Provided is a method that prevents decreases in solubility in an organic solvent when elongating a peptide chain by a peptide coupling reaction and improves the reactivity of a peptide chain and the operability in a purification process. The method makes it possible to obtain a polypeptide compound represented by formula (P1) by performing amide formation reaction of the carboxyl group on the right side of the amino acid or the peptide compound in formula (R1) with the amino group on the left side of the amino acid or the peptide ester compound in formula (R2) in which the terminal carboxyl group is protected by a silicon-containing hydrophobic substituent TAG(Si).
Provided is a method that prevents decreases in solubility in an organic solvent when elongating a peptide chain by a peptide coupling reaction and improves the reactivity of a peptide chain and the operability in a purification process. The method makes it possible to obtain a polypeptide compound represented by formula (P1) by performing amide formation reaction of the carboxyl group on the right side of the amino acid or the peptide compound in formula (R1) with the amino group on the left side of the amino acid or the peptide ester compound in formula (R2) in which the terminal carboxyl group is protected by a silicon-containing hydrophobic substituent TAG(Si).
C07K 1/08 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation utilisant des agents d'activation
C07F 7/18 - Composés comportant une ou plusieurs liaisons C—Si ainsi qu'une ou plusieurs liaisons C—O—Si
2.
OBJECT RECOGNITION DEVICE, CONTROL DEVICE, AND OBJECT RECOGNITION METHOD
An object recognition device (10A) is provided with an image acquisition unit (11), an image conversion unit (12), and a recognition unit (13). The image acquisition unit (11) acquires an image obtained by imaging an object. The image conversion unit (12) converts the image into a post-conversion image in which the edge of the object is replaced with the edge having emphasized features. The recognition unit (13) recognizes the object, on the basis of the post-conversion image. The object recognition device (10A) can improve the accuracy of object recognition when recognizing an object from an image obtained by imaging the object.
A power generation system comprises: a muon-catalyzed nuclear fusion device configured to undergo muon-catalyzed nuclear fusion; and a nuclear-reactor power generation device configured such that a nuclear fuel therein is irradiated with neutrons generated as a result of muon-catalyzed nuclear fusion in the muon-catalyzed nuclear fusion device, thereby to carry out power generation, wherein a pressurized-water nuclear reaction vessel in the nuclear-reactor power generation device is arranged so as to surround a nuclear fusion reactor core in which muon-catalyzed nuclear fusion occurs via a structural partition separating the muon-catalyzed nuclear fusion device from the nuclear-reactor power generation device.
A vibration measurement device includes an acceleration sensor, an acceleration sensor mounting fixture, a spacer as an insulating member, and a heat shrink tube. The acceleration sensor includes an element. The acceleration sensor mounting fixture is disposed on a side of the acceleration sensor, adjacent to an object under measurement. The spacer is sandwiched between the acceleration sensor and the acceleration sensor mounting fixture so as to be in contact with both the acceleration sensor and the acceleration sensor mounting fixture. The heat shrink tube covers a sensor outer edge and a mounting fixture outer edge. The heat shrink tube includes a region protruding outward of acceleration sensor and the acceleration sensor mounting fixture as viewed from above.
The present invention provides a method for inexpensively and efficiently synthesizing polypeptide compounds comprising various amino acids. The method involves (i) inducing an amide formation reaction between the carboxyl group on the right side in the formula of the amino acid or peptide compound represented by formula (R1) and the amino group on the left side in the formula of the amino acid ester or peptide ester compound represented by formula (R2) in the presence of an aluminum compound represented by formula (A) to obtain a peptide compound represented by formula (P1) (the definitions of the reference signs in the formula are as presented in the description).
The present invention provides a method for inexpensively and efficiently synthesizing polypeptide compounds comprising various amino acids. The method involves (i) inducing an amide formation reaction between the carboxyl group on the right side in the formula of the amino acid or peptide compound represented by formula (R1) and the amino group on the left side in the formula of the amino acid ester or peptide ester compound represented by formula (R2) in the presence of an aluminum compound represented by formula (A) to obtain a peptide compound represented by formula (P1) (the definitions of the reference signs in the formula are as presented in the description).
C07K 1/08 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation utilisant des agents d'activation
C07K 1/02 - Procédés généraux de préparation de peptides en solution
6.
COMPUTER VISION SYSTEM, COMPUTER VISION METHOD AND COMPUTER VISION PROGRAM
A computer vision system, with at least one processor configured to: acquire, from a sports match video, moving image data of a first period and moving image data of a second period; by using a first machine learning model, generate, based on the moving image data of the first period, first estimation data and second estimation data for an estimation period; by using a second machine learning model, generate, based on the moving image data of the second period, the first estimation data and the second estimation data for the estimation period; and generate determination data based on the first estimation data and the second estimation data that are output from the first machine learning model and the first estimation data and the second estimation data that are output from the second machine learning model.
G06V 20/40 - ScènesÉléments spécifiques à la scène dans le contenu vidéo
G06V 10/70 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique
A computer vision system, with at least one processor configured to: acquire, from a sports match video, a plurality of pieces of consecutive image data indicating a portion of the sports match video, the plurality of pieces of consecutive image data including a plurality of pieces of first consecutive image data that are consecutive; and execute an estimation, by using a machine learning model, of whether the portion is of a predetermined scene type, wherein, in the estimation, the at least one processor is configured to.
G06V 10/771 - Sélection de caractéristiques, p. ex. sélection des caractéristiques représentatives à partir d’un espace multidimensionnel de caractéristiques
G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
G06V 20/40 - ScènesÉléments spécifiques à la scène dans le contenu vidéo
A computer vision system, with at least one processor configured to: acquire, from a sports match video, a plurality of pieces of consecutive image data indicating a portion of the sports match video, the plurality of pieces of consecutive image data including a plurality of pieces of first consecutive image data that are consecutive and a plurality of pieces of second consecutive image data that are consecutive after the plurality of pieces of first consecutive image data; and execute an estimation, by using a machine learning model, of whether the portion is of a predetermined scene type.
G06V 10/771 - Sélection de caractéristiques, p. ex. sélection des caractéristiques représentatives à partir d’un espace multidimensionnel de caractéristiques
G06V 20/40 - ScènesÉléments spécifiques à la scène dans le contenu vidéo
9.
METHOD FOR PRODUCING PEPTIDE COMPOUNDS USING NOVEL SILYL TAG
Provided is a method that, in peptide chain elongation by a peptide coupling reaction, prevents decreases in the solubility in organic solvents and improves the reactivity of the peptide chain and the operability in the purification process. The method yields a polypeptide compound by carrying out an amide formation reaction between the carboxyl group on the right side of the formula of an amino acid or peptide compound having formula (R1), and the amino group on the left side of the formula of an amino acid ester or peptide ester compound having formula (R2) in which the terminal carboxyl group is protected by a silicon-containing hydrophobic substituent TAG(Si). (The reference symbols in the formulas are defined as described in the claims.)
The present invention provides a novel means capable of producing an amide compound by highly stereoselectively and/or highly efficiently causing an amide reaction in various substrates having a carboxyl group and an amino group. This reaction agent causes an amide reaction between a carboxyl group and an amino group, and contains a silane compound represented by general formula (C1) or the like.
The present invention provides a novel means capable of producing an amide compound by highly stereoselectively and/or highly efficiently causing an amide reaction in various substrates having a carboxyl group and an amino group. This reaction agent causes an amide reaction between a carboxyl group and an amino group, and contains a silane compound represented by general formula (C1) or the like.
The present invention provides a novel means capable of producing an amide compound by highly stereoselectively and/or highly efficiently causing an amide reaction in various substrates having a carboxyl group and an amino group. This reaction agent causes an amide reaction between a carboxyl group and an amino group, and contains a silane compound represented by general formula (C1) or the like.
(In general formula (C1), each substituent is as defined in the claims)
C07K 1/00 - Procédés généraux de préparation de peptides
C07C 231/02 - Préparation d'amides d'acides carboxyliques à partir d'acides carboxyliques ou à partir de leurs esters, anhydrides ou halogénures par réaction avec de l'ammoniac ou des amines
C07D 307/54 - Radicaux substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
C07K 1/10 - Procédés généraux de préparation de peptides utilisant des agents de couplage
11.
SILANE-CONTAINING CONDENSED CYCLIC DIPEPTIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND METHOD FOR PRODUCING POLYPEPTIDE COMPOUND USING SAME
The present invention provides, as a novel compound that can be utilized for efficient synthesis or the like of a polypeptide comprising various amino acids, a silane-containing condensed cyclic dipeptide compound represented by formula (A).
The present invention provides, as a novel compound that can be utilized for efficient synthesis or the like of a polypeptide comprising various amino acids, a silane-containing condensed cyclic dipeptide compound represented by formula (A).
The present invention provides, as a novel compound that can be utilized for efficient synthesis or the like of a polypeptide comprising various amino acids, a silane-containing condensed cyclic dipeptide compound represented by formula (A).
In formula (A), each of R11, R12, R13, R21, and R22 independently represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxyl group, a nitro group, a cyano group, or a thiol group, or a monovalent aliphatic hydrocarbon group, aromatic hydrocarbon group, or heterocyclic group that may have one or more substituents; and each of Ra1 and Ra2 independently represents a monovalent aliphatic hydrocarbon group or aromatic hydrocarbon group that may have one or more substituents
A method of producing a polypeptide compound, wherein a peptide compound represented by formula (P) is obtained by inducing an amide formation reaction between an amino-protected lactam compound represented by formula (R1) and an amino acid ester or peptide ester compound represented by formula (R2).
A method of producing a polypeptide compound, wherein a peptide compound represented by formula (P) is obtained by inducing an amide formation reaction between an amino-protected lactam compound represented by formula (R1) and an amino acid ester or peptide ester compound represented by formula (R2).
A method of producing a polypeptide compound, wherein a peptide compound represented by formula (P) is obtained by inducing an amide formation reaction between an amino-protected lactam compound represented by formula (R1) and an amino acid ester or peptide ester compound represented by formula (R2).
The definitions for the reference signs in formulae (R1), (R2), and (P) are as set forth in the claims.
Provided are: a novel diketopiperazine compound for rapid and easy synthesis of various polypeptides; and a method for manufacturing the same. The diketopiperazine compound is represented by general formula (1). (In the formula, R1, R2, R3, R4, and R5are each independently a hydrogen atom, a substituted or unsubstituted hydrocarbon group, or a substituted or unsubstituted heterocyclic group. R1and R2, R1and R5, R2and R5, and/or R3and R4 are each optionally bonded to form a ring. PGE represents an electron-withdrawing protective group.)
