Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.
A61M 1/14 - Systèmes de dialyseReins artificielsOxygénateurs du sang
A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
A61M 1/26 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes en mouvement
A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p. ex. adaptation de la température, irradiation
A61M 60/109 - Pompes extracorporelles, c.-à-d. que le sang est pompé à l’extérieur du corps du patient incorporées dans des circuits ou des systèmes sanguins extracorporels
A61M 60/279 - Pompes péristaltiques, p. ex. pompes à rouleau
A61M 60/37 - Hémodialyse, hémofiltration ou diafiltration
A61M 60/438 - Détails concernant l’entraînement pour les pompes pour le sang à déplacement positif la force agissant sur l’élément en contact avec le sang étant mécanique
A61M 60/835 - Détails structurels autres que ceux relatifs à l’entraînement de la pompe dans les pompes pour le sang à déplacement positif
A61M 60/847 - Détails structurels autres que ceux relatifs à l’entraînement de la pompe des pompes pour le sang extracorporelles disposés dans une cassette
2.
HEMODIALYSIS SYSTEM WITH VARIABLE DIALYSATE FLOW RATE
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient through the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. Preferably, the hemodialysis system includes a sorbent filter in the dialysate flow path. Furthermore, the hemodialysis machine includes a blood pump, and a pair of dialysate pumps. A processor controls the flow of blood through the blood flow path, and the processor controls the flow of dialysate through the dialysate flow path. In addition, the processor stores a patient treatment plan wherein the flow rate of dialysate reduces throughout treatment to maximize the amount of urea removed by the sorbent filter.
A degassing module that may be used in conjunction with a sorbent regeneration cartridge is described. The degassing module may include an air inlet port, a fluid outlet port, a gas outlet port, first and second channels located in an interior chamber, a port connecting the first and second channels, and a hydrophobic membrane positioned above the second channel. The first channel may be in fluid communication with the air inlet port and the second channel may be in communication with the fluid outlet port. In some embodiments, each of the first and second channels may have a spiral configuration.
A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
A61M 1/14 - Systèmes de dialyseReins artificielsOxygénateurs du sang
B01D 15/38 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction spécifique non couverte par un ou plusieurs des groupes , p. ex. chromatographie d'affinité, chromatographie d'échange par ligand ou chromatographie chirale
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path, a closed loop dialysate flow path, a blood pump, and a pair of dialysate pumps. A processor controls the flow of blood through the blood flow path, and the processor controls the flow of dialysate through the dialysate flow path. In addition, the processor stores a preprogrammed patient treatment plan wherein the flow rate of the dialysate through the dialysate flow path reduces throughout the patient's treatment to maximize the amount of urea removed by the sorbent filter. In alternative embodiments, the processor stores a patient treatment plan wherein the dialysate flow rate increases throughout the patient's treatment. In still alternative embodiments, the processor stores a patient treatment plan wherein the flow rate of the dialysate through the dialysate flow path both increases and decreases throughout the patient's treatment.
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient through the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. Preferably, the hemodialysis system includes a sorbent filter in the dialysate flow path. Furthermore, the hemodialysis machine includes a blood pump, and a pair of dialysate pumps. A processor controls the flow of blood through the blood flow path, and the processor controls the flow of dialysate through the dialysate flow path. In addition, the processor stores a patient treatment plan wherein the flow rate of the dialysate through the dialysate flow path reduces throughout the patient's treatment to maximize the amount of urea removed by the sorbent filter.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing medical record analysis relating to the treatment of patients; Providing reports regarding medical record analysis relating to the treatment of patients; Providing a website featuring medical information in the field of medical devices; Providing information, advice and data regarding medical devices relating to the treatment of patients; Health care services, namely, providing a database in the field of hemodialysis information and featuring inputting and collection of data and information all for treatment and diagnostic purposes
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Conducting medical studies for research purposes; New product research and development services in the field of medical equipment; conducting medical studies in the nature of medical and scientific research in the field of hemodialysis; Development of new products in the field of hemodialysis Conducting medical studies in the field of hemodialysis system
A degassing module that may be used in conjunction with a sorbent regeneration cartridge is described. The degassing module may include an air inlet port, a fluid outlet port, a gas outlet port, first and second channels located in an interior chamber, a port connecting the first and second channels, and a hydrophobic membrane positioned above the second channel. The first channel may be in fluid communication with the air inlet port and the second channel may be in communication with the fluid outlet port. In some embodiments, each of the first and second channels may have a spiral configuration.
