KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sung Man
Noh, Yoon Sang
Abrégé
Provided are an anode active material for a lithium secondary battery including spheronized natural graphite particles. The spheronized natural graphite particles have a structure in which flaky natural graphite fragment particles are agglomerated and granulated into a cabbage shape or random shape, phosphorus (P) atoms are bonded to edge planes of all or some of the flaky natural graphite fragment particles that constitute the interior or surface of the spheronized natural graphite particles, and an amorphous and/or low-crystallinity carbon coating layer is formed on the edge planes and basal planes of all or some of the flaky natural graphite fragment particles, a method of producing the same, and a lithium secondary battery including the same.
H01M 4/02 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif
H01M 4/587 - Matériau carboné, p.ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
2.
NEGATIVE ELECTRODE ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY, METHOD OF PREPARING THE SAME, AND LITHIUM SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE ACTIVE MATERIAL
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sung Man
Jung, Dong Young
Abrégé
Provided are a negative electrode active material for a lithium secondary battery, a method of preparing the same, and a lithium secondary battery including the negative electrode active material. The negative electrode active material includes spheroidized natural graphite particles, wherein the spheroidized natural graphite particles have a structure in which flaky natural graphite fragment particles are grouped and assembled in a cabbage shape or random shape, and a phosphorus (P) atom is bonded to an edge plane of each of all or some particles of the flaky natural graphite fragment particles to modify the spheroidized natural graphite particles, and a portion or the entirety of a surface of the modified spheroidized natural graphite particle is coated with amorphous and/or low-crystallinity carbon.
H01M 4/02 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif
H01M 4/587 - Matériau carboné, p.ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
3.
METHOD OF DIRECTION ESTIMATION FOR NONCIRCULAR SIGNALS VIA DECOUPLED OPTIMIZATION
KANGWON NATIONAL UNIVERSITY-INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Choi, Yang Ho
Abrégé
The disclosure presents a method that estimates the arrival angles of noncircular signals incident on a sensor array based on the ML principle. The complex multidimensional problem according to the ML is transformed into a series of simple problems through the separation of one from the superimposed signals, which leads to the optimization of the function of the two-variable θ and ϕ associated with, respectively, the direction and the initial phase of the separated signal. The optimum value of ϕ is theoretically solved. Then the arrival angle of the separated signal is efficiently estimated through a simple 1-D search with respect to θ. Such an optimization process, updating signal separations, is iterated until the direction estimates converge. The proposed method can be applied also in the presence of Doppler effect.
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sung Man
Jung, Dong Young
Abrégé
The present invention relates to a negative electrode active material for a lithium secondary battery, a method for preparing same, and a lithium secondary battery comprising same, the negative electrode active material being a negative electrode active material for a lithium secondary battery, comprising spheroidized natural graphite particles, wherein the spheroidized natural graphite particles have a structure in which flake-like natural graphite fragment particles are structured and assembled in a cabbage shape or a random shape, the spheroidized natural graphite particles are modified through binding of phosphorus (P) atoms to the edge plane of all or at least part of the flake-like natural graphite fragment particles constituting the surface and inside thereof, and all or part of the surface of the modified spheroidized natural graphite particles is coated with amorphous and/or semi-crystalline carbon.
H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
H01M 4/583 - Matériau carboné, p.ex. composés au graphite d'intercalation ou CFx
H01M 4/133 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif Électrodes pour accumulateurs à électrolyte non aqueux, p.ex. pour accumulateurs au lithium; Leurs procédés de fabrication Électrodes à base de matériau carboné, p.ex. composés d'intercalation du graphite ou CFx
H01M 4/02 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif
5.
ANODE ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY, METHOD FOR PREPARING SAME, AND LITHIUM SECONDARY BATTERY COMPRISING SAME
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sung Man
Noh, Yoon Sang
Abrégé
The present invention relates to an anode active material for a lithium secondary battery, a method for preparing same, and a lithium secondary battery comprising same, the anode active material comprising spheroidized natural graphite particles, wherein: the spheroidized natural graphite particles have a structure in which flaky natural graphite fragment particles are structured and assembled in a cabbage shape or random shape; phosphorus (P) atoms are bonded to the edge plane of all or some of the flaky natural graphite fragment particles constituting the inside or surface of the spheroidized natural graphite particles; and an amorphous and/or semi-crystalline carbon coating layer is formed on the edge plane and the basal plane of all or some of the flaky natural graphite fragment particles.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
6.
