An objective includes a first lens group, a second lens group configured to move along an optical axis, a third lens group having two or more cemented surfaces, and a fourth lens group including a lens having a convex surface directed to the object side, a lens having a concave surface on an image side, a lens having a concave surface on the object side, and a lens having a convex surface on the image side. The first lens group has three or more lens components including a lens component in which a positive lens having a convex surface on the image side and a meniscus lens having a concave surface on the object side are cemented on outermost object side, and none of the three or more lens components is a cemented lens in which a negative lens is disposed closer to the object side than a positive lens.
G02B 9/34 - Objectifs optiques caractérisés à la fois par le nombre de leurs composants et la façon dont ceux-ci sont disposés selon leur signe, c.-à-d. + ou — ayant uniquement quatre composants
2.
THREE-DIMENSIONAL IMAGE DISPLAY DEVICE, THREE-DIMENSIONAL IMAGE DISPLAY METHOD, AND PROGRAM
This three-dimensional image display device includes a control unit. The control unit sets a reference plane on the basis of one or more points included in three-dimensional image data, and divides the three-dimensional image data into a first region and a second region with the reference plane as a boundary. The control unit superimposes, on a three-dimensional shape of a subject, a graphic having a display state that has been set according to the distance between the reference plane and each of three or more points included in the three-dimensional image data. The control unit sets the gradation of the display state of a first graphic superimposed on the three-dimensional shape corresponding to the first region. The control unit sets the gradation of the display state of a second graphic superimposed on the three-dimensional shape corresponding to the second region.
G02B 23/24 - Instruments pour regarder l'intérieur de corps creux, p. ex. endoscopes à fibres
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
This three-dimensional image display device has a control unit. The control unit displays a three-dimensional shape of a subject on a display on the basis of three-dimensional image data including three-dimensional coordinates of three or more points on the subject. The control unit sets a reference plane on the basis of one or more points included in the three or more points, and divides the three-dimensional image data into a first region and a second region with the reference plane as a boundary. The control unit makes the display state of the three-dimensional shape of the subject in one of the first region and the second region different from the display state of the three-dimensional shape of the subject in the other of the first region and the second region in order to display a cross-section of the subject set on the basis of the reference plane.
G02B 23/24 - Instruments pour regarder l'intérieur de corps creux, p. ex. endoscopes à fibres
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
This measurement device has a control unit. The control unit estimates a curved surface of a specimen on the basis of three or more points on the specimen in three-dimensional data including the three-dimensional coordinates of the three or more points. The control unit acquires a first reference value indicating the absolute size of the curved surface, and calculates a second reference value indicating the relative size of the curved surface. The control unit measures the relative size of the specimen on the basis of one or more points in the three-dimensional data. The control unit converts the relative size of the specimen into an absolute size of the specimen on the basis of the first reference value and the second reference value.
G01B 11/24 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer des contours ou des courbes
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
G02B 23/24 - Instruments pour regarder l'intérieur de corps creux, p. ex. endoscopes à fibres
5.
SAMPLE IMAGE ACQUISITION DEVICE AND SAMPLE IMAGE GENERATION DEVICE
A sample image acquisition device includes a first optical system configured to form a first optical image of a sample, a second optical system configured to form a second optical image of the sample, a moving mechanism, and an image generation unit. A fluorescent image group is generated based on the first optical image, and a bright field image group is generated based on the second optical image. The image generation unit includes a processor. The processor calculates an estimation image of an estimation sample using a refractive index distribution of the estimation sample, calculates, as a final refractive index distribution, the refractive index distribution optimized using a bright field image and the estimation image, calculates a point spread function using the final refractive index distribution, and generates an image corresponding to a fluorescent image, using the point spread function and the fluorescent image of an area.
A storage stores at least one trained models trained by using at least one microscopic videos, microscopic videos associated with each of the trained models, annotation information (including classifications for video segments included in the microscopic videos) indicating annotations assigned to the microscopic videos, and classification criterion information indicating a classification assignment criterion. The processor receives a selection of at least one trained model, acquires microscopic videos, annotation information, and classification criterion information associated with the selected trained model from the storage, displays the acquired microscopic videos and the acquired annotation information in association with each other on a display, and displays the acquired classification criterion information on the display.
G06V 10/96 - Gestion de tâches de reconnaissance d’images ou de vidéos
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
G06V 20/40 - ScènesÉléments spécifiques à la scène dans le contenu vidéo
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
G06V 20/70 - Étiquetage du contenu de scène, p. ex. en tirant des représentations syntaxiques ou sémantiques
7.
RE-LEARNING SUPPORT SYSTEM, RE-LEARNING SUPPORT METHOD, AND STORAGE MEDIUM
A storage stores one or more trained models trained using at least one microscopic image, one or more revisions associated with each of the trained models and indicating versions of the trained model, and one or more pieces of design information for the trained model associated with the one or more revisions. The processor receives a selection of at least one of the trained models, acquires one or more revisions and one or more pieces of design information for the selected trained model from a storage, displays a name of the selected trained model in a first display area of a model design information screen, and displays the acquired revisions and the acquired design information in association with each other in a second display area of the model design information screen.
G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
G06V 10/70 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique
G06V 10/776 - ValidationÉvaluation des performances
G06V 10/94 - Architectures logicielles ou matérielles spécialement adaptées à la compréhension d’images ou de vidéos
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
09 - Appareils et instruments scientifiques et électriques
Produits et services
Microscopes; optical machines and apparatus; electronic
control apparatus for machines; electronic components used
in machines; computers; computer peripheral devices; data
processing apparatus; computer software for controlling
microscopes; computer software for analyzing microscopic
images; computer software.
9.
SCORE CALCULATION DEVICE, MICROSCOPE SYSTEM, SCORE CALCULATION METHOD, AND PROGRAM
This score calculation device for calculating an image-quality score of a microscope image includes: an acquisition unit that acquires a generated image of an object by inputting an object microscope-image, acquired using a microscope, into an image generation model that outputs an output image for which image quality is improved with respect to an input image; and a calculation unit that calculates, as an image-quality score of the microscope image, a score indicating the similarity between the microscope image and the generated image acquired by the acquisition unit.
An inspection assistance system includes an image sensor and a processor. The processor acquires two or more first images from the image sensor in accordance with rotation of a rotor. The processor adds observation information indicating that observation is necessary to at least one first image of the two or more first images. The processor outputs a control signal to a turning tool such that an insertion unit captures an object that is visible in the at least one first image in a field of view. The processor acquires at least one second image from the image sensor after the turning tool has rotated the rotor.
G01M 15/14 - Test des moteurs à turbine à gaz ou des moteurs de propulsion par réaction
F01D 21/00 - Arrêt des "machines" ou machines motrices, p. ex. dispositifs d'urgenceDispositifs de régulation, de commande ou de sécurité non prévus ailleurs
G01N 21/88 - Recherche de la présence de criques, de défauts ou de souillures
09 - Appareils et instruments scientifiques et électriques
Produits et services
Electronic data processing apparatus and their parts;
computer software; computer software for analyzing
fluorescence images; computer software for analyzing
microscopic images; computer software for deconvolution of
microscopic images.
