An apparatus and method for inline detection and modification of suboptimal scan views of a plurality of consecutive images. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive the plurality of consecutive images from at least an imaging device, wherein each consecutive image of the plurality of consecutive images is associated with at least an image metric, detect a first consecutive image and a second consecutive image that are out of specification, wherein the second consecutive image is suboptimal, modify the one or more metrics as a function of the probed focal plane, and initiate a rescanning operation of the second consecutive image as a function of the probed focal plane.
An apparatus and method for rescan workflow management in automated scanning systems are disclosed. The apparatus includes a scanning system configured to initiate a scanning and rescanning operation for at least a slide, at least a processor and a memory containing instructions configuring the at least a processor to receive at least a scanned image, determine a quality metric of the at least a scanned image using at least a quality control algorithm, determine a quality error by comparing the quality metric to a quality threshold, receive, as a function of determining the quality error, a user input for the at least a scanned image, digitally map the user input to at least a corresponding region on the at least a slide, generate a scanner command as a function of the at least a corresponding region and transmit the scanner command to the scanning system.
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06V 10/776 - ValidationÉvaluation des performances
G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 70/20 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pratiques ou des directives
G02B 21/34 - Lames de microscope, p. ex. montage d'échantillons sur des lames de microscope
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
3.
APPARATUS AND METHOD FOR RESCAN WORKFLOW MANAGEMENT IN AUTOMATED SCANNING SYSTEMS
An apparatus and method for rescan workflow management in automated scanning systems are disclosed. The apparatus includes a scanning system configured to initiate a scanning and rescanning operation for at least a slide, at least a processor and a memory containing instructions configuring the at least a processor to receive at least a scanned image, determine a quality metric of the at least a scanned image using at least a quality control algorithm, determine a quality error by comparing the quality metric to a quality threshold, receive, as a function of determining the quality error, a user input for the at least a scanned image, digitally map the user input to at least a corresponding region on the at least a slide, generate a scanner command as a function of the at least a corresponding region and transmit the scanner command to the scanning system.
A system for optimizing slide pick basket operations, wherein the system includes at least a processor and a non-transitory memory communicatively connected to the at least a processor, wherein the non-transitory memory contains instructions configuring the at least a processor to receive visual data from a sensor, determine an orientation of a first slide of a plurality of slides within a pick basket as a function of the visual data and a system requirement, and perform a first operation on the first slide within the pick basket as a function of determining the orientation of the first slide.
G06K 7/10 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire
5.
SYSTEMS AND METHODS FOR AUGMENTED VISUALIZATION USING ACTIVITY WINDOWS
A system for augmented visualization using activity windows includes a processor and a memory containing instructions that configure the processor. The processor is configured to receive image data, generate a display data structure with an activity window, and instantiate artificial intelligence (AI) agents within the activity window. The system receives user input associated with the image data and executes the AI agents to retrieve external data and generate agent outputs based on the external data and image data. The display data structure is updated by modifying the activity window as a function of the agent outputs.
G06F 3/0481 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] fondées sur des propriétés spécifiques de l’objet d’interaction affiché ou sur un environnement basé sur les métaphores, p. ex. interaction avec des éléments du bureau telles les fenêtres ou les icônes, ou avec l’aide d’un curseur changeant de comportement ou d’aspect
6.
APPARATUS AND METHOD FOR AUTOMATICALLY VALIDATING QUALITY DATA ASSOCIATED WITH AT LEAST A SLIDE
An apparatus and method for automatically validating quality data associated with at least a slide. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive, from the at least an optical device, at least a digital slide corresponding to the at least a slide, determine, using metadata, a slide identification, localize, using at least an object detection technique, the at least a digital slide, wherein localizing the at least a digital slide comprises identifying a stained core of interest and aligning the stained core of interest into a standard form, and, evaluate, using a predefined threshold, the stained core of interest, wherein evaluating comprises comparing the stained core of interest to a control core, generating a validation output, and transmitting the validation output to a downstream device.
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06V 10/24 - Alignement, centrage, détection de l’orientation ou correction de l’image
G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
7.
SYSTEMS AND METHODS FOR INLINE QUALITY CONTROL OF SLIDE DIGITIZATION
Described herein is a system for digitizing a slide. A system may include an optical system comprising at least an optical sensor and at least a processor communicatively connected to the optical system, wherein the at least a processor is configured to perform a scan of a slide by capturing at least a first image according to a first scanning parameter, determine, using a localization module, a localization quality metric as a function of the at least a first image, identify, using the localization module and the localization quality metric, at least one region of interest of the slide, determine a second scanning parameter as a function of the localization quality metric, capture, using the optical system, at least a second image of the slide according to the second scanning parameter, and generate a map comprising values associated with locations of the slide comprising a biological sample.
An apparatus for generating a confidence score associated with a scanned label is disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a profile, wherein the profile includes at least a label and a plurality of digital representations of slides, perform a flip detection process on the profile to verify the orientation of at least slide data of the profile, generate a scanned label as a function of the at least a label, determine a confidence score associated with the scanned label, adjust the confidence score for accuracy, and display the confidence score using a display device.
G06K 7/14 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire utilisant la lumière sans sélection des longueurs d'onde, p. ex. lecture de la lumière blanche réfléchie
9.
Systems and methods for automated profile identification
A system including at least an imaging device and a computing device configured to control the at least an imaging device while pre-scanning the target, receive, from the at least an imaging device, the pre-scan imaging data, detect a position of the fiducial marker within the pre-scan imaging data, input the pre-scan imaging data into a feature-learning neural network, output at least an image feature from the feature-learning neural network as a function of the pre-scan imaging data, wherein the at least a feature represents at least a specimen type, selecting a target profile as a function of the specimen type and the fiducial marker, wherein the target profile includes one or more imaging parameters and adjust, using the target profile, one or more imaging device parameters as a function of the one or more imaging parameters.
H04N 23/60 - Commande des caméras ou des modules de caméras
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 20/62 - Texte, p. ex. plaques d’immatriculation, textes superposés ou légendes des images de télévision
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p. ex. pour planifier la maintenance ou les mises à jour
H04N 23/667 - Changement de mode de fonctionnement de la caméra, p. ex. entre les modes photo et vidéo, sport et normal ou haute et basse résolutions
10.
System and method for automated optical deviation detection and correction procedure
A system and method for automated optical deviation detection and correction is disclosed. The system includes a scanner, wherein the scanner includes one or more sensors positioned on the scanner, wherein the one or more sensors includes at least an optical sensor and a force-torque sensor; and a stage configured to hold a slide; at least a processor; and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring processor to: receive sensor data from the one or more sensors, wherein the sensor data includes image data received from the optical sensor and associated with at least a slide and a tactile datum; detect a positional deviation in the image data relative to an alignment baseline; determine whether the positional deviation is within a correction threshold; and initiate a correction procedure associated with the at least a slide.