ANODE ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY, PREPARATION METHOD THEREFOR AND LITHIUM SECONDARY BATTERY COMPRISING SAME
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sung Man
Kim, Do Hyeon
Abrégé
The present invention relates to an anode active material for a lithium secondary battery, a preparation method therefor and a lithium secondary battery comprising same, the material comprising spherical natural graphite particles, wherein the spherical natural graphite particles have a structure in which flake-like natural graphite fragment particles accumulate and assemble in a cabbage shape or a random shape, and phosphorus (P) atoms are bound to the edge plane of all or at least some of the flake-like natural graphite fragment particles constituting the surface or the inside of the spherical natural graphite particles.
H01M 4/587 - Matériau carboné, p.ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
H01M 4/02 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif
7.
NOVEL CANNABICHROMENIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR IMPROVING COGNITIVE FUNCTION
KANGWON NATIONAL UNIVERSITY-INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Koo Yeon
Jung, Se-Hui
Heo, Hee-Young
Kim, Ju Eun
Lee, Chan Bin
Abrégé
The present invention provides a cannabichromenic acid derivative, a preparation method therefor, and a composition comprising same for improving cognitive function. A novel cannabichromenic acid derivative of the present invention has been confirmed to exhibit not only acetylcholinesterase inhibitory efficacy and butyrylcholinesterase inhibitory efficacy, but also inhibitory efficacy against monoamine oxidase B, and thus reductions in the level of acetylcholine in brain tissues and the level of butyrylcholine in blood, which appear in patients with dementia, can be achieved simultaneously, and by preventing brain cell damage, more effective therapeutic effects of cognitive function improvement can be expected. Therefore, the cannabichromenic acid derivative, the preparation method therefor, and the composition comprising same as an active ingredient for improving cognitive function, of the present invention are substances that simultaneously inhibit acetylcholinesterase, butyrylcholinesterase, and monoamine oxidase B, and can be usefully used as a substance for improving cognitive function in the medicinal and health functional food fields.
C07D 311/04 - Benzo [b] pyrannes non hydrogénés dans le carbocycle
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p.ex. cannabinols, méthanthéline
A61K 31/541 - Thiazines non condensées contenant d'autres hétérocycles
A61K 31/453 - Pipéridines non condensées, p.ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'oxygène comme hétéro-atome du cycle
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
C07D 405/12 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
C07D 413/06 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 407/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
C07D 417/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Seung-Tae
Abrégé
A biodegradable 3D scaffold for skin restoration according to the present invention includes polyethylene glycol-vinylsulfone (PEG-VS), a crosslinking agent, and MFG-E8. When used as a covering material for skin wounds, the 3D scaffold for skin restoration of the present invention can restore the skin while being decomposed in vivo.
A61L 27/60 - Matériaux utilisables pour la peau artificielle
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
INSTITUTE FOR BASIC SCIENCE (République de Corée)
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Sung, Yung Eun
Cho, Yong Hun
Hwang, Won Chan
Abrégé
The present invention comprises a plurality of fuel cell units, which are formed in the shape of a conical cylinder so as to be serially connected to each other, and has one side, with a relatively small outer diameter from among both sides of the fuel cell unit, inserted into the other side with a relatively large outer diameter from among both sides of an adjacent fuel cell unit so that the fuel cell units are serially connected to each other.
H01M 8/2465 - Groupement d'éléments à combustible, p.ex. empilement d'éléments à combustible - Détails des groupements d'éléments à combustible
H01M 8/2457 - Groupement d'éléments à combustible, p.ex. empilement d'éléments à combustible avec les deux réactifs gazeux ou vaporisés
H01M 8/2455 - Groupement d'éléments à combustible, p.ex. empilement d'éléments à combustible avec des réactifs liquides, solides ou chargés en électrolyte
H01M 8/241 - Groupement d'éléments à combustible, p.ex. empilement d'éléments à combustible avec électrolytes solides ou supportés par une matrice
H01M 8/00 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Éléments à combustible; Leur fabrication
H01M 8/0254 - Collecteurs; Séparateurs, p.ex. séparateurs bipolaires; Interconnecteurs caractérisés par la forme ondulé ou dentelé
H01M 8/1004 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Éléments à combustible; Leur fabrication Éléments à combustible avec électrolytes solides caractérisés par les ensembles membrane-électrodes [MEA]
H01M 8/10 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Éléments à combustible; Leur fabrication Éléments à combustible avec électrolytes solides
10.