An endoscope system includes an endoscope device including a bendable insertion unit, an operation device, and a processor. A user interface of the operation device generates a first signal in accordance with a state of the user interface. The state changes when the user interface touches an object. A motion sensor of the operation device generates a second signal in accordance with physical movement of the operation device. The processor is configured to calculate a first control value used in first control based on the first signal. The processor is configured to calculate a second control value used in second control based on the second signal. At least one of the first control and the second control is executed to bend the insertion unit.
An inspection assistance device includes a processor. The processor connects to a storage medium that stores inspection requirement information indicating an inspection requirement determined in advance for each inspection target and acquires the inspection requirement information from the storage medium. The processor acquires inspection state information indicating an inspection state by confirming a state of an inspection device used to inspect the inspection target. The processor compares the inspection requirement information with the inspection state information and generates comparison result information indicating a comparison result. The processor outputs the comparison result information.
This selection assistance system for an optical adapter mounted to the tip of an endoscope insertion part comprises a storage part that stores type information of each of a plurality of optical adapters and evaluation information corresponding to each of the plurality of pieces of type information, and a control part. The evaluation information includes subject information, or optical index information of the optical adapter of corresponding type information. The control part acquires input information, identifies one or more pieces of evaluation information on the basis of the input information, extracts one or more pieces of type information corresponding to the identified one or more pieces of evaluation information from the storage part, generates assistance information including the extracted one or more pieces of type information, and outputs the assistance information.
This endoscope device includes: a bundle fiber 40 that has a base end 41 and a tip 42 and transmits a luminous flux incident from the base end 41 to the tip 42; a light source 71 that is arranged on the base end 41 side of the bundle fiber 40 and emits the luminous flux to be incident on the bundle fiber 40; a Ronchi ruling 150 that is arranged on the tip 42 side of the bundle fiber 40 and modulates the intensity distribution of the luminous flux emitted from the bundle fiber 40; and a control part that shifts an emission region 43 of the tip 42 of the bundle fiber 40 emitting the luminous flux incident on the Ronchi ruling 150 with respect to the bundle fiber 40 in the cross-sectional direction of the bundle fiber 40.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
A61B 1/07 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement utilisant des moyens conduisant la lumière, p. ex. des fibres optiques
G02B 23/26 - Instruments pour regarder l'intérieur de corps creux, p. ex. endoscopes à fibres utilisant des guides de lumière
09 - Appareils et instruments scientifiques et électriques
Produits et services
Microscopes; optical machines and apparatus; electronic control apparatus for machines; electronic components used in machines; computers; computer peripheral devices; data processing apparatus; computer software for controlling microscopes; computer software for analyzing microscopic images; computer software
This imaging system includes an image sensor and a control unit. The control unit acquires, from the image sensor, four or more images including two or more first images generated under first imaging conditions and two or more second images generated under second imaging conditions. The control unit calculates the amount of motion that occurs between a reference image included among the four or more images and an image which is not the reference image and is included in the four or more images, and sets, on the basis of the amount of motion, an image group including three or more images from among the four or more images. The control unit generates motion compensation information used to compensate for motion in the image group. The control unit generates, on the basis of the motion compensation information and the images included in the image group, three-dimensional information of a subject.
G02B 23/24 - Instruments pour regarder l'intérieur de corps creux, p. ex. endoscopes à fibres
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
09 - Appareils et instruments scientifiques et électriques
Produits et services
Downloadable software applications for displaying images and videos of objects acquired by industrial endoscopes and generating and measuring 3D data; downloadable computer software for displaying images and videos of objects acquired by industrial endoscopes and generating and measuring 3D data; endoscopic equipment for industrial purposes
09 - Appareils et instruments scientifiques et électriques
Produits et services
Electronic data processing apparatus and their parts; computer software; computer software for analyzing fluorescence images; computer software for analyzing microscopic images; computer software for deconvolution of microscopic images.
A chart has a chart pattern for evaluation of an imaging optical system. The chart pattern includes a plurality of closed regions having the same shape including two orthogonal sides in a contour thereof. Each of the plurality of closed regions includes a bright portion having a circular shape and a dark portion surrounding the bright portion. The plurality of closed regions includes a central closed region arranged at a center of the chart pattern and a plurality of peripheral closed regions arranged radially from the center on concentric circles about the center.
An image-processing method includes a measurement step, an index calculation step, a comparison step, and a selection step. A processor measures a distance at each of two or more points in one or more images of a subject in the measurement step. The processor calculates a first index or a second index on the basis of the distance in the index calculation step. The processor compares the first index or the second index with a threshold value in the comparison step. The processor selects at least one image included in the one or more images in the selection step when the first index is greater than the threshold value or the second index is less than the threshold value.
G01C 11/02 - Dispositions de prises de vues spécialement adaptées pour la photogrammétrie ou les levers photographiques, p. ex. pour commander le recouvrement des photos
G06T 7/136 - DécoupageDétection de bords impliquant un seuillage
G06T 7/174 - DécoupageDétection de bords impliquant l'utilisation de plusieurs images
This optical microscope includes an objective lens, a light source that outputs excitation light, and an excitation output measurement unit that measures excitation output, the optical microscope comprising: an image-formation performance measurement unit that measures image-formation performance; and an assessment unit that assesses the performance of the optical microscope on the basis of the results of measuring the image-formation performance and the results of measuring the excitation output.
There is provided a scanning microscope that samples light from a sample irradiated with pulsed light and converts the light into data for each pixel, in which a sampling time per pixel is substantially an integer multiple of a pulse period of the pulsed light, and a sampling start timing of each pixel is synchronized with a pixel synchronization signal.
H04N 25/40 - Extraction de données de pixels provenant d'un capteur d'images en agissant sur les circuits de balayage, p. ex. en modifiant le nombre de pixels ayant été échantillonnés ou à échantillonner
H04N 25/76 - Capteurs adressés, p. ex. capteurs MOS ou CMOS
H04N 25/78 - Circuits de lecture pour capteurs adressés, p. ex. amplificateurs de sortie ou convertisseurs A/N
29.
SCANNING MICROSCOPE, PIXEL GENERATION METHOD, AND STORAGE MEDIUM
A scanning microscope includes: a photodetector that detects light from a sample; a sampling circuit that samples an output signal of the photodetector; and a processor. The processor performs an operation including at least integration on a plurality of items of sampling data sampled by the sampling circuit, determines whether a result of the operation is noise or a signal, and generates pixel data based on a result of the operation and a result of the determination.
An image processing system includes a scanning unit, a pixelated photon detector (PPD), a memory in which a plurality of tables in which an intensity gradation value and an output gradation value are associated with each other are stored, and a processor. The processor generates first image data in which the intensity gradation value indicated by a light intensity signal output from the PPD is set as a pixel value of a constituent pixel based on the light intensity signal and a scanning position of the scanning unit, generates second image data in which the output gradation value is set as a pixel value of a constituent pixel by converting the first image data based on one table selected from the plurality of tables stored in the memory, and causes a display unit to display an image represented by the second image data.
