An aspartic acid copper complex, a use thereof, and a feed composition containing said aspartic acid copper complex. The chemical structure of the aspartic acid copper complex is [(Cu(II))(Asp)(H2O)m]·(H2O)n, wherein Asp is L-Asp or DL-Asp, m is any integer from 0 to 10, and n is any value from 0 to 10. The present aspartic acid copper complex is applied to animal breeding. Calculated using the copper element, a physiological requirement usage amount may promote the growth of livestock and poultry at all stages of the growth cycle, and during high dose use, and the growth performance of the animals is normal under high-dose use, thereby overcoming problems such as excessive use of high-dose inorganic copper in the breeding industry being harmful for animals.
A23K 20/20 - Substances inorganiques, p. ex. oligo-éléments
A23K 50/30 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les porcs
A23K 50/60 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux sevrés
A23K 50/75 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les oiseaux pour la volaille
A23K 50/80 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux aquatiques, p. ex. pour les poissons, les crustacés ou les mollusques
2.
USE OF CYCLOHEXANETRIONE DERIVATIVE IN PREPARATION OF DRUG FOR ANIMALS
The present invention relates to the technical field of drugs, in particular to the use of a cyclohexanetrione derivative in the preparation of a drug for animals. At least one of the cyclohexanetrione derivative or a tautomer, solvate or pharmaceutically acceptable salt thereof provided by the present invention can be used for preparing a drug for animals, wherein the drug for animals is a drug for treating bacterial infectious diseases in animals. The cyclohexanetrione derivative of the present invention has a significant inhibitory effect on pathogenic bacteria in animals, and has a significant therapeutic effect on bacterial infectious diseases in animals.
Disclosed in the present invention is a use of a furan formic acid compound in preparing an animal feed additive for improving animal production performance. The furan formic acid compound is as shown in formula (I), wherein R1, R2, and R3 are independently H or-COOH. The furan formic acid compound or a feed acceptable salt thereof provided in the present invention has an improved effect on the production performance of domestic animals, poultry and aquaculture animals in animal breeding tests.
A23K 20/121 - Composés hétérocycliques contenant de l’oxygène ou du soufre comme hétéroatome
A61K 31/341 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à cinq chaînons avec un oxygène comme seul hétéro-atome d'un cycle, p. ex. isosorbide non condensés avec un autre cycle, p. ex. ranitidine, furosémide, bufétolol, muscarine
An aspartic acid copper complex, a use thereof, and a feed composition containing said aspartic acid copper complex. The chemical structure of the aspartic acid copper complex is [(Cu(II))(Asp)(H 2O) m]·(H 2O) n, wherein Asp is L-Asp or DL-Asp, m is any integer from 0 to 10, and n is any value from 0 to 10. The present aspartic acid copper complex is applied to animal breeding. Calculating using the copper element, a physiological requirement usage amount may promote the growth of livestock and poultry at all stages of the growth cycle, and during high dose use, and the growth performance of the animals is normal under high-dose use, thereby overcoming problems such as excessive use of high-dose inorganic copper in the breeding industry being harmful for animals.
21120231456562566 aryl) group. The diaminoguanidine derivative is a non-toxic and safe compound for animals, and is markedly effective in the treatment of infectious diseases in the reproductive system, skin, etc., of farmed animals.
C07C 281/18 - Composés contenant l'un des groupes p. ex. aminoguanidine l'autre atome d'azote étant lié de plus par une liaison double à un atome de carbone, p. ex. guanylhydrazones
6.
FEED COMPOSITION COMPRISING HEXAHYDRO-β-ACID COMPONENT COMPOUNDS AND APPLICATION THEREOF
A feed composition comprising hexahydro-β-acid component compounds shown in formula I, i.e. hexahydrocolupulone and/or hexahydroadlupulone, applications of the feed composition and the hexahydro-β-acid component compounds, and a method for using the feed composition to improve animal production performance.
C07C 49/713 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes hydroxyle un groupe cétone faisant partie d'un cycle à six chaînons
7.
Conjugate acid salt of N,N-dimethylglycine with organic acid, and composition and use thereof
18 linear fatty acid or an aromatic acid. The conjugate salt of N,N-dimethylglycine with metal and organic acid is a conjugate acid salt formed by introducing another organic acid with a hydrophobic group into the salt of N,N-dimethylglycine and a metal ion, so as to modify the hygroscopicity of N,N-dimethylglycine by decreasing the affinity of the salt toward water molecules in the air, or decreasing the affinity or attraction of molecular aggregates formed through crystalline behavior of the salt toward water molecules in the air.
