Abrégé

Methods and devices are provided for fabricating and employing patient immobilization devices during radiation treatment procedures. Immobilization devices are provided that include a thin conformal shell configured to conform to an anatomical region of a patient that is to be exposed to radiation during a radiation treatment procedure, with a rigid lattice structure extending outwardly, in an external, beam-facing direction, from the conformal shell. The rigid lattice structure confers structural rigidity to the device, and the thin cellular regions mitigate the impact of the device on a surface dose delivered to the patient or subject. The present mechanical-metamaterial-based immobilization devices incorporate structural features that confer advantageous mechanical properties and radiation transmissive properties when compared with conventional solid or mesh-based immobilization devices used in radiation therapy.

Classes IPC  ?

• A61B 6/04 - Mise en position des patientsLits inclinables ou similaires
• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

Abrégé

Disclosed herein are systems, methods, and computer-readable storage devices for manufacturing patient-specific bolus for use in targeted radiotherapy treatment. Based on dose calculations without a bolus and based on three-dimensional scan data of a patient, the example system generates a model of a bolus for targeting radiotherapy treatment to a planning target volume or target region within the patient. The system can perform several iterations to generate a resulting model for the bolus. Then, the system can generate instructions for controlling a three-dimensional printer to generate the bolus that conforms to the patient's skin surface while also specifically targeting the planning target volume for the radiotherapy treatment. In this way, the amount of radiotherapy treatment administered to other tissue is reduced, while the costs, time, and human involvement in creating the bolus are significantly reduced.

Classes IPC  ?

• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• A61B 6/03 - Tomographie informatisée
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations

Abrégé

Systems and methods are provided for modelling and fabricating a patient-specific immobilization support. Image data is obtained for characterizing an exposed surface of a body portion and a support structure employed to support the body portion during imaging. The image data is processed to determine a position and orientation of the support structure based on spatial features of the support structure, and surface data associated with the exposed surface of the body portion is segmented from the image data. The segmented surface data and the position and orientation of the support structure are employed to generate a digital model of a patient-specific immobilization structure that is attachable to the support structure for immobilizing the body portion between the patient-specific immobilization structure and the support structure. Prior to fabricating the patient-specific immobilization structure, an initial digital model may be modified, optionally according to beam parameters associated with a treatment plan.

Classes IPC  ?

• A61B 90/18 - Housses de retenue, p. ex. masques d'immobilisation

Abrégé

Systems and methods are provided for modelling and fabricating a patient-specific immobilization support. Image data is obtained for characterizing an exposed surface of a body portion and a support structure employed to support the body portion during imaging. The image data is processed to determine a position and orientation of the support structure based on spatial features of the support structure, and surface data associated with the exposed surface of the body portion is segmented from the image data. The segmented surface data and the position and orientation of the support structure are employed to generate a digital model of a patient-specific immobilization structure that is attachable to the support structure for immobilizing the body portion between the patient-specific immobilization structure and the support structure. Prior to fabricating the patient-specific immobilization structure, an initial digital model may be modified, optionally according to beam parameters associated with a treatment plan.

Classes IPC  ?

• A61B 90/18 - Housses de retenue, p. ex. masques d'immobilisation
• A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci
• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

Abrégé

Systems and methods are provided for modelling and fabricating a patient-specific immobilization support. Image data is obtained for characterizing an exposed surface of a body portion and a support structure employed to support the body portion during imaging. The image data is processed to determine a position and orientation of the support structure based on spatial features of the support structure, and surface data associated with the exposed surface of the body portion is segmented from the image data. The segmented surface data and the position and orientation of the support structure are employed to generate a digital model of a patient-specific immobilization structure that is attachable to the support structure for immobilizing the body portion between the patient-specific immobilization structure and the support structure. Prior to fabricating the patient-specific immobilization structure, an initial digital model may be modified, optionally according to beam parameters associated with a treatment plan.

Classes IPC  ?

• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive

Abrégé

Systems and methods are provided for generating surface brachytherapy applicators in which catheter channel trajectories are generated laterally from both sides of a cut plane bisecting an initial model of the surface brachytherapy applicator model, thereby mitigating the effects of patient-surface-induced curvature. The catheter channels may be defined based on catheter channel trajectories that are spatially distributed, relative to the cut plane, on both sides of the cut plane, and spatially offset relative to a patient-facing surface of the surface brachytherapy applicator model. In some example embodiments, catheter channel trajectories are spaced relative to the cut plane such that neighbouring catheter channel trajectories are evenly spaced along a set of contours. Prior to fabrication, the local radius of curvature of catheter channels may be adjusted in a manual or automated manner to exceed a threshold.

