ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Nicolay, Renaud
Van Zee, Nathan Jay
Formon, Georges Jacques Marie
Jayaratnam, Jonathan
Abrégé
The present invention relates to a process for preparing a crosslinked polymer composition containing exchangeable pending links and exchangeable crosslinks, by boronic ester metathesis reactions, said process implementing a thermoplastic polymer comprising pending boronic ester groups, and an additive as crosslinking agent that melts, and thus crosslinks, in the polymer matrix at a temperature, called temperature of dissociation, higher that the processing temperature. Said temperature of dissociation is reached in the later curing step only.
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Tanter, Michael
Deffieux, Thomas
Renaudin, Noémi
Demené, Charlie
Abrégé
Method for imaging vascular activity dynamically at a microscopic scale in a vascular network of a human or animal, the method including: (a) performing a temporal series of Ultrasound Localization Microscopy images of a region of the vascular network, to obtain values of a vascular dynamics parameter in an area of interest in the region, a recording period of the temporal series of ULM images corresponding to a dynamical event, due to a cause other than cardiac pulsatily, which activates the vascular network in the region; (b) computing, based on the values of the vascular dynamics parameter, a measure of an evolution of the vascular dynamics parameter in response to the dynamical event.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Leridon, Brigitte
Federicci, Rémi
Hole, Stéphane
Finocchi, Fabio
Abrégé
The description relates to a battery device comprising: - electrodes comprising an anode and a cathode; and - an electrolyte, between the electrodes, comprising a crystalline material having the composition M2B2O5.x(HOH).y(NOH), where M and N are alkaline elements or hydrogen, or mixtures of alkaline elements or hydrogen, B is titanium, O and H denote the elements oxygen and hydrogen, respectively, and x and y are between 0 and 4 and denote the presence of H+, OH-, N+ ions, which are capable of migrating into the crystalline material. In particular, at least one type of ion from among H+, OH-, N+ and M+ is movable so as to migrate into the crystalline material towards at least one of the electrodes, and the at least one of the electrodes is made of a material capable of carrying out a chemical interaction with at least one of the H+, OH-, M+ and N+ ions.
H01M 10/0561 - Accumulateurs à électrolyte non aqueux caractérisés par les matériaux utilisés comme électrolytes, p. ex. électrolytes mixtes inorganiques/organiques l'électrolyte étant constitué uniquement de matériaux inorganiques
H01M 10/26 - Emploi de matériaux spécifiés comme électrolytes
H01M 4/46 - Alliages à base de magnésium ou d'aluminium
H01M 4/48 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p. ex. LiTi2O4 ou LiTi2OxFy
H01M 4/54 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'argent
H01M 4/583 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Klimenko, Alexandra
Joly, Michèle
Ding, Lei
Abrégé
2222 2 in the solution; collecting a flow of solution exiting the subterranean formation or the sample thereof; and measuring the concentration of the surfactant in the flow of solution exiting the subterranean formation or the sample thereof.
C09K 8/584 - Compositions pour les méthodes de récupération assistée pour l'extraction d'hydrocarbures, c.-à-d. pour améliorer la mobilité de l'huile, p. ex. fluides de déplacement caractérisées par l'utilisation de tensio-actifs spécifiques
C09K 8/594 - Compositions utilisées en combinaison avec du gaz injecté
E21B 41/00 - Matériel ou accessoires non couverts par les groupes
E21B 49/08 - Prélèvement d'échantillons de fluides ou test des fluides dans les trous de forage ou dans les puits
5.
ANTIGENIC PEPTIDES DERIVING FROM UROCORTIN 3 AND USES THEREOF FOR THE DIAGNOSIS AND TREATMENT OF TYPE 1 DIABETES
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Mallone, Roberto
Gonzalez-Duque, Sergio
Verdier, Yann
Azoury, Marie-Eliane
Afonso, Georgia
Vinh, Joëlle
Abrégé
Despite the notion that human CD8+ T cells are the final mediators of autoimmune β-cell destruction in type 1 diabetes (T1D), none of their target epitopes has been demonstrated to be naturally processed and presented by β cells. The inventors therefore performed an epitope discovery study combining HLA Class I peptidomics and transcriptomics strategies. Inflammatory cytokines increased β-cell peptide presentation in vitro, paralleling upregulation of HLA Class I expression. Peptide sources included known β-cell antigens and several insulin granule proteins. Urocortin 3 was identified as a novel β-cell antigen, which was processed into HLA-A2-and HLA-A3-restricted epitopes recognized by circulating naïve CD8+ T cells in type 1 diabetic and healthy donors. Accordingly, the present invention relates to antigenic peptides derived from urocortin-3 and uses thereof for the diagnosis and treatment of T1D.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Carreira Rufato, Raul
Guerin, Fabrice
Lebey, Thierry Michel André
Abrégé
The invention relates to a method for detecting electric arcs in an electrical circuit of an aeronautical system, which method comprises a first phase (P1) of identifying recurring patterns in the behaviour of the electric current, on an electric line of the electrical circuit, and storing the recurring patterns in a pattern database, and a second diagnostic phase (P2) which involves comparing the behaviour of the electric current on the electric line with recurring patterns stored in the pattern database, and detecting an electric arc when the behaviour does not correspond to a recurring pattern stored in the pattern database.
G01R 31/00 - Dispositions pour tester les propriétés électriquesDispositions pour la localisation des pannes électriquesDispositions pour tests électriques caractérisées par ce qui est testé, non prévues ailleurs
G01R 31/12 - Test de la rigidité diélectrique ou de la tension disruptive
7.
AZIDO-SUBSTITUTED HETEROAROMATIC ADDITIVES FOR PREPARING RECYCLABLE POLYMER COMPOSITIONS AND FOR UPCYCLING PLASTICS WASTES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Clerget, Mattéo
Panizza, Pascal
Lequeux, François
Abrégé
The present invention relates to a method for monitoring gas bubbles in a device comprising a bubble-generating portion and a tube having an inlet and an outlet. The method comprises the steps of: separately feeding a flow of gas and a flow of liquid to the bubble-generating portion; generating individual bubbles of gas in the liquid in the bubble-generating portion; flowing the generated bubbles within the tube, from the inlet to the outlet thereof; wherein the absolute pressure at the inlet of the tube is at least 10% higher than the absolute pressure at the outlet of the tube; and simultaneously recording images of the bubbles at a plurality of positions along the tube with one or more cameras.
G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
B01J 10/00 - Procédés chimiques généraux faisant réagir un liquide avec des milieux gazeux autrement qu'en présence de particules solidesAppareillage spécialement adapté à cet effet
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
9.
METAL ORGANIC FRAMEWORKS FOR THE SELECTIVE CAPTURE OF VOLATIL ORGANIC COMPOUNDS COMPRISING CARBOXYLIC ACID FUNCTIONAL GROUP(S) AND/OR VOLATILE ALCOHOLS
Centre National de la Recherche Scientifique (France)
Ecole Normale Superieure (France)
Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris (France)
Instituto Superior Tecnico (Portugal)
Inventeur(s)
Severino Neves, Maria Ines
Serre, Christian
Nouar, Farid
Pinto, Moises
Al Mothar, Abeer
Freitas, Catia
Abrégé
The present invention relates, inter alia, to the use of porous crystalline solids constituted of a metal-organic framework (MOF) for the selective capture of volatile organic compounds (VOCs) comprising carboxylic acid functional group(s) and/or volatile organic compounds (VOCs) comprising an hydroxyl functional group.
The present invention relates, inter alia, to the use of porous crystalline solids constituted of a metal-organic framework (MOF) for the selective capture of volatile organic compounds (VOCs) comprising carboxylic acid functional group(s) and/or volatile organic compounds (VOCs) comprising an hydroxyl functional group.
The MOF solids of the present invention can be used for the purification of air, for example for the selective capture of VOCs comprising carboxylic acid functional group(s) and/or volatile organic compounds (VOCs) comprising an hydroxyl functional group from outdoor air. It may be used for art preservation, such as the conservation of cellulose derivate films, for indoor air purification systems such as HEPA air filters, adsorbent purifiers, kettle filters, fette filters, honeycomb filters or air conditioning filters, for outdoor air purification systems such as gas mask, nose filter, adsorption columns or chimney filters, and in cosmetic applications such as deodorants, anti-odor shampoo, hygienic protection products, wipes or diapers.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
10.
METHODS AND SYSTEMS FOR THREE-DIMENSIONAL IMAGING OF A TRANSPARENT BIOLOGICAL OBJECT IN A BIOLOGICAL SAMPLE BY FULL-FIELD OPTICAL TOMOGRAPHY
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Boccara, Albert Claude
Boccara, Martine
Thouvenin, Olivier
Abrégé
A three-dimensional imaging system including a light source configured to emit a beam of spatially incoherent light, having a given central length, configured to illuminate a biological sample being transmitted; an optical imaging system including a microscope lens with a given object focal plane near which the sample is positioned; mechanisms for axially moving the microscope lens relative to the sample; a two-dimensional acquisition device including a plurality of elementary detectors arranged in a detection plane optically conjugate with the object focal plane and a processing unit. For each section of a biological object of the sample, a plurality of two-dimensional interferometric signals resulting from optical interference between the illumination beam and a beam scattered by an object field of the section are acquired and at least a first image is calculated from the plurality of two-dimensional interferometric signals.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
MUSEUM NATIONAL D'HISTOIRE NATURELLE (France)
ECOLE NORMALE SUPERIEURE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Tignol, Pierre
Dupont, Anne-Laurence
Pimenta, Vanessa
Serre, Christian
Lavedrine, Bertrand
Abrégé
A method for preparing a porous membrane, comprising the following steps of:
a—preparing an aqueous mixture comprising a dispersion of fibres derived from an organic material in water, a solid organic binder and porous solid particles suspended in water;
b—leaving the obtained aqueous mixture comprising the fibres, the organic binder and the porous solid particles under stirring for at least 10 min at room temperature;
c—vacuum filtering the mixture and recovering a composite material; and
d—pressing said composite material obtained in step c—to form a porous membrane.
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Bureau, Flavien
Giraudat, Elsa
Le Ber, Arthur
Lambert, William
Fink, Mathias
Aubry, Alexandre
Abrégé
uiui(t) defined between an emission basis (i) as input and a reception basis (u) as output, a step of determining a de-scanned reflection matrix R' of the medium between an input virtual transducer calculated on the basis of an input focus of the experimental reflection matrix and an output virtual transducer calculated on the basis of an output focus of the experimental reflection matrix, the virtual transducers being at the same depth. The method comprises a step of extracting an optimal position deviation or an optimal speed-of-sound model from the focal-spot image.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Bureau, Flavien
Giraudat, Elsa
Le Ber, Arthur
Lambert, William
Fink, Mathias
Aubry, Alexandre
Abrégé
uiui(t) defined between the input emission basis (i) and an output reception basis (u), a step of determining a de-scanned reflection matrix R' of the medium between an input virtual transducer calculated based on an input focus of the experimental reflection matrix and an output virtual transducer calculated based on an output focus of the experimental reflection matrix, the virtual transducers being at the same depth. The method comprises a step of extracting an optimal position offset or an optimal speed-of-sound model from this focal-spot image.
