medium and a person's finger(s), and a vibrating device for vibrating the electrode so as to release electrolyte from the electrolyte storage medium out through the body portion.
A method for treating anxiety disorders may include applying a first pair of electrodes on the left side of a subject's head and a second pair of electrodes on the right side of the subject's head; applying a first stimulus carrier of a first magnitude to the first pair of electrodes and a second stimulus carrier of a second magnitude to the second pair of electrodes, wherein the first and second stimulus carriers combine to produce a stimulus having a frequency between 1 Hz and 1 kHz; and steering the stimulus toward the subject's left amygdala.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
Medical devices for treating sleep disorders, namely, wearable headband with electrodes to track EEG sleep staging and provide electrical stimulation for sleep therapy
10.
Truncated icosahedral neural sensor net and modular elements therefor
A truncated icosahedral neural sensor net and modular elements therefor. The neural sensor net comprises a plurality of substantially pentagonally shaped elements connected to each other with elongate elastic tension lines at their respective vertices, the tension lines defining therebetween a plurality of substantially hexagonally shaped elements. The neural sensor net may be assembled from a plurality of modular elements.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Downloadable software for EEG (electroencephalogram) analysis and source localization; Downloadable cloud-based software for EEG (electroencephalogram) analysis and source localization
15.
Method for desynchronizing pathological neural oscillations
A method for desynchronizing a pathological neural oscillations, includes identifying a first subpopulation of the neurons involved in the pathological neural oscillation that are in alignment with each other within a predetermined angular stimulation range, and a second subpopulation that are both (A) in alignment with each other within the predetermined angular stimulation range, and (B) out of alignment with the first neurons by at least the predetermined angular stimulation range, and applying electrical stimuli to the first and second subpopulations through scalp electrodes, the electrical stimuli being out of phase with the pathological neural oscillations for desynchronizing the pathological neural oscillations.
A61B 5/053 - Mesure de l'impédance ou de la conductivité électrique d'une partie du corps
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
