A process and device for steam sterilization of primary packaging as well as to a primary packaging processed by the process. The primary packaging, such as cartridges, vials, syringes, ampules, or other containers, may be used for pharmaceutical and cosmetic packaging applications. The sterilization process provides reduced water marks on the corresponding primary packaging.
A process and device for steam sterilization of primary packaging as well as to a primary packaging processed by the process. The primary packaging, such as cartridges, vials, syringes, ampules, or other containers, may be used for pharmaceutical and cosmetic packaging applications. The sterilization process provides reduced water marks on the corresponding primary packaging.
A61L 2/07 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques de la chaleur des gaz chauds de la vapeur
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
Method for coating the inside of a glass cylinder with providing a glass cylinder, inserting a spray nozzle into the glass cylinder, praying a silicone solution on the inside of the glass cylinder while moving the nozzle along the longitudinal axis of the cylinder. The resulting inner surface coating is an optically defect free silicone layer.
C03C 17/00 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement
C03C 17/30 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des matières organiques avec des composés contenant du silicium
B05B 13/06 - Machines ou installations pour appliquer des liquides ou d'autres matériaux fluides sur des surfaces d'objets ou de matériaux par pulvérisation, non couverts par les groupes conçus spécialement pour traiter l'intérieur de corps creux
B05D 7/22 - Procédés, autres que le flocage, spécialement adaptés pour appliquer des liquides ou d'autres matériaux fluides, à des surfaces particulières, ou pour appliquer des liquides ou d'autres matériaux fluides particuliers à des surfaces internes, p. ex. à l'intérieur de tubes
4.
SUPPORTING STRUCTURE FOR CONCURRENTLY SUPPORTING A PLURALITY OF CONTAINERS FOR SUBSTANCES FOR PHARMACEUTICAL, MEDICAL OR COSMETIC APPLICATIONS, AND TRANSPORT STRUCTURE COMPRISING THE SAME
A supporting structure for concurrently supporting a plurality of containers for substances for pharmaceutical, medical or cosmetic applications, comprises a plurality of receptacles. The receptacles are arranged in a regular arrangement, are formed by circumferential side-walls, and an upper side of the supporting structure is formed as a plate-shaped carrier. The receptacles are polygonal in shape when viewed in a plan view. A side-wall is formed as a common partition wall between respective two directly adjacent receptacles of the plurality of receptacles. The receptacles can be directly adjacent to each other, which enables optimum packing density, especially with a hexagonal basic shape of the receptacles. Due to the shared partition wall, filigree, double-walled structures can be effectively avoided, which considerably simplifies production by injection molding from a plastic material. Thereby, also a very high inherent stiffness of the supporting structure can be achieved.
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
B65B 43/54 - Moyens pour tenir les réceptacles ou les récipients pendant le remplissage
B65D 1/36 - Plateaux ou réceptacles analogues peu profonds avec compartiments ou cases moulées
B65D 71/70 - Plateaux munis de projections ou de renfoncements afin de rassembler plusieurs objets, p. ex. éléments intermédiaires pour l'empilage
A holding structure for simultaneously holding containers for pharmaceutical, medical, or cosmetic compositions includes: at least ten receptacles for receiving the containers and being formed by side walls; a flat base frame including a central recess; first webs running parallel to each other in a first direction across the central recess; second webs running parallel to each other in a second direction across the central recess, the first webs and the second webs being arranged such that the first webs and the second webs form the side walls, each of the first webs and the second webs being formed as a continuous beam having a maximum waviness wmax of 4.0 mm, the holding structure including a warpage of less than 2.0 mm as determined by a test method before steam sterilization, the warpage corresponding to a bending after the holding structure has been prepared and is empty.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
6.
Tray for filling of vials syringes and cartridges for fill and finish machines
CONTAINER WHICH CAN BE PREFILLED OR IS PREFILLED WITH FLUID, AS WELL AS A CANNULA ASSEMBLY AND CLOSURE SYSTEM FOR A CONTAINER WHICH CAN BE PREFILLED OR IS PREFILLED WITH FLUID
An arrangement includes: a cannula assembly including a cannula including an outside channel opening and a sealing element, the cannula assembly configured to be connected to a receptacle, the sealing element including at least one face side which, in a mounted position, faces the receptacle and includes a passage surrounded by an annular region which forms a face-side sealing surface in a plane perpendicular to a center axis of the sealing element; a closure cap including a sealing, the channel opening of the cannula protruding into the sealing thus sealing the channel opening. Due to radial compression and/or axial compression of the sealing element, as well as due to sealing of the channel opening by the closure cap, a chamber of the receptacle is sealed in a fluid-tight manner when connected to the cannula assembly. An adapter is configured to connect the cannula assembly with the receptacle.
