|
|
1.
|
HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODS
| Numéro d'application |
19639700 |
| Statut |
En instance |
| Date de dépôt |
2026-04-06 |
| Date de la première publication |
2026-08-13 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
2.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19406162 |
| Numéro de brevet |
12691138 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-12-02 |
| Date de la première publication |
2026-04-09 |
| Date d'octroi |
2026-07-28 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
3.
|
HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODS
| Numéro d'application |
19406290 |
| Statut |
En instance |
| Date de dépôt |
2025-12-02 |
| Date de la première publication |
2026-04-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
4.
|
HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODS
| Numéro d'application |
19406305 |
| Statut |
En instance |
| Date de dépôt |
2025-12-02 |
| Date de la première publication |
2026-04-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
5.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19406370 |
| Numéro de brevet |
12721860 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-12-02 |
| Date de la première publication |
2026-04-09 |
| Date d'octroi |
2026-09-01 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
6.
|
HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODS
| Numéro d'application |
19406402 |
| Statut |
En instance |
| Date de dépôt |
2025-12-02 |
| Date de la première publication |
2026-04-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
7.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19406190 |
| Numéro de brevet |
12702680 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-12-02 |
| Date de la première publication |
2026-04-09 |
| Date d'octroi |
2026-08-11 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
8.
|
MANDOS
| Numéro de série |
99691793 |
| Statut |
En instance |
| Date de dépôt |
2026-03-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 05 - Produits pharmaceutiques, vétérinaires et hygièniques
- 10 - Appareils et instruments médicaux
- 36 - Services financiers, assurances et affaires immobilières
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
pharmaceutical preparations for the prevention and treatment of a variety of ailments and conditions, namely, acute bronchitis, allergies, arthritis, asthma, cancer, cellulitis, cirrhosis, common cold, cold sore, conjunctivitis, cystitis, diabetes, diarrhea, ear infection, fever, fibromyalgia, fungal infection, gastroenteritis, headaches, hemorrhoids, high cholesterol, hyperglycemia, hypoglycemia, indigestion, irritable bowel syndrome, influenza, laryngitis, lyme disease, meningitis, mononucleosis, osteoporosis, pneumonia, pyelonephritis, rosacea, sinusitis, skin abscess, stomach aches, and streptococcal pharyngitis Medical devices for the purposes of lowering cholesterol Business brokerage services and related consulting pertaining to business sales, mergers, acquisitions and business valuations; Intellectual property venture fund management services; Holding company services performed for third parties, namely, investment management Licensing of intellectual property
|
9.
|
MANDOS HEALTH
| Numéro de série |
99691802 |
| Statut |
En instance |
| Date de dépôt |
2026-03-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 05 - Produits pharmaceutiques, vétérinaires et hygièniques
- 10 - Appareils et instruments médicaux
- 36 - Services financiers, assurances et affaires immobilières
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
pharmaceutical preparations for the prevention and treatment of a variety of ailments and conditions, namely, acute bronchitis, allergies, arthritis, asthma, cancer, cellulitis, cirrhosis, common cold, cold sore, conjunctivitis, cystitis, diabetes, diarrhea, ear infection, fever, fibromyalgia, fungal infection, gastroenteritis, headaches, hemorrhoids, high cholesterol, hyperglycemia, hypoglycemia, indigestion, irritable bowel syndrome, influenza, laryngitis, lyme disease, meningitis, mononucleosis, osteoporosis, pneumonia, pyelonephritis, rosacea, sinusitis, skin abscess, stomach aches, and streptococcal pharyngitis Medical devices for the purposes of lowering cholesterol Business brokerage services and related consulting pertaining to business sales, mergers, acquisitions and business valuations; Intellectual property venture fund management services; Holding company services performed for third parties, namely, investment management Licensing of intellectual property
|
10.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19371517 |
| Numéro de brevet |
12667589 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-10-28 |
| Date de la première publication |
2026-02-26 |
| Date d'octroi |
2026-06-30 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
11.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19371542 |
| Numéro de brevet |
12691137 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-10-28 |
| Date de la première publication |
2026-02-26 |
| Date d'octroi |
2026-07-28 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
12.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19371529 |
| Numéro de brevet |
12702678 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-10-28 |
| Date de la première publication |
2026-02-26 |
| Date d'octroi |
2026-08-11 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
13.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19371584 |
| Numéro de brevet |
12702679 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-10-28 |
| Date de la première publication |
2026-02-19 |
| Date d'octroi |
2026-08-11 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
14.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19350933 |
| Numéro de brevet |
12667588 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-10-06 |
| Date de la première publication |
2026-02-05 |
| Date d'octroi |
2026-06-30 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
15.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19350939 |
| Numéro de brevet |
12661371 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-10-06 |
| Date de la première publication |
2026-02-05 |
| Date d'octroi |
2026-06-23 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
16.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19350944 |
| Numéro de brevet |
12611422 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-10-06 |
| Date de la première publication |
2026-02-05 |
| Date d'octroi |
2026-04-28 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
17.
