Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Kumar, Sanjay S.
Beesley, Stephen
Abrégé
D-serine is effective for inhibiting neuron loss due to an immune response by glial cells to a brain injury. An example of a method includes artificially administering a composition including D-serine to brain cells after an injury thereto, the composition including an amount of D-serine effective to inhibit death of neurons.
A61K 31/198 - Alpha-amino-acides, p. ex. alanine ou acide édétique [EDTA]
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
2.
Methods and Compositions for Determining Salmonella Presence and Concentration Using PCR Primers of Varying Amplification Efficiencies
The Florida State University Research Foundation, Inc. (USA)
The United State of America, as presented by the Secretary of Agriculture (USA)
Inventeur(s)
Singh, Prashant
Bosilevac, Joseph M.
Abrégé
Disclosed herein are methods and kits for quantifying the presence of a microorganism in a sample. Specifically, disclosed are methods for quantifying a pathogen in a sample, such as a food sample, to determine if the levels of pathogen present in the sample are within an acceptable range.
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Bosque, Ernesto
Kolb-Bond, Dylan
Voran, Adam
Gavrilin, Andrey
Abrégé
A non-bonded, tape wound magnet includes a stack of disk coils, the disk coils having outer radius rd stacked on a z axis having opposing terminal ends. The disk coils include pancake-wound superconducting tape including a superconducting material and having a wound radius rsc. At least one disk coil at each opposing terminal end of the stack has overbanding positioned radially outward from the pancake wound superconducting tape. The overbanding has an elastic modulus and ultimate tensile strength at least 50% greater than the elastic modulus and ultimate tensile strength of the superconducting tape, and an electrical resistance at least 100% greater than that of the superconducting material, the overbanding having a radial dimension ro. The overbanding applies radial compression to the pancake wound superconducting tape. A method of making a magnet is also disclosed.
FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Nichols, David
Smith, Joel
Abrégé
The present disclosure relates in some aspects to substituted ergolines, such as 14-monosubstituted and 2,14-disubstituted lysergamides, and quaternized derivatives thereof. In some aspects, the disclosure relates to methods of synthesizing the compounds, compositions containing the compounds, and methods of using the compounds, including their administration to subjects. In some aspects, features of the compounds include neuromodulatory activity, for example, activation of serotonin receptors. In some further aspects, the compounds are useful as therapeutic agents, such as anti-inflammatory agents.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Pritchard, Emily
Barsoum, Mina-Michael
Delp, Judy
Maraj, Joshua
Abrégé
Various implementations include a method of decreasing oxygen saturation levels in a patient, including securing a leg and foot of the patient to a splint having a leg supporting portion, a foot supporting portion, and an inflatable device. The leg supporting portion includes a leg support body and leg support surface. The foot supporting portion includes a foot support body and foot support surface. The inflatable device rotates the foot support surface relative to the leg support surface from a first position to a second position. The angle between a leg longitudinal axis and a foot longitudinal axis is less in the second position than in the first position. The method further includes inflating the inflatable device to rotate the foot support surface from the first position to the second position and maintaining the second position to decrease oxygen saturation levels in the patient.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Alamdari, Nasrin
Abrégé
Disclosed herein are a system and methods for determining an area's vulnerability to waterborne diseases and evaluating stormwater best management practices (BMPs) to mitigate vulnerabilities, according to various implementations. Generally, the disclosed system is configured to obtain data relating to a number of waterborne disease cases in a given area and corresponding socioeconomic data for the area. Based on these datasets, the disclosed system can determine a vulnerability index that is indicative of the area's vulnerability to waterborne diseases. The system can then predict how various stormwater BMPs can impact the vulnerability index (e.g., positively or negatively) to evaluate how implementing stormwater BMPs can improve the subject area's vulnerability to waterborne diseases. In some cases, the system and methods described herein may be implemented via a software tool; however, other implementations are contemplated herein.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
7.
METAL-POLYMER INTERFACIAL BONDING TEST APPARATUS AND MANUFACTURING METHOD FOR EXTREME CONDITIONS
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Sweat, Rebekah
Cheetham, Peter Graham
De Leon, Ana
Abrégé
Various implementations described herein include methods and systems for characterizing material properties at cryogenic temperatures that are suitable for studying epoxy and metal interfaces. One implementation include a mold for forming composite samples for a pullout test. Various other implementations include a method of forming a composite sample for a pullout test.
G01N 3/08 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression
B29C 33/12 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens incorporés pour positionner des inserts, p. ex. marquages
B29C 33/38 - Moules ou noyauxLeurs détails ou accessoires caractérisés par la matière ou le procédé de fabrication
8.
Metal Halide Perovskites, Light-Emitting Diodes, and Methods
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ma, Biwu
Tian, Yu
Abrégé
Metal halide perovskite crystals, composite materials that include metal halide perovskite crystals and a polymeric matrix material, devices that include metal halide perovskite crystals, and methods of forming metal halide perovskite crystals, composite materials, and devices. The devices may include optoelectronic devices, such as light-emitting diodes. The light-emitting diodes may emit red light.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Clayton, Jessica Ridgway
Abrégé
A wearable clip system comprises a shoulder strap with a front portion comprising an upper section having two ends, wherein one end attaches to a back portion of the shoulder strap and a second end attaches to a first clip portion of a middle clip; a lower section having two ends, wherein one end attaches to a first clip portion of an end clip and a second end attaches to the first clip portion of the middle clip; and an additional strap section having two ends, wherein one end attaches to the back portion of the shoulder strap and a second end attaches to a second clip portion of the middle clip.
H01F 1/01 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriésEmploi de matériaux spécifiés pour leurs propriétés magnétiques en matériaux inorganiques
C22C 19/00 - Alliages à base de nickel ou de cobalt, seuls ou ensemble
C22C 19/07 - Alliages à base de nickel ou de cobalt, seuls ou ensemble à base de cobalt
C07D 205/04 - Composés hétérocycliques comportant des cycles à quatre chaînons ne contenant qu'un atome d'azote comme unique hétéro-atome du cycle non condensés avec d'autres cycles ne comportant pas de liaison double entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques
C07D 205/12 - Composés hétérocycliques comportant des cycles à quatre chaînons ne contenant qu'un atome d'azote comme unique hétéro-atome du cycle condensés avec des carbocycles ou avec des systèmes carbocycliques
C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
12.
LEAKAGE DETECTION IN SYRINGES AND SIMILAR SEAL SYSTEMS
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Delong, Adam
Krick, Brandon Alexander
Vanmeter, Kylie M. Elizabeth
Fidd, Catherine
Lazarte, Santiago
Abrégé
A prefilled syringe testing system may include an interface configured to fluidly couple with the cavity of the prefilled sealed container. A prefilled syringe testing system may include a vacuum pump providing a predetermined negative pressure to the interface. A prefilled syringe testing system may include a pressure gauge coupled to the interface and providing a pressure measurement indicative of leakage from the cavity.
G01M 3/32 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par mesure du taux de perte ou de gain d'un fluide, p. ex. avec des dispositifs réagissant à la pression, avec des indicateurs de débit pour récipients, p. ex. radiateurs
A61M 5/315 - PistonsTiges de pistonGuidage, blocage, ou limitation des mouvements de la tigeAccessoires disposés sur la tige pour faciliter le dosage
13.
SYSTEM AND METHOD FOR CONTINUOUS METABOLISM OF CONTAMINANTS OF EMERGING CONCERN
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Tang, Youneng
Abrégé
Described herein are systems and methods for continuous metabolism of contaminants of emerging concern. An example bioreactor can include at least one screen positioned downstream in relation to the at least one adsorbent layer, wherein: the bioreactor system is configured to retain within the housing the biofilm that becomes detached from the at least one adsorbent layer, the housing is configured to receive through the inlet a flow of an influent comprising water contaminated with the at least one target contaminant, and the bioreactor system is configured to discharge an effluent from the outlet, which comprises water with a lower concentration of the contaminant compared to the influent.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ma, Biwu
Zhou, Chenkun
Lin, Haoran
Tian, Yu
Abrégé
Bulk assemblies are provided, which may have desirable photoluminescence quantum efficiencies. The bulk assemblies may include two or more metal halides, and a wide band gap organic network. The wide band gap organic network may include organic cations. The metal halides may be disposed in the wide band gap organic network. Light emitting composite materials also are provided.
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
C09K 11/66 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du germanium, de l'étain ou du plomb
C09K 11/74 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant de l'arsenic, de l'antimoine ou du bismuth
C09K 11/77 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant des métaux des terres rares
H05B 33/14 - Sources lumineuses avec des éléments radiants ayant essentiellement deux dimensions caractérisées par la composition chimique ou physique ou la disposition du matériau électroluminescent
H05B 33/20 - Sources lumineuses avec des éléments radiants ayant essentiellement deux dimensions caractérisées par la composition chimique ou physique ou la disposition du matériau dans lequel le matériau électroluminescent est enrobé
15.