A61M 5/32 - AiguillesParties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchonAccessoires pour introduire l'aiguille dans le corps ou l'y maintenirDispositifs pour la protection des aiguilles
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
A61K 38/48 - Hydrolases (3) agissant sur des liaisons peptidiques (3.4)
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
A61M 5/28 - Ampoules ou cartouches-seringues, c.-à-d. ampoules ou cartouches munies d'une aiguille
A61M 5/34 - Structures pour le raccordement de l'aiguille
8.
GLASS SYRINGE BARREL WITH INCREASED FLANGE BREAKING RESISTANCE
A glass syringe barrel is provided that has a bottom end and a top end with a cone region, a shoulder region, a body region, and a flange region therebetween. The glass syringe barrel is configured so that f(x) defines an absolute value of a vertical distance between any point of a first outer contour and a straight line fo at a position x, with f(x)=0 at point P1, wherein x is a horizontal distance between any given point on the straight line fo and point P0 at which the straight line fo crosses a line L1 that runs parallel to the longitudinal axis and that touches an outer surface of the body region, and a maximum value for the term f(x) in a range from x=P0 to x=P1 is f(x)max determined at position xmax.
A system for storing a pharmaceutical composition at low temperatures includes: a pharmaceutical container having a barrel, a stopper which fluidly closes a first end of the barrel, and a closure which fluidly closes a second end of the barrel; and a liquid pharmaceutical composition and a gas both arranged within the barrel of the container between the stopper and the closure.
A multi-layer sealing film has (a) a layer of a selectively permeable non-woven that is essentially impermeable to microorganisms and (b1) a first layer of film having one or more predefined cut-out regions within an area of the multi-layer sealing film that is to cover an opening of container, or (b2) a first layer of film that is essentially impermeable to a gas or vapor having a first needling, perforation and/or cut pattern within the area of the multi-layer sealing film that is to cover the opening. The layer of a selectively permeable non-woven (a) and the first layer of film (b1) or (b2) are bonded by a sealing seam configured and arranged at least partially subject to and non-overlapping with a sealing seam area for sealing the opening.
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
11.
Holding structure for simultaneously holding a plurality of containers for substances for pharmaceutical, medical or cosmetic applications, transport unit and transport or packaging container having the same
A holding structure includes receptacles formed by peripherally formed side walls, an annular gap being formed between a side wall of a container or device and one of the peripherally formed side walls when containers or devices are received therein, the receptacles being compressed in a first direction and expanded in a second direction transversely thereto, with the result that the gap is widened to form a widened clearance for handling containers or devices which are received in the receptacles, the holding structure further including an upper side, the peripherally formed side walls including an upper edge which forms a closed, smooth curve having at least one local maximum and at least one local minimum in a direction perpendicular to the upper side of the holding structure, the at least one local minimum being situated in a region of the widened clearance that is respectively assigned.
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
B65D 1/36 - Plateaux ou réceptacles analogues peu profonds avec compartiments ou cases moulées
B65D 25/10 - Dispositifs pour placer les objets dans les réceptacles
12.
SYSTEM FOR LONG-TERM STORAGE OF A PHARMACEUTICAL COMPOSITION COMPRISING AN ADAPTER FOR CONNECTING A NEEDLE TO A SYRINGE BARREL
An adapter for connecting a needle to a syringe barrel including a Luer Lock connector having a thread and a cone. The adapter includes: a first part configured to support the needle; a second part including a counter thread configured to form a screwing connection with the thread of the Luer Lock connector; and at least one deformable locking element arranged within a region of the counter thread and protruding radially beyond a minor outer diameter of the counter thread, such that the at least one deformable locking element is configured to be deformed by the thread of the Luer Lock connector when the adapter is screwed to the syringe barrel.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
13.
FRAME FOR HOLDING SECONDARY PHARMACEUTICAL PACKAGING
A frame for holding a secondary pharmaceutical packaging includes: a base plate including at least two openings formed to hold the secondary pharmaceutical packaging; at least two sidewalls connected to the base plate; and at least one stacking element located on the base plate.
A method of determining a tightness of a container includes: providing a container having an initial content at a first temperature, the container including a container body and at least one closure device applied to the container body; exposing the container to an ambient liquid during a first predetermined period of time, where during the first predetermined period of time the ambient liquid has a second temperature different from the first temperature; and after the first predetermined period of time has lapsed, determining a tightness of the container based on an amount of the ambient liquid and/or an amount of the initial content of the container having passed across a boundary of the container.
G01M 3/22 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour tuyaux, câbles ou tubesExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour raccords ou étanchéité de tuyauxExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour soupapes
A glass container for pharmaceutical compositions includes a hollow cylindrical body having at least one open end. At least a part of a surface of the glass container includes a coating. The coating has a crystallization temperature range and a melting temperature range determined using differential scanning calorimetry at a temperature change rate of 10° C./min. The crystallization temperature range and the melting temperature range overlap at a temperature of from −75° C. to −100° C.