C07D 241/08 - Composés hétérocycliques contenant des cycles diazine-1,4 ou diazine-1,4 hydrogéné non condensés avec d'autres cycles comportant une ou deux liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des atomes d'oxygène liés directement aux atomes de carbone du cycle
C07K 1/00 - Procédés généraux de préparation de peptides
A nuclear fusion system comprises: a muon generation unit to generate negative muons including electron and positron accelerators for generating electron and positron beams; a gas supply unit to supply to circulate gaseous deuterium or gaseous deuterium-tritium mixture as raw material gas; a Laval nozzle to accelerate the raw material gas to supersonic velocity; and a shock wave cone connected to the Laval nozzle to introduce the raw material gas accelerated to supersonic velocity to generate an oblique shock wave, the raw material gas accelerated to supersonic velocity being introduced into the shock wave cone to generate the oblique shock wave, the oblique shock wave being decelerated to create a high-density gas target in an in-flight manner, the muons generated as a result of causing electrons and positrons to collide with each other being introduced into the high-density gas target thereby to cause a muon-catalyzed nuclear fusion reaction to occur.
A learning model generates a plurality of prototype vectors and generates an integrated similarity vector that indicates similarity between an input image and each prototype for a plurality of prototypes in accordance with similarity between one prototype vector and each pixel vector in a feature map acquired from an CNN. An image processing apparatus obtains prototype belongingness (distributed prototype belongingness) for each image by distributing prototype belongingness of a belonged prototype of each class to each of two or more images that belong to one class. Then, the learning model is subjected to machine learning in accordance with the distributed prototype belongingness of each prototype vector for each image so that each prototype vector is brought closer to any pixel vector in the feature map corresponding to each image.
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 10/74 - Appariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
G06V 10/776 - ValidationÉvaluation des performances
16.
COMPUTER VISION SYSTEM, COMPUTER VISION METHOD, AND COMPUTER VISION PROGRAM
A video data acquisition unit (31) acquires video data (VC1) of a first period and video data (VC2) of a second period from video of a sporting contest. A first machine learning model (32a) generates, on the basis of the video data (VC1) of the first period, first estimation data (ED1-1) and second estimation data (ED2-1) for a period (TP) to be estimated. A second machine learning model (32b) generates, on the basis of the video data (VC2) of the second period, first estimation data (ED1-2) and second estimation data (ED2-2) for the period (TP) to be estimated. On the basis of the first estimation data (ED1-1), the second estimation data (ED2-1), the first estimation data (ED1-2), and the second estimation data (ED2-2), a determination data generation unit (33) generates determination data (DD) regarding the period (TP) to be estimated.
Provided is a method for producing a silane-containing condensed ring dipeptide compound represented by formula (A). The method comprises: (i) a step for reacting a first amino acid represented by formula (R1) with a first silane compound represented by formula (S1); (ii) a step for reacting a second amino acid represented by formula (R2) with a second silane compound represented by formula (S2); and (iii) a step for mixing and further reacting the reaction product in step (i) with the reaction product in step (ii) to obtain the condensed ring dipeptide compound represented by formula (A). (The definitions of the respective substituents in the formulae are as described in the claims.)
This method comprises: (i) a step for forming an amide bond between a Ta-substituted carboxyl group located on the right side in formula (R1) in an N-terminal-protected amino acid or peptide ester represented by formula (R1) and an amino group amino group located on the left side in formula (R2) in an amino acid or peptide represented by formula (R2) or an ester compound thereof to produce an N-terminal-protected peptide represented by formula (S1); (ii) a step for deprotecting the N-terminal of the compound represented by formula (S1) produced in step (i) to produce a peptide compound represented by formula (P1); and (iii) a step for repeatedly performing the steps (i) and (ii) using the compound represented by formula (P1) produced in step (ii) as the compound represented by formula (R2) in step (i) to extend a peptide chain by amidation. In formulae (R1), (R2), (S1) and (P1), each symbol is as defined in the claims.
Provided is a computer vision system having a machine learning model that estimates a scene type associated with an arbitrary portion of a sports game video and that is not prone to gradient vanishing during learning. A computer vision system (10) has a consecutive image data acquisition unit and a machine learning model (M), wherein the machine learning model (M) comprises: a first-half image feature quantity acquisition unit (411) that acquires a plurality of first-half image feature quantities (F1) from a plurality of first-half consecutive image data (CD1); a saliency-weighted first-half feature quantity acquisition unit (421) that acquires a plurality of saliency-weighted first-half feature quantities (F2) from the plurality of first-half image feature quantities F1; and an estimation result acquisition unit (50) that acquires an estimation result on the basis of the plurality of saliency-weighted first-half feature quantities (F2).
Provided is a technology with which the basis for image similarity can be explained on a conceptual basis. In this image processing device, a plurality of feature vectors (in a feature space) are acquired, said feature vectors being outputted from a trained model in response to the input of a plurality of input images to the trained model, and said trained model resulting from performing machine learning (step S21). A hierarchical plurality of clusters is generated by subjecting the plurality of feature vectors to hierarchical clustering processing (step S22). A partial space or vector corresponding to a specific cluster among the plurality of clusters is then extracted as a concept (concept expression) of the specific cluster (step S23).
[Problem] To provide a power generation method and a power generation system that utilize water radiolysis. [Solution] A power generation method for generating power through water radiolysis, the power generation method comprising: a step for preparing a power generation tank that is capable of containing water and has a pair of electrodes disposed therein, and dispersing metal oxide particles having oxygen non-stoichiometry and conductivity in the water; a step for irradiating the water containing the metal oxide particles dispersed therein with radiation from a radiation source; a step for locally depositing the metal oxide particles in the vicinity of one of the electrodes after the radiation irradiation; and a step for extracting electricity from the electrodes.
[Problem] To provide a "power generation system and power generation method" based on a new atomic reactor resulting from a combination of a means for regularly generating muon catalyzed nuclear fusion and an atomic reactor having a thorium decay series as fuel. [Solution] A power generation S system comprising a muon catalyzed nuclear fusion system S1 and an atomic reactor power generation system S2. The muon catalyzed nuclear fusion system S1 is integrally formed such that transportation between a nuclear fusion reactor structure S1 of the muon catalyzed nuclear fusion system S1 and an atomic reactor structure of the atomic reactor power generation system S2 are separated by a structural barrier wall 20, which is a pipe wall of a gas flow path, and such that nuclear fusion neutrons pass through the structural barrier wall 20 and irradiate the atomic reactor power generation system S2 from the muon catalyzed nuclear fusion system S1.
G21G 1/02 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p. ex. production d'isotopes radioactifs dans les réacteurs nucléaires
G21B 3/00 - Réacteurs de fusion nucléaire à basse température, p. ex. réacteurs de fusion dite froide
Disclosed is a method with which it is possible to observe a biological sample in a living state, without significant restrictions due to the properties of the sample or due to a structural body accommodating the sample. To observe a target sample on a sample stage using a SEM including a radiation source for electron beam irradiation, the method includes:
a step of bringing an insulating and electron-permeable thin film into contact with the target sample in such a way as to follow a surface on the radiation source side of the target sample, and sealing the target sample in a gap between the film and the sample stage; and
a step of radiating an electron beam onto the target sample from the radiation source through the film.
Provided is a method that prevents decreases in solubility in an organic solvent when elongating a peptide chain by a peptide coupling reaction and improves the reactivity of a peptide chain and the operability in a purification process. The method makes it possible to obtain a polypeptide compound represented by formula (P1) by performing amide formation reaction of the carboxyl group on the right side of the amino acid or the peptide compound in formula (R1) with the amino group on the left side of the amino acid or the peptide ester compound in formula (R2) in which the terminal carboxyl group is protected by a silicon-containing hydrophobic substituent TAG(Si).
The present invention provides a catalyst containing a Brønsted acid as a novel means capable of producing an amide compound by highly stereoselectively and/or highly efficiently causing an amidation reaction in a variety of substrates having a carboxylic ester group and an amino group.
C07K 1/10 - Procédés généraux de préparation de peptides utilisant des agents de couplage
B01J 31/04 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des acides carboxyliques ou leurs sels
B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
C07K 1/06 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation
Provided is a computer vision system having a machine learning model for estimating the classification of a scenario pertaining to one discretionary portion of a sports match video, the machine learning model being such that gradient loss does not readily occur during learning. This computer vision system (10) has a continuous image data acquisition unit and a machine learning model (M), the machine learning model (M) having a first-half image feature quantity acquisition unit (411) for acquiring a plurality of first-half image feature quantities (F1), a second-half image feature quantity acquisition unit (412) for acquiring a plurality of second-half image feature quantities (F2), a sequence-information-equipped first-half feature quantity acquisition unit (421) for acquiring a plurality of sequence-information-equipped first-half feature quantities (F3), a sequence-information-equipped second-half feature quantity acquisition unit (422) for acquiring a plurality of sequence-information-equipped second-half feature quantities (F4), a relatedness-information-equipped first-half feature quantity acquisition unit (431) for acquiring a plurality of relatedness-information-equipped first-half feature quantities (F5), a relatedness-information-equipped second-half feature quantity acquisition unit (432) for acquiring a plurality of relatedness-information-equipped second-half feature quantities (F6), and an estimation result acquisition unit (50) for acquiring a result of estimation on the basis of the plurality of relatedness-information-equipped first-half feature quantities (F5) and the plurality of relatedness-information-equipped second-half feature quantities (F6).
A vibration measurement device (100) comprises an acceleration sensor and acceleration sensor attachment tool and is capable of suppressing discharging accompanying high voltage surges caused by lightning strikes and preventing acceleration sensor failure. The vibration measurement device (100) comprises the acceleration sensor (10), the acceleration sensor attachment tool (21), a spacer (32) serving as an insulating member, and a heat shrink tube (31). The acceleration sensor (10) comprises an element (11). The acceleration sensor attachment tool (21) is disposed on the same side of the acceleration sensor (10) as an object (1) under measurement. The spacer (32) is sandwiched between the acceleration sensor (10) and the acceleration sensor attachment tool (21) so as to touch the acceleration sensor (10) and the acceleration sensor attachment tool (21). The heat shrink tube (31) covers the sensor outer edge (10a) and the attachment tool outer edge (21a). The heat shrink tube (31) comprises a region that protrudes to the outside of the acceleration sensor (10) and acceleration sensor attachment tool (21) in plan view.
G01H 1/00 - Mesure des vibrations dans des solides en utilisant la conduction directe au détecteur
G01H 17/00 - Mesure des vibrations mécaniques ou des ondes ultrasonores, sonores ou infrasonores non prévue dans les autres groupes de la présente sous-classe
G01M 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
F03D 17/00 - Surveillance ou test de mécanismes moteurs à vent, p. ex. diagnostics
[Problem] To provide a novel means capable of generating highly stereoselective and/or highly efficient amidation reactions in a variety of substrates having a carboxyl group and an amino group, and capable of producing amide compounds.
[Problem] To provide a novel means capable of generating highly stereoselective and/or highly efficient amidation reactions in a variety of substrates having a carboxyl group and an amino group, and capable of producing amide compounds.
[Solution] A reaction agent for amide reactions between carboxyl groups and amino groups and including a silane compound indicated by general formula (A) and/or general formula (B).
[Problem] To provide a novel means capable of generating highly stereoselective and/or highly efficient amidation reactions in a variety of substrates having a carboxyl group and an amino group, and capable of producing amide compounds.
