An method according to the invention for manufacturing soft capsules using a rotary-die method comprises the following method steps: a) preparing a casting compound (11); b) pouring the casting compound (11) onto a casting drum (13) using a spreader box (12); c) converting the casting compound (11) on the casting drum (13) into a ribbon (29) by increasing the temperature of the casting compound (11); d) removing the rib-bon (29) from the casting drum (13) and feeding the ribbon (29) to a rotary-die encapsu-lation unit (44) consisting of an injection wedge (20) and two die rollers (21); e) encapsu-lating a filling (19) in the rotary-die encapsulation unit (44), thereby forming the soft cap-sules; the orientation of the macromolecules contained in the ribbon (29) being kept low in step d), so that the orientation of the macromolecules at the end of step d) is minimal.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
2.
STARCH-BASED DOSAGE FORM AND METHOD FOR THE PRODUCTION THEREOF
A casting compound for producing dosage forms using a mogul method has a swellable component in the form of swellable particles, as well as syrup, water, acid and active ingredient. The swellable particles are present in an evacuated state. The proportion of swellable particles is in the region of 5-25 wt.%, the water content is in the region of 15-27 wt.%, and the proportion of active ingredients is in the region of 0.01-30 wt.%.
B01F 23/70 - Prétraitement des matières à mélanger
B01F 27/60 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné
B01F 27/724 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné avec des hélices ou des sections d'hélices avec une seule hélice étroitement entourée d'un boîtier
B01F 27/726 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné avec des hélices ou des sections d'hélices avec deux hélices à pas opposé sur le même arbreMélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné avec des hélices ou des sections d'hélices avec deux hélices sur le même axe, entraînées dans des sens opposés ou à des vitesses différentes
B01F 27/92 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe sensiblement vertical avec des hélices ou des vis
B01F 33/70 - Mélangeurs spécialement adaptés pour travailler à une pression inférieure ou supérieure à la pression atmosphérique, p. ex. en combinaison avec un démoussant
B01F 27/50 - Mélangeurs de tuyaux, c.-à-d. mélangeurs dans lesquels les matières à mélanger circulent en continu dans des tuyaux, p. ex. mélangeurs à colonne
3.
APPARATUS FOR PRODUCING A MULTI-COMPONENT MASS, AND METHOD FOR PRODUCING A MULTI-COMPONENT MASS
The invention relates to an apparatus and to a method for producing a multi-component mass M, comprising: a first feed means 11 for supplying particles P; a first vacuum system 20, the first vacuum system 20 being designed to extract gases from between the supplied particles P; and a throat region device 70 having a conveying device 73 which is designed to produce a multi-component mass M from the metered particles P, in the evacuated state, together with at least one liquid component K.
B01F 27/50 - Mélangeurs de tuyaux, c.-à-d. mélangeurs dans lesquels les matières à mélanger circulent en continu dans des tuyaux, p. ex. mélangeurs à colonne
B01F 23/53 - Mélange de liquides avec des solides en utilisant des agitateurs entraînés
B01F 23/70 - Prétraitement des matières à mélanger
B01F 27/60 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné
B01F 27/724 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné avec des hélices ou des sections d'hélices avec une seule hélice étroitement entourée d'un boîtier
B01F 27/726 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné avec des hélices ou des sections d'hélices avec deux hélices à pas opposé sur le même arbreMélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné avec des hélices ou des sections d'hélices avec deux hélices sur le même axe, entraînées dans des sens opposés ou à des vitesses différentes
B01F 27/92 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe sensiblement vertical avec des hélices ou des vis
B01F 33/70 - Mélangeurs spécialement adaptés pour travailler à une pression inférieure ou supérieure à la pression atmosphérique, p. ex. en combinaison avec un démoussant
The method according to the invention for producing soft capsules using a rotary die method has the following steps: a) providing a casting compound (11); b) casting the casting compound (11) onto a casting drum (13) using a distribution box (12); c) converting the casting compound (11) on the casting drum (13) into a strip (29) by increasing the temperature of the casting compound (11); d) removing the strip (29) from the casting drum (13) and supplying the strip (29) to a rotary die encapsulation unit (44) consisting of a filling wedge (20) and two shaping rollers (21); and e) encapsulating a filler (19) in the rotary die encapsulation unit (44), whereby the soft capsules are formed. The orientation of the macromolecules contained in the strip (29) in step d) is kept low so that the orientation of the macromolecules at the end of step d) is present to a minimal extent.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
5.