A processor of a three-dimensional data generation system is configured to determine whether two or more images include a graphics region in which graphics information is superimposed. The processor is configured to execute first processing when the two or more images do not include the graphics region. The first processing includes generation processing of generating the three-dimensional data by using the two or more images. The processor is configured to execute second processing when at least one image of the two or more images includes the graphics region. The second processing includes processing of preventing the graphics region in the at least one image from contributing to generation of the three-dimensional data.
G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie
G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
A microscope system includes: a microscope that forms an optical observation image; an image capturing device that captures the optical observation image and generates an observation image; a processor that generates a histogram plotting pixel values of every color component in the observation image, determines a black balance adjustment value based on the histogram plotting pixel values of every color component, and subtracts the black balance adjustment value from pixel values of every color component in each pixel of the observation image to generate an adjusted observation image; and an output device that outputs the adjusted observation image.
This microscope system comprises: a microscope optical system that includes an eyepiece lens and forms an intermediate image of an observation object on an object side of the eyepiece lens; a sensing device (500) that is different from a microscope camera; a control unit that outputs an auxiliary image including work assistance information which is determined on the basis of a work condition with respect to the observation object, said work condition being specified from work information acquired by the sensing device (500), and reference information corresponding to the work condition, said reference information being acquired from a storage unit; and a superimposition device that superimposes the auxiliary image outputted by the control unit on the image plane on which the intermediate image is formed.
A microscope system includes a microscope, a digital camera configured to image an object through the microscope, and a processor. The processor is configured to perform scene recognition based on an image of the object obtained by the digital camera, using a machine learning model that has learned a plurality of scenes, to perform scene determination based on a result of the scene recognition, to temporally stabilize a result of the scene determination, and to change settings of the digital camera based on the result of the scene determination.
H04N 23/68 - Commande des caméras ou des modules de caméras pour une prise de vue stable de la scène, p. ex. en compensant les vibrations du boîtier de l'appareil photo
G02B 7/00 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
G06V 10/70 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
H04N 23/61 - Commande des caméras ou des modules de caméras en fonction des objets reconnus
36.
WORK IMPROVEMENT SUPPORT SYSTEM, WORK IMPROVEMENT SUPPORT METHOD, AND PROGRAM
A work improvement support system (1) comprises: a work data generation unit (21) that generates work data by attaching, to a microscope image acquired by a microscope device (10) during the work of assembling or inspecting equipment using the microscope device (10), tag information relating to the work at the time of the acquisition of the microscope image; a quality information generation unit (22) that, on the basis of a plurality of sets of work data generated by the work data generation unit (21), generates quality information relating to the quality of the work for each work data classification classified by the tag information; and a display control unit (23) that displays the quality information generated by the quality information generation unit (22) on a display device (30).
An observation apparatus includes a display apparatus that displays a display pattern, a display projection optical system that projects a light beam from the display apparatus and forms an image of the display pattern, a combining optical element that combines a light beam from a sample and the light beam from the display apparatus, and an eyepiece optical system through which an image of the sample and an image of the display pattern are simultaneously observable by an observer. A numerical aperture (NA) of the light beam from the display apparatus is smaller than a maximum value and larger than a minimum value of an NA of the light beam from the sample, at a position of an image on an optical path that is formed after the light beams from the sample and the display apparatus are combined by the combining optical element.
The light measurement device includes: a photodetector that detects pulsed signal light and outputs a detection signal including an exponential response; an A/D conversion circuit that converts the detection signal into a digital signal; and a processor that performs setting of a transformation matrix for inversely converting the digital signal, and inverse conversion of the digital signal by the set transformation matrix to calculate an estimated pulse of the signal light.
A three-dimensional data generation method includes the following processing. A processor acquires two or more images of a component inside a turbine. The processor detects two or more correspondence regions that are the same regions in at least two images. The processor determines whether at least part of a region of each image is a change region or a non-change region. The processor generates three-dimensional data by using a correspondence region determined to be the change region without using a correspondence region determined to be the non-change region.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Software applications for industrial endoscopes; computer software; endoscopic equipment for industrial purposes.
42.
REFRACTIVE INDEX DISTRIBUTION GENERATION DEVICE, REFRACTIVE INDEX DISTRIBUTION GENERATION METHOD, REFRACTIVE INDEX DISTRIBUTION GENERATION SYSTEM, AND RECORDING MEDIUM
A refractive index distribution generation device includes a processor and a memory. The processor performs a refractive index distribution generation process of generating a refractive index distribution corresponding to a processing-target image. The refractive index distribution generation process includes an input process of inputting, from the memory, the processing-target image, first refractive index information indicating a refractive index of a first structure, and second refractive index information indicating a refractive index of a second structure different from the first structure, and a setting process of setting respective refractive indexes that constitute a refractive index distribution. The setting process includes a first setting process of setting a refractive index based on the first refractive index information at a position corresponding to a first image region of the processing-target image on the basis of a signal intensity, and a second setting process of setting a refractive index based on the second refractive index information at a position corresponding to an image region different from the first image region of the processing-target image. The first image region is an image region corresponding to the first structure.
G01N 21/27 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en utilisant la détection photo-électrique
43.
OBSERVATION SYSTEM, FOCUS POSITION CALCULATION METHOD, AND COMPUTER READABLE MEDIUM
An observation system includes: an illumination device that illuminates an observation object with illumination light from a plurality of different directions; an imaging device that includes an objective that condenses light from the observation object and images the observation object with the light collected by the objective; and a control unit. The control unit calculates a focus position of the imaging device based on a plurality of image groups acquired by the imaging device at observation positions different from each other in an optical axis direction of the objective, each of the plurality of image groups including a plurality of images of the observation object illuminated from directions different from each other by the illumination device.
G02B 7/38 - Systèmes pour la génération automatique de signaux de mise au point utilisant des techniques liées à la netteté de l'image mesurée en différents points de l'axe optique
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
H04N 23/67 - Commande de la mise au point basée sur les signaux électroniques du capteur d'image
H04N 23/74 - Circuits de compensation de la variation de luminosité dans la scène en influençant la luminosité de la scène à l'aide de moyens d'éclairage
44.
SAMPLE IMAGE GENERATION DEVICE, SAMPLE IMAGE GENERATION METHOD, SAMPLE IMAGE GENERATION SYSTEM, AND RECORDING MEDIUM
A sample image generation device includes a memory and a processor. A first image is an image obtained by capturing an image of a sample. A predetermined direction in the first image is a direction in which a virtual observation optical system is present among optical axis directions of the virtual observation optical system. The processor acquires the first image from the memory, divides the first image into a plurality of areas, acquires a refractive index distribution of the sample from the memory, calculates a point spread function using the refractive index distribution, generates second images using the point spread function, combines the second images, and generates a third image corresponding to the first image. In the calculation process, the point spread function of a first area is calculated using the refractive index distribution of each area included in an area group. The first area is an area for which the point spread function is to be calculated. The area group is constituted of a plurality of areas inside a range in which light rays originating from the first area radiate in the predetermined direction.
