Abrégé

Methods of treatment and/or prevention of tumours, preferably of solid tumours, more preferably of breast cancer, melanoma, bladder cancer, head and neck cancer, Hodgkin's lymphoma, kidney cancer, non-small cell lung cancer using fermented supernatant, or fractions thereof, of the Lactobacillus casei or paracasei species are disclosed. The species is the strain deposited according to the Budapest Treaty with No. CNCM I-5220 and/or includes in its DNA genome a DNA sequence essentially identical to one of: SEQ ID No 1 to 5.

Classes IPC  ?

• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61P 35/00 - Agents anticancéreux
• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire

Abrégé

The present invention refers to a composition including fermented supernatant of Lactobacillus casei or paracasei species. The species is characterized by having in its DNA genome at least one DNA sequence essentially identical to one of the sequences selected from the group consisting of: SEQ ID NO: 1 to 5, and proper diluents and/or carriers and/or excipients. The composition can be used in the treatment and/or prevention of skin and/or dermatological diseases related to inflammation, allergic reactions, contact hypersensitivity reactions and intolerance, excessive sebaceous secretion, exfoliation or microbial dysbiosis, preferably of the epidermis.

Classes IPC  ?

• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61K 8/99 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de micro-organismes autres que des algues ou des champignons, p. ex. à base de protozoaires ou de bactéries
• A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée
• A61P 17/06 - Antipsoriasiques
• A61P 17/10 - Antiacnéïques
• A61P 17/12 - Kératolytiques, p. ex. préparations pour le traitement des verrues ou des cors

Abrégé

The present invention refers to fermented supernatant, or fractions thereof, of the Lactobacillus casei or paracasei species, said species: - being the strain deposited according to the Budapest Treaty with No. CNCM I-5220 and/or - being characterized by comprising in their DNA genome at least one DNA sequence essentially identical to one of the sequences selected from the group consisting of: SEQ ID No 1 to 5, and for use in the potentiation of an anti-tumour effect of an agent capable of inducing the CD8+ effector cells, said agent preferably being an immune checkpoint inhibitor (ICI) and/or for use in activating tumour immunity and/or for use in a method of treatment and/or prevention of tumours, preferably of solid tumours, more preferably of breast cancer, melanoma, bladder cancer, head and neck cancer, Hodgkin's lymphoma, kidney cancer, non-small cell lung cancer.

Classes IPC  ?

• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61P 35/00 - Agents anticancéreux

Produits et services

Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets; Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes; Fertility enhancement preparations. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Produits et services

Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets; Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Produits et services

Cosmetics; Cosmetics and cosmetic preparations; Functional cosmetics; Non-medicated cosmetics; Cosmetic preparations for skin care; Cosmetics for use on the skin; Cosmetics for personal use; Cosmetic preparations for body care; Cosmetic skin enhancers. Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Food supplements; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes; Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Produits et services

Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Food supplements; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes; Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Produits et services

Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Food supplements; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes; Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Produits et services

Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Food supplements; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes; Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Produits et services

Cosmetics; Cosmetics and cosmetic preparations; Functional cosmetics; Non-medicated cosmetics; Cosmetic preparations for skin care; Cosmetics for use on the skin; Cosmetics for personal use; Cosmetic preparations for body care; Cosmetic skin enhancers. Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Food supplements; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes; Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Produits et services

Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Food supplements; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes; Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Produits et services

Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceuticals; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral dietary supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations; Ferments for pharmaceutical purposes; Milk ferments for pharmaceutical purposes; Ferments for medical or veterinary use; Food supplements; Nutritional supplements; Prebiotic supplements; Medicated food supplements; Food supplements for sportsmen; Food supplements for non-medical purposes; Dietary supplements for animals; Feed supplements for veterinary use; Dietetic foods adapted for medical purposes; Food for medically restricted diets. Milk; Whey; Yoghurt; Yogurt drinks; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Dairy products and dairy substitutes; Milk ferments for culinary purposes; Milk products; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes.

Abrégé

paracasei species in a minimum solution additioned with prebiotic fibers. The fermented supernatant does not have prebiotic fibers.

Classes IPC  ?

• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A23K 10/16 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires
• A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
• A61K 8/60 - SucresLeurs dérivés
• A61K 8/99 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de micro-organismes autres que des algues ou des champignons, p. ex. à base de protozoaires ou de bactéries
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/08 - Solutions
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
• A61P 31/04 - Agents antibactériens
• A61P 37/06 - Immunosuppresseurs, p. ex. médicaments pour le traitement du rejet de greffe
• A61Q 19/00 - Préparations pour les soins de la peau
• C12N 1/20 - BactériesLeurs milieux de culture
• C12R 1/245 - Lactobacillus casei

Abrégé

paracasei species The species is characterized by having in its DNA genome at least one DNA sequence essentially identical to one of the sequences selected from the group consisting of: SEQ ID No 1 to 5, and proper diluents and/or carriers and/or excipients. The compositions can be used in the treatment and/or prevention of skin and/or dermatological diseases related to inflammation, allergic reactions, contact hypersensitivity reactions and intolerance, excessive sebaceous secretion, exfoliation or microbial dysbiosis, preferably of the epidermis.

Classes IPC  ?

• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61K 8/99 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de micro-organismes autres que des algues ou des champignons, p. ex. à base de protozoaires ou de bactéries
• A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée
• A61P 17/06 - Antipsoriasiques
• A61P 17/10 - Antiacnéïques
• A61P 17/12 - Kératolytiques, p. ex. préparations pour le traitement des verrues ou des cors
• C07K 14/335 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Lactobacillus (G)
• C12N 1/02 - Séparation des micro-organismes de leurs milieux de culture

Abrégé

The present invention refers to a composition comprising a fermented supernatant of Lactobacillus casei or paracasei species, said species being characterized by comprising in its DNA genome at least one DNA sequence essentially identical to one of the sequences selected from the group consisting of: SEQ ID No 1 to 5, and proper diluents and/or carriers and/or excipients for use in the treatment and/or prevention of skin and/or dermatological diseases related to inflammation, allergic reactions, contact hypersensitivity reactions and intolerance, excessive sebaceous secretion, exfoliation or microbial dysbiosis), preferably of the epidermis.

Classes IPC  ?

• A61Q 19/08 - Préparations contre le vieillissement
• A61K 8/99 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de micro-organismes autres que des algues ou des champignons, p. ex. à base de protozoaires ou de bactéries
• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• C12R 1/245 - Lactobacillus casei

Abrégé

The present invention refers to a composition comprising: a) a fermented supernatant, or fractions thereof, of Lactobacillus casei or paracasei species, said species being characterized by comprising in their DNA genome at least one DNA sequence essentially identical to one of the sequence selected from the group consisting of: SEQ ID No 1 to 5, and b) proper carriers and/or diluents and/or eccipients, wherein said fermented supernatant is obtainable through a method characterized by the fermentation of said Lactobacillus casei or paracasei species in a minimum solution additioned with prebiotic fibers and wherein said fermented supernatant doesn't comprise prebiotic fibers.

Classes IPC  ?

• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61P 37/00 - Médicaments pour le traitement des troubles immunologiques ou allergiques
• C12R 1/245 - Lactobacillus casei

Produits et services

Chemical and organic compositions for use in the manufacture of food and beverages. Essential oils and aromatic extracts. Dietary supplements for animals; Dietary and nutritional supplements; Dietary supplements for humans not for medical purposes; Fungicides for agricultural use; Herbicide for agricultural use. Agricultural and aquacultural crops, horticulture and forestry products.

Produits et services

Chemical and organic compositions and substances for treatment of leather and textile. Essential oils and aromatic extracts. Sanitary preparations and articles; Collyrium; Disinfectants; Disinfectants for contact lenses; Solutions for contact lenses; Contact lens wetting solutions; Solutions for rinsing contact lenses. Agricultural and aquacultural crops, horticulture and forestry products.

Produits et services

Chemical and organic compositions for use in the manufacture of food and beverages. Dietary supplements for animals; Dietary and nutritional supplements; Dietary supplements for humans not for medical purposes; Fungicides for agricultural use; Herbicide for agricultural use. Agricultural and aquacultural crops, horticulture and forestry products. Advisory services relating to pharmaceuticals; Advice relating to the feeding of animals; Agricultural advice; Information services relating to the use of chemicals used in agriculture.