|
LEMBAZ
| Numéro d'application |
019295752 |
| Statut |
Enregistrée |
| Date de dépôt |
2025-12-22 |
| Date d'enregistrement |
2026-05-16 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
05 - Produits pharmaceutiques, vétérinaires et hygièniques
|
Produits et services
Pharmaceutical preparations.
|
18.
|
LEMBAZ
| Numéro d'application |
244412500 |
| Statut |
En instance |
| Date de dépôt |
2025-12-17 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
05 - Produits pharmaceutiques, vétérinaires et hygièniques
|
Produits et services
(1) Pharmaceutical preparations
|
19.
|
LEMBAZ (ADRABETADEX)
| Numéro de série |
99550386 |
| Statut |
En instance |
| Date de dépôt |
2025-12-16 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
05 - Produits pharmaceutiques, vétérinaires et hygièniques
|
Produits et services
Pharmaceutical preparations for the treatment of rare metabolic and neurological disorders and lysosomal storage diseases; Pharmaceutical preparations for the treatment of cholesterol metabolism disorders and lysosomal storage diseases
|
20.
|
LEMBAZ
| Numéro de série |
99550364 |
| Statut |
En instance |
| Date de dépôt |
2025-12-16 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
05 - Produits pharmaceutiques, vétérinaires et hygièniques
|
Produits et services
Pharmaceutical preparations for the treatment of rare metabolic and neurological disorders and lysosomal storage diseases; Pharmaceutical preparations for the treatment of cholesterol metabolism disorders and lysosomal storage diseases
|
21.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19312906 |
| Numéro de brevet |
12667587 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-08-28 |
| Date de la première publication |
2025-12-11 |
| Date d'octroi |
2026-06-30 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
22.
|
HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODS
| Numéro d'application |
19272439 |
| Statut |
En instance |
| Date de dépôt |
2025-07-17 |
| Date de la première publication |
2025-11-20 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
23.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19278356 |
| Numéro de brevet |
12636306 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-07-23 |
| Date de la première publication |
2025-11-13 |
| Date d'octroi |
2026-05-26 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
24.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19278380 |
| Numéro de brevet |
12642813 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-07-23 |
| Date de la première publication |
2025-11-13 |
| Date d'octroi |
2026-06-02 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
25.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19278422 |
| Numéro de brevet |
12648960 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-07-23 |
| Date de la première publication |
2025-11-13 |
| Date d'octroi |
2026-06-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
26.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19219596 |
| Numéro de brevet |
12478635 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-05-27 |
| Date de la première publication |
2025-09-11 |
| Date d'octroi |
2025-11-25 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
27.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19175757 |
| Numéro de brevet |
12453741 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-04-10 |
| Date de la première publication |
2025-08-14 |
| Date d'octroi |
2025-10-28 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
28.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19061509 |
| Numéro de brevet |
12397015 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-02-24 |
| Date de la première publication |
2025-06-19 |
| Date d'octroi |
2025-08-26 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
29.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19061577 |
| Numéro de brevet |
12343358 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-02-24 |
| Date de la première publication |
2025-06-12 |
| Date d'octroi |
2025-07-01 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
30.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
19028631 |
| Numéro de brevet |
12414964 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2025-01-17 |
| Date de la première publication |
2025-05-29 |
| Date d'octroi |
2025-09-16 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
31.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
18533373 |
| Numéro de brevet |
12611421 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2023-12-08 |
| Date de la première publication |
2024-06-06 |
| Date d'octroi |
2026-04-28 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
32.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
18141832 |
| Numéro de brevet |
11918601 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2023-05-01 |
| Date de la première publication |
2024-01-18 |
| Date d'octroi |
2024-03-05 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
33.
