40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Custom manufacturing services using a proprietary technology
platform for capsule and any other oral solid dosage forms,
and encapsulation technologies. Scientific and technological consulting services in the
field of pharmaceutical development, specifically for the
formulation, customization and encapsulation of capsules and
other oral solid dosage forms; scientific and technological
consulting services for creating and providing capsule and
any other oral solid dosage form delivery solutions;
scientific and technological consulting services in relation
to capsule and any other oral solid dosage form expertise;
product development services using a proprietary technology
platform for capsule and any other oral solid dosage forms,
and encapsulation technologies.
3.
FILM-FORMING COMPOSITION CONTAINING SURFACTANT OR SURFACTANT AND SALT AS WHITENING AGENT
[Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide.
[Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide.
[Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.
A61K 8/46 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant du soufre
A61K 8/65 - Collagène; Gélatine; Kératine; Leurs dérivés ou produits de dégradation
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Custom manufacturing services using a proprietary technology platform for capsule and any other oral solid dosage forms, and encapsulation technologies. Scientific and technological consulting services in the field of pharmaceutical development, specifically for the formulation, customization and encapsulation of capsules and other oral solid dosage forms; scientific and technological consulting services for creating and providing capsule and any other oral solid dosage form delivery solutions; scientific and technological consulting services in relation to capsule and any other oral solid dosage form expertise; product development services using a proprietary technology platform for capsule and any other oral solid dosage forms, and encapsulation technologies.
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Custom manufacturing services of products, using a proprietary technology platform for capsule and any other oral solid dosage forms, and encapsulation technologies. Scientific and technological consulting services in the field of pharmaceutical development, specifically for the formulation, customization, and encapsulation of capsules and other oral solid dosage forms; scientific and technological consulting services for creating and providing capsule and any other oral solid dosage form delivery solutions; scientific and technological consulting services in relation to capsule and any other oral solid dosage form expertise; product development services using a proprietary technology platform for capsule and any other oral solid dosage forms, and encapsulation technologies.
6.
GRAVURE PRINTING CYLINDER FOR PRINTING OF LARGE-SIZED TAGS
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Presentation of goods on communication media, for retail
purposes; retail and wholesale services for pharmaceutical
and nutraceutical preparations; online retail store services
relating to pharmaceutical and nutraceutical preparations;
online advertising on a computer network; provision of
online advertising, marketing services and business
information via a website; online ordering services;
providing commercial information to consumers; provision of
information and advice to consumers regarding the selection
of products and items to be purchased. Providing temporary use of non-downloadable software
applications accessible via a website; providing online,
non-downloadable software; hosting of platforms and portals
on the Internet; hosting of interactive applications;
providing temporary use of non-downloadable computer
software to enable sharing of multimedia content and
comments among users; providing temporary use of web-based
applications and software; providing temporary use of
on-line non-downloadable single sign-on software; providing
temporary use of on-line non-downloadable software for the
transmission and management of data; platform as a service
(PaaS); software as a services (SaaS); administration of
user rights in computer networks; user authentication
services using technology for e-commerce transactions;
computer programming services for the analysis of data;
technical data analysis services.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Presentation of goods on communication media, for retail purposes; retail and wholesale services for pharmaceutical and nutraceutical preparations; online retail store services relating to pharmaceutical and nutraceutical preparations; online advertising on a computer network; provision of online advertising, marketing services and business information via a website; online ordering services; providing commercial information to consumers; provision of information and advice to consumers regarding the selection of products and items to be purchased.