G01B 5/25 - Dispositions pour la mesure caractérisées par l'utilisation de techniques mécaniques pour mesurer des angles ou des cônesDispositions pour la mesure caractérisées par l'utilisation de techniques mécaniques pour tester l'alignement des axes pour tester l'alignement des axes
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
11.
APPARATUS AND METHOD FOR ADAPTIVE HANDLING OF SLIDES USING A ROBOTIC ARM
An apparatus and method for adaptive handling of slides using a robot arm. The apparatus includes at least a computing device comprised of a processor and a memory communicatively connected to the processor. The memory instructs the processor to receive a calibration procedure, wherein the calibration procedure is generated using a plurality of waypoints. The processor controls the at least a robotic arm as a function of the calibration procedure, wherein the calibration procedure is configured to cause the robotic arm to pick, using a pick waypoint of the plurality of waypoints, and place, using a place waypoint of the plurality of waypoints, a slide. The processor receives a plurality of feedback from the at least a robotic arm. The processor generates, using the plurality of feedback, an adapted pick waypoint. The memory instructs the processor to generate, using the plurality of feedback, an adapted place waypoint.
An apparatus and method for control of rescanning a slide in a graphical user interface. The apparatus includes at least a processor and a memory communicatively connected to the processor configured to receive a first virtual slide from a scanning device, generate a display data structure, wherein generating the display data structure further comprises providing a plurality of visual elements associated with a plurality of events and at least an event handler, wherein a first visual element of the plurality of visual elements is associated with a first event of the plurality of events, a second visual element of the plurality of visual elements is associated with a second event comprising user input, and the second event configured to trigger a rescanning operation as a function of the user input, and display the first virtual slide.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
A modular data acquisition and analysis system may include at least a processor and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to receive, from a module database, a library of interoperable modules, receive, from a user interface, a module selection, generate an interface, receive a user input through the interface, update the interface as a function of the user input, define a customized workflow as a function of the user input, and save the customized workflow for subsequent execution.
A system for microscopy slide locking include a stage slot configured to fit a microscopy slide, the stage slot including a first corner and a second corner diagonally across the first corner, a static securing element disposed at the first corner and configured to contact a microscopy slide at a first pair of its orthogonal, intersecting edges, and a dynamic securing element disposed at the second corner and configured to contact the microscopy slide at a second pair of its orthogonal, intersecting edges diagonally opposite the first pair of its orthogonal, intersecting edges, wherein the dynamic securing element includes a translating portion configured to slide in a translational direction between a proximal position and a distal position and a rotating portion rotationally connected to the translating portion and configured to rotate around an axis of rotation normal to a face of the microscopy slide and the translational direction.
An apparatus and method for adaptive slide imaging using a selected scanning profile is disclosed. The apparatus includes a scanner configured to capture a macro image of a slide and including a stage configured to hold the slide, an optical sensor configured to convert an image into one or more electrical signals, and an optical system configured to form the image of the slide on the optical sensor. The apparatus includes at least a processor and a memory containing instructions configuring the at least a processor to receive the macro image of the slide from the scanner, extract metadata from the macro image of the slide, determine a classification category of the slide, retrieve a scanning profile as a function of the classification category of the slide, and image, using the optical system and optical sensor of the scanner, the slide as a function of the scanning profile.
An apparatus an method for generating three-dimensional representations of serial sections, wherein the method includes creating a plurality of slide images using a slide scanner, the slide scanner comprising an image sensor and a stage, receiving, using at least a processor, the plurality of slide images from the slide scanner, extracting, using the at least a processor, a plurality of features from the plurality of serial slide section images using a feature extraction algorithm, registering, using the at least a processor, the plurality of serial slide section images as a function of the plurality of feature, generating, using the at least a processor, a three-dimensional (3D) stack view, wherein the 3D stack view comprises the plurality of serial slide section images, and displaying the 3D stack view through a display device.
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06T 7/62 - Analyse des attributs géométriques de la superficie, du périmètre, du diamètre ou du volume
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
17.
Apparatus and method for automatic calibration of a robotic arm in a modular system
An apparatus and method for automatic calibration of a robotic arm in a modular system. The apparatus includes at least a cluster configuration, at least a computing device comprising a memory and a processor, communicatively connected to the memory, wherein the processor is configured to receive a cluster configuration input, identify at least a calibration parameter, capture a coarse pose, transmit a first waypoint sequence to at least a modular component, modify the coarse pose of at least a configurable waypoint in the waypoint template, transmit a second waypoint sequence, and display, using a display device, an output.
An apparatus and method for automatically validating quality data associated with at least a slide. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive, from the at least an optical device, at least a digital slide corresponding to the at least a slide, determine, using metadata, a slide identification, localize, using at least an object detection technique, the at least a digital slide, wherein localizing the at least a digital slide comprises identifying a stained core of interest and aligning the stained core of interest into a standard form, and, evaluate, using a predefined threshold, the stained core of interest, wherein evaluating comprises comparing the stained core of interest to a control core, generating a validation output, and transmitting the validation output to a downstream device.
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06V 10/24 - Alignement, centrage, détection de l’orientation ou correction de l’image
G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
19.
Apparatus and method for generating a modified composite view as a function of a plurality of whole slide images and a reconstruction model
An apparatus and method for generating a modified composite view as a function of a plurality of whole slide images and a reconstruction model. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor configured to receive a plurality of whole slide images, register the plurality of whole slide images based on one or more features of at least a structure by identifying, at least a structural continuation in the first image and the second image, and adjusting the first image with respect to the second image, generate an initial composite view by positioning the plurality of whole slide images into the initial composite view based on the at least a structural continuation of the one or more features of the at least a structure, and display the initial composite view.
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06V 10/74 - Appariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
20.
APPARATUS AND METHOD FOR DETECTING CONTENT OF INTEREST ON A SLIDE USING MACHINE LEARNING
An exemplary apparatus according to this disclosure includes at least a display, a processor, and a memory communicatively connected to the processor. The processor generates a display data structure comprising a plurality of visual elements, configures a display device to display the visual elements, receives an activation of an event handler of the plurality of event handlers, wherein receiving the activation further comprises receiving a user selection of a visual element of the plurality of visual elements that is linked to the event handler, and executes the algorithm module associated with the activated event handler comprising an image processing module configured to receive an initial image and output a modified image.
G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
21.
APPARATUS AND METHOD FOR DETECTING CONTENT OF INTEREST ON A SLIDE USING MACHINE LEARNING
An apparatus and method for detecting content of interest on a slide using machine learning. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a first image, comprising a macro image, identify areas of interest associated with the grids of the first image, receive a second image comprising a high magnification image associated with the areas of interest of the first image, classify, using at least a probed point, the grids of the first image, wherein classifying the grids of the first image includes classifying the grids into accepted grids of the grids and rejected grids of the grids, scan, using the image capturing device, the accepted grids to generate an output image, and display, using a display device, the output image.