A glass syringe barrel is provided that has an at least partially conically shaped upper portion and a longitudinal axis. The glass syringe barrel has a top end through which a liquid can be ejected and a bottom end into which a plunger stopper can be pushed. The glass syringe barrel includes, in a direction from the top end to the bottom end, a cone, a shoulder region, and a body region. The shoulder region has and outer contour that has a concave and substantially circular arc-shaped area c1 with an outer radius r1. The outer contour of the glass syringe barrel in the shoulder region is defined by a certain value for r1.
A61M 5/32 - AiguillesParties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchonAccessoires pour introduire l'aiguille dans le corps ou l'y maintenirDispositifs pour la protection des aiguilles
A61M 5/315 - PistonsTiges de pistonGuidage, blocage, ou limitation des mouvements de la tigeAccessoires disposés sur la tige pour faciliter le dosage
A syringe includes: a container body including an inner wall; a plunger including a plunger rod, the plunger rod being disposed at least partially within the container body; and a locking arrangement configured for locking a position of the plunger rod relative to the container body and for being operable between at least a locked position and an unlocked position, the locking arrangement including at least one deformable element which is configured for applying a locking force between the plunger rod and the inner wall of the container body when the locking arrangement is in the locked position and for releasing the locking force between the plunger rod and the inner wall of the container body when the locking arrangement is changed from the locked position to the unlocked position.
Disclosed is a system for long-term storage of a pharmaceutical composition particularly comprising a syringe. The system comprises an adapter for fixing a needle to the syringe barrel providing improved container closure integrity.
Disclosed is a system for long-term storage of a pharmaceutical composition particularly comprising a syringe. The system comprises an adapter for fixing a needle to the syringe barrel providing improved container closure integrity.
A method of forming a glass vial includes: locally heating one end of a glass tube; removing the locally heated end of the glass tube to form the glass vial having a closed base; and further forming the base of the glass vial, the further forming including generating a purge gas flow within the formed glass vial with the aid of a purge gas.
A holding device, for holding a plurality of primary packaging containers for pharmaceutical, medical, or cosmetic compositions, includes: a plate-shaped carrier element which includes a plurality of through-holes; a plurality of receptacles, each being configured for accommodating a respective one of the plurality of primary packaging containers, each of the plurality of receptacles including a longitudinal direction and a receptacle wall which partially encloses a receptacle interior and forms a wall body, the wall body extending in the longitudinal direction through a respective one of the plurality of through-holes and, for each of the plurality of receptacles, having an interior surface which faces the receptacle interior and an exterior surface which faces opposite to the interior surface, at least 50% of respective ones of the plurality of receptacles having a maximum total height Rt of a roughness profile of the interior surface which is not more than 0.50 mm.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
A holding device for holding packaging containers for pharmaceutical, medical, or cosmetic compositions includes: a plate-shaped carrier element which includes through-holes; receptacles including each a longitudinal direction, a first end, a second end, and a receptacle wall which partially encloses a receptacle interior and forms a wall body, the wall body: extending in the longitudinal direction through a respective one of the through-holes; and including a first opening at the first end, a second opening at the opposite second end, a first edge, and a second edge, the first opening being laterally directly surrounded by the at least one first edge, the second opening being laterally directly surrounded by the second edge, at least 50% of respective ones of the receptacles having a total height Rt of a roughness profile of the first edge and/or the second edge which is not more than 0.50 mm.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
B65D 25/10 - Dispositifs pour placer les objets dans les réceptacles
24.
GLASS SYRINGE BARRELS WITH INCREASED CONE BREAKING FORCES
A glass syringe barrel is provided that has an at least partially conically shaped upper portion and a longitudinal axis. The glass syringe barrel has a top end through which a liquid can be ejected and a bottom end into which a plunger stopper can be pushed. The glass syringe barrel includes, in a direction from the top end to the bottom end, a cone, a shoulder region, and a body region. The shoulder region has and outer contour that has a concave and substantially circular arc-shaped area c1 with an outer radius r1. The outer contour of the glass syringe barrel in the shoulder region is defined by a certain minimum value the radius of curvature.
Apparatuses and methods for inspecting a pharmaceutical cylindrical containers are provided. The apparatus includes a support device, a light emitting unit, and a light receiving unit. The support device supports the pharmaceutical cylindrical container and rotates the cylindrical pharmaceutical container around a longitudinal axis. The light emitting unit has a light source that illuminates the pharmaceutical cylindrical container with a detection beam while the support device rotates the pharmaceutical cylindrical container. The light receiving unit has a camera that acquires polarization information of the detection beam.