A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
A61M 1/14 - Systèmes de dialyseReins artificielsOxygénateurs du sang
B01D 15/38 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction spécifique non couverte par un ou plusieurs des groupes , p. ex. chromatographie d'affinité, chromatographie d'échange par ligand ou chromatographie chirale
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is measured by a preferred level sensor having a strain measuring device which includes a load cell and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate measurements of the load cell caused by the tilt.
A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
A61M 1/14 - Systèmes de dialyseReins artificielsOxygénateurs du sang
A61M 60/113 - Pompes extracorporelles, c.-à-d. que le sang est pompé à l’extérieur du corps du patient incorporées dans des circuits ou des systèmes sanguins extracorporels dans d’autres dispositifs fonctionnels, p. ex. dialyseurs ou cœurs-poumons artificiels
A61M 60/37 - Hémodialyse, hémofiltration ou diafiltration
A61M 1/26 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes en mouvement
A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p. ex. adaptation de la température, irradiation
A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c.-à-d. hémofiltration, diafiltration
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient through the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. Preferably, the hemodialysis system comprises a sorbent filter in the dialysate flow path. Furthermore, the hemodialysis system comprises a dialysate quality sensor disposed directly in the dialysate flow path. The dialysate quality sensor is configured to change color based on a pH level, ammonia level, or ammonium level of the dialysate.
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient through the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. Preferably, the hemodialysis system includes a sorbent filter in the dialysate flow path. Furthermore, the hemodialysis machine includes a blood pump, and a pair of dialysate pumps. A processor controls the flow of blood through the blood flow path, and the processor controls the flow of dialysate through the dialysate flow path. In addition, the processor stores a patient treatment plan wherein the flow rate of the dialysate through the dialysate flow path reduces throughout the patient's treatment to maximize the amount of urea removed by the sorbent filter.
A portable hemodialysis system is provided comprising a dialyzer, having a dialysate- replenishing system for replenishing minerals of dialysate in the dialyzer, the dialysate- replenishing system includes: a sorbent filter configured to remove ammonia from the dialysate, the sorbent filter having an outlet that outputs the dialysate to a dialysate flow path; a first reagent source containing a first reagent solution; a first pump configured to inject the first reagent solution into the dialysate flow path; a first mixer coupled to the dialysate flow path and downstream of the first pump, the first mixer configured to mix the dialysate with the first reagent solution; a conductivity sensor configured to measure a level of dissolved solids in the dialysate after the first mixer; and a controller configured to adjust a flow rate of the first reagent solution by adjusting the first pump based at least on the level of measured levels.
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient through the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. Preferably, the hemodialysis system comprises a sorbent filter in the dialysate flow path. Furthermore, the hemodialysis system comprises a dialysate quality sensor disposed directly in the dialysate flow path. The dialysate quality sensor is configured to change color based on a pH level, ammonia level, or ammonium level of the dialysate.
A portable hemodialysis system is provided comprising a dialyzer, having a dialysate- replenishing system for replenishing minerals of dialysate in the dialyzer, the dialysate- replenishing system includes: a sorbent filter configured to remove ammonia from the dialysate, the sorbent filter having an outlet that outputs the dialysate to a dialysate flow path; a first reagent source containing a first reagent solution; a first pump configured to inject the first reagent solution into the dialysate flow path; a first mixer coupled to the dialysate flow path and downstream of the first pump, the first mixer configured to mix the dialysate with the first reagent solution; a conductivity sensor configured to measure a level of dissolved solids in the dialysate after the first mixer; and a controller configured to adjust a flow rate of the first reagent solution by adjusting the first pump based at least on the level of measured levels.