|
LONSPYRA
| Numéro de série |
98217379 |
| Statut |
En instance |
| Date de dépôt |
2023-10-10 |
| Propriétaire |
MANDOS LLC (USA)
|
| Classes de Nice ? |
05 - Produits pharmaceutiques, vétérinaires et hygièniques
|
Produits et services
Pharmaceutical preparations for the treatment of rare neurological disorders, not including dermatological disorders
|
34.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
18130132 |
| Numéro de brevet |
11826318 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2023-04-03 |
| Date de la première publication |
2023-08-03 |
| Date d'octroi |
2023-11-28 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
35.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
18115898 |
| Numéro de brevet |
11865136 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2023-03-01 |
| Date de la première publication |
2023-07-20 |
| Date d'octroi |
2024-01-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
36.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
18115901 |
| Numéro de brevet |
11744850 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2023-03-01 |
| Date de la première publication |
2023-07-20 |
| Date d'octroi |
2023-09-05 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
37.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
18115897 |
| Numéro de brevet |
11744849 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2023-03-01 |
| Date de la première publication |
2023-06-29 |
| Date d'octroi |
2023-09-05 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
38.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
18072260 |
| Numéro de brevet |
11744848 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-11-30 |
| Date de la première publication |
2023-03-30 |
| Date d'octroi |
2023-09-05 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
39.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17970080 |
| Numéro de brevet |
11938144 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-10-20 |
| Date de la première publication |
2023-03-02 |
| Date d'octroi |
2024-03-26 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
40.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17946670 |
| Numéro de brevet |
11633423 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-09-16 |
| Date de la première publication |
2023-01-26 |
| Date d'octroi |
2023-04-25 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
41.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17745481 |
| Numéro de brevet |
11541074 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-05-16 |
| Date de la première publication |
2022-09-15 |
| Date d'octroi |
2023-01-03 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
42.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17745516 |
| Numéro de brevet |
11517585 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-05-16 |
| Date de la première publication |
2022-09-15 |
| Date d'octroi |
2022-12-06 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
43.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17745491 |
| Numéro de brevet |
11534456 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-05-16 |
| Date de la première publication |
2022-09-08 |
| Date d'octroi |
2022-12-27 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
44.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17745497 |
| Numéro de brevet |
11590160 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-05-16 |
| Date de la première publication |
2022-09-08 |
| Date d'octroi |
2023-02-28 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
45.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17745505 |
| Numéro de brevet |
11529366 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-05-16 |
| Date de la première publication |
2022-09-08 |
| Date d'octroi |
2022-12-20 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
46.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17745464 |
| Numéro de brevet |
11590159 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-05-16 |
| Date de la première publication |
2022-09-08 |
| Date d'octroi |
2023-02-28 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
47.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17745487 |
| Numéro de brevet |
11534455 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-05-16 |
| Date de la première publication |
2022-09-08 |
| Date d'octroi |
2022-12-27 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
48.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17745470 |
| Numéro de brevet |
11510940 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2022-05-16 |
| Date de la première publication |
2022-09-01 |
| Date d'octroi |
2022-11-29 |
| Propriétaire |
Mandos LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
49.