(2) Providing temporary use of non-downloadable software applications accessible via a website; providing online, non-downloadable software; hosting of platforms and portals on the Internet; hosting of interactive applications; providing temporary use of non-downloadable computer software to enable sharing of multimedia content and comments among users; providing temporary use of web-based applications and software; providing temporary use of on-line non-downloadable single sign-on software; providing temporary use of on-line non-downloadable software for the transmission and management of data; platform as a service (PaaS); software as a services (SaaS); administration of user rights in computer networks; user authentication services using technology for e-commerce transactions; computer programming services for the analysis of data; technical data analysis services.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Presentation of goods on communication media, for retail purposes; retail and wholesale services for pharmaceutical and nutraceutical preparations; online retail store services relating to pharmaceutical and nutraceutical preparations; online advertising on a computer network; provision of online advertising, marketing services and business information via a website; online ordering services; providing commercial information to consumers; provision of information and advice to consumers regarding the selection of products and items to be purchased. Providing temporary use of non-downloadable software applications accessible via a website; providing online, non-downloadable software; hosting of platforms and portals on the Internet; hosting of interactive applications; providing temporary use of non-downloadable computer software to enable sharing of multimedia content and comments among users; providing temporary use of web-based applications and software; providing temporary use of on-line non-downloadable single sign-on software; providing temporary use of on-line non-downloadable software for the transmission and management of data; platform as a service (PaaS); software as a services (SaaS); administration of user rights in computer networks; user authentication services using technology for e-commerce transactions; computer programming services for the analysis of data; technical data analysis services.
The present disclosure is directed to an oil-in-water emulsion containing at least one hygroscopic ingredient and an edible oil. The emulsion has a water activity of less than about 0.6. The emulsion may be incorporated into an oral dosage form, including a capsule oral dosage form. The ingredients provided in the emulsion are capable of improving the health or well-being of a human or animal.
Presentation of goods on communication media, on an Ecommerce online platform, for retail purposes; retail services for pharmaceutical and nutraceutical preparations; online retail store services relating to pharmaceutical and nutraceutical preparations.
[Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide.
[Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide.
[Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.
A61K 8/46 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant du soufre
A61K 8/65 - Collagène; Gélatine; Kératine; Leurs dérivés ou produits de dégradation
The present invention discloses a sealing fluid comprising an organic acid, an alcohol and optionally water, the organic acid is lactic acid or acetic acid, the alcohol is isopropanol or ethanol, the sealing fluid is a liquid composition for sealing telescopically joined hard capsules with coaxial partly overlapping body parts.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Liquid filled medical preparation capsules for a wide variety of pharmaceuticals for pharmaceutical use; liquid filled diet capsules for use with nutritional supplements, all of the foregoing sold exclusively business to business
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Empty capsules for pharmaceutical use; gelatin capsules sold empty for pharmaceuticals for use with nutritional supplements; all of the foregoing sold exclusively business to business
The invention discloses double layered delayed-release hard capsules made by double dipping, that is by two consecutive dip molding steps on the same mold pin without removing the film, provided by the first dip molding step, from the mold pin between the two dip molding steps, but dipping the mold pin with this first film in the second dip molding step, each dip molding step is done with a different polymer melt, providing a double layered delayed-release capsule.
The present invention relates to a device for dispensing a single droplet of a fluid, for example a single droplet of an adhesive, onto the inside surface of a cap or onto the inside surface of a body of a capsule, this is useful for rendering a closed capsule with a telescopically engaged cap and body more tamperproof, or for fixing a cap or a body or both, which encloses a caplet or tablet or a part thereof, to the caplet or the tablet.
B65B 39/00 - Ajutages, entonnoirs ou guides pour introduire des objets ou matériaux dans les réceptacles ou les emballages
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
B65B 7/28 - Fermeture de réceptacles ou récipients semi-rigides ou rigides, non déformés par le contenu ou n'en prenant pas la forme, p.ex. boîtes ou cartons en appliquant des fermetures séparées préformées, p.ex. couvercles, capuchons
B65B 51/02 - Application d'adhésifs ou de liquides de scellement
B65B 51/10 - Application ou production de chaleur ou de pression ou les deux à la fois
B65B 51/32 - Refroidissement, ou refroidissement et compression, des fermetures des paquets, après thermosoudage
The present invention relates a dosing device, DOSDEV, for dosing solid particulate materialinto a receptacle, preferably into a capsule, the DOSDEV has a dosing element which has a tube shape which can be filled with the solid particulate material by sucking in the solid particulate material by means of a vacuum and wherein excess solid particulate material sticking to the entrance of the DOSDEV is blown off with gas.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
B65B 1/04 - Procédés ou moyens pour remplir les réceptacles ou les récipients avec le matériau
G01F 1/00 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu
30.