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient through the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. Preferably, the hemodialysis system comprises a sorbent filter in the dialysate flow path. Furthermore, the hemodialysis system comprises a dialysate quality sensor disposed directly in the dialysate flow path. The dialysate quality sensor is configured to change color based on a pH level, ammonia level, or ammonium level of the dialysate.
A portable hemodialysis system is provided comprising a dialyzer, having a dialysate-replenishing system for replenishing minerals of dialysate in the dialyzer, the dialysate-replenishing system includes: a sorbent filter configured to remove ammonia from the dialysate, the sorbent filter having an outlet that outputs the dialysate to a dialysate flow path; a first reagent source containing a first reagent solution; a first pump configured to inject the first reagent solution into the dialysate flow path; a first mixer coupled to the dialysate flow path and downstream of the first pump, the first mixer configured to mix the dialysate with the first reagent solution; a conductivity sensor configured to measure a level of dissolved solids in the dialysate after the first mixer; and a controller configured to adjust a flow rate of the first reagent solution by adjusting the first pump based at least on the level of measured levels.
Sorbent regeneration systems for use in dialysis machines are described. Sorbent regeneration cartridges may include a layer of urease, a layer of acid zirconium phosphate, and a layer of sodium zirconium phosphate. An apparatus for conducting dialysis may include a sorbent cartridge, and a dialyzer in fluid communication with the sorbent cartridge, wherein spent dialysate passes from the dialyzer to and through the sorbent cartridge, and wherein the sorbent cartridge comprises a layer of urease, a layer of acid zirconium phosphate, and a layer of sodium zirconium phosphate. The urease may be immobilized to or associated with a carrier.
A61M 1/14 - Systèmes de dialyseReins artificielsOxygénateurs du sang
A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p. ex. adaptation de la température, irradiation
B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
Sorbent regeneration systems for use in dialysis machines are described. Sorbent regeneration cartridges may include a layer of urease, a layer of acid zirconium phosphate, and a layer of sodium zirconium phosphate. An apparatus for conducting dialysis may include a sorbent cartridge, and a dialyzer in fluid communication with the sorbent cartridge, wherein spent dialysate passes from the dialyzer to and through the sorbent cartridge, and wherein the sorbent cartridge comprises a layer of urease, a layer of acid zirconium phosphate, and a layer of sodium zirconium phosphate. The urease may be immobilized to or associated with a carrier.
A61M 1/14 - Systèmes de dialyseReins artificielsOxygénateurs du sang
A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p. ex. adaptation de la température, irradiation
B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
A degassing module that may be used in conjunction with a sorbent regeneration cartridge is described. The degassing module may include an air inlet port, a fluid outlet port, a gas outlet port, first and second channels located in an interior chamber, a port connecting the first and second channels, and a hydrophobic membrane positioned above the second channel. The first channel may be in fluid communication with the air inlet port and the second channel may be in communication with the fluid outlet port. In some embodiments, each of the first and second channels may have a spiral configuration.
Sorbent regeneration systems for use in dialysis machines are described. Sorbent regeneration cartridges may include a layer of urease, a layer of acid zirconium phosphate, and a layer of sodium zirconium phosphate. An apparatus for conducting dialysis may include a sorbent cartridge, and a dialyzer in fluid communication with the sorbent cartridge, wherein spent dialysate passes from the dialyzer to and through the sorbent cartridge, and wherein the sorbent cartridge comprises a layer of urease, a layer of acid zirconium phosphate, and a layer of sodium zirconium phosphate. The urease may be immobilized to or associated with a carrier.
A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
A degassing module that may be used in conjunction with a sorbent regeneration cartridge is described. The degassing module may include an air inlet port, a fluid outlet port, a gas outlet port, first and second channels located in an interior chamber, a port connecting the first and second channels, and a hydrophobic membrane positioned above the second channel. The first channel may be in fluid communication with the air inlet port and the second channel may be in communication with the fluid outlet port. In some embodiments, each of the first and second channels may have a spiral configuration.