|
MANDOS HEALTH
| Numéro d'application |
1670548 |
| Statut |
Enregistrée |
| Date de dépôt |
2021-12-17 |
| Date d'enregistrement |
2021-12-17 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 05 - Produits pharmaceutiques, vétérinaires et hygièniques
- 10 - Appareils et instruments médicaux
- 35 - Publicité; Affaires commerciales
- 36 - Services financiers, assurances et affaires immobilières
- 42 - Services scientifiques, technologiques et industriels, recherche et conception
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
Pharmaceutical preparations for the prevention and treatment
of a variety of ailments and conditions. Medical devices for the purposes of lowering cholesterol. Business brokerage services and related consulting
pertaining to business sales. Business brokerage services and related consulting
pertaining to mergers, acquisitions and business valuations
(term considered too vague by the International Bureau -
Rule 13 (2) (b) of the Regulations); intellectual property
venture fund management services; holding company services
performed for third parties, namely, investment management. Research and development of new products, pharmaceutical
preparations, and medical devices; scientific, medical, and
pharmaceutical research and development; drug discovery
services; providing medical and scientific research
information in the field of medicine, medical devices, and
pharmaceuticals; scientific investigations for medical
purposes; conducting research and clinical trials in the
field of medicine, medical devices, and pharmaceuticals. Licensing of intellectual property.
|
50.
|
MANDOS
| Numéro d'application |
1647286 |
| Statut |
Enregistrée |
| Date de dépôt |
2021-12-17 |
| Date d'enregistrement |
2021-12-17 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 05 - Produits pharmaceutiques, vétérinaires et hygièniques
- 10 - Appareils et instruments médicaux
- 36 - Services financiers, assurances et affaires immobilières
- 42 - Services scientifiques, technologiques et industriels, recherche et conception
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
Pharmaceutical preparations for the prevention and treatment
of a variety of ailments and conditions. Medical devices for the purposes of lowering cholesterol. Business brokerage services and related consulting
pertaining to business sales, mergers, acquisitions and
business valuations; intellectual property venture fund
management services; holding company services performed for
third parties, namely, investment management. Research and development of new products, pharmaceutical
preparations, and medical devices; scientific, medical, and
pharmaceutical research and development; drug discovery
services; providing medical and scientific research
information in the field of medicine, medical devices, and
pharmaceuticals; scientific investigations for medical
purposes; conducting research and clinical trials in the
field of medicine, medical devices, and pharmaceuticals. Licensing of intellectual property.
|
51.
|
MANDOS
| Numéro d'application |
018633042 |
| Statut |
Enregistrée |
| Date de dépôt |
2022-01-05 |
| Date d'enregistrement |
2025-09-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 35 - Publicité; Affaires commerciales
- 36 - Services financiers, assurances et affaires immobilières
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
Business brokerage services and related consulting pertaining to business sales, mergers, acquisitions and business valuations. Intellectual property venture fund management services; Financial holding company services performed for third parties, namely, investment management. Licensing of intellectual property.
|
52.
|
MANDOS HEALTH
| Numéro d'application |
018633047 |
| Statut |
Enregistrée |
| Date de dépôt |
2022-01-05 |
| Date d'enregistrement |
2025-09-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 35 - Publicité; Affaires commerciales
- 36 - Services financiers, assurances et affaires immobilières
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
Business brokerage services and related consulting pertaining to business sales, mergers, acquisitions and business valuations. Intellectual property venture fund management services; Holding company services performed for third parties, namely, investment management. Licensing of intellectual property.
|
53.