G06V 10/60 - Extraction de caractéristiques d’images ou de vidéos relative aux propriétés luminescentes, p. ex. utilisant un modèle de réflectance ou d’éclairage
G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
09 - Appareils et instruments scientifiques et électriques
Produits et services
Optical inspection apparatus; Optical inspection apparatus, namely, a digital slide inspection system comprising microscopes, digital cameras, and digital slide scanners, for capturing digital images and processing imaging data for use in research laboratories; microscopes; lenses for microscopes; interfaces for computers; downloadable computer software applications, namely, optical imaging software applications for use in the field of optical image scientific analysis; recorded computer software for optical imaging for use in the field of scientific research and industrial imaging; recorded computer software for data processing and image measuring for use with microscopes in research laboratories; data processing equipment, namely, scanners; electric light dimmers regulators
An objective includes a positive first lens group, a negative second lens group, and a positive third lens group including two or more lens components, in which the first, second, and third lens groups are sequentially disposed from an object side. The first lens group includes a meniscus-shaped first lens having positive refractive power, in which the first lens has a concave surface facing an image side, and a meniscus-shaped second lens having positive refractive power, in which the second lens has a concave surface facing the image side. The second lens group includes two or more positive lenses and one or more negative lenses. The total number of lenses included in the second lens group is seven or more. The objective satisfies the following conditional expressions.
An objective includes a positive first lens group, a negative second lens group, and a positive third lens group including two or more lens components, in which the first, second, and third lens groups are sequentially disposed from an object side. The first lens group includes a meniscus-shaped first lens having positive refractive power, in which the first lens has a concave surface facing an image side, and a meniscus-shaped second lens having positive refractive power, in which the second lens has a concave surface facing the image side. The second lens group includes two or more positive lenses and one or more negative lenses. The total number of lenses included in the second lens group is seven or more. The objective satisfies the following conditional expressions.
1.6
≤
fL
/
TTL
≤
5
(
1
)
2
≤
ER
1
F
/
ER
2
F
(
2
)
1.29
≤
ER
3
F
/
ER
2
R
(
3
)
G02B 9/14 - Objectifs optiques caractérisés à la fois par le nombre de leurs composants et la façon dont ceux-ci sont disposés selon leur signe, c.-à-d. + ou — ayant uniquement trois composants disposés + — +
This inspection assistance system has an image sensor and a control unit. The control unit acquires two or more first images from the image sensor in response to the rotation of a rotating body. The control unit adds observation information indicating that observation is necessary to at least one first image among the two or more first images. The control unit outputs a control signal to a turning tool in order for the insertion part to capture, in the field of view, an object appearing in the at least one first image. After the turning tool rotates the rotating body, the control unit acquires at least one second image from the image sensor.
09 - Appareils et instruments scientifiques et électriques
Produits et services
downloadable software applications for displaying images and videos of objects acquired by industrial endoscopes and generating and measuring 3D data; downloadable computer software for displaying images and videos of objects acquired by industrial endoscopes and generating and measuring 3D data
53.
OBSERVATION DEVICE, OBSERVATION SYSTEM, AND METHOD FOR CONTROLLING OBSERVATION DEVICE
An observation device includes: an illumination system that is disposed on a downward side of a sample and emits illumination light from the downward side toward an upward side of the sample; an imaging system that is disposed on the downward side and images the sample with transmitted light that is reflected on the upward side in the illumination light emitted from the illumination system and is transmitted through the sample from the upward side to the downward side; and a control unit that executes imaging control using the illumination system and the imaging system. The control unit controls an exposure amount in correspondence with required time for the imaging control which includes required operation time and required pause time determined based on imaging conditions.
H04N 23/72 - Combinaison de plusieurs commandes de compensation
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
H04N 23/73 - Circuits de compensation de la variation de luminosité dans la scène en influençant le temps d'exposition
H04N 23/74 - Circuits de compensation de la variation de luminosité dans la scène en influençant la luminosité de la scène à l'aide de moyens d'éclairage
09 - Appareils et instruments scientifiques et électriques
Produits et services
Downloadable software applications for displaying images and videos of objects acquired by industrial endoscopes and generating and measuring 3D data; downloadable computer software for displaying images and videos of objects acquired by industrial endoscopes and generating and measuring 3D data; endoscopic equipment for industrial purposes
55.
METHOD OF EXTRACTING GENE CANDIDATE, METHOD OF UTILIZING GENE CANDIDATE, AND COMPUTER-READABLE MEDIUM
A microscope image of a cultured cell cluster derived from a cancer specimen of a patient is acquired. A measured value of a gene expression level of the cluster is acquired. Based on the image, a morphological representation identifiably expressing, by a vector quantity of a plurality of dimensions, a morphological difference between a group of cell clusters cultured from the same cancer specimen and a group of cell clusters cultured from another cancer specimen is acquired. The acquired morphological representation is input to a function, which is obtained by fitting the measured value with respect to the morphological representation, to acquire a prediction value of the gene expression level. Prediction accuracy is estimated based on the prediction value and the measured value. Based on the estimated prediction accuracy, a gene related to a morphological change of the cell cluster is extracted as a gene candidate.
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
An endoscope system according to the present invention has: an endoscope device having a bendable insertion part; an operation device; and a control unit. A user interface of the operation device generates a first signal according to a state of the user interface that changes when contact is made with an object. A motion sensor of the operation device generates a second signal according to a physical motion of the operation device. The control unit calculates, on the basis of the first signal, a first control value to be used for first control. The control unit calculates, on the basis of the second signal, a second control value to be used for second control. At least one of the first control and the second control is performed to bend the insertion part.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
G02B 23/24 - Instruments pour regarder l'intérieur de corps creux, p. ex. endoscopes à fibres
57.
Image display method, display control device, and recording medium for displaying shape image of subject and coordinates estimated from two-dimensional coordinates in reference image projected thereon
A processor causes a storage medium to store three-dimensional data of a subject in a storage step. The processor selects a reference image in a first selection step. The processor selects a selected image that is a two-dimensional image used for generating the three-dimensional data on the basis of the reference image in a second selection step. The processor estimates a second camera coordinate regarding the reference image on the basis of a first camera coordinate regarding the selected image in an estimation step. The processor displays an image of the subject on a display in a display step. The image of the subject visualizes at least one of the second camera coordinate and a set of three-dimensional coordinates of one or more points of the subject calculated on the basis of the second camera coordinate.
G06T 7/70 - Détermination de la position ou de l'orientation des objets ou des caméras
F02C 7/00 - Caractéristiques, parties constitutives, détails ou accessoires non couverts dans, ou d'un intérêt plus général que, les groupes Entrées d'air pour ensembles fonctionnels de propulsion par réaction
58.