A61K 31/197 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino les groupes amino et carboxyle étant liés à la même chaîne carbone acyclique, p. ex. acide gamma-aminobutyrique [GABA], bêta-alanine, acide epsilon-aminocaproïque ou acide pantothénique
A23K 20/24 - Composés de métaux alcalino-terreux, p. ex. de magnesium
A23K 20/20 - Substances inorganiques, p. ex. oligo-éléments
A23K 50/30 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les porcs
A23K 50/75 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les oiseaux pour la volaille
A23K 50/80 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux aquatiques, p. ex. pour les poissons, les crustacés ou les mollusques
A23K 20/105 - Composés aliphatiques ou alicycliques
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 33/06 - Aluminium, calcium ou magnésiumLeurs composés
A use of a substituted benzoguanidine derivative as a polymyxin antibiotic synergist, particularly as a synergist and a drug resistance reversal agent of the polymyxin antibiotic for inhibiting a sensitive strain, or a composition comprising the same in combination with a polymyxin antibiotic for preparing a compound pharmaceutical preparation for human or animal use in the treatment of a disease caused by a gram-negative bacterial infection or the preparation a growth-promoting feed additive and for the raising of livestock animals.
Disclosed is the use of an N-acetylglycylglutamine in animal feed additives, which belongs to the field of feed additives. In particular, disclosed is the use of a glutamine derivative, or a racemate, stereoisomer, geometric isomer, tautomer, solvate, or a feed acceptable salt thereof, which substance has stable physical and chemical properties and a good animal palatability, in the preparation of animal feed additives and animal breeding. The glutamine derivative is N-acetylglycyl-glutamine, and can be used, in animal breeding, as a glutamine substitution or a glycylglutamine substitution derived from a glutamine donor, or as an amino acid dipeptide donor or an amino acid tripeptide.
Disclosed is the use of butyryl glycine and a derivative thereof in the preparation of an animal feed additive. Butyryl glycine is used in animal breeding experiments, and significantly improves the production performance of animals in terms of improvements in the weight gain rate of the average daily gain and the feed conversion rate. Butyryl glycine metal salts are used in animal breeding experiments, and compared to the butyryl glycine experiment group, have a similar efficacy for the production performance of animals. Farmers can feed animals with a butyryl glycine feed additive or a butyryl glycine derivative feed additive along with feeds, thus significantly improving the weight gain rate of the average daily gain and the feed conversion rate in postweaning pigs, and thus having broad application prospects.
Disclosed are an N,N-dimethylglycine organic acid polyvalent metal ion compound salt or a solvate thereof, and an application thereof in preparation of novel feed additives and feeds. Also disclosed is a feeding composition comprising the N,N-dimethylglycine organic acid polyvalent metal ion compound salt or the solvate thereof. Applying the N,N-dimethylglycine organic acid polyvalent metal ion compound salt or the solvate thereof in animal farming industry achieves the effects of improving the animal production performance, such as increasing animal weight gain rate and reducing a feed conversion ratio. The N,N-dimethylglycine organic acid polyvalent metal ion compound salt has a similar or better effect than an N,N-dimethylglycine sodium salt.
C07C 229/12 - Composés contenant des groupes amino et carboxyle liés au même squelette carboné ayant des groupes amino et carboxyle liés à des atomes de carbone acycliques du même squelette carboné le squelette carboné étant acyclique et saturé ayant un seul groupe amino et un seul groupe carboxyle liés au squelette carboné l'atome d'azote du groupe amino étant lié de plus à des atomes de carbone acycliques ou à des atomes de carbone de cycles autres que des cycles aromatiques à six chaînons à des atomes de carbone de squelettes carbonés acycliques
C07C 227/16 - Préparation de composés contenant des groupes amino et carboxyle liés au même squelette carboné à partir de composés contenant déjà des groupes amino et carboxyle ou leurs dérivés par des réactions n'impliquant pas les groupes amino ou carboxyle
322n21818 linear fatty acid, or an aromatic acid. The conjugate salt of N,N-dimethylglycine and a metal organic acid is formed by forming a salt using N,N-dimethylglycine and metal ions, and on this basis, introducing another organic acid having a hydrophobic group to form a conjugate acid salt, so that the affinity of the salt to water molecules in air is decreased or the affinity or absorption of molecular aggregates, formed by crystal form behaviors, of the salt to the water molecules in air is decreased, thereby improving the moisture absorption of N,N-dimethylglycine.