|
MANDOS
| Numéro d'application |
217012700 |
| Statut |
Enregistrée |
| Date de dépôt |
2021-12-17 |
| Date d'enregistrement |
2024-09-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 05 - Produits pharmaceutiques, vétérinaires et hygièniques
- 10 - Appareils et instruments médicaux
- 36 - Services financiers, assurances et affaires immobilières
- 42 - Services scientifiques, technologiques et industriels, recherche et conception
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
(1) Pharmaceutical and biological preparations for medical use, namely, for the prevention and treatment of lysosomal disorders and elevated cholesterol levels
(2) Medical devices for the purposes of lowering cholesterol (1) Business brokerage services and related consulting pertaining to business sales, mergers, acquisitions and business valuations; Intellectual property venture fund management services; Holding company services performed for third parties, namely, investment management
(2) Research and development of new products, pharmaceutical preparations, and medical devices; providing scientific research information in the fields of pharmaceuticals, medical diagnosis, and treatments; drug discovery services; providing medical and scientific research information in the field of medicine, medical devices, and pharmaceuticals; scientific investigations for medical purposes; Conducting research and clinical trials in the field of medicine, medical devices, and pharmaceuticals
(3) Licensing of intellectual property
|
54.
|
MANDOS HEALTH
| Numéro d'application |
219617500 |
| Statut |
Enregistrée |
| Date de dépôt |
2021-12-17 |
| Date d'enregistrement |
2024-09-09 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 05 - Produits pharmaceutiques, vétérinaires et hygièniques
- 10 - Appareils et instruments médicaux
- 35 - Publicité; Affaires commerciales
- 36 - Services financiers, assurances et affaires immobilières
- 42 - Services scientifiques, technologiques et industriels, recherche et conception
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
(1) Pharmaceutical and biological preparations for medical use, namely, for the prevention and treatment of lysosomal disorders and elevated cholesterol levels
(2) Medical devices for the purposes of lowering cholesterol. (1) Business acquisition and merger consultation.
(2) Business brokerage services and related consulting pertaining to business sales, mergers, acquisitions and business valuations; Intellectual property venture fund management services; Holding company services performed for third parties, namely, investment management
(3) Research and development of new products, pharmaceutical preparations, and medical devices; providing scientific research information in the fields of pharmaceuticals, medical diagnosis, and treatments; drug discovery services; providing medical and scientific research information in the field of medicine, medical devices, and pharmaceuticals; scientific investigations for medical purposes; Conducting research and clinical trials in the field of medicine, medical devices, and pharmaceuticals
(4) Licensing of intellectual property.
|
55.
|
MANDOS HEALTH
| Numéro de série |
97976566 |
| Statut |
Enregistrée |
| Date de dépôt |
2021-12-17 |
| Date d'enregistrement |
2023-11-21 |
| Propriétaire |
Mandos LLC ()
|
| Classes de Nice ? |
42 - Services scientifiques, technologiques et industriels, recherche et conception
|
Produits et services
Research and development of new products, pharmaceutical preparations, and medical devices; scientific, medical, and pharmaceutical research and development; drug discovery services; providing medical and scientific research information in the field of medicine, medical devices, and pharmaceuticals; scientific investigations for medical purposes; Conducting research and clinical trials for others in the field of medicine, medical devices, and pharmaceuticals
|
56.
|
MANDOS HEALTH
| Numéro de série |
97178329 |
| Statut |
En instance |
| Date de dépôt |
2021-12-17 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 05 - Produits pharmaceutiques, vétérinaires et hygièniques
- 10 - Appareils et instruments médicaux
- 36 - Services financiers, assurances et affaires immobilières
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
pharmaceutical preparations for the prevention and treatment of a variety of ailments and conditions, namely, acute bronchitis, allergies, arthritis, asthma, cancer, cellulitis, cirrhosis, common cold, cold sore, conjunctivitis, cystitis, diabetes, diarrhea, ear infection, fever, fibromyalgia, fungal infection, gastroenteritis, headaches, hemorrhoids, high cholesterol, hyperglycemia, hypoglycemia, indigestion, irritable bowel syndrome, influenza, laryngitis, lyme disease, meningitis, mononucleosis, osteoporosis, pneumonia, pyelonephritis, rosacea, sinusitis, skin abscess, stomach aches, and streptococcal pharyngitis Medical devices for the purposes of lowering cholesterol Business brokerage services and related consulting pertaining to business sales, mergers, acquisitions and business valuations; Intellectual property venture fund management services; Holding company services performed for third parties, namely, investment management Licensing of intellectual property
|
57.