ENDOSCOPE DEVICE, METHOD OF OPERATING ENDOSCOPE DEVICE, AND RECORDING MEDIUM
An endoscope device includes an imaging device, a determination unit, and a control unit. The determination unit is configured to determine the position and the size of a region including the distal end of a treatment tool seen in an image. The control unit is configured to set a control region in the image based on the position and the size. The control unit is configured to execute exposure control of controlling brightness of the image by using a value of a pixel in the control region. The control unit is configured to display the control region on a display. The control region includes a first region and excludes a second region. The distal end is seen in the first region. Abase end of the treatment tool is seen in the second region. The second region is in contact with a boundary of the image.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
H04N 23/73 - Circuits de compensation de la variation de luminosité dans la scène en influençant le temps d'exposition
H04N 23/74 - Circuits de compensation de la variation de luminosité dans la scène en influençant la luminosité de la scène à l'aide de moyens d'éclairage
A microscope apparatus includes a color temperature adjustment unit. The color temperature adjustment unit includes, in order from an incident side of light: a first polarizer that converts the light into linearly polarized light; a ¼-wave plate that converts at least light of a predetermined wavelength of the linearly polarized light into circularly polarized light, the ¼-wave plate being fixed in a predetermined orientation relative to the first polarizer; and a second polarizer that extracts a predetermined polarization component, the second polarizer being disposed to be rotatable relative to the first polarizer. A difference between a phase amount with respect to light of 435 nm and a phase amount with respect to light of 635 nm of the ¼-wave plate is 30 degrees or more.
OTTL≤0.6 (3) are satisfied.
Herein, fL is a focal length. TTL is the distance from the surface closest to the object side to the surface closest to the image side. ER1 is an effective radius of the surface closest to the object side. ER2 is an effective radius of the surface of the second lens group closest to the object side. D2 is the distance from the object plane to the surface of the second lens group closest to the image side. OTTL is the distance from the object plane to the surface closest to the image side.
G02B 9/64 - Objectifs optiques caractérisés à la fois par le nombre de leurs composants et la façon dont ceux-ci sont disposés selon leur signe, c.-à-d. + ou — ayant plus de six composants
G02B 13/02 - Télé-objectifs photographiques, c.-à-d. systèmes du type + — dans lesquels la distance du sommet de l'angle avant au plan de l'image est inférieure à la distance focale équivalente
G02B 13/18 - Objectifs optiques spécialement conçus pour les emplois spécifiés ci-dessous avec des lentilles ayant une ou plusieurs surfaces non sphériques, p. ex. pour réduire l'aberration géométrique
A sample observation apparatus includes a light source unit, an illumination optical system, an observation optical system, a light detection element, a scanning unit, a holding member, and an image processing device. A light spot is formed by the illumination optical system. The scanning unit moves the light spot and the holding member relative to each other. A pupil of the observation optical system and the light detection element are positioned at a position conjugate to a pupil position of the illumination optical system. The image processing device generates an image of a sample based on a predetermined image and a filter, and the predetermined image is an image based on a signal output from the light detection element. The filter includes a first region and a second region, and a value in the first region is greater than a value in the second region.
An experiment support apparatus includes: one or more non-transitory computer-readable media that include an instruction; and one or more processors that execute the instruction. The instruction is configured to cause the one or more processors to execute an operation, the operation includes: causing a display device to display a condition table TB that indicates an experiment condition for measurement, in response to an input of the experiment condition; and causing the display device to display at least one of a measurement result based on measurement data, or an analysis result of the measurement data, in a cell of the condition table TB, in response to an input of the measurement data, the measurement data being obtained using a measurement apparatus under the experiment condition corresponding to the cell.
This information processing device comprises a storage unit and a control unit. The storage unit stores a plurality of pieces of image data each having a family ID that is not updated when an image is processed and the number of which is uniquely selected only when a test device acquires an image. In accordance with a request from a terminal having a display device, the control unit outputs, to the terminal, display information for displaying one or more pieces of image data (1093, 1093a, 1093b, 1094, 1094a) included in a data set (A32) as a list on a screen, the one or more pieces of image data being from the plurality of pieces of image data. The display information includes group display information (1098, 1099) that groups, by family ID, one or more pieces of image data included in the data set (A32).
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
G06F 16/58 - Recherche caractérisée par l’utilisation de métadonnées, p. ex. de métadonnées ne provenant pas du contenu ou de métadonnées générées manuellement
64.
Three-dimensional image display method, three-dimensional image display device, and recording medium
In a three-dimensional image display method, a processor acquires first three-dimensional data and second three-dimensional data of a subject from a recording medium. The processor converts a first three-dimensional coordinate system of the first three-dimensional data and a second three-dimensional coordinate system of the second three-dimensional data into a three-dimensional common coordinate system on the basis of structure information related to a geometric structure of the subject. The processor displays an image of the first three-dimensional data in the common coordinate system and an image of the second three-dimensional data in the common coordinate system on a display.
H04N 13/111 - Transformation de signaux d’images correspondant à des points de vue virtuels, p. ex. interpolation spatiale de l’image
H04N 13/167 - Synchronisation ou commande des signaux d’images
H04N 13/207 - Générateurs de signaux d’images utilisant des caméras à images stéréoscopiques utilisant un seul capteur d’images 2D
H04N 13/361 - Reproduction d’images stéréoscopiques mixtesReproduction d’images stéréoscopiques et monoscopiques mixtes, p. ex. une fenêtre avec une image stéréoscopique en superposition sur un arrière-plan avec une image monoscopique
65.
MICROSCOPE SYSTEM, SUPERIMPOSITION UNIT, SUPERIMPOSITION DISPLAY METHOD, AND PROGRAM
A microscope system (1) comprises: an eyepiece lens (30); an observation optical system (100); a reading device (50); a superimposition device (25); and a control device (70). The observation optical system (100) forms a specimen image, using observation light from a specimen (S), on an image surface on the object side of the eyepiece lens (30). The reading device (50) reads identification information attached to the specimen (S). The superimposition device (25) superimposes, onto the image surface, specimen information obtained on the basis of the identification information. By controlling the superimposition device, the control device (70) switches the display position of the specimen information on the image surface when prescribed conditions are met.
A three-dimensional reconstruction device includes a processor. The processor is configured to acquire position-and-orientation information and two-dimensional coordinate information. The processor is configured to acquire a three-dimensional size of a subject. The processor is configured to calculate a correction coefficient used for matching the size at the position of a camera to a known size. The processor is configured to correct the position of the camera by using the correction coefficient. The processor is configured to restore a three-dimensional shape of the subject by using the corrected position. the orientation of the camera at the position, and the two-dimensional coordinate information.