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
22.
APPARATUS AND METHOD FOR AUTOMATED MICRODISSECTION OF TISSUE FROM SLIDES TO OPTIMIZE TISSUE HARVEST FROM REGIONS OF INTEREST
An apparatus and method for automated microdissection of tissue from slides to optimize tissue harvest from regions of interest are disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to receive a stained input slide, identify a region of interest on the stained input slide, generate a segmentation map of the region of interest as a function of a segmentation algorithm, register a segmented region of interest, as a function of the segmentation map, onto an unstained slide, wherein registering the segmented region of interest includes determining an orientation of the unstained slide corresponding to the segmented region of interest of the stained input slide, recording the orientation of the unstained slide relative to a reference plane, and registering the segmented region of interest to the unstained slide.
G01N 1/28 - Préparation d'échantillons pour l'analyse
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
Systems for augmented visualization using activity windows may include at least a processor, a memory communicatively connected to the at least a processor and an interactive display device. The memory may store instructions configuring the processor to initiate a method for image processing and labeling for user display. A method for augmented visualization using activity windows may include receiving image data from an imaging device, executing at least a first algorithm on the image data, wherein the first algorithm is configured to output annotation data associated with the image data, generating a display data structure, and displaying the display data structure at interactive display device.
G06V 10/94 - Architectures logicielles ou matérielles spécialement adaptées à la compréhension d’images ou de vidéos
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G06V 20/70 - Étiquetage du contenu de scène, p. ex. en tirant des représentations syntaxiques ou sémantiques
G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
24.
SYSTEMS AND METHODS FOR AUGMENTED VISUALIZATION USING ACTIVITY WINDOWS
Systems for augmented visualization using activity windows may include at least a processor, a memory communicatively connected to the at least a processor and an interactive display device. The memory may store instructions configuring the processor to initiate a method for image processing and labeling for user display. A method for augmented visualization using activity windows may include receiving image data from an imaging device, executing at least a first algorithm on the image data, wherein the first algorithm is configured to output annotation data associated with the image data, generating a display data structure, and displaying the display data structure at interactive display device.
A system for optimizing slide pick basket operations, wherein the system includes at least a robotic arm, at least a processor, and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to perform an orientation check on a plurality of slides in a pick basket, wherein performing an orientation check includes receiving visual data, identifying an orientation of a first slide of the plurality of slides as a function of the visual data, and verifying that the orientation of the first slide aligns with a system requirement, pick the first slide of the plurality of slides as a function of verifying that the orientation of the first slide aligns with the system requirement, and place the first slide at a scanner.
G06K 7/10 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire
26.
System and method for automated calibration for a scanning system
An automated resolution and sharpness calibration system for target scanning includes an imaging reference located on a scanner's scanning stage and an optical sensor configured to capture reference images before and after scanning a target. The system comprises a processor and a memory with instructions that enable the processor to receive the captured reference images, determine image metrics based on reference features, and detect deviations in these metrics between the images. The processor classifies the detected deviation to identify its cause and generates an alert signal accordingly. This system ensures precise calibration by analyzing deviations in image metrics, thereby maintaining optimal scanning performance and accuracy.
An exemplary apparatus according to this disclosure includes at least a display, a processor, and a memory communicatively connected to the processor. The processor generates a display data structure comprising a plurality of visual elements, configures a display device to display the visual elements, receives an activation of an event handler of the plurality of event handlers, wherein receiving the activation further comprises receiving a user selection of a visual element of the plurality of visual elements that is linked to the event handler, and executes the algorithm module associated with the activated event handler comprising an image processing module configured to receive an initial image and output a modified image.
G06F 3/04845 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p. ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs pour la transformation d’images, p. ex. glissement, rotation, agrandissement ou changement de couleur
G06F 3/0481 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] fondées sur des propriétés spécifiques de l’objet d’interaction affiché ou sur un environnement basé sur les métaphores, p. ex. interaction avec des éléments du bureau telles les fenêtres ou les icônes, ou avec l’aide d’un curseur changeant de comportement ou d’aspect
A method for on-demand registration of whole slide images (WSIs), comprising receiving at least two digital images, a first digital image of a reference slide and a second digital image on a candidate slide, each at a first magnification level, identifying a first region of interest (ROI) on the first digital image at a target magnification level, registering a portion of the second digital image to a portion of the first digital slide image at the first magnification level to derive a transformation matrix, applying the transformation matrix to the first ROI to identify a second ROI on the second digital image at the first magnification level, mapping the second ROI to a corresponding second ROI on the second digital image at the target magnification level, and registering the corresponding second ROI to the first ROI at the target magnification level.
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06T 7/37 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés de transformation de domaine
29.
APPARATUS FOR CONTROL OF IMAGE PROCESSING ALGORITHMS IN A GRAPHICAL INTERFACE
An exemplary apparatus according to this disclosure includes at least a display, a processor, and a memory communicatively connected to the processor. The processor generates a display data structure comprising a plurality of visual elements, configures a display device to display the visual elements, receives an activation of an event handler of the plurality of event handlers, wherein receiving the activation further comprises receiving a user selection of a visual element of the plurality of visual elements that is linked to the event handler, and executes the algorithm module associated with the activated event handler comprising an image processing module configured to receive an initial image and output a modified image.
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c.-à-d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
30.
Apparatus and method for feedback utilization in automated scanning systems
An apparatus for feedback utilization in automated scanning systems, the apparatus including a scanning system and a computing device configured to extract a unique identifier from the slide label located on the at least a slide using the scanning system, retrieve a user input associated with the at least a slide, digitally map the user input to at least a corresponding region on the at least a slide generate at least one scanner command as a function of the transformed user input wherein the at least one scanner command is configured to command the scanning system to prioritize the transformed user input when rescanning the at least a slide and transmit the at least one scanner command to the scanning system to generate the at least a re-scanned image.
G06V 10/98 - Détection ou correction d’erreurs, p. ex. en effectuant une deuxième exploration du motif ou par intervention humaineÉvaluation de la qualité des motifs acquis
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
31.
Apparatus and method for rescan workflow management in automated scanning systems
An apparatus and method for rescan workflow management in automated scanning systems are disclosed. The apparatus includes a scanning system configured to initiate a scanning and rescanning operation for at least a slide, at least a processor and a memory containing instructions configuring the at least a processor to receive at least a scanned image, determine a quality metric of the at least a scanned image using at least a quality control algorithm, determine a quality error by comparing the quality metric to a quality threshold, receive, as a function of determining the quality error, a user input for the at least a scanned image, digitally map the user input to at least a corresponding region on the at least a slide, generate a scanner command as a function of the at least a corresponding region and transmit the scanner command to the scanning system.