G01N 21/01 - Dispositions ou appareils pour faciliter la recherche optique
G01N 21/25 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
G01N 21/958 - Inspection de matériaux transparents
A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
G01N 21/90 - Recherche de la présence de criques, de défauts ou de souillures dans un récipient ou dans son contenu
B65D 1/02 - Bouteilles ou réceptacles similaires, à cols ou à ouvertures rétrécies analogues, conçus pour verser le contenu
B65D 71/06 - Paquets d'objets maintenus ensemble par des éléments d'emballage pour la commodité du stockage ou du transport, p. ex. paquets compartimentés pour le transport à la main de plusieurs réceptacles tels que des boîtes de bière ou des bouteilles de boissons gazeusesBalles de matériaux comprenant plusieurs objets entièrement ou en grande partie reliés par des éléments d'emballage, p. ex. sous tension
max of 4.0 mm; and a support structure connected with the first webs and the second webs and being formed as an outer frame or a plurality of stabilizing ribs in a grid pattern.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
27.
METHOD AND APPARATUS FOR THE HOT FORMING OF GLASS WORKPIECES, AND HOT-FORMED GLASS CONTAINER
A hollow glass article is a container or part of a vessel having a neck or shoulder region and a wall. The glass article encompasses the wall and the neck or shoulder region of the container. The wall has a round or oval cross section and the container has a characteristic surface region on an outer glass surface of the hollow glass article. The following applies for a ratio between a mean tangential gradient value and a mean axial gradient value in the characteristic surface region: mean tangential gradient value/mean axial gradient value <0.6.
A syringe includes a syringe body, a syringe cone having a distal opening, and a connection arranged in the region of the syringe cone, wherein the syringe body includes a first material and the connection includes a second material, and wherein the first material is different from the second material and the second material is a softer material than the first material.
A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
B29C 45/00 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet
B29C 45/16 - Fabrication d'objets multicouches ou polychromes
B29C 65/08 - Assemblage d'éléments préformésAppareils à cet effet par chauffage, avec ou sans pressage avec des vibrations ultrasonores
B29C 65/56 - Assemblage d'éléments préformésAppareils à cet effet en utilisant des moyens mécaniques
B29C 65/00 - Assemblage d'éléments préformésAppareils à cet effet
29.
Method and device for flexibly treating pharmaceutical packages
A method of filling pharmaceutical containers includes: filling a first plurality of containers, the first plurality of containers being supported by a first holder supported on a first step of a first transport and packaging container defining a first step height, the filling includes moving filling needles of a filling device to a filling needle height and dispensing a substance into each of the first plurality of containers; and filling a second plurality of containers, the second plurality of containers being supported by a second holder supported on a second step of a second transport and packaging container defining a second step height equal to the first step height, the filling includes moving the filling needles to the filling needle height and dispensing the substance into each of the second plurality of containers, the second plurality of containers differ from the first plurality of containers in at least one aspect.
B65B 5/06 - Emballage de groupes d'objets, chaque groupe étant traité comme un seul objet
B65B 3/00 - Emballage de matériaux plastiques, de semi-liquides, de liquides ou de liquides et solides mélangés, dans des réceptacles ou récipients individuels, p. ex. dans des sacs ou sachets, boîtes, cartons, bidons ou pots
B65B 55/02 - Stérilisation, p. ex. de paquets finis
B65B 55/08 - Stérilisation des enveloppes d'emballage ou récipients avant ou pendant l'emballage par irradiation
B65B 59/00 - Dispositions pour permettre aux machines de manipuler des objets de différentes dimensions, d’obtenir des paquets de différentes dimensions, de varier le contenu des paquets ou de donner accès pour le nettoyage ou l'entretien
B65D 77/04 - Objets ou matériaux enfermés dans plusieurs réceptacles disposés les uns dans les autres
30.
Separating layer for the transport of pharmaceutical secondary packagings
A separating layer for the transport of pharmaceutical secondary packagings and to a transport system for transporting pharmaceutical secondary packagings which comprises the separating layer are provided. The separating layer is a polymer layer having a planar section extending in an axial direction along a longitudinal axis and an elevation extending normal to the longitudinal axis. The separating layer has in the axial direction a normal spring force that is 0.2 to 5 N.
An arrangement includes a holding device for holding primary packaging containers. The holding device includes: a secondary packaging container which is designed and arranged for accommodating the primary packaging containers; holding elements of a first kind arranged in the secondary packaging container, each holding element of the first kind is designed and arranged to detachably hold a primary packaging container by contacting the primary packaging container at a first longitudinal position of the primary packaging container; and holding elements of a further kind arranged in the secondary packaging container. For each holding element of the first kind, a holding element of the further kind is designed and arranged to restrict a movement of the primary packaging container, which is held by the holding element of the first kind, in a lateral direction of the primary packaging container at a further longitudinal position of the primary packaging container.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
B65D 25/10 - Dispositifs pour placer les objets dans les réceptacles
B65D 77/20 - Fermetures des réceptacles formées après remplissage en appliquant des couvercles ou chapeaux séparés
33.