METHOD FOR MAKING MULTIPARTICULATES FROM A LIQUID FEED EMPLOYING A SPINNING DISC SPRAYER
A process for making multiparticulates, comprising providing a molten feed comprising an active ingredient and an excipient, and providing a spinning disc sprayer comprising a rotating disc having a feed-receiving surface driven from above by a hollow drive shaft, wherein axes of rotation of the hollow drive shaft and rotatable disc are coaxial and a downward end of the hollow drive shaft is disposed with a distributor for regulating flow of the molten feed into the well, the distributor and the well together configured for providing a substantially radial, uniform outward flow of the molten feed across the feed-receiving surface.
B01J 2/02 - Procédés ou dispositifs pour la granulation de substances, en général; Traitement de matériaux particulaires leur permettant de s'écouler librement, en général, p.ex. en les rendant hydrophobes par division du produit liquide en gouttelettes, p.ex. par pulvérisation, et solidification des gouttelettes
B05B 3/10 - Appareillages de pulvérisation ou d'arrosage avec des éléments de sortie mobiles ou des éléments déflecteurs mobiles avec des éléments rotatifs avec évacuation sur la presque totalité de la périphérie de l'élément rotatif
31.
Single-use spray drying components and methods of using the same
Spray drying method and systems are disclosed that include one or more single-use components. Single-use spray drying systems can include a drying chamber with an inner surface formed of a polymeric material. The single-use components can be pre-sterilized and sterile packaged to provide improved efficiencies and greater operational flexibility in spray drying systems.
F26B 3/12 - Procédés de séchage d'un matériau solide ou d'objets impliquant l'utilisation de chaleur par convection, c. à d. la chaleur étant transférée d'une source de chaleur au matériau ou aux objets à sécher par un gaz ou par une vapeur, p.ex. l'air le gaz ou la vapeur entraînant le matériau ou les objets à sécher sous forme d'une pulvérisation
B01D 1/18 - SÉPARATION Évaporation par pulvérisation pour obtenir des solides secs
B05B 7/16 - Appareillages de pulvérisation pour débiter des liquides ou d'autres matériaux fluides provenant de plusieurs sources, p.ex. un liquide et de l'air, une poudre et un gaz comportant des moyens pour chauffer la matière à projeter
B05B 15/40 - Filtres situés en amont des sorties de pulvérisation
F26B 25/14 - Chambres, récipients ou réceptacles de structure simple
F26B 25/16 - Chambres, récipients ou réceptacles de structure simple quasi fermés, p.ex. tambours
A composition, such as a dietary composition is disclosed containing one or more capsaicinoids contained within a lipid matrix. In one embodiment, the composition contains a liquid capsaicin in addition to a capsaicin wax. The composition is formulated such that when is ingested does not break down in the stomach but instead releases the capsaicin in the small intestines for various dietary benefits, including appetite suppression.
The invention discloses hydroxypropyl methylcellulose (HPMC) capsules containing a small amount of CaCl2, which show reduced powder retention when used in Dry Powder Inhalers (DPI), and a method for making them.
The instant disclosure provides a capsule composition comprising pullulan, a setting system and a surfactant system that is a sucroglyceride or a sugar fatty acid ester, and methods for making such capsules.
Multiparticulate compositions including an active agent and a gelling agent are disclosed. The multiparticulate compositions are prepared by an aqueous-based spray and congeal process.
The present invention relates to a capsule shell with two parts, a cap and a body, the two parts engage telescopically with each other, the capsule shell is used for storing solid substances in powder or granular form and shows a minimized leakage rate of powder when the capsule shell is filled with the solid substances in powder form and is closed.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
A61K 9/48 - Préparations en capsules, p.ex. de gélatine, de chocolat
38.
Method and Composition for Increasing Muscle Protein Synthesis
A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid component including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in a solution with L-carnitine. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building z composition can be administered in a monolithic enteric capsule.
A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid derivative including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in an acid resistant capsule delivery form. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building composition can be administered in a monolithic enteric capsule.