PACKAGING MATERIAL COMPRISING A STARCH-BASED BARRIER COATING AND COATING COMPOSITION AND PROCESS FOR PRODUCING THE SAME
The invention relates to a starch-based coating composition for packaging materials, in particular for paper, paperboard or cardboard, wherein the starch has a molecular weight in the range of 800,000 to 50 000 000 g/mol, preferably in the range of 800,000 to 20 000 000 g/mol. The invention also relates to the use of the coating composition for surface-sealing of packaging materials so that the passage of mineral oil contaminants from the packaging material into the packaged material may be prevented. The invention further relates to a multi-layered packaging material produced by using the coating composition and to a method for producing the same.
D21H 19/12 - Couches sans pigments appliquées sous forme d'une solution utilisant de l'eau comme solvant unique, p. ex. en présence de composés acides ou alcalins
The invention relates to a new packaging material having a starch-based barrier coating, which packaging material is characterized in that the barrier coating comprises 30 to 90 wt% of starch after a possibly present filler component has been deducted, wherein at least 20% of the starch has an average molecular weight of at least 500,000 g/mol, preferably at least 1,000,000 g/mol, and at least 20 wt% of the starch in the barrier coating is in the form of gelatinized starch particles. A fraction of 0 to 70 wt% of plasticizer in the barrier coating and a weight per unit area in the range of 3 to 80 g/m2, especially preferably between 12 and 40 g/m2, allow for the creation of a mechanically stable barrier coating, which, for example on the inside of cardboard packagings, effectively prevents the diffusion of non-polar hydrocarbons and hydrocarbon derivatives and thus protects the packaged foods against contamination. The new packaging material is simple and economical to produce at high process speeds and has the additional advantage that the new packaging material can be recycled without limitation and meets possible legal requirements related to foods.
D21H 19/12 - Couches sans pigments appliquées sous forme d'une solution utilisant de l'eau comme solvant unique, p. ex. en présence de composés acides ou alcalins
A method for producing starch soft capsules comprises the following steps: preparing a mixture comprising starch, plasticizer and water, wherein more than 50 weight percent of the starch is present in the form of particles of granular starch; shaping the mixture to form a film in a shaping process; solidifying the mixture by increasing the temperature of the mixture during and/or after the shaping process by more than 5° C.; and shaping the film to form a soft capsule. Soft capsules produced by this method have starch particles bonded to one another. A device for performing this method comprises a shaping device to enable shaping of the starch material to form a film, and a heating device to perform a heat treatment to destructure the starch during and/or after the shaping. It comprises a rotary die device.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
C08L 3/00 - Compositions contenant de l'amidon, de l'amylose ou de l'amylopectine ou leurs dérivés ou leurs produits de dégradation
C08L 3/02 - AmidonSes produits de dégradation, p. ex. dextrine
In a dipping process for producing hard starch capsules a dip-coating mixture is used which comprises an aqueous film-forming coating mixture for hard capsule manufacture that comprises > 70% by weight, more particularly > 80% by weight of starch, based on the dry mixture after removal of the plasticizer, with more than 50% by weight of the starch in the liquid phase being present in the form of granular starch particles. Additionally present are plasticizers at 15% - 60% by weight of the dry mixture, a thickener at 0% - 10% by weight of the dry mixture, after removal of the plasticizer, and water at 15% - 70% by weight of the overall mixture. For the production of the hard capsules, a dipping bath is provided which comprises said dip-coating mixture. At least one hard capsule pin is immersed into the dipping bath, and so a coating is formed on the hard capsule pin; the at least one hard capsule pin is removed from the dipping bath; the hard capsule pin is optionally rotated by at least 180°; the coating adhering to the hard capsule pin is solidified by an increase in the temperature of this coating during and/or after immersion, more particularly by more than 5°C, to give a hard capsule; the hard capsule, comprising destructured starch particles, is dried; and, finally, the hard capsule is removed from the hard capsule pin.