[Solution] A reaction agent for amide reactions between carboxyl groups and amino groups and including a silane compound indicated by general formula (A) and/or general formula (B).
[Problem] To provide a novel means capable of generating highly stereoselective and/or highly efficient amidation reactions in a variety of substrates having a carboxyl group and an amino group, and capable of producing amide compounds.
[Solution] A reaction agent for amide reactions between carboxyl groups and amino groups and including a silane compound indicated by general formula (A) and/or general formula (B).
(In general formulas (A) and (B), each substituent represents the definition described in the Claims.)
C07F 7/10 - Composés comportant une ou plusieurs liaisons C—Si azotés
C07C 231/02 - Préparation d'amides d'acides carboxyliques à partir d'acides carboxyliques ou à partir de leurs esters, anhydrides ou halogénures par réaction avec de l'ammoniac ou des amines
C07D 223/12 - Atomes d'azote ne faisant pas partie d'un radical nitro
B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
C07K 1/08 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation utilisant des agents d'activation
A method of producing a polypeptide compound, wherein a peptide compound represented by formula (P) is obtained by inducing an amide formation reaction between an amino-protected lactam compound represented by formula (R1) and an amino acid ester or peptide ester compound represented by formula (R2). The definitions for the reference signs in formulae (R1), (R2), and (P) are as set forth in the claims.
The present invention provides a method for inexpensively and efficiently synthesizing polypeptide compounds comprising various amino acids. The method involves (i) inducing an amide formation reaction between the carboxyl group on the right side in the formula of the amino acid or peptide compound represented by formula (R1) and the amino group on the left side in the formula of the amino acid ester or peptide ester compound represented by formula (R2) in the presence of an aluminum compound represented by formula (A) to obtain a peptide compound represented by formula (P1) (the definitions of the reference signs in the formula are as presented in the description).
C07K 1/08 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation utilisant des agents d'activation
[Problem] To be able to automatically detect lightning using a plurality of cameras and computers, and to specify a blade struck by the lightning, reduce the area on the blade on which lightning can strike, and detect the state of damage of points struck by lightning. [Solution] A lightning detection system for detecting damage caused by lightning to a wind power generation facility according to the present invention includes: a lightning detection imaging device that detects lightning while capturing images of a wind turbine having a rotating blade; and a lightning detection means that detects lightning on the basis of the result of comparing the sum of the absolute difference values of each of pixels between successive frames and a preset difference value detection threshold on the basis of image signals from the lightning detection imaging device.
[Problem] An objective of the present invention is to provide a nuclear fusion system and a nuclear fusion method that allow efficient muon capture in a gas target with a smaller device. Another objective of the present invention is to also provide a nuclide transmutation life-shortening treatment system for a long-lived fission product and a nuclide transmutation life-shortening treatment method for a long-lived fission product that make it possible to perform nuclide transmutation by efficiently irradiating an LLFP with neutrons produced by the nuclear fusion system and the nuclear fusion method. [Solution] A nuclear fusion system (S) comprises: a muon production means (1) for producing muons; a gas supply means (2) for supplying and circulating raw material gas; a Laval nozzle (3) for accelerating the raw material gas to a supersonic speed; and a shock cone (4). The raw material gas accelerated to a supersonic speed by the Laval nozzle (3) is introduced into the shock cone (4) to generate an oblique shock wave. The oblique shock wave is decelerated to form a high-density gas target in the air. Muons are produced by the muon production means (1) through collision between electrons and positrons, and are introduced into the thus formed high-density gas target to cause a nuclear fusion reaction.
G21G 1/10 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p. ex. production d'isotopes radioactifs à l'extérieur des réacteurs nucléaires ou des accélérateurs de particules par bombardement avec des particules électriquement chargées
G21F 9/00 - Traitement des matériaux contaminés par la radioactivitéDispositions à cet effet pour la décontamination
G21B 3/00 - Réacteurs de fusion nucléaire à basse température, p. ex. réacteurs de fusion dite froide
33.
SILANE-CONTAINING CONDENSED CYCLIC DIPEPTIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND METHOD FOR PRODUCING POLYPEPTIDE COMPOUND USING SAME
The present invention provides, as a novel compound that can be utilized for efficient synthesis or the like of a polypeptide comprising various amino acids, a silane-containing condensed cyclic dipeptide compound represented by formula (A). In formula (A), each of R11, R12, R13, R21, and R22independently represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxyl group, a nitro group, a cyano group, or a thiol group, or a monovalent aliphatic hydrocarbon group, aromatic hydrocarbon group, or heterocyclic group that may have one or more substituents; and each of Ra1and Ra2 independently represents a monovalent aliphatic hydrocarbon group or aromatic hydrocarbon group that may have one or more substituents.
C07F 7/18 - Composés comportant une ou plusieurs liaisons C—Si ainsi qu'une ou plusieurs liaisons C—O—Si
C07C 269/04 - Préparation de dérivés d'acide carbamique, c.-à-d. de composés contenant l'un des groupes l'atome d'azote ne faisant pas partie de groupes nitro ou nitroso à partir d'amines avec formation de groupes carbamate
C07C 271/22 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec les atomes d'azote des groupes carbamate liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes de carbone de radicaux hydrocarbonés substitués par des groupes carboxyle
C07C 319/20 - Préparation de thiols, de sulfures, d'hydropolysulfures ou de polysulfures de sulfures par des réactions n'impliquant pas la formation de groupes sulfure
C07C 323/51 - Thiols, sulfures, hydropolysulfures ou polysulfures substitués par des halogènes, des atomes d'oxygène ou d'azote ou par des atomes de soufre ne faisant pas partie de groupes thio contenant des groupes thio et des groupes carboxyle liés au même squelette carboné ayant les atomes de soufre des groupes thio liés à des atomes de carbone acycliques du squelette carboné
C07C 323/57 - Thiols, sulfures, hydropolysulfures ou polysulfures substitués par des halogènes, des atomes d'oxygène ou d'azote ou par des atomes de soufre ne faisant pas partie de groupes thio contenant des groupes thio et des groupes carboxyle liés au même squelette carboné ayant les atomes de soufre des groupes thio liés à des atomes de carbone acycliques du squelette carboné le squelette carboné étant substitué de plus par des atomes d'azote, ne faisant pas partie de groupes nitro ou nitroso
C07K 1/06 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation
C07K 1/10 - Procédés généraux de préparation de peptides utilisant des agents de couplage
NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION RESEARCH SYSTEM (Japon)
CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (Japon)
Inventeur(s)
Abe, Madoka
Kondo, Satoshi
Shimada, Takehiko
Hanada, Kosuke
Mochida, Keiko
Tsuge, Takashi
Abrégé
Antimicrobial activity exhibited against a wide variety of plant pathogens. A functional peptide consisting of the amino acid sequence: YYGFPAFSERTRKFWRIWKGKTS (SEQ ID NO: 1) or an amino acid sequence having an identity of 85% or more with respect to the amino acid sequence, or consisting of a partial peptide thereof.
NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (Japon)
CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (Japon)
Inventeur(s)
Abe, Madoka
Kondo, Satoshi
Shimada, Takehiko
Hanada, Kosuke
Mochida, Keiko
Tsuge, Takashi
Abrégé
Antimicrobial activity exhibited against a wide variety of plant pathogens. A functional peptide consisting of the amino acid sequence: MKVMIVVKTKVKNKKVAKMMVK (SEQ ID NO: 1) or an amino acid sequence having an identity of 85% or more with respect to the amino acid sequence, or consisting of a partial peptide thereof.
The present invention provides a device for trapping a specific substance in a sample liquid. The device includes a filter member through which the sample liquid can pass. The filter member is formed from an organic polymer and has, on an external surface thereof, a first region and a second region. The first region is a region that serves as an entrance for introducing the sample liquid into the filter member. The second region is a region that serves as an exit for the sample liquid to exit to the outside after passing through the filter member. A trapping substance for trapping the specific substance is not joined to the first region, but is joined to the second region.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
37.
OBSERVATION METHOD EMPLOYING SCANNING ELECTRON MICROSCOPE, AND SAMPLE HOLDER FOR SAME
The present invention provides a method with which it is possible to observe a biological sample in a living state, without significant restrictions due to the properties of the sample itself or due to a structural body accommodating the sample. This method for observing a target sample on a sample stage using a scanning electron microscope which includes a radiation source for electron beam irradiation is characterized by including: a step of bringing an insulating and electron-permeable thin film into contact with the target sample in such a way as to follow the surface of the target sample on the radiation source side thereof, and sealing the target sample in a gap between the thin film and the sample stage; and a step of radiating the electron beam onto the target sample from the radiation source through the thin film.
A network model 20 is provided with a plurality of units 30 which execute mutually different recognition processing with respect to an input image 40. Each unit 30 is provided with an attention portion 31 and a recognition portion 33. The attention portion 31 outputs an attention map 42 indicating the distribution, on the input image 40, of a degree of attention, being the degree to which attention is paid. The recognition portion 33 outputs a recognition result with respect to the input image 40 on the basis of the attention map 42 and a feature map 41 indicating a feature extracted from the input image 40. The attention portion 31 of any unit 30 is trained by means of a correct answer attention map generated in accordance with an instruction from a person who has recognized the input image 40.
[Problem] To provide: a method for producing a carbon-dioxide-adsorbed sintered body, in which carbon dioxide is not generated during the production and carbon dioxide in a combustion exhaust gas can be reduced; and a carbon-dioxide-adsorbed sintered body which is produced by the method. [Solution] The method comprises: an ignition loss amount adjusting step for adjusting the ignition loss amount of a coal ash; a Ca source adjusting step for adjusting the mixing amount of a Ca source (a concrete powder, an iron steel slag) to be mixed with the coal ash; a mixing step for mixing the coal ash of which the ignition loss amount has been adjusted in the ignition loss amount adjusting step with the calcium source of which the mixing amount has been adjusted in the calcium source adjusting step; a temperature rising step for irradiating a mixture that has been mixed in the mixing step with microwaves to rise the temperature of the mixture to a temperature equal to or higher than a sintering temperature, thereby sintering the mixture; and a temperature lowering step for blowing a combustion exhaust gas into a sintered body of the mixture which has been obtained in the temperature rising step during the process for lowering the temperature of the sintered body.
The present invention provides a catalyst containing a Brønsted acid as a novel means capable of producing an amide compound by highly stereoselectively and/or highly efficiently causing an amidation reaction in a variety of substrates having a carboxylic ester group and an amino group.