X-Ray Scintillators, Metal Halide Hybrids, Devices, and Methods
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ma, Biwu
Xu, Liang-Jin
He, Qingquan
Abrégé
Methods of scintillation, scintillation devices, and metal halide hybrids that may be used as X-ray scintillators. The metal halide hybrids may include organic metal halide hybrids, inorganic metal halide hybrids, or organic-inorganic metal halide hybrids. The metal halide hybrids may have a 0D structure. The metal halide hybrids may be in the form of one or more discrete crystals.
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Jaroszynski, Jan J.
Abrégé
An apparatus is provided for reel-to-reel assessment of superconducting tapes (for example, REBCO CC tape) at low temperatures (for example, less than or equal to 65K). For example, the apparatus may be a forced magnetometer. The apparatus may include one or more reels and pulleys used to move the superconducting tape into and out of a cryostat. The apparatus may also include a permanent magnet or electromagnet provided at a low temperature proximate to the tape. The magnet induces screening currents in the tape. The apparatus may also include an electric motor used to drive movement of the tape relative to the magnet. A tensionmeter may be provided to measure a tension of the tape. Alternatively, a current provided to the motor may also be measured. The apparatus may be used to measure the critical current at various positions on the superconducting tape at the low temperatures.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Chen, Gang
Abrégé
The present disclosure provides for a composition comprising a hydrochar, wherein the hydrochar comprises microwave-irradiated biomass. Further provided herein is a method of making the composition of claim 1, the method comprising: irradiating the biomass with microwaves under an inert atmosphere at conditions effective to yield the hydrochar. Also disclosed herein is a method of improving the quality of a soil comprising combining the soil with the composition disclosed herein.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Gubanov, Mikhail
Abrégé
Described herein are systems and methods providing online, interactive, trustworthy knowledge graphs for a specific topic (e.g., COVID-19) and search engines using such knowledge graphs. In some aspects, a method for automatically constructing knowledge graphs includes: accessing a dataset, the dataset including a plurality of articles related to a specific topic; classifying, using a first artificial intelligence (AI) model, a plurality of tables within the dataset; classifying, using a second AI model, a plurality of hierarchal metadata of the tables; and fusing, using a third AI model, the hierarchal metadata into a knowledge graph, the knowledge graph being associated with the specific topic.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Lazenby, Robert A.
Strouse, Geoffrey F.
Ritz, Amanda J.
Bertini, Isabella A.
Abrégé
For renewable energy technology to become ubiquitous, it is imperative to develop efficient oxygen evolution reaction (OER) electrocatalysts, which is challenging due to the kinetically and thermodynamically unfavorable OER mechanism. In accordance with the purpose(s) of the present disclosure, described herein are iron/nickel carbide compounds that possess unique electrochemical properties. The electrochemical performance of carbides can fine-tuned via Fe incorporation and with control, or suppression, of the growth of the oxide phase on the carbide catalytic surface.
C25B 11/075 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’un seul élément catalytique ou composé catalytique
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Lazenby, Robert A.
Strouse, Geoffrey F.
Ritz, Amanda J.
Bertini, Isabella A.
Abrégé
For renewable energy technology to become ubiquitous, it is imperative to develop efficient oxygen evolution reaction (OER) electrocatalysts, which is challenging due to the kinetically and thermodynamically unfavorable OER mechanism. In accordance with the purpose(s) of the present disclosure, described herein are iron/cobalt/nickel carbide compounds that possess unique electrochemical properties.
C25B 11/075 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’un seul élément catalytique ou composé catalytique
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Lupton, Joseph
Krick, Brandon Alexander
Abrégé
Described and disclosed herein are embodiments of a tribometer. In some instances the tribometer comprises an actuator system composed of a monolithic biaxial load cell with an integrated sample holder, a flexure, and an amplified piezo actuator.
G11C 11/44 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments électriques utilisant des éléments supraconducteurs, p. ex. des cryotrons
G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p. ex. couplage ou commande de qubit
G11C 11/16 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments magnétiques utilisant des éléments dans lesquels l'effet d'emmagasinage est basé sur l'effet de spin
23.
GLASSY ANTIFOULING COATINGS AND METHODS FOR MAKING AND USING THE SAME
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Akintola, John
Schlenoff, Joseph
Abrégé
Described herein are articles coated with one or more polyelectrolyte complexes. The polyelectrolyte complexes have a high glass transition temperature when the coating is contacted with an aqueous medium. In one aspect, the coating has a glass transition temperature of at least 45° C. when in contact with an aqueous medium, which makes the coatings described herein as “glassy.” The coating compositions described herein are effective in reducing adhesion of organisms on the surface of the coated article, which makes the coatings an effective antifouling coating.
C08F 212/14 - Monomères contenant un seul radical aliphatique non saturé contenant un cycle substitué par des hétéro-atomes ou des groupes contenant des hétéro-atomes
C08F 226/02 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et l'un au moins étant terminé par une liaison simple ou double à l'azote ou par un hétérocycle contenant de l'azote par une simple ou une double liaison à l'azote
C08F 226/06 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et l'un au moins étant terminé par une liaison simple ou double à l'azote ou par un hétérocycle contenant de l'azote par un hétérocycle contenant de l'azote
C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
C08G 65/26 - Composés macromoléculaires obtenus par des réactions créant une liaison éther dans la chaîne principale de la macromolécule à partir d'éthers cycliques par ouverture d'un hétérocycle à partir d'éthers cycliques et d'autres composés
C08G 65/40 - Composés macromoléculaires obtenus par des réactions créant une liaison éther dans la chaîne principale de la macromolécule à partir de composés hydroxylés ou de leurs dérivés métalliques dérivés des phénols à partir des phénols et d'autres composés
C08G 75/029 - Modification par des composés organiques
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Guo, Zhehui
Li, Hui
Abrégé
The disclosure relates to a devices, systems and methods implementing desaturation protection during faults (over-current or short-circuit faults) for a power device by monitoring drain source voltage and rate of change of the drain source voltage which provides a fault response time (t0 to t2) that is shorter than the blanking time (t0 to t5) required by conventional desaturation protection methods.
H03K 17/0812 - Modifications pour protéger le circuit de commutation contre la surintensité ou la surtension sans réaction du circuit de sortie vers le circuit de commande par des dispositions prises dans le circuit de commande
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Chung, Hoyong
Abrégé
An example of a bottlebrush polymer has a polymer backbone and a plurality of individual brush moieties bonded to the polymer backbone. The individual brush moieties respectively include a crosslinked oxyamine moiety, a hydrophilic segment, and a surface adhesive terminal group.
C08F 290/00 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères modifiés par introduction de groupes aliphatiques non saturés terminaux ou latéraux
C08F 290/02 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères modifiés par introduction de groupes aliphatiques non saturés terminaux ou latéraux sur des polymères modifiés par introduction de groupes non saturés terminaux
C08F 290/04 - Polymères prévus par les sous-classes ou
C08F 291/06 - Composés macromoléculaires obtenus par polymérisation de monomères sur des composés macromoléculaires prévus par plus d'un des groupes sur des macromolécules contenant de l'oxygène
C08F 291/12 - Composés macromoléculaires obtenus par polymérisation de monomères sur des composés macromoléculaires prévus par plus d'un des groupes sur des macromolécules contenant de l'azote
C08G 61/08 - Composés macromoléculaires contenant uniquement des atomes de carbone dans la chaîne principale de la molécule, p. ex. polyxylylènes uniquement des atomes de carbone aliphatiques préparés par ouverture du cycle des composés carbocycliques des composés carbocycliques contenant une ou plusieurs doubles liaisons carbone-carbone dans le cycle
C08G 65/333 - Polymères modifiés par post-traitement chimique avec des composés organiques contenant de l'azote
C08G 65/334 - Polymères modifiés par post-traitement chimique avec des composés organiques contenant du soufre
C08G 65/336 - Polymères modifiés par post-traitement chimique avec des composés organiques contenant du silicium
C08J 3/24 - Réticulation, p. ex. vulcanisation, de macromolécules
26.
VOLTAGE AND CURRENT-SENSING-LESS SHORT-CIRCUIT PROTECTION AND LOCALIZATION FOR POWER DEVICES
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Li, Hui
Guo, Zhehui
Abrégé
A short-circuit protection and localization circuit for power devices includes a first subcircuit for detecting dv/dt of a power device at turn on, a second subcircuit for short-circuit fault localization and soft turn-off of the power device, the second subcircuit including a totem-pole driver having an upper switch and a lower switch, and a third subcircuit for detecting short-circuit faults based on the output (Vdip) of the first subcircuit and the output of an upper switch (Vp) of the second subcircuit. The first subcircuit outputs a voltage (Vdip) having a magnitude that is proportional to dv/dt of the power device. The third subcircuit outputs a signal (Vsto) to the second subcircuit that causes the second subcircuit to softly turn-off the power device. The second subcircuit outputs a voltage of the upper switch (Vp) and a fault-latching signal for short-circuit localization.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Lazenby, Robert A.
