INSTITUTE OF RHEOLOGICAL FUNCTIONS OF FOOD (Japon)
Inventeur(s)
Fujino, Takehiko
Mawatari, Shiro
Abrégé
A method for manufacturing a functional material that contains plasmalogen, the method including treating an animal tissue containing plasmalogen with protease, and extracting the animal tissue treated with protease with an extraction liquid containing ethanol.
A61K 35/57 - OiseauxSubstances provenant des oiseaux, p. ex. œufs, plumes, blanc d’œuf, jaune d’œuf ou endothelium corneum gigeriae galli
A61K 31/685 - Diesters d'acide du phosphore avec deux composés hydroxyle, p. ex. phosphatidylinositols un des composés hydroxylés ayant des atomes d'azote, p. ex. phosphatidylsérine, lécithine
A61K 35/655 - Animaux aquatiques autres que ceux couverts par les groupes
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61K 35/618 - Mollusques, p. ex. mollusques d’eau douce, huîtres, palourdes, calmars, poulpes, seiches, escargots ou limaces
C12P 13/00 - Préparation de composés organiques contenant de l'azote
INSTITUTE OF RHEOLOGICAL FUNCTIONS OF FOOD (Japon)
Inventeur(s)
Fujino, Takehiko
Mawatari, Shiro
Kawa, Tsunemichi
Koyama, Tetsuji
Yamashita, Toyoharu
Abrégé
A method for assessing aging of erythrocytes that includes preparing an erythrocyte suspension from a blood sample; allowing the erythrocyte suspension to pass through a first filter, separating aged erythrocytes that do not pass through the first filter, and non-aged erythrocytes that pass through the first filter, and to calculate a deformability of erythrocytes, allowing the separated non-aged erythrocyte suspension to pass through a second filter having micropores which diameter is smaller than the first filter, separating mild aged erythrocytes that do not pass through the second filter and juvenile erythrocytes that pass through the second filter, and to calculate a deformability of the non-aged erythrocytes; and assessing aging of erythrocytes, using the deformability of erythrocyte and the deformability of non-aged erythrocyte.
G01N 15/10 - Recherche de particules individuelles
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
4.
ORAL COMPOSITION FOR STRESS REDUCTION AND/OR BODY WEIGHT RECOVERY, AND METHOD FOR PRODUCING PLASMALOGEN-CONTAINING COMPOSITION
INSTITUTE OF RHEOLOGICAL FUNCTIONS OF FOOD (Japon)
Inventeur(s)
Fujino Takehiko
Mawatari Shiro
Abrégé
A method for producing a plasmalogen-containing functional material, said method comprising an enzymatic treatment step for treating an animal tissue containing plasmalogen with a protease, and an extraction step for extracting the protease-treated animal tissue with an extractant containing ethanol.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
C11B 11/00 - Obtention ou raffinage d'autres matières grasses, p. ex. lanoline ou cires
6.
METHOD FOR EVALUATING DEGREE OF AGING IN RED BLOOD CELLS
INSTITUTE OF RHEOLOGICAL FUNCTIONS OF FOOD (Japon)
Inventeur(s)
Fujino Takehiko
Mawatari Shiro
Kawa Tsunemichi
Koyama Tetsuji
Yamashita Toyoharu
Abrégé
[Problem] To provide a method for evaluating the degree of aging in red blood cells that can more precisely and accurately evaluate the degree of aging in red blood cells. [Solution] A method for evaluating the degree of aging in red blood cells, the method comprising: a red blood cell suspension preparation step (S1) for preparing a red blood cell suspension from a blood sample; a first red blood cell deformability calculation step (S2) for calculating the deformability of red blood cells and passing the red blood cell suspension through a first filter to separate the suspension into aged red blood cells that do not pass through the first filter and non-aged red blood cells that do pass through the first filter; a second red blood cell deformability calculation step (S3) for calculating the deformability of the non-aged red blood cells and passing the separated non-aged red blood cell suspension through a second filter, which has micropores of a smaller diameter compared to the first filter, to separate the suspension into mildly aged red blood cells that do not pass through the second filter and young red blood cells that do pass through second first filter; and an evaluation step (S4) for using the deformability of the red blood cells and the deformability of the non-aged red blood cells to evaluate the degree of aging in the red blood cells.
INSTITUTE OF RHEOLOGICAL FUNCTIONS OF FOOD (Japon)
Inventeur(s)
Fujino Takehiko
Mawatari Shiro
Yamashita Toyoharu
Kitamura Mitsuru
Okauchi Tatsuo
Hossain Shamim
Abrégé
A compound represented by general formula (I), a racemic form thereof, or a salt of the compound or the racemic form. (In general formula (I), X represents an oxygen atom, a nitrogen atom, a sulfur atom or a carbon atom; R1represents R1a-Y-R1b(wherein each of R1aand R1brepresents a saturated or unsaturated aliphatic hydrocarbon group, an aromatic group, a heterocyclic group, or a group obtained by combining these groups; and Y represents an oxygen atom, a nitrogen atom, a sulfur atom or a carbon atom); each R2represents a saturated or unsaturated aliphatic hydrocarbon group; and R3 represents choline, ethanolamine, inositol or serine.)
A61K 31/683 - Diesters d'acide du phosphore avec deux composés hydroxyle, p. ex. phosphatidylinositols
A61K 31/685 - Diesters d'acide du phosphore avec deux composés hydroxyle, p. ex. phosphatidylinositols un des composés hydroxylés ayant des atomes d'azote, p. ex. phosphatidylsérine, lécithine
A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
[PROBLEM TO BE SOLVED] It enables any superior ether phospholipids to the conventional ones and a method for producing the same in an easy manner on a massive scale, in light of effects of treating and improving brain diseases such as Alzheimer's disease, Parkinson disease, depression and schizophrenia, metabolic diseases such as diabetes, various infectious diseases, and immune disorders. [SOLUTION] Ether phospholipids are obtained from bivalve tissues such as clams and corbicula by extraction processing. The ether phospholipids exhibit significantly superior effects of the above as compared to the conventional ether phospholipids derived from chicken tissues.
A23J 7/00 - Compositions à base de phosphatides pour l'alimentation, p. ex. lécithine
A61K 31/685 - Diesters d'acide du phosphore avec deux composés hydroxyle, p. ex. phosphatidylinositols un des composés hydroxylés ayant des atomes d'azote, p. ex. phosphatidylsérine, lécithine
C11B 11/00 - Obtention ou raffinage d'autres matières grasses, p. ex. lanoline ou cires
A61K 35/618 - Mollusques, p. ex. mollusques d’eau douce, huîtres, palourdes, calmars, poulpes, seiches, escargots ou limaces
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