C07C 229/12 - Composés contenant des groupes amino et carboxyle liés au même squelette carboné ayant des groupes amino et carboxyle liés à des atomes de carbone acycliques du même squelette carboné le squelette carboné étant acyclique et saturé ayant un seul groupe amino et un seul groupe carboxyle liés au squelette carboné l'atome d'azote du groupe amino étant lié de plus à des atomes de carbone acycliques ou à des atomes de carbone de cycles autres que des cycles aromatiques à six chaînons à des atomes de carbone de squelettes carbonés acycliques
C07C 227/16 - Préparation de composés contenant des groupes amino et carboxyle liés au même squelette carboné à partir de composés contenant déjà des groupes amino et carboxyle ou leurs dérivés par des réactions n'impliquant pas les groupes amino ou carboxyle
C07C 227/18 - Préparation de composés contenant des groupes amino et carboxyle liés au même squelette carboné à partir de composés contenant déjà des groupes amino et carboxyle ou leurs dérivés par des réactions impliquant des groupes amino ou carboxyle, p. ex. hydrolyse d'esters ou d'amides, par formation d'halogénures, de sels ou d'esters
Provided is a method of using a copper-calcium sulphate as an animal feed additive. When used in animal breeding, a low dose of the copper-calcium sulphate can achieve the effect of that high dosage of copper sulphate achieve in the promotion of animal growth, and thus the copper-calcium sulphate can be used as an animal basic nutritional supplement to substitute low-copper preparations in the breeding of poultry, livestock or aquatic animals. Copper-calcium sulphate, used as a novel, efficient and safe feed additive in the feed processing industry and animal breeding industry, can reduce the dosage of copper ion by nearly 50-70% to achieve the same production performance, can significantly reduce the use of copper in animal husbandry, and can reduce the production costs, reduce the toxic side effects of a high level of copper, and reduce the environmental pollution, thus the copper-calcium sulphate is a copper compound with unique advantages.
A23K 20/24 - Composés de métaux alcalino-terreux, p. ex. de magnesium
A23K 50/20 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les chevaux
A23K 50/10 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les ruminants
A23K 50/75 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les oiseaux pour la volaille
A23K 50/30 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les porcs
A23K 50/40 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux carnivores, p. ex. pour les chats ou les chiens
A23K 50/80 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux aquatiques, p. ex. pour les poissons, les crustacés ou les mollusques
A23K 20/20 - Substances inorganiques, p. ex. oligo-éléments
A23K 50/50 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les rongeurs
14.
Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs
Disclosed are derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs. The derivatives have structural formulae as shown in formulae (I) to (VI). The derivatives of 1H-imidazole-4,5-dicarboxamide as disclosed in the present invention have significant anticoccidial effect, especially against coccidia that show a resistance to other anticoccidial drugs, and thus they can be used in preparation of anticoccidial drug.
Disclosed are a pharmaceutical composition comprising a polymyxin synergist and the use thereof. The oxygen-containing hydrocarbon derivative containing 4 to 18 carbon atoms includes a fatty alcohol, a fatty acid and a fatty acid glyceride and serves as a polymyxin synergist, in particular as a synergist for a strain sensitive to the polymyxin inhibiting effect and as a drug-resistance reversal agent for polymyxin. Also disclosed is a pharmaceutical composition of the polymyxin synergist. The pharmaceutical composition is further used for preparing a drug and an animal feed additive for the treatment of a disease caused by polymyxin-sensitive bacterial infection or drug-resistant bacterial infection, and provides a more effective application space for the use of polymyxin, and is of great importance in application in the fields of pharmaceutics and animal breeding.
A compound feeding composition and an application thereof in preparation of an animal feed additive. The compound feeding composition comprises a butyric acid derivative, a myristic acid derivative and a benzoate. The compound feeding composition may significantly improve the production performance of animals, prevent and treat animal diarrhea symptoms, reaching or exceeding the results of traditional feeding antibiotics and high-copper or high-zinc feed additives.
Provided are applications of a myristic acid derivative in preparing an animal growth promoter. The myristic acid derivative comprises a salt of myristic acid and a glyceryl ester of myristic acid. The myristic acid derivative has significant inhibitory activities with respect to common infectious bacteria of animals, provides great effects in terms of controlling the rate of diarrhea in animals and improving production performance in animal farming, and is applicable in farmed animals such as livestock, poultry, and aquatic products.
An application of calcium benzoate for the preparation of a feed additive. Calcium benzoate has significant effects in promoting animal production performance and preventing animal diarrhoea, and is suitable for all stages of growth of livestock, poultry, and aquatic animal breeding, having very good prospects for application in the breeding industry.
A feed composition and applications thereof in preparing an animal feed additive. The composition comprises a butyric acid derivative and a myristic acid derivative, wherein the butyric acid derivative is selected from a salt of butyl acid or an ester of butyl acid, and the myristic acid derivative is selected from a salt of myristic acid or an ester of myristic acid, where the mass ratio of the two in the feed composition is 4-1 : 1. The feed composition is applicable as an animal growth promoter, replaces a feed antibiotic or a high-dosage zinc preparation or a copper preparation, and is applicable in farmed animals comprising livestock, poultry, and aquatic products.