Strouse, Geoffrey F.
Ritz, Amanda J.
Bertini, Isabella A.
Abrégé
For renewable energy technology to become ubiquitous, it is imperative to develop efficient oxygen evolution reaction (OER) electrocatalysts, which is challenging due to the kinetically and thermodynamically unfavorable OER mechanism. In accordance with the purpose(s) of the present disclosure, described herein are iron/cobalt carbide compounds. The electrochemical performance of carbides can fine-tuned via Fe incorporation and with control, or suppression, of the growth of the oxide phase on the carbide catalytic surface.
C25B 11/075 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’un seul élément catalytique ou composé catalytique
FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Gunjan, Akash
Son, Yuna
Abrégé
This disclosure relates to pharmaceutical compositions comprising one or more therapeutic agents selected from a SERPINE1 serine protease inhibitor, a histone acetyltransferase inhibitor, a histone deacetylase inhibitor, an insulin-like growth factor inhibitor, an anti-hypertensive agent, a topoisomerase II inhibitor, a tyrosine kinase inhibitor, an agent that downregulates growth factors or any combination thereof, and methods of treating fibrotic disorders, including keloid, pulmonary fibrosis, hepatic fibrosis, cardiac fibrosis, renal fibrosis, mediastinal fibrosis, retroperitoneal cavity fibrosis, bone marrow fibrosis, and/or scleroderma using the same. The disclosed methods can be accompanied by application of radiation and/or surgical resection. For treating keloids, the compositions can be formulated topically and do not cause systemic side effects. For treating fibrotic diseases of internal organs, the compositions can be administered systemically or delivered to the affected organs. The compositions can include two or more therapeutic agents that work synergistically, allowing lower doses of each therapeutic agent.
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/136 - Amines, p. ex. amantadine ayant des cycles aromatiques, p. ex. méthadone ayant le groupe amino lié directement au cycle aromatique, p. ex. benzène-amine
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61K 31/405 - Acides indole-alkanecarboxyliquesLeurs dérivés, p. ex. tryptophane, indométhacine
A61K 31/4418 - Pyridines non condenséesLeurs dérivés hydrogénés ayant un carbocycle lié directement à l'hétérocycle, p. ex. cyproheptadine
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Locke, Bruce R.
Wandell, Robert J.
Raja, Radha Krishna Bulusu
Abrégé
A method of conducting reactions utilizing a gas/liquid/plasma reactor includes the steps of providing a gas/liquid/plasma reactor, providing a liquid and a gas defining a gas/liquid interface within the gas/liquid/plasma reactor, and charging the liquid and gas inside the gas/liquid/plasma reactor. The charging includes the application of a voltage to electrodes and thereby to the liquid and gas which includes a series of voltage bursts having an outer burst pulse frequency. The bursts each include a series of voltage pulses having an inner burst pulse frequency. The electrodes can be oriented such that a plasma is propagated across the gas/liquid interface when the voltage pulses are applied. A system for conducting reactions utilizing a gas/liquid/plasma reactor is also disclosed.
FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Park, Chiwoo
Abrégé
Systems and methods are provided for image reconstruction of a sample via adaptive probing of piecewise continuous surfaces. A machine learning algorithm can be employed with scanning-based measurement instruments or experimental probers to optimize the selection of probe locations for effectively scanning piecewise continuous surfaces. A limited number of initial probes may first be obtained to estimate the piecewise continuous surface. The machine learning algorithm may then be leveraged to identify any subsequent probe locations used to obtain additional data points about the piecewise continuous surface. The selection of the probe locations may be performed iteratively until sufficient data has been obtained to generate an accurate image reconstruction.
G06T 5/60 - Amélioration ou restauration d'image utilisant l’apprentissage automatique, p. ex. les réseaux neuronaux
G06F 17/17 - Évaluation de fonctions par des procédés d'approximation, p. ex. par interpolation ou extrapolation, par lissage ou par le procédé des moindres carrés
31.
SELECTIVE TREATMENT OF CANCERS HAVING HISTONE H3 MUTATIONS OR ABERRANT LEVELS OF DNA OR HISTONE METHYLATION, ACETYLATION OR DEFECTS IN HOMOLOGOUS RECOMBINATION
FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Gunjan, Akash
Abrégé
The invention concerns compositions and a method for treating or delaying the onset, progression, or relapse of a cancer in a subject, the method comprising administering, optionally with radiation therapy, two or more of: a DNA-dependent protein kinase catalytic subunit (DNA-PKcs) inhibitor, a poly-ADP ribose polymerase (PARP) inhibitor, an isocitrate dehydrogenase (IDH) inhibitor, a histone acetyltransferase (HAT) inhibitor, a histone deacetylase (HDAC), inhibitor, and a DNA polymerase theta (POLθ) inhibitor. The inhibitors can be administered to the subject simultaneously, or sequentially in any order or combination.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Peng, Fang
Li, Hui
Abrégé
The disclosure relates to a devices, systems and methods implementing a delta-connected cascaded multilevel converter comprised of a plurality of U-PEBBs, each U-PEBB comprising a bi-directional and isolated ac to dc converter module using Si or SiC power semiconductor devices.
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
33.
ORGANIC METAL HALIDE HYBRIDS, ELECTRICALLY DRIVEN LIGHT EMITTING DIODES, AND METHODS
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Liu, He
Ma, Biwu
Abrégé
Organic metal halide hybrids (OMHHs) that can be used as improved materials (e.g., emitter materials) for electrically driven LEDs are provided, as well as methods of fabricating the same. The OMHHs can be highly luminescent and conductive zero-dimensional (0D) OMHHs. Efficient LEDs can include one or more of the OMHHs described herein. For example, the OMHH can be (and the LEDs can be based on) solution processed TPPcarzSbBr4 thin films and/or TPPcarzSbBr4 single crystals.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Kennemur, Justin G.
Abrégé
The present disclosure provides block copolymers, thin films including block copolymers, and methods for forming block copolymers and thin films. The block copolymers, due to self-assembly or otherwise, may include one or more regions. The one or more regions may permit a thin film including a block copolymer to be used as a nanostructured membrane.
C08F 293/00 - Composés macromoléculaires obtenus par polymérisation sur une macromolécule contenant des groupes capables d'amorcer la formation de nouvelles chaînes polymères rattachées exclusivement à une ou aux deux extrémités de la macromolécule de départ
C08F 220/18 - Esters des alcools ou des phénols monohydriques des phénols ou des alcools contenant plusieurs atomes de carbone avec l'acide acrylique ou l'acide méthacrylique
C08F 226/06 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et l'un au moins étant terminé par une liaison simple ou double à l'azote ou par un hétérocycle contenant de l'azote par un hétérocycle contenant de l'azote
C08F 228/02 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et l'un au moins étant terminé par une liaison au soufre ou par un hétérocycle contenant du soufre par une liaison au soufre
35.
SYSTEMS AND METHODS FOR ERROR REDUCTION IN THREE-DIMENSIONAL (3D) PRINTING
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Wang, Hui
Wei, An-Tsun
Abrégé
Systems and methods for error reduction in three-dimensional (3D) printing are provided and can include automatically adjusting printing parameters (for example, printing speed, acceleration, extrusion rate, and/or any other parameters) in the “G-codes” for a 3D printer (for example, fused deposition modeling) to compensate for printing errors that may occur when printing is performed at a high speed. An algorithm can be used to increase printing speed while mitigating reductions in printing quality.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Li, Yan
Abrégé
Extracellular vesicles (EVs) from human induced pluripotent stem cells (hiPSCs) may be produced by forming 3-D brain organoids of the hiPSCs in a dynamic bioreactor and collecting the EVs from the bioreactor. The EVs may be used for treating ischemic conditions.
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Jaroszynski, Jan J.
Abrégé
An apparatus is provided for reel-to-reel assessment of superconducting tapes (for example, REBCO CC tape) at low temperatures (for example, less than or equal to 65K). For example, the apparatus may be a force magnetometer. The apparatus may include one or more reels and pulleys used to move the superconducting tape into and out of a cryostat. The apparatus may also include a permanent magnet or electromagnet provided at a low temperature proximate to the tape. The magnet induces screening currents in the tape. The apparatus may also include an electric motor used to drive movement of the tape relative to the magnet. A tension meter may be provided to measure a tension of the tape. Alternatively, a current provided to the motor may also be measured. The apparatus may be used to measure the critical current at various positions on the superconducting tape at the low temperatures.
Florida State University Research Foundation, Incorporated. (USA)
Inventeur(s)
Frederich, James H.
Solans, Megan M.