Holding device comprising first and second components
An arrangement includes a holding device for primary packaging containers including: a first component including first receptacles and spanning a first component plane; and a second component including second receptacles and spanning a second component plane. The first component and the second component superimpose one another such that each primary packaging container can be detachably accommodated in one of the first receptacles and the second receptacles such that the first component and the second component together restrict movement of the primary packaging container in one of the component planes and in a direction which is perpendicular to one of the component planes. For each of the first receptacles, there is one of the second receptacles which has a minimum distance from the first receptacle and, for each of the first receptacles, the minimum distance is predetermined by the second component, a third component of the holding device, or both.
B65D 6/08 - Réceptacles dont le corps est formé par jonction ou liaison de plusieurs composants rigides ou sensiblement rigides, constitués en totalité ou principalement en métal, en matière plastique, en bois ou en un matériau de remplacement de structure à claire voie ou analogue, p. ex. réalisés en matériau flexible entrelacé ou tressé
B65D 71/70 - Plateaux munis de projections ou de renfoncements afin de rassembler plusieurs objets, p. ex. éléments intermédiaires pour l'empilage
B65D 81/05 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu spécialement adaptés pour protéger leur contenu des dommages mécaniques maintenant le contenu en position éloignée des parois de l'emballage ou des autres pièces du contenu
34.
Arrangement comprising a holding device and a plurality of containers with a particle load after a transport simulation
2 of a sum of surface areas of the exterior surfaces of all the containers, the transport simulation consisting of a rotational flat drop test and a random vibration test which are conducted in that order.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
B65B 57/00 - Dispositifs de commande automatique, de vérification, d'alarme ou de sécurité
B65D 25/10 - Dispositifs pour placer les objets dans les réceptacles
B65D 77/00 - Paquets réalisés en enfermant des objets ou des matériaux dans des réceptacles préformés, p. ex. des boîtes, des cartons, des sacs ou des sachets
B65D 77/20 - Fermetures des réceptacles formées après remplissage en appliquant des couvercles ou chapeaux séparés
35.
Pharmaceutical containers and methods for producing, registration, identification and authentication of such containers
Pharmaceutical containers and methods for producing, registration, identification and authentication of such containers and for determining the operation state of machines for producing pharmaceutical containers are provided.
A method for shaping the mouth of a hollow precursor made of glass is provided, as well as glass produced thereby. The method includes heating the mouth of the hollow precursor; introducing a mandrel along a first direction into the mouth while the hollow precursor is rotating; and pressing shaping rollers along a second direction on an outside of the mouth while the hollow precursor is rotating with the mandrel in the mouth. The first and second directions are perpendicular to one another. The method can include moving the mandrel along second and/or third directions together or separate from expanding the mandrel along the second and third directions.
An apparatus for inspecting a pharmaceutical cylindrical container made of glass or of a polymer is provided. A corresponding method for inspecting the pharmaceutical cylindrical container made of glass or of a polymer and to a bundle of pharmaceutical cylindrical containers made of glass or of a polymer is also provided.
An apparatus for inspecting a pharmaceutical cylindrical container made of a polymer, a specific method for inspecting a pharmaceutical cylindrical container made of a polymer and a specific bundle of pharmaceutical cylindrical containers made of a polymer.
G01N 21/892 - Recherche de la présence de criques, de défauts ou de souillures dans un matériau mobile, p. ex. du papier, des textiles caractérisée par la crique, le défaut ou la caractéristique de l'objet examiné
G01N 21/89 - Recherche de la présence de criques, de défauts ou de souillures dans un matériau mobile, p. ex. du papier, des textiles
39.
Holding device for holding a plurality of containers in a positive fit which is established by a displacement movement
A holding device is provided that has a base body having a plurality of openings in a first surface and a plurality of holding elements each having a movable surface. The plurality of holding elements are arranged with respect to the plurality of openings, respectively, such that a container extending in a respective opening of the plurality of openings is held by a respective one of the plurality of holding elements in a positive fit. The movable surface faces the container in a direction that is perpendicular to a height of the container. The holding element establishes the positive fit by a displacement movement of the movable surface. The displacement movement has a direction of movement that inclines an angle with the height of the container in a range from 60 to 120°.
A61M 5/20 - Seringues automatiques, p. ex. avec tige de piston actionnée automatiquement, avec injection automatique de l'aiguille, à remplissage automatique
A transport device for medical containers includes a carrier plate which has openings for receiving medical containers, and optionally a trough-shaped container which is formed such that the carrier plate can be inserted in the trough-shaped container. The carrier plate contains a polymer and 7.5 to 50 wt.-% inorganic particles. The optional trough-shaped container contains a polymer and optionally 7.5 to 50 wt.-% inorganic particles.