An observation system includes a mounting table on which a sample container is placed, a surface light source that is disposed in one of two regions divided by the mounting table and has a light emitting plane, an observation optical system disposed in the other thereof, a conveyance mechanism moving the observation optical system in a direction orthogonal to an optical axis of the observation optical system to change an observation position, and a controller controlling a light emission pattern defined by a light emitting region where light is emitted on the light emitting plane. The controller executes first light emission pattern control in which the light emission pattern is changed according to the observation position, or, alternatively, second light emission pattern control in which the light emission pattern is switched between a plurality of periodic light emission patterns having phases different from each other.
An estimation system has a memory and a processor. The memory stores first wave front information and second wave front information. The first wave front information is information on the wave front that is obtained based on first illumination light that has passed through an object. The second wave front information is information on the wave front that is obtained based on second illumination light that has passed through the object. The wavelength at which the intensity of the second illumination light is highest is shorter than the wavelength at which the intensity of the first illumination light is highest. The processor performs an estimation process of estimating a three-dimensional optical property of the object. The three-dimensional optical property is a refractive index distribution or an absorbance distribution. The estimation process uses both the first wave front information and the second wave front information.
G01N 21/45 - RéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant des méthodes interférométriquesRéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant les méthodes de Schlieren
G01N 21/41 - RéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique
A data processing method includes an input step S1 of inputting measurement data into a neural network, an estimation step S2 of generating estimation data from the measurement data, a restoration step S3 of generating restoration data from the estimation data, and a calculation step S4 of calculating a confidence level of the estimation data, based on the measurement data and the restoration data. The neural network is a trained model, the measurement data is data obtained by measuring light transmitted through an object, the estimation data is data of a three-dimensional optical characteristic of the object estimated from the measurement data, and the three-dimensional optical characteristic is a refractive index distribution or an absorptance distribution. In the estimation, the neural network is used, in the restoration, forward propagation operations are performed on the estimation data, and in the forward propagation operations, wavefronts passing through the interior of the object estimated from the measurement data are sequentially obtained in a direction in which light travels.
A microscope system includes an incoherent light source, a detection optical system, and an imager. The incoherent light source is a light source that emits light that is temporally not coherent. In a sample, a plurality of coherent illuminations are performed simultaneously by light emitted from the incoherent light source. The coherent illuminations are illumination by light that is spatially coherent. The direction in which the sample is irradiated with a light beam is different for each coherent illumination. In a pupil plane of the detection optical system, the respective light beams of the coherent illuminations pass through first regions different from each other. Each of the first regions satisfies the following Condition (1). At least one distance among distances between the two adjacent first regions satisfies the following Condition (2).
A microscope system includes an incoherent light source, a detection optical system, and an imager. The incoherent light source is a light source that emits light that is temporally not coherent. In a sample, a plurality of coherent illuminations are performed simultaneously by light emitted from the incoherent light source. The coherent illuminations are illumination by light that is spatially coherent. The direction in which the sample is irradiated with a light beam is different for each coherent illumination. In a pupil plane of the detection optical system, the respective light beams of the coherent illuminations pass through first regions different from each other. Each of the first regions satisfies the following Condition (1). At least one distance among distances between the two adjacent first regions satisfies the following Condition (2).
LS
An insertion state determination system includes a sensor unit including a first sensor and the system includes a second sensor and a processor. The first sensor is configured to determine a first rotation amount indicating a rotation amount of an elongated insertion unit of an endoscope device around a center axis of the insertion unit. A hole through which the insertion unit passes is formed in the sensor unit. The second sensor is disposed in the sensor unit or an object fixed to the sensor unit and is configured to determine a second rotation amount indicating a rotation amount of the sensor unit around the center axis when the insertion unit is inserted into the subject. The processor is configured to calculate a corrected rotation amount by correcting the first rotation amount based on the second rotation amount.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
72.
Endoscope device, endoscope system, convergence angle changing method, and computer-readable medium
An endoscope device includes an imaging optical system including two incident light paths formed by two optical systems respectively having optical axes eccentric with respect to an imaging center of an imaging element, an optical action member configured to change a convergence angle, and a processor configured to control a state of the optical action member in the imaging optical system. The processor changes the convergence angle by controlling the state of the optical action member in the imaging optical system.
G02B 23/24 - Instruments pour regarder l'intérieur de corps creux, p. ex. endoscopes à fibres
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
G02B 7/18 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques pour prismesMontures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques pour miroirs
G02B 7/28 - Systèmes pour la génération automatique de signaux de mise au point
A microscope system (1) comprises: a microscope (100) that forms an image of a sample containing sperm; an imaging device (143) that acquires the image of the sample; a processing device (200) that generates, on the basis of the acquired image, an auxiliary image containing information related to grading of the sperm; and a projection device (153) that superimposes the auxiliary image onto the image plane where the microscope (100) forms the image. The processing device (200) extracts at least one portion of the sperm from the image by utilizing a segmentation model generated by means of deep learning. The processing device (200) additionally grades the sperm on the basis of a measured value of a feature quantity measured from the at least one portion that was extracted and preregistered grading criteria indicating the relationship between the feature quantity and the grade.
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
74.
ENDOSCOPIC DEVICE, FRAME IMAGE EXTRACTION METHOD, COMPUTER-READABLE MEDIUM, AND ENDOSCOPIC SYSTEM
An endoscopic device includes: an insertion portion that is inserted into a test subject and includes an imaging element; an operation receiving unit; and a processor. The processor, during recording processing of a moving image including a plurality of frame images generated on the basis of an imaging signal output from the imaging element, adds, as a tag, information regarding an operation to a frame image corresponding to a timing when the operation receiving unit receives the operation, and adds, as a tag, information regarding a specific feature image to a frame image recognized as the specific feature image, and extracts a frame image from among the plurality of frame images included in the moving image on the basis of a tag.
A61B 1/05 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision caractérisés par le fait que le capteur d'images, p. ex. l'appareil photographique, est placé dans la partie de l'extrémité distale
G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
A microscope system includes an eyepiece-side observation optical system that forms an image of a sample on an object side of an eyepiece, a camera-side observation optical system that forms an image of the sample on an image sensor, a diaphragm that limits a numerical aperture on the emission side of the camera-side observation optical system, and a processor that analyzes the image of the sample captured by the image sensor. In a case where a numerical aperture on an object side of an objective lens is denoted by NA, the numerical aperture on the emission side of the camera-side observation optical system determined by a light flux emitted from the camera-side observation optical system toward the image sensor at capturing the image is denoted by NA′, and a total magnification of the camera-side observation optical system is denoted by M1, the following is satisfied.
A microscope system includes an eyepiece-side observation optical system that forms an image of a sample on an object side of an eyepiece, a camera-side observation optical system that forms an image of the sample on an image sensor, a diaphragm that limits a numerical aperture on the emission side of the camera-side observation optical system, and a processor that analyzes the image of the sample captured by the image sensor. In a case where a numerical aperture on an object side of an objective lens is denoted by NA, the numerical aperture on the emission side of the camera-side observation optical system determined by a light flux emitted from the camera-side observation optical system toward the image sensor at capturing the image is denoted by NA′, and a total magnification of the camera-side observation optical system is denoted by M1, the following is satisfied.