Abrégé
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein is versatile polyene cyclization strategy that exploits conjugated β-ionyl derivatives. Photomediated disruption of the extended π-system within these chromophores unveils a contra-thermodynamic polyene that engages in a Heck-type cyclization to afford [4.4.1]-propellanes. The connectivity of overbred polycycles generated from this process is controlled by the position of the requisite C-Halide bond. Thus, compared to conventional biomimetic polyene cyclization, this approach allows for complete control of regiochemistry and facilitates incorporation of both electron-rich and electron-deficient (hetero)aryl groups. This strategy was successfully applied to the total synthesis of abietanes such as, for example, taxodione and salviasperanol, two isomeric abietane-type diterpenes that previously could not be prepared along the same synthetic pathway.
C07D 215/227 - Atomes d'oxygène liés en position 2 ou 4 un seul atome d'oxygène qui est lié en position 2
C07C 13/68 - Hydrocarbures polycycliques ou leurs dérivés hydrocarbonés acycliques à cycles condensés à plus de trois cycles condensés le système cyclique condensé ne contenant que quatre cycles à système cyclique ponté
C07C 22/08 - Composés cycliques contenant des atomes d'halogène liés à un atome de carbone acyclique ayant une insaturation dans les cycles contenant des cycles aromatiques à six chaînons contenant du fluor
C07C 25/22 - Hydrocarbures halogénés aromatiques polycycliques à cycles condensés
C07C 35/44 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle autre qu'un cycle aromatique à six chaînons polycycliques, avec au moins un groupe hydroxyle lié à un système cyclique condensé le groupe hydroxyle étant sur un système cyclique condensé à plus de trois cycles
C07C 43/215 - Éthers une liaison sur l'oxygène de la fonction éther étant sur un atome de carbone d'un cycle aromatique à six chaînons avec une insaturation autre que celle des cycles aromatiques à six chaînons
C07C 49/753 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes éther, des groupes , des groupes ou des groupes
C07C 49/755 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes éther, des groupes , des groupes ou des groupes un groupe cétone faisant partie d'un système cyclique condensé de deux ou trois cycles, un des cycles au moins étant un cycle aromatique à six chaînons
C07D 215/06 - Composés hétérocycliques contenant les systèmes cycliques de la quinoléine ou de la quinoléine hydrogénée ne comportant pas de liaison entre l'atome d'azote du cycle et un chaînon non cyclique ou ne comportant que des atomes d'hydrogène ou de carbone liés directement à l'atome d'azote du cycle avec uniquement des atomes d'hydrogène ou des radicaux ne contenant que des atomes d'hydrogène et de carbone, liés directement aux atomes de carbone du cycle comportant uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés à l'atome d'azote du cycle
C07D 307/79 - Benzo [b] furannesBenzo [b] furannes hydrogénés avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone de l'hétérocycle
39.
METHODS AND COMPOSITIONS FOR DETERMINING MICROORGANISM PRESENCE AND CONCENTRATION USING PCR PRIMERS OF VARYING AMPLIFICATION EFFICIENCIES
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventeur(s)
Singh, Prashant
Bosilevac, Joseph M.
Abrégé
Disclosed herein are methods and kits for quantifying the presence of a microorganism in a sample. Specifically, disclosed are methods for quantifying a pathogen in a sample, such as a food sample, to determine if the levels of pathogen present in the sample are within an acceptable range.
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Li, Hui
Guo, Zhehui
Abrégé
The disclosure relates to devices, systems and methods implementing a charge pump gate driver (CPGD) that offers adjustable pump voltage, enabling online and active dv/dt and di/dt control for power devices, including the wide bandgap devices, such as SiC MOSFETs and GaN HEMTs. The disclosed CPGD allows a flexible pump voltage adjustment through the pre-charging interval control. Both the turn-on and turn-off switching speed (both dv/dt and di/dt) of power devices can be online regulated rapidly within each switching cycle, without interrupting the power converter operation. The disclosed CPGD has a simple structure and eliminates the extra power supplies to reduce circuit cost and footprint.
H03K 17/06 - Modifications pour assurer un état complètement conducteur
H03K 17/0412 - Modifications pour accélérer la commutation sans réaction du circuit de sortie vers le circuit de commande par des dispositions prises dans le circuit de commande
H03K 17/687 - Commutation ou ouverture de porte électronique, c.-à-d. par d'autres moyens que la fermeture et l'ouverture de contacts caractérisée par l'utilisation de composants spécifiés par l'utilisation, comme éléments actifs, de dispositifs à semi-conducteurs les dispositifs étant des transistors à effet de champ
41.
PREDICTIVE-CONTROL BASED LOW-VOLTAGE-RIDE-THROUGH METHOD FOR A GRID-TIED INVERTER
H02M 7/539 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs, p. ex. onduleurs à impulsions à un seul commutateur avec commande automatique de la forme d'onde ou de la fréquence de sortie
H02J 3/00 - Circuits pour réseaux principaux ou de distribution, à courant alternatif
42.
LIGNIN-BASED BIODEGRADABLE POLYMERS AND METHODS OF MAKING THE SAME
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Chung, Hoyong
Abrégé
Disclosed are methods of forming lignin-based biodegradable polymers. The methods comprise the use of a coupling reagent allowing formation between lignin-based material and an additional polymer material. The formed polymers include lignin-based polycarbonates, lignin-based polyurethanes, and lignin-based polyesters.
C08L 67/00 - Compositions contenant des polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
C08L 69/00 - Compositions contenant des polycarbonatesCompositions contenant des dérivés des polycarbonates
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Chung, Hoyong
Abrégé
Disclosed are methods of forming lignin-based recyclable polymers. The methods comprise using a carbon dioxide-containing gas as a reagent to form a lignin-based polycarbonate. Also disclosed are methods for capturing carbon dioxide gas and recycling lignin-based materials.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Cooley, Lance D.
Hubicki, Christian M.
Abrégé
Example coil guns and methods of using coil guns are described herein. An example coil gun includes a first pancake module; a second pancake module, where the first pancake module and the second pancake module are each formed of a winding with an inner superconducting material layer and an outer ordinary conductor layer, where the first pancake module and the second pancake module are physically and/or inductively coupled to propagate a quench of a superconducting state of the first pancake module to the second pancake module.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Nienhaus, Lea
Abrégé
In one aspect, the disclosure a system for near infrared-to-green upconversion of light in solid-state optoelectronic devices, the system comprising a bulk semiconductor layer capable of absorbing a near-infrared first wavelength of light and an organic annihilator in contact with the bulk semiconductor, wherein the organic annihilator is capable of upconversion via triplet-triplet annihilation from triplet states in the organic annihilator to produce green light at a second wavelength. In one aspect, the bulk semiconductor can be a formamidinium-based metal halide perovskite and the organic annihilator can be a polycyclic aromatic hydrocarbon or derivative thereof. Also disclosed are devices incorporating the same and methods for upconverting near infrared light to green light.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ma, Biwu
He, Qingquan
Abrégé
Methods of passivating a surface. The methods may include providing a mixture including a liquid and a derivative of quinacridone, applying the mixture to a first surface of a film that includes a metal halide perovskite, and annealing the film for a time and a temperature effective to convert the derivative of quinacridone to quinacridone. Composite materials and electronic devices also are provided.
B05D 1/00 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces
H10K 30/10 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant des hétérojonctions entre des semi-conducteurs organiques et des semi-conducteurs inorganiques
47.
Organic Pigment Coating for Electronic Devices, Perovskite Solar Cells, and Methods
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ma, Biwu
He, Qingquan
Abrégé
Methods of passivating a surface. The methods may include providing a mixture including a liquid and a derivative of quinacridone, applying the mixture to a first surface of a film that includes a metal halide perovskite, and annealing the film for a time and a temperature effective to convert the derivative of quinacridone to quinacridone. Composite materials and electronic devices also are provided.
B05D 1/00 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces
H10K 30/10 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant des hétérojonctions entre des semi-conducteurs organiques et des semi-conducteurs inorganiques
48.
LIGNIN-BASED BIODEGRADABLE POLYMERS AND METHODS OF MAKING THE SAME
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Chung, Hoyong
Abrégé
Disclosed are methods of forming lignin-based recyclable polymers. The methods comprise using a carbon dioxide-containing gas as a reagent to form a lignin-based polycarbonate. Also disclosed are methods for capturing carbon dioxide gas and recycling lignin-based materials.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Krick, Brandon Alexander
Van Meter, Kylie
Abrégé
Systems and methods are provided for in situ observation of reservoirs, such as syringes, during the freeze thaw cycle to allow for more in depth understanding of the behavior of the system. The systems and methods may include an inert environment and/or a low concentration (e.g., on the order of parts per million (ppm)) of water, which may inhibit frost formation.
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Chung, Hoyong
Abrégé
Disclosed are methods of forming lignin-based biodegradable polymers. The methods comprise the use of a coupling reagent allowing formation between lignin-based material and an additional polymer material. The formed polymers include lignin-based polycarbonates, lignin-based polyurethanes, and lignin-based polyesters.