A separating layer for the transport of pharmaceutical secondary packagings and to a transport system for transporting pharmaceutical secondary packagings which comprises the separating layer are provided. The separating layer is a polymer layer having a planar section extending in an axial direction along a longitudinal axis and an elevation extending normal to the longitudinal axis. The separating layer has in the axial direction a normal spring force that is 0.2 to 5 N.
tube) while the heated glass tube is still rotating by moving the first and the second chucks away from each other; and moving the heater, while moving the first and second chucks away from each other, so that the heater follows a mass that remains at a circular end region of the first and/or second portion.
C03B 23/11 - Refaçonnage par étirage sans soufflage, en combinaison avec un sectionnement, p. ex. pour fabriquer des ampoules pharmaceutiques
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
B65D 1/02 - Bouteilles ou réceptacles similaires, à cols ou à ouvertures rétrécies analogues, conçus pour verser le contenu
B65D 81/30 - Adaptations pour empêcher la détérioration ou l'altération du contenuApplications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux en excluant la lumière ou toute autre radiation extérieure
C03B 23/08 - Finition des tubes ou des tiges aux dimensions exactes, p. ex. calibrage
C03B 23/09 - Refaçonnage des extrémités, p. ex. rainures, gorges ou embouchures
C03B 33/06 - Découpe ou fendage de tubes, tiges ou produits en verre creux
A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
43.
Glass container comprising a glass bottom with improved properties
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
B65D 1/02 - Bouteilles ou réceptacles similaires, à cols ou à ouvertures rétrécies analogues, conçus pour verser le contenu
B65D 81/30 - Adaptations pour empêcher la détérioration ou l'altération du contenuApplications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux en excluant la lumière ou toute autre radiation extérieure
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
C03B 23/08 - Finition des tubes ou des tiges aux dimensions exactes, p. ex. calibrage
C03B 23/09 - Refaçonnage des extrémités, p. ex. rainures, gorges ou embouchures
C03B 23/11 - Refaçonnage par étirage sans soufflage, en combinaison avec un sectionnement, p. ex. pour fabriquer des ampoules pharmaceutiques
A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
44.
Apparatus for inspecting pharmaceutical containers
An apparatus for inspecting a pharmaceutical cylindrical container made of glass or polymer is provided. The apparatus includes an inspection area, a handling device, and a friction wheel. The handling device has a first holder configured to hold a lateral surface of the pharmaceutical cylindrical container. The first holder includes a first support wheel and a second support wheel. The handling device moves such that the pharmaceutical cylindrical container is transferred from a first transfer position to the inspection area and from the inspection area to a second transfer position. The first holder and/or the friction wheel bring the pharmaceutical cylindrical container into contact with the friction wheel such that the pharmaceutical cylindrical container is rotated around a container longitudinal axis by rotating the first and second support wheels and/or by rotating the friction wheel.
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
B65G 47/91 - Dispositifs pour saisir et déposer les articles ou les matériaux comportant des pinces pneumatiques, p. ex. aspirantes
G01N 21/01 - Dispositions ou appareils pour faciliter la recherche optique
G01N 21/90 - Recherche de la présence de criques, de défauts ou de souillures dans un récipient ou dans son contenu
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
B65G 47/84 - Roues en forme d'étoiles ou dispositifs à courroies ou chaînes sans fin, les roues ou dispositifs étant dotés d'éléments venant en prise avec les objets
45.
Apparatus for inspecting pharmaceutical containers
An apparatus for inspecting a pharmaceutical cylindrical container made of glass or polymer includes a handling device that has a first holder that holds a lateral surface of the pharmaceutical cylindrical container and includes a first support wheel and a second support wheel. The handling device moves such that the pharmaceutical cylindrical container is transferred from a first transfer position to the inspection area and from the inspection area to a second transfer position. The handling device and/or a friction wheel rotate the pharmaceutical cylindrical container around a container longitudinal axis. A first plane is defined through the first rotational axis of the first support wheel and the container longitudinal axis, while a second plane is defined through the second rotational axis of the second support wheel and the container longitudinal axis. The first and second planes intersect at an angle in a range of 45° to less than 120°.