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Tanter, Mickael
Deffieux, Thomas
Lebrin, Franck
Morisset, Clémentine
Abrégé
Functional imaging, in particular functional ultrasound imaging, is becoming a powerful tool for early detection of disorders such as neurodegenerative diseases. The present disclosure proposes a reliable method for such early detection, by delivering a stimulus to the nervous system, performing a functional imaging of an area of interest of the nervous system activated by the stimulus to obtain a series of hemodynamic Doppler images of the vascular network in the area of interest, and computing, from the series of hemodynamic Doppler images, a hemodynamic response (22) to the stimulus. The shape of hemodynamic response may be used to detect health disorders.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Colin, Annie
Brahmi, Youcef
Wu, Nan
Abrégé
The invention relates to a device (1) for producing electricity, the device (1) comprising a cell (2), the cell having two compartments (31, 32), wherein each compartment has a surface (41, 42) for adsorbing a predetermined ion, and the two compartments are separated by a membrane (5) that is porous to at least the predetermined ion. The two compartments are each intended to receive a liquid (L1, L2) having different concentrations of the predetermined ion. The cell comprises two terminals (61, 62) respectively connected to the adsorption surfaces of the two compartments, which cell is capable of creating a difference in potential Eocv across its two terminals in the presence of the respective liquids in the two compartments. The device (1) further comprises a voltage generator (7), the generator (7) comprising two terminals (71, 72), one (71) of which is connected to a terminal (62) of the cell, the generator being arranged to produce a difference in potential E0 across its two terminals; the other terminal (72) of the generator constitutes one terminal (82) of the device, and the other terminal (81) of the device consists of the other terminal (61) of the cell.
H01G 11/02 - Condensateurs hybrides, c.-à-d. ayant des électrodes positive et négative différentesCondensateurs électriques à double couche [EDL]Procédés de fabrication desdits condensateurs ou de leurs composants utilisant des combinaisons de réactions de réduction et d'oxydation, p. ex. dispositifs redox ou solion
H01G 11/08 - Combinaisons structurelles, p. ex. assemblage ou connexion de condensateurs hybrides ou EDL avec d’autres composants électriques, au moins un condensateur hybride ou EDL étant le composant principal
H01G 11/14 - Agencements ou procédés de réglage ou de protection des condensateurs hybrides ou EDL
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
URGO RECHERCHE INNOVATION ET DEVELOPPEMENT (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT POLYTECHNIQUE DE BORDEAUX (France)
Inventeur(s)
Pernot, Jean-Marc
Vidil, Thomas
Cramail, Henri
Clair, Charles
Leibler, Ludwik
Labousse, Matthieu
Abrégé
The present invention relates to a method for synthesising a triblock copolymer, comprising the following steps: (1) reacting (A) a polydimethylsiloxane (PDMS) comprising at least two amine end groups, either primary amine groups (-NH2) and/or secondary amine groups (-NH(alkyl)), with (B) a molar excess, relative to all the molecules of type (A), of a molecule comprising at least two isocyanate groups (-N=C=O), in order to obtain a prepolymer terminated by isocyanate groups; (2) reacting the prepolymer obtained in step (1) with a polyamide comprising an amine end group (-NH2), the number of moles of polyamide comprising an amine end group (-NH2) being at least equivalent to the number of moles of isocyanate groups (-N=C=O) in the prepolymer obtained in step (1). The present invention also relates to a triblock copolymer obtained in this way, and to the use thereof in dressings.
A61F 13/00 - Bandages ou pansementsGarnitures absorbantes
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
C08G 18/28 - Polymérisats d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs caractérisés par l'emploi de composés spécifiés contenant un hydrogène actif
C08G 77/455 - Polymères séquencés ou greffés contenant des segments de polysiloxanes contenant des segments de polymères contenant de l'azote contenant des segments de polyamides, polyesteramides ou polyimides
C08G 77/458 - Polymères séquencés ou greffés contenant des segments de polysiloxanes contenant des segments de polymères contenant de l'azote contenant des segments de polyuréthanes
C08G 77/54 - Composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant du silicium, avec ou sans soufre, azote, oxygène ou carbone dans lesquels au moins deux atomes de silicium, mais pas la totalité, sont liés autrement que par des atomes d'oxygène liés par l'azote
A61F 13/0246 - Bandages ou pansements adhésifs caractérisés par la couche adhérant à la peau
17.
TRACHEAL INTUBATION BALLOON CUFF THROUGH WHICH FLUID PASSAGE DUCTS EXTEND
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
SORBONNE UNIVERSITE (France)
UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (France)
Inventeur(s)
Bergounioux, Jean
Siefert, Emmanuel
Bico, José
Reyssat, Etienne
Roman, Benoit
Abrégé
The invention relates to a balloon cuff (1) for a tracheal intubation device, the balloon cuff (1) being elastically deformable and extending between an inner surface (3) surrounding an axis (A) and an outer surface (5) surrounding the inner surface (3), the balloon cuff (1) comprising inner walls that define ducts (13, 15) that extend through the balloon cuff, the balloon cuff (1) being configured to go from a deflated state to an inflated state by injecting a fluid into the ducts (13, 15) such that the outer surface (5) moves away from the axis.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Vinh, Joëlle
Verdier, Yann
Xu, Zeyuan
Abrégé
The present invention concerns a novel fusion polypeptide comprising a polypeptide having an N- glycosidase activity fused to an antioxidant moiety, wherein the polypeptide having an N-glycosidase activity is a polypeptide from a bacterium belonging to the Acidobacteria phylum, preferably to the Acidobacteriia class. The present invention also concerns the nucleic acid molecule, vector, and host cell encoding the fusion polypeptide, as well as compositions and kits thereof. The present invention also provides methods for purifying and/or for producing the fusion polypeptide, as well as in vitro use of the fusion polypeptide, or the nucleic acid molecule, vector, or host cell encoding the fusion polypeptide, or compositions thereof.
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Renaudin, Noémi
Tanter, Mickaël
Demene, Charlie
Osmanski, Bruno-Félix
Abrégé
Method for imaging vascular activity at a microscopic scale in at least one area of a vascular network of an organ, of a human or animal, the method including: (a) transmitting a series of successive incident ultrasonic waves in the at least one area by an array of ultrasonic transducers, the array of ultrasonic transducers extending along at least one direction and the incident ultrasonic waves being propagated in a direction perpendicular to the array of transducers; (b) acquiring a set of raw data from backscattered ultrasonic waves by said array of transducers; (c) generating a series of successive ultrasound images from said raw data; (d) detecting at least one isolated ultrasound contrast agent in the ultrasound images; (e) localizing the position of said at least one isolated ultrasound contrast agent with a precision inferior to the wavelength of the waves; (f) generating an at least 2D backscattering amplitude image by attributing for each pixel a value representative of the measured backscattering amplitude of at least one isolated ultrasound contrast agent detected in said pixel.
Institut National de la Santé et de la Recherche Médicale (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (France)
Inventeur(s)
Renaudin, Noémi
Tanter, Mickaël
Demené, Charlie
Osmanski, Bruno-Felix
Abrégé
Method for imaging vascular activity at a microscopic scale in at least one area of a vascular network of an organ, of a human or animal, the method including:
(a) transmitting a series of successive incident ultrasonic waves in the at least one area by an array of ultrasonic transducers, the array of ultrasonic transducers extending along at least one direction and the incident ultrasonic waves being propagated in a direction perpendicular to the array of transducers;
(b) acquiring a set of raw data from backscattered ultrasonic waves by said array of transducers;
(c) generating a series of successive ultrasound images from said raw data;
(d) detecting at least one isolated ultrasound contrast agent in the ultrasound images;
(e) localizing the position of said at least one isolated ultrasound contrast agent with a precision inferior to the wavelength of the waves;
(f) generating an at least 2D backscattering amplitude image by attributing for each pixel a value representative of the measured backscattering amplitude of at least one isolated ultrasound contrast agent detected in said pixel.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLE DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Carreira Rufato, Raul
Bussy, Emmanuel
Lebeyf, Thierry Michel André
Oussar, Yacine
Ditchi, Thierry
Abrégé
arcIsourcearcIsourcearcarc and the constants of the knowledge model at output; the method comprising continuously detecting the presence of an arc using a decision function depending on a cost function used in the learning phase.
G01R 31/12 - Test de la rigidité diélectrique ou de la tension disruptive
G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle
G06N 3/044 - Réseaux récurrents, p. ex. réseaux de Hopfield
G06N 7/01 - Modèles graphiques probabilistes, p. ex. réseaux probabilistes
G01R 19/25 - Dispositions pour procéder aux mesures de courant ou de tension ou pour en indiquer l'existence ou le signe utilisant une méthode de mesure numérique
G01R 31/00 - Dispositions pour tester les propriétés électriquesDispositions pour la localisation des pannes électriquesDispositions pour tests électriques caractérisées par ce qui est testé, non prévues ailleurs
22.
NOVEL COMPOSITIONS AND THEIR USE TO INCREASE MOTILITY, VIABILITY AND LIFESPAN OF SPERM CELLS AND FERTILITY
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Schmitt, Eric
Carion, Olivier
Pipart, Perrine
Camugli, Sabine
Hourdet, Dominique
Tran, Yvette
Abrégé
The present invention relates to novel compositions, process for manufacturing said compositions and use thereof for increasing motility, viability and lifespan of sperm cells, and fertility.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Pruvost, Mickaël
Gauthier, Anaïs
Colin, Annie
Abrégé
The present invention relates to a device for locally measuring a normal mechanical stress exerted by a contact element, said device comprising:—a substrate comprising, over at least a part of its surface, at least one electrically conductive layer, called the lower electrode,—a first electrically insulating polymeric layer having a thickness of between 1 μm and 500 μm and comprising at least one through-cavity, the first polymeric layer being arranged on the substrate,—a structure arranged on the first polymeric layer, the structure comprising the following successive layers.
G01L 9/00 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pressionTransmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent
24.