Aspects of present disclosure relate to slide imaging. An exemplary system for imaging a slide includes at least an optical system, including an optical sensor; a slide port configured to hold a slide; and a first computing device configured to: capture, using the at least an optical system, a plurality of images of the slide, including a first image; automatically select an algorithm to apply to the first image; identify a control command as a function of the first image; and capture, using the at least an optical system, a second image of the plurality of images as a function of the control command.
A system for imaging a slide, the system including a slide port configured to receive a slide, at least an optical system, wherein the at least an optical system includes at least an optical sensor configured to capture a first image of the received slide, and a first computing device configured to receive the first image from the at least an optical system, automatically select at least an algorithm to apply to the first image, identify a control command as a function of the selected algorithm upon execution of the selected algorithm and configure the at least an optical system to capture a second image of the slide at the slide port through the at least an optical sensor as a function of the control command.
An apparatus and method of hot-swapping a component of a component unit in a cluster. The apparatus includes a memory communicatively connected to at least a processor, the memory contains instructions configuring the at least a processor to receive quality control data from each functioning component of a component unit in at least a cluster, determine a degree of quality of each functioning component of the component unit in the at least a cluster as a function of the quality control data, determine a swappable component in the component unit of the at least a cluster as a function of the degree of quality and initiate a hot-swap procedure for the swappable component, wherein initiating the hot-swap procedure includes deregistering the swappable component from the component unit and registering a replacement component in place of the swappable component to the component unit.
A system for a slide marking technique for target tissue extraction and downstream application, the system including at least a marking device, wherein the at least a marking device is configured to image one or more unstained surfaces of a sample associated with a stained slide and mark a region of interest associated with the sample, at least a computing device including at least a processor and a memory, the computing device configured to, receive the images of the one or more unstained surfaces of the sample, receive a stained slide image of the sample, determine a geometric registration of the images of the one or more unstained surfaces of the sample to the stained slide image, determine the region of interest associated with the sample as a function of the geometric registration and provide the region of interest to the marking device.
An imaging device for image generation of a specimen is disclosed. Layers of images may be captured by an optical system and then compiled to create an integrated image. Each layer may include a different focal point. A consolidated image may then be created by combining one or more integrated images.
G06T 7/80 - Analyse des images capturées pour déterminer les paramètres de caméra intrinsèques ou extrinsèques, c.-à-d. étalonnage de caméra
H04N 23/69 - Commande de moyens permettant de modifier l'angle du champ de vision, p. ex. des objectifs de zoom optique ou un zoom électronique
H04N 23/695 - Commande de la direction de la caméra pour modifier le champ de vision, p. ex. par un panoramique, une inclinaison ou en fonction du suivi des objets
37.
Method and system for automated retrieval and scanning of glass slides within a restricted spatial environment
A system and method for automated slide retrieval and scanning is disclosed. The system comprises at least a processor configured to receive, from a user, a set of scan requirements, identify a current slide configuration, generate an operational scan sequence based on the received scan requirements and the current slide configuration, and execute the generated operational scan sequence.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G01N 21/01 - Dispositions ou appareils pour faciliter la recherche optique
G02B 21/34 - Lames de microscope, p. ex. montage d'échantillons sur des lames de microscope
An apparatus for imaging a slide, the apparatus including at least an optical system, including an optical sensor, a slide port configured to hold the slide, at least a processor, and a memory communicatively connected to the at least a processor, the memory containing instructions configuring the at least a processor to receive at least a region of interest, capture, using the at least an optical system, a plurality of first images of the slide at a first position within the at least a region of interest, wherein each of the plurality of first images has a different focus distance, and identify a focus pattern.
A system for detecting and cleaning contaminants from an imaging optical path, comprising an imaging device configured to receive a slide and capture a first slide image, at least a computing device configured to determine a contaminant presence indicator associated with a contaminant within an optical path of the imaging device based on the first slide image and execute a contaminant cleaning protocol as a function of the contaminant presence indicator, a contaminant removal mechanism configured to remove the contaminant from the optical path according to the contaminant cleaning protocol, wherein the computing device is further configured to re-evaluate the contaminant presence indicator based on a second slide image of the slide captured using the imaging device and request a user input upon a positive re-evaluation of the contaminant presence indicator.
An apparatus and method of use of a mechanism that converts rotary motion into linear motion are disclosed. The method includes mechanically connecting, using a first connecting component, a rotary component and one or more movable components, mechanically connecting, using a second connecting component, a plurality of gripping components and the one or more movable components, generating, using the rotary component, rotary motion about a rotational axis, transferring, using the first connecting component, the rotary motion to the one or more movable components, transferring, using the second connecting component, the off-axis motion of the one or more movable components to the plurality of gripping components and moving the plurality of gripping components linearly in opposite directions.
A system of digitalizing a slide, comprising at least one imaging device and a computing device communicatively connected to the imaging device, wherein the computing device is configured to scan each slide of a plurality of slides at the imaging device to generate an initial slide image and associated scanning metadata for each slide, determine a quality control metric for each slide as a function of the initial slide image and the associated scanning metadata, wherein determining the quality control metric includes flagging the slide based on the determined quality control metric, generate at least one scanning profile as a function of the scanning metadata based on the quality control metric, and re-scan the flagged slides at the imaging device using the at least one scanning profile.
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
42.
SYSTEMS AND METHODS FOR DIGITIZATION OF TISSUE SLIDES BASED ON ASSOCIATIONS AMONG SERIAL SECTIONS
The present disclosure describes an exemplary system and method for the digitization of tissue slides based on associations among serial sections. The system includes at least a computing device, wherein the computing device includes a memory and processor communicatively connected to one another, and a scanner, configured to scan a slide and send a digitized image of the slide to the computing device. A method for the digitization of tissue slides based on associations among serial sections may include receiving a candidate tissue map associated with a candidate tissue section, receiving a reference tissue map associated with a reference tissue section, aligning the candidate tissue map to the reference tissue map, comparing the aligned candidate tissue map to the reference tissue map, and generating a regenerated candidate tissue map as a function of the reference tissue map.
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
43.
APPARATUS AND METHOD FOR IDENTIFYING REGIONS OF INTEREST DURING SLIDE DIGITIZATION
An apparatus for identifying regions of interest during slide digitization is disclosed. The apparatus includes at least processor and a memory communicatively connected to the processor. The memory contains instructions configuring the processor to receive a user dataset associated with at least a pathology slide. The memory contains instructions configuring the processor to identify one or more regions of interest within at least a pathology slide as a function of the user dataset. The memory contains instructions configuring the processor to identify at least one scan parameter as a function of the one or more regions of interest. The memory contains instructions configuring the processor to generate a digitized slide by scanning the at least a pathology slide as a function the at least one scan parameter.
