Abrégé

Compositions including Rhodiola rosea, coenzyme Q10, grape extract, alphalipoic acid, and/or quercetin are provided. The compositions may be used for activating mitochondria in a subject. The compositions may modulate the expression of at least one of NRF1, cytochrome C, and/or TFAM in a manner that is independent of PGC-1α. Methods of using the compositions are also provided.

Classes IPC  ?

• A61K 38/54 - Mélanges d'enzymes ou de proenzymes couverts par plus d'un seul des groupes ou
• A61J 1/06 - Ampoules ou cartouches
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
• A61K 31/426 - 1,3-Thiazoles
• A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
• A61K 47/02 - Composés inorganiques

Abrégé

A composition for the topical application on a mammalian skin comprises one or more Brassica plant extracts selected from the group consisting of: Brassica juncea extract, Brassica oleracea italica extract, Brassica oleracea capitata extract, Brassica oleracea botrytis extract, and Brassica oleracea acephala extract. The composition further comprises one or more selected from the group consisting of: Curcuma longa extract, curcuminoids, tetrahydrocurcuminoids, metabolites of curcuminoids or tetrahydrocurcuminoids, and derivatives of curcuminoids or tetrahydrocurcuminoids. The composition further comprises one or more selected from the group consisting of: Camellia oleifera extract, Camellia sinensis extract, green tea extract and white tea extract; Wasabia japonica extract; Bacopa monnieri extract; Silybum marianum extract; and one or both of Piper nigrum extract or tetrahydropiperine.

Classes IPC  ?

• A23L 1/225 - Moutarde
• A61K 36/31 - Brassicaceae ou Cruciferae (famille de la moutarde), p. ex. broccoli, chou ou chou-rave
• A61K 36/9066 - Curcuma, p. ex. curcuma, zédoaire ou curcuma amada
• A61K 36/82 - Theaceae (famille du théier), p. ex. camélia