Disclosed is a use of a copper-calcium sulphate as an animal feed additive. The copper-calcium sulphate, when used in animal breeding at low doses, can achieve the effect that high doses of copper sulphate achieve in the promotion of animal growth, and can replace low-dose copper preparations as the basic nutritious copper element for animals used in the breeding of poultry, livestock or aquatic animals. The copper-calcium sulphate can be used as a novel, efficient and safe feed additive in the feed processing industry and animal breeding industry, can reduce the dosage of copper ions by nearly 50-70% to achieve the same production performance, can significantly reduce the use of copper in animal husbandry, and can reduce production costs, reduce the toxic side effects of a high level of copper, and reduce environmental pollution, and is a copper compound with unique advantages.
A23K 20/24 - Composés de métaux alcalino-terreux, p. ex. de magnesium
A23K 20/20 - Substances inorganiques, p. ex. oligo-éléments
A23K 50/10 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les ruminants
A23K 50/20 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les chevaux
A23K 50/30 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les porcs
A23K 50/40 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux carnivores, p. ex. pour les chats ou les chiens
A23K 50/50 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les rongeurs
A23K 50/75 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les oiseaux pour la volaille
A23K 50/80 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux aquatiques, p. ex. pour les poissons, les crustacés ou les mollusques
21.
APPLICATION OF N-BENZYLIMIDAZOLECARBOXAMIDE DERIVATIVES AS SYNERGIST FOR POLYMYXIN ANTIBIOTICS
The present invention discloses the application of N-benzylimidazolecarboxamide derivatives as synergist for polymyxin antibiotics. N-benzylimidazolecarboxamide derivatives have synergistic effects for polymyxin antibiotics in the prevention and control of livestock and poultry diseases and in the improvement of the growth and production of livestock and poultry, and can be used in the field of the prevention and control of livestock and poultry diseases and the promotion of livestock and poultry growth to improve animal production performance and thus enhance the economic benefits of livestock and poultry farming. On the other hand, the combination of N-benzylimidamide derivatives and polymyxin antibiotics can reduce the dose of polymyxin antibiotics so as to reduce toxic and side effect and improve the use efficiency and use scope of polymyxin antibiotics in human pharmaceutic field.
A61K 31/4174 - Arylalkylimidazoles, p. ex. oxymétazoline, naphazoline, miconazole
C07D 233/64 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, non condensés avec d'autres cycles comportant deux liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des radicaux hydrocarbonés substitués, liés aux atomes de carbone du cycle, p. ex. histidine
Disclosed are applications of a quinoxaline-1,4-dioxide derivative as a colistin sulfate synergist. The quinoxaline-1,4-dioxide derivative is used as a colistin sulfate collaborative synergist and the compound is used jointly with colistin sulfate in treatment of an animal disease to provide a treatment method for bacterial infectious diarrhea in animals. The colistin sulfate collaborative synergist provided in the present invention is capable of significantly increasing the therapeutic effects of colistin sulfate, is a novel, highly efficient, and safe non-antibiotic colistin sulfate collaborative synergist, is applicable in disease prevention and treatment for animal farming, and increases economic benefits for the farming industry.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Preparations of microorganisms for medical or veterinary
use; preparations of trace elements for human and animal
use; nutritional supplements; mineral food supplements;
medicated animal feed; dietary supplements for animals;
chemical preparations for veterinary purposes; medicines for
veterinary purposes; veterinary preparations; biological
preparations for veterinary purposes.
24.
USE OF SUBSTITUTED BENZOGUANIDINE DERIVATIVE AS POLYMYXIN ANTIBIOTIC SYNERGIST
The present invention discloses the use of a substituted benzoguanidine derivative as a polymyxin antibiotic synergist, particularly as a synergist and a drug resistance reversal agent of the polymyxin antibiotic for inhibiting a sensitive strain. The present invention also provides a substituted benzoguanidine derivative or a composition comprising the same in combination with a polymyxin antibiotic for preparing a compound pharmaceutical preparation for human or animal use in the treatment of a disease caused by a gram-negative bacterial infection or the preparation a growth-promoting feed additive and for the raising of livestock animals.
Disclosed are monoesters, inner complex salts or monoester salts of hexahydro-β-acid, and application thereof as animal feed additives. The compounds as shown in formula (I), (II) and (III) show low toxicity or non-toxicity to animals, and have higher stability and better growth promotion effects than those disclosed in other patents, which make them more suitable to be applied as growth promoters used in feed and have a very good application prospect in cultivation industry.
C07C 49/713 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes hydroxyle un groupe cétone faisant partie d'un cycle à six chaînons
Mash for fattening livestock; by-products of the processing of cereals, for livestock consumption; livestock fattening preparations namely, livestock food, excluding wildlife seed mixes; beverages for pets
27.
