Embodiments generally describe systems, devices, and methods for focusing and calibrating beam profilers. A test object is provided that may include an internal housing rotatable within an external housing. The internal housing may house a light source, a collimator, a filter, and/or a diffuser. A plate may be mounted to the internal housing and may include a plurality of markings. In some embodiments, to focus a beam profiler, the test object may be positioned adjacent the converter plate of a beam profiler. Marker images may be captured and a focus quality may be assessed therefrom. A position of the converter, objective, and/or camera of the beam profiler may be adjusted based on the focus quality. To calibrate, images of the markings in several rotational positions may be captured and used for calibration. The markings may be rotated to several positions by rotating the internal housing relative to the external housing.
Ophthalmological surgery systems comprised of a laser source and optics to deliver laser energy to the eye, parts therefor, and computer software and instructional manuals, data sheets and product folders, sold together as a unit
3.
Presbyopia correction through negative spherical aberration
Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in one or both of a patient's eyes, often as a controlled amount of negative spherical aberration extending across a pupil. A desired presbyopia-mitigating quantity of high-order spherical aberration may be defined by one or more spherical Zernike coefficients, which may be combined with Zernike coefficients generated from a wavefront aberrometer. The resulting prescription can be imposed using refractive surgical techniques such as laser eye surgery, using intraocular lenses and other implanted structures, using contact lenses, using temporary or permanent corneal reshaping techniques, and/or the like.
A61B 3/103 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p.ex. réfractomètres, skiascopes
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
Embodiments of the present invention generally describe systems, devices, and methods for directly measuring pulse profiles during pulse delivery. In some embodiment, the pulse profiles may be measured while the pulse is delivered to ablate a material. Embodiments, may calculate ablation spot parameters based on the pulse profiles and may refine one or more subsequent laser pulses based on deviations from the calculated ablation spot parameters from desired ablation spot parameters. In some embodiments, a fluence profiler is provided. The fluence profiler may measure a pulse profile of a laser pulse from a portion of the laser pulse. The fluence profiler may utilize a UV radiation energy sensor device and a camera-based imager. The measurements from the UV radiation energy sensor device and the camera-based imager may be combined and scaled to provide a measured pulse profile that corresponds to the delivered pulse.
Embodiments of the present invention generally describe systems, devices, and methods for directly measuring pulse profiles during pulse delivery. In some embodiment, the pulse profiles may be measured while the pulse is delivered to ablate a material. Embodiments, may calculate ablation spot parameters based on the pulse profiles and may refine one or more subsequent laser pulses based on deviations from the calculated ablation spot parameters from desired ablation spot parameters. In some embodiments, a fluence profiler is provided. The fluence profiler may measure a pulse profile of a laser pulse from a portion of the laser pulse. The fluence profiler may utilize a UV radiation energy sensor device and a camera-based imager. The measurements from the UV radiation energy sensor device and the camera-based imager may be combined and scaled to provide a measured pulse profile that corresponds to the delivered pulse.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
G01J 11/00 - Mesure des caractéristiques d'impulsions lumineuses individuelles ou de trains d'impulsions lumineuses
G01J 1/42 - Photométrie, p.ex. posemètres photographiques en utilisant des détecteurs électriques de radiations
G01J 1/10 - Photométrie, p.ex. posemètres photographiques par comparaison avec une lumière de référence ou avec une valeur électrique de référence
G01J 1/58 - Photométrie, p.ex. posemètres photographiques en utilisant une luminescence produite par la lumière
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes en utilisant des lasers
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Medical services; treatment of eye diseases and conditions; ophthalmic surgery; lasik and other surgical procedures to correct and improve vision; providing an internet website in the field of medicine for medical professionals and medical patients featuring information on ophthalmic medical devices, diagnosis and treatments.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Medical services, namely, treatment of eye diseases and conditions; ophthalmic surgery; lasik and other surgical procedures to correct and improve vision; providing an internet website for medical professionals and medical patients featuring information on ophthalmic medical devices, diagnosis and treatments.