C08G 81/02 - Composés macromoléculaires obtenus par l'interréaction de polymères en l'absence de monomères, p. ex. polymères séquencés au moins un des polymères étant obtenu par des réactions ne faisant intervenir que des liaisons non saturées carbone-carbone
C08L 51/00 - Compositions contenant des polymères greffés dans lesquels le composant greffé est obtenu par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carboneCompositions contenant des dérivés de tels polymères
C08F 289/00 - Composés macromoléculaires obtenus par polymérisation de monomères sur des composés macromoléculaires non prévus par les groupes
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Zhang, Jinfeng
Lo, Chun-Chao
Abrégé
Described herein are systems and methods for performing literature retrieval and related machine learning model training methods. An example computer-implemented method of training a machine learning model configured for literature retrieval I includes receiving a plurality of full-text articles; extracting, from the plurality of full-text articles, a plurality of positive sentence-citation pairs, each positive sentence-citation pair comprising a respective citing sentence and at least one cited article that is associated with the respective citing sentence; creating a labeled dataset comprising the plurality of positive sentence-citation pairs; and training a machine learning model using the labeled dataset.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Eze, Vincent O.
Okoli, Okenwa
Abrégé
Organic photovoltaic materials (OPV) and devices using the same are provided, as well as methods of fabricating and using the same. An OPV material can be used as a photo-absorbing layer for mechanoluminescent (ML) light (e.g., in a flexible organic ML photodiode). The OPV material can include, for example, a blend of a donor polymer (e.g., P3HT) and a non-halogenated, non-fullerene acceptor (e.g., Y6).
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
LABORATORY OF COORDINATION CHEMISTRY OF THE FRENCH NATIONAL CENTRE FOR SCIENTIFIC RESEARCH (France)
Inventeur(s)
Mattoussi, Hedi
Du, Liang
Wang, Wentao
Amiens, Catherine
Grant, Samuel
Abrégé
Contrast agents, compositions including contrast agents, methods of forming contrast agents, and methods of imaging. Contrast agents may have a desirable solubility in liquids, such as aqueous liquids. Methods of forming contrast agents may include contacting a polymer that includes anhydride functional groups with one or more compounds. Methods of imaging may include administering to patients a contrast agent or composition including a contrast agent.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Schlenoff, Joseph
Lteif, Sandrine
Abrégé
Described herein stabilized polysiloxane particles and methods for making and using the same. In one aspect, the composite includes (a) a polysiloxane comprising one or more positively charged groups and a negatively charged polyelectrolyte polymer or (b) a polysiloxane comprising one or more negatively charged groups and a positively charged polyelectrolyte polymer. Additionally, components such as, for example, inorganic drying agent, a filler, a reinforcing agent, magnetic particles, a wet/dry indicator, a pharmaceutical agent, a catalyst, or any combination thereof. The composites are effective in encapsulating hydrophobic materials that can subsequently be dispersed in aqueous medium.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Zeng, Changchun
Liang, Zhiyong
Li, Yan
Luo, Sida
Liu, Tao
Abrégé
The present invention includes scalable and cost-effective auxetic foam sensors (AFS) created through conformably coating a thin conductive nanomaterial-sensing layer on a porous substrate having a negative Poisson's ratio. In general, the auxetic foam sensors possess multimodal sensing capability, such as large deformation sensing, small pressure sensing, shear/torsion sensing and vibration sensing and excellent robustness in humidity environment.
G01L 1/18 - Mesure des forces ou des contraintes, en général en utilisant des propriétés des matériaux piézo-résistants, c.-à-d. des matériaux dont la résistance ohmique varie suivant les modifications de la grandeur ou de la direction de la force appliquée au matériau
G01L 1/22 - Mesure des forces ou des contraintes, en général en mesurant les variations de la résistance ohmique des matériaux solides ou des fluides conducteurs de l'électricitéMesure des forces ou des contraintes, en général en faisant usage des cellules électrocinétiques, c.-à-d. des cellules contenant un liquide, dans lesquelles un potentiel électrique est produit ou modifié par l'application d'une contrainte en utilisant des jauges de contrainte à résistance
G01R 29/22 - Mesure de propriétés piézo-électriques
B32B 37/24 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par les propriétés des couches avec au moins une couche qui ne présente pas de cohésion avant la stratification, p. ex. constituée de matériau granulaire projeté sur un substrat
B29C 44/34 - Éléments constitutifs, détails ou accessoiresOpérations auxiliaires
B82Y 40/00 - Fabrication ou traitement des nanostructures
G01L 1/26 - Mesures auxiliaires prises, ou dispositifs utilisés en liaison avec le mesurage des forces, p. ex. pour empêcher l'influence des composantes transversales de la force, pour empêcher la surcharge
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ma, Biwu
Shonde, Tunde B.
Chaaban, Maya
Abrégé
Organic metal halide hybrid-based scintillation materials are provided, as well as methods of fabricating and using the same. The scintillation materials can be zero-dimensional (0D) organic metal halide hybrid-based scintillation materials, such as 4-(4-(diphenylamino) phenyl)-1-(Propyl)-pyrindin-lium zinc bromide ((TPA-P)2ZnBr4), in which at least one metal halide anion (e.g., ZnBr42−) act(s) as an X-ray sensitizer and at least one aggregate induced emission (AIE) organic cation (e.g., TPA-P+) act(s) as a light emitter.
C09K 11/54 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du zinc ou du cadmium
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Singh, Prashant
Abrégé
Determining whether a particular sample is what it is labeled or sold as is an important concept, particularly to those who buy or sell food products. Particularly for end users, a fast, efficient, accurate way of determining whether a sample is being accurately marketed and sold is necessary. This invention allows a user to rapidly determine if a product is from a certain species or not, based on genetic markers for that product.
C12Q 1/6888 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes
59.
CLASSICAL CONDITIONING OF NEUROMODULATION WITH SYNCHRONIZED MUSICAL STIMULATION
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Johnson, Kevin
Kozel, Frank Andrew
Standley, Jayne
Abrégé
A device may include a transcranial magnetic stimulation (TMS) device configured to generate a localized magnetic field waveform at a brain region. A device may include an acoustic controller configured to generate an audio waveform having at least one of rhythm, harmonic element, or melodic element synchronized to the localized magnetic field waveform. In various implementations, the brain region is a motor cortex of a patient. The device can evoke or produce neurostimulation effects through acoustic stimulation (e.g., music) through classical (or Pavlovian) conditioning paired in combination with synchronized transcranial magnetic stimulation output. The device can be used to extend the effects of neuromodulation, thus reducing the burden of in-patient visits (for procedural neurostimulation), reducing battery life demand of implanted devices, or simply improving the patient experience with achieving benefits (i.e., by listening to music versus unnatural sensory sensations with neurostimulation).
A61B 5/395 - Détails de la stimulation, p. ex. stimulation d’un nerf pour provoquer une réponse EMG
A61N 2/02 - Magnétothérapie utilisant des champs magnétiques produits par des bobines, y compris par des boucles à spire unique ou par des électro-aimants
G10H 1/00 - Éléments d'instruments de musique électrophoniques
60.
fNIRS for Dosing Transcranial Magnetic Brain Stimulation
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Kozel, Frank Andrew
Johnson, Kevin
Abrégé
A system may measure, via a functional Near-Infrared Spectroscopy (fNIRS) device, a first set of measurements of a prefrontal cortex region of a patient. The system may perform, via a transcranial magnetic stimulation (TMS) device, TMS treatment to the prefrontal cortex region for therapeutic effect. The fNIRS device may measure a second set of measurements of the prefrontal cortex region. The system includes a processor to determine an applied dosing of the TMS treatment based on the first set of measurements and/or the second set of measurements. The system may output control feedback to the TMS device or visualization to a display to adjust one or more parameters or localization of the TMS treatment based on the applied dosing. The system personalizes the treatment dosing of TMS more accurately over the prefrontal cortex by calibrating the dose to the prefrontal cortex based on measurements from the fNIRS device.
A61N 2/02 - Magnétothérapie utilisant des champs magnétiques produits par des bobines, y compris par des boucles à spire unique ou par des électro-aimants
61.
Small Molecule Inhibitors of SARS-CoV-2 Infections
The USA, as represented by The Secretary, Dept. of Health and Human Services (USA)
The Florida State University Research Foundation (USA)
Inventeur(s)
Huang, Wenwei
Shamim, Khalida
Tang, Hengli
Abrégé
The present disclosure relates generally to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), commonly referred to as coronavirus disease 2019 (COVID-19). The present disclosure relates more particularly to small molecule inhibitors of SARS-CoV-2 of Formula (II) and prodrug derivatives thereof of Formula (I), and methods of treating COVID-19 therewith.