SYSTEMS AND METHODS FOR ENZYMATIC DEGRADATION OF POLYMERS, INCLUDING COPOLYMERS, WITH A VARIETY OF ENZYMES
Centre National de la Recherche Scientifique (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Leibler, Ludwik
Tournilhac, François
Freymond, Clément
Garate, Hernan
Bréloy, Louise
Griffiths, Andrew
Rondelez, Yannick
Mansaku, Brian
Pallis, Jack
Gibbs, Benjamin
Abrégé
Systems, methods, and compositions relating to pretreatment and enzymatic degradation of polymeric materials comprising one or more crystallizable polymers or copolymers are generally described. Certain aspects are directed to methods comprising reacting a polymeric material comprising a crystallizable polymer or copolymer with a reactive agent to produce a pretreated polymeric material and exposing the pretreated polymeric material to a polymer-degrading enzyme. In some embodiments, the reactive agent induces chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some embodiments, the reactive agent induces chain scissions followed by chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some cases, the methods further comprise a thermal annealing step following the step of reacting the polymeric material comprising the crystallizable polymer or copolymer with the reactive agent and prior to the step of exposing the pretreated polymeric material to the polymer-degrading enzyme. During the thermal annealing step, further chain reactions (e.g., chain scission, extension, branching, and/or cross-linking) may occur.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
UNIVERSITE PARIS-SACLAY (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Fort, Emmanuel
Levêque-Fort, Sandrine
Lengauer, Maximilien
Abrégé
The invention relates to a device (100) for locating an individual particle (2) in a sample (3) having a plurality of regions (31), the particle being capable of emitting photons when it receives light, the device comprising: - a sample holder (110); - a light source arranged to produce an illumination field suitable for illuminating the sample placed on its holder, an intensity of the illumination field having a temporal and spatial variation such that the intensity has, in each region of the sample, a predetermined temporal pattern different from the temporal patterns of the intensity in the other regions; - a detector (140) capable of converting photons emitted by the particle in response to the illumination thereof by the illumination field into a signal representative of the intensity of the illumination field received by the particle; - a computer (150) programmed to determine, on the basis of a temporal change in the signal derived from the detector and the temporal and spatial variation in the intensity of the illumination field, the region of the sample in which the particle is located.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
OFFICE NATIONAL D’ETUDES ET DE RECHERCHES AEROSPATIALES (France)
Inventeur(s)
Meimon, Serge
Baracal De Mece, Pedro
Thouvenin, Olivier
Krafft, Léa
Abrégé
The invention relates to an imaging device (1) comprising: a linear illumination module (2) producing a line of light on an object (20); scanning means for moving the line of light on the object; a two-dimensional sensor (14) comprising a rolling shutter; a synchronization module having a first mode which has a zero time shift between the rolling shutter and the scanning means and in which the sensor (14) senses a bright-field signal, and a second mode which has a non-zero time shift between the shutter and the scanning means and in which the sensor senses a dark-field signal; and an image processing module for producing a bright-field image from the bright-field signals and produce a dark-field image from the dark-field signals. The invention also relates to an imaging method.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
27.
DEVICE AND METHOD FOR INTERFEROMETRIC IMAGING OF A DIFFUSING OBJECT
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES (France)
Inventeur(s)
Meimon, Serge
Baracal De Mece, Pedro
Thouvenin, Olivier
Krafft, Léa
Abrégé
The invention relates to an interferometric imaging device (1) comprising: - an illumination module (2) for generating a measurement beam (10) producing a line of light on an object as well as a reference beam (11); - interferometric means (8, 9) for generating an interference signal between the backscattered measurement beam and the reference beam; - a two-dimensional sensor (14) comprising a rolling shutter; - scanning means for moving the line of light on the object; - a synchronization module having a first mode with a zero time shift between the rolling shutter and the scanning means, the sensor sensing the interference signal, and a second mode with a non-zero time shift between the rolling shutter and the scanning means, the sensor sensing an incoherent signal; - a module for producing images from the interference signals and the incoherent signals.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
28.
METAL ORGANIC FRAMEWORKS POLYMORPHISM FOR ADSORPTION PROFILE TUNING
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLE DE LA VILLE DE PARIS (France)
Inventeur(s)
Maimouni, Ilham
Russo, Maria
Cossy, Janine
Tabeling, Patrick
Abrégé
Organic solid three-dimensional polymeric foams, a process for preparing the same, and use thereof, the foams includes a solid continuous phase and pores, wherein the foams have a pore size ranging from 50 nm to 200 μm and a volumetric fraction of the solid continuous phase is from 0.1 to 60%, with respect to the total volume of the foams, and a polydispersity index from 1 to 30%, the foams being ordered over a volume of at least 100 pores.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Leibler, Ludwik
Tournilhac, Francois
Freymond, Clement
Garate, Hernan
Bréloy, Louise
Griffiths, Andrew
Rondelez, Yannick
Mansaku, Brian
Pallis, Jack
Gibbs, Benjamin
Abrégé
Systems, methods, and compositions relating to pretreatment and enzymatic degradation of polymeric materials comprising one or more crystallizable polymers or copolymers are generally described. Certain aspects are directed to methods comprising reacting a polymeric material comprising a crystallizable polymer or copolymer with a reactive agent to produce a pretreated polymeric material and exposing the pretreated polymeric material to a polymer-degrading enzyme. In some embodiments, the reactive agent induces chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some embodiments, the reactive agent induces chain scissions followed by chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some cases, the methods further comprise a thermal annealing step following the step of reacting the polymeric material comprising the crystallizable polymer or copolymer with the reactive agent and prior to the step of exposing the pretreated polymeric material to the polymer-degrading enzyme. During the thermal annealing step, further chain reactions (e.g., chain scission, extension, branching, and/or cross-linking) may occur.
C08J 11/10 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation
31.
SYSTEMS AND METHODS FOR PRETREATMENT AND/OR ENZYMATIC DEGRADATION OF CRYSTALLIZABLE POLYMERS, INCLUDING COPOLYMERS
Centre National de la Recherche Scientifique (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Leibler, Ludwik
Tournilhac, François
Freymond, Clément
Garate, Hernan
Bréloy, Louise
Griffiths, Andrew
Rondelez, Yannick
Mansaku, Brian
Pallis, Jack
Gibbs, Benjamin
Abrégé
Systems, methods, and compositions relating to pretreatment and enzymatic degradation of polymeric materials comprising one or more crystallizable polymers or copolymers are generally described. Certain aspects are directed to methods comprising reacting a polymeric material comprising a crystallizable polymer or copolymer with a reactive agent to produce a pretreated polymeric material and exposing the pretreated polymeric material to a polymer-degrading enzyme. In some embodiments, the reactive agent induces chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some embodiments, the reactive agent induces chain scissions followed by chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some cases, the methods further comprise a thermal annealing step following the step of reacting the polymeric material comprising the crystallizable polymer or copolymer with the reactive agent and prior to the step of exposing the pretreated polymeric material to the polymer-degrading enzyme. During the thermal annealing step, further chain reactions (e.g., chain scission, extension, branching, and/or cross-linking) may occur.
C08J 11/10 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation
32.
SYSTEMS AND METHODS FOR ENZYMATIC DEGRADATION OF POLYMERS, INCLUDING COPOLYMERS, OF ADVANTAGOUS PARTICLE SIZE
Centre National de la Recherche Scientifique (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Leibler, Ludwik
Tournilhac, François
Freymond, Clément
Garate, Hernan
Bréloy, Louise
Griffiths, Andrew
Rondelez, Yannick
Mansaku, Brian
Pallis, Jack
Gibbs, Benjamin
Abrégé
Systems, methods, and compositions relating to pretreatment and enzymatic degradation of polymeric materials comprising one or more crystallizable polymers or copolymers are generally described. Certain aspects are directed to methods comprising reacting a polymeric material comprising a crystallizable polymer or copolymer with a reactive agent to produce a pretreated polymeric material and exposing the pretreated polymeric material to a polymer-degrading enzyme. In some embodiments, the reactive agent induces chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some embodiments, the reactive agent induces chain scissions followed by chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some cases, the methods further comprise a thermal annealing step following the step of reacting the polymeric material comprising the crystallizable polymer or copolymer with the reactive agent and prior to the step of exposing the pretreated polymeric material to the polymer-degrading enzyme. During the thermal annealing step, further chain reactions (e.g., chain scission, extension, branching, and/or cross-linking) may occur.
C08J 11/10 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation
C08J 11/26 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation par traitement avec une substance organique par traitement avec des composés organiques contenant de l'oxygène contenant des groupes acide carboxylique, leurs anhydrides ou esters
C12N 9/18 - Hydrolases agissant sur les esters d'acides carboxyliques
33.
METHOD FOR CHARACTERIZING THE VIBRATION OF A SURFACE
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
UNIVERSITE PARIS CITE (France)
ASSISTANCE PUBLIQUE – HOPITAUX DE PARIS (France)
Inventeur(s)
Ing, Ros-Kiri
Fink, Mathias
Similowski, Thomas
Abrégé
The invention relates to a method for characterizing the vibration of a surface of the chest of an individual, said method including generating an incident vibration of the respiratory system of the individual, said incident vibration having at least one frequency from 20 Hz to 5000 Hz, to obtain resultant vibrations at a surface S of the chest of the individual, said surface S having a surface area of at least 10 cm2 and being characterized by a plurality of points Pi, and measuring the oscillation of each point Pi using a measuring device and obtaining the signal Spi of the resultant vibration at each of the points Pi, said measuring device being arranged at a distance from the chest of said individual, and characterizing each signal Spi at the frequenc(y/ies) of the signal Spr.
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
Centre National de la Recherche Scientifique (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Osmanski, Bruno-Felix
Deffieux, Thomas
Pernot, Mathieu
Bertolo, Adrien
Demene, Charlie
Abrégé
An ultrasound probe includes a connector and a probe head that includes a mount located in a tip part of the probe head, various linear matrices of transducers that emit acoustic waves with a given central wavelength and detect backscattered acoustic waves. The linear matrices are electrically connected to the connector, wherein each linear matrix from the linear matrices of transducers includes a first side along a first direction and a second side along a second direction. The second side is smaller than the first side. The linear matrices are fixed to the mount and juxtaposed on the mount with the first sides adjacent. Each linear matrix from the linear matrices of transducers is covered with a single cylindrical acoustic lens that focuses the acoustic waves emitted by the linear matrix. Each cylindrical acoustic lens includes a cylindrical axis substantially parallel to the first direction.
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Papadacci, Clément
Tanter, Mickael
Farve, Hugues
Pernot, Mathieu
Abrégé
While 3D ultrasound imaging is becoming a powerful tool in medical field. the main drawback is the difficulty to image large 3D volume. mainly related to the dimensions of the 2D array of transducers. In order to not lose in spatial resolution, it is necessary to use an array of transducers. wherein the size of the transducers does not exceed the wavelength of the ultrasound wave. Such requirement leads to dimensions of array for imaging large 3D volume which are not reachable or at too high cost with the current technology. The present disclosure overcomes the above technology limitation by using greater transducers, and where each transducer has a reception surface with a curved shape or is fitted with an acoustic lens. Such configuration of transducers leads to 2D array of transducers suitable for imaging large 3D volume, as a brain or a heart. with high resolution and high sensitivity.