8.
SYSTEMS AND METHODS FOR CORRECTING HIGH ORDER ABERRATIONS IN LASER REFRACTIVE SURGERY
Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.
Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Medical devices, namely, ophthalmological laser refractive surgery systems comprised primarily of a laser source, a sensing device and optics for refractive diagnosis and laser ablation of the eye, and parts and software therefor
11.
Optical surface shape determination by mapping a lenslet array spot pattern to a spatial frequency space
Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.
G01J 1/20 - Photométrie, p.ex. posemètres photographiques par comparaison avec une lumière de référence ou avec une valeur électrique de référence l'intensité de la valeur mesurée ou de référence étant modifiée jusqu' à égalisation de leurs effets au niveau du détecteur, p.ex. en faisant varier l'angle d'incidence
The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.
Methods, devices, and systems for predicting an optical acuity measure of an optical system of an eye. An optical acuity measure can be predicted by determining a point spread function based on a wavefront measurement of an eye, convolving a resolution target with the point spread function to produce an image, and predicting the optical acuity measure of the optical system of the eye based on the image.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
14.
Calibrating laser beam position and shape using an image capture device
The present invention provides improved methods and systems for laser beam positioning, shape profile, size profile, drift, and/or deflection calibration using an image capture device, such as a microscope camera, for enhanced calibration accuracy and precision. The methods and systems are particularly suited for iris calibration and hysteresis measurement of a variable diameter aperture. One method for calibrating laser pulses from a laser eye surgery system using an image capture device comprises imaging a known object with an image capture device. A pulsed laser beam is directed onto a calibration surface so as to leave a mark on the calibration surface. The mark on the calibration surface is then imaged with the image capture device. The laser eye surgery system is calibrated by comparing the image of the mark on the calibration surface to the image of the known object.
Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.
A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes en utilisant des lasers
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
16.
Non-invasive measurement of tear volume systems and methods
Devices systems, and methods can measure, diagnose and/or characterize an eye of a patient, including physiologic and optical properties, such as hydration and tear volume in relation to an optical surface of the eye, including topography of a corneal surface of the eye and/or a wavefront elevation map of the eye. The system forms an image of a tear meniscus along an eyelid. The eye can be illuminated so that the meniscus appears as a dark band in the image. Tear volume can be determined by measuring a height across the tear meniscus. The tear volume can be used to determine the optical properties of the tear of the eye and to diagnose conditions of the eye. The patient can be screened for treatment of the eye with refractive surgery using a measured pupil size, hydration and topography and/or wavefront.
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
17.
Methods and systems for tracking a torsional orientation and position of an eye
Methods and systems for tracking a position and torsional orientation of a patient's eye. In one embodiment, the present invention provides methods and software for registering a first image of an eye with a second image of an eye. In another embodiment, the present invention provides methods and software for tracking a torsional movement of the eye. In a particular usage, the present invention tracks the torsional cyclorotation and translational movement of a patient's eye so as to improve the delivery of a laser energy to the patient's cornea.
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/113 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
18.
Pupilometer for pupil center drift and pupil size measurements at differing viewing distances
The present invention generally provides improved devices, systems, and methods for measuring characteristics of at least one eye, and particularly for measuring the physiological changes in eyes under different viewing conditions. An exemplary embodiment provides a pupilometer which measures any changes in location of a pupil center with changes in viewing distances. As the eye often moves significantly during viewing, the pupil center location will often be measured relative to a convenient reference of the eye such as an outer iris boundary. Pupil size may also be recorded, and the measurements from both eyes of a patient may be taken simultaneously. Exemplary embodiments may be configured so as to allow the vergence angle between the eyes to vary with differing viewing distances, regardless of whether one or both eyes are being measured.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
19.
Operator-controlled scanning laser procedure designed for large-area epithelium removal
Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such penetration of the epithelial layer can be detected.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes en utilisant des lasers
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets
20.