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 70/60 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pathologies
44.
SYSTEM AND METHOD FOR VISUALIZATION OF DIGITIZED SLIDES
A method for visualization of digitized slides is disclosed. The method comprises retrieving, using at least a processor, a digitized slide, determining, using the at least a processor, one or more visualization components of the digitized slide, generating, using the at least a processor, a virtual slide corresponding to the digitized slide based on the one or more visualization components, conditionally adjusting, using the at least a processor, a parameter of the virtual slide using one or more predefined temples, and displaying, using a user display, a visualization of the virtual slide.
An exemplary apparatus according to this disclosure includes at least a display, a processor, and a memory communicatively connected to the processor. The processor generates a display data structure comprising a plurality of visual elements, configures a display device to display the visual elements, receives an activation of an event handler of the plurality of event handlers, wherein receiving the activation further comprises receiving a user selection of a visual element of the plurality of visual elements that is linked to the event handler, and executes the algorithm module associated with the activated event handler comprising an image processing module configured to receive an initial image and output a modified image.
G06F 3/04845 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p. ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs pour la transformation d’images, p. ex. glissement, rotation, agrandissement ou changement de couleur
G06F 3/0481 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] fondées sur des propriétés spécifiques de l’objet d’interaction affiché ou sur un environnement basé sur les métaphores, p. ex. interaction avec des éléments du bureau telles les fenêtres ou les icônes, ou avec l’aide d’un curseur changeant de comportement ou d’aspect
A system for microscopy slide locking include a stage slot configured to fit a microscopy slide, the stage slot including a first corner and a second corner diagonally across the first corner, a static securing element disposed at the first corner and configured to contact a microscopy slide at a first pair of its orthogonal, intersecting edges, and a dynamic securing element disposed at the second corner and configured to contact the microscopy slide at a second pair of its orthogonal, intersecting edges diagonally opposite the first pair of its orthogonal, intersecting edges, wherein the dynamic securing element includes a translating portion configured to slide in a translational direction between a proximal position and a distal position and a rotating portion rotationally connected to the translating portion and configured to rotate around an axis of rotation normal to a face of the microscopy slide and the translational direction.
An apparatus for generating a confidence score associated with a scanned label is disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a profile, wherein the profile includes at least a label and a plurality of digital representations of slides, perform a flip detection process on the profile to verify the orientation of at least slide data of the profile, generate a scanned label as a function of the at least a label, determine a confidence score associated with the scanned label, adjust the confidence score for accuracy, and display the confidence score using a display device.
G06K 7/14 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire utilisant la lumière sans sélection des longueurs d'onde, p. ex. lecture de la lumière blanche réfléchie
48.
SYSTEM AND METHODS FOR COLOR GAMUT NORMALIZATION FOR PATHOLOGY SLIDES
A system for color gamut normalization for pathology slides, the system including at least computing device, wherein the computing device is configured to receive a whole slide image, generate a plurality of segments associated with the whole slide image as a function of one or more biological tissue type variabilities, apply a segment-specific transformation to each segment of the plurality of segments, create a user interface data structure, wherein the user interface data structure includes the plurality of segments and display the plurality of segments through a graphical user interface as a function of the user interface data structure.
An apparatus for visualization of digitized glass slides belonging to a patient case having a processor and a memory communicatively connected to the processor, the memory containing instructions configuring the processor to receive an image data set having a plurality of images of one or more specimens and metadata of the plurality of images of the one or more specimens, identify one or more constituent virtualization components for each image, determine a relationship between the one or more constituent visualization components as a function of the image data set, construct a plurality of virtual images as a function of the image data set and the relationship between the one or more virtual constituent components, wherein each of plurality of the images includes at least one virtual constituent component, generate a consolidated virtual image as a function of the plurality of virtual images and display the consolidated virtual image.
G06V 10/24 - Alignement, centrage, détection de l’orientation ou correction de l’image
G06V 10/74 - Appariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
50.
Apparatus and method for adaptive handling of slides using a robotic arm
An apparatus and method for adaptive handling of slides using a robot arm. The apparatus includes at least a computing device comprised of a processor and a memory communicatively connected to the processor. The memory instructs the processor to receive a calibration procedure, wherein the calibration procedure is generated using a plurality of waypoints. The processor controls the at least a robotic arm as a function of the calibration procedure, wherein the calibration procedure is configured to cause the robotic arm to pick, using a pick waypoint of the plurality of waypoints, and place, using a place waypoint of the plurality of waypoints, a slide. The processor receives a plurality of feedback from the at least a robotic arm. The processor generates, using the plurality of feedback, an adapted pick waypoint. The memory instructs the processor to generate, using the plurality of feedback, an adapted place waypoint.
An apparatus and method for detecting content of interest on a slide using machine learning. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a first image, comprising a macro image, identify areas of interest associated with the grids of the first image, receive a second image comprising a high magnification image associated with the areas of interest of the first image, classify, using at least a probed point, the grids of the first image, wherein classifying the grids of the first image includes classifying the grids into accepted grids of the grids and rejected grids of the grids, scan, using the image capturing device, the accepted grids to generate an output image, and display, using a display device, the output image.
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
52.
Imaging device and a method for image generation of a specimen
An imaging device for image generation of a specimen is disclosed. Layers of images may be captured by an optical system and then compiled to create an integrated image. Each layer may include a different focal point. A consolidated image may then be created by combining one or more integrated images.
H04N 23/695 - Commande de la direction de la caméra pour modifier le champ de vision, p. ex. par un panoramique, une inclinaison ou en fonction du suivi des objets
G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
Aspects of present disclosure relate to real-time image generation. An exemplary apparatus for real time image generation includes at least an optical system, a slide port configured to hold a slide, an actuator mechanism mechanically connected to a mobile element, a user interface comprising an input interface and an output interface, at least a processor configured to: using the at least an optical system, capture a first image of the slide at a first position, modify the first image, using the output interface, display the first image to a user, using the input interface, receive a parameter set from the user.
Aspects of present disclosure relate to real-time image generation. An exemplary apparatus for real time image generation includes at least an optical system, a slide port configured to hold a slide, an actuator mechanism mechanically connected to a mobile element, a user interface comprising an input interface and an output interface, at least processor configured to: using the at least an optical system, capture a first image of the slide at a first position, modify the first image, using the output interface, display the first image to a user, using the input interface, receive a parameter set from the user.
Aspects of present disclosure relate to real-time image generation. An exemplary apparatus for real time image generation includes at least an optical system, a slide port configured to hold a slide, an actuator mechanism mechanically connected to a mobile element, a user interface comprising an input interface and an output interface, at least processor configured to: using the at least an optical system, capture a first image of the slide at a first position, modify the first image, using the output interface, display the first image to a user, using the input interface, receive a parameter set from the user.