A syringe pump to deliver heparin to into the blood circuit of a hemodialysis system. The syringe pump is configured to receive a syringe having a plunger movable within a lumen of an elongate tubular member. The syringe pump may include a housing having a recess configured to receive at least a portion of the syringe, a drive mechanism for moving the plunger within the lumen, the drive mechanism comprising a motor and a lead screw; and a grabber mechanism. The grabber mechanism includes a control arm, back panel, and upper and lower control fingers, the control fingers each have first and second ends, and a curved portion therebetween having a width, an interior edge, and an exterior edge, wherein the first ends of the upper and lower control fingers are coupled to the control arm via first and second spring hinges.
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient, to the dialyzer, and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. The hemodialysis system includes a hemodialysis machine and dialysate generator which are physically connectable to, and disconnectable from, one another. To connect the hemodialysis machine and dialysate generator together, both the hemodialysis machine and dialysate generator possess connectable and disconnectable electrical connectors and fluid connectors which are positioned and constructed to allow both a fluid and electrical connection between the two machines. The hemodialysis machine includes a processor and a user interface, preferably in the form of a touchscreen, that is capable of controlling both the functions of the hemodialysis machine and the dialysate generator.
Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.
F16L 37/08 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage
F16L 37/14 - Raccords par insertion d'un élément entre surfaces à unir, p. ex. par un bout de fil, une goupille, une chaîne
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is measured by a preferred level sensor having a lever arm, a load cell, and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate measurements of the load cell caused by the tilt.
A connector for use with a dialyzer to connect a conduit from a dialyzer with a conduit from a dialysate source. The connector includes a sleeve (female component) and a collet (male component). The sleeve has a generally cylindrical shape with an opening at one end having a circular shape with at least one slot positioned along the periphery of the circular shape. The sleeve also includes at least one flexible finger having a barb at a free end. The collet is configured to be housed within an interior chamber of the sleeve and has first and second gaps to house the barbs and first and second deflectable flanges to lock into recesses in a conduit.
A61M 1/26 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes en mouvement
F16L 27/04 - Raccords universels, c.-à-d. avec une liaison mécanique permettant un mouvement angulaire ou un réglage des axes des parties raccordées dans une direction quelconque avec surfaces de contact partiellement sphériques
F16L 37/084 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique
F16L 37/10 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage utilisant sur une partie un manchon ou segment externe rotatif
F16L 37/22 - Accouplements du type à action rapide dans lesquels l'assemblage est maintenu par des billes, rouleaux ou ressorts hélicoïdaux sous pression radiale entre parties
F16L 37/50 - Accouplements du type à action rapide réglablesAccouplements du type à action rapide permettant un déplacement des parties raccordées
A connector for use with a dialyzer to connect a conduit from a dialyzer with a conduit from a dialysate source. The connector includes a sleeve (female component) and a collet (male component). The sleeve has a generally cylindrical shape with an opening at one end having a circular shape with at least one slot positioned along the periphery of the circular shape. The sleeve also includes at least one flexible finger having a barb at a free end. The collet is configured to be housed within an interior chamber of the sleeve and has first and second gaps to house the barbs and first and second deflectable flanges to lock into recesses in a conduit.
A61M 1/26 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes en mouvement
F16L 27/04 - Raccords universels, c.-à-d. avec une liaison mécanique permettant un mouvement angulaire ou un réglage des axes des parties raccordées dans une direction quelconque avec surfaces de contact partiellement sphériques
F16L 37/084 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique
F16L 37/10 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage utilisant sur une partie un manchon ou segment externe rotatif
F16L 37/22 - Accouplements du type à action rapide dans lesquels l'assemblage est maintenu par des billes, rouleaux ou ressorts hélicoïdaux sous pression radiale entre parties
F16L 37/50 - Accouplements du type à action rapide réglablesAccouplements du type à action rapide permettant un déplacement des parties raccordées
A portable hemodialysis systern is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hernodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is rneasured by a preferred level sensor having a lever arrn, a load cell, and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate rneasurernents of the load cell caused by the tilt.