A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
B06B 1/06 - Procédés ou appareils pour produire des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore utilisant l'énergie électrique fonctionnant par effet piézo-électrique ou par électrostriction
G01S 7/52 - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe
G01S 15/89 - Systèmes sonar, spécialement adaptés à des applications spécifiques pour la cartographie ou la représentation
36.
METHODS FOR THE SELECTIVE ANALYSIS OF CELLS OR ORGANELLES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Rondelez, Yannick
Griffiths, Andrew
Blivet-Bailly, Gaël
Ibanez, Pablo
Banerjee, Satyam
Gines, Guillaume
Masurier, Antoine
Abrégé
The present invention relates to a method for the selective analysis of a subpopulation of cells or organelles based determining the level of at least one cell or organelle marker, via the implementation of an adapted DNA toolbox able to convert the presence of a cell or organelle marker into a signal. This method is particularly useful for selecting cells or organelles having a phenotype of interest, analyzing the proteins of said cells or organelles and/or sequencing the DNA and/or RNA of said cells. The present invention also relates to a kit for implementing the method of selective analysis of cells or organelles as defined above.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Carreira Rufato, Raul
Lebey, Thierry Michel André
Acheen, Robin
Bussy, Emmanuel
Abrégé
The invention relates to a method for detecting and recognizing a partial discharge in electrical equipment (10) in an aeronautical environment, the method comprising a step of detecting (E10), by means of a sensor (91), an electrical signal to be analysed (1), the method being characterized in that it further comprises steps of computing (E2) at least one value of a distance parameter (3) representative of a distance between the electrical signal to be analysed (1) and at least one signature signal (2) representative of a partial discharge, the distance parameter being dependent on a difference between the electrical signal to be analysed and the signature signal, and of comparing (E3) the value of the distance parameter with a detection threshold (4) and detecting a potential partial discharge depending on a result of the comparison.
G01R 31/12 - Test de la rigidité diélectrique ou de la tension disruptive
G01R 31/00 - Dispositions pour tester les propriétés électriquesDispositions pour la localisation des pannes électriquesDispositions pour tests électriques caractérisées par ce qui est testé, non prévues ailleurs
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
TECHNISCHE UNIVERSITEIT DELFT (Pays‑Bas)
Inventeur(s)
Rondelez, Yannick
Di Meo, Thibault
Danelon, Christophe
Abil, Zhanar
Gomes, Margarida
Abrégé
The present invention provides a new method that is specifically designed to start statistically from a single copy of a nucleic acid molecule and requires only a single encapsulation step to provide clonal microcompartment libraries displaying a high concentration of encoded polypeptides. The method of the invention enables one to perform in vitro uHTS via a one-step encapsulation of linear DNA constructs containing a candidate sequence to be tested in a molecular mixture that allows for simultaneous specific gene amplification and protein expression.
C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
C12P 19/34 - Polynucléotides, p. ex. acides nucléiques, oligoribonucléotides
C12P 21/00 - Préparation de peptides ou de protéines
39.
ENZYMATIC DEGRADATION OF CRYSTALLIZABLE POLYMERS OR COPOLYMERS AND POST-CONSUMER/POST-INDUSTRIAL POLYMERIC MATERIALS CONTAINING CRYSTALLIZABLE POLYMERS OR COPOLYMERS
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Leibler, Ludwik
Garate, Hernan
Freymond, Clément
Griffiths, Andrew
Bréloy, Louise
Mansaku, Brian
Pallis, Jack
Abrégé
The present disclosure is related to systems and methods of enzymatic degradation of crystallizable polymers or copolymers and PC/IPM containing crystallizable polymers or copolymers.
C08J 11/10 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation
C08J 11/06 - Récupération ou traitement des résidus des polymères sans réaction chimique
C12N 9/18 - Hydrolases agissant sur les esters d'acides carboxyliques
C12N 9/20 - Scission des triglycérides, p. ex. au moyen de lipase
C12N 9/80 - Hydrolases (3.) agissant sur les liaisons carbone-azote autres que les liaisons peptidiques (3.5) agissant sur les liaisons amides des amides aliphatiques
B29B 17/00 - Récupération de matières plastiques ou d'autres constituants des déchets contenant des matières plastiques
B02C 19/00 - Autres dispositifs ou procédés de désagrégation
40.
OPTICAL DEVICE FOR SELF-REFERENCED FULL-FIELD TEMPORAL OPTICAL COHERENCE TOMOGRAPHY MICROSCOPIC IMAGING, AND ASSOCIATED FACILITY AND METHOD
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE HOSPITALIER D'OPHTALMOLOGIE DES QUINZE-VINGTS (France)
Inventeur(s)
Grieve, Kate
Thouvenin, Olivier
Monfort, Tual
Azzollini, Salvatore
Reichman, Sacha
Abrégé
The invention relates to an optical device for the full-field optical coherence tomography microscopic imaging of at least one sample, the device comprising a lens for observing the sample when in use, the device comprising a specular interface, the device thus being able, when in use, to allow the production of at least one interference between at least one reference wave obtained by the reflection of light emitted by a light source associated with the device from the specular interface, and at least one object wave obtained by the backscattering of the light emitted by the source from the sample, the specular interface being arranged with respect to the lens in such a way that, when in use, the object wave passes through the specular interface on its path between the sample and the source. The invention also relates to the corresponding facility and method.
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
42.
ANALYSIS OF CELLS AND/OR ORGANELLES IN HYDROGEL CAGES
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
MICROFACTORY SAS (France)
Inventeur(s)
Geisler, Hubert
Tabeling, Patrick
Griffiths, Andrew
Chiron, Stéphane
Monti, Fabrice
Blivet-Bailly, Gaël
Abdorahim, Marjan
Tran-Amarelis, Yvette
Nghe, Phillipe
Abrégé
A microfluidic device comprising: —a first wall comprising a first substrate on which a plurality of closed patterns is grafted, —a second wall, facing the first wall, comprising a second substrate, —a plurality of nucleic acids grafted either on the first substrate or on the second substrate, wherein each nucleic acid comprises a barcode that encodes the position of the nucleic acid on said first or second substrate, wherein at least the plurality of closed patterns or the second substrate is made of an actuatable hydrogel which is swellable between a retracted state and a swollen state in which the closed patterns and the second substrate come into contact.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Klimenko, Alexandra
Blondeau, Christophe
Joly, Michèle
Ding, Lei
Abrégé
12344 are independently a hydrogen atom or an alkyl group, A is an alkylene group, and the total number of carbon atoms in the surfactant compound of formula (I) is from 10 to 24.
B65G 5/00 - Emmagasinage des fluides dans des excavations ou cavités naturelles ou artificielles souterraines
E21B 41/00 - Matériel ou accessoires non couverts par les groupes
C09K 8/584 - Compositions pour les méthodes de récupération assistée pour l'extraction d'hydrocarbures, c.-à-d. pour améliorer la mobilité de l'huile, p. ex. fluides de déplacement caractérisées par l'utilisation de tensio-actifs spécifiques
C09K 8/594 - Compositions utilisées en combinaison avec du gaz injecté
44.
METHOD FOR SPATIAL MAPPING AND SEQUENCING OF CELLS OR ORGANELLES
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Griffiths, Andrew
Blivet-Bailly, Gaël
De Reyniès, Aurélien
Geisler, Hubert
Ibanez, Pablo
Nghe, Philippe
Abrégé
Method for determining tissue positions using an array, which comprise location sequences, the location sequences bind to the tissue samples via ligands. The tissue section which allows localisation tags to be assigned to areas of the tissue comprising a single or plurality of cells or organelles, e.g. about two to ten cells. By triangulation of the localisation tags it is possible to assign a unique relative position in the tissue per cell or organelle.
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
Centre National de la Recherche Scientifique (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Demene, Charlie
Osmanski, Bruno-Felix
Tanter, Mickael
Baranger, Jérôme
Baud, Olivier
Abrégé
An ultrasound probe holding device configured to attach to the head of an infant for transfontanellar imaging is disclosed, including a head pad configured to be in contact with the head of the infant and including a central opening, wherein the head pad is configured to receive an ultrasound probe; a pad squeezer, including a central opening and configured to cooperate with the head pad to allow an axial guidance of the head pad along a guidance axis substantially perpendicular to a surface tangent to the head of the infant; a device holder configured to be attached to the head of the infant and exert a downward force on the pad squeezer, along said guidance axis; and a repellent configured to exert a repellent force between the pad squeezer and the head pad when the device holder exerts the downward force on the pad squeezer.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE NORMALE SUPERIEURE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
INSTITUTO SUPERIOR TECNICO (Portugal)
FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (Portugal)
Inventeur(s)
Serre, Christian
Tissot, Antoine
Cao, Chenchen
Luzia Goncalves Pinto, Moisés
Silva, João
Antunes, Fernando
Pinto, Rosana
Abrégé
The present invention belongs to the field of nanoporous materials, in particular metal organic frameworks (MOFs) and Lewis-based gas delivery and/or slow release, or the detection of Lewis-based gas(es) in gases or liquid streams. The present invention relates, inter alia, to a new ultra-microporous crystalline metal organic framework solid ( comprising bisphosphonic acid ligands (also refered to as Phosphonate MOF), such as MIP-210(M) and uses thereof as a carrier in Lewis-based gas (such as NO) delivery. The invention also relates to controlled release of the Lewis-based gas in wounds, for example by topical application. The invention also encompasses a synthetic method for producing the new ultra- microporous crystalline metal organic framework solid of the invention. The MOFs of the present invention can be used in various applications such as gas carrier and/or for the controlled release of gas. The MOFs of the present invention thus are very versatile and have therapeutic and non therapeutic applications.
A61L 15/00 - Aspect chimique des bandages, des pansements ou des garnitures absorbantes ou utilisation de matériaux pour leur réalisation
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
B01D 53/00 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols
B01D 53/94 - Épuration chimique ou biologique des gaz résiduaires des gaz d'échappement des moteurs à combustion par des procédés catalytiques
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Lambert, William
Aubry, Alexandre
Fink, Mathias
Frappart, Thomas
Abrégé
Method for ultrasonic characterization of a medium, comprising a step of generating a series of incident ultrasonic waves, a step of generating an experimental reflection matrix Rui(t) defined between the emission basis (i) as input and a reception basis (u) as output, a step of determining a focused reflection matrix RFoc(rin, rout, δt) of the medium between an input virtual transducer (TVin) calculated based on a focusing as input to the experimental reflection matrix and an output virtual transducer (TVout) calculated based on a focusing as output from the experimental reflection matrix, the responses of the output virtual transducer (TVout) being obtained at a time instant that is shifted by an additional delay δt relative to a time instant of the responses of the input virtual transducer (TVin).