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
9.
Starch foils and/or films and a method and use of a device for the production thereof
A method for producing starch films comprises the following steps: preparing a mixture comprising starch and water, wherein more than 50 weight percent of the starch is present in the form of particles of granular starch; shaping the mixture to form a film in a shaping process; solidifying the mixture by increasing the temperature of the mixture during and/or after the shaping process by more than 5° C. Films produced by this method have starch particles bonded to one another. A device for performing this method comprises a shaping device for enabling shaping of the starch material to form a film, and has a heating device for performing a heat treatment for destructuring of the starch during and/or after the shaping.
C09D 103/00 - Compositions de revêtement à base d'amidon, d'amylose ou d'amylopectine ou de leurs dérivés ou de leurs produits de dégradation
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
B29C 43/00 - Moulage par pressage, c.-à-d. en appliquant une pression externe pour faire couler la matière à moulerAppareils à cet effet
B29C 43/44 - Moyens de pressage pour la fabrication d'objets de longueur indéfinie
A method for producing starch soft capsules comprises the following steps: preparing a mixture comprising starch, plasticizer and water, wherein more than 50 weight percent of the starch is present in the form of particles of granular starch; shaping the mixture to form a film in a shaping process; solidifying the mixture by increasing the temperature of the mixture during and/or after the shaping process by more than 5° C.; and shaping the film to form a soft capsule. Soft capsules produced by this method have starch particles bonded to one another. A device for performing this method comprises a shaping device to enable shaping of the starch material to form a film, and a heating device to perform a heat treatment to destructure the starch during and/or after the shaping. It comprises a rotary die device.
A61K 47/00 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
A61J 3/07 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de capsules ou de petits conteneurs similaires à absorber par voie buccale
B29C 43/00 - Moulage par pressage, c.-à-d. en appliquant une pression externe pour faire couler la matière à moulerAppareils à cet effet
B29C 43/44 - Moyens de pressage pour la fabrication d'objets de longueur indéfinie
The present invention relates to a polymer mixture with a low viscosity, allowing processes for the processing of plastics materials to be accelerated while the final properties of the end products remain the same or are improved. The polymer mixture is mixed with the plastics materials in the manner of an additive. The invention further relates to the production of suitable polymer mixtures of this type and to the use thereof.
C08L 23/00 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères
C08L 23/02 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères non modifiées par un post-traitement chimique
C08L 23/04 - Homopolymères ou copolymères de l'éthylène
C08L 23/16 - Copolymères de l’éthylène et du propylène ou de l’éthylène, du propylène et de diène
12.
STARCH-BASED SOFT CAPSULE, AND METHOD AND APPARATUS FOR THE PRODUCTION THEREOF
A method for producing soft capsules made of starch includes the following steps: producing a mixture containing starch, softener, and water, more than 50 percent by weight of the starch being provided in the form of granular starch particles; shaping the mixture into a film in a shaping process; solidifying the mixture by increasing the temperature of the mixture by more than 5°C during and/or following the shaping process; and shaping the film into a soft capsule. Soft capsules produced according to said method have interlinked starch particles. An apparatus for carrying out said method comprises a shaping device to allow the starch material to be shaped into a film, and a heating device for performing a thermal treatment in order to destructure the starch during and/or following the shaping process. The apparatus further comprises a rotary die device.
A method for producing starch films includes the following steps: producing a mixture containing starch and water, more than 50 percent by weight of the starch being provided in the form of granular starch particles; shaping the mixture into a film in a shaping process; solidifying the mixture by increasing the temperature of the mixture by more than 5°C during and/or following the shaping process. Films produced according to said method have interlinked starch particles. An apparatus for carrying out said method comprises a shaping device to allow the starch material to be shaped into a film, and a heating device for performing a thermal treatment in order to destructure the starch during and/or following the shaping process.
A method for producing starch soft capsules comprises the following steps: preparing a mixture comprising starch, plasticizer and water, wherein more than 50 weight percent of the starch is present in the form of particles of granular starch; shaping the mixture to form a film in a shaping process; solidifying the mixture by increasing the temperature of the mixture during and/or after the shaping process by more than 5.degree.C; and shaping the film to form a soft capsule. Soft capsules produced by this method have starch particles bonded to one another. A device for performing this method comprises a shaping device to enable shaping of the starch material to form a film, and a heating device to perform a heat treatment to destructure the starch during and/or after the shaping. It comprises a rotary die device.
