A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/616 - Acide salicyliqueSes dérivés ayant le groupe hydroxyle en position 2 estérifié, p. ex. acide salicylsulfurique par des acides carboxyliques, p. ex. acide acétylsalicylique
A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
A61P 15/08 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs pour les troubles gonadiques ou pour augmenter la fertilité, p. ex. inducteurs d'ovulation ou de spermatogénèse
3.
METHODS OF IDENTIFYING STRAINS ASSOCIATED WITH THE HUMAN FEMALE GENITOURINARY TRACT
Provided are methods of identifying bacterial strains capable of colonizing the human female genitourinary tract and compositions thereof, as well as methods of defining vaginal microbial communities and profiles.
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
4.
MICROBIAL CONSORTIA FOR TREATING VAGINAL CONDITIONS
Provided are compositions of microbial consortia comprising a defined population of isolated lactobacilli configured to promote engraftment in a female genitourinary tract of a subject. Further provided herein are methods of administering the microbial consortia to the genitourinary tract of the subject.
Provided are compositions of microbial consortia comprising a defined population of isolated lactobacilli configured to promote engraftment in a female genitourinary tract of a subject. Further provided herein are methods of administering the microbial consortia to the genitourinary tract of the subject.
The invention relates to a pharmaceutical composition for use in treating inflammation in the female genitourinary tract of a human subject, wherein the female subject exhibits a dysbiotic microbiota in the genitourinary tract. The pharmaceutical composition comprises a substantially complete vaginal microbiota preparation, wherein the preparation (i) comprises one, two, three or four bacterial species from the genus Lactobacillus, selected from Lactobacillus crispatus, Lactobacillus iners, Lactobacillus jensenii, Lactobacillus gasseri, which comprise about 80-99.9% of all detectable bacterial species of the preparation; and (ii) comprises less than 5% of Gardnerella spp., Atopobium spp., and Prevotella spp.; wherein the pharmaceutical composition comprises a pharmaceutically acceptable carrier or diluent. The invention further relates to a method of preparing said composition, and devices comprising and/or using the same.
A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
Provided are methods of identifying bacterial strains capable of colonizing the human female genitourinary tract and compositions thereof, as well as methods of defining vaginal microbial communities and profiles.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceuticals and medicinal preparations for medical and
veterinary use for the treatment of diseases, ailments and
dysbiosis associated with the microbiome; pharmaceutical and
medicinal preparations for the prevention and treatment of
disorders and dysbiosis in the reproductive and urogenital
organs; dietary and nutritional supplements and nutritional
food additives for the maintenance of health and prevention
of disease; pharmaceutical and medicinal preparations for
the prevention and treatment of disease in connection with
immune response; pharmaceutical and biopharmaceutical
preparations for the prevention and treatment of human
diseases, namely, infectious disease, autoimmune disease,
inflammatory disease, immune disorders, allergic disorders,
cancer, immuno-oncology, metabolic disorders, gynecological
disorders, reproductive disorders, cardiovascular disorders,
and endocrine disorders; compositions and preparations
comprised of microorganisms or cultures of microorganisms,
namely, bacteria or bacterial derived products for medical
and veterinary use; diagnostic agents for medical purposes,
namely for assessing human or animal microbial communities
and disturbances thereof; diagnostic kits comprising medical
diagnostic reagents and assays that test for the presence of
biomarkers to determine overall health and microbiome
health; none of the aforementioned for use in the field of
enteral nutrition or intravenous therapy. Pharmaceutical research and development; pharmaceutical
research and development in the fields of microbiologics,
immunotherapeutics, and other therapeutic agents; scientific
research and development services relating to
pharmaceuticals, diagnostics, food additives, dietary
supplements, medical foods, foods for special dietary use,
suppositories, topical creams, and sanitary products,
namely, sanitary towels, sanitary napkins, tampons, sanitary
panties, panty shields, panty liners, sanitary pads;
providing medical and scientific research information in the
field of pharmaceuticals and clinical trials; medical and
scientific research, namely, conducting clinical trials for
others; laboratory research services relating to
pharmaceuticals; scientific and technological services, and
consultancy relating thereto in the field of development,
manufacturing and testing of pharmaceuticals and
biopharmaceuticals; providing product research and
development in the pharmaceutical field for purposes of
process development, validation, qualification, and