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (France)
Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (France)
Inventeur(s)
Lambert, William
Aubry, Alexandre
Fink, Mathias
Cobus, Laura
Abrégé
out) calculated based on an output focusing of the experimental reflection matrix that creates an output focal spot around a second point (P2), said response being expressed as a function of a central point (PC) of spatial position (r) in the medium located midway between the first and second points (P1, P2).
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Aubry, Alexandre
Barolle, Victor
Balondrade, Paul
Fink, Mathias Alexandre
Boccara, Albert Claude
Najar, Ulysse
Abrégé
inωωinωω frequencies; numerically determining, on the basis of the polychromatic reflection matrix, a focused bulk reflection matrix; determining, on the basis of this first focused bulk reflection matrix, at least one map having a physical parameter of the sample.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITECNICA DE VALENCIA (Espagne)
PARIS SCIENCES ET LETTRES (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONA DE LA RECHRCHE SCIENTIFIQUE (France)
ECOLE NORMALE SUPERIEURE (France)
Inventeur(s)
Navalón Oltra, Sergio
Valles Garcia, Christina
Cabrero Antonino, Maria
Garcia Gomez, Hermeagildo
Serre, Christian
Mouchaham, Georges
Zhou, Lin
Abrégé
The present invention relates to metal-organic frameworks (MOFs) which contain trimetallic centres with pyrazole as a ligand in the structure thereof. Particularly, it relates to MOFs which contain units of formula (I). The present invention also relates to a photocatalytic method for generating H2 starting from liquid water or vapour using said materials.
The present invention relates to metal-organic frameworks (MOFs) which contain trimetallic centres with pyrazole as a ligand in the structure thereof. Particularly, it relates to MOFs which contain units of formula (I). The present invention also relates to a photocatalytic method for generating H2 starting from liquid water or vapour using said materials.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
UNIVERSITE PARIS CITE (France)
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MEDICALE (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Aider, Jean-Luc
Jeger-Madiot, Nathan
Peyrin, Jean-Michel
Hoyos, Mauricio
Dupuis, Chloé
Abrégé
The invention relates to a device and method for assembling objects (11, 12) by generating an axial acoustic radiation force in order to position the objects (11, 12) on pressure nodes (N1-N4) and/or antinodes and generating a transverse acoustic radiation force in order to move the thus positioned objects (11, 12) on a porous membrane contact structure (4).
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
B01D 21/28 - Dispositifs mécaniques auxiliaires pour accélérer la sédimentation, p. ex. par des vibrateurs
52.
METHOD FOR SPATIAL TRACING AND SEQUENCING OF CELLS OR ORGANELLES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Blivet-Bailly, Gaël
Griffiths, Andrew
Ibanez, Pablo
Nghe, Phillipe
Rondelez, Yannick
Abrégé
The present invention concerns a labelling solution on or into a biological sample which allows identification tags to be assigned to areas of the biological sample comprising a single or plurality of cells or organelles, e.g. about two to ten cells.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
GOLD STANDARD DIAGNOSTICS MILLIDROP (France)
FONDATION DE COOPERATION SCIENTIFIQUE - PARIS SCIENCES ET LETTRES PSL VALORISATION (France)
Inventeur(s)
Boitard, Laurent
Cottinet, Denis
Balzan, Riccardo
Baudry, Jean
Chenon, Ghilhem
Goldstein, Arthur
Ferhout, Hicham
Abrégé
The method comprises the following steps: —providing particles (49) to be solubilised in stable suspension, the particles (49) of a suspension being of identical chemical composition; —generating at least one drop (16) comprising at least one particle (49) to be solubilised of the stable suspension of particles (49) and a culture medium (50) that is able to contain at least one living cell (4) and/or at least one product derived from a living cell in suspension; —introducing the drop (16) into a tube (10); —incubating the drop (16) in the tube (10); —illuminating the tube (10) through an incident light beam; and —measuring, at various times, the quantity of light from the light beam scattered transversely to the incident beam by the drop (16) in the tube (10).
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Soysal, Ugur
Nieckele Azevedo, Pedro
Tabeling, Patrick
Gaziola De La Torre, Lucimara
Costa Silva Noronha Pessoa, Amanda
Da Silveira Carvalho, Marcio
Martin, Elian
Abrégé
The present invention to freeze-dried monodisperse microbubbles. The invention also relates to a process for preparing said microbubbles using microfluidic techniques. The microbubbles according to the present invention show interesting properties, making them particularly useful in applications that require monodispersity of the microbubbles.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Nghe, Philippe
Kowsari-Esfahan, Reza
Griffiths, Andrew
Abrégé
The present invention relates to a microfluidic device for generating combinatorial spatially controllable diffusive gradients and methods for its manufacture. The present invention also relates to the uses of the microfluidic device of the invention and to the methods which it enables to implement.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
56.
MICROFLUIDIC DEVICE FOR GENERATING COMBINATORIAL SPATIALLY CONTROLLABLE DIFFUSIVE GRADIENTS
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Nghe, Philippe
Kowsari-Esfahan, Reza
Griffiths, Andrew
Abrégé
The present invention relates to a microfluidic device for generating combinatorial spatially controllable diffusive gradients and methods for its manufacture. The present invention also relates to the uses of the microfluidic device of the invention and to the methods which it enables to implement.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Aubry, Jean-François
Tiennot, Thomas
Tanter, Mickael
Abrégé
Nowadays, the interest to use ultrasound waves in medical field is well established. Such ultrasound waves may be focused for treating a zone in an organ such as the brain for instance. The focus allows to treat only the zone relative to the disease and avoid treating a healthy zone. Therefore, it is mandatory to use an image guidance system to monitor in real time where the ultrasound waves are focused. The guidance can be performed by Magnetic Resonance Imaging (MRI), Ultrasound Imaging (echography), or Optical Imaging (neuronavigation). However, such systems increase the cost and the complexity of the whole process. The present disclosure overcomes the above drawbacks by proposing a self-positioning acoustic lens allowing to ensure good ultrasound waves transmission in the zone to treat without requiring to the use of a navigation system.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE-INSERM (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE HOSPITALIER NATIONAL D'OPHTALMOLOGIE DES QUINZE-VINGTS (France)
Inventeur(s)
Grieve, Kate
Thouvenin, Olivier
Monfort, Tual
Azzollini, Salvatore
Reichman, Sacha
Abrégé
The invention relates to a module intended to be associated with a microscope for full-field optical coherence tomography microscopic imaging of at least one sample, the module comprising an interference device (4) comprising a non-polarising beam-splitter element (10) allowing two arms to be formed when illuminated by a source, i.e. a "reference arm" associated with the reflecting surface and an "object arm" associated with the sample, the device further comprising: - a first adjustment unit (11) arranged upstream of the non-polarising beam-splitter element so as to be able to modify an illumination arm of the non-polarising beam-splitter element during operation, and/or - at least one second adjustment unit (18) arranged between the beam-splitter element and the reflecting surface so as to be able to modify the reference arm during operation.
G01S 7/539 - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe utilisant l'analyse du signal d'écho pour la caractérisation de la cibleSignature de cibleSurface équivalente de cible
60.
A METHOD FOR DETERMINING THE VELOCITY OF A NATURAL SHEAR WAVE PROPAGATING IN A MEDIUM
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Papadacci, Clément
Pernot, Mathieu
Tanter, Mickael
Abrégé
Nowadays, the interest to use ultrasound waves in medical field is well established. Indeed, the study of mechanical waves propagating in a medium allows usually to retrieve the properties of this medium as an organ such the heart. These elastic properties may be determined on the basis of propagation parameters as the velocity of shear waves propagating in the medium. The shear waves may be generated artificially or naturally (e.g. valves closure of the heart) in the medium. In both cases, the generation or/and observation of such shear waves require high complex and cost system as well as complex method for estimating with high precision the velocity of shear. The present disclosure overcomes the above drawbacks by proposing a new method and detection system for estimating in a simple and efficiency way the velocity of shear waves propagating in a medium, and with a high precision, requirement needed for determining the elastic properties of the medium.
A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
G01S 7/539 - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe utilisant l'analyse du signal d'écho pour la caractérisation de la cibleSignature de cibleSurface équivalente de cible
61.
DEVICES AND METHODS BASED ON ULTRASOUNDS FOR RESTORING VISION OR ANY OTHER BRAIN FUNCTION
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
Inventeur(s)
Picaud, Serge
Cadoni, Sara
Sahel, José-Alain
Tanter, Mickaël
Demene, Charlie
Abrégé
Devices and methods for reversibly stimulating neuronal cells in a subject. The devices include a module for generating ultrasounds at 4 MHz or more to stimulate neuronal cells expressing mechanosensitive channels with the ultrasounds. The methods include expressing mechanosensitive channels into neuronal cells and exposing the cells to ultrasounds at 4 MHz or more. Also, the use of the methods or devices for visual restoration in a subject.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITE (France)
ÉCOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES (France)
Inventeur(s)
Robert, Clément
Magdelaine-Guillot De Suduirau, Quentin
Monteux, Cécile
Maillaud, Laurent
Mondiot, Frédéric
Abrégé
The invention relates to a method for coating a transparent substrate comprising the application to the substrate of an aqueous composition comprising a coating precursor and a surfactant having a critical minimum concentration of less than 1 mM or having a relaxation time of greater than or equal to 1 s. The invention also relates to the material obtained according to the method and to the use thereof as glazing.
C03C 17/28 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des matières organiques
C03C 17/30 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des matières organiques avec des composés contenant du silicium
C03C 17/32 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des matières organiques avec des résines synthétiques ou naturelles
63.
METHOD AND APPARATUS FOR ULTRASONIC EVALUATION OF AN ISOLATED ORGAN
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (France)
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
Inventeur(s)
Pernot, Mathieu
Tanter, Mickael
Demeulenaere, Oscar
Papadacci, Clément
Pereira Pedreira, Olivier
Ferrera, René
Abrégé
Organ transplantation remains the only definitive therapeutic solution for many pathologies, but the number of currently available grafts is largely insufficient. A new approach is proposed to quantitatively evaluate isolated organs by ultrasound, which enables to safely admit more isolated organs as grafts available for transplantation. The isolated organ (2) is received in an organ preservation container (3) made of ultrasound transparent material, and the isolated organ is imaged by an ultrasound imaging probe (6) through the container (3). The ultrasound image of the isolated organ is used to determine a quantitative index representing viability of the isolated organ.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITE (France)
PARIS SCIENCES ET LETTRES (France)
Inventeur(s)
Harms, Fabrice
Levecq, Xavier
Fragola, Alexandra
Abrégé
55) of the filtering element, the scan of the filtering element being synchronized with said scan of the line of light in such a way as to obtain a superposition, at any given moment in time, of said filtering element and of said fluorescence image of the line of light.