B01J 31/04 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des acides carboxyliques ou leurs sels
B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
B01J 31/12 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des composés organométalliques ou des hydrures métalliques
B01J 31/14 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des composés organométalliques ou des hydrures métalliques d'aluminium ou de bore
C07C 269/06 - Préparation de dérivés d'acide carbamique, c.-à-d. de composés contenant l'un des groupes l'atome d'azote ne faisant pas partie de groupes nitro ou nitroso par des réactions n'impliquant pas la formation de groupes carbamate
C07C 271/18 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec les atomes d'azote des groupes carbamate liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes de carbone de radicaux hydrocarbonés substitués par des atomes d'oxygène liés par des liaisons doubles
C07C 319/20 - Préparation de thiols, de sulfures, d'hydropolysulfures ou de polysulfures de sulfures par des réactions n'impliquant pas la formation de groupes sulfure
C07C 323/41 - Y étant un atome d'hydrogène ou de carbone acyclique
C07K 1/00 - Procédés généraux de préparation de peptides
Provided is a novel method whereby an amide compound can be produced by highly stereoselectively and efficiently performing amidation between a plurality of amino acids and/or peptides. A compound of general formula (3) is synthesized by forming an amide bond between the carboxyl group on the right side of general formula (1) in a compound represented thereby and the amino group on the left side of general formula (2) in a compound represented thereby, in the presence of a Lewis acid catalyst and a silylating agent [in formulae (1), (2) and (3), each symbol has the same meaning as defined in claims].
C07K 1/08 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation utilisant des agents d'activation
C07K 1/00 - Procédés généraux de préparation de peptides
C07C 231/02 - Préparation d'amides d'acides carboxyliques à partir d'acides carboxyliques ou à partir de leurs esters, anhydrides ou halogénures par réaction avec de l'ammoniac ou des amines
C07K 1/02 - Procédés généraux de préparation de peptides en solution
42.
REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME
[Problem] To provide a novel means capable of generating highly stereoselective and/or highly efficient amidation reactions in a variety of substrates having a carboxyl group and an amino group, and capable of producing amide compounds. [Solution] A reaction agent for amide reactions between carboxyl groups and amino groups and including a silane compound indicated by general formula (A) and/or general formula (B). (In general formulas (A) and (B), each substituent represents the definition described in the Claims.)
C07C 231/02 - Préparation d'amides d'acides carboxyliques à partir d'acides carboxyliques ou à partir de leurs esters, anhydrides ou halogénures par réaction avec de l'ammoniac ou des amines
C07C 233/05 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués avec des atomes de carbone de groupes carboxamide liés à des atomes de carbone d'un squelette carboné saturé acyclique ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques
C07C 233/18 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un radical hydrocarboné substitué par des atomes d'oxygène liés par des liaisons simples avec le radical hydrocarboné substitué lié à l'atome d'azote du groupe carboxamide par un atome de carbone acyclique ayant l'atome de carbone du groupe carboxamide lié à un atome d'hydrogène ou à un atome de carbone d'un squelette carboné acyclique saturé
C07D 223/12 - Atomes d'azote ne faisant pas partie d'un radical nitro
C07F 7/10 - Composés comportant une ou plusieurs liaisons C—Si azotés
C07K 1/08 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation utilisant des agents d'activation
43.
REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME
The present invention provides a novel means capable of producing an amide compound by highly stereoselectively and/or highly efficiently causing an amide reaction in various substrates having a carboxyl group and an amino group. This reaction agent causes an amide reaction between a carboxyl group and an amino group, and contains a silane compound represented by general formula (C1) or the like. (In general formula (C1), each substituent is as defined in the claims)
C07C 233/08 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués avec des atomes de carbone de groupes carboxamide liés à des atomes de carbone acycliques d'un squelette carboné saturé contenant des cycles
C07C 233/58 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone de cycles autres que des cycles aromatiques à six chaînons ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués
C07C 233/65 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone de cycles aromatiques à six chaînons ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués
C07D 307/54 - Radicaux substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
44.
Superconducting cable and installation method of the same
When bending a superconducting cable of a stack conductor structure in which a plurality of layers of tape wires are stacked, a twisting process is performed for the superconducting cable immediately before a bending portion of the superconducting cable.
H01B 12/00 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs
H01B 12/08 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par leurs formes à fils toronnés ou tressés
H01B 12/16 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par le refroidissement
H01R 4/68 - Connexions à ou entre conducteurs supraconducteurs
H02G 1/14 - Méthodes ou appareils spécialement adaptés à l'installation, entretien, réparation, ou démontage des câbles ou lignes électriques pour la jonction ou la terminaison de câbles
45.
Iodine-loaded bone repair material and method for producing the same
A highly safe and inexpensive bone repair material that stably exhibits high antibacterial activity for a long time in a living body by supporting a large amount of an iodine ion and is excellent in apatite forming ability and preservability. The material includes a substrate made of titanium or titanium alloy and a titanate film on a surface of the substrate, the film composed of a large number of crystalline masses having a crystal structure and containing a calcium ion and an iodine ion, wherein the mass contains layers having a Ti—O skeleton and the calcium and the iodine ions adsorbed between the layers.
A nuclear fusion system includes: a muon generation unit for generating negative muons; a gas supply unit for circulating and supplying gaseous deuterium or gaseous deuterium-tritium mixture as raw material gas for a nuclear fusion reaction; and a Laval nozzle for accelerating the raw material gas to supersonic velocity including a flow regulation portion in which the muons are decelerated and a reaction portion in which the nuclear fusion reaction occurs, wherein an oblique shockwave, which is generated as a result of collision of a shock wave generator arranged inside the reaction portion and the raw material gas accelerated to supersonic velocity, converges on a center axis of the Laval nozzle, and thereby a high-density gas target is retained in a gas phase, and wherein the muons are introduced into the high-density gas target, and thereby the nuclear fusion reaction is caused to occur.
xyz444. A microwave absorbing body and a microwave heating body according to the present invention are configured of this microwave absorbing composition. Preferably, this microwave absorbing body and this microwave heating body are powders, molded bodies or sintered bodies. A microwave heating device is configured so as to comprise this microwave heating body.
C04B 35/56 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base de non oxydes à base de carbures
NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (Japon)
CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (Japon)
Inventeur(s)
Abe Madoka
Kondo Satoshi
Shimada Takehiko
Hanada Kosuke
Mochida Keiko
Tsuge Takashi
Abrégé
Antimicrobial activity exhibited against a wide variety of plant pathogens. A functional peptide consisting of the amino acid sequence: MKVMIVVKTKVKNKKVAKMMVK (SEQ ID NO: 1) or an amino acid sequence having an identity of 85% or more with respect to the amino acid sequence, or consisting of a partial peptide thereof.
NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (Japon)
CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (Japon)
Inventeur(s)
Abe Madoka
Kondo Satoshi
Shimada Takehiko
Hanada Kosuke
Mochida Keiko
Tsuge Takashi
Abrégé
Antimicrobial activity exhibited against a wide variety of plant pathogens. A functional peptide consisting of the amino acid sequence: YYGFPAFSERTRKFWRIWKGKTS (SEQ ID NO: 1) or an amino acid sequence having an identity of 85% or more with respect to the amino acid sequence, or consisting of a partial peptide thereof.
Provided is a novel method for producing amide compounds at high stereochemical selectivities. The method according to the present invention for producing amide compounds is provided with an amidation step for reacting, in the presence of a catalyst comprising a metal compound, an amino compound with an aminoester compound represented by general formula (1) to amidate the ester group in the aminoester compound.
C07C 231/02 - Préparation d'amides d'acides carboxyliques à partir d'acides carboxyliques ou à partir de leurs esters, anhydrides ou halogénures par réaction avec de l'ammoniac ou des amines
C07C 231/12 - Préparation d'amides d'acides carboxyliques par des réactions n'impliquant pas la formation de groupes carboxamide
C07C 269/06 - Préparation de dérivés d'acide carbamique, c.-à-d. de composés contenant l'un des groupes l'atome d'azote ne faisant pas partie de groupes nitro ou nitroso par des réactions n'impliquant pas la formation de groupes carbamate
B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
B01J 31/36 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant en outre des composés métalliques inorganiques non prévus dans les groupes du vanadium, du niobium ou du tantale
C07C 237/12 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des groupes amino ayant les atomes de carbone des groupes carboxamide liés à des atomes de carbone acycliques du squelette carboné le squelette carboné étant acyclique et saturé ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone acyclique d'un radical hydrocarboné substitué par des groupes carboxyle
C07C 271/20 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec les atomes d'azote des groupes carbamate liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes de carbone de radicaux hydrocarbonés substitués par des atomes d'azote ne faisant pas partie de groupes nitro ou nitroso
C07C 271/22 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec les atomes d'azote des groupes carbamate liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes de carbone de radicaux hydrocarbonés substitués par des groupes carboxyle
51.
BONE REPAIR IMPLANT AND METHOD FOR MANUFACTURING SAME
EDUCATIONAL FOUNDATION OF OSAKA MEDICAL AND PHARMACEUTICAL UNIVERSITY (Japon)
CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (Japon)
OSAKA YAKIN KOGYO CO., LTD. (Japon)
Inventeur(s)
Ueno Takaaki
Nakajima Yoichiro
Yamaguchi Seiji
Matsushita Tomiharu
Kitagaki Hisashi
Mori Shigeo
Abrégé
The bone repair implant 10 according to the present invention is a bone repair implant, comprising titanium or a titanium alloy, for being installed at a bone injury site A of a patient, wherein the implant is characterized by: comprising a plate-shaped part 11 at least partially having a surface morphology that corresponds to the surface morphology of the bone having the bone injury site A; and the plate-shaped part 11 being provided with a through-hole 14 through which a fastener, for fastening the plate-shaped part 11 to a section of bone at the periphery of the bone injury site A, can pass.
The present invention addresses the problem of providing a novel means that is effective in treating infection with norovirus and in preventing the spread of infection with norovirus. Provided is an anti-norovirus agent containing a unicellular algae-derived substance as an active ingredient.
A61K 36/05 - Chlorophycota ou chlorophyta (algues vertes), p. ex. Chlorella
A01N 43/16 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome des cycles à six chaînons avec l'oxygène comme hétéro-atome du cycle
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
A23K 10/16 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61K 31/7032 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un polyol, c.-à-d. composés ayant plusieurs groupes hydroxyle, libres ou estérifiés, y compris le groupe hydroxyle impliqué dans la liaison glycosidique, p. ex. monoglucosyl-diacylglycérides, acide lactobionique, gangliosides
A61K 35/68 - Protozoaires, p. ex. flagelles, amibes, sporozoaires, plasmodium ou toxoplasma
A61K 35/748 - Cyanobactéries, c.-à-d. bactéries bleu-vert ou algues bleu-vert, p. ex. spiruline
The present invention addresses the problem of providing a novel means that is effective in the treatment or the prevention of herpes virus infection. Provided is an anti-herpes virus agent containing a unicellular algae-derived substance as an active ingredient.