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient, to the dialyzer, and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. The hemodialysis system includes a hemodialysis machine and dialysate generator which are physically connectable to, and disconnectable from, one another. To connect the hemodialysis machine and dialysate generator together, both the hemodialysis machine and dialysate generator possess connectable and disconnectable electrical connectors and fluid connectors which are positioned and constructed to allow both a fluid and electrical connection between the two machines. The hemodialysis machine includes a processor and a user interface, preferably in the form of a touchscreen, that is capable of controlling both the functions of the hemodialysis machine and the dialysate generator.
A syringe pump to deliver heparin to into the blood circuit of a hemodialysis system. The syringe pump is configured to receive a syringe having a plunger movable within a lumen of an elongate tubular member. The syringe pump may include a housing having a recess configured to receive at least a portion of the syringe, a drive mechanism for moving the plunger within the lumen, the drive mechanism comprising a motor and a lead screw; and a grabber mechanism. The grabber mechanism includes a control arm, back panel, and upper and lower control fingers, the control fingers each have first and second ends, and a curved portion therebetween having a width, an interior edge, and an exterior edge, wherein the first ends of the upper and lower control fingers are coupled to the control arm via first and second spring hinges.
Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
B01D 61/00 - Procédés de séparation utilisant des membranes semi-perméables, p. ex. dialyse, osmose ou ultrafiltrationAppareils, accessoires ou opérations auxiliaires, spécialement adaptés à cet effet
F16L 21/08 - Raccords avec manchon ou douille avec moyens additionnels de verrouillage
F16L 37/14 - Raccords par insertion d'un élément entre surfaces à unir, p. ex. par un bout de fil, une goupille, une chaîne
F16L 37/08 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage
A connector for use with a dialyzer to connect a conduit from a dialyzer with a conduit from a dialysate source. The connector includes a sleeve (female component) and a collet (male component). The sleeve has a generally cylindrical shape with an opening at one end having a circular shape with at least one slot positioned along the periphery of the circular shape. The sleeve also includes at least one flexible finger having a barb at a free end. The collet is configured to be housed within an interior chamber of the sleeve and has first and second gaps to house the barbs and first and second deflectable flanges to lock into recesses in a conduit.
F16L 37/098 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique au moyen de crochets flexibles
F16L 37/138 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage utilisant des crochets, cliquet, ou autres organes de blocage mobiles ou que l'on peut insérer utilisant un manchon mobile axialement
F16L 13/16 - Raccords de tuyaux non démontables, p. ex. raccords soudés, collés ou matés réalisés par déformation plastique du matériau du tuyau, p. ex. par déformation des brides, par laminage le raccord consistant en des extrémités se superposant et munies de collets en prise les uns avec les autres
F16L 37/133 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage utilisant des crochets, cliquet, ou autres organes de blocage mobiles ou que l'on peut insérer utilisant des crochets flexibles
F16L 33/22 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches avec moyens non mentionnés dans les groupes précédents pour saisir la manche entre l'extérieur et l'intérieur
F16L 13/14 - Raccords de tuyaux non démontables, p. ex. raccords soudés, collés ou matés réalisés par déformation plastique du matériau du tuyau, p. ex. par déformation des brides, par laminage
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is measured by a preferred level sensor having a lever arm, a load cell, and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate measurements of the load cell caused by the tilt.
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient, to the dialyzer, and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. The hemodialysis system includes a hemodialysis machine and dialysate generator which are physically connectable to, and disconnectable from, one another. To connect the hemodialysis machine and dialysate generator together, both the hemodialysis machine and dialysate generator possess connectable and disconnectable electrical connectors and fluid connectors which are positioned and constructed to allow both a fluid and electrical connection between the two machines. The hemodialysis machine includes a processor and a user interface, preferably in the form of a touchscreen, that is capable of controlling both the functions of the hemodialysis machine and the dialysate generator.
Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.