PHARMACEUTICAL COMPOSITION FOR THICKENING ENDOMETRIUM
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Seung-Tae
Yun, Jung-Im
Kim, Keun-Cheon
Park, Hye-Jin
Abrégé
A pharmaceutical composition according to the present invention comprises a first liquid containing PEG-VS and a second liquid containing a crosslinker inclusive of an amino acid sequence cleaved by a proteinase, wherein the first liquid or the second liquid contains a growth factor.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 47/10 - Alcools; Phénols; Leurs sels, p.ex. glycérol; Polyéthylène glycols [PEG]; Poloxamères; Alkyléthers de PEG/POE
A61K 47/20 - Composés organiques, p.ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant du soufre, p.ex. sulfoxyde de diméthyle [DMSO], docusate, laurylsulfate de sodium ou acides aminosulfoniques
A61K 47/42 - Protéines; Polypeptides; Leurs produits de dégradation; Leurs dérivés p.ex. albumine, gélatine ou zéine
A61K 38/18 - Facteurs de croissance; Régulateurs de croissance
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Sang Il Lee (République de Corée)
Inventeur(s)
Lee, Sang Il
Kim, Hyoung Chun
Ko, Sung Kwon
Shin, Eun Joo
Abrégé
The present invention provides a pharmaceutical composition for preventing or treating Alzheimer's disease and a food composition for relieving symptoms of Alzheimer's disease, which comprise a mountain-cultivated ginseng extract. The composition comprising the mountain-cultivated ginseng extract of the present invention is beneficially used as a pharmaceutical composition for preventing or treating Alzheimer's disease in the medical field for the treatment of Alzheimer's disease or as a food composition for relieving the symptoms of Alzheimer's disease.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
12.
Method of preparing ezetimibe and intermediate thereof
Kangwon National University Industry Cooperation Foundation (République de Corée)
Inventeur(s)
Lee, Phil Ho
Lee, Koo Yeon
Baek, Yonghyeon
Um, Kyusik
Kim, Byeong Su
Abrégé
nd catalyst and deprotection using a Pearlman's catalyst, and an intermediate thereof. The method of preparing ezetimibe is useful as an efficient ezetimibe synthesis technique in pharmaceutical fields using ezetimibe as a raw material.
C07D 263/26 - Atomes d'oxygène liés en position 2 avec des hétéro-atomes ou des radicaux acyle liés directement à l'atome d'azote du cycle
C07D 205/08 - Composés hétérocycliques comportant des cycles à quatre chaînons ne contenant qu'un atome d'azote comme unique hétéro-atome du cycle non condensés avec d'autres cycles comportant une liaison double entre chaînons cycliques ou entre chaînon cyclique et chaînon non cyclique avec un atome d'oxygène lié directement en position 2, p.ex. bêta-lactames
B01J 31/38 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant en outre des composés métalliques inorganiques non prévus dans les groupes du titane, du zirconium ou du hafnium
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Hyoung Chun
Ko, Sung Kwon
Shin, Eun Joo
Abrégé
The present invention provides a pharmaceutical composition for prevention or treatment of Alzheimer's disease and a food composition for alleviation of a symptom of Alzheimer's disease, each composition comprising a mountain-cultivated ginseng extract. A composition comprising a mountain-cultivated ginseng extract of the present invention can be useful as a pharmaceutical composition for prevention or treatment of Alzheimer's disease in the medicinal field for the therapy of Alzheimer's disease or as a food composition for alleviation of a symptom of Alzheimer's disease.
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
14.