The present disclosure relates generally to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), commonly referred to as coronavirus disease 2019 (COVID-19). The present disclosure relates more particularly to small molecule inhibitors of SARS-CoV-2 of Formula (II) and prodrug derivatives thereof of Formula (I), and methods of treating COVID-19 therewith.
C07C 235/84 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des atomes d'oxygène ayant des atomes de carbone de groupes carboxamide et des atomes d'oxygène, liés par des liaisons doubles, liés au même squelette carboné avec l'atome de carbone d'au moins un des groupes carboxamide lié à un atome de carbone d'un cycle aromatique à six chaînons
C07D 211/46 - Atomes d'oxygène liés en position 4 comportant un atome d'hydrogène comme second substituant en position 4
C07D 209/26 - Radicaux substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile avec un radical acyle lié à l'atome d'azote du cycle
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Li, Yan
Ma, Teng
Abrégé
Improved hybrid neurovascular spheroids and methods for making the same are provided. In some embodiments of a method for making a hybrid neurovascular spheroid, the method includes i) propagating cortical cells to form a cortical spheroid; ii) propagating endothelial cells to form an endothelial spheroid; iii) propagating mesenchymal stem cells to form a mesenchymal cell culture; and iv) combining the cortical spheroid, endothelial spheroid, and mesenchymal spheroid under conditions to form the hybrid neurovascular spheroid.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Lipo, Thomas A.
Imakiire, Akihiro
Abrégé
An induction machine with localized voltage unbalance compensation is disclosed. The use of an induction machine with a voltage unbalance correction compensator (VUC) may be used to maintain proper working conditions of the machine during intervals of voltage unbalance.
H02P 29/024 - Détection d’un défaut, p. ex. court circuit, rotor bloqué, circuit ouvert ou perte de charge
H02P 1/26 - Dispositions de démarrage de moteurs électriques ou de convertisseurs dynamo-électriques pour faire démarrer des machines dynamo- électriques ou des convertisseurs dynamo-électriques pour faire démarrer individuellement un moteur à induction polyphasé
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Holmes, Eric
Ostrander, Gary
Abrégé
The present invention concerns compositions comprising at least one niclosamide compound, such as niclosamide or a pharmaceutically acceptable salt thereof, and at least one permeability enhancer, such as glycerol or dimethylpalmityl-ammonio propanesulfonate (PPS), and their use of such compositions as niclosamide agents. Advantageously, the niclosamide compound is capable of being transported across a Caco-2 cell membrane by at least 150% relative to the amount capable of being transported across the Caco-2 cell membrane in the absence of the permeability enhancer. Compositions, including oral dosage forms, and methods for delivering niclosamide compounds, such as for treatment or prevention of human coronavirus infections, are also provided.
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 9/28 - DragéesPilules ou comprimés avec revêtements
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61K 47/20 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant du soufre, p. ex. sulfoxyde de diméthyle [DMSO], docusate, laurylsulfate de sodium ou acides aminosulfoniques
A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ma, Biwu
Zhou, Chenkun
Lin, Haoran
Tian, Yu
Abrégé
Bulk assemblies are provided, which may have desirable photoluminescence quantum efficiencies. The bulk assemblies may include two or more metal halides, and a wide band gap organic network. The wide band gap organic network may include organic cations. The metal halides may be disposed in the wide band gap organic network. Light emitting composite materials also are provided.
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
C09K 11/66 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du germanium, de l'étain ou du plomb
C09K 11/74 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant de l'arsenic, de l'antimoine ou du bismuth
C09K 11/77 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant des métaux des terres rares
H05B 33/14 - Sources lumineuses avec des éléments radiants ayant essentiellement deux dimensions caractérisées par la composition chimique ou physique ou la disposition du matériau électroluminescent
H05B 33/20 - Sources lumineuses avec des éléments radiants ayant essentiellement deux dimensions caractérisées par la composition chimique ou physique ou la disposition du matériau dans lequel le matériau électroluminescent est enrobé
66.
CYTOSOLIC MICROPARTICLES, PHAGOCYTIC CELLS COMPRISING THE SAME, AND METHODS FOR TREATING DISEASE COMPRISING THE SAME
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Cheng, Wenhao
Guan, Jingjiao
Abrégé
In one aspect, the disclosure relates to cytosolic microparticles comprising a polymeric material such as, for example, poly(N-isopropylacrylamide) (PNIPAM), and containing nanoparticles, and methods for producing the same. The disclosure further relates to phagocytic cells such as macrophages containing the cytosolic microparticles, wherein the microparticles are not subject to the harsh environment of the phagosome. Also disclosed are compositions containing the phagocytic cells and methods for treating diseases in a subject, including various cancers, wherein the methods include administering the phagocytic cells or disclosed compositions to a subject.
A61K 31/715 - Polysaccharides, c.-à-d. ayant plus de cinq radicaux saccharide liés les uns aux autres par des liaisons glycosidiquesLeurs dérivés, p. ex. éthers, esters
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Smith, Joel Michael
Abrégé
Methods of preparation of lysergic acid and derivatives thereof. Methods of using lysergic acid and derivatives thereof, such as methods of treating neurodegenerative disorders. Derivatives of lysergic acid and pharmaceutically acceptable salts thereof.
C07D 401/06 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 457/04 - Composés hétérocycliques contenant des systèmes cycliques indolo [4, 3-f, g] quinoléine, p. ex. dérivés d'ergoline, de formule p. ex. acide lysergique avec des atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement en position 8
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61K 31/48 - Dérivés de l'ergoline, p. ex. acide lysergique, ergotamine
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Smith, Joel Michael
Abrégé
Methods of preparation of lysergic acid and derivatives thereof. Methods of using lysergic acid and derivatives thereof, such as methods of treating neurodegenerative disorders. Derivatives of lysergic acid and pharmaceutically acceptable salts thereof.
C07D 457/02 - Composés hétérocycliques contenant des systèmes cycliques indolo [4, 3-f, g] quinoléine, p. ex. dérivés d'ergoline, de formule p. ex. acide lysergique avec des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés en position 8
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Dubroca, Thierry
Trociewitz, Bianca
Mckay, Johannes
Mentink-Vigier, Frederic
Abrégé
Apparatuses and methods for removing caps, such as NMR rotor caps. The apparatuses and methods may permit caps to be removed in a manner that minimizes damage to equipment and instruments. Microwave waveguides that may include an elongated waveguide, a spline horn, and a slotted waveguide. Analytical instruments that include the waveguides.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Dubroca, Thierry
Trociewitz, Bianca
Mckay, Johannes
Mentink-Vigier, Frederic
Abrégé
Apparatuses and methods for removing caps, such as NMR rotor caps. The apparatuses and methods may permit caps to be removed in a manner that minimizes damage to equipment and instruments. Microwave waveguides that may include an elongated waveguide, a spline horn, and a slotted waveguide. Analytical instruments that include the waveguides.
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Kim, Ryounghee
Cho, Jeongju
Miara, Lincoln
Patel, Sawankumar
Wang, Yan
Hu, Yan-Yan
Gwon, Hyeokjo
Kim, Sewon
Kim, Jusik
Jung, Sungkyun
Abrégé
0≤x≤2, 0≤y<1, and 0≤z≤2, except that cases i) x and y and z are simultaneously 0, ii) M is Hf, X is F, x is 1, y is 0, and z is 1, iii) M is Hf, X is Cl, x is 2, y is 0, and z is 2, and iv) M is Hf, X is F, x is 2, y is 0, and z is 2.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Khanam, Jobeda Jamal
Foo, Simon Y.
Abrégé
Photovoltaic devices, and methods of fabricating photovoltaic devices. The photovoltaic devices may include a first electrode, at least one quantum dot layer, at least one semiconductor layer, and a second electrode. The first electrode may include a layer including Cr and one or more silver contacts.
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
H01L 31/032 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés non couverts par les groupes
73.
Using Hairpin Formation To Identify DNA and RNA Sequences Having A Target Nucleic Acid Sequence
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Lemmon, Alan R.
Abrégé
DNA or RNA including a target nucleotide sequence are amplified by placing a probe nucleotide sequence on the DNA or RNA. The probe nucleotide sequence is complementary to the target nucleotide sequence. The interaction between the probe nucleotide sequence and target nucleotide sequence causes the single-stranded DNA to form a hairpin. The hairpinned single-stranded DNA are selected for amplification.
The Florida State University Research Foundation, Inc. (USA)
Laboratory of Coordination Chemistry of the French National Centre for Scientific Research (France)
Inventeur(s)
Mattoussi, Hedi
Du, Liang
Wang, Wentao
Amiens, Catherine
Grant, Samuel
Abrégé
Contrast agents, compositions including contrast agents, methods of forming contrast agents, and methods of imaging. Contrast agents may have a desirable solubility in liquids, such as aqueous liquids. Methods of forming contrast agents may include contacting a polymer that includes anhydride functional groups with one or more compounds. Methods of imaging may include administering to patients a contrast agent or composition including a contrast agent.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Khanam, Jobeda Jamal
Foo, Simon Y.
