A device for obtaining retinal ERG signals from a target area of the retina, the device comprising means for obtaining an electrical response signal from the target area, the device additionally comprising at least one light source configured to provide a stimulus beam towards the target area, wherein the stimulus beam is modulated to provide a plurality of single pulses of light, where consecutive single pulses are separated by predetermined intervals of which at least a portion differ from each other and/or wherein at least a portion of the single pulses of light comprise predetermined durations of which at least a portion differ from each other.
An arrangement for providing retinal ERG stimulus and heating, the arrangement comprising at least one processor (102) and at least one light source (LEDS) for providing at least a stimulus beam to induce an ERG signal from a target area of the retina, the arrangement additionally comprising a heating system (LF) for elevating the temperature of at least the target area, wherein the processor (102) is configured to receive a retinal ERG signal induced by the stimulus beam during retinal heating, determine, based on said ERG signal, one or more indicators being indicative of a temperature of the retina, and control the heating system (LF) based on said indicator.
A device for obtaining retinal ERG signals from a target area of the retina, the device comprising means for obtaining an electrical response signal from the target area and at least one light source configured to provide at least a stimulus beam configured to illuminate the target area for inducing an ERG signal and a light adapting background beam configured to illuminate the retina at least in an area outside of the target area, for light adapting the area outside of the target area and suppressing ERG signaling therefrom.
A61B 5/398 - Électrooculographie [EOG], p. ex. pour la détection du nystagmusÉlectrorétinographie [ERG]
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
A61B 5/01 - Mesure de la température de parties du corps
4.
A DEVICE FOR OBTAINING ERG SIGNALS WITH RELATED ARRANGEMENT AND METHOD
A device for obtaining retinal ERG signals from atarget area of the retina, the device comprisingmeans for obtaining an electrical response signalfrom the target area, the device additionallycomprising at least one light source configured toprovide a stimulus beam towards the target area,wherein the stimulus beam is modulated toprovide a plurality of single pulses of light, whereconsecutive single pulses are separated bypredetermined intervals of which at least aportion differ from each other and/or wherein atleast a portion of the single pulses of lightcomprise predetermined durations of which atleast a portion differ from each other.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
5.
Method and device for determining changes in retinal and/or brain temperature
In the solution of the invention at least one an electrical response signal from a retina is acquired in a first temperature, at least one electrical response signal from the retina is acquired in at least a second temperature, the second temperature being different than the first temperature. At least the electrical response signal acquired in the second temperature is transformed with a plurality of different transformation parameter values resulting a plurality of different transformed signals. The different transformed signals of the electrical response signal in the second temperature are compared to the electrical response signal and/or the transformed signals acquired from the retina in the first temperature. The transformed electrical response signal which produces the highest similarity measure with the electrical response signal and/or transformed signal acquired from the retina in the first temperature is selected. The transformation parameter value or parameter values of the selected transformed signal is converted to a temperature, temperature difference estimate and/or temperature dependent indicator between the first temperature and the second temperature.
An arrangement for providing retinal ERG stimulus and heating, the arrangement comprising at least one processor (102) and at least one light source (LEDS) for providing at least a stimulus beam to induce an ERG signal from a target area of the retina, the arrangement additionally comprising a heating system (LF) for elevating the temperature of at least the target area, wherein the processor (102) is configured to receive a retinal ERG signal induced by the stimulus beam during retinal heating, determine, based on said ERG signal, one or more indicators being indicative of a temperature of the retina, and control the heating system (LF) based on said indicator.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 5/01 - Mesure de la température de parties du corps
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A device for obtaining retinal ERG signals from a target area of the retina, the device comprising means for obtaining an electrical response signal from the target area and at least one light source configured to provide at least a stimulus beam configured to illuminate the target area for inducing an ERG signal and a light adapting background beam configured to illuminate the retina at least in an area outside of the target area, for light adapting the area outside of the target area and suppressing ERG signaling therefrom.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/315 - Circuits d’entrée à cet effet spécialement adaptés à des utilisations particulières pour l’électrooculographie [EOG]Circuits d’entrée à cet effet spécialement adaptés à des utilisations particulières pour l’électrorétinographie [ERG]
A61B 5/398 - Électrooculographie [EOG], p. ex. pour la détection du nystagmusÉlectrorétinographie [ERG]
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
A61F 7/12 - Dispositifs pour chauffer ou refroidir les cavités internes du corps
A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux
A61B 5/01 - Mesure de la température de parties du corps
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Software; software and applications for medical apparatus
and instruments; software and applications related to
measuring and determining the temperature of eyes and brain;
temperature measuring devices and instruments; apparatus and
instruments for recording, transmitting, reproducing or
processing data. Surgical, medical and veterinary apparatus and instruments;
ophthalmological apparatus and instruments; medical
instruments incorporating lasers; medical lasers; electronic
medical devices and instruments; temperature measuring
devices and instruments for medical use; optical temperature
measuring instruments for medical purposes; devices for
measuring and determining the temperature of eyes and/or for
warming eyes for medical use; parts and fittings for all the
aforementioned goods. Scientific and technological services and research and
design relating thereto; design and development of computer
hardware and software; installation, updating and
maintenance of software; rental of computer software;
software as a service. Medical services; veterinary services; medical treatment
services; providing laser therapy for treating medical
conditions; medical care of the eyes; therapeutic treatment
of the eyes; medical evaluation and analysis services;
technical consultancy services relating to medical health;
advisory, consultation and information services related to
all the aforementioned services.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Software as a medical device (SaMD), downloadable, for controlling ophthalmic apparatus during the treatment of retinal diseases Ophthalmological apparatus and instruments for treating retinal diseases incorporating lasers and temperature measurement, namely, medical retina lasers incorporating recorded operating system software; component parts and fittings for all the aforementioned goods Scientific research in the field of treatment of retinal diseases; installation, updating and maintenance of software; software as a service featuring software for controlling ophthalmic apparatus during the treatment of retinal diseases and macular degeneration Medical services; medical treatment services for the treatment of retinal diseases; providing laser therapy for treating medical conditions; medical care of the eyes; physical therapeutic treatment of the eyes; medical evaluation of retinal diseases and analysis services for diagnosing retinal diseases; technical consultancy services relating to medical health; advisory, consultation and information services related to all the aforementioned services
10.
Device and method for non-invasive monitoring of retinal tissue temperature
A method and device for non-invasive monitoring of the temperature of the retina and the retinal pigment epithelium inside the eye, particularly during heating of the bottom of the eye, wherein alternating probing short-duration pulses of light, one at wavelength close to the absorption maximum of the photoreceptor cell type and the other at wavelength in the near-infrared region, are directed at the retinal tissue at appropriate time intervals. Photoreceptor cell electrical signals, photoresponses, are recorded using electroretinography (ERG) and the changes in retinal temperature are determined from changes in photoresponse kinetics and changes in photoreceptor sensitivity to the stimuli. The method is especially applicable at temperatures up to 45° C. for humans and for other animals.
A61B 5/01 - Mesure de la température de parties du corps
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux
G01K 13/00 - Thermomètres spécialement adaptés à des fins spécifiques
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61B 5/0496 - Electro-oculographie, p.ex. pour la détection de nystagmus
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61N 5/067 - Thérapie par radiations utilisant un rayonnement lumineux utilisant un rayonnement laser