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
SORBONNE UNIVERSITE (France)
UNIVERSITÉ PARIS CITÉ (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS (France)
Inventeur(s)
Provost, Jean
Garofalakis, Anikitos
Pernot, Mathieu
Tanter, Mickaël
Tavitian, Bertrand
Viel, Thomas
Abrégé
The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a γ-ray, and c) determining the at least one property of the object based on the first data and the second data.
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
UNIVERSITE DU MANS (France)
BLUERIUM (France)
Inventeur(s)
Robert, Emmanuel
Abrégé
A method of attenuating the amplitude of waves having a given center wavelength, the method including the use of a device including: an assembly of a plurality of modules juxtaposed next to each other along a given direction, each module including at least one cavity having a first opening and a second opening; wherein the modules are placed in a position in which the first opening of each cavity is permanently submerged and the second opening is in communication with the ambient air, the dimensions of the cavities being determined so that each cavity forms a resonant cavity at the given center frequency.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN, INSTITUTE AMOLF (Pays‑Bas)
UNIVERSITEIT LEIDEN (Pays‑Bas)
Inventeur(s)
Singh, Amitesh
Labousse, Mathieu
Van Hecke, Martin
Abrégé
The invention relates to a device implementing a finite state machine, the device including a plurality of cells (Ci), each cell comprising a default bias selected among two opposite biases; a current state set among a released state (RS) and two activated states (LF, RF) respectively corresponding to the two opposite biases; a control input (Ai, Ai1, Ai2) for switching the current state of the cell between the released state and the activated state corresponding to a current bias of the cell; and a bias link (BHi) coupling the cell to an adjacent cell (Ci+1) of the plurality of cells, and setting the current bias of the cell to the current or default bias of the adjacent cell when the adjacent cell is in one of the two activated states, and setting the current bias of the cell to the default bias of the cell when the adjacent cell is in the released state.
H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
G09C 1/00 - Appareils ou méthodes au moyen desquels une suite donnée de signes, p. ex. un texte intelligible, est transformée en une suite de signes inintelligibles en transposant les signes ou groupes de signes ou en les remplaçant par d'autres suivant un système préétabli
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
MUSEUM NATIONAL D'HISTOIRE NATURELLE (France)
ECOLE NORMALE SUPERIEURE (France)
Inventeur(s)
Serre, Christian
Pimenta, Vanessa
Tignol, Pierre
Lavedrine, Bertrand
Dupont, Anne-Laurence
Abrégé
The invention relates to a method for preparing a porous membrane, the method comprising the following steps: apreparing an aqueous mixture comprising a dispersion of fibres from a water-based organic material, a solid organic binder and porous solid particles suspended in water; b- stirring the aqueous mixture comprising the fibres, the organic binder and the porous solid particles for at least 10 minutes at room temperature; c- vacuum filtering the mixture and recovering a composite material; and d- pressing the composite material obtained in step c- to form a porous membrane.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
MUSEUM NATIONAL D'HISTOIRE NATURELLE (France)
ECOLE NORMALE SUPERIEURE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Tignol, Pierre
Dupont, Anne-Laurence
Pimenta, Vanessa
Serre, Christian
Lavedrine, Bertrand
Abrégé
The invention relates to a method for preparing a porous membrane, the method comprising the following steps: a- preparing an aqueous mixture comprising a dispersion of fibres from a water-based organic material, a solid organic binder and porous solid particles suspended in water; b- stirring the aqueous mixture comprising the fibres, the organic binder and the porous solid particles for at least 10 minutes at room temperature; c- vacuum filtering the mixture and recovering a composite material; and d- pressing the composite material obtained in step c- to form a porous membrane.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Chazelas, Jean
Tripon-Canseliet, Charlotte
Abrégé
A metasurface device includes a ground structure able to have a ground plane function, the ground structure being able to be alternately in an insulating state, wherein it prevents the propagation of the surface wave over the front surface of a substrate so as to prevent the antenna element from radiating, and in a conductive state, wherein the ground structure has the ground plane function, allowing the propagation of the surface wave over the front surface of the substrate from the emission/reception device to the conductive patches, or vice versa, the ground structure being able to change from the insulating state to the conductive state through illumination of the ground structure at a wavelength called a switching wavelength.
H01Q 15/00 - Dispositifs pour la réflexion, la réfraction, la diffraction ou la polarisation des ondes rayonnées par une antenne, p. ex. dispositifs quasi optiques
H01Q 3/24 - Dispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier l'orientation, par commutation de l'énergie fournie, d'un élément actif rayonnant à un autre, p. ex. pour commutation du lobe
H01Q 3/26 - Dispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la phase relative ou l’amplitude relative et l’énergie d’excitation entre plusieurs éléments rayonnants actifsDispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la distribution de l’énergie à travers une ouverture rayonnante
71.
METHOD AND APPARATUS FOR IMAGING VASCULAR ACTIVITY DYNAMICALLY AT A MICROSCOPIC SCALE
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Tanter, Michael
Deffieux, Thomas
Renaudin, Noémi
Demené, Charlie
Abrégé
Method for imaging vascular activity dynamically at a microscopic scale in a vascular network of a human or animal, the method including: (a) performing a temporal series of Ultrasound Localization Microscopy images of a region of the vascular network, to obtain values of a vascular dynamics parameter in an area of interest in the region, a recording period of the temporal series of ULM images corresponding to a dynamical event, due to a cause other than cardiac pulsatily, which activates the vascular network in the region; (b) computing, based on the values of the vascular dynamics parameter, a measure of an evolution of the vascular dynamics parameter in response to the dynamical event.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Chazelas, Jean
Tripon-Canseliet, Charlotte
Abrégé
A metasurface device includes an antenna element formed on the front surface of a substrate, the antenna element comprising a two-dimensional array of electrically conductive patches spaced from one another and having dimensions smaller than the operating wavelength of an emission and/or reception device, the antenna element being able to radiate in a direction having a component perpendicular to the front surface of the substrate when the ground structure has a ground plane function, the substrate comprising a layer, called a connection layer, made of photoconductive semiconductor material, in direct physical contact with the conductive patches, the semiconductor material being insulating when it is not illuminated and able to be conductive when it is illuminated at a reconfiguration wavelength.
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
Centre National de la Recherche Scientifique (CNRS) (France)
Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (France)
Inventeur(s)
Pernot, Mathieu
Tanter, Mickael
Papadacci, Clément
Demeulenaere, Oscar
Abrégé
The present invention relates to the field of ultrasounds and imagining of the coronary blood flow of the heart. Patients with coronary microvascular dysfunction (CMD) have poor prognostic with significantly higher rates of cardiovascular events, including hospitalization for heart failure, sudden cardiac death, and myocardial infarction (MI). Despite the urgent clinical need, there are no non-ionizing and non-invasive techniques available in clinic to directly visualize the coronary microvasculature and assess the local coronary microvascular system. Flow imaging remains a difficult task to perform in the heart because of the fast movements of this organ. In order to overcome the limitations of actual imaging methods for the coronary blood flow, the inventors proposed an ultrasound ultrafast imaging method that automatically detect the time periods in which the myocardium velocity is low and estimate the coronary flow velocity and the tissue velocity from the same data acquisition.
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Tabeling, Patrick
Garneret, Pierre
Martin, Elian
Coz, Etienne
Brient-Litzler, Elodie
Manuguerra, Jean-Claude
Vanhomwegen, Jessica
Abrégé
A portable diagnostic device for performing the diagnosis of pathogens, such as viruses, bacteria, microorganisms, etc., by rapidly detecting their nucleic acids in a biological sample to be tested. Also, the use of the portable diagnostic device and the methods for detection of at least one nucleic acid sequence of interest implemented with the aid of the portable diagnostic device.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
75.
METAL ORGANIC FRAMEWORKS FOR THE SELECTIVE CAPTURE OF VOLATIL ORGANIC COMPOUNDS COMPRISING CARBOXYLIC ACID FUNCTIONAL GROUP(S) AND/OR VOLATILE ALCOHOLS
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE NORMALE SUPERIEURE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
INSTITUTO SUPERIOR TECNICO (Portugal)
Inventeur(s)
Severino Neves, Maria Inès
Serre, Christian
Nouar, Farid
Pinto, Moisès
Al Mothar, Abeer
Freitas, Catia
Abrégé
The present invention relates, inter alia, to the use of porous crystalline solids constituted of a metal-organic framework (MOF) for the selective capture of volatile organic compounds (VOCs) comprising carboxylic acid functional group(s) and/or volatile organic compounds (VOCs) comprising an hydroxyl functional group. The MOF solids of the present invention can be used for the purification of air, for example for the selective capture of VOCs comprising carboxylic acid functional group(s) and/or volatile organic compounds (VOCs) comprising an hydroxyl functional group from outdoor air. It may be used for art preservation, such as the conservation of cellulose derivate films, for indoor air purification systems such as HERA air filters, adsorbent purifiers, kettle filters, fette filters, honeycomb filters or air conditioning filters, for outdoor air purification systems such as gas mask, nose filter, adsorption columns or chimney filters, and in cosmetic applications such as deodorants, anti-odor shampoo, hygienic protection products, wipes or diapers.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
76.
Method and system for detecting receivers, and adjustable receiver
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Lerosey, Geoffroy
Abrégé
A method for detecting receivers includes a step of detecting a receiver, in which step a general controller detects an adjustable receiver when a general antenna receives a secondary wave emitted by the adjustable receiver, followed by a reconfiguration step in which the general controller commands a controller of the detected adjustable receiver to switch to an interaction mode in which the impedance of the adjustable receiver is alternated between a first configuration impedance and a second configuration impedance in order to detect other receivers. The reconfiguration step is of a duration that is an order of magnitude higher than the duration of each alternation of the first and second configuration impedances.
G06K 7/10 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation électromagnétique, p. ex. lecture optiqueMéthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLE DE LA VILLE DE PARIS (France)
Inventeur(s)
Brutt, Cecile
Gerardin, Benoit
Aubry, Alexandre
Derode, Arnaud
Prada, Claire
Abrégé
A device, for non-destructive testing of a mechanical part made of a polycrystalline material, includes: an ultrasonic probe including a two-dimensional array of transducers capable of emitting and receiving signals at different excitation angles; and a processing module suitable for controlling the emission and the reception of the transducers, for processing the signals received by the transducers so as to express the signals received by the ultrasonic probe in two planar wave planes constructed from the emission and reception wave vectors of the probe, and for deducing therefrom information representative of the three-dimensional orientation of the fiber structure of the mechanical part.