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
B65G 47/91 - Dispositifs pour saisir et déposer les articles ou les matériaux comportant des pinces pneumatiques, p. ex. aspirantes
G01N 21/01 - Dispositions ou appareils pour faciliter la recherche optique
G01N 21/90 - Recherche de la présence de criques, de défauts ou de souillures dans un récipient ou dans son contenu
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
B65G 47/84 - Roues en forme d'étoiles ou dispositifs à courroies ou chaînes sans fin, les roues ou dispositifs étant dotés d'éléments venant en prise avec les objets
A device is provided that accommodates elongate receptacles and charges. The device includes a superior surface, a first positioning device, a detaining device, and either a pusher or a second positioning device. The first positioning device is adapted and arranged to accommodate a pairing of a charge and a corresponding elongate receptacle. The pusher is moveable along a direction towards the superior surface to introduce the charge into the elongate receptacle. The second positioning device accommodates the pusher with the second positioning device and the pusher being moveable along the direction towards the superior surface to introduce the charge into the elongate receptacle. The detaining device limits the extent of movement of the pusher towards the superior surface.
A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue
B67C 3/22 - Mise en bouteilles de liquides ou de semi-liquidesRemplissage des bocaux ou bidons avec des liquides ou semi-liquides en utilisant des appareils de mise en bouteilles ou des appareils analogues Détails
47.
Glass syringe barrels with increased cone breaking forces
A61M 5/315 - PistonsTiges de pistonGuidage, blocage, ou limitation des mouvements de la tigeAccessoires disposés sur la tige pour faciliter le dosage
A61M 5/32 - AiguillesParties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchonAccessoires pour introduire l'aiguille dans le corps ou l'y maintenirDispositifs pour la protection des aiguilles
A charge device is provided that includes a charge barrel having a charge. The charge barrel has an exit aperture and a flexible positioning device at the exit aperture. The charge is located inside the charge barrel. The charge barrel is adapted and arranged so that the charge is able to exit the charge barrel via the exit aperture.
A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
50.
DEAD END CONTAINER AND CONTAINER ASSEMBLY WITH DEAD END CONTAINER
A container for accommodating pharmaceutical compositions, which is installable in a medical device, is provided. The container includes a hollow cylindrical body having an open end and a dead end opposite to the open end. The dead end is closed by a bottom portion. The hollow cylindrical body and the bottom portion are formed integrally and of the same material. The bottom portion transitions into the hollow cylindrical body via a curved heel that is defined by an outer radius ro, an inner radius ri and a thickness dh in a center portion of the curved heel, wherein the following condition is fulfilled: ri+dh−ro>0 mm.
A61M 5/315 - PistonsTiges de pistonGuidage, blocage, ou limitation des mouvements de la tigeAccessoires disposés sur la tige pour faciliter le dosage
51.
Apparatus for injecting a fluid, comprising a needle assembly and a needle retention device for retaining a needle of the needle assembly when attached to the apparatus, and needle retention device
An apparatus for injecting a fluid includes: an injector including a cylindrical container, a coupling portion, and a peripheral section; a needle assembly including a needle and a hub defining a contact area, the coupling portion configured to be coupled with the hub; and a needle retention device including a needle-retainer portion having a finger configured to radially extend over at least a part of the contact area of the hub, a container-contact portion defining a first opening configured to be attached in a form-fitting way onto the peripheral section of the container. When the apparatus is in its operational state, the hub of the needle assembly is coupled to the coupling portion, the container-contact portion is attached to the container, and the finger of the needle-retainer portion extends over the contact area of the hub when the needle retention device is in its retaining position.
2 or less. The plunger is inside the hollow cylindrical body at the open end, is pierceable by a cannula, and is slidable relative to the hollow cylindrical body from the open end towards the closed end.
A61M 5/20 - Seringues automatiques, p. ex. avec tige de piston actionnée automatiquement, avec injection automatique de l'aiguille, à remplissage automatique
53.
Transport packaging for containers and method of unpacking containers
A transport packaging includes a tray formation which is configured to hold a plurality of containers with mutual separation to avoid mutual contact of the containers. The tray formation includes a first tray part having a plurality of pockets configured to receive first ends of the containers and a second tray part removably coupled to the first tray part and having a corresponding plurality of pockets configured to receive second ends of the containers. The first tray part is formed such that, when the second tray part is removed so that the second ends of the containers are free from the pockets of the second tray part, the free second ends of the containers are free to be brought into mutual contact while the first ends of the containers are still received in the pockets of the first tray part.
A retention chuck for glass pipes for machines producing glass containers is provided. The retention chuck has a central supply channel for the glass pipes, a plurality of adjustable clamping jaws arranged at the lower end of the supply channel and so as to be distributed around a centerline of the channel. The spacing of the jaws from the center line of the supply channel is adjustable by an actuation element. A coupling element couples the jaws to the actuation element. Guides guide the adjustment movement of the clamping jaws perpendicularly, radially inwardly relative to the center line.
B23B 31/175 - Mandrins avec mors à action simultanée, qu'ils soient ou non réglables individuellement déplaçables radialement actionnés par des leviers déplacés par une tige de commande coaxiale
C03B 23/045 - Outils ou appareils spécialement adaptés pour la finition de tubes ou de tiges en général, p. ex. tours verriers, pinces
55.