Diaminoguanidine derivatives and application thereof in preparation of animal growth promoters used in feed
1 is methyl, ethyl, isopropyl, n-butyl, n-propyl, n-pentyl, n-octyl, n-tetradecyl, sec-butyl, 3-pentyl, cyclopentyl or benzyl. The diaminoguanidine compounds significantly improve the productivity of ducks if they are fed with the diaminoguanidine compounds. Productivity of pigs or chickens is also improved with such diaminoguanidine compounds.
C07C 281/18 - Composés contenant l'un des groupes p. ex. aminoguanidine l'autre atome d'azote étant lié de plus par une liaison double à un atome de carbone, p. ex. guanylhydrazones
A23K 50/75 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les oiseaux pour la volaille
A23K 50/30 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les porcs
28.
Esters or salts of 2-hydroxy-4-propylcyclohepta-2,4,6-trienone and application thereof in preparation of animal antibacterial agents and growth promoters used in feed
Esters or salts of 2-hydroxy-4-propyleyclohepta-2,4,6-trienone, and applications thereof in preparation of animal antibacterial agents and growth promoters used in feed. The esters or salts of 2-hydroxy-4-propylcyclohepta-2,4,6-trienone has a structural formula as shown in formula 1 or 2: in formula 1, R1 represents heptadecyl; and in formula 2, L is sodium, potassium, calcium, magnesium, zinc, copper or manganese. The esters or salts of 2-hydroxy-4-propyleyclohepta-2,4,6-trienone, as shown in formula 1 or 2, have high stability and safety, and good antibacterial and growth promotion effects, which make them preferable to be used as animal antibacterial agents and growth promoters in feed, and have a very good application prospect in the cultivation industry.
C07C 69/74 - Esters d'acides carboxyliques dont un groupe carboxyle est lié à un atome de carbone d'un cycle autre qu'un cycle aromatique à six chaînons
C07C 69/24 - Esters d'acides acycliques monocarboxyliques saturés dont le groupe carboxyle est lié à un atome de carbone acyclique ou à l'hydrogène avec au moins trois atomes de carbone dans la partie acide estérifiés par des composés monohydroxylés
C07C 49/717 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes hydroxyle un groupe cétone faisant partie d'un cycle de sept à douze chaînons
Disclosed are a glycalpyramide derivative and an application thereof in preparation of an anticoccidial drug. A structural formula of the glycalpyramide derivative is shown in formulae from Formula (I) to Formula (VI). The glycalpyramide derivative of the present invention has a remarkable anticoccidial effect, particularly on certain coccidia having drug resistance to other anticoccidial drugs, and therefore the glycalpyramide derivative can be applied to preparation of anticoccidial drugs. The invention provides conditions for developing novel anticoccidial drugs.
A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p. ex. clozapine, dilazèpe
Isopropoxy-benzoguanamine series salt as shown by the formula (I) and an application thereof in preparing a growth promoter for animal feed, wherein R is DL-lactic acid, methanesulfonic acid, 2-isethionic acid, citric acid, tartaric acid, benzoic acid, succinic acid, fumaric acid, maleic acid, acetic acid, sulfuric acid, phosphoric acid, or oxalic acid.
C07C 281/18 - Composés contenant l'un des groupes p. ex. aminoguanidine l'autre atome d'azote étant lié de plus par une liaison double à un atome de carbone, p. ex. guanylhydrazones
31.
ROBENIDINE SERIES SALT AND APPLICATION THEREOF IN PREPARING GROWTH PROMOTER FOR ANIMAL FEED
Disclosed are a robenidine series salt and an application thereof in preparing a growth promoter for animal feed. The structural formula of the robenidine series salt is shown in formula (I): R is DL-lactic acid, methanesulfonic acid, 2-isethionic acid, citric acid, tartaric acid, benzoic acid, succinic acid, fumaric acid, maleic acid, acetic acid, sulfuric acid, phosphoric acid, or oxalic acid.
Disclosed in the present invention are a hexahydro beta-acid di-fatty acid ester and an application thereof as an animal feed additive. The hexahydro beta-acid di-fatty acid ester (R1 = isopropyl, isobutyl or 2-butyl; R2 = any alkyl from methyl to heptadecyl) shown in formula (I) of the present invention is low-toxic or non-toxic to livestock and poultry, and is suitable for use as a growth promoter in animal feed, with excellent prospects for application in the farming industry.
C07C 69/16 - Esters d'acide acétique de composés dihydroxylés
C07C 69/28 - Esters d'acides acycliques monocarboxyliques saturés dont le groupe carboxyle est lié à un atome de carbone acyclique ou à l'hydrogène avec au moins trois atomes de carbone dans la partie acide estérifiés par des composés dihydroxylés
33.