Abrégé
Photovoltaic devices, and methods of fabricating photovoltaic devices. The photovoltaic devices may include a first electrode, at least one quantum dot layer, at least one semiconductor layer, and a second electrode. The first electrode may include a layer including Cr and one or more silver contacts.
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
H01L 31/032 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés non couverts par les groupes
76.
MOLD AND TESTING FIXTURE FOR FIBER INTERFACE STRENGTH TEST
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Sweat, Rebekah
Horne, Gerald
Hao, Ayou
De Leon, Ana
Tank, Mehul
Abrégé
Various implementations include a mold for forming composite samples for a pullout test. The mold includes a body having a first surface and a second surface spaced apart from the first surface. The first surface defines one or more slots and one or more channels. Each of the one or more channels has a longitudinal axis. At least one of the one or more channels intersects one of the one or more slots. Various other implementations include a method of forming a composite sample for a pullout test. The method includes providing a mold as described above; disposing a resin within one of the slots; disposing a fiber within at least one of the channels intersecting the one of the slots such that a portion of the fiber is disposed within the one of the slots; and causing the resin to cure.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Gunjan, Akash
Son, Yuna
Abrégé
The invention concerns molecular biomarkers useful for screening individuals for steroid resistance and steroid sensitivity in the selection of treatments for keloids and other conditions. Aspects of the invention include a method for determining whether or not an individual will respond beneficially to a steroid therapy; a method for selecting a therapy for an individual having a condition, using the screening method; a method for treating a condition of an individual, using the screening method; and a detection device useful for detecting expression levels of the biomarkers.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Lenhert, Steven
Shiel, Emily
Zhou, Huanhuan
Abrégé
The present disclosure provides for a method of detecting the displacement of a specific analyte, including providing an indicator in an organic phase to form a first composition; providing an aqueous phase with a test analyte to form a second composition; adding at least one organic solute to the organic phase; putting the first composition and second composition in contact with each other, thereby forming a lamellar phase and an interface between the first composition and second composition; and detecting the presence of the indicator in the organic phase, wherein the presence of the indicator in the organic phase indicates the presence of the specific analyte. The present disclosure also provides for a method of developing a high throughput assay for contemporaneous detection of multiple analytes. Further, the present disclosure provides for a biosensor for detection of a specific analyte.
G01N 33/92 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des lipides, p. ex. le cholestérol
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
79.
USING FLUORESCENT COLLAGEN .alpha. 1(I) AND .alpha. 2(I) mRNAs TO SCREEN DRUG CANDIDATES
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Stefanovic, Branko
Abrégé
Fluorescent collagen a1(I) and a2(I) mRNA compounds can be used to detect whether a test compound affects the binding of collagen a1(I) and/or a2(I) mRNAs to LARP6 protein. Fluorescent collagen a1(I) and a2(I) mRNA compounds include collagen a1(I) and a2(I) mRNA sequences that have been tagged with a fluorophore and have LARP6 binding affinity.
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
C12Q 1/6876 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes
80.
ABIETANES AND METHODS OF MAKING AND USING THE SAME
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INCORPORATED (USA)
Inventeur(s)
Frederich, James, H.
Solans, Megan, M.
Abrégé
bb-ionyl derivatives. Photomediated disruption of the extended p-system within these chromophores unveils a contra-thermodynamic polyene that engages in a Heck-type cyclization to afford [4.4.1]-propellanes. The connectivity of overbred polycycles generated from this process is controlled by the position of the requisite C–Halide bond. Thus, compared to conventional biomimetic polyene cyclization, this approach allows for complete control of regiochemistry and facilitates incorporation of both electron-rich and electron-deficient (hetero)aryl groups. This strategy was successfully applied to the total synthesis of abietanes such as, for example, taxodione and salviasperanol, two isomeric abietane-type diterpenes that previously could not be prepared along the same synthetic pathway.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Hanson, Kenneth
Oates, William
Beery, Drake
Stanisauskis, Eugenia
Abrégé
Photopolymers, monomers, compositions including photopolymers and a dopant, and methods, including methods for eliciting a photomechanical response. The dopant may be a triplet sensitizing dopant. The exposing of compositions to the one or more wavelengths of electromagnetic radiation may elicit a photomechanical response via a triplet excited state mechanism.
H10K 30/00 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire
C08G 73/06 - Polycondensats possédant des hétérocycles contenant de l'azote dans la chaîne principale de la macromoléculePolyhydrazidesPolyamide-acides ou précurseurs similaires de polyimides
82.
SYMMETRIC QUENCH PROTECTION OF RESISTIVE INSULATION COILS
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Markiewicz, William Denis
Bird, Mark D.
Dixon, Iain R.
Marshall, William Scott
Painter, Thomas A.
Xu, Peng
Abrégé
A magnet includes a stack of a plurality of superconducting pancake wound coils having a stacking axis normal to a winding direction of the coils. The stack has axial ends and has a stack midplane relative to the stacking axis. A quench detector is provided for detecting a quench in the stack of superconducting pancake wound coils. A plurality of resistance quench heaters (RQH) are distributed symmetrically along the axis with respect to the stack midplane. Control circuitry is provided for controlling the operation of the RQH upon the detection of a quench by the quench detector. A method of quenching a magnet is also disclosed.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ordonez, Camilo
Hubicki, Christian
Abrégé
Multi-media parcel delivery systems and associated methods are provided herein including systems capable of delivering a parcel through air and one or more bodies of water. In certain embodiments, an aerial vehicle is configured to couple to the parcel using a cable. A control system is used to control operating parameters including velocity, altitude, and pose of the aerial vehicle, and a length and orientation of the cable extending between the aerial vehicle and the parcel.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Hanson, Kenneth
Schoenzart, Thomas Edward
Salpage, Sahan
Abrégé
Provided herein are photochemical separations. The methods herein can include exposing a first metal complex and a second metal complex to light to facilitate an irreversible chemical reaction to form a modified first metal complex. The modified first metal complex then may be separated from the second metal complex. Compositions also are provided.
C07B 63/02 - PurificationSéparation spécialement adaptée aux fins d'isolement des composés organiquesStabilisationEmploi d'additifs par un traitement donnant lieu à une modification chimique
C07F 5/00 - Composés contenant des éléments des groupes 3 ou 13 du tableau périodique
C07F 15/00 - Composés contenant des éléments des groupes 8, 9, 10 ou 18 du tableau périodique
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Moon, Jinyeong
Yi, Lifang
Abrégé
A non-intrusive, in-situ power method for measuring the loss associated with magnetic components (for example, an inductor) of a power converter is provided. The method involves first capturing a first set of voltage and current waveforms from the power converter. An additional capacitor is then connected to the power converter and a second set of voltage and current waveforms are captured. Based on the first set of waveforms and the second set of waveforms, a timing skew between the current and voltage waveforms captured from the power converter may be determined. This timing skew may then be used to determine the loss of the inductor. The loss may be used to design an optimized power converter.
The Florida State University Research Foundation, Inc. (USA)
The United States of America, as presented by the Secretary of Agriculture (USA)
Inventeur(s)
Singh, Prashant
Bosilevac, Joseph M.
Abrégé
Disclosed herein are methods and kits for quantifying the presence of a microorganism in a sample. Specifically, disclosed are methods for quantifying a pathogen in a sample, such as a food sample, to determine if the levels of pathogen present in the sample are within an acceptable range.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Tang, Youneng
Hoque, Sarajeen Saima
Xiong, Yi
Abrégé
Bioreactors and associated methods are provided herein including bioreactors capable of treating water contaminated with 1,4-dioxane. In certain embodiments, a bioreactor is disclosed and may include an adsorbent layer with a biofilm capable of metabolizing 1,4-dioxane and a screen disposed downstream of the adsorbent layer configured to retain detached biofilm.
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Blaber, Michael
Longo, Liam M.
Abrégé
A synthetic foldable protein has a tertiary structure emulating the tertiary structure of a reference foldable protein. The reference foldable protein has a folding nucleus peptide sequence associated with folding the reference foldable protein. The synthetic foldable protein also has a peptide sequence including the folding nucleus peptide sequence and at least one repeat thereof.
Arizona Board of Regents on Behalf of Arizona State University (USA)
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Tang, Youneng
Rittmann, Bruce
Zhou, Chen
Luo, Yihao
Krajmalnik-Brown, Rosa
Abrégé
Disclosed herein are systems and methods for removing trichloroethane (TCA), trichloroethene (TCE), and 1,4-dioxane (1,4-D) from contaminated liquids. The system and methods rely on catalyst reduction of TCA and TCE, where the reduced products are then degraded by microorganisms The system comprises a first reactor comprising a catalyst film of precious metal nanoparticles deposited on a first nonporous membrane and a second reactor comprising a biofilm of microorganisms that are capable of degrading ethane and 1,4-D deposited on a second nonporous membrane. The first reactor further comprises a hydrogen gas source, wherein the hydrogen gas source delivers hydrogen to the gas-phase side of the first nonporous membrane, and the catalyst film is deposited on the liquid-phase side. The second reactor further comprises an oxygen gas source, wherein the oxygen gas source delivers oxygen to the gas-phase side of the second non-porous membrane, and the biofilm is deposited on the liquid-phase side.