BACILLUS LICHENIFORMIS STRAIN NY1505 FOR MASS PRODUCING Α-GLUCOSIDASE INHIBITOR
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Rhee, Haeik
Kim, Hee Woong
Abrégé
The present invention provides Bacillus licheniformis strain NY1505 (accession number KCTC13021BP) for a high yield of an α-glucosidase inhibitor. Bacillus licheniformis strain NY1505, according to the present invention, is a novel strain which can survive in an anaerobic condition, and enables production and supply of an α-glucosidase inhibitor in the intestine and thus maintains a fixed level of effective concentration and shows excellent weight loss and blood glucose lowering effects. And since the Bacillus licheniformis strain NY1505 survives temporarily and does not stay in the intestine, the strain that has been administered when necessary or the α-glucosidase inhibitor produced by means of the strain can be discharged and thus can be safely used. Moreover, separate fermentation cost and processing cost are not required for the production of the α-glucosidase inhibitor and thus the production cost can be reduced. And the present invention does not have the problems of fermentation odor and the like and thus can be applied to various forms of food products.
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Rhee, Haeik
Kim, Hee Woong
Abrégé
The present invention provides a Bacillus subtilis strain (accession number KCTC13020BP) enabling a high yield of thrombolytic enzymes. A Bacillus subtilis strain GDN, according to the present invention, shows notably high thrombolytic enzyme-producing ability compared to existing natto bacteria such as Miyagino bacteria and thus can maintain an equal level of thrombolytic enzyme activities and adjust the ingestion amount of vitamin K2 within the threshold of the recommended daily allowance even when an ingestion amount of natto prepared by means of the Bacillus subtilis strain GDN of the present invention is only one-fifth of an ingestion amount of natto prepared by means of existing natto bacteria. Therefore, the Bacillus subtilis strain GDN can be effectively utilized for preparing various foods for thrombolysis.
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Rhee, Haeik
Abrégé
The present invention relates to a Bacillus subtilis EE5 strain useful for the production of natto with a high content of polyamine, a culture fermented with the same, and a method for producing polyamine by using the same. The Bacillus subtilis EE5 strain of the present invention can be usefully used as a means by which functional natto with a high content of polyamine, a food of high organoleptic quality, can be economically and efficiently provided in the field requiring polyamine-rich functional foods.
C12P 13/00 - Préparation de composés organiques contenant de l'azote
A23L 11/00 - Légumes secs, c. à d. fruits de plantes légumineuses, pour l'obtention d'aliments; Produits dérivés de légumineuses; Leur préparation ou leur traitement
A23L 11/20 - Produits à base de malt; Produits à base de malt fermenté
A23L 33/135 - Bactéries ou leurs dérivés, p.ex. probiotiques
NEGATIVE ELECTRODE ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY COMPRISING CORE COMPOSED OF CARBON, MANUFACTURING METHOD THEREFOR, AND LITHIUM SECONDARY BATTERY INCLUDING SAME
KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sung Man
Shin, Min Seon
Abrégé
A negative electrode active material for a lithium secondary battery, a manufacturing method therefor, and a lithium secondary battery including the same are provided, the negative electrode active material comprising: core particles that include one or more selected from hard carbon, soft carbon and spherical natural graphite; and shell layers located on surfaces of the core particles, wherein the shell layer comprises i) a first shell layer that includes silicon (Si)/carbon black/carbon composite particles, and amorphous or semi-crystalline carbon, and ii) a second shell layer that has a structure in which the amorphous or semi-crystalline carbon is dispersed between flake graphite fragment particles, and the flake graphite fragment particles are stacked and structured in a concentric circle direction, and that is formed on the first shell layer.
KANGWON NATIONAL UNIVERSITY-INDUSTRY COOPERATION FOUNDATION (République de Corée)
DAEHAN PAPER CO., LTD. (République de Corée)
TAEKYUNG POLYMER CO., LTD. (République de Corée)
CENTRE TECHNIQUE DE L'INDUSTRIE DES PAPIERS, CARTONS ET CELLULOSES (France)
Inventeur(s)
Lee, Myoung Ku
Ryu, Jeong Yong
Kim, Chang Geun
Lee, Kwang Seob
Lee, Jae Hoon
Cho, Han Je
Kwon, Hyeok Jun
Guerin, David
Martinez, Philippe
Abrégé
Using the sympathetic printed-matter according to the present invention, a hidden content can be visualized just by wetting. Therefore, it is possible to remove necessities of the sympathetic ink and a special material such as reagent or equipment for visualizing hidden contents. In addition, since the hidden contents disappear by removing water from the sympathetic printed-matter, the sympathetic printed-matter can be used repeatedly. Using the reading confirmation portion, whether or not the sympathetic printed-matter has been read by any other person can be easily determined. In the sympathetic printing method according to the present invention, a hydrophobic substrate can be formed using an existing gas grafting facility, and an ester hydrolase composition and the reading confirmation portion can be formed using an existing printing method. Therefore, a large amount of sympathetic printed-matters can be produced inexpensively and efficiently.