A nozzle assembly includes a nozzle, a manifold, and wand body. The nozzle, manifold, and wand body can be coupled together to provide a robust spray drying system that can withstand elevated temperature and/or pressure feed stock. In some embodiments, an internal shoulder portion of the manifold can engage with a side of a nozzle collar to restrict distal movement of the nozzle relative to the manifold.
B05B 7/06 - Pistolets pulvérisateurs; Appareillages pour l'évacuation avec un orifice de sortie en entourant un autre situé approximativement dans le même plan
B05B 7/10 - Pistolets pulvérisateurs; Appareillages pour l'évacuation produisant une turbulence à la sortie
F26B 3/12 - Procédés de séchage d'un matériau solide ou d'objets impliquant l'utilisation de chaleur par convection, c. à d. la chaleur étant transférée d'une source de chaleur au matériau ou aux objets à sécher par un gaz ou par une vapeur, p.ex. l'air le gaz ou la vapeur entraînant le matériau ou les objets à sécher sous forme d'une pulvérisation
F26B 21/14 - Utilisation de gaz ou de vapeurs autres que l'air ou la vapeur d'eau
41.
Particles Containing a Lipid Matrix Core and Active Ingredient
A composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein is disclosed. The active ingredient can include a fat-soluble active ingredient. The particles can be contained in a capsule. Also provided are methods for producing a pharmaceutical composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein.
An aqueous composition for making dip-molded comestible hard capsules comprising a film forming capsule base material and one or more colorants each consisting of a hydrophilic coloring foodstuff concentrate.
B29C 41/00 - Façonnage par revêtement d'un moule, noyau ou autre support, c. à d. par dépôt de la matière à mouler et démoulage de l'objet formé; Appareils à cet effet
Ammonia is used as a processing aid in a method for forming a sprayed solid dispersion comprising an active agent, wherein the active agent, in a free acid form, has a pKa≤7 and a solubility≤40 mg/mL in the spray solvent. Ammonia is subsequently removed from the sprayed solid dispersion. Sprayed solid dispersions formed by the disclosed method are also disclosed.
A61K 31/655 - Composés azoïques(-N=N-), diazoïques (=N2), azoxy (N-O-N ou N(=O)-N), azido (-N3) ou diazoamino (-N=N-N)
A61K 31/5415 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p.ex. sulthiame condensés en ortho ou en péri avec des systèmes carbocycliques, p.ex. phénothiazine, chlorpromazine, piroxicam
The present disclosure is directed to an extended release composition containing Vitamin C in a lipid matrix, which releases the Vitamin C over a period of time.
A61K 31/375 - Acide ascorbique, c. à d. vitamine C; Ses sels
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
Problem to be solved: To provide a whitened or opacified capsule and film without using a white pigment such as titanium dioxide. Solution: A film, a capsule and a film-forming composition characterized by containing a film-forming polymer component selected from gelatin and pullulan and an opacifying agent consisting of a water-soluble salt except calcium salt carbonate and bicarbonate, wherein the salt is selected from a sodium salt, potassium salt, an ammonium salt and a magnesium salt.
The present invention discloses a sealing fluid comprising an organic acid, an alcohol and optionally water, the organic acid is lactic acid or acetic acid, the alcohol is isopropanol or ethanol, the sealing fluid is a liquid composition for sealing telescopically joined hard capsules with coaxial partly overlapping body parts.
A61J 1/00 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
A61K 9/48 - Préparations en capsules, p.ex. de gélatine, de chocolat
The invention discloses double layered delayed-release hard capsules made by double dipping, that is by two consecutive dip molding steps on the same mold pin without removing the film, provided by the first dip molding step, from the mold pin between the two dip molding steps, but dipping the mold pin with this first film in the second dip molding step, each dip molding step is done with a different polymer melt, providing a double layered delayed-release capsule.
The invention discloses double layered delayed-release hard capsules made by double dipping, that is by two consecutive dip molding steps on the same mold pin without removing the film, provided by the first dip molding step, from the mold pin between the two dip molding steps, but dipping the mold pin with this first film in the second dip molding step, each dip molding step is done with a different polymer melt, providing a double layered delayed-release capsule.
