A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
B01D 21/00 - Séparation par sédimentation de particules solides en suspension dans des liquides
B01D 21/26 - Séparation du sédiment avec emploi de la force centrifuge
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
B04B 3/00 - Centrifugeurs à tambours rotatifs dans lesquels les particules ou les corps solides sont séparés par la force centrifuge et simultanément par tamisage ou filtration
A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
B01D 21/00 - Séparation par sédimentation de particules solides en suspension dans des liquides
B01D 21/26 - Séparation du sédiment avec emploi de la force centrifuge
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
B04B 3/00 - Centrifugeurs à tambours rotatifs dans lesquels les particules ou les corps solides sont séparés par la force centrifuge et simultanément par tamisage ou filtration
Medical devices for use in treating inflammatory and tissue
degenerative conditions using cells and cellular components;
medical devices for use in treating tissue degenerative
conditions using cell purification devices for isolation of
cells and cellular components within various types of
tissues; medical devices for use in treating damaged tissue
by using tissue processing system for healing of connective
tissue, reconstruction of injured tissue, and regeneration
of degenerated tissue; medical devices for use in treating
inflammatory and tissue degenerative conditions using
systems for isolating, processing, and converting the raw
components of the human body into medicine; medical devices
for use in treating inflammatory and degenerative conditions
affecting human bones, ligaments, muscles, and soft tissue
by using devices for implementing the medicine extracted
from the raw components of the human body.
Medical devices for use in treating tissue degenerative conditions using cell purification devices for isolation of cells and cellular components within various types of tissues; Medical devices for use in treating damaged tissue by using tissue processing system for healing of connective tissue, reconstruction of injured tissue, and regeneration of degenerated tissue; Medical devices for use in treating inflammatory and tissue degenerative conditions using systems for isolating, processing, and converting the raw components of the human body into medicine.; Medical devices for use in treating inflammatory and degenerative conditions affecting human bones, ligaments, muscles, and soft tissue by using devices for implementing the medicine extracted from the raw components of the human body.; Medical devices for use in treating inflammatory and tissue degenerative conditions using cells and cellular components
Business consulting services in the field of stem cells.; Business consulting services in the field of specialized medical services and products, namely, microfat processing system used for extracting cells from patient's own blood and converting it into medication for treatment of musculoskeletal disorders, degenerative and inflammatory conditions, dermatological conditions, reduction of pain, rejuvenation of skin, treatment of sexual dysfunctions, restoration of hair, and accelerating healing of wounds.; International business consulting services relating to specialized medical services and products, namely, microfat processing system used for extracting cells from patient's own blood and converting it into medication for treatment of musculoskeletal disorders, degenerative and inflammatory conditions, dermatological conditions, reduction of pain, rejuvenation of skin, treatment of sexual dysfunctions, restoration of hair, and accelerating healing of wounds.; International business consulting services relating to stem cells.; Operating on-line marketplaces featuring medical products used for the extraction from blood and processing of regenerative stem cells.; Promoting public awareness of specialized medical services and products, used for extraction and processing of regenerative human cells.; Promoting public awareness of medical services relating to the removal, processing of human blood.; Promoting public awareness of specialized medical services and products, namely, microfat processing system used for extracting cells from patient's own blood and converting it into medication for treatment of musculoskeletal disorders, degenerative and inflammatory conditions, dermatological conditions, reduction of pain, rejuvenation of skin, treatment of sexual dysfunctions, restoration of hair, and accelerating healing of wounds.; Promoting public awareness of medical services relating to the removal, processing of stem cells and treatment of medical conditions with the processed stem cells.; Providing purchase advisory and consulting services to consumers for the purchase of medical devices used for removal, treatment and processing of stem cells.; Providing purchase advisory and consulting services to consumers for the purchase of medical products, namely, microfat processing system used for extracting cells from patient's own blood and converting it into medication for treatment of musculoskeletal disorders, degenerative and inflammatory conditions, dermatological conditions, reduction of pain, rejuvenation of skin, treatment of sexual dysfunctions, restoration of hair, and accelerating healing of wounds.; Wholesale distributorships featuring medical products, namely, microfat processing system used for extracting cells from patient's own blood and converting it into medication for treatment of musculoskeletal disorders, degenerative and inflammatory conditions, dermatological conditions, reduction of pain, rejuvenation of skin, treatment of sexual dysfunctions, restoration of hair, and accelerating healing of wounds
Medical devices for use in treating inflammatory and tissue degenerative conditions using cells and cellular components; Medical devices for use in treating tissue degenerative conditions using cell purification devices for isolation of cells and cellular components within various types of tissues; Medical devices for use in treating damaged tissue by using tissue processing system for healing of connective tissue, reconstruction of injured tissue, and regeneration of degenerated tissue; Medical devices for use in treating inflammatory and tissue degenerative conditions using systems for isolating, processing, and converting the raw components of the human body into medicine; Medical devices for use in treating inflammatory and degenerative conditions affecting human bones, ligaments, muscles, and soft tissue by using devices for implementing the medicine extracted from the raw components of the human body
8.