The invention relates to biomedical mixtures based on thermoplastic polymers that harden by cooperative crystallization of two polymers at body temperature.
In a low temperature casting process for producing confectionary articles on a Mogul unit, wherein swellable or soluble starch particles are mixed in a liquid phase and then this mixture is cast, wherein the starch particles do not swell or dissolve substantially until after casting, characterized in that, after mixing the solid phase with the liquid phase, the residence time of the casting mass is set in such a manner that the maximum tM of the residence time spectrum immediately after mixing the solid phase with the liquid phase is < 10 min and the half width tH of this residence time spectrum is < 10 min. Using this process, in particular filled starch-based gum-type confectionary articles can be produced. These comprise at least one filling and at least one sheath which is different from the filling, wherein the sheath contains at least one sugar and further particles of particulate starch. The confectionary articles preferably have a rubber-elastic texture which is very similar to that of gelatine products, without gelatine needing to be used therefor.
A23G 3/00 - SucreriesConfiseriesMassepainProduits enrobés ou fourrés
A23G 3/02 - Appareils spécialement conçus pour la fabrication ou le traitement des sucreries ou de la confiserieLeurs accessoires
A23G 3/12 - Appareils à mouler le sucre candi à l'état pâteux
A23G 3/54 - Produits composites, p. ex. en couches, enrobés, fourrés
A23G 3/42 - Sucreries, confiseries ou massepainProcédés pour leur fabrication caractérisés par la composition caractérisés par les hydrates de carbone utilisés, p. ex. des polysaccharides
The invention relates to novel polyvinyl alcohol (PVA) gels which gelate in situ and are suitable for nucleus (gel bodies of the intervertebral disks) replacement, and to a process and to an apparatus for administration thereof, to the use thereof and to a vessel which comprises an inventive PVA gel.
A61F 2/44 - Articulations pour l'épine dorsale, p. ex. vertèbres, disques intervertébraux
A61L 27/00 - Matériaux pour prothèses ou pour revêtement de prothèses
A61J 1/00 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
The invention relates to a novel Mogul procedure for manufacturing sweets, in particular starch-based gummi candies, which have a comparable texture to gelatin-based gummi candies, with at least one portion of the starch not being completely dissolved until after the pouring into the form of the confection article. In comparison to previous Mogul technology, the casting mass is poured at a comparatively low temperature, and the gelling and/or settling occurs at a comparatively high temperature.
A23G 3/42 - Sucreries, confiseries ou massepainProcédés pour leur fabrication caractérisés par la composition caractérisés par les hydrates de carbone utilisés, p. ex. des polysaccharides
A23G 3/34 - Sucreries, confiseries ou massepainProcédés pour leur fabrication
The invention relates to a low viscosity additive which allows the methods for processing plastics to be considerably accelerated while the properties of the final products remain the same or are improved. According to the invention, the polymer mixture is admixed to the plastics like an additive. The invention also relates to the production of suitable polymer mixtures of the above type and to their use.
C08L 23/02 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères non modifiées par un post-traitement chimique
The invention relates to a method for producing polymer mixtures with specific molecular weight distributions, said mixtures having low quantities of short-chain portions and a substantially improved processing behavior. According to the invention, the processing steps during or after synthesis of the main portion of the polymer mixture are used for producing the mixtures.
C08L 23/02 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères non modifiées par un post-traitement chimique
The invention relates to a novel Mogul procedure for manufacturing sweets, in particular starch-based gummi candies, which have a comparable texture to gelatin-based gummi candies, with at least one portion of the starch not being completely dissolved until after the pouring into the form of the confection article. In comparison to previous Mogul technology, the casting mass is poured at a comparatively low temperature, and the gelling and/or settling occurs at a comparatively high temperature.
A23G 3/42 - Sucreries, confiseries ou massepainProcédés pour leur fabrication caractérisés par la composition caractérisés par les hydrates de carbone utilisés, p. ex. des polysaccharides
brevets