COMBINED WAVEFRONT AND TOPOGRAPHY SYSTEMS AND METHODS
Methods, software, and systems are provided for determining an ablation target shape for a treatment for an eye of a patient. Techniques include determining wavefront information from the eye of the patient with a wavefront eye refractometer, determining anterior corneal shape information from the eye with a corneal topography device, and combining the wavefront information and the anterior corneal shape information to determine the ablation target shape.
A61B 3/103 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p.ex. réfractomètres, skiascopes
A61B 3/107 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
21.
Transformation methods of wavefront maps from one vertex distance to another
The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
22.
Calculating Zernike coefficients from Fourier coefficients
Systems, methods, and devices for determining an optical surface model for an optical tissue system of an eye are provided. Techniques include inputting a Fourier transform of optical data from the optical tissue system, inputting a conjugate Fourier transform of a basis function surface, determining a Fourier domain sum of the Fourier transform and the conjugate Fourier transform, calculating an estimated basis function coefficient based on the Fourier domain sum, and determining the optical surface model based on the estimated basis function coefficient. The approach is well suited for employing Fourier transform in wavefront reconstruction using Zernike representation.
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
23.
Operator-controlled scanning laser procedure designed for large-area epithelium removal
Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such that an operator can detect penetration of the epithelial layer.
A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes en utilisant des lasers
24.
OPERATOR-CONTROLLED SCANNING LASER PROCEDURE DESIGNED FOR LARGE-AREA EPITHELIUM REMOVAL
Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such that an operator can detect penetration of the epithelial layer.
A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes en utilisant des lasers
The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
26.
Systems and methods for wavefront analysis over circular and noncircular pupils
Systems, methods, and software for determining a set of analytical or numerical polynomials that is orthonormal over circular or noncircular pupils are described. Closed-form orthonormal polynomials for circular, annular, hexagonal, elliptical, rectangular, and square pupils are derived. Such techniques can be applied to ray tracing as in the optical design and wavefront fitting from measurement as in the optical testing. These approaches can also be applied to wavefront reconstruction in adaptive optics.
G06F 7/60 - Méthodes ou dispositions pour effectuer des calculs en utilisant une représentation numérique non codée, c. à d. une représentation de nombres sans base; Dispositifs de calcul utilisant une combinaison de représentations de nombres codées et non codées
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
27.
Spatial frequency wavefront sensor system and method
Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.
G01J 1/20 - Photométrie, p.ex. posemètres photographiques par comparaison avec une lumière de référence ou avec une valeur électrique de référence l'intensité de la valeur mesurée ou de référence étant modifiée jusqu' à égalisation de leurs effets au niveau du détecteur, p.ex. en faisant varier l'angle d'incidence
G06K 9/36 - Prétraitement de l'image, c. à d. traitement de l'information image sans se préoccuper de l'identité de l'image
28.
LASER ENERGY CALIBRATION BASED ON OPTICAL MEASUREMENT
Systems and method for determining ablation beam characteristics are provided. Methods include ablating an article with the ablation beam to form a test location having an ablation depth, transmitting a first beam through the test location of the article, transmitting a second beam through a reference location, and determining an ablation beam characteristic based on a phase relationship of the first beam and the second beam downstream of the article. Systems include a light source assembly transmitting a first beam through an ablated test location of an article and a second beam through a reference location disposed outside of the test location, a sensor assembly detecting a first beam and second beam superimposition downstream of the article, and a phase relationship code module for determining a phase relationship between the first beam and the second beam, based on the first beam and second beam superimposition.
Devices, systems, and methods control pulse energies of excimer and other lasers, particularly for refractive correction in which a pulse rate, pulse energy, or other parameters of a pulsed laser is varied during use. A calibration laser mode may be used to fire a series of laser pulses to characterize a correlation between laser energy and a laser operation parameter (typically discharge high voltage) throughout a range. During an operation mode, subsequent voltages may be set based on energies of prior pulses while accounting for a curve or change in rate of the correlation.