manufacturing of pharmaceuticals and biopharmaceuticals;
research and development in prenatal and postnatal care;
quality evaluation and testing of pharmaceutical,
biopharmaceutical and chemical products; providing reagent
sample testing and analysis services; providing access to a
collection of human biological materials for research
purposes. Medical screening services of biological materials;
biological material bank services; collection and
preservation of human and animal biological materials.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Oral contraceptives; pharmaceutical products; pharmaceutical
preparations; dietary foods and substances adapted for
medical use; nutritional supplements for humans; nutritional
supplements; nutritional supplements for medical use;
pharmaceutical drugs; vitamin preparations; nutritional,
dietary and mineral supplements and vitamins for health
improvement; pharmaceutical preparations for use in the
field of gynecology and women's health; pharmaceutical
preparations and substances for use in gynecology.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceuticals and medicinal preparations for medical use for the treatment of diseases, ailments and dysbiosis associated with the microbiome; Pharmaceutical and medicinal preparations for the prevention and treatment of diseases, ailments, and dysbiosis in the reproductive and urogenital organs; Pharmaceutical and medicinal preparations for the prevention and treatment of diseases and ailments in connection with immune response; Pharmaceutical and medicinal preparations for the prevention and treatment of human diseases and ailments, namely, infectious disease, autoimmune disease, inflammatory disease, immune disorders, allergic disorders, cancer, immuno-oncology, gynecological disorders, reproductive disorders, and endocrine disorders; probiotic compositions and probiotic preparations for medical use, comprised of microorganisms or cultures of microorganisms, namely, vaginal bacteria or vaginal bacteria-derived products; Diagnostic agents for medical purposes, namely, diagnostic agents for assessing human microbial communities and disturbances thereof; Diagnostic kits consisting primarily of medical diagnostic reagents and assays that test for the presence of biomarkers to determine overall health and microbiome health
14.
VAGINAL MICROBIOTA-ASSOCIATED METHODS, COMPOSITIONS, AND DEVICES
The invention relates to a pharmaceutical composition for use in treating inflammation in the female genitourinary tract of a human subject, wherein the female subject exhibits a dysbiotic microbiota in the genitourinary tract. The pharmaceutical composition comprises a substantially complete vaginal microbiota preparation, wherein the preparation(i) comprises one, two, three or four bacterial species from the genus Lactobacillus, selected from Lactobacillus crispatus, Lactobacillus iners, Lactobacillus jensenii, Lactobacillus gasseri, which comprise about 80-99.9% of all detectable bacterial species of the preparation; and(ii) comprises less than 5% of Gardnerella spp., Atopobium spp., and Prevotella spp.; wherein the pharmaceutical composition comprises a pharmaceutically acceptable carrier or diluent. The invention further relates to a method of preparing said composition, and devices comprising and/or using the same.
A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
A61P 15/02 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs pour les pathologies du vagin
15.
VAGINAL MICROBIOTA-ASSOCIATED METHODS, COMPOSITIONS, AND DEVICES
The invention relates to a pharmaceutical composition for use in treating inflammation in the female genitourinary tract of a human subject, wherein the female subject exhibits a dysbiotic microbiota in the genitourinary tract. The pharmaceutical composition comprises a substantially complete vaginal microbiota preparation, wherein the preparation(i) comprises one, two, three or four bacterial species from the genus Lactobacillus, selected from Lactobacillus crispatus, Lactobacillus iners, Lactobacillus jensenii, Lactobacillus gasseri, which comprise about 80-99.9% of all detectable bacterial species of the preparation; and(ii) comprises less than 5% of Gardnerella spp., Atopobium spp., and Prevotella spp.; wherein the pharmaceutical composition comprises a pharmaceutically acceptable carrier or diluent. The invention further relates to a method of preparing said composition, and devices comprising and/or using the same.