An apparatus for generating a confidence score associated with a scanned label is disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a profile comprising at least a label containing a plurality of metadata associated with the at least a label. The memory instructs the processor to generate a scanned label as a function of the at least a label, wherein generating a scanned label comprises scanning the at least a label using a text recognition module. The memory instructs the processor to determine a confidence score associated with the at least a label as a function of a comparison between the scanned label and a plurality of historical scanned labels. The memory instructs the processor to display the confidence score using a display device.
G06K 7/14 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire utilisant la lumière sans sélection des longueurs d'onde, p. ex. lecture de la lumière blanche réfléchie
Described herein are systems and methods for digitizing a slide. A system may include a slide; an optical system; and a computing device configured to identify metadata associated with the slide; determine a first scanning parameter as a function of the metadata; and using the optical system, capture a z-stack as a function of the first scanning parameter.
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
58.
APPARATUS AND A METHOD FOR GENERATING A CONFIDENCE SCORE ASSOCIATED WITH A SCANNED LABEL CROSS-REFERENCE TO RELATED APPLICATIONS
An apparatus for generating a confidence score associated with a scanned label is disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a profile, wherein the profile includes at least a label and a plurality of digital representations of slides, perform a flip detection process on the profile to verify the orientation of at least slide data of the profile, generate a scanned label as a function of the at least a label, determine a confidence score associated with the scanned label, adjust the confidence score for accuracy, and display the confidence score using a display device.
G06K 7/14 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire utilisant la lumière sans sélection des longueurs d'onde, p. ex. lecture de la lumière blanche réfléchie
59.
IMAGING DEVICE AND A METHOD FOR IMAGE GENERATION OF A SPECIMEN
An imaging device for image generation of a specimen is disclosed. Layers of images may be captured by an optical system and then compiled to create an integrated image. Each layer may include a different focal point. A consolidated image may then be created by combining one or more integrated images.
H04N 23/69 - Commande de moyens permettant de modifier l'angle du champ de vision, p. ex. des objectifs de zoom optique ou un zoom électronique
H04N 23/68 - Commande des caméras ou des modules de caméras pour une prise de vue stable de la scène, p. ex. en compensant les vibrations du boîtier de l'appareil photo
G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
An apparatus and method for inline scanned image enrichment is provided. The apparatus includes a computing device configured to receive a plurality of subject data, generate a candidate set to model the scan focal points from, digitally capture the slide using the identified focal points through machine-learning processes, processing the captured image to optimize its viewability, and storing the captured image in an accessible repository.
An apparatus and method for automated microdissection of tissue from slides to optimize tissue harvest from regions of interest are disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to receive a stained input slide, identify a region of interest on the stained input slide, generate a segmentation map of the region of interest as a function of a segmentation algorithm, register a segmented region of interest, as a function of the segmentation map, onto an unstained slide, wherein registering the segmented region of interest includes determining an orientation of the unstained slide corresponding to the segmented region of interest of the stained input slide, recording the orientation of the unstained slide relative to a reference plane, and registering the segmented region of interest to the unstained slide.
G01N 1/28 - Préparation d'échantillons pour l'analyse
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
A method for on-demand registration of whole slide images (WSIs), comprising receiving at least two digital images, a first digital image of a reference slide and a second digital image on a candidate slide, each at a first magnification level, identifying a first region of interest (ROI) on the first digital image at a target magnification level, registering a portion of the second digital image to a portion of the first digital slide image at the first magnification level to derive a transformation matrix, applying the transformation matrix to the first ROI to identify a second ROI on the second digital image at the first magnification level, mapping the second ROI to a corresponding second ROI on the second digital image at the target magnification level, and registering the corresponding second ROI to the first ROI at the target magnification level.
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06T 7/37 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés de transformation de domaine
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
scientific laboratory research instruments being laboratory robots for use in pathology; non-medical imaging apparatus for use in pathology research; Downloadable computer software for scanning pathology slides; digital input and output scanners for use in pathology; computer hardware for automated microscope slide scanning in the field of pathology; downloadable software for automated microscope slide scanning in the field of pathology; Medical devices and apparatus, namely, scanners for pathology slides
Aspects of present disclosure relate to slide imaging. An exemplary apparatus for real time image generation includes at least an optical system, a slide port configured to hold a slide, an actuator mechanism mechanically connected to a mobile element, a user interface comprising an input interface and an output interface, at least processor configured to: receive at least a region of interest; capture, using the at least an optical system, a first image of the slide at a first position within the at least a region of interest; identify a focus pattern as a function of the first image and the first position; extrapolate a focus distance for a second position as a function of the focus pattern; and capture, using the at least an optical system, a second image of the slide at a second position and at the focus distance.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Downloadable computer software for scanning pathology slides; computer hardware for automated microscope slide scanning in the field of pathology; downloadable software for automated microscope slide scanning in the field of pathology; non-medical imaging apparatus for use in pathology research; scientific laboratory research instruments being laboratory robots for use in pathology; digital input and output scanners for use in pathology Medical devices and apparatus, namely, scanners for pathology slides
66.
Systems and methods for inline quality control of slide digitization
Described herein is a system for digitizing a slide. A system may include an optical system including at least an optical sensor; and a computing device configured to perform a scan of the slide by capturing at least a first image and capturing at least a second image, wherein performing the scan includes identifying a first scanning parameter; using the optical system, capturing the at least a first image as a function of the first scanning parameter; determining a first quality metric as a function of the at least a first image; determining a second scanning parameter as a function of the first quality metric; and using the optical system, capturing the at least a second image as a function of the second scanning parameter.
The present disclosure describes an exemplary system and method for the digitization of tissue slides based on associations among serial sections. The system includes at least a computing device, wherein the computing device includes a memory and processor communicatively connected to one another, and a scanner, configured to scan a slide and send a digitized image of the slide to the computing device. A method for the digitization of tissue slides based on associations among serial sections may include receiving a candidate tissue map associated with a candidate tissue section, receiving a reference tissue map associated with a reference tissue section, aligning the candidate tissue map to the reference tissue map, comparing the aligned candidate tissue map to the reference tissue map, and generating a regenerated candidate tissue map as a function of the reference tissue map.
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
68.
SYSTEMS AND METHODS FOR INLINE QUALITY CONTROL OF SLIDE DIGITIZATION
Described herein is a system for digitizing a slide. A system may include an optical system including at least an optical sensor; and a computing device configured to perform a scan of the slide by capturing at least a first image and capturing at least a second image, wherein performing the scan includes identifying a first scanning parameter; using the optical system, capturing the at least a first image as a function of the first scanning parameter; determining a first quality metric as a function of the at least a first image; determining a second scanning parameter as a function of the first quality metric; and using the optical system, capturing the at least a second image as a function of the second scanning parameter.