H01S 3/104 - Commande de l'intensité, de la fréquence, de la phase, de la polarisation ou de la direction du rayonnement, p.ex. commutation, ouverture de porte, modulation ou démodulation par commande du milieu actif, p.ex. par commande des procédés ou des appareils pour l'excitation dans des lasers à gaz
H01S 3/225 - Lasers, c. à d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet caractérisés par le matériau utilisé comme milieu actif à gaz le gaz actif étant polyatomique, c. à d. contenant plusieurs atomes comprenant un excimer ou un exciplex
30.
SYSTEMS AND METHODS FOR WAVEFRONT ANALYSIS OVER CIRCULAR AND NONCIRCULAR PUPILS
Systems, methods, and software for determining a set of analytical or numerical polynomials that is orthonormal over circular or noncircular pupils are described. Closed-form orthonormal polynomials for circular, annular, hexagonal, elliptical, rectangular, and square pupils are derived. Such techniques can be applied to ray tracing as in the optical design and wavefront fitting from measurement as in the optical testing. These approaches can also be applied to wavefront reconstruction in adaptive optics.
A61B 3/103 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p.ex. réfractomètres, skiascopes
31.
COMPRESSION HEAD PILLOW AND NECK ANGLE ADJUSTMENT MECHANISM FOR REFRACTIVE LASER SURGERY AND THE LIKE
Improved devices, systems, and methods support and/or restrain a head of a patient, optionally for use in refractive surgery. Both the height of the patient's head and the angle of the patient's neck along the medial-lateral plane of the patient can be established independently, and compression pillow systems can gently and atraumatically compress the patient's head between protruding foam sidewalls or the like to inhibit movement of the patient from the alignment position.
Devices, systems, and methods often by measuring characterize optical structures and systems, the standard refractive error and irregular aberrations. A retinal spot can propagate through optical tissues of an eye and can be directed to refractive correction optics for correcting standard refractive errors. The corrected image is then directed to wavefront analysis optics, which form a coarse pitch lenslet array pattern and a fine pitch lenslet array pattern. The coarse pitch pattern indicates the standard refractive error of the eye, and can be used to adjust the refractive correction optics. The fine pitch pattern is formed with the corrected retinal image, facilitating precise wavefront reconstruction, measurement of high order aberrations, and the like. The coarse pitch pattern and fine pitch pattern may be formed sequentially or simultaneously.
A61B 3/103 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p.ex. réfractomètres, skiascopes
33.
Systems and methods for wavefront reconstruction for aperture with arbitrary shape
Systems, methods, and devices for determining an aberration in an optical tissue system of an eye are provided. Techniques include inputting optical data from the optical tissue system of the eye, where the optical data includes set of local gradients corresponding to a non-circular shaped aperture, processing the optical data with an iterative Fourier transform to obtain a set of Fourier coefficients, converting the set of Fourier coefficients to a set of modified Zernike coefficients that are orthogonal over the non-circular shaped aperture, and determining the aberration in the optical tissue system of the eye based on the set of modified Zernike coefficients.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
34.
SYSTEMS AND METHODS FOR WAVEFRONT RECONSTRUCTION FOR APERTURE WITH ARBITRARY SHAPE
Systems, methods, and devices for determining an aberration in an optical tissue system of an eye are provided. Techniques include inputting optical data from the optical tissue system of the eye, where the optical data includes set of local gradients corresponding to a non-circular shaped aperture, processing the optical data with an iterative Fourier transform to obtain a set of Fourier coefficients, converting the set of Fourier coefficients to a set of modified Zernike coefficients that are orthogonal over the non-circular shaped aperture, and determining the aberration in the optical tissue system of the eye based on the set of modified Zernike coefficients.