B01J 35/00 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général
B01J 35/23 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général caractérisés par leur état non solide sous forme colloïdale
B01J 35/30 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général caractérisés par leurs propriétés physiques
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Yu, Zhibin
Sweat, Rebekah
Abrégé
Composite materials that include a plurality of nanofibers and a ceramic. Methods of forming composite materials, which may include removing a liquid from a dispersion that includes a plurality of nanofibers, a pre-ceramic precursor, and a liquid to form an intermediate material, and annealing the intermediate material. A pre-ceramic precursor may be added before or after removal of a liquid. An article having a surface on which a composite material is disposed.
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Ma, Biwu
Tian, Yu
Abrégé
A new type of charge transport layer based on organometal halide perovskite for highly efficient organic light emitting diodes (OLEDs) is demonstrated. By solution processing of halide perovskite precursors, smooth essentially pure perovskite thin films may be prepared with high transparency and conductivity. Solution processed multilayer OLED with this perovskite-based hole transport layer outperforms a device with a PEDOT:PSS layer.
H10K 30/10 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant des hétérojonctions entre des semi-conducteurs organiques et des semi-conducteurs inorganiques
H10K 50/11 - OLED ou diodes électroluminescentes polymères [PLED] caractérisées par les couches électroluminescentes [EL]
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Steurer, Michael
Montanari, Gian Carlo
Diendorfer, Christoph
Yang, Qichen
Abrégé
Systems and methods are provided for producing optimized electronic components. Particularly, the systems and methods may involve the use of a "three-legged approach" for determining design parameters for electrical components (and/or insulation of the electrical components) such that the electrical component is not subject to partial discharges (PDs) at a maximum operating voltage of the electrical component. The approach may involve extracting maximum bulk (e.g., orthogonal) and surface (e.g., tangential) electrical stress (e.g., electrical field) information at operating temperatures, comparing the values of these electric fields with electric field values that are likely to cause the inception of one or more PDs in the electrical component (which may be determined through modeling), and linking these results with PD measurements (such as the surface partial discharge inception voltage, SPDIV).
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Chen, Gang
Abrégé
The present disclosure provides for a method of making a plant growth medium comprising isolating cellulose nanocrystals from a feedstock, and adding the cellulose nanocrystals to the plant growth medium. Further provided herein is a plant starter plug comprising the plant growth medium. Also provided herein is a plant growth medium comprising germination material and cellulose nanocrystals, and a plant starter plug comprising thereof. The present disclosure further provides for a method of isolating CNCs from waste.
A01G 24/22 - Substrats de cultureMilieux de cultureAppareils ou méthodes à cet effet basés sur ou contenant de la matière organique naturelle contenant de la matière végétale
B82Y 5/00 - Nanobiotechnologie ou nanomédecine, p. ex. génie protéique ou administration de médicaments
C12N 9/42 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2) agissant sur les liaisons bêta-glucosidiques-1, 4, p. ex. cellulase
94.
Transcranial Stimulation to Treat DMN Dysfunction in Normal and Abnormal Aging
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Li, Wen
Clancy, Kevin
Abrégé
Methods are provided for treating disorders associated with default mode network (DMN) dysfunction in a patient, where the methods include administering alpha-frequency transcranial alternating current stimulation (α-tACS) to the brain of the patient via at least one electrode, and where the α-tACS is effective to regulate DMN dysfunction and treat disorders associated therewith. Diseases and disorders associated with DMN dysfunction include normal or abnormal aging, cognitive impairment, or neuropsychiatric disorders such as Alzheimer's disease, schizophrenia, autism, or posttraumatic stress disorder (PTSD).
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Gao, Hanwei
Gong, Jue
Jones, Brendon Tyler
Adnani, Moein
Abrégé
Methods of encapsulating perovskites, such as metal halide perovskites, that may include depositing a nitride or an oxide on a film that includes a perovskite. Composite materials that include a perovskite layer and a layer of a nitride or an oxide. Devices, such as electronic devices, that include composite materials.
Samsung Electronics Co., Ltd. (République de Corée)
The Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Wang, Yan
Miara, Lincoln
Hu, Yan-Yan
Feng, Xuyong
Abrégé
A compound of Formula 1
A compound of Formula 1
Li1+(4−a)αHf2−αMaα(PO4−δ)3 (1)
A compound of Formula 1
Li1+(4−a)αHf2−αMaα(PO4−δ)3 (1)
is disclosed, wherein M is at least one cationic element having a valence of a, wherein 0<α≤⅔, 1≤a≤4, and 0≤δ≤0.1. Also described are an electrolyte composition, a separator, a protected positive electrode, a protected negative electrode, and a lithium battery, each including the compound of Formula 1.
H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p. ex. LiTi2O4 ou LiTi2OxFy
H01M 50/451 - Séparateurs, membranes ou diaphragmes caractérisés par le matériau ayant une structure en couches comprenant des couches de matériau organique uniquement et des couches comprenant un matériau inorganique
H01M 50/454 - Séparateurs, membranes ou diaphragmes caractérisés par le matériau ayant une structure en couches comprenant une couche non fibreuse et une couche fibreuse superposées l’une sur l’autre
97.
TRANSCRANIAL STIMULATION TO TREAT DMN DYSFUNCTION IN NORMAL AND ABNORMAL AGING
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Li, Wen
Clancy, Kevin
Abrégé
Methods are provided for treating disorders associated with default mode network (DMN) dysfunction in a patient, where the methods include administering alpha-frequency transcranial alternating current stimulation (α-tACS) to the brain of the patient via at least one electrode, and where the α-tACS is effective to regulate DMN dysfunction and treat disorders associated therewith. Diseases and disorders associated with DMN dysfunction include normal or abnormal aging, cognitive impairment, or neuropsychiatric disorders such as Alzheimer's disease, schizophrenia, autism, or posttraumatic stress disorder (PTSD).
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
98.
SYSTEMS AND METHODS FOR RECOVERING COLLIDED PACKETS IN A WIRELESS NETWORK AND BLOCK-BASED ERROR CORRECTION
Florida State University Research Foundation, Inc. (USA)
Inventeur(s)
Zhang, Zhenghao
Abrégé
Provided are methods and apparatus for recovering collided packets in a wireless network, as well as for implementing block-based error correction techniques. In an example, provided is a method to recover collided packets by (A) assigning a peak of a collided packet to a respective packet by calculating a matching cost, per collided packet, from an amplitude of the peak and a time when the peak occurred, where the matching cost is determined from a combination of per-collided packet parameters including (i) respective estimated symbol boundaries of the collided packets, (ii) respective estimated Carrier Frequency Offsets of the collided packets, and (iii) a peak amplitude history of prior packets received from wireless network nodes, and (B) assigning, based on a respective packet in the collided packets having the parameters producing a lowest matching cost among the calculated matching costs, the peak to the respective packet.
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
THE BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (USA)
Inventeur(s)
Moon, Jinyeong
Lee, Woongkul
Alvi, Muhammad
Abrégé
A dual multi-level inverter topology with reduced switch count and small DC-link capacitor is provided. The inverter topology provides multi-level inverter operation without requiring a neutral point connection that is commonly present in a stacked capacitor topology (for example, a topology including two capacitors).
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Lu, Jun
Dixon, Iain R.
Bird, Mark D.
Deterding, Justin
Bai, Hongyu
Marks, Emsley L.
Markiewicz, William Denis
Abrégé
Coils for superconducting magnets and methods of making coils for superconducting magnets and controlling the turn-to-turn contact resistance of coils. The coils include a REBCO superconducting tape coated with a layer of tin-lead solder, co-wound with an oxidized stainless steel tape. The inclusion of tin-lead solder on the REBCO tape and a layer of oxidation on the stainless steel tape advantageously allow for tuning of the turn-to-turn contact resistance of the coil, and advantageously mitigates the effect of repeated pressure cycling on the turn-to-turn contact resistance.
H01F 6/06 - Bobines, p. ex. dispositions pour l'enroulement, l'isolation, les enveloppes ou les bornes des bobines
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateursAppareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
G01R 33/3815 - Systèmes pour produire, homogénéiser ou stabiliser le champ magnétique directeur ou le champ magnétique à gradient utilisant des électro-aimants avec des bobines supraconductrices, p. ex. leurs alimentations
H01B 12/06 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par leurs formes à couches ou fils déposés sur des supports ou des noyaux