A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
A61M 1/14 - Systèmes de dialyseReins artificielsOxygénateurs du sang
A61M 1/26 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes en mouvement
A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p. ex. adaptation de la température, irradiation
A61M 60/109 - Pompes extracorporelles, c.-à-d. que le sang est pompé à l’extérieur du corps du patient incorporées dans des circuits ou des systèmes sanguins extracorporels
A61M 60/279 - Pompes péristaltiques, p. ex. pompes à rouleau
A61M 60/37 - Hémodialyse, hémofiltration ou diafiltration
A61M 60/438 - Détails concernant l’entraînement pour les pompes pour le sang à déplacement positif la force agissant sur l’élément en contact avec le sang étant mécanique
A61M 60/835 - Détails structurels autres que ceux relatifs à l’entraînement de la pompe dans les pompes pour le sang à déplacement positif
A61M 60/847 - Détails structurels autres que ceux relatifs à l’entraînement de la pompe des pompes pour le sang extracorporelles disposés dans une cassette
CA 03108699 2021-02-03 ABSTRACT A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The hemodialysis system may include a sorbent filter in the dialysate flow path which filters used dialysate. Alternatively, the filter may be positioned within a separate closed loop filter flow path which is isolated from the blood flow path and dialysate flow path. For this embodiment, the hemodialysis system includes additional controllable fluid valves which selectively connect the filter flow path to the reservoir which is not currently providing dialysis treatment to a patient. Date recue/Date Received 2021-02-03
A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
A61M 60/109 - Pompes extracorporelles, c.-à-d. que le sang est pompé à l’extérieur du corps du patient incorporées dans des circuits ou des systèmes sanguins extracorporels
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The hemodialysis system may include a sorbent filter in the dialysate flow path which filters used dialysate. Alternatively, the filter may be positioned within a separate closed loop filter flow path which is isolated from the blood flow path and dialysate flow path. For this embodiment, the hemodialysis system includes additional controllable fluid valves which selectively connect the filter flow path to the reservoir which is not currently providing dialysis treatment to a patient.
A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The hemodialysis system may include a sorbent filter in the dialysate flow path which filters used dialysate. Alternatively, the filter may be positioned within a separate closed loop filter flow path which is isolated from the blood flow path and dialysate flow path. For this embodiment, the hemodialysis system includes additional controllable fluid valves which selectively connect the filter flow path to the reservoir which is not currently providing dialysis treatment to a patient.
The hemodialysis system includes a closed loop dialysate flow path which includes a dialyzer and a reservoir for storing dialysate, and a closed loop blood flow path which passes through the dialyzer in the opposite direction as the dialysate flow path. In addition, the hemodialysis system includes pumps for pumping dialysate and blood through their respective flow paths, a flow sensor for measuring the flow rate of dialysate in the dialysate flow path, and a level sensor for measuring the level of dialysate in the dialysate reservoir. A processor is connected to the flow sensor, reservoir level sensor and pumps to provide a first closed loop control system including the processor, flow sensor and a first dialysate pump, and a second closed loop control system including the processor, level sensor and a second dialysate pump which enable the processor to initiate, monitor and maintain ultrafiltration.
A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialyzer, and a dialysate flow path and a blood flow path which flow in opposing directions through the dialyzer. The disposable cartridge includes pressure and fluid flow sensors for measuring the pressure and fluid flow in the dialysate flow path and blood flow path. In addition, the disposable cartridge possesses pump actuators (but not pump motors) for pumping dialysate and blood through their respective flow paths. Preferably, the disposable cartridge includes a filter for removing waste products from dialysate.
A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialyzer, and a dialysate flow path and a blood flow path which flow in opposing directions through the dialyzer. The disposable cartridge includes pressure and fluid flow sensors for measuring the pressure and fluid flow in the dialysate flow path and blood flow path. In addition, the disposable cartridge possesses pump actuators (but not pump motors) for pumping dialysate and blood through their respective flow paths. Preferably, the disposable cartridge includes a filter for removing waste products from dialysate.