A61B 3/107 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
A61B 3/103 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p.ex. réfractomètres, skiascopes
Devices, systems, and methods for laser eye surgery selectively ablate tissues within the cornea of an eye along one or more target surfaces, so that corneal tissue bordered by the laser incision surface(s) can be mechanically removed. An appropriate tissue-shaping surface can be selected based on the regular refractive error of the eye, and a shape of the target laser surface(s) can be calculated so as to correct irregular refractive errors of the eye, impose desired additional sphero-cylindrical and/or irregular alterations.
Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
Devices, systems, and methods for supporting and/or stabilizing a patient can help to position a patient relative to a therapeutic laser beam, for example, inhibiting motion or deflection during a refractive procedure on the eyes, and the like. A stabilizing structural member can support a chair or other patient support near shoulders of the patient, and the member may remain stationary while the chair is driven in a horizontal plane by a linkage. Often, a nominal patient center of gravity is located between the support member and a portion of the patient support which is supported by the linkage to reduce cantilever effects. The member may be rigidly attached to a vertical motion stage which moves the chair at an angle, for example at an angle normal to the horizontal plane.
A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)
The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
Devices, systems, and methods control pulse energies of excimer and other lasers, particularly for refractive correction in which a pulse rate, pulse energy, or other parameters of a pulsed laser is varied during use. A calibration laser mode may be used to fire a series of laser pulses to characterize a correlation between laser energy and a laser operation parameter (typically discharge high voltage) throughout a range. During an operation mode, subsequent voltages may be set based on energies of prior pulses while accounting for a curve or change in rate of the correlation.
Devices systems, and methods can measure, diagnose and/or characterize an eye of a patient, including physiologic and optical properties, such as hydration and tear volume in relation to an optical surface of the eye, including topography of a corneal surface of the eye and/or a wavefront elevation map of the eye. The system forms an image of a tear meniscus along an eyelid. The eye can be illuminated so that the meniscus appears as a dark band in the image. Tear volume can be determined by measuring a height across the tear meniscus. The tear volume can be used to determine the optical properties of the tear of the eye and to diagnose conditions of the eye. The patient can be screened for treatment of the eye with refractive surgery using a measured pupil size, hydration and topography and/or wavefront.
Devices, systems, and methods for supporting and/or stabilizing a patient can help to position a patient relative to a therapeutic laser beam, for example, inhibiting motion or deflection during a refractive procedure on the eyes, and the like. A stabilizing structural member can support a chair or other patient support near shoulders of the patient, and the member may remain stationary while the chair is driven in a horizontal plane by a linkage. Often, a nominal patient center of gravity is located between the support member and a portion of the patient support which is supported by the linkage to reduce cantilever effects. The member may be rigidly attached to a vertical motion stage which moves the chair at an angle, for example at an angle normal to the horizontal plane.
A47B 13/00 - TABLES; BUREAUX; MOBILIER DE BUREAU; MEUBLES À TIROIRS; TIROIRS; PARTIES CONSTITUTIVES GÉNÉRALES DES MEUBLES - Parties constitutives des tables ou des bureaux
42.
SYSTEMS AND METHODS FOR QUALIFYING AND CALIBRATING A BEAM DELIVERY SYSTEM
Systems and methods for testing a laser eye surgery system are provided. Methods include establishing an image scale based on a calibration pattern, imageably altering a series of regions of a test surface with the laser system, laterally redirecting a laser beam to form a test pattern, imaging the test pattern, determining a lateral redirecting characteristic of the beam delivery system, and qualifying or calibrating the beam delivery system. Systems can include an input module that accepts an input member such as a calibration pattern parameter, a calibration pattern image, an intended pattern parameter, a test pattern image, an imaging device position, a calibration pattern position, a test pattern position, and a beam delivery system position, a characterization module that determines a beam delivery system characteristic, and an output module that generates a calibration for the beam delivery system of the laser eye surgery system.