APPLICATION OF P-METHYL BENZOIC ACID OR SALT THEREOF AS ANIMAL FEED ADDITIVE
An application of p-methyl benzoic acid and salt thereof in animal feed or drinking water of farm animals such as pigs, broiler chickens, ducks, and aquaculture can prevent diarrhoea and promote growth, and is a type of growth promoting acidifying agent.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
31 - Produits agricoles; animaux vivants
Produits et services
Veterinary preparations; medicines for veterinary purposes;
chemical preparations for veterinary purposes; enzyme
preparations for veterinary purposes; biological
preparations for veterinary purposes; enzymes for veterinary
purposes; dietary supplements for animals; cultures of
microorganisms for medical and veterinary use. Animal foodstuffs; animal fattening preparations; fodder;
mash for fattening livestock; by-products of the processing
of cereals, for animal consumption; livestock fattening
preparations; strengthening animal forage; cattle food;
stall food for animals; beverages for pets.
35.
APPLICATION OF ZINC DECANOATE AS ANIMAL FEED ADDITIVE
Disclosed is the application of zinc decanoate as a feed additive and a feed-use growth promoter, and especially its application in pig feed as a substitute for a high dose of zinc oxide; zinc decanoate reduces the use of zinc in animal husbandry and can decrease production costs, while also reducing the toxic side effects of high levels of zinc.
Provided is the application of myristic acid copper as a feed additive and a feed-use growth promoter, particularly as an effective substitute for copper sulfate; 1-200 ppm of the additive are added to animal feed (calculated by copper ion content), and the growth promoting effectiveness of each dosage level is superior to that of other copper compounds having an equal dose of copper. At the same time, a low dose of myristic acid copper may be substituted for the growth promoting effect of a high dose of copper in a copper sulfate source.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Nutritional supplements, namely, probiotic compositions for animal use; Bacteriological preparations for animal use; Cultures of microorganisms for animal use; Mineral supplements, namely, trace elements for animal use
38.
MONOESTERS, INNER COMPLEX SALTS OR MONOESTER SALTS OF HEXAHYDRO-"BETA"-ACID AND APPLICATION THEREOF AS ANIMAL FEED ADDITIVES
The invention discloses monoesters, inner complex salts or monoester salts of hexahydro-.beta.-acid, and application thereof as animal feed additives. The compounds of the present invention as shown in formula (I), (II) and (III) show low toxicity or non-toxicity to animals, and have higher stability and better growth promotion effects than those disclosed in other patents, which make them more suitable to be applied as growth promoters used in feed and have a very good application prospect in cultivation industry.
C07C 45/77 - Préparation de chélates d'aldéhyde ou de cétone
C07C 49/713 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes hydroxyle un groupe cétone faisant partie d'un cycle à six chaînons
C07C 67/28 - Préparation d'esters d'acides carboxyliques par modification de la partie hydroxyle de l'ester sans introduction d'un groupe ester
C07C 69/16 - Esters d'acide acétique de composés dihydroxylés
C07C 69/28 - Esters d'acides acycliques monocarboxyliques saturés dont le groupe carboxyle est lié à un atome de carbone acyclique ou à l'hydrogène avec au moins trois atomes de carbone dans la partie acide estérifiés par des composés dihydroxylés
39.
HEXAHYDROCOLUPULONE MONOESTER, INNER COMPLEX SALT OR MONOESTER SALT, AND APPLICATION THEREOF AS ANIMAL FEED ADDITIVE
Provided are a hexahydrocolupulone monoester, an inner complex salt or a monoester salt, and an application thereof as an animal feed additive. The compounds as shown in formula 1, formula 2 and formula 3 of the present invention are low in toxicity or are non-toxic to beasts and birds, have higher stability and stronger growth promotion performances than related compounds covered by current patents, and thus are more suitable for being used as a growth promoter for feeds, and have a very good application prospect in the breeding industry.
C07C 45/77 - Préparation de chélates d'aldéhyde ou de cétone
A23K 20/121 - Composés hétérocycliques contenant de l’oxygène ou du soufre comme hétéroatome
C07C 49/713 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes hydroxyle un groupe cétone faisant partie d'un cycle à six chaînons
C07C 67/28 - Préparation d'esters d'acides carboxyliques par modification de la partie hydroxyle de l'ester sans introduction d'un groupe ester
C07C 69/16 - Esters d'acide acétique de composés dihydroxylés
C07C 69/28 - Esters d'acides acycliques monocarboxyliques saturés dont le groupe carboxyle est lié à un atome de carbone acyclique ou à l'hydrogène avec au moins trois atomes de carbone dans la partie acide estérifiés par des composés dihydroxylés
40.