A61K 36/05 - Chlorophycota ou chlorophyta (algues vertes), p. ex. Chlorella
A01N 43/16 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome des cycles à six chaînons avec l'oxygène comme hétéro-atome du cycle
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
A23K 10/16 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61K 31/7032 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un polyol, c.-à-d. composés ayant plusieurs groupes hydroxyle, libres ou estérifiés, y compris le groupe hydroxyle impliqué dans la liaison glycosidique, p. ex. monoglucosyl-diacylglycérides, acide lactobionique, gangliosides
A61K 31/7072 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées ayant des groupes oxo liés directement au cycle pyrimidine, p. ex. cytidine, acide cytidylique ayant deux groupes oxo liés directement au cycle pyrimidine, p. ex. uridine, acide uridylique, thymidine, zidovudine
A61K 35/68 - Protozoaires, p. ex. flagelles, amibes, sporozoaires, plasmodium ou toxoplasma
A61K 35/748 - Cyanobactéries, c.-à-d. bactéries bleu-vert ou algues bleu-vert, p. ex. spiruline
The present invention addresses the problem of providing a virucidal agent that has excellent practical utility and that can be used for a variety of purposes, including for infectious diseases in humans. Provided is a virucidal agent containing a monogalactosyldiacylglycerol-containing extract of unicellular algae as an active ingredient.
A61K 36/05 - Chlorophycota ou chlorophyta (algues vertes), p. ex. Chlorella
A01N 43/16 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome des cycles à six chaînons avec l'oxygène comme hétéro-atome du cycle
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
A23K 10/16 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61K 31/7032 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un polyol, c.-à-d. composés ayant plusieurs groupes hydroxyle, libres ou estérifiés, y compris le groupe hydroxyle impliqué dans la liaison glycosidique, p. ex. monoglucosyl-diacylglycérides, acide lactobionique, gangliosides
A61K 35/748 - Cyanobactéries, c.-à-d. bactéries bleu-vert ou algues bleu-vert, p. ex. spiruline
A61P 31/14 - Antiviraux pour le traitement des virus ARN
A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
A61P 31/22 - Antiviraux pour le traitement des virus ADN des virus de l'herpès
Provided is a novel method whereby an amide compound can be produced by highly stereoselectively and efficiently performing amidation between a plurality of amino acids and/or peptides. A compound of general formula (3) is synthesized by forming an amide bond between the carboxyl group on the right side of general formula (1) in a compound represented thereby and the amino group on the left side of general formula (2) in a compound represented thereby, in the presence of a Lewis acid catalyst and a silylating agent [in formulae (1), (2) and (3), each symbol has the same meaning as defined in claims].
C07C 231/02 - Préparation d'amides d'acides carboxyliques à partir d'acides carboxyliques ou à partir de leurs esters, anhydrides ou halogénures par réaction avec de l'ammoniac ou des amines
C07K 1/00 - Procédés généraux de préparation de peptides
56.
IODINE-HOLDING BONE-REPAIRING MATERIAL AND PRODUCTION METHOD THEREFOR
[Problem] To inexpensively provide a highly safe bone-repairing material which holds therein a large amount of iodine ions and thereby stably exhibits high antibacterial properties in vivo over a long period and which is excellent in terms of apatite-forming ability and storability. [Solution] A bone-repairing material characterized by comprising a base constituted of titanium or a titanium alloy and, disposed on the surface of the base, a titanic-acid-salt film constituted of a large number of crystals each having a crystal structure containing calcium ions and iodine ions, the crystals each comprising multiple layers constituted of a Ti-O framework and calcium ions and iodine ions adsorptively held between these layers.
A61L 27/40 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
The present invention facilitates bending and installing, for example, a stacked conductor superconducting cable. When bending a superconducting cable having a stacked structure in which a plurality of stages of tape wires are stacked, a twisting process is performed on the superconducting cable in front of a portion to be bent.
H02G 1/06 - Méthodes ou appareils spécialement adaptés à l'installation, entretien, réparation, ou démontage des câbles ou lignes électriques pour poser les câbles, p. ex. appareils de pose sur véhicule
H01B 12/02 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par leurs formes
H01B 12/16 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par le refroidissement
H01R 4/68 - Connexions à ou entre conducteurs supraconducteurs
58.
NUCLEAR FUSION SYSTEM, NUCLEAR FUSION METHOD, NUCLIDE TRANSMUTATION LIFE-SHORTENING TREATMENT SYSTEM FOR LONG LIVED FISSION PRODUCT, AND NUCLIDE TRANSMUTATION LIFE-SHORTENING TREATMENT METHOD FOR LONG LIVED FISSION PRODUCT
[Problem] To achieve flight-state negative muon nuclear fusion, and to provide a nuclear fusion system and a nuclear fusion method for eliminating major restrictions on devices required for holding and cooling a target, for example, and to provide a nuclide transmutation life-shortening treatment system and a nuclide transmutation life-shortening treatment method capable of irradiating a long lived fission product with neutrons generated by the nuclear fusion system and the nuclear fusion method to effect nuclide transmutation. [Solution] A nuclear fusion system S is provided with a muon generating means 1 for generating muons, a gas supply means 2 for circulating and supplying a feed gas, a de Laval nozzle 3 which accelerates the feed gas to a supersonic speed, and a shock wave generator 4, wherein the feed gas accelerated to a supersonic speed by the de Laval nozzle 3 is caused to collide with the shock wave generator 4 to generate oblique shock waves, the oblique shock waves are caused to converge on the central axis of the de Laval nozzle 3 to hold a high-density gas target in space, and muons generated by the muon generating means 1 are introduced into the high-density gas target to cause a nuclear fusion reaction to occur.
KABUSHIKI KAISHA TOKAI TIKA DENKI SEISA KUSHO (Japon)
Inventeur(s)
Suzuki, Eiji
Hirata, Yutaka
Nakamura, Shogo
Ueda, Shinichi
Yamamoto, Masaya
Abrégé
An eye movement measuring device for detecting an eyeball-state/movement including: an eyeball photographing device configured to take a photograph of an eyeball; and an eye movement detecting unit configured to detect eye movement based on eyeball image as a photograph taken with the eyeball photographing device, the eyeball photographing device including an eyeball illuminating unit configured to illuminate an eyeball of a subject including a driver with illumination light, an eyeball image imaging unit configured to obtain eyeball image as a result of imaging the illuminated eyeball, and an arranging unit configured such that, when the eyeball photographing device is worn by the subject, the eyeball illuminating unit is arranged in a position where the eyeball can be irradiated with the illumination light, and the eyeball image imaging unit is arranged in a position where the eyeball image can be obtained as a result of the imaging.
G08B 7/06 - Systèmes de signalisation selon plus d'un des groupes Systèmes d'appel de personnes selon plus d'un des groupes utilisant une transmission électrique
B60W 50/16 - Signalisation tactile au conducteur, p. ex. vibration ou augmentation de la résistance sur le volant ou sur la pédale d'accélérateur
G02C 11/00 - Accessoires non optiquesFixation de ceux-ci
A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
A61B 5/18 - Dispositifs pour l'exécution des tests de capacité pour conducteurs de véhicules
A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
G06F 3/0346 - Dispositifs de pointage déplacés ou positionnés par l'utilisateurLeurs accessoires avec détection de l’orientation ou du mouvement libre du dispositif dans un espace en trois dimensions [3D], p. ex. souris 3D, dispositifs de pointage à six degrés de liberté [6-DOF] utilisant des capteurs gyroscopiques, accéléromètres ou d’inclinaison
B60K 28/06 - Dispositifs de sécurité pour la commande des ensembles de propulsion spécialement adaptés aux véhicules ou aménagés dans ceux-ci, p. ex. empêchant l'alimentation en carburant ou l'allumage en cas de danger sensibles à des conditions relatives au conducteur sensibles à l'incapacité du conducteur
B60W 50/14 - Moyens d'information du conducteur, pour l'avertir ou provoquer son intervention
60.
Method of installing superconducting cable and former
When temperature raising is performed, temperature of a superconducting cable is uniformly raised over an entirety of the superconducting cable. The superconducting cable assumes a linear shape when cooled, and deforms into a helical shape when temperature raising is performed. In a former having a twisted wire structure, twisting directions of an outermost layer and a layer next to the outer most layer are set to be the same, enabling stabilization of the helical deformation of the superconducting cable including the former when the temperature raising is performed.
H01B 12/00 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs
H01B 12/16 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par le refroidissement
H02G 1/06 - Méthodes ou appareils spécialement adaptés à l'installation, entretien, réparation, ou démontage des câbles ou lignes électriques pour poser les câbles, p. ex. appareils de pose sur véhicule
H01B 12/02 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par leurs formes
61.
METHOD AND DEVICE FOR CONCENTRATING VIRUS OR BACTERIUM USING BIOAFFINITY
The present invention addresses the problem of providing a means for concentrating a virus or a bacterium simply and rapidly while maintaining the structure thereof. Provided is a method for concentrating a target virus or bacterium, the method characterized in that the target virus or bacterium is captured by a carrier via a metal ion-dependent ligand binding molecule, is isolated from the ligand binding molecule by treatment with a chelating agent, and is then recovered.
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12N 1/02 - Séparation des micro-organismes de leurs milieux de culture
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
C07K 16/10 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de virus de virus à ARN
C07K 16/12 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de bactéries
62.
THREE-DIMENSIONAL STRUCTURE WITH BIOLOGICAL ACTIVITY AND PRODUCTION METHOD THEREFOR
The present invention addresses the problem of providing: a three-dimensional structure with biological activity wherein the surface of a three-dimensional structure main body has recesses and/or protrusions and is covered with a coating film comprising a hydrolysis product of a titanium alkoxide with high adhesion strength; and a production method therefor. This three-dimensional structure with biological activity comprises: a three-dimensional structure main body having recesses and/or protrusions on the surface and comprising a polymer; and a 10-200 nm thick coating film formed on the surface of the three-dimensional structure main body and comprising a hydrolysis product of a titanium alkoxide. When the recesses and/or protrusions on the surface of the three-dimensional structure are observed with a scanning electron microscope at a magnification of 300, no cracks or separation of the coating film is observed. The coating film has biological activity when evaluated under the conditions defined by ISO 23317.
The purpose of the present invention is to achieve a binarized neural network processor capable of installing a high-performance, compact model in a low-specification device such as an embedded device or a mobile device, without learning being required. Provided is a binarized neural network processor (1000) wherein a weight computation process is executed by treating the majority of weight computation processes as bit computation processes using a binary base matrix and carrying out a very small quantity of real number computations (multiplication processes using a scaling coefficient vector). Thus, the binarized neural network processor (1000) enables execution of a high-precision weight computation process while restraining increase in hardware scale. Due to the above, the binarized neural network processor (1000) makes it possible to execute a weight computation process commensurate with that of a compact model (an approximation model of a learned model learned and acquired with a large-scale system) without re-learning being required.
Provided is a novel method for producing amide compounds at high stereochemical selectivity. This method for producing amide compounds is provided with an amidation step for reacting an aminoester compound represented by general formula (1) and an amino compound in the presence of a catalyst comprising a metal compound to amidate the ester groups of the aminoester compound.