Systems and method for determining ablation beam characteristics are provided. Methods include ablating an article with the ablation beam to form a test location having an ablation depth, transmitting a first beam through the test location of the article, transmitting a second beam through a reference location, and determining an ablation beam characteristic based on a phase relationship of the first beam and the second beam downstream of the article. Systems include a light source assembly transmitting a first beam through an ablated test location of an article and a second beam through a reference location disposed outside of the test location, a sensor assembly detecting a first beam and second beam superimposition downstream of the article, and a phase relationship code module for determining a phase relationship between the first beam and the second beam, based on the first beam and second beam superimposition.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes
44.
Systems and methods for qualifying and calibrating a beam delivery system
Systems and methods for testing a laser eye surgery system are provided. Methods include establishing an image scale based on a calibration pattern, imageably altering a series of regions of a test surface with the laser system, laterally redirecting a laser beam to form a test pattern, imaging the test pattern, determining a lateral redirecting characteristic of the beam delivery system, and qualifying or calibrating the beam delivery system. Systems can include an input module that accepts an input member such as a calibration pattern parameter, a calibration pattern image, an intended pattern parameter, a test pattern image, an imaging device position, a calibration pattern position, a test pattern position, and a beam delivery system position, a characterization module that determines a beam delivery system characteristic, and an output module that generates a calibration for the beam delivery system of the laser eye surgery system.
Systems, methods, and devices for determining an optical surface model for an optical tissue system of an eye are provided. Techniques include inputting a Fourier transform of optical data from the optical tissue system, inputting a conjugate Fourier transform of a basis function surface, determining a Fourier domain sum of the Fourier transform and the conjugate Fourier transform, calculating an estimated basis function coefficient based on the Fourier domain sum, and determining the optical surface model based on the estimated basis function coefficient. The approach is well suited for employing Fourier transform in wavefront reconstruction using Zernike representation.
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/103 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p.ex. réfractomètres, skiascopes
46.
CALCULATING ZERNIKE COEFFICIENTS FROM FOURIER COEFFICIENTS
Systems, methods, and devices for determining an optical surface model for an optical tissue system of an eye are provided. Techniques include inputting a Fourier transform of optical data from the optical tissue system, inputting a conjugate Fourier transform of a basis function surface, determining a Fourier domain sum of the Fourier transform and the conjugate Fourier transform, calculating an estimated basis function coefficient based on the Fourier domain sum, and determining the optical surface model based on the estimated basis function coefficient. The approach is well suited for employing Fourier transform in wavefront reconstruction using Zernike representation.
A61B 3/107 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
47.
Presbyopia correction through negative high-order spherical aberration
Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in one or both of a patient's eyes, often as a controlled amount of negative spherical aberration extending across a pupil. A desired presbyopia-mitigating quantity of high-order spherical aberration may be defined by one or more spherical Zernike coefficients, which may be combined with Zernike coefficients generated from a wavefront aberrometer. The resulting prescription can be imposed using refractive surgical techniques such as laser eye surgery, using intraocular lenses and other implanted structures, using contact lenses, using temporary or permanent corneal reshaping techniques, and/or the like.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes
48.
Database system for centralized clinical and research applications with data from wavefront aberrometers
Computer systems, programs, and methods can advantageously be used to process optical data. These approaches often involve modifying a first format data to a second format data, and are useful in simplifying the complications due to data from different wavefront systems, different aberrometer devices and aberrometer software versions, different clinical studies and different measurement conditions. A centralized database system can be used effectively in a clinical research setting, which can be a medical center, a college, or a research department in a company, or in other diagnosis or treatment facilities.
Surgical and medical apparatus and instruments; medical devices, namely, ophthalmological surgery systems comprised primarily of a laser source, a sensing device and optics for refractive diagnosis and laser ablation of the eye and parts and software therefore, sold together as a unit.
50.