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
69.
Apparatus and method for identifying regions of interest during slide digitization
An apparatus for identifying regions of interest during slide digitization is disclosed. The apparatus includes at least processor and a memory communicatively connected to the processor. The memory contains instructions configuring the processor to receive a user dataset associated with at least a pathology slide. The memory contains instructions configuring the processor to identify one or more regions of interest within at least a pathology slide as a function of the user dataset. The memory contains instructions configuring the processor to identify at least one scan parameter as a function of the one or more regions of interest. The memory contains instructions configuring the processor to generate a digitized slide by scanning the at least a pathology slide as a function the at least one scan parameter.
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 70/60 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pathologies
70.
SYSTEM AND METHOD FOR VISUALIZATION OF DIGITIZED SLIDES
A method for visualization of digitized slides is disclosed. The method comprises retrieving, by one or more computer processors, a digitized slide, determining, by the one or more computer processors, one or more visualization components of the digitized slide, generating, by the one or more computer processors, a virtual slide corresponding to the digitized slide based on the one or more visualization components, and displaying, by the one or more computer processors, a visualization of the virtual slide.
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
72.
System and method for visualization of digitized slides
A method for visualization of digitized slides is disclosed. The method comprises retrieving, by one or more computer processors, a digitized slide, determining, by the one or more computer processors, one or more visualization components of the digitized slide, generating, by the one or more computer processors, a virtual slide corresponding to the digitized slide based on the one or more visualization components, and displaying, by the one or more computer processors, a visualization of the virtual slide.
A system for detecting and cleaning contaminants from an imaging optical path, comprising an imaging device configured to receive a slide and capture a first slide image, at least a computing device configured to determine a contaminant presence indicator associated with a contaminant within an optical path of the imaging device based on the first slide image and execute a contaminant cleaning protocol as a function of the contaminant presence indicator, a contaminant removal mechanism configured to remove the contaminant from the optical path according to the contaminant cleaning protocol, wherein the computing device is further configured to re-evaluate the contaminant presence indicator based on a second slide image of the slide captured using the imaging device and request a user input upon a positive re-evaluation of the contaminant presence indicator.
An apparatus for visualization of digitized glass slides belonging to a patient case having a processor and a memory communicatively connected to the processor, the memory containing instructions configuring the processor to receive an image data set having a plurality of images of one or more specimen and metadata of the plurality of images of the one or more specimen, identify one or more constituent virtualization components for each image of the plurality of images within image data set, determine a relationship between the one or more constituent visualization components as a function of the image data set, construct a plurality of virtual images as a function of the image data set and the relationship between the one or more virtual constituent components, wherein each of plurality of the images includes at least one virtual constituent component generate a consolidated virtual image as a function of the plurality of virtual images and display the consolidated virtual image.
G06V 10/24 - Alignement, centrage, détection de l’orientation ou correction de l’image
G06V 10/74 - Appariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
Aspects of present disclosure relate to slide imaging. An exemplary system for imaging a slide includes at least an optical system, including an optical sensor; a slide port configured to hold a slide; and a first computing device configured to: capture, using the at least an optical system, a plurality of images of the slide, including a first image; automatically select an algorithm to apply to the first image; identify a control command as a function of the first image; and capture, using the at least an optical system, a second image of the plurality of images as a function of the control command.
An apparatus and method of hot-swapping a component of a component unit in a cluster. The apparatus includes a memory communicatively connected to at least a processor, the memory contains instructions configuring the at least a processor to receive quality control data from each functioning component of a component unit in at least a cluster, determine a degree of quality of each functioning component of the component unit in the at least a cluster as a function of the quality control data, determine a swappable component in the component unit of the at least a cluster as a function of the degree of quality and initiate a hot-swap procedure for the swappable component, wherein initiating the hot-swap procedure includes deregistering the swappable component from the component unit and registering a replacement component in place of the swappable component to the component unit.
A system for slide marking technique for target tissue extraction and downstream application includes at least a marking device configured to receive a sample associated with a stained slide, to image an unstained surface of the sample associated with the stained slide, and to mark a region of interest on the sample. The system includes at least a computing device comprising at least a processor and a memory, the computing device configured to receive a stained slide image, the computing device configured to receive the image of the unstained surface of the sample, the computing device configured to determine a geometric registration of the unstained surface of the sample to the stained slide image, wherein determining the geometric registration comprises aligning the stained slide image with the image of the unstained surface, the computing device configured to determine the annotation mask as a function of the geometric registration.
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06T 7/80 - Analyse des images capturées pour déterminer les paramètres de caméra intrinsèques ou extrinsèques, c.-à-d. étalonnage de caméra
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G06V 20/70 - Étiquetage du contenu de scène, p. ex. en tirant des représentations syntaxiques ou sémantiques
78.
System and methods for color gamut normalization for pathology slides
A system for color gamut normalization for pathology slides, the system including at least computing device, wherein the computing device is configured to receive a whole slide image, generate a plurality of segments associated with the whole slide image as a function of one or more biological tissue type variabilities, apply a segment-specific transformation to each segment of the plurality of segments, create a user interface data structure, wherein the user interface data structure includes the plurality of segments and display the plurality of segments through a graphical user interface as a function of the user interface data structure.
A system for color gamut normalization for pathology slide is disclosed. The system includes at least a computing device, wherein the computing device is configured to generate a plurality of segmentations of a whole slide image, wherein the whole slide image includes a plurality of biological tissue type variabilities. The computing device is configured to apply a segment-specific transformation to an individual segment in a first region. The computing device is configured to apply the segment-specific transformation to an individual segment in a second region. The computing device is configured to retrieve a plurality of discrete magnification levels from a user. The computing device is configured to choose as a first magnification level from the plurality of discrete magnification levels, and the computing device is configured to store the plurality of segmentations in a cache.
An apparatus and method for inline scanned image enrichment is provided. The apparatus includes a computing device configured to receive a plurality of subject data, generate a candidate set to model the scan focal points from, digitally capture the slide using the identified focal points through machine-learning processes, processing the captured image to optimize its viewability, and storing the captured image in an accessible repository.
An imaging device for image generation of a specimen is disclosed. Layers of images may be captured by an optical system and then compiled to create an integrated image. Each layer may include a different focal point. A consolidated image may then be created by combining one or more integrated images.
H04N 23/695 - Commande de la direction de la caméra pour modifier le champ de vision, p. ex. par un panoramique, une inclinaison ou en fonction du suivi des objets
G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
An apparatus for generating a confidence score associated with a scanned label is disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a profile comprising at least a label containing a plurality of metadata associated with the at least a label. The memory instructs the processor to generate a scanned label as a function of the at least a label, wherein generating a scanned label comprises scanning the at least a label using a text recognition module. The memory instructs the processor to determine a confidence score associated with the at least a label as a function of a comparison between the scanned label and a plurality of historical scanned labels. The memory instructs the processor to display the confidence score using a display device.