École Supérieure de Physique et de Chimie Industrielles (France)
Inventeur(s)
Pushp, Aakash
Mueed, M A
Madon, Benjamin
Arellano, Noel
Lionti, Krystelle
Wallraff, Gregory Michael
Fong, Anthony Bock
Hughes, Brian Peter
Ouazan-Reboul, Vincent
Abrégé
Forming a hardmask layer for reactive ion etching includes depositing a hardmask above an underlayer. The hardmask includes a layer of magnesium oxide having a thickness of up to 10 nm. A resist layer is deposited above the hardmask and developed to form a pattern that exposes portions of the hardmask. The pattern is transferred from the resist layer to the hardmask by rinsing exposed portions of the hardmask with a deionized water solution.
H01L 21/027 - Fabrication de masques sur des corps semi-conducteurs pour traitement photolithographique ultérieur, non prévue dans le groupe ou
H01L 21/033 - Fabrication de masques sur des corps semi-conducteurs pour traitement photolithographique ultérieur, non prévue dans le groupe ou comportant des couches inorganiques
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Tanter, Mickael
Deffieux, Thomas
Lebrin, Franck
Morisset, Clémentine
Abrégé
Functional imaging, in particular functional ultrasound imaging, is becoming a powerful tool for early detection of disorders such as neurodegenerative diseases. The present disclosure proposes a reliable method for such early detection, by delivering a stimulus to the nervous system, performing a functional imaging of an area of interest of the nervous system activated by the stimulus to obtain a series of hemodynamic Doppler images of the vascular network in the area of interest, and computing, from the series of hemodynamic Doppler images, a hemodynamic response (22) to the stimulus. The shape of hemodynamic response may be used to detect health disorders.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
SORBONNE UNIVERSITE (France)
UNIVERSITE PARIS CITE (France)
Inventeur(s)
Dupuis, Chloé
Aider, Jean-Luc
Peyrin, Jean-Michel
Hoyos, Mauricio
Abrégé
The invention relates to a technique for moving various objects such as cells (6) and particles (7) of hydrogel or a compressible material, suspended in a fluid (5), so as to form a layered structure akin to human organ tissue. A standing sound wave (4) is propagated through the fluid (5) so as to position the cells (6) on a pressure node and the particles on a pressure antinode. As such, the cells (6) have a positive acoustic contrast relative to the fluid (5), while the particles (7) have a negative acoustic contrast relative to the fluid (5).
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
PARIS SCIENCES LETTRES (France)
Inventeur(s)
Colin, Annie
Brahmi, Youcef
Abrégé
The invention relates to a cell (10) for a power generation device (1), which comprises: - two compartments (100, 101) intended respectively to receive fluids (F1, F2) that each have a different concentration of a predetermined ion, which compartments are separated by a membrane (105) allowing the predetermined ion to pass through; and - two adsorbent layers (107) of the predetermined ion placed respectively on either side of the membrane. The invention also relates to two power generation devices incorporating such a cell, and to a method for operating one of these devices.
H01M 8/18 - Éléments à combustible à régénération, p. ex. batteries à flux REDOX ou éléments à combustible secondaires
H01M 8/22 - Éléments à combustible dans lesquels le combustible est à base de matériaux comprenant du carbone, de l'oxygène ou de l'hydrogène et d'autres élémentsÉléments à combustible dans lesquels le combustible est à base de matériaux comprenant uniquement des éléments autres que le carbone, l'oxygène ou l'hydrogène
82.
A Full-Field Optical Coherence Tomography Imaging Method
Centre National de la Recherche Scientifique (CNRS) (République de Corée)
Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris (France)
Inventeur(s)
Mazlin, Viacheslav
Baracal De Mece, Pedro Francisco
Boccara, Albert Claude
Abrégé
A full-field optical coherence tomography imaging method, FFOCT, using a system comprising an FFOCT device and a sample, the sample comprising a layer of interest to be imaged, the FFOCT device comprising an incoherent light source, an imager, a beam splitter defining a sample arm and a reference arm, the method comprising-generating sample light containing interest light originating from the layer of interest and reference light traveling from the reference arm, —acquiring an image from reference light and sample light combined in the beam splitter; wherein at least one of the sample arm and the reference arm comprises an optical curvature compensator that modifies a transverse variation distribution of an optical path length to match the transverse variation distributions of the optical path lengths travelled by the reference light and the interest light incident on the imager.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (France)
UNIVERSITE DE LILLE (France)
CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE LILLE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Buee, Luc
Hamdane, Malika
Blum, David
Derisbourg, Maxime
Leghay, Coline
Chiappetta, Giovanni
Vinh, Joelle
Verdier, Yann
Abrégé
The invention relates to the identification of a new Tau species starting at residue Met11 (Met11-Tau) which is N-alpha-terminally acetylated form (N-alpha-acetyl-Met11-Tau species: Ac-Met11-Tau). Several monoclonal antibodies specific of this new Tau species have been developed. One of this antibody, 2H2/D11, was used in THY-Tau22 mouse model (that develops with age neurofibrillary degeneration (NFD) and memory deficits), and N-alpha-Ac-Met11-Tau species were clearly detected early in neurons displaying NFD on hippocampal brain sections while it is not reactive in hippocampus from elderly controls. Finally, by using ELISA sandwich specific of Ac-Met11-Tau species, Alzheimer Disease (AD) brain samples are clearly discriminated from human elderly control brains. Thus the invention relates to this new Tau species starting from the methionine residue at position 11 said methionine being N-alpha acetylated. The invention also relates to antibody that specifically binds this new tau species, a method of detection of this new Tau species and a method of diagnosis of Tauopathy disorder.
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
C07K 16/18 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
84.
CELL FOR POWER GENERATION DEVICE, ASSOCIATED DEVICES AND METHOD
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Colin, Annie
Brahmi, Youcef
Abrégé
The invention relates to a cell (10) for a power generation device (1), which comprises: - two compartments (100, 101) intended respectively to receive fluids (F1, F2) that each have a different concentration of a predetermined ion, which compartments are separated by a membrane (105) allowing the predetermined ion to pass through; and - two adsorbent layers (107) of the predetermined ion placed respectively on either side of the membrane. The invention also relates to two power generation devices incorporating such a cell, and to a method for operating one of these devices.
H01M 8/22 - Éléments à combustible dans lesquels le combustible est à base de matériaux comprenant du carbone, de l'oxygène ou de l'hydrogène et d'autres élémentsÉléments à combustible dans lesquels le combustible est à base de matériaux comprenant uniquement des éléments autres que le carbone, l'oxygène ou l'hydrogène
H01M 8/18 - Éléments à combustible à régénération, p. ex. batteries à flux REDOX ou éléments à combustible secondaires
85.
MOLECULAR IMPRINTED POLYMER AND USE THEREOF IN QUANTIFYING A PESTICIDE IN A SAMPLE
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
PARIS SCIENCES ET LETTRES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
AGENCE NATIONALE DE SECURITE SANITAIRE DE L'ALIMENTATION DE L'ENVIRONNEMENT ET DU TRAVAIL (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Pichon, Valérie
Combes, Audrey
Bosman, Pauline
Lavison-Bompard, Gwenaelle
Lambert, Marine
Abrégé
The present invention relates to a molecular imprinted polymer (MIP) in which the polymer is poly(4-vinylpyridine), or poly(2-vinylpyridine), cross-linked by a cross-linking agent, the molecular imprinted polymer being imprinted by chlordecol and containing imprint sites for chlordecol and/or chlordecone. The invention also relates to the use of the molecular imprinted polymer to purify a sample comprising chlordecone and/or chlordecol.
B01D 15/38 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction spécifique non couverte par un ou plusieurs des groupes , p. ex. chromatographie d'affinité, chromatographie d'échange par ligand ou chromatographie chirale
A01N 43/92 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'halogène comme hétéro-atomes du cycle
C08F 226/06 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et l'un au moins étant terminé par une liaison simple ou double à l'azote ou par un hétérocycle contenant de l'azote par un hétérocycle contenant de l'azote
86.
DEVICE AND METHOD FOR CENTIMETRE-LEVEL POSITIONING OF A MOVING OBJECT
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Hole, Stéphane
Ditchi, Thierry
Lucas, Jérôme
Geron, Emmanuel
Abrégé
The positioning system (9) comprises a device (10) and a plurality of fixed bases (12), which comprise a counter cyclically scanning n positions of the pointer. The device comprises a transmitter configured to transmit a request comprising at least one pattern of points, the values read with the pointer of which modulate a carrier. Each receiving base transmits a response: a) repeating the pattern received by the base from the device, and/or b) representative of a first pattern time offset, measured by the base, between the received pattern and an identical pattern stored in the memory of the base. The device comprises: - a means for measuring a second pattern time offset between the point values of the pattern received in each response and the values stored in the memory of the device, - a means for determining the distance between the device and each base according to: a) the total pattern offset between the pattern transmitted by the device and the repeated pattern received by the device from the base, and/or b) the second pattern offset and the first pattern offset measured by the base.
G01S 5/14 - Localisation par coordination de plusieurs déterminations de direction ou de ligne de positionLocalisation par coordination de plusieurs déterminations de distance utilisant les ondes radioélectriques déterminant des distances absolues à partir de plusieurs points espacés d'emplacement connu
G01S 13/82 - Systèmes utilisant la reradiation d'ondes radio, p. ex. du type radar secondaireSystèmes analogues dans lesquels des signaux de type continu sont transmis
G01S 13/84 - Systèmes utilisant la reradiation d'ondes radio, p. ex. du type radar secondaireSystèmes analogues dans lesquels des signaux de type continu sont transmis pour la détermination de distance par mesure de phase
G01S 13/87 - Combinaisons de plusieurs systèmes radar, p. ex. d'un radar primaire et d'un radar secondaire
G01S 5/00 - Localisation par coordination de plusieurs déterminations de direction ou de ligne de positionLocalisation par coordination de plusieurs déterminations de distance
G01S 11/02 - Systèmes pour déterminer la distance ou la vitesse sans utiliser la réflexion ou la reradiation utilisant les ondes radioélectriques
87.
METHOD FOR PREPARING A CRYSTALLINE POROUS ALUMINUM TETRACARBOXYLATE OF MOF TYPE, AND USES THEREOF
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE NORMALE SUPERIEURE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Serre, Christian
Mouchaham, Georges
Chen, Bingbing
Abrégé
4810822n48108222O} (x≥0), in the separation/capture of molecules having a size of less than 5 A, notably in the separation of molecules governed (i) by specific interactions with the groups -OH, -CO2H and/or -CO2- present on the surface of the pores of said MOF and/or (ii) by size exclusion by favoring the selective adsorption of molecules having sizes smaller than those of the pores of said MOF.