Calibrating laser beam position and shape using an image capture device
The present invention provides improved methods and systems for laser beam positioning, shape profile, size profile, drift, and/or deflection calibration using an image capture device, such as a microscope camera, for enhanced calibration accuracy and precision. The methods and systems are particularly suited for iris calibration and hysteresis measurement of a variable diameter aperture. One method for calibrating laser pulses from a laser eye surgery system using an image capture device comprises imaging a known object with an image capture device. A pulsed laser beam is directed onto a calibration surface so as to leave a mark on the calibration surface. The mark on the calibration surface is then imaged with the image capture device. The laser eye surgery system is calibrated by comparing the image of the mark on the calibration surface to the image of the known object.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c. à d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
G01B 11/00 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques
Systems and methods provide for stabilizing the amount of laser energy delivered to a target from a laser device. Generally, delivered laser energy is measured over multiple laser pulses or over time in the case of a constant wave laser. A decrease is then calculated in the delivered energy, the decrease being caused by accumulation of one or more substances, such as ozone, along the laser beam delivery path due to passage of the laser beam along the path. Using this calculated decrease, a laser device may be adjusted to compensate for the decrease in delivered energy due to the accumulated substance(s), thus stabilizing the amount of energy delivered to the target.
A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)
A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes en utilisant des lasers
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
16 - Papier, carton et produits en ces matières
Produits et services
Software relating to medical devices, including ophthalmological surgery systems comprised primarily of a laser source, a sensing device and optics for refractive diagnosis and laser ablation of the eye. Medical devices, namely, ophthalmological surgery systems comprised primarily of a laser source, a sensing device and optics for refractive diagnosis and laser ablation of the eye, and parts and accessories therefore; namely non-articulating and articulating chairs, head cradle pillows, knee pillows, knob kit consisting of encoder caps, joystick cap and flat pillows with vacuum pillows, microscope cap, sterile trays, sterile console drapes, sterile slit illuminator sleeves, USB drives, wrench for gas bottles, scan converters, printers and cables, access port for printers, built-in slit illuminators, spare slit illuminators, modem. Instructional manuals, data sheets for medical devices.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
16 - Papier, carton et produits en ces matières
Produits et services
Software relating to medical devices, including ophthalmological surgery systems comprised primarily of a laser source, a sensing device and optics for refractive diagnosis and laser ablation of the eye; medical hardware devices, namely USB drives and modems. Medical devices, namely, ophthalmological surgery systems comprised primarily of a laser source, a sensing device and optics for refractive diagnosis and laser ablation of the eye, and parts, data sheets,and accessories therefor, namely non-articulating and articulating chairs, head cradle pillows, knee pillows, knob kit consisting of encoder caps, joystick cap and flat pillows with vacuum pillows, microscope cap, sterile trays, sterile console drapes, sterile slit illuminator sleeves, wrench for gas bottles, scan converters, printers and cables, access port for printers, built-in slit illuminators, spare slit illuminators. Instructional manuals, data sheets for medical devices( printed).
54.
Systems and methods for correcting high order aberrations in laser refractive surgery
Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.
A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)
A method for determining a refractive correction for an eye involves measuring an optical error of the eye, calculating at least one image quality parameter for a selected spatial frequency of range of spatial frequencies, based on the measured optical error of the eye, and forming a plan for refractive correction of the optical error, based on the calculated image quality parometer. In some embodiments, measuring the optical error involves taking one or more wavefront measurements. In some embodiments, calculating the parameter involves calculation a modulation transfer function.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
16 - Papier, carton et produits en ces matières
Produits et services
(1) Computer software as part of ophthalmological surgery systems sold together as a unit with a laser source and optics to deliver laser energy to the eye, parts therefor, and instructional manuals, data sheets and product folders.
(2) Laser source and optics to deliver laser energy to the eye and parts therefor as part of ophthalmological surgery systems sold together as a unit with computer software and instructional manuals, data sheets and product folders.
(3) Instructional manual, data sheets and product folders as part of ophthalmological surgery systems sold together as a unit with a laser source and optics to deliver laser energy to the eye, parts therefor, and computer software.
Ophthalmological laser refractive surgery systems comprised of a laser source and optics to deliver laser energy to the eye, and parts and software therefore. Instruction manuals, datasheets and product folders for ophthalmological laser refractive surgery systems.