C07C 249/12 - Préparation de composés contenant des atomes d'azote, liés par des liaisons doubles à un squelette carboné d'oximes par des réactions n'impliquant pas la formation de groupes oxyimino
C07C 231/12 - Préparation d'amides d'acides carboxyliques par des réactions n'impliquant pas la formation de groupes carboxamide
C07C 237/12 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des groupes amino ayant les atomes de carbone des groupes carboxamide liés à des atomes de carbone acycliques du squelette carboné le squelette carboné étant acyclique et saturé ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone acyclique d'un radical hydrocarboné substitué par des groupes carboxyle
C07C 239/08 - Composés hydroxylaminés ou leurs éthers ou esters
C07C 251/38 - Oximes avec des atomes d'oxygène de groupes oxyimino liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués avec les atomes de carbone des groupes oxyimino liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes de carbone d'un squelette carboné saturé
C07C 319/20 - Préparation de thiols, de sulfures, d'hydropolysulfures ou de polysulfures de sulfures par des réactions n'impliquant pas la formation de groupes sulfure
C07C 321/14 - Sulfures, hydropolysulfures ou polysulfures ayant des groupes thio liés à des atomes de carbone acycliques d'un squelette carboné acyclique saturé
C07D 207/16 - Atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
C07D 209/20 - Radicaux substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile substitués en outre par des atomes d'azote, p. ex. tryptophane
Provided is a novel method for producing amide compounds at high stereochemical selectivities. The method according to the present invention for producing amide compounds is provided with an amidation step for reacting, in the presence of a catalyst comprising a metal compound, an amino compound with an aminoester compound represented by general formula (1) to amidate the ester group in the aminoester compound.
C07C 231/02 - Préparation d'amides d'acides carboxyliques à partir d'acides carboxyliques ou à partir de leurs esters, anhydrides ou halogénures par réaction avec de l'ammoniac ou des amines
C07C 237/12 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des groupes amino ayant les atomes de carbone des groupes carboxamide liés à des atomes de carbone acycliques du squelette carboné le squelette carboné étant acyclique et saturé ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone acyclique d'un radical hydrocarboné substitué par des groupes carboxyle
C07C 269/06 - Préparation de dérivés d'acide carbamique, c.-à-d. de composés contenant l'un des groupes l'atome d'azote ne faisant pas partie de groupes nitro ou nitroso par des réactions n'impliquant pas la formation de groupes carbamate
C07C 271/22 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec les atomes d'azote des groupes carbamate liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes de carbone de radicaux hydrocarbonés substitués par des groupes carboxyle
[Problem] To provide: a compact eye movement measuring device that can be easily worn and removed by a driver or the like and is capable of measuring eye movement under a stable condition while reducing the influence of ambient light; and an eye movement analysis system for performing a variety of analyses, such as analysis of the state of consciousness of a driver or the like, on the basis of the eye movement acquired by the eye movement measuring device. [Solution] An eye movement analysis system S is provided with an eye photographing device 1, an eye movement detection means 2, and a human state detection means 3. The eye photographing device 1 is provided with: a pair of over-glasses 10; an eye illumination means 11 for illuminating eyes with non-visible light; an eye imaging means 12 for capturing an image of the eyes illuminated by the eye illumination means 11; a reflection means 13 for guiding the non-visible light to the eyes and reflecting eye images therefrom; and an arrangement means for arranging the eye illumination means 11, the eye imaging means 12, and the reflection means 13 at predetermined positions on a pair of glasses G.
A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
A61B 5/18 - Dispositifs pour l'exécution des tests de capacité pour conducteurs de véhicules
B60K 28/06 - Dispositifs de sécurité pour la commande des ensembles de propulsion spécialement adaptés aux véhicules ou aménagés dans ceux-ci, p. ex. empêchant l'alimentation en carburant ou l'allumage en cas de danger sensibles à des conditions relatives au conducteur sensibles à l'incapacité du conducteur
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
G06F 3/0346 - Dispositifs de pointage déplacés ou positionnés par l'utilisateurLeurs accessoires avec détection de l’orientation ou du mouvement libre du dispositif dans un espace en trois dimensions [3D], p. ex. souris 3D, dispositifs de pointage à six degrés de liberté [6-DOF] utilisant des capteurs gyroscopiques, accéléromètres ou d’inclinaison
67.
CATALYST FOR CONVERTING ESTER TO AMIDE USING HYDROXYL GROUP AS ORIENTATION GROUP
Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal of the group 4 or group 5 in the periodic table, reacting at least one kind of hydroxy ester compound selected from the group consisting of an α-hydroxy ester compound, a β-hydroxy ester compound, a γ-hydroxy ester compound and a δ-hydroxy ester compound with an amino compound so as to amidate an ester group having a hydroxyl group at the α-, β-, γ- or δ-position of the hydroxy ester compound.
C07C 231/02 - Préparation d'amides d'acides carboxyliques à partir d'acides carboxyliques ou à partir de leurs esters, anhydrides ou halogénures par réaction avec de l'ammoniac ou des amines
B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
C07C 235/06 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des atomes d'oxygène ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone acycliques et des atomes d'oxygène, liés par des liaisons simples, liés au même squelette carboné le squelette carboné étant acyclique et saturé ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques
C07C 235/08 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des atomes d'oxygène ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone acycliques et des atomes d'oxygène, liés par des liaisons simples, liés au même squelette carboné le squelette carboné étant acyclique et saturé ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone acyclique d'un radical hydrocarboné substitué par des atomes d'oxygène liés par des liaisons simples
C07C 235/16 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des atomes d'oxygène ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone acycliques et des atomes d'oxygène, liés par des liaisons simples, liés au même squelette carboné le squelette carboné étant acyclique et saturé ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un cycle aromatique à six chaînons
C07C 235/46 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des atomes d'oxygène ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone de cycles aromatiques à six chaînons et des atomes d'oxygène, liés par des liaisons simples, liés au même squelette carboné avec des atomes de carbone de groupes carboxamide et des atomes d'oxygène, liés par des liaisons simples, liés à des atomes de carbone du même cycle aromatique à six chaînons non condensé ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques
C07C 259/06 - Composés contenant des groupes carboxyle, un atome d'oxygène d'un groupe carboxyle étant remplacé par un atome d'azote, cet atome d'azote étant lié de plus à un atome d'oxygène et ne faisant pas partie de groupes nitro ou nitroso sans remplacement de l'autre atome d'oxygène du groupe carboxyle, p. ex. acides hydroxamiques ayant des atomes de carbone de groupes hydroxamique liés à des atomes d'hydrogène ou à des atomes de carbone acycliques
C07C 269/06 - Préparation de dérivés d'acide carbamique, c.-à-d. de composés contenant l'un des groupes l'atome d'azote ne faisant pas partie de groupes nitro ou nitroso par des réactions n'impliquant pas la formation de groupes carbamate
C07C 271/22 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec les atomes d'azote des groupes carbamate liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes de carbone de radicaux hydrocarbonés substitués par des groupes carboxyle
C07D 209/40 - Atomes d'azote ne faisant pas partie d'un radical nitro, p. ex. semicarbazone d'isatine
C07D 307/54 - Radicaux substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
C07D 317/66 - Atomes d'azote ne faisant pas partie d'un radical nitro
C07D 333/24 - Radicaux substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
Provided are a method for laying a superconducting cable, and a former, with which laying can be performed such that helical deformation during heating becomes uniform in the lengthwise direction of the superconducting cable. A superconducting cable, which assumes a linear shape when cooled and deforms to a helical shape when heated, is uniformly heated over the entirety of the superconducting cable. In a former having a twisted-wire structure, the twisting directions in an outermost layer and the next layer are set in the same direction, enabling stabilization of helical deformation during heating of a superconducting cable containing the former.
H02G 1/06 - Méthodes ou appareils spécialement adaptés à l'installation, entretien, réparation, ou démontage des câbles ou lignes électriques pour poser les câbles, p. ex. appareils de pose sur véhicule
H01B 12/16 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par le refroidissement
There have been required medicines which are based on naturally occurring compounds and by which osteopenic diseases can be prevented and/or treated. Provided is a medicinal composition for preventing and/or treating osteopenic diseases, said composition comprising a compound represented by chemical formula (I). In chemical formula (I): R1 represents one functional group or 2-4 functional groups, which are either the same as or different from each other, selected from the group consisting of a hydrogen atom, a hydroxy group and a methoxy group; and R2 and R3 represent a hydrogen atom or a ketone group, provided that either R2 or R3 is a ketone group.
A superconducting power transmission system that comprises an inner pipe housing a superconducting cable therein, a radiation covering at least a part of the inner pipe from outside; and an outer pipe housing the inner pipe and the radiation shield therein. A vacuum is created in a space from an inside of the outer pipe to an outside of the inner pipe with the radiation shield therebetween. The system further comprises at least one radiation shield pipe, housed in the outer pipe and thermally coupled with the radiation shield, a liquefied natural gas (LNG) as a second cryogen for the radiation shield being made to flow through the radiation shield pipe.
H01L 39/24 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement des dispositifs couverts par ou de leurs parties constitutives
H01B 12/00 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs
H01B 12/14 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par la disposition de l'isolation thermique
H01B 12/16 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par le refroidissement
H02G 3/04 - Tubes ou conduits de protection, p. ex. échelles à câbles ou goulottes de câblage
H02G 15/34 - Accessoires de câble pour câbles cryogéniques
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (Japon)
CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (Japon)
Inventeur(s)
Kato Masashi
Yajima Ichiro
Takeda Kozue
Goto Yuji
Abrégé
The present invention addresses the problem of providing: a marker molecule which enables the highly efficient diagnosis of melanoma; and a novel therapy target molecule which can be utilized in an effective therapy method. As melanoma-specific markers, PDZRN3, DTX3L, CSS3 and BRP44L are provided. Also provided are a test method, a therapy method and others each using these biological molecules.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
A61K 31/7105 - Acides ribonucléiques naturels, c.-à-d. contenant uniquement des riboses liés à l'adénine, la guanine, la cytosine ou l'uracile et ayant des liaisons 3'-5' phosphodiester
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61K 38/00 - Préparations médicinales contenant des peptides
A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
The present invention addresses the problem of providing a heating furnace that sufficiently exhibits the microwave effect produced by microwave heating and allows economical heating taking advantage of the characteristics of each heating method. The provided microwave composite heating furnace (1) is equipped with: a housing (10); a heating container (11) for accommodating and heating an object to be heated; a heating means (12) for heating the heating container (11) from the outside; a microwave irradiation device (13); a to-be-heated object supplying device (14) that supplies the object to be heated to the inside of the heating container (11); a gas introducing means (15) for introducing gas into the heating container (11); and a gas recovery means (16) for recovering the gas generated when heating the object to be heated. The heating container (11) comprises a material that has high electrical conductivity so as to reflect microwaves and confine the microwaves inside and that has high heat resistance so as not to react with the heated object, thereby confining microwaves irradiated into the heating container (11) not through the outer wall of the heating container, and allowing an improvement in electromagnetic field density.
