Abrégé

The present invention relates to fish-protein hydroysates used in preventing and/or treating metabolic disorders, such as metabolic syndrome particularly associated with obesity. According to the invention, the fish-protein hydrolysates are obtained by means of the enzymatic hydrolysis of at least one protein source selected from the group including the following fish: Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus,Trisopterus esmarki, Trachurus spp., Gadus morhua, Pollachius virens, Melanogrammus aeglefinus, Coryphaenoides rupestris, and fish belonging to order Siluriformes, wherein said enzymatic hydrolysis is carried out using an endopeptidase enzyme derived from Bacillus subtilis.

Classes IPC  ?

• A23L 1/327 - Extraits de poisson
• A61K 35/60 - Poissons, p. ex. hippocampesŒufs de poisson
• A61K 38/01 - Protéines hydrolyséesLeurs dérivés
• A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme

Abrégé

The present invention relates to fish protein hydrolysates for the use thereof in inducing weight loss and in limiting and/or inhibiting weight gain. The invention also relates to such hydrolysates in preventing and/or treating besity and/or health problems linked to obesity. The protein hydrolysates according to the invention are obtained by the enzymatic hydrolysis of at least one protein source selected from among the group comprising the following fish: Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki, Trachurus spp., Gadus morhua, Pollachius virens, Melanogrammus aeglefinus, Coryphaenoides rupestris, which belong to order Siluriformes, said enzymatic hydrolysis being performed by an endopeptidase enzyme derived from Bacillus subtilis.

Classes IPC  ?

• A23L 1/305 - Aminoacides, peptides ou protéines 
• A61K 35/60 - Poissons, p. ex. hippocampesŒufs de poisson
• A61P 3/04 - AnorexigènesMédicaments de l'obésité

Abrégé

The present invention relates to a fish protein hydrolysate containing molecules capable of exerting a satietogenic activity and of regulating food intake in humans or animals. More specifically, the protein hydrolysate according to the invention enables stimulation of the secretion of endogenous cholescystokinins (CCKs) and of endogenous glucagon-like peptide 1 (GLP1) molecules by intestinal cells and the supply of exogenous CCKs. The fish protein hydrolysate according to the invention is obtained by enzymatic hydrolysis of at least one protein source selected from the group composed of the pelagic fish species Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki and Trachurus spp., the demersal fish species Gadus morhua, Pollachius virens, Melanogrammus aeglefinus and Coryphaenoides rupestris, and the species of fish belonging to the order Siluriformes, said enzymatic hydrolysis being carried out by means of a mixture of enzymes comprising endopeptidases derived from Bacillus amyloliquefaciens and from Bacillus licheniformis, or derived from Bacillus amyloliquefaciens, from Bacillus licheniformis and from Aspergillus oryzae.

Classes IPC  ?

• C12P 21/06 - Préparation de peptides ou de protéines préparés par hydrolyse d'une liaison peptidique, p. ex. hydrolysats
• A23J 3/34 - Traitement des protéines pour l'alimentation par hydrolyse utilisant des agents chimiques utilisant des enzymes
• A61K 35/60 - Poissons, p. ex. hippocampesŒufs de poisson
• A61K 38/01 - Protéines hydrolyséesLeurs dérivés
• C07K 14/595 - GastrinesCholécystokinines [CCK]

Abrégé

The present invention relates to a fish protein hydrolysate having a biological activity of interest, in particular an effect on the stimulation and maintenance of bone. The fish protein hydrolysate is characterized in that it is obtained by enzymatic hydrolysis of at least one protein source selected from the fish species Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki, Trachurus spp, Gadus morhua, Pollachius virens, Melanogrammus aeglefinus and Coryphaenoides rupestris, and the species of fish belonging to the order Siluriformes, said enzymatic hydrolysis being carried out by means of an endopeptidase enzyme derived from Bacillus subtilis. The protein hydrolysate according to the invention makes it possible to maintain the bone mass or to stimulate bone growth through stimulation of osteoblast cell growth and inhibition of osteoclast cell growth.

Classes IPC  ?

• C12P 21/06 - Préparation de peptides ou de protéines préparés par hydrolyse d'une liaison peptidique, p. ex. hydrolysats
• A23J 3/34 - Traitement des protéines pour l'alimentation par hydrolyse utilisant des agents chimiques utilisant des enzymes
• A61K 38/01 - Protéines hydrolyséesLeurs dérivés