(1) Ophthalmological laser refractive surgery systems comprised of a laser source and optics to deliver laser energy to the eye, parts and software therefore, and instruction manuals and data sheets and product folders sold together as a unit.
Ophthalmological laser refractive surgery systems comprised of a laser source and optics to deliver laser energy to the eye, and parts and software therefore. Instruction manuals, datasheets and product folders for ophthalmological laser refractive surgery systems.
61.
Application of blend zones, depth reduction, and transition zones to ablation shapes
Methods, devices, and systems for reprofiling a surface of a cornea of an eye ablate a portion of the cornea to create an ablation zone with an optically correct central optical zone disposed in a central portion of the cornea, and a blend zone disposed peripherally to the central optical zone and at least partially within an optical zone of the eye. The blend zone can have an optical power that gradually diminishes with increasing radius from the central optical zone.
A method for measuring an optical system comprises transmitting an image with the optical system. Gradients of the optical system can be determined by separating the transmitted image with a lenslet array. An error-correcting change in the shape of the optical system can be mapped by integrating across the gradients. The change in elevation around the path is related to the accuracy of the gradient array. A system for measuring a wavefront of an eye includes an image source for projecting an image into the eye, lenslets, a detector for measuring angles of light rays of an optical surface of an eye, and a computer for mapping the errors of the eye. A tomographic wavefront map is made by deflecting the measurement path of the wavefront sensor. Aberrations are selected for treatment in response to an order of the aberration and a tissue structure corresponding to the aberration.
(1) Medical devices, namely, a laser refractive surgical system consisting primarily of a laser source, a sensing device and optics for creating a map of the topography of the eye for refractive diagnosis and laser ablation of the eye, and parts and software therefor.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Software for medical devices, namely, a laser refractive surgical system consisting primarily of a laser source, a sensing device and optics for creating a map of the topography of the eye for refractive diagnosis and laser ablation of the eye, and parts therefor.
(2) Medical devices, namely, a laser refractive surgical system consisting primarily of a laser source, a sensing device and optics for creating a map of the topography of the eye for refractive diagnosis and laser ablation of the eye, and parts therefor.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Medical devices, namely ophthalmological laser refractive surgical systems consisting primarily of a laser source, a sensing device and optics for creating a map of the topography of the eye for refractive diagnosis and laser ablation of the eye, and parts and software therefor.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Medical devices, namely a laser refractive surgical system consisting primarily of a laser source, a sensing device and optics for creating a map of the topography of the eye for refractive diagnosis and laser ablation of the eye, and parts and software therefor.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Medical devices, namely a laser refractive surgical system consisting primarily of a laser source, a sensing device and optics for creating a map of the topography of the eye for refractive diagnosis and laser ablation of the eye, and parts and software therefor.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Ophthalmological surgery systems comprised of a laser source and optics, namely lenses, mirrors, prisms, scanning mechanisms, beam shaping devices to deliver laser energy to the eye, and parts and software therefor.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Ophthalmological surgery systems comprised of a laser source and optics, namely lenses, mirrors, prisms, scanning mechanisms, beam shaping devices, to deliver laser energy to the eye, and parts and software therefor.
09 - Appareils et instruments scientifiques et électriques
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
(1) Laser systems for use in ophthalmological surgery and components thereof, namely mirrors, lasers, beam integration modules, beam shaping modules and hyperopia modules, and software for all of the foregoing. (1) Education and training in the use and operation of ophthalmolgical surgery systems.
09 - Appareils et instruments scientifiques et électriques
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
(1) Laser systems for use in ophthalmological surgery and components thereof, namely mirrors, lasers, beam integration modules, beam shaping modules and hyperopia modules, and software for all of the foregoing. (1) Education and training in the use and operation of ophthalmological surgery systems.
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Ophthalmological surgical apparatus and instruments; parts and fittings therefor. Educational and training services in the field of ophthalmology; education and training in the use and operation of ophthalmological surgery systems.