M1×NA′
A lens-barrel device includes: a relay optical system that relays a primary image formed by an imaging lens to an object plane of an eyepiece to form a secondary image; a first reflection optical system that reflects and bends the light flux from the imaging lens; a second reflection optical system that reflects and bends the light flux that has passed through the first reflection optical system; a third reflection optical system that reflects and bends the light flux that has passed through the second reflection optical system; an additional optical system that transmits the light flux for forming an image different from the secondary image, on the object plane of the eyepiece; and a compositing optical element that guides the light flux from the additional optical system to a light path to the object plane of the eyepiece.
A laser scanning microscope includes a scanner that scans a sample with laser light; a detector having a silicon photomultiplier (SiPM); and a processor that executes image processing of removing dark count noise based on an appearance frequency of the dark count noise in the SiPM on a scanned image.
A microscope system includes an observation optical system that forms an optical image of a specimen on an object side of an ocular lens; a projection device that superimposes information on an image plane on which the optical image is formed, an imaging device that is provided on an imaging optical path branched from an observation optical path, and a processor. The processor controls the projection device to superimpose, on the image plane, focus information based on a captured image of the specimen acquired by the imaging device and analysis information regarding a result of image analysis on the captured image, the image analysis being different from focus analysis.
An objective includes: an objective barrel; a plurality of lens sub-assemblies stacked in an optical axis direction of the objective in the objective barrel, each of the plurality of lens sub-assemblies including a lens and a lens frame holding the lens; and a screw member screwed into the objective barrel, the screw member pressing the plurality of lens sub-assemblies against the objective barrel along the optical axis direction of the objective. The screw member has three or more concave portions into which a jig is fitted when the screw member is screwed into the objective barrel.
An ocular tube for a microscope, to which an ocular lens is to be attached, includes a superimposition device that superimposes an assistive image on an image plane on which an optical image is formed with light from the microscope.
A three-dimensional data generation method includes the following processing. A processor acquires two or more images of a component inside a turbine. The processor detects two or more correspondence regions that are the same regions in at least two images. The processor determines whether at least part of a region of each image is a change region or a non-change region. The processor generates three-dimensional data by using a correspondence region determined to be the change region without using a correspondence region determined to be the non-change region.
Provided is a specimen image generation device with which it is possible to recover an image in a highly accurate manner. This specimen image generation device 1 comprises a memory 2 and a processor 3. A first image is an image obtained by imaging a specimen, and a prescribed direction in the first image is the direction, from among the optical axis directions of a virtual observation optical system, in which the virtual observation optical system is present. The processor 3 acquires the first image from the memory 2, divides the first image into a plurality of areas, acquires the refractive index distribution of the specimen from the memory 2, calculates a point image intensity distribution using the refractive index distribution, generates a second image using the point image intensity distribution, synthesizes the second image, and generates a third image corresponding to the first image. In the calculation process, the point image intensity distribution of a first area is calculated using the refractive index distribution of areas included in an area group, the first area being an area for which the point image intensity distribution is to be calculated, and the area group being configured from a plurality of areas on the inside of a range in which a light beam is radiated in a prescribed direction from the first area.
G01N 21/27 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en utilisant la détection photo-électrique
REFRACTIVE INDEX DISTRIBUTION GENERATION DEVICE, REFRACTIVE INDEX DISTRIBUTION GENERATION METHOD, REFRACTIVE INDEX DISTRIBUTION GENERATION SYSTEM, AND RECORDING MEDIUM
Provided is a refractive index distribution generation device capable of improving the accuracy of a refractive index distribution of even a thick sample. This refractive index distribution generation device comprises a processor and a memory. The processor executes refractive index distribution generation processing of generating a refractive index distribution for a processing target image. The refractive index distribution generation processing includes: input processing of inputting, from a memory, the processing target image, first refractive index information indicating the refractive index of a first structure, and second refractive index information indicating the refractive index of a second structure different from the first structure; and setting processing of setting each refractive index constituting the refractive index distribution. The setting processing includes: first setting processing of setting a refractive index, which is based on the first refractive index information, at a position corresponding to a first image region of the processing target image on the basis of a signal strength; and second setting processing of setting a refractive index, which is based on the second refractive index information, at a position corresponding to an image region different from the first image region of the processing target image. The first image region is an image region corresponding to the first structure.
G01N 21/27 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en utilisant la détection photo-électrique
MOTORIZED CORRECTION COLLAR SYSTEM, METHOD OF CORRECTION COLLAR CALIBRATION PERFORMED BY MOTORIZED CORRECTION COLLAR SYSTEM, AND COMPUTER READABLE MEDIUM
A motorized correction collar system includes: an attachment portion; a control unit that controls transmission of force to a correction collar ring of a first objective lens attached to the attachment portion; and a storage unit that stores calibration information at least for each type of objective lens with a correction collar. The control unit acquires calibration information corresponding to the first objective lens from among the calibration information stored in the storage unit, and calibrates the correction collar of the first objective lens based on the calibration information.
An optical signal detection device includes an objective and a gel unit including a gel and an assisting member. The assisting member includes a first surface, a second surface, and an opening. The opening has a diameter smaller than an outer diameter of the gel and larger than an effective diameter of the objective. The first surface faces the gel, and a part of the first surface is fixed to a bottom surface of the gel by an adhesive force. A center of the bottom surface is not in contact with the assisting member. In a state where the gel unit is attached to a frame member of the objective, the second surface faces the frame member of the objective, a part of the first surface is fixed to the gel outside the effective diameter of the objective, and the gel is in close contact with the objective.
A microscope system includes: a microscope optical system that includes an ocular lens and forms an optical image of a sample on an object side of the ocular lens; a processor that generates auxiliary image data based on information regarding a target slide selected from among a plurality of ordered slides included in a slide set; and a superimposing device that superimposes, based on the auxiliary image data, an auxiliary image including the target slide on an image plane on which the optical image is formed. The processor selects, in response to an instruction to switch the target slide, a slide determined according to a first order in which the plurality of slides are ordered as a new target slide.
An observation apparatus includes: an illumination optical system provided below an installation position of a multi-well plate; a reflector provided above the installation position, the reflector being configured to reflect light emitted from the illumination optical system; and an observation optical system provided below the installation position, the observation optical system being configured to condense the light reflected by the reflector. The reflector is installed such that a marginal ray to enter the observation optical system travels via a peripheral well different from an on-axis well located on an optical axis of the observation optical system before reflection due to the reflector.