F27B 14/14 - Aménagement des dispositifs de chauffage
F27D 11/12 - Aménagement des éléments pour le chauffage électrique dans ou sur les fours avec champs électromagnétiques agissant directement sur le matériau à chauffer
The present invention addresses the problem of providing a means which is effective for the induction of the differentiation of a brown adipocyte and therefore enables a brown adipocyte to be used for and applied to, for example, the prevention/treatment of obesity or metabolic syndrome. Provided is a brown adipocyte differentiation-inducing agent containing, as an active ingredient, (1) CREG1 protein or (2) an expression vector carrying CREG1 gene.
C07K 14/00 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
A61K 38/00 - Préparations médicinales contenant des peptides
A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
74.
Thin film transistor and method for producing same
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (Japon)
OSAKA UNIVERSITY (Japon)
NISSIN ELECTRIC CO., LTD. (Japon)
Inventeur(s)
Kawahara, Toshio
Okamoto, Kazumasa
Matsumoto, Kazuhiko
Utsunomiya, Risa
Matsuba, Teruaki
Matsumoto, Hitoshi
Abrégé
A thin film transistor is equipped with a silicon substrate, a channel layer, a source electrode and a drain electrode. The channel layer, the source electrode and the drain electrode are arranged on the main surface of the silicon substrate. The channel layer is composed of multiple carbon nanowall thin films, wherein the multiple carbon nanowall thin films are arranged in parallel to each other between the source electrode and the drain electrode, one end of each of the multiple carbon nanowall thin films is in contact with the source electrode, and the other end of each of the multiple carbon nanowall thin films is in contact with the drain electrode. An insulating film and a gate electrode are arranged on the rear surface side of the silicon substrate.
H01L 29/66 - Types de dispositifs semi-conducteurs
H01L 29/778 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à deux dimensions, p.ex. transistors à effet de champ à haute mobilité électronique HEMT
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
H01L 29/10 - Corps semi-conducteurs caractérisés par les formes, les dimensions relatives, ou les dispositions des régions semi-conductrices avec des régions semi-conductrices connectées à une électrode ne transportant pas le courant à redresser, amplifier ou commuter, cette électrode faisant partie d'un dispositif à semi-conducteur qui comporte trois électrodes ou plus
This antiviral agent comprises, as an active ingredient, an extract derived from a microalga Pseudochoricystis ellipsoidea Sekiguchi et Kurano gen. et sp. nov. MBIC11204 strain. The microalga may be cultured in a culture medium comprising sufficient nitrogen or may be cultured in a nitrogen-deficient medium thereafter. The extract is extracted from the microalga with alcohol, hot water, etc. as an extractant. The extract may be extracted from the residue thereof with hot water. The antiviral agent may comprise the extract obtained using one extractant or may comprise a mixture of each of the extracts obtained using multiple extractants.
In order to improve thermal insulation performance, for example, to enable the effective use of cold of LNG, a superconducting electric power transmission system configured to be provided with an inner tube (12) housing a superconducting cable (11) therein, a radiation shield (13) covering at least part of the inner tube (12) from outside, and an outer tube (14) housing the inner tube and the radiation shield therein, and maintain a vacuum from the inside of the outer tube (14) to the outside of the inner tube (12) with the radiation shield (13) therebetween is provided with a radiation shield tube (15) housed in the outer tube (14) and provided to be associated with the radiation shield (13), and passes, for example, liquid natural gas (LNG) as a second refrigerant for the radiation shield (13) through the radiation shield tube (15).
H01B 12/16 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par le refroidissement
H01B 12/14 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par la disposition de l'isolation thermique
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (Japon)
OSAKA UNIVERSITY (Japon)
NISSIN ELECTRIC CO., LTD. (Japon)
Inventeur(s)
Kawahara Toshio
Okamoto Kazumasa
Matsumoto Kazuhiko
Utsunomiya Risa
Matsuba Teruaki
Matsumoto Hitoshi
Abrégé
A thin film transistor (10) is provided with a silicon substrate (1), a channel layer (2), a source electrode (3), a drain electrode (4), an insulating film (5), and a gate electrode (6). The channel layer (2), the source electrode (3), and the drain electrode (4) are linearly disposed on a protruding portion of a recessed/protruding shape of the silicon substrate (1), said channel layer, source electrode and the drain electrode being disposed in the longitudinal direction of the protruding portion. The channel layer (2) is formed of a carbon nanowall thin film, and the source electrode (3) and the drain electrode (4) are formed of a metal carbon nanowall thin film. The insulating film (5) is formed of SiO2, and is disposed in contact with the rear surface of the silicon substrate (1). The gate electrode (6) is formed of a Ti/Au laminated structure, and is disposed in contact with the insulating film (5).
H01L 21/205 - Dépôt de matériaux semi-conducteurs sur un substrat, p. ex. croissance épitaxiale en utilisant la réduction ou la décomposition d'un composé gazeux donnant un condensat solide, c.-à-d. un dépôt chimique
H01L 21/336 - Transistors à effet de champ à grille isolée
H01L 29/78 - Transistors à effet de champ l'effet de champ étant produit par une porte isolée
H01L 51/05 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés au redressement, à l'amplification, à la génération d'oscillations ou à la commutation et ayant au moins une barrière de potentiel ou une barrière de surface; Condensateurs ou résistances à l'état solide, ayant au moins une barrière de potentiel ou une barrière de surface
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (Japon)
OSAKA UNIVERSITY (Japon)
NISSIN ELECTRIC CO., LTD. (Japon)
Inventeur(s)
Kawahara Toshio
Okamoto Kazumasa
Matsumoto Kazuhiko
Utsunomiya Risa
Matsuba Teruaki
Matsumoto Hitoshi
Abrégé
A thin film transistor (10) is equipped with a silicon substrate (1), a channel layer (2), a source electrode (3) and a drain electrode (4). The channel layer (2), the source electrode (3) and the drain electrode (4) are arranged on one main surface of the silicon substrate (1). The channel layer (2) is composed of multiple carbon nano-wall thin films (21 to 25), wherein the multiple carbon nano-wall thin films (21 to 25) are arranged in parallel to each other between the source electrode (3) and the drain electrode (4), one end of each of the multiple carbon nano-wall thin films (21 to 25) is in contact with the source electrode (3), and the other end of each of the multiple carbon nano-wall thin films (21 to 25) is in contact with the drain electrode (4). An insulating film and a gate electrode are arranged on the rear surface side of the silicon substrate (1).
The present invention addresses the problem of providing a means which is effective for the induction of the differentiation of a brown adipocyte and therefore enables a brown adipocyte to be used for and applied to, for example, the prevention/treatment of obesity or metabolic syndrome. Provided is a brown adipocyte differentiation-inducing agent containing, as an active ingredient, (1) CREG1 protein or (2) an expression vector carrying CREG1 gene.
A61K 38/00 - Préparations médicinales contenant des peptides
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
80.
BONE REPAIR MATERIAL AND PRODUCTION METHOD THEREFOR
[Problem] To provide a highly safe bone repair material that gradually releases bone-forming ions and that exhibits excellent apatite-forming ability and storability. [Solution] The production method of the present invention is characterized by comprising: a step in which a substrate comprising titanium or a titanium alloy is immersed in an alkaline first aqueous solution that contains cations of sodium ions and/or potassium ions and that does not contain calcium ions or bone-forming ions; a step in which the substrate is immersed in a second solution that contains calcium ions and at least one kind of bone-forming ions selected from among strontium ions, magnesium ions, zinc ions, lithium ions, and gallium ions; a step in which the substrate is heated in a dry atmosphere; and a step in which the substrate is immersed in a third aqueous solution containing at least one of water, an acidic aqueous solution, and/or an aqueous solution containing bone-forming ions.
The present invention provides: a superconductive cable having a structure that enables the absorption of thermal shrinkage upon cooling; and a method for installing the superconductive cable. A superconductive cable comprising a former and a superconductive wire material that is wound around an outer layer of the former with an insulating layer intercalated therebetween. The superconductive cable can have a helical form that turns in the direction of the length of the cable at ambient temperature, and can have a linear form at a lower temperature.
In a thermally insulated double pipe, a structure is provided in which an inner pipe may be prevented from being appreciably offset relative to an outer pipe due to thermal contraction. The structure includes an inner pipe 101, within which a superconducting cable is mounted, an outer pipe 103 within which the inner pipe is housed, with the inner and outer pipes constituting a thermally insulated double pipe, and an inner pipe support member 104 supporting the inner pipe. The inner pipe support member 104 is secured to the inner and outer pipes.
A thermoelectric-cooling type current lead (200) is provided with a thermoelectric semiconductor element (220), and a heat-generation-side current terminal (210) and a heat-absorption-side current terminal (230) that are electrodes connected at both ends of the thermoelectric semiconductor element (220) in the current-flowing direction thereof. In this thermoelectric-cooling type current lead (200), the end section (211) is divided into four regions with slits (212, 213), to form four junction faces (214a-214d). The end section (231) of the heat-absorption-side current terminal (230) is divided into four regions with slits (232, 233), to form four junction faces (234a-234d). The thermoelectric semiconductor element (220) is also divided into four, in accordance with the dividing of the end section (211) of the heat-generation-side current terminal (210) and the end section (231) of the heat-absorption-side current terminal (230). Each of the corresponding sets of junction faces is joined together by soldering or the like.
H01L 35/16 - Emploi d'un matériau spécifié pour les bras de la jonction utilisant des compositions inorganiques comprenant du tellure, du sélénium, ou du soufre
H01L 35/32 - DISPOSITIFS À SEMI-CONDUCTEURS; DISPOSITIFS ÉLECTRIQUES À L'ÉTAT SOLIDE NON PRÉVUS AILLEURS - Détails fonctionnant exclusivement par effet Peltier ou effet Seebeck caractérisés par la structure ou la configuration de la cellule ou du thermocouple constituant le dispositif
84.
CARBON NANOWALL ARRAY AND METHOD FOR MANUFACTURING CARBON NANOWALL
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (Japon)
OSAKA UNIVERSITY (Japon)
NISSIN ELECTRIC CO., LTD. (Japon)
Inventeur(s)
Kawahara Toshio
Okamoto Kazumasa
Matsumoto Kazuhiko
Utsunomiya Risa
Matsuba Teruaki
Matsumoto Hitoshi
Abrégé
A carbon nanowall array (10) is provided with a substrate (1) and carbon nanowalls (2-9). The substrate (1) is composed of silicon. The substrate (1) includes protruding portions (11) and recessed portions (12). The protruding portions (11) and the recessed portions (12) are formed in the direction (DR1) on one surface of the substrate (1). The protruding portions (11) and the recessed portions (12) are alternately formed in the direction (DR2) perpendicular to the direction (DR1). Each of the protruding portions (11) has a length of 0.1-0.5 μm in the direction (DR2), and each of the recessed portions (12) has a length of 0.6-1.5 μm in the direction (DR2). The height of each of the protruding portions (11) is 0.3-0.6 μm. Respective carbon nanowalls (2-9) are formed in the length direction (i.e., the direction (DR1)) of the protruding portions (11) of the substrate (1), said carbon nanowalls being formed on the protruding portions (11).