DIAMINOGUANIDINE DERIVATIVES AND APPLICATION THEREOF IN PREPARATION OF ANIMAL GROWTH PROMOTERS USED IN FEED
The invention discloses diaminoguanidine derivatives and application thereof in preparation of animal growth promoters used in feed. The diaminoguanidine derivatives have a structural formula as shown in formula (I), wherein R1 is methyl, ethyl, isopropyl, n-butyl, n-propyl, n-pentyl, n-octyl, n-tetradecyl, sec- butyl, 3-pentyl, cyclopentyl or benzyl. Via feeding experiments, it has been discovered for the first time by the inventors that, productivity of ducks is improved significantly if they are fed with the diaminoguanidine compounds. It has also been discovered via feeding experiments that productivity of pigs or chickens is improved with such diaminoguanidine compounds. (see formula I)
C07C 281/18 - Composés contenant l'un des groupes p. ex. aminoguanidine l'autre atome d'azote étant lié de plus par une liaison double à un atome de carbone, p. ex. guanylhydrazones
A diamino guanidine derivative as represented by formula I, wherein R1 represents methyl, ethyl, isopropyl, n-butyl, n-propyl, n-pentyl, n-octyl, n-tetradecyl, secbutyl, 3-pentyl, cyclopentyl or benzyl. When first using the compound in feeding experiments it was found that, applied to ducks, productivity was clearly improved. With similar feeding experiments, productivity of pigs and chickens was also improved. The diamino guanidine derivative can be used in preparing animal feed growth promoter.
C07C 281/18 - Composés contenant l'un des groupes p. ex. aminoguanidine l'autre atome d'azote étant lié de plus par une liaison double à un atome de carbone, p. ex. guanylhydrazones
A 2-hydroxyl-4-n-propyl-1-tropone ester or salt compound represented by formula 1 or formula 2. R1 in formula 1 represents n-heptadecyl, and L in formula 2 is sodium, potassium, calcium, magnesium, zinc, copper or manganese. The 2-hydroxyl-4-n-propyl-1-tropone ester or salt compound has high stability and safety and good antibacterial and growth promotion effects, and thus is more suitable for use as a special antibacterial agent for animals and a growth promoter for feed, and has a great application prospect in the farming industry.
C07C 69/24 - Esters d'acides acycliques monocarboxyliques saturés dont le groupe carboxyle est lié à un atome de carbone acyclique ou à l'hydrogène avec au moins trois atomes de carbone dans la partie acide estérifiés par des composés monohydroxylés
C07C 67/14 - Préparation d'esters d'acides carboxyliques à partir d'halogénures d'acides carboxyliques
C07C 49/717 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes hydroxyle un groupe cétone faisant partie d'un cycle de sept à douze chaînons
C07C 45/61 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogènePréparation des chélates de ces composés par des réactions ne créant pas de groupe C=O
A61K 31/222 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine avec des composés ayant des groupes aromatiques, p. ex. dipivéfrine, ibopamine
A61K 31/122 - Cétones ayant l'atome d'oxygène lié directement à un cycle, p. ex. quinones, vitamine K1, anthraline
Disclosed are a β-hinokitiol ester or salt and an application thereof in preparing an animal feed additive. The structural formula of the β-hinokitiol ester or salt compound is shown in formula 1 or formula 2. R1 in formula 1 is n-nonyl or n-heptadecyl, and L in formula 2 is sodium, potassium, calcium, magnesium, zinc, copper or manganese. The β-hinokitiol ester and salt compounds shown in formula 1 and formula 2 are less toxic or non-toxic to livestock, have higher safety, higher stability and better growth promotion performance than those of relevant compounds covered in the current patents, and thus are more suitable for use as a growth promoter for feed and have a great application prospect in the farming industry.
C07C 69/24 - Esters d'acides acycliques monocarboxyliques saturés dont le groupe carboxyle est lié à un atome de carbone acyclique ou à l'hydrogène avec au moins trois atomes de carbone dans la partie acide estérifiés par des composés monohydroxylés
C07C 49/717 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes hydroxyle un groupe cétone faisant partie d'un cycle de sept à douze chaînons
C07C 67/14 - Préparation d'esters d'acides carboxyliques à partir d'halogénures d'acides carboxyliques
C07C 45/61 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogènePréparation des chélates de ces composés par des réactions ne créant pas de groupe C=O
A23K 1/16 - additionnés d'éléments nutritifs accessoires; Blocs de sel
44.