Seoul National University R&DB Foundation (République de Corée)
Kangwon National University Industry Cooperation Foundation (République de Corée)
Inventeur(s)
Yi, Eugene C.
Kang, Min Jueng
Kim, Kristine M.
Kim, Eunhee G.
Abrégé
The present disclosure relates to a method for producing a monoclonal antibody that binds to an epitope for the glycan binding site of a glycoprotein. According to the present disclosure, a monoclonal antibody that recognizes the glycan binding site of a glycoprotein as an epitope can be produced in a relatively simple and economic manner, and a monoclonal antibody having high sensitivity and specificity for the glycan binding site of a glycoprotein can be produced. The monoclonal antibody produced according to the present disclosure can be effectively used as an agent for diagnosing or treating various diseases associated with a change in glycan structure or glycan expression level.
C40B 30/04 - Procédés de criblage des bibliothèques en mesurant l'aptitude spécifique à se lier à une molécule cible, p.ex. liaison anticorps-antigène, liaison récepteur-ligand
C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
C12P 21/06 - Préparation de peptides ou de protéines préparés par hydrolyse d'une liaison peptidique, p.ex. hydrolysats
20.
ANTIOXIDANT COMPOSITION CONTAINING ISORHAMNETIN-3-GLUCOSIDE-7-RHAMNOSIDE SEPARATED FROM HIPPOPHAE RHAMNOIDES LEAVES AS AN ACTIVE INGREDIENT
SAMSUNG HERB MEDICINE CO.,LTD (République de Corée)
KANGWON NATIONAL UNIVERSITY-INDUSTRY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Myong-Jo
Park, Ju-Hee
Kim, Dae-Sung
Kim, Do-Hoon
Han, Sang-No
Abrégé
The present invention relates to an antioxidant composition containing isorhamnetin-3-glucoside-7-rhamnoside (IGR) separated from Hippophae rhamnoides leaves as an active ingredient. The IGR compound separated from the extract of Hippophae rhamnoides leaves according to the present invention has antioxidant, antibiotic, anti-cancer, and anti-inflammatory effects, and therefore may be valuably used as a cosmetic composition for preventing or reducing aging, as an antioxidant health food composition, as an antibiotic pharmaceutical composition, as a pharmaceutical composition for preventing or treating cancer, as a health food composition for preventing or ameliorating cancer, as a pharmaceutical composition for preventing or treating inflammation, and as a health food composition for preventing or ameliorating inflammation.
A61K 31/351 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle non condensés avec un autre cycle
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p.ex. cannabinols, méthanthéline
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p.ex. leucoglucosane, hespéridine, érythromycine, nystatine
HUTECS KOREA PHARMACEUTICAL CO. LTD (République de Corée)
Inventeur(s)
Kim, Hyoung-Chun
Abrégé
The present application describes a composition comprising a neuroprotective effective amount of an antioxidant acetylsalicylic acid maltol ester (AME).
KANGWON NATIONAL UNIVERSITY Industry Cooperation Foundation (République de Corée)
Inventeur(s)
Woo, Heung Myoung
Abrégé
The present invention relates to a method for organ reperfusion in exterior of the animal body which is used in analyzing ischemia/reperfusion injury resulted during organ transplantation process. When transplanting an organ, which was removed during an animal experiment forthe researching purpose, the femoral artery and vein are connected with the artery and vein of the organ using the catheter such that a complex transplantation surgery such as an abdominal incision and blood vessel anastomosis is not necessary. Therefore, there is provided a simple and effective method for organ reperfusion which can exclude surgical factors influencing the result of transplantation, and solve the problems of the researcher's professional skills and the high costs which are problems to be solved in the field of organ transplantation.