A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge further includes a filter for removing waste products from the dialysate as well as one or more flow sensors for measuring the flow of dialysate in the dialysate flow path. The preferred flow sensor includes a rotatable spoked wheel in the dialysate flow path which is rotated by the flow of dialysate. The spoked wheel includes one or more magnets which are rotated with the rotation of the spoked wheel. The flow sensor further includes a magnetic field sensor in the reused dialysis machine which is connected to a processor for monitoring the rotation of the spoked wheel to determine flow of fluid in the dialysate flow path.
A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge includes a filter for removing waste products from the dialysate, and pressure and fluid flow sensors for measuring the pressure and fluid flow in the dialysate flow path and blood flow path. Preferably, the filter has a vapor membrane for releasing gases including ammonia, but not liquids such as the dialysate. The reused dialysis machine possesses a reservoir for dialysate, an ammonia sensor adjacent to the vapor membrane, a level sensor, a blood leak sensor, a venous blood line pressure sensor, a venous blood line bubble detector, pump motors, and a processor connected to the motors and sensors for controlling and monitoring hemodialysis treatment.
A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge includes a filter for removing waste products from the dialysate. The reused dialysis machine possesses a reservoir for dialysate, various sensors including a reservoir level sensor assembly, and a processor connected to the various sensors for controlling and monitoring hemodialysis treatment. The reservoir level sensor assembly includes a vertically extending electrode array for transmitting electrical signals to the processor detecting whether the reservoir possesses sufficient dialysate for therapy, and for detecting whether there is a fault condition during therapy such as a loss of dialysate in the reservoir or an increase in fluid in the reservoir which may indicate a failure in the dialysis membrane.
A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge further includes a filter for removing waste products from the dialysate as well as one or more flow sensors for measuring the flow of dialysate in the dialysate flow path. The preferred flow sensor includes a rotatable spoked wheel in the dialysate flow path which is rotated by the flow of dialysate. The spoked wheel includes one or more magnets which are rotated with the rotation of the spoked wheel. The flow sensor further includes a magnetic field sensor in the reused dialysis machine which is connected to a processor for monitoring the rotation of the spoked wheel to determine flow of fluid in the dialysate flow path.
A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge includes a filter for removing waste products from the dialysate. The reused dialysis machine possesses a reservoir for dialysate, various sensors including a blood leak sensor assembly, and a processor connected to the various sensors for controlling and monitoring hemodialysis treatment. The blood leak sensor assembly includes a light source for emitting light through the dialysate flow path and a light sensor for receiving light having passed through the dialysate flow path. The processor is connected to the light source for determining whether blood has leaked from the blood flow path into the dialysate flow path. Preferably, the light source emits light having two peak wavelengths.
A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialyzer, and a dialysate flow path and a blood flow path which flow in opposing directions through the dialyzer. The disposable cartridge includes a filter for removing waste products from the dialysate, and pressure and fluid flow sensors for measuring the pressure and fluid flow in the dialysate flow path and blood flow path. In addition, the disposable cartridge possesses pump actuators (but not pump motors) for pumping dialysate and blood through their respective flow paths. The reused dialysis machine possesses a reservoir for dialysate, a level sensor, a blood leak sensor, an ammonia sensor, a venous blood line pressure sensor, a venous blood line bubble detector, pump motors, and a processor connected to the motors and sensors for controlling and monitoring hemodialysis treatment.
A portable hemodialysis system is provided suitable for in home use. The hemodialysis system includes a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialyzer, and a dialysate flow path and a blood flow path which flow in opposing directions through the dialyzer. In addition, the disposable cartridge possesses pump actuators (but not pump motors) for pumping dialysate and blood through their respective flow paths. The pump actuators having non-deformable components including a housing having a central cavity forming an internal sidewall, a rotor eccentrically positioned within the cavity having radially aligned slots at the rotor's periphery, and vanes slideably positioned in the slots to slide in and out of the slots so as to seal with the cavity's internal sidewall creating vane chambers that pump blood or dialysate.