Classes IPC  ?

• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• G06F 30/10 - CAO géométrique
• B33Y 80/00 - Produits obtenus par fabrication additive
• B33Y 50/00 - Acquisition ou traitement de données pour la fabrication additive
• B29C 64/386 - Acquisition ou traitement de données pour la fabrication additive
• B29L 31/00 - Autres objets particuliers
• G06Q 50/04 - Fabrication

Abrégé

Systems and methods are provided for generating surface brachytherapy applicators in which catheter channel trajectories are generated laterally from both sides of a cut plane bisecting an initial model of the surface brachytherapy applicator model, thereby mitigating the effects of patient-surface-induced curvature. The catheter channels may be defined based on catheter channel trajectories that are spatially distributed, relative to the cut plane, on both sides of the cut plane, and spatially offset relative to a patient-facing surface of the surface brachytherapy applicator model. In some example embodiments, catheter channel trajectories are spaced relative to the cut plane such that neighbouring catheter channel trajectories are evenly spaced along a set of contours. Prior to fabrication, the local radius of curvature of catheter channels may be adjusted in a manual or automated manner to exceed a threshold.

Classes IPC  ?

• A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

Abrégé

Disclosed herein are systems, methods, and computer-readable storage devices for manufacturing patient-specific bolus for use in targeted radiotherapy treatment. Based on dose calculations without a bolus and based on three-dimensional scan data of a patient, the example system generates a model of a bolus for targeting radiotherapy treatment to a planning target volume or target region within the patient. The system can perform several iterations to generate a resulting model for the bolus. Then, the system can generate instructions for controlling a three-dimensional printer to generate the bolus that conforms to the patient's skin surface while also specifically targeting the planning target volume for the radiotherapy treatment. In this way, the amount of radiotherapy treatment administered to other tissue is reduced, while the costs, time, and human involvement in creating the bolus are significantly reduced.

Classes IPC  ?

• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• A61B 6/03 - Tomographie informatisée
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• B29L 31/00 - Autres objets particuliers
• B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive
• B29K 67/00 - Utilisation de polyesters comme matière de moulage

Abrégé

Disclosed herein are systems, methods, and computer-readable storage devices for manufacturing patient-specific bolus for use in targeted radiotherapy treatment. Based on dose calculations without a bolus and based on three-dimensional scan data of a patient, the example system generates a model of a bolus for targeting radiotherapy treatment to a planning target volume or target region within the patient. The system can perform several iterations to generate a resulting model for the bolus. Then, the system can generate instructions for controlling a three-dimensional printer to generate the bolus that conforms to the patient's skin surface while also specifically targeting the planning target volume for the radiotherapy treatment. In this way, the amount of radiotherapy treatment administered to other tissue is reduced, while the costs, time, and human involvement in creating the bolus are significantly reduced.

Classes IPC  ?

• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• B29C 64/386 - Acquisition ou traitement de données pour la fabrication additive
• A61B 6/03 - Tomographie informatisée
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
• B29L 31/00 - Autres objets particuliers
• B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive
• B29K 67/00 - Utilisation de polyesters comme matière de moulage

Abrégé

Disclosed herein are systems, methods, and computer-readable storage devices for manufacturing patient-specific bolus for use in targeted radiotherapy treatment. Based on dose calculations without a bolus and based on three-dimensional scan data of a patient, the example system generates a model of a bolus for targeting radiotherapy treatment to a planning target volume or target region within the patient. The system can perform several iterations to generate a resulting model for the bolus. Then, the system can generate instructions for controlling a three-dimensional printer to generate the bolus that conforms to the patient's skin surface while also specifically targeting the planning target volume for the radiotherapy treatment. In this way, the amount of radiotherapy treatment administered to other tissue is reduced, while the costs, time, and human involvement in creating the bolus are significantly reduced.

Classes IPC  ?

• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• B29C 64/386 - Acquisition ou traitement de données pour la fabrication additive
• B29C 64/393 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• G01T 1/10 - Dosimètres luminescents
• G01T 1/20 - Mesure de l'intensité de radiation avec des détecteurs à scintillation