Produits et services

Bacterial cultures for addition to food products; Lactic cultures for the food industry; Cultures of microorganisms for industrial purposes; Cultures, other than for medical or veterinary use; Blood culture media for scientific use; Media for cell culture for use in the biotechnological industry; Bacteria [other than for medical or veterinary purposes]; Diagnostic kits comprising specimen receptors and reagents for testing for selected bacteria; Chemicals for use in the pharmaceutical industry; Vitamins for use in the manufacture of pharmaceuticals; Antimicrobial preservatives for cosmetics; Emulsifiers for use in the manufacture of cosmetics; Antioxidants for use in the manufacture of cosmetics; Chemical preparations for use in the manufacture of cosmetics; Protein for use in the manufacture of cosmetics; Milk ferments for industrial purposes; Milk ferments for chemical purposes; Lactic acid polymers; Chemical additives for use in the manufacture of cosmetics; Chemical compositions and materials for use in cosmetics; Proteins for use in the manufacture of food supplements; Antimicrobial preservatives for pharmaceuticals; Antioxidants for use in the manufacture of pharmaceuticals. Make-up removing milks; Bath milk; Cleansing milk for toilet purposes; Milky lotions for skin care; Cosmetics; Oils for cosmetic purposes; Tonics [cosmetic]; Cosmetic soaps; Beauty masks; Cosmetic creams; Non-medicated cosmetics; Greases for cosmetic purposes; Beauty care cosmetics; Lotions for cosmetic purposes; Exfoliating scrubs for cosmetic purposes; Serums for cosmetic purposes; Cosmetics in the form of powders; Cosmetic creams and lotions; Cosmetics in the form of gels; Seaweed for cosmetology; Facial preparations; Cosmetic preparations for skin care; Lip protectors [cosmetic]; Cosmetic preparations for body care; Make-up; Cosmetic preparations for use as aids to slimming; Cosmetic preparations for the hair and scalp; Eye gels; Eye lotions; Eyes make-up; Eye compresses for cosmetic purposes. Cultures for medical use; Biological tissue cultures for medical purposes; Collyrium; Eye lotions for medical use; Pharmaceutical preparations; Ocular pharmaceuticals; Pharmaceutical products for ophthalmological use; Pharmaceutical preparations for the prevention of ocular diseases; Dietary and nutritional supplements; Vitamin supplements; Probiotic supplements; Anti-oxidant food supplements; Colostrum supplements; Casein dietary supplements; Mineral food supplements; Mineral dietary supplements for humans; Nutraceuticals for use as a dietary supplement; Herbal dietary supplements for persons special dietary requirements; Probiotic bacterial formulations for medical use; Pharmaceutical compositions; Antibacterial pharmaceuticals; Chemico-pharmaceutical preparations. Milk; Whey; Yogurt; Yogurt drinks; Yoghurt desserts; Preparations for making yoghurt; Drinks made from dairy products; Dairy spreads; Cheese; Cheese substitutes; Cottage cheese; Curd; Acidophilus milk; Smetana [sour cream]; Lactic acid bacteria drinks; Dairy products and dairy substitutes. Custom manufacture of pharmaceuticals; Conversion of targeted substrates into targeted chemical preparations by treatment with enzyme systems; Custom manufacture of biopharmaceuticals. Technical consultancy in relation to research services relating to foods and dietary supplements; Testing of pharmaceuticals; Pharmaceutical research and development; Conducting clinical trials for pharmaceutical products; Conducting early evaluations in the field of new pharmaceuticals; Services for assessing the efficiency of pharmaceuticals; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Providing information about the results of clinical trials for pharmaceutical products; Research relating to biotechnology; Cosmetic research; Research on the subject of pharmaceuticals; Biological research, clinical research and medical research; Research services; Scientific research; Industrial research; Product research and development; Biochemistry research services; Scientific research relating to bacteriology; Medical and pharmacological research services; Biochemical research and analysis; Biotechnological research relating to enzymatic synthesis; Biological research laboratory services; Scientific services and research relating thereto; Research and development services in the field of immunology; Research and development services in the field of bacteriology; Research and development in the field of microorganisms and cells; Information on the subject of scientific research in the field of biochemistry and biotechnology. Providing information about dietary supplements and nutrition; Pharmaceutical services; Dispensing of pharmaceuticals; Provision of pharmaceutical information; Advisory services relating to pharmaceuticals; Medical counseling; Dietetic counselling services [medical]; Advisory services relating to medical services; Consultancy and information services relating to medical products; Consultancy and information services provided via the Internet relating to pharmaceutical products; Consultancy and information services relating to pharmaceutical products.