C07C 51/41 - Préparation de sels d'acides carboxyliques par conversion de ces acides ou de leurs sels en sels ayant la même partie acide carboxylique
B01D 15/00 - Procédés de séparation comportant le traitement de liquides par des adsorbants ou des absorbants solidesAppareillages pour ces procédés
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01J 31/16 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des complexes de coordination
École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (France)
Centre National de la Recherche Scientifique (France)
Sorbonne Université (France)
Université Paris Cité (France)
Inventeur(s)
Lindner, Anke
Ducloué, Lucie
Haque, Md. Anamul
Gong, Jian-Ping
Abrégé
The present invention relates to microfluidic or millifluidic chips (1) comprising at least one pressure sensing unit (4) able to measure a fluid flow pressure. The present invention also relates to a method for a direct and contact-free measuring of a local pressure of a fluid circulating in a microfluidic circuit, using a microfluidic or millifluidic chips (1) according to the invention.
G01L 9/00 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pressionTransmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent
G01L 27/00 - Test ou étalonnage des appareils pour la mesure de la pression des fluides
89.
REGENERABLE VOC FILTERS WITH IMPROVED SELECTIVITY AND EFFICACY
École Nationale Supérieure d'Ingénieurs de Caen (France)
Université de Caen Normandie (France)
Centre National de la Recherche Scientifique (France)
École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (France)
École Normale Supérieure de Paris (France)
TEQOYA SAS (France)
Inventeur(s)
Daturi, Marco
Guitton, Pierre
Nouar, Farid
Sadovnik, Nicolas
Serre, Christian
Abrégé
The present invention relates, inter alia, to the use of porous crystalline solids constituted of a metal-organic framework (MOF) for the selective adsorption of aldehyde volatile organic compounds.
The present invention relates, inter alia, to the use of porous crystalline solids constituted of a metal-organic framework (MOF) for the selective adsorption of aldehyde volatile organic compounds.
The MOF solids of the present invention can be used for the improved purification of dry or humid air, and for the manufacture of regenerable filters for air purification, particularly leak-free regenerable air filters.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01D 53/96 - Régénération, réactivation ou recyclage des réactifs
B01D 53/72 - Composés organiques non prévus dans les groupes , p. ex. hydrocarbures
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
B01J 20/20 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant du carbone libreCompositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant du carbone obtenu par des procédés de carbonisation
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Paulsen, Joseph, D.
Demery, Vincent
Abrégé
Thin elastic films that can spontaneously attach to liquid interfaces, thereby offering a platform for tailoring their physical, chemical, and optical properties. Curved shells can be used to manipulate interfaces in qualitatively different ways. For example, an ultrathin shell with vanishing bending rigidity can impose its own rest shape on a liquid surface, in a process where the pressure across the interface inflates the shell into its original shape. The approach is amenable to optical applications as the shell is transparent, free of wrinkles, and may be manufactured over a range of curvatures.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITE (France)
Inventeur(s)
Chazelas, Jean
Tripon-Canseliet, Charlotte
Ziaei, Afshin
Xavier, Stéphane
Abrégé
A radiating element of an antenna includes at least one wire-like nanostructure, each wire-like nanostructure extending in the same direction, called common direction, between a first end and a second end, and an inductor connected to each first end of a nanostructure, the inductor being formed from a first conductive material, the inductor extending in a plane normal to the common direction, the first conductive material having an electrical conductivity that varies under the effect of a variation of an electric field applied within the first conductive material.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Kamoun, Mohamed
Mokh, Ali
Khayatzadeh, Ramin
Ourir, Abdelwaheb
Derosny, Julien
Tourin, Arnaud
Fink, Mathias
Abrégé
The present disclosure relates to a wireless communication device for a wireless communication with two or more second wireless communication devices. The wireless communication device is configured to, for a channel between the wireless communication device and a respective second wireless communication device, initialize, based on a respective channel impulse response of the channel, a respective precoder for precoding a signal intended for the respective second communication device; determine one or more respective interference peaks caused at the respective second wireless communication device and/or at one or more other second wireless communication devices by transmitting a respective signal intended for the respective second wireless communication device and precoded by the respective precoder; select an interference peak fulfilling a criterion among the determined one or more respective interference peaks; and update, based on the selected interference peak, the respective precoder, which precodes the respective signal that causes the selected interference peak.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
PARIS SCIENCES ET LETTRES - QUARTIER LATIN (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Boccara, Albert Claude
Boccara, Martine
Thouvenin, Olivier
Abrégé
The present description relates to a three-dimensional imaging system (100) comprising a light source (110) configured to emit a beam of spatially incoherent light, having a given central length, configured to illuminate a biological sample (10) being transmitted; an optical imaging system (120) comprising a microscope lens (121) with a given object focal plane (125) near which the sample (10) is positioned; means for axially moving the microscope lens relative to the sample; a two-dimensional acquisition device (140) comprising a plurality of elementary detectors arranged in a detection plane (141) optically conjugate with the object focal plane and a processing unit (150). For each section of a biological object of the sample, a plurality of two-dimensional interferometric signals resulting from optical interference between the illumination beam and a beam scattered by an object field of the section are acquired and at least a first image is calculated from the plurality of two-dimensional interferometric signals.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
PARIS SCIENCES ET LETTRES (France)
Inventeur(s)
Gines, Guillaume
Rondelez, Yannick
Jet, Thomas
Taly, Valérie
Abrégé
The present invention relates to a digital multiplex method for detecting and/or quantifying multiple target biomolecules in a sample, said biomolecules being selected from DNA, RNA, and proteins. The present invention further relates to different applications of the digital multiplex method and to a kit.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Baudry, Jean
Bibette, Jérôme
Boitard, Laurent
Eyer, Klaus
Langer, Krzysztof
Abrégé
The present invention relates to a method for selecting and recovering products, including providing an emulsion (6) comprising a plurality of drops (4) contained in a carrier fluid (10), each drop comprising an internal fluid (8), measuring at least one physical parameter for several drops (4) of the emulsion (6), classifying at least some of the drops (4) of the emulsion in a class based on measurements obtained during measuring, tagging at least some of the classified drops (4) based on the class of the drop (4), and selectively recovering the drop (4) or part of the drop (4) using the tag of the drop or part of the drop (4).
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12Q 1/6804 - Analyse d’acides nucléiques utilisant des immunogènes
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
96.
Method for measuring the speed of sound in liver with a specific probe and associated methods and devices
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS (France)
UNIVERSITÉ PARIS CITÉ (France)
SORBONNE UNIVERSITÉ (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
Inventeur(s)
Pernot, Mathieu
Deffieux, Thomas
Tanter, Mickael
Papadacci, Clément
Abrégé
Because of the increase of the obesity related diseases, it is desirable to be able to detect a fatty liver and quantify the content in fat for the fatty liver. Known methods are biopsy and magnetic resonance imaging. However, biopsy is an invasive method and magnetic resonance imaging is a complicated method to carry out. The inventors propose a new ultrasonic method, which is more compliant with a regular control of the content in fat for the fatty liver for a subject. This method notably relies on a smart exploitation of the coherence properties of ultrasound pulses applied to the liver. This method has already been validated on sane subjects as providing accurate measurements, notably for fat content.
A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
G01S 7/52 - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe
G01S 15/89 - Systèmes sonar, spécialement adaptés à des applications spécifiques pour la cartographie ou la représentation
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
97.
A METHOD FOR MEASURING THE SPEED OF SOUND IN LIVER WITH A MOVING PROBE AND ASSOCIATED METHODS AND DEVICES
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITÉ (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIME INDUSTRIELES DE LA VILLE DE PARIS (France)
Inventeur(s)
Pernot, Mathieu
Deffieux, Thomas
Tanter, Mickael
Papadacci, Clément
Abrégé
Because of the increase of the obesity related diseases, it is desirable to be able to detect a fatty liver and quantify the content in fat for the fatty liver. Known methods are biopsy and magnetic resonance imaging. However, biopsy is an invasive method and magnetic resonance imaging is a complicated method to carry out. The inventors propose a new ultrasonic method which is more compliant with a regular control of the content in fat for the fatty liver for a subject. This method notably relies on a smart exploitation of the coherence properties of ultrasound pulses applied to the liver. This method has already been validated on sane subjects as providing accurate measurements, notably for fat content.
A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G01S 15/89 - Systèmes sonar, spécialement adaptés à des applications spécifiques pour la cartographie ou la représentation
98.
Pneumatic structure and associated production method
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
SORBONNE UNIVERSITÉ (France)
Inventeur(s)
Siefert, Emmanuel
Roman, Benoît
Bico, José
Reyssat, Etienne
Abrégé
The structure (10) comprises an elastically deformable body (12) defining at least one network of internal cavities (14), each internal cavity (14) having a closed contour in at least one section of the internal cavity (14).
Each internal cavity (14) is able to be pressurized so as to make the elastically deformable body (12) pass from a rest configuration to at least one pressurized configuration.
In each pressurized configuration, the elastically deformable body (12) has a macroscopic metric that is distinct from its macroscopic metric in the rest position.
In each pressurized configuration, the radius of curvature of an outer surface of the elastically deformable body (12), considered regarding each internal cavity (14) adjacent to the outer surface, is greater than twice the size of the internal cavity (14) adjacent to the outer surface.
F16F 9/04 - Ressorts, amortisseurs de vibrations, amortisseurs de chocs ou amortisseurs de mouvement de structure similaire, utilisant un fluide ou moyen équivalent comme agent d'amortissement utilisant un gaz uniquement dans une chambre à paroi flexible
99.
DIGITAL BIOMOLECULES DETECTION AND/OR QUANTIFICATION USING ISOTHERMAL AMPLIFICATION
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
PARIS SCIENCES ET LETTRES (France)
Inventeur(s)
Rondelez, Yannick
Gines, Guillaume
Lima De Castro Menezes, Roberta
Taly, Valérie
Abrégé
The present invention relates to a digital method for detecting and/or quantifying at least one target biomolecules in a sample, said biomolecules being selected from DNA, RNA, and proteins based on isothermal amplification. The present invention further relates to different applications of the digital method and to a kit.
C12Q 1/6848 - Réactions d’amplification d’acides nucléiques caracterisées par les moyens d’empêcher la contamination ou d’augmenter la spécificité ou la sensibilité d’une réaction d’amplification
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
100.
METHOD FOR CHARACTERIZING THE VIBRATION OF A SURFACE