A movable optical unit configured to be rotatable around an axis by an electromagnet includes a fixed shaft, a bearing through which the fixed shaft is inserted and which is polarized in a direction orthogonal to a long axis of the fixed shaft, a holding frame that is provided to be rotatable around the fixed shaft and holds at least one optical member, and a pair of arm members extending outward from the holding frame in a direction orthogonal to the long axis of the fixed shaft, the pair of arm members being bonded to the bearing in a state of sandwiching the bearing in a direction along the long axis of the fixed shaft.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
B23K 20/02 - Soudage non électrique par percussion ou par une autre forme de pression, avec ou sans chauffage, p. ex. revêtement ou placage au moyen d'une presse
G02B 7/02 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques pour lentilles
G02B 7/04 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques pour lentilles avec mécanisme de mise au point ou pour faire varier le grossissement
G02B 7/14 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques pour lentilles équipées de lentilles interchangeables
G02B 23/24 - Instruments pour regarder l'intérieur de corps creux, p. ex. endoscopes à fibres
H01F 7/08 - Électro-aimantsActionneurs comportant des électro-aimants avec armatures
A microscope system 1 comprises: a microscope 100 that forms an optical image of a sperm sample which contains an object of selection; an imaging device 143 for acquiring a digital image of the sperm sample; a processing device 200 that generates an object image which is an image of the object of selection, such generation being on the basis of sperm detection and sperm form evaluation with respect to the digital image; and a projection device 153 that displays the object image on an image surface where the optical image is formed, the object image being displayed larger than the object of selection in the optical image.
G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
G01N 33/483 - Analyse physique de matériau biologique
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
91.
IMAGE CAPTURING DEVICE, IMAGE CAPTURING SYSTEM, AND CONTROL METHOD
An image capturing device for observing a sample housed in a container to which identification information is attached, from below the container, includes: an image capturing unit including an image pickup element; a light guide unit that guides light from an identification surface to the image capturing unit, the identification surface being a surface of the container which differs from a bottom surface of the container and to which identification information is attached; and a mobile unit that changes a relative position of the image capturing unit with respect to the container. After the mobile unit changes the relative position to a first relative position in which the optical axis of the image capturing unit deviates from the container, the image capturing unit images the identification surface via the light guide unit, and, after the mobile unit changes the relative position to a second relative position in which the optical axis of the image capturing unit intersects the container, the image capturing unit images the sample via the bottom surface.
|/f≤3.5 (2)
212 is a radius of curvature of a surface closest to the image side in a first meniscus lens component among the pair of meniscus lens components. f is a focal length of the objective.
G02B 9/10 - Objectifs optiques caractérisés à la fois par le nombre de leurs composants et la façon dont ceux-ci sont disposés selon leur signe, c.-à-d. + ou — ayant uniquement deux composants dont l'un + et l'autre —
where d2 is a distance between a surface situated closest to an image side in a first lens component and a surface situated closest to the object side in a second lens component, the first lens component being a lens component situated on the object side and the second lens component being a lens component situated on the image side of the pair of lens components. L is a distance between a surface situated closest to the object side and a surface situated closest to the image side in the objective.
G02B 9/12 - Objectifs optiques caractérisés à la fois par le nombre de leurs composants et la façon dont ceux-ci sont disposés selon leur signe, c.-à-d. + ou — ayant uniquement trois composants
G02B 9/14 - Objectifs optiques caractérisés à la fois par le nombre de leurs composants et la façon dont ceux-ci sont disposés selon leur signe, c.-à-d. + ou — ayant uniquement trois composants disposés + — +
G02B 9/22 - Objectifs optiques caractérisés à la fois par le nombre de leurs composants et la façon dont ceux-ci sont disposés selon leur signe, c.-à-d. + ou — ayant uniquement trois composants disposés + — + dont un seul comporte une lentille composée à savoir le composant central
A microscope system includes: a microscope optical system including an ocular lens, the microscope optical system being configured to form an optical image of a sample on an object side of the ocular lens; a processor configured to generate, based on examination information regarding examination to the sample and magnification information regarding a magnification of the microscope optical system, image data of a comparative image for comparison with the optical image; and a superimposition device configured to superimpose, based on the image data generated by the processor, the comparative image onto an image plane on which the optical image is formed.
A microscope system comprises: a light source; an objective lens; a stage; a two-dimensional image sensor that captures an image of a specimen placed on the stage; a focusing device that changes distance between the objective lens and the stage; and a control circuit, wherein the control circuit executes, during a movement period in which the stage moves in a direction orthogonal to an optical axis of the objective lens, focus control for controlling the focusing device based on focus evaluation information detected during the movement period, and exposure control for controlling an exposure period of the two-dimensional image sensor, and executes light emission control that causes the light source to emit light with different light emission intensities during the exposure period and during a focus evaluation period in which the focus evaluation information is detected.
A system for evaluating stem cell differentiation includes a storage configured to store a machine learned model that has learned success or failure of cell differentiation for a combination of a stem cell and a differentiation induction method, an acquisition unit configured to acquire a target cell image that is an image of a target cell that is a stem cell to be induced to differentiate and differentiation induction information that is information related to a differentiation induction method applied to the target cell, and a processor configured to output differentiation success or failure information indicating an inference result related to success or failure of differentiation of the target cell into a desired cell type on the basis of the target cell image, the differentiation induction information, and the machine learned model. The differentiation induction information includes information indicating the type of a stimulus given to the target cell.
A control method for displaying inspection images causes a processor to display an image of a model of an inspection object including a plurality of inspection sites, in a first display region and display first inspection information relevant to at least one inspection site, in a second display region, where the at least one inspection site is selected from the plurality of inspection sites in the image of the model displayed in the first display region. The control method further causes the processor to display inspection information prior to the first inspection information, as second inspection information relevant to the model, in a third display region, concurrently with one or more of the first display region and the second display region.
In an inspection assistance method, a processor accepts inspection portion information related to an inspection portion. In the inspection assistance method, the processor acquires a result of an inspection of the inspection portion corresponding to the inspection portion information from a storage media: In the inspection assistance method, the processor displays inspection assistance information on a display. The inspection assistance information notifies a user of information related to an abnormality of the inspection portion detected in a previous inspection. In the inspection assistance method, the processor displays an image of the inspection portion on the display.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
An immersion objective includes a first lens group including a meniscus lens, a second lens group including a cemented lens and having a positive power, and a third lens group having a negative power. The third lens group is formed of a front group having a concave surface on a most image side and a back group having a concave surface on the most object side. Even when any of a plurality of immersion liquids used together with the immersion microscope objective is used, an amount of chromatic aberration at each of wavelengths in a range from 435.18 nm to 656.13 nm, which has an e-line as a reference, is smaller than a magnitude of depth of focus of the immersion microscope objective at the wavelength. The immersion microscope objective satisfies a following conditional expression.
An immersion objective includes a first lens group including a meniscus lens, a second lens group including a cemented lens and having a positive power, and a third lens group having a negative power. The third lens group is formed of a front group having a concave surface on a most image side and a back group having a concave surface on the most object side. Even when any of a plurality of immersion liquids used together with the immersion microscope objective is used, an amount of chromatic aberration at each of wavelengths in a range from 435.18 nm to 656.13 nm, which has an e-line as a reference, is smaller than a magnitude of depth of focus of the immersion microscope objective at the wavelength. The immersion microscope objective satisfies a following conditional expression.
0.64≤NA×WD≤3.5 (1)