The present invention relates to a device DEV for dispensing a single droplet of a fluid, for example a single droplet of a adhesive, onto the inside surface of a cap or onto the inside surface of a body of a capsule, this is useful for rendering a closed capsule with a telescopically engaged cap and body more tamperproof, or for fixing a cap or a body or both, which encloses a caplet or tablet or a part thereof, to the caplet or the tablet.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets
B65B 51/02 - Application d'adhésifs ou de liquides de scellement
[Technical Problem] A problem of the present invention is, in one aspect, to provide a capsule formulation including an active ingredient and the like that may deteriorate upon contacting an acid, wherein the capsule formulation makes it possible not to deteriorate the active ingredient and the like by a gastric acid which enters into a capsule film.
[Technical Problem] A problem of the present invention is, in one aspect, to provide a capsule formulation including an active ingredient and the like that may deteriorate upon contacting an acid, wherein the capsule formulation makes it possible not to deteriorate the active ingredient and the like by a gastric acid which enters into a capsule film.
[Technical Solution] A capsule formulation comprising an active ingredient and oil, wherein said capsule of said formulation is an enteric capsule comprising a water soluble film forming polymer and gellan gum; said oil is an oil acceptable for pharmaceuticals or foods; and said active ingredient is encapsulated in said capsule together with said oil, and the production method thereof, are provided.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
A61K 9/48 - Préparations en capsules, p.ex. de gélatine, de chocolat
A61K 47/14 - Esters d’acides carboxyliques, p.ex. acides gras monoglycérides, triglycérides à chaine moyenne, parabènes ou esters d’acide gras de PEG
A61K 47/44 - Huiles, graisses ou cires couvertes par plus d’un des groupes ; Huiles, graisses ou cires naturelles ou naturelles modifiées, p.ex. huile de ricin, huile de ricin polyéthoxylée, cire de lignite, lignite, gomme-laque, colophane, cire d’abeille ou lanoline
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
B65B 3/04 - Procédés ou moyens pour charger le matériau dans les réceptacles ou récipients
B65B 7/28 - Fermeture de réceptacles ou récipients semi-rigides ou rigides, non déformés par le contenu ou n'en prenant pas la forme, p.ex. boîtes ou cartons en appliquant des fermetures séparées préformées, p.ex. couvercles, capuchons
B65D 65/46 - Emploi de matériaux désintégrables, solubles ou comestibles
A composition, such as a dietary composition is disclosed containing one or more capsaicinoids contained within a lipid matrix. In one embodiment, the composition contains a liquid capsaicin in addition to a capsaicin wax. The composition is formulated such that when is ingested does not break down in the stomach but instead releases the capsaicin in the small intestines for various dietary benefits, including appetite suppression.
A23D 7/00 - Compositions à base d'huiles ou de graisses comestibles, contenant une phase aqueuse, p.ex. margarines
A23L 27/10 - ALIMENTS, PRODUITS ALIMENTAIRES OU BOISSONS NON ALCOOLISÉES NON COUVERTS PAR LES SOUS-CLASSES OU ; LEUR PRÉPARATION OU TRAITEMENT, p.ex. CUISSON, MODIFICATION DES QUALITÉS NUTRITIVES, TRAITEMENT PHYSIQUE ; CONSERVATION DES ALIMENTS OU PRODUITS ALIMENTAIRES EN GÉNÉRAL Édulcorants artificiels; Sels de table; Substituts diététiques du sel; Leur préparation ou leur traitement Épices, agents aromatiques ou condiments naturels; Leurs extraits
A23L 33/00 - Modification de la qualité nutritive des aliments; Produits diététiques; Leur préparation ou leur traitement
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A23L 33/115 - Acides gras ou leurs dérivés; Graisses ou huiles
A23D 7/005 - Compositions à base d'huiles ou de graisses comestibles, contenant une phase aqueuse, p.ex. margarines caractérisées par des ingrédients autres que des triglycérides d'acides gras
A composition, such as a dietary composition is disclosed containing one or more capsaicinoids contained within a lipid matrix. In one embodiment, the composition contains a liquid capsaicin in addition to a capsaicin wax. The composition is formulated such that when is ingested does not break down in the stomach but instead releases the capsaicin in the small intestines for various dietary benefits, including appetite suppression.
