|
|
Résultats pour
brevets
1.
|
LOW ANTICOAGULANT HEPARINS
| Numéro d'application |
SE2011051538 |
| Numéro de publication |
2013/095215 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2011-12-19 |
| Date de publication |
2013-06-27 |
| Propriétaire |
DILAFORETTE AB (Suède)
|
| Inventeur(s) |
- Ekre, Hans-Peter
- Eriksson, Per-Olov
- Leitgeb, Anna
- Wahlgren, Mats
- Pikas, Dagmar
- Lindahl, Ulf
- Holmer, Erik
|
Abrégé
The present invention relates to chemically modified sulfated glycosaminoglycan derivatives selected from the group of heparin, heparan sulfate, dermatan sulfate and chondroitin sulphate with an antifactor II activity of less than 10 IU/mg, an antifactor Xa activity of less than 10 IU/mg and an average molecular weight (Mw) between about 6.5 and 9.5 kDa. Also disclosed is a method of preparing the derivatives and their medical uses, including treatment of malaria and treatment of vaso-occlusive crisis in sickle cell disease.
|
2.
|
LOW ANTICOAGULANT HEPARINS
| Numéro d'application |
SE2012051428 |
| Numéro de publication |
2013/095276 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2012-12-19 |
| Date de publication |
2013-06-27 |
| Propriétaire |
DILAFORETTE AB (Suède)
|
| Inventeur(s) |
- Ekre, Hans-Peter
- Lindahl, Ulf
- Holmer, Erik
- Eriksson, Per-Olov
- Leitgeb, Anna
- Wahlgren, Mats
- Tidia, Stefania
- Liverani, Lino
|
Abrégé
The present invention relates to a chemically modified heparin, with an antifactor II activity of less than 10 IU/mg, an antifactor Xa activity of less than 10 IU/mg and an average molecular weight (Mw) between about 6.5 and 9.5 kDa. Also disclosed is a method of preparing the heparin and its medical use, including treatment of malaria.
|
3.
|
USE OF CHEMICALLY MODIFIED HEPARIN DERIVATES IN SICKLE CELL DISEASE
| Numéro d'application |
SE2012051429 |
| Numéro de publication |
2013/095277 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2012-12-19 |
| Date de publication |
2013-06-27 |
| Propriétaire |
DILAFORETTE AB (Suède)
|
| Inventeur(s) |
- Ekre, Hans-Peter
- Leitgeb, Anna
- Wahlgren, Mats
- Pikas, Dagmar
|
Abrégé
The present invention relates to chemically modified heparin for use in the treatment of sickle cell disease, with an antifactor II activity of less than 10 IU/mg, an antifactor Xa activity of less than 10 IU/mg and an average molecular weight (Mw) between about 6.5 and 9.5 kDa.
Classes IPC ?
- C08B 37/10 - HéparineSes dérivés
- A61K 31/727 - HéparineHéparane
- A61P 7/00 - Médicaments pour le traitement des troubles du sang ou du fluide extracellulaire
|
|