G06K 7/14 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire utilisant la lumière sans sélection des longueurs d'onde, p. ex. lecture de la lumière blanche réfléchie
83.
System and methods for color gamut normalization for pathology slides
A system for color gamut normalization for pathology slide is disclosed. The system includes at least a computing device, wherein the computing device is configured to generate a plurality of segmentations of a whole slide image, wherein the whole slide image includes a plurality of biological tissue type variabilities. The computing device is configured to apply a segment-specific transformation to an individual segment in a first region. The computing device is configured to apply the segment-specific transformation to an individual segment in a second region. The computing device is configured to retrieve a plurality of discrete magnification levels from a user. The computing device is configured to choose as a first magnification level from the plurality of discrete magnification levels, and the computing device is configured to store the plurality of segmentations in a cache.
A system of digitalizing a slide, comprising at least one imaging device and a computing device communicatively connected to the imaging device, wherein the computing device is configured to scan each slide of a plurality of slides at the imaging device to generate an initial slide image and associated scanning metadata for each slide, determine a quality control metric for each slide as a function of the initial slide image and the associated scanning metadata, wherein determining the quality control metric includes flagging the slide based on the determined quality control metric, generate at least one scanning profile as a function of the scanning metadata based on the quality control metric, and re-scan the flagged slides at the imaging device using the at least one scanning profile.
Aspects of present disclosure relate to real-time image generation. An exemplary apparatus for real time image generation includes at least an optical system, a slide port configured to hold a slide, an actuator mechanism mechanically connected to a mobile element, a user interface comprising an input interface and an output interface, at least processor configured to: using the at least an optical system, capture a first image of the slide at a first position, modify the first image, using the output interface, display the first image to a user, using the input interface, receive a parameter set from the user.
As apparatus for detecting associations among datasets of different types is disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a plurality of datasets from a user. The memory instructs the processor to identify a first set of associations between the plurality of datasets. The memory instructs the processor to generate a second set of associations as a function of the first set of associations using a second association classifier. Generating a second set of associations includes training the second association classifier using a using second association training data, wherein second association training data comprises a plurality of data entries containing the first set of associations as inputs correlated to the second set of associations as outputs The memory instructs the processor to display the second set of associations using a display device.
G06F 16/38 - Recherche caractérisée par l’utilisation de métadonnées, p. ex. de métadonnées ne provenant pas du contenu ou de métadonnées générées manuellement
87.
APPARATUS AND A METHOD FOR DETECTING ASSOCIATIONS AMONG DATASETS OF DIFFERENT TYPES
As apparatus for detecting associations among datasets of different types is disclosed. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a plurality of datasets from a user. The memory instructs the processor to identify a first set of associations between the plurality of datasets. The memory instructs the processor to generate a second set of associations as a function of the first set of associations using a second association classifier. Generating a second set of associations includes training the second association classifier using a using second association training data, wherein second association training data comprises a plurality of data entries containing the first set of associations as inputs correlated to the second set of associations as outputs The memory instructs the processor to display the second set of associations using a display device.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable computer software for scanning pathology slides; downloadable software for automated microscope slide scanning in the field of pathology; scanners; digital input and output scanners for use in pathology; computer hardware for automated microscope slide scanning in the field of pathology; scientific laboratory research instruments for use in pathology; non-medical imaging apparatus for use in pathology research. Medical devices and apparatus, namely, scanners for pathology slides. Medical laboratory services; medical and scientific laboratory services, namely, whole slide scanning; digital imaging services, namely, slide scanning and slide preparation for pathology; customization of imaging technology for pathology.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Downloadable computer software for scanning pathology slides; downloadable software for automated microscope slide scanning in the field of pathology; digital input and output scanners for use in pathology; digital input and output scanners for use in pathology; computer hardware for automated microscope slide scanning in the field of pathology; scientific laboratory research instruments being laboratory robots for use in pathology; imaging instruments not for medical use being scanners for use in the field of pathology research
(2) Medical devices and apparatus, namely, scanners for pathology slides (1) Medical laboratory services in the field of pathology research; medical and scientific laboratory services, namely, whole slide scanning to digitize body tissue specimens in the field of pathology; digital imaging services, namely, slide scanning and slide preparation for pathology; providing custom services of imaging technology for pathology research
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Downloadable computer software for scanning pathology slides; downloadable software for automated microscope slide scanning in the field of pathology; digital input and output scanners for use in pathology; digital input and output scanners for use in pathology; computer hardware for automated microscope slide scanning in the field of pathology; scientific laboratory research instruments being laboratory robots for use in pathology; imaging instruments not for medical use being scanners for use in the field of pathology research
(2) Medical devices and apparatus, namely, scanners for pathology slides (1) Medical laboratory services in the field of pathology research; medical and scientific laboratory services, namely, whole slide scanning to digitize body tissue specimens in the field of pathology; digital imaging services, namely, slide scanning and slide preparation for pathology; providing custom services of imaging technology for pathology research
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable computer software for scanning pathology slides; downloadable software for automated microscope slide scanning in the field of pathology; scanners; digital input and output scanners for use in pathology; computer hardware for automated microscope slide scanning in the field of pathology; scientific laboratory research instruments for use in pathology; non-medical imaging apparatus for use in pathology research. Medical devices and apparatus, namely, scanners for pathology slides. Medical laboratory services; medical and scientific laboratory services, namely, whole slide scanning; digital imaging services, namely, slide scanning and slide preparation for pathology; customization of imaging technology for pathology.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Digital input and output scanners for use in pathology; computer hardware for automated microscope slide scanning in the field of pathology; scientific laboratory research instruments being laboratory robots for use in pathology; non-medical imaging apparatus for use in pathology research Medical devices and apparatus, namely, scanners for pathology slides Medical and scientific laboratory services, namely, whole slide scanning; digital imaging services for medical research purposes, namely, slide scanning and slide preparation for pathology; customization of imaging technology for pathology Digital imaging services for medical diagnostic purposes, namely, slide scanning and slide preparation for pathology
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Digital imaging services for medical diagnostic purposes, namely, slide scanning and slide preparation for pathology Digital input and output scanners for use in pathology; computer
hardware for automated microscope slide scanning in the field of
pathology; scientific laboratory research instruments being laboratory
robots for use in pathology; non-medical imaging apparatus for use in
pathology research Medical devices and apparatus, namely, scanners for pathology slides Medical and scientific laboratory services, namely, whole slide
scanning; digital imaging services for medical research purposes,
namely, slide scanning and slide preparation for pathology;
customization of imaging technology for pathology