Β-HINOKITOL DERIVATIVE AND USES THEREOF IN PREPARATION OF SPECIAL ANTIBACTERIAL AGENT FOR ANIMAL AND ANTIMICROBIAL GROWTH PROMOTER FOR FEED
A β-hinokitol derivative and application thereof in preparation of a special antibacterial agent for an animal and an antimicrobial growth promoter for a feed. A structural formula of the β-hinokitol derivative is shown as a formula (I), R being an n-propyl group, an n-amyl group, a benzyl group, sec-butyl, ethyl, normal-butyl, 4-chlorobenzyl, 4-fluorobenzyl, n-octyl, 1-fluoropropyl or n-tetradecanamide.
C07C 49/717 - Composés non saturés comportant un groupe cétone faisant partie d'un cycle contenant des groupes hydroxyle un groupe cétone faisant partie d'un cycle de sept à douze chaînons
A61K 31/122 - Cétones ayant l'atome d'oxygène lié directement à un cycle, p. ex. quinones, vitamine K1, anthraline
A23K 1/16 - additionnés d'éléments nutritifs accessoires; Blocs de sel
45.
Β-ACID MONOESTER SALT AND USES THEREOF SERVING AS ANIMAL FEED ADDITIVE
Disclosed are a β-acid monoester salt and uses thereof serving as an animal feed additive. The β-acid monoester salt has higher stability and can promote growth of livestock.
Provided is an application of copper 2-hydroxybenzoate as a substitute for high-dose copper for use in feed. Compared with copper sulfate, application of copper 2-hydroxybenzoate in an animal feed allows the amount of copper ions used to be reduced by nearly 75% while achieving an identical production performance, thus reducing toxic side effects of high-dose copper, reducing production costs, reducing environmental pollution, and providing a broad application prospect.
An application of zinc 2-hydroxybenzoate as a substitute for high-dose zinc oxide for use in feed, allowing for the amount of zinc oxide used to be reduced by nearly 80% while achieving an identical production performance, thus significantly reducing the application of zinc in animal husbandry, reducing production costs, reducing toxic side effects of high-dose zinc, and reducing environmental pollution.
The present invention discloses a fluoroethyl thiamine or salts thereof and application thereof in preparation of anticoccidial drugs. The structural formula of the fluoroethyl thiamine or salts thereof is shown as Formula (I). The fluoroethyl thiamine or salts thereof of the present invention have a remarkable anticoccidial effect, particularly on some coccidia which had resistance to other anticoccidial drugs, therefore the fluoroethyl thiamine or salts thereof of the present invention can be applied to preparation of anticoccidial drugs. Thus, the present invention provides conditions for development of new anticoccidial drugs.
C07D 415/00 - Composés hétérocycliques contenant le squelette de la thiamine
C07D 417/06 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
A23K 1/16 - additionnés d'éléments nutritifs accessoires; Blocs de sel
49.
USE OF ENROFLOXACIN SALT IN PREPARING SWINE ORAL PREPARATION
Disclosed in the present invention is the use of an enrofloxacin salt in preparing a swine oral preparation. The enrofloxacin salt is at least one of those salts formed by enrofloxacin and a metal ion, wherein the metal ion is zinc, copper, calcium, magnesium, iron, cobalt, manganese, chromium, silver or nickel. The enrofloxacin salt of the present invention formed by enrofloxacin and a metal ion may significantly improve the palatability of enrofloxacin for swine, and both a pharmacokinetic test and an artificial morbidity and treatment test show that the enrofloxacin salt of the present invention formed by enrofloxacin and a metal ion does not affect the bioavailability thereof, and therefore can be developed into an oral preparation via the route of digestive tract administration for swine production without affecting the normal ingestion of food by swine.
A61K 31/22 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine
C07C 69/035 - Esters d'acides acycliques monocarboxyliques saturés dont le groupe carboxyle est lié à un atome de carbone acyclique ou à l'hydrogène estérifiés par des composés hydroxylés dont le groupe hydroxyle estérifié est lié à un atome de carbone d'un cycle aromatique à six chaînons
A23K 1/16 - additionnés d'éléments nutritifs accessoires; Blocs de sel
A23K 1/18 - spécialement conçus pour des animaux déterminés
51.
APPLICATION OF P-THYMOL AND ITS SALT OR ESTER DERIVATIVE AS ANIMAL FEED ADDITIVES
Use of p-thymol and its salt or ester derivative as animal feed additive. The p-thymol, with the chemical name of 3-methyl-4-isopropyl phenol, is an isomer of thymol. The salt derivative comprises at least one of salt formed by p-thymol and metal ion, p-thymol ammonium formed by p-thymol and ammonium and resin salt formed by p-thymol and anion resin. The ester derivative comprises the ester formed by thymol and different carboxylic acid. The p-thymol and its salt or ester derivative, compared with thymol and carvacrol, has stronger antibacterial activity, lower volatility, higher safety and lower irritant, and has better palatability and growth developing effect as animal growth-promoting feed additive.