A23D 7/00 - Compositions à base d'huiles ou de graisses comestibles, contenant une phase aqueuse, p.ex. margarines
A23D 7/005 - Compositions à base d'huiles ou de graisses comestibles, contenant une phase aqueuse, p.ex. margarines caractérisées par des ingrédients autres que des triglycérides d'acides gras
A23L 27/10 - ALIMENTS, PRODUITS ALIMENTAIRES OU BOISSONS NON ALCOOLISÉES NON COUVERTS PAR LES SOUS-CLASSES OU ; LEUR PRÉPARATION OU TRAITEMENT, p.ex. CUISSON, MODIFICATION DES QUALITÉS NUTRITIVES, TRAITEMENT PHYSIQUE ; CONSERVATION DES ALIMENTS OU PRODUITS ALIMENTAIRES EN GÉNÉRAL Édulcorants artificiels; Sels de table; Substituts diététiques du sel; Leur préparation ou leur traitement Épices, agents aromatiques ou condiments naturels; Leurs extraits
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A23L 33/115 - Acides gras ou leurs dérivés; Graisses ou huiles
A23L 33/00 - Modification de la qualité nutritive des aliments; Produits diététiques; Leur préparation ou leur traitement
60.
METHOD FOR MAKING MULTIPARTICULATES FROM A LIQUID FEED EMPLOYING A SPINNING DISC SPRAYER
A process for making multiparticulates, comprising providing a molten feed comprising an active ingredient and an excipient, and providing a spinning disc sprayer (100) comprising a rotating disc (110) having a feed-receiving surface (112) driven from above by a hollow drive shaft (A-A'), wherein axes of rotation of the hollow drive shaft (A-A') and rotatable disc (B-B') are coaxial and a downward end (22) of the hollow drive shaft (200) is disposed with a distributor (204) for regulating flow of the molten feed into the well (116), the distributor (204) and the well (116) together configured for providing a substantially radial, uniform outward flow of the molten feed across the feed-receiving surface (112).
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p.ex. poudres
B01J 2/02 - Procédés ou dispositifs pour la granulation de substances, en général; Traitement de matériaux particulaires leur permettant de s'écouler librement, en général, p.ex. en les rendant hydrophobes par division du produit liquide en gouttelettes, p.ex. par pulvérisation, et solidification des gouttelettes
B05B 3/10 - Appareillages de pulvérisation ou d'arrosage avec des éléments de sortie mobiles ou des éléments déflecteurs mobiles avec des éléments rotatifs avec évacuation sur la presque totalité de la périphérie de l'élément rotatif
61.
METHOD FOR MAKING MULTIPARTICULATES FROM A LIQUID FEED EMPLOYING A SPINNING DISC SPRAYER
A process for making multiparticulates, comprising providing a molten feed comprising an active ingredient and an excipient, and providing a spinning disc sprayer (100) comprising a rotating disc (110) having a feed-receiving surface (112) driven from above by a hollow drive shaft (A-A'), wherein axes of rotation of the hollow drive shaft (A-A') and rotatable disc (B-B') are coaxial and a downward end (22) of the hollow drive shaft (200) is disposed with a distributor (204) for regulating flow of the molten feed into the well (116), the distributor (204) and the well (116) together configured for providing a substantially radial, uniform outward flow of the molten feed across the feed-receiving surface (112).