|
MANDOS
| Numéro de série |
97178326 |
| Statut |
En instance |
| Date de dépôt |
2021-12-17 |
| Propriétaire |
Mandos LLC (USA)
|
| Classes de Nice ? |
- 05 - Produits pharmaceutiques, vétérinaires et hygièniques
- 10 - Appareils et instruments médicaux
- 36 - Services financiers, assurances et affaires immobilières
- 45 - Services juridiques; services de sécurité; services personnels pour individus
|
Produits et services
pharmaceutical preparations for the prevention and treatment of a variety of ailments and conditions, namely, acute bronchitis, allergies, arthritis, asthma, cancer, cellulitis, cirrhosis, common cold, cold sore, conjunctivitis, cystitis, diabetes, diarrhea, ear infection, fever, fibromyalgia, fungal infection, gastroenteritis, headaches, hemorrhoids, high cholesterol, hyperglycemia, hypoglycemia, indigestion, irritable bowel syndrome, influenza, laryngitis, lyme disease, meningitis, mononucleosis, osteoporosis, pneumonia, pyelonephritis, rosacea, sinusitis, skin abscess, stomach aches, and streptococcal pharyngitis Medical devices for the purposes of lowering cholesterol Business brokerage services and related consulting pertaining to business sales, mergers, acquisitions and business valuations; Intellectual property venture fund management services; Holding company services performed for third parties, namely, investment management Licensing of intellectual property
|
58.
|
MANDOS
| Numéro de série |
97976565 |
| Statut |
Enregistrée |
| Date de dépôt |
2021-12-17 |
| Date d'enregistrement |
2023-11-14 |
| Propriétaire |
Mandos LLC ()
|
| Classes de Nice ? |
42 - Services scientifiques, technologiques et industriels, recherche et conception
|
Produits et services
Research and development of new products, pharmaceutical preparations, and medical devices; scientific, medical, and pharmaceutical research and development; drug discovery services; providing medical and scientific research information in the field of medicine, medical devices, and pharmaceuticals; scientific investigations for medical purposes; Conducting research and clinical trials for others in the field of medicine, medical devices, and pharmaceuticals
|
59.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
17036148 |
| Numéro de brevet |
11406657 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2020-09-29 |
| Date de la première publication |
2021-01-21 |
| Date d'octroi |
2022-08-09 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
60.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
16430664 |
| Numéro de brevet |
10933083 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2019-06-04 |
| Date de la première publication |
2019-09-26 |
| Date d'octroi |
2021-03-02 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
61.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
16372899 |
| Numéro de brevet |
10709730 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2019-04-02 |
| Date de la première publication |
2019-07-25 |
| Date d'octroi |
2020-07-14 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
62.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
16134028 |
| Numéro de brevet |
10300086 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2018-09-18 |
| Date de la première publication |
2019-02-07 |
| Date d'octroi |
2019-05-28 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
63.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
15499831 |
| Numéro de brevet |
10258641 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2017-04-27 |
| Date de la première publication |
2017-10-19 |
| Date d'octroi |
2019-04-16 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
64.
|
Hydroxypropyl beta-cyclodextrin compositions and methods
| Numéro d'application |
15288876 |
| Numéro de brevet |
09675634 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2016-10-07 |
| Date de la première publication |
2017-02-16 |
| Date d'octroi |
2017-06-13 |
| Propriétaire |
MANDOS LLC (USA)
|
| Inventeur(s) |
- Machielse, Bernardus Nicolaas
- Darling, Allan
|
Abrégé
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
|
|