A rotary optical link joint having a small change in transmission loss during rotational use is provided. In order to realize this, the rotary optical link joint according to the present invention is an optical link joint that relatively rotatably holds, centering around an axis line (19, 29), a first optical fiber (11) and a second optical fiber (21), wherein a part or all of the first optical fiber (11) and the second optical fiber (21) are configured by a multi-core optical fiber having a plurality of cores, and wherein the plurality of cores is arranged in a circular or annular area that is sectioned by a concentric circle centered around the axis line (19, 29) of the multi-core optical fiber.
Provided is a superconductive cable that can hold the differences in the number of HTS tape wire materials for a round-trip with the same current to a minimum, lower costs, and make the critical current large. A plurality of HTS tape wire materials, for which a first and second layer of HTS tape wire material are provided and in which each of the first and second layers is disposed with a predetermined prescribed gap in the direction of the width of the HTS tape wire material, is provided. Either or both of the HTS tape wire materials for the first layer and second layer have a region in which the gap adjacent to the other layer and a part of the HTS tape wire material overlap.
Provided is a current lead device for suppressing the infiltration of heat. A pipe (12) surrounds a current lead (11) that is connected between a low-temperature-side terminal and a normal-temperature-side terminal, and refrigerant gas flows in the pipe (12) from the low temperature side to the high temperature side and causes heat exchange. The refrigerant gas discharged on the normal temperature side passes through coolers (3, 2) in a plurality of stages and is circulated to the low temperature side of the pipe (12).
H02G 15/34 - Accessoires de câble pour câbles cryogéniques
H01L 35/30 - DISPOSITIFS À SEMI-CONDUCTEURS; DISPOSITIFS ÉLECTRIQUES À L'ÉTAT SOLIDE NON PRÉVUS AILLEURS - Détails fonctionnant exclusivement par effet Peltier ou effet Seebeck caractérisés par les moyens d'échange de chaleur à la jonction
A sleepiness sign detection apparatus, includes: a head movement detection unit configured to detect a head movement to generate a head movement data; an eye movement detection unit configured to detect an eye movement to generate an eye movement data; an ideal eye movement angular velocity calculation unit configured to calculate an ideal eye movement angular velocity based on the head movement data generated by the head movement detection unit; an eye-rotation angular velocity calculation unit configured to calculate an eye-rotation angular velocity based on the eye movement data generated by the eye movement detection unit; and a sleepiness sign detection unit configured to detect vestibule-ocular reflex (VOR) from the ideal eye movement angular velocity and the eye-rotation angular velocity, and determine a sign of sleepiness based on the vestibule-ocular reflex.
Provided is a structure that avoids large offsetting from an outer pipe due to thermal contraction of an inner pipe in a double insulated pipe. Specifically provided are a double insulated pipe, comprising an inner pipe (101) in which a superconducting cable is disposed within the pipe and an outer pipe (103) that accommodates the inner pipe within the pipe, and a inner pipe support member (104) that supports the inner pipe. The inner pipe support member (104) is affixed to the inner pipe and the outer pipe.
H01B 12/14 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par la disposition de l'isolation thermique
H01B 12/16 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par le refroidissement
Provided are a neuraminic acid derivative, which selectively inhibits virus sialidase activity but little inhibits human sialidase activity, a sialidase activity inhibitor, and an antiinfluenza drug. The aforesaid neuraminic acid derivative is characterized by comprising a compound represented by chemical formula (1), a pharmaceutically acceptable salt thereof, a hydrate of the same, a solvate of the same or a prodrug of the same. In chemical formula (1), R1 and R2 represent hydrogen, an optionally branched C1-8 alkyl group or an optionally branched C1-8 cycloalkyl group; and R3 represents hydrogen or fluorine.
C07D 309/28 - Composés hétérocycliques contenant des cycles à six chaînons comportant un atome d'oxygène comme unique hétéro-atome du cycle, non condensés avec d'autres cycles comportant une liaison double entre chaînons cycliques ou entre chaînon cyclique et chaînon non cyclique avec des hétéro-atomes ou avec des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement aux atomes de carbone du cycle
A61K 31/351 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle non condensés avec un autre cycle
A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
91.
Superconducting tape wire material and method of manufacturing same
A method of manufacturing a superconducting tape wire, wherein a reduction in critical current in the superconducting tape wire and the effective AC loss are suppressed. To manufacture the superconducting tape wire, the filaments filled with superconducting material powder and having a flat elliptic or rectangular cross section are disposed in a pipe having a shape whose sides in a pressing direction have a smaller length than adjacent sides, and then the pipe is compressed in the short-side direction to form the pipe in a tape shape.
H01L 39/24 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement des dispositifs couverts par ou de leurs parties constitutives
H01L 39/14 - Dispositifs à supraconductivité permanente
Disclosed is an optical rotary joint with which transmission loss does not change significantly during rotation of fibers. Specifically disclosed is an optical rotary joint that holds a first optical fiber (11) and a second optical fiber (21) such that the optical fibers can rotate about the axes (19, 29), respectively, relative to each other. The first optical fiber (11) and the second optical fiber (21) are partially or entirely formed of multicore optical fibers including a plurality of cores, and the plurality of cores are disposed in a cicular or annular area sectioned by concentric circles having centers at the axes (19, 29) of the multicore optical fibers.
G02B 6/38 - Moyens de couplage mécaniques ayant des moyens d'assemblage fibre à fibre
G02B 6/04 - Guides de lumièreDétails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p. ex. des moyens de couplage formés par des faisceaux de fibres
Provided is an arrangement whereby object detection accuracy is improved in an object detection device which detects objects from images inputted. Distance information representing the distance to a photographic subject is obtained; distance images are obtained wherein information in individual pixels consists of distance information; the distance information in pixels included in specified regions in distance images is classified according to specified dimensions, thereby preparing distance histograms; the degree of similarity of distance histograms in two specified regions located in different places in distance images is calculated as a feature quantity; high-certainty distance images for learning are classed as positive instances; low-certainty distance images for learning are classed as negative instances; an identification apparatus suited to identify the aforementioned instances is constructed; furthermore, by using the identification apparatus, the object which is the subject of detection is detected from distance images on the basis of the feature quantity.
Provided is a bone-repairing material which shows little ion elution in vivo and has excellent apatite-forming ability and apatite peeling-off resistance and high scratch resistance from a practical standpoint. A bone-repairing material which comprises a base material comprising titanium or a titanium alloy and a surface layer substantially comprising titanium oxide, characterized in that peaks and valleys that are 1 nm to 10 μm inclusive on average, both in width and height, are formed on the surface and the surface layer has a zeta potential of 4.5 mV or more in a pH 6-8 aqueous solution environment. When a stylus having a constant of spring of 200 g/mm is vibrated at an amplitude of 100 μm on the surface layer and moved thereon at a speed of 10 mm/sec under a load of 100 mN/min, the surface layer has a critical scratch resistance of at least 35 mN.
Amorphous carbon according to the invention contains hydrogen at a concentration in a range of 5 atomic percent to 30 atomic percent, and a doping element. It exhibits a low electrical resistivity.
C23C 16/511 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement au moyen de décharges électriques utilisant des décharges à micro-ondes
H01L 31/028 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des éléments du groupe IV de la classification périodique
Disclosed is a sleepiness signal detector for detecting a signal, which appears before the driver of a vehicle or the operator of a machine is aware of sleepiness, over a wide range of practical conditions. The sleepiness signal detector (10) is designed such that a head movement detection means (11) detects a head movement, an eyeball movement detection means (12) detects an eyeball movement, a means (13) for calculating the ideal angular velocity of an eyeball movement calculates an ideal angular velocity of an eyeball movement based on the head movement data detected by the head movement detection means (11), a means (14) for calculating the angular velocity of an eyeball rotation calculates the angular velocity of an eyeball rotation based on the eye movement data detected by the eyeball movement detection means (12), and a means (15) for determining a sleepiness signal can detect vestibulo-ocular reflex from the ideal angular velocity of eyeball movement and the angular velocity of eyeball rotation, and determine a sleepiness signal based on the vestibulo-ocular reflex before the driver of a vehicle or the operator of a machine is aware of sleepiness.
A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
B60R 11/04 - Montage des caméras pour fonctionner pendant la marcheDisposition de leur commande par rapport au véhicule
G08B 21/06 - Alarmes pour assurer la sécurité des personnes indiquant un état de sommeil, p. ex. alarmes contre l'assoupissement
Disclosed is a bone-repairing material having excellent apatite-forming power, excellent storage stability and high scratch resistance. A method for producing a bone-repairing material is characterized by comprising a step of immersing a base composed of titanium or a titanium alloy into an alkaline first aqueous solution which contains one or more kinds of cations selected from sodium ions and potassium ions but does not contain calcium ions; a step of immersing the base into a second aqueous solution which contains calcium ions but does not contain phosphate ions; a step of heating the base in a dry atmosphere; and a step of treating the base with hot water of not less than 60˚C or water vapor.
A method of manufacturing a superconducting tape wire material, wherein a reduction in a critical current in the superconducting tape wire material is suppressed by suppressing an increase in an effective AC loss. To manufacture the superconducting tape wire material, filaments filled with superconducting material powder and having a flat elliptic or rectangular cross section are disposed in a pipe having a shape the sides of which in a pressing direction have a smaller length than adjacent sides, and then the pipe is pressed in the short-side direction to form the pipe in a tape shape.
H01B 13/00 - Appareils ou procédés spécialement adaptés à la fabrication de conducteurs ou câbles
H01B 12/10 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par leurs formes à plusieurs filaments enrobés dans des conducteurs normaux
It is intended to provide an artificial bone which can be easily bound to a living bone and is similar in mechanical properties to living bones. Namely, an artificial bone comprising a dense part, which is made of titanium or a titanium alloy, is in a frame shape simulating a part of the outer face of a living bone and has a density of 95% or higher, and a porous part, which is made up of sintered particles of titanium or a titanium alloy having either the same or different composition as the above described titanium alloy, has a shape simulating the remainder of the living bone as described above and has a porosity of 40% or higher, characterized in that the dense part and the particles in the porous part are sintered together at the interface between the dense part and the porous part.
It is intended to provide an artificial bone which is closely similar to a vital bone both in appearance and properties and excellent in osteoconductive property and osteoinductive property. A method characterized by comprising: the extraction step of extracting part(s) corresponding to a spongy bone and/or a cortical bone from digitalized three-dimensional image data of a vital bone (Fig. 1(a)) and determining a center line (Fig. 1(b)); the image-forming step of drawing a beam or a wall having an even diameter or a large thickness along the center line determined above to thereby present artificial bone image data (Fig. 1(c)); the modeling step of laser-sintering a metal powder and piling sintered layers based on the artificial bone image data presented above; and the step of treating the bone model with an alkali followed by heating, or optionally treating it with alkali, and dealkalizing before heating, or conducting the dealkalization and heating at the same time.
brevets