B01J 2/02 - Procédés ou dispositifs pour la granulation de substances, en général; Traitement de matériaux particulaires leur permettant de s'écouler librement, en général, p.ex. en les rendant hydrophobes par division du produit liquide en gouttelettes, p.ex. par pulvérisation, et solidification des gouttelettes
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p.ex. poudres
B05B 3/10 - Appareillages de pulvérisation ou d'arrosage avec des éléments de sortie mobiles ou des éléments déflecteurs mobiles avec des éléments rotatifs avec évacuation sur la presque totalité de la périphérie de l'élément rotatif
This disclosure concerns oral pharmaceutical compositions comprising a solid dosage form (SDF). The SDF comprises (i) a solid amorphous dispersion (SAD) comprising a poorly water soluble active agent and a matrix material comprising poly[(methyl methacrylate)-co-(methacrylic acid)] (PMMAMA), and (ii) a concentration-sustaining polymer (CSP), wherein the CSP is not dispersed in the SAD, and the SAD is at least 35 wt % of the SDF. The SAD and CSP together may be at least 50 wt % of the SDF. The SDF may be, for example, a tablet, a caplet, or a capsule.
The invention discloses hydroxypropyl methylcellulose (HPMC) capsules containing a small amount of CaCl2, which show reduced powder retention when used in Dry Powder Inhalers (DPI), and a method for making them.
[Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide.
[Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.
A61K 8/46 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant du soufre
A61K 8/65 - Collagène; Gélatine; Kératine; Leurs dérivés ou produits de dégradation
The present disclosure relates to lipid-based formulations, lipid formulations or compositions comprising lipophilic salts and acidic pH modifiers. The acidic pH modifiers are able to yield stabilized lipid formulations and/or to increase the solubility of the lipophilic salts in the lipid formulations.
A composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein is disclosed. The active ingredient can include a fat-soluble active ingredient. The particles can be contained in a capsule. Also provided are methods for producing a pharmaceutical composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein.
A23L 5/00 - Préparation ou traitement des aliments ou produits alimentaires en général; Aliments ou produits alimentaires ainsi obtenus; Leurs matériaux
A61K 9/48 - Préparations en capsules, p.ex. de gélatine, de chocolat
The present invention relates to a capsule shell with two parts, a cap and a body, the two parts engage telescopically with each other, the capsule shell is used for storing solid substances in powder or granular form and shows a minimized leakage rate of powder when the capsule shell is filled with the solid substances in powder form and is closed.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
The present invention relates to a capsule shell with two parts, a cap and a body, the two parts engage telescopically with each other, the capsule shell is used for storing solid substances in powder or granular form and shows a minimized leakage rate of powder when the capsule shell is filled with the solid substances in powder form and is closed.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
A nozzle assembly includes a nozzle, a manifold, and wand body. The nozzle, manifold, and wand body can be coupled together to provide a robust spray drying system that can withstand elevated temperature and/or pressure feed stock. In some embodiments, an internal shoulder portion of the manifold can engage with a side of a nozzle collar to restrict distal movement of the nozzle relative to the manifold.
F26B 3/12 - Procédés de séchage d'un matériau solide ou d'objets impliquant l'utilisation de chaleur par convection, c. à d. la chaleur étant transférée d'une source de chaleur au matériau ou aux objets à sécher par un gaz ou par une vapeur, p.ex. l'air le gaz ou la vapeur entraînant le matériau ou les objets à sécher sous forme d'une pulvérisation
B05B 7/10 - Pistolets pulvérisateurs; Appareillages pour l'évacuation produisant une turbulence à la sortie
A nozzle assembly includes a nozzle, a manifold, and wand body. The nozzle, manifold, and wand body can be coupled together to provide a robust spray drying system that can withstand elevated temperature and/or pressure feed stock. In some embodiments, an internal shoulder portion of the manifold can engage with a side of a nozzle collar to restrict distal movement of the nozzle relative to the manifold.
F26B 3/12 - Procédés de séchage d'un matériau solide ou d'objets impliquant l'utilisation de chaleur par convection, c. à d. la chaleur étant transférée d'une source de chaleur au matériau ou aux objets à sécher par un gaz ou par une vapeur, p.ex. l'air le gaz ou la vapeur entraînant le matériau ou les objets à sécher sous forme d'une pulvérisation
B05B 7/10 - Pistolets pulvérisateurs; Appareillages pour l'évacuation produisant une turbulence à la sortie
A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid component including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in a solution with L-carnitine. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building composition can be administered in a monolithic enteric capsule.