Encapsulated adipose-derived stem cells, methods for preparation and theraputic use
A therapeutic composition comprising a purified fraction of adipose-derived mesenchymal stem cells encapsulated in a three-dimensional biocompatible gel matrix, and methods, and systems for preparing and using encapsulated adipose-derived mesenchymal stem cells. Hydrogel microbeads encapsulating stem cells maintain the viability and location of the stem cells for an extended period as compared to stem cells in suspension. The gel matrix allows the release of cellular factors from the encapsulated stem cells to surrounding tissues to achieve desired therapeutic results.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
Medical devices for use in treating inflammatory and tissue degenerative conditions using cells and cellular components; Tissue processing medical devices, namely, medical devices used for the collection and processing of various types of tissue for treating inflammatory and tissue degenerative conditions, reconstruction, regeneration and healing of connective tissues; Cell purification devices for medical applications, namely, medical devices used for the isolation of cells and cellular components within various types of tissue
10.
SYSTEM AND METHODS FOR PREPARATION OF ADIPOSE-DERIVED STEM CELLS
A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes art internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.
A61M 1/00 - Dispositifs de succion ou de pompage à usage médicalDispositifs pour retirer, traiter ou transporter les liquides du corpsSystèmes de drainage
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61M 5/34 - Structures pour le raccordement de l'aiguille
B04B 3/00 - Centrifugeurs à tambours rotatifs dans lesquels les particules ou les corps solides sont séparés par la force centrifuge et simultanément par tamisage ou filtration
B04B 5/04 - Appareils à chambre radiale pour séparer des mélanges essentiellement liquides, p. ex. butyromètres
11.
System and methods for preparation of adipose-derived stem cells
A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
B04B 3/00 - Centrifugeurs à tambours rotatifs dans lesquels les particules ou les corps solides sont séparés par la force centrifuge et simultanément par tamisage ou filtration
B01D 21/00 - Séparation par sédimentation de particules solides en suspension dans des liquides
B01D 21/26 - Séparation du sédiment avec emploi de la force centrifuge
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
12.
System and methods for preparation of adipose-derived stem cells
A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.
A61M 1/00 - Dispositifs de succion ou de pompage à usage médicalDispositifs pour retirer, traiter ou transporter les liquides du corpsSystèmes de drainage
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61M 5/34 - Structures pour le raccordement de l'aiguille
B04B 5/04 - Appareils à chambre radiale pour séparer des mélanges essentiellement liquides, p. ex. butyromètres
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
B01D 21/26 - Séparation du sédiment avec emploi de la force centrifuge
B04B 3/00 - Centrifugeurs à tambours rotatifs dans lesquels les particules ou les corps solides sont séparés par la force centrifuge et simultanément par tamisage ou filtration
13.
Encapsulated adipose-derived stem cells, methods for preparation and therapeutic use
A therapeutic composition comprising a purified fraction of adipose-derived mesenchymal stem cells encapsulated in a three-dimensional biocompatible gel matrix, and methods, and systems for preparing and using encapsulated adipose-derived mesenchymal stem cells. Hydrogel microbeads encapsulating stem cells maintain the viability and location of the stem cells for an extended period as compared to stem cells in suspension. The gel matrix allows the release of cellular factors from the encapsulated stem cells to surrounding tissues to achieve desired therapeutic results.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
A system for extracting and processing adipose tissue to generate a therapeutically effective amount of adipose-derived stem cells, comprising an adipose tissue extraction device and a modified centrifuge tube comprising a plurality of lipoaspirate inlet fittings, a plurality of processing fluid inlet fittings, and a plurality of pellet extraction tubes. The adipose tissue extraction device is used to extract a quantity of adipose tissue from a human being, the lipoaspirate is moved into the first modified centrifuge tube via a sterile transfer, a plurality of processing steps are performed to clean and dissociate the lipoaspirate, and a pellet containing an enhanced fraction of stem cells is obtained by centrifuging the modified centrifugal tube. The pellet is resuspended in a fluid and administered to a human patient for a therapeutic or cosmetic purpose.
A system for extracting and processing adipose tissue to generate a therapeutically effective amount of adipose-derived stem cells, comprising an adipose tissue extraction device and a modified centrifuge tube comprising a plurality of lipoaspirate inlet fittings, a plurality of processing fluid inlet fittings, and a plurality of pellet extraction tubes. The adipose tissue extraction device is used to extract a quantity of adipose tissue from a human being, the lipoaspirate is moved into the first modified centrifuge tube via a sterile transfer, a plurality of processing steps are performed to clean and dissociate the lipoaspirate, and a pellet containing an enhanced fraction of stem cells is obtained by centrifuging the modified centrifugal tube. The pellet is resuspended in a fluid and administered to a human patient for a therapeutic or cosmetic purpose.
A61M 1/00 - Dispositifs de succion ou de pompage à usage médicalDispositifs pour retirer, traiter ou transporter les liquides du corpsSystèmes de drainage
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A therapeutic composition comprising a purified fraction of adipose-derived mesenchymal stem cells encapsulated in a three-dimensional biocompatible gel matrix, and methods, and systems for preparing and using encapsulated adipose-derived mesenchymal stem cells. Hydrogel microbeads encapsulating stem cells maintain the viability and location of the stem cells for an extended period as compared to stem cells in suspension. The gel matrix allows the release of cellular factors from the encapsulated stem cells to surrounding tissues to achieve desired therapeutic results.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61P 19/08 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