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Pharmaceuticals and medicinal preparations for medical and veterinary use for the treatment of diseases, ailments and dysbiosis associated with the microbiome; Pharmaceutical and medicinal preparations for the prevention and treatment of disorders and dysbiosis in the reproductive and urogenital organs; Dietary and nutritional supplements and nutritional food additives for the maintenance of health and prevention of disease; Pharmaceutical and medicinal preparations for the prevention and treatment of disease in connection with immune response; Pharmaceutical and biopharmaceutical preparations for the prevention and treatment of human diseases, namely, infectious disease, autoimmune disease, inflammatory disease, immune disorders, allergic disorders, cancer, immuno-oncology, metabolic disorders, gynecological disorders, reproductive disorders, cardiovascular disorders, and endocrine disorders; Compositions and preparations comprised of microorganisms or cultures of microorganisms, namely, bacteria or bacterial derived products for medical and veterinary use; Diagnostic agents for medical purposes, namely for assessing human or animal microbial communities and disturbances thereof; Diagnostic kits comprising medical diagnostic reagents and assays that test for the presence of biomarkers to determine overall health and microbiome health; none of the aforementioned for use in the field of enteral nutrition or intravenous therapy. Pharmaceutical research and development; Pharmaceutical research and development in the fields of microbiologics, immunotherapeutics, and other therapeutic agents; Scientific research and development services relating to pharmaceuticals, diagnostics, food additives, dietary supplements, medical foods, foods for special dietary use, suppositories, topical creams, and sanitary products, namely, sanitary towels, sanitary napkins, tampons, sanitary panties, panty shields, panty liners, sanitary pads; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; medical and scientific research, namely, conducting clinical trials for others; laboratory research services relating to pharmaceuticals; Scientific and technological services, consultation services in the field of development, manufacturing and testing of pharmaceuticals and biopharmaceuticals; providing product research and development in the pharmaceutical field for purposes of process development, validation, qualification, and manufacturing of pharmaceuticals and biopharmaceuticals; Research and development in prenatal and postnatal care; Providing evaluation testing for pharmaceutical, biopharmaceutical and chemical products, Providing reagent sample testing and diagnostic services; Medical screening services of biological materials; Biological material bank services; collection and preservation of human and animal biological materials; providing access to a collection of human biological materials.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Pharmaceuticals and medicinal preparations for medical and veterinary use for the treatment of diseases, ailments and dysbiosis associated with the microbiome; Pharmaceutical and medicinal preparations for the prevention and treatment of disorders and dysbiosis in the reproductive and urogenital organs; Dietary and nutritional supplements and nutritional food additives for the maintenance of health and prevention of disease; Pharmaceutical and medicinal preparations for the prevention and treatment of disease in connection with immune response; Pharmaceutical and biopharmaceutical preparations for the prevention and treatment of human diseases, namely, infectious disease, autoimmune disease, inflammatory disease, immune disorders, allergic disorders, cancer, immuno-oncology, metabolic disorders, gynecological disorders, reproductive disorders, cardiovascular disorders, and endocrine disorders; Compositions and preparations comprised of microorganisms or cultures of microorganisms, namely, bacteria or bacterial derived products for medical and veterinary use; Diagnostic agents for medical purposes, namely for assessing human or animal microbial communities and disturbances thereof; Diagnostic kits comprising medical diagnostic reagents and assays that test for the presence of biomarkers to determine overall health and microbiome health; none of the aforementioned for use in the field of enteral nutrition or intravenous therapy. Pharmaceutical research and development; Pharmaceutical research and development in the fields of microbiologics, immunotherapeutics, and other therapeutic agents; Scientific research and development services relating to pharmaceuticals, diagnostics, food additives, dietary supplements, medical foods, foods for special dietary use, suppositories, topical creams, and sanitary products, namely, sanitary towels, sanitary napkins, tampons, sanitary panties, panty shields, panty liners, sanitary pads; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; medical and scientific research, namely, conducting clinical trials for others; laboratory research services relating to pharmaceuticals; Scientific and technological services, consultation services in the field of development, manufacturing and testing of pharmaceuticals and biopharmaceuticals; providing product research and development in the pharmaceutical field for purposes of process development, validation, qualification, and manufacturing of pharmaceuticals and biopharmaceuticals; Research and development in prenatal and postnatal care; Providing evaluation testing for pharmaceutical, biopharmaceutical and chemical products, Providing reagent sample testing and diagnostic services; Medical screening services of biological materials; Biological material bank services; collection and preservation of human and animal biological materials; providing access to a collection of human biological materials.