A61K 31/202 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique ayant au moins trois doubles liaisons, p.ex. acide linolénique
A61K 31/205 - Sels d'addition d'acides organiques avec des amines; Sels d'ammonium quaternaire internes, p.ex. bétaïne, carnitine
The present disclosure is directed to an oil-in-water emulsion containing at least one hygroscopic ingredient and an edible oil. The emulsion has a water activity of less than about 0.6. The emulsion may be incorporated into an oral dosage form, including a capsule oral dosage form. The ingredients provided in the emulsion are capable of improving the health or well-being of a human or animal.
A61K 47/24 - Composés organiques, p.ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant des atomes autres que des atomes de carbone, d'hydrogène, d'oxygène, d'halogènes, d'azote ou de soufre, p.ex. cyclométhicone ou phospholipides
A61K 47/12 - Acides carboxyliques; Leurs sels ou anhydrides
A61K 47/36 - Polysaccharides; Leurs dérivés, p.ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
A61K 9/48 - Préparations en capsules, p.ex. de gélatine, de chocolat
A23P 10/00 - Mise en forme ou traitement des produits alimentaires caractérisés par les produits
79.
METHOD AND COMPOSITION FOR INCREASING MUSCLE PROTEIN SYNTHESIS
A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid component including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in a solution with L-carnitine. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building composition can be administered in a monolithic enteric capsule.
A61K 31/202 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique ayant au moins trois doubles liaisons, p.ex. acide linolénique
A61K 31/205 - Sels d'addition d'acides organiques avec des amines; Sels d'ammonium quaternaire internes, p.ex. bétaïne, carnitine
80.
METHOD AND COMPOSITION FOR INCREASING MUSCLE PROTEIN SYNTHESIS
A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid derivative including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in an acid resistant capsule delivery form. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building composition can be administered in a monolithic enteric capsule.
A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid derivative including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in an acid resistant capsule delivery form. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building composition can be administered in a monolithic enteric capsule.
Ammonia is used as a processing aid in a method for forming a sprayed solid dispersion comprising an active agent, wherein the active agent, in a free acid form, has a pKa ? 7 and a solubility ? 40 mg/mL in the spray solvent. Ammonia is subsequently removed from the sprayed solid dispersion. Sprayed solid dispersions formed by the disclosed method are also disclosed.
Ammonia is used as a processing aid in a method for forming a sprayed solid dispersion comprising an active agent, wherein the active agent, in a free acid form, has a pKa ≤ 7 and a solubility ≤ 40 mg/mL in the spray solvent. Ammonia is subsequently removed from the sprayed solid dispersion. Sprayed solid dispersions formed by the disclosed method are also disclosed.
Embodiments of a spray-drying process for producing low aspect ratio particles of poly[(methyl methacrylate)-co-(methacrylic acid)] (PMMAMA) are disclosed. In some examples, at least 95% of PMMAMA-containing particles made by the process have an aspect ratio <10. The particles may further include an active ingredient and/or an excipient.
B01J 2/04 - Procédés ou dispositifs pour la granulation de substances, en général; Traitement de matériaux particulaires leur permettant de s'écouler librement, en général, p.ex. en les rendant hydrophobes par division du produit liquide en gouttelettes, p.ex. par pulvérisation, et solidification des gouttelettes en milieu gazeux
Problem to be solved: To provide a whitened or opacified capsule and film without using a white pigment such as titanium dioxide. Solution: A film, a capsule and a film-forming composition characterized by containing a film-forming polymer component selected from gelatin and pullulan and an opacifying agent consisting of a water-soluble salt except calcium salt carbonate and bicarbonate, wherein the salt is selected from a sodium salt, potassium salt, an ammonium salt and a magnesium salt.
Multiparticulate compositions including an active agent and a gelling agent are disclosed. The multiparticulate compositions are prepared by an aqueous-based spray and congeal process.
The instant disclosure provides a capsule composition comprising pullulan, a setting system and a surfactant system that is a sucroglyceride or a sugar fatty acid ester, and methods for making such capsules.