Classification method and system for high-throughput transparent articles
A method for detecting and classifying defects in high-throughput transparent articles such as syringes, vials, cartridges, ampules, and bottles is provided. The method includes the steps of providing a stream of the articles; capturing a first digital image of each of the articles in the stream; inspecting the first digital image for objects; determining parameters of the objects; performing a first classification step to classify the objects into a first defect class and a second defect class; performing a second classification step to classify the objects into a plurality of defect types using at least two second classification models; comparing at least one object parameter of a classified object with a predetermined defect type dependent threshold; classifying the article as defective or non-defective based on the comparing step; and separating defective articles from non-defective articles.
A glass vial including a boron-containing multicomponent glass includes constituents and is partially filled with a pharmaceutical ingredient formulation having a pH in a range from 5 to 9. The glass vial has a total volume of <4.5 mL, a filling level of the glass vial with the formulation is not more than 0.25, and an inner wall of the glass vial has chemical resistance to leaching-out of at least one of the constituents of the multicomponent glass. A ratio of a concentration of a leached-out constituent at a fill volume of 0.5 mL and a concentration of the leached-out constituent at a fill volume of 2 mL is not more than 3 and a ratio between a concentration of the leached-out constituent at a fill volume of 1 mL and the concentration of the leached-out constituent at a fill volume of 2 mL is not more than 2.
C03C 3/091 - Compositions pour la fabrication du verre contenant de la silice avec 40 à 90% en poids de silice contenant du bore contenant de l'aluminium
C03C 23/00 - Autres traitements de surface du verre, autre que sous forme de fibres ou de filaments
C03B 29/02 - Réchauffage des articles de verre pour ramollir ou fondre leurs surfacesPolissage par la chaleurFusion des bords en discontinu
57.
Container which can be prefilled or is prefilled with fluid, as well as a cannula assembly and closure system for a container which can be prefilled or is prefilled with fluid
A pre-Tillable or prefilled container for at least one of storage or application of a fluid includes: a receptacle having a chamber for accommodation of the fluid; a cannula assembly including a cannula and a sealing element, the cannula having an outside channel opening, the cannula assembly being attachable to the receptacle; and a closure cap including a sealing. The channel opening of the cannula protrudes into the sealing of the closure cap thus sealing the channel opening. Due to at least one of a radial compression or an axial compression of the sealing element, as well as due to sealing of the channel opening by the closure cap, the chamber is sealed in a fluid-tight manner.
A61M 5/32 - AiguillesParties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchonAccessoires pour introduire l'aiguille dans le corps ou l'y maintenirDispositifs pour la protection des aiguilles
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
A61K 38/48 - Hydrolases (3) agissant sur des liaisons peptidiques (3.4)
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
A61M 5/28 - Ampoules ou cartouches-seringues, c.-à-d. ampoules ou cartouches munies d'une aiguille
A61M 5/34 - Structures pour le raccordement de l'aiguille
A positioning device for a preloading ring of a hot forming machine is provided. The device has a first holding element and a second holding element. The first holding element has a first recess and a second recess. The second recess is at a distance radially with respect the first recess. The second holding element is arranged in a region of and faces the first and second recess. The first and second holding elements are configured and arranged movably about respective axes with respect to each other so that movement towards each other encloses a glass tube in each of the first and second recesses and between the holding elements.
A method and device for the continuous heat treatment of pharmaceutical glass containers are provided. The method includes continuously conveying glass containers from an entry region to an exit region via a conveying installation having a separating plate made from an electrically conductive material, the separating plate being positioned above and/or below the conveying installation; heating the glass containers to a maximum temperature in a heating zone after passing the entry region; cooling the glass containers in a first cooling zone after passing the heating zone and before passing the exit region at a first cooling rate, wherein the separating plate separates the glass containers from heating installations in the heating zone and/or temperature changing installations in the first cooling zone; and controlling the heating installations and/or the temperature changing installations to inductively heat the separating plate in the heating zone and/or the first cooling zone.
A hot forming device for producing glass containers from a glass tube is provided. The device includes a machine frame, a turntable, a plurality of holding chucks, and a direct drive motor. The turntable is mounted on the machine frame. The holding chucks are arranged on the turntable. The turntable is connected to the machine frame directly by the direct drive without a transmission. The direct drive has a stator arranged in an upper region of the machine frame and a rotor on the turntable.
A hot-forming device is provided for producing glass containers from a glass tube. The device includes a rotary table mounted so as to be rotationally movable and an assigned drive motor for driving the rotary table. The rotary table includes several holding chucks for holding workpieces distributed around the circumference of the rotary table. The rotary table has a coolant channel that is fluid-tight and through which a coolant can flow to cool.
A method for molding end portions on glass containers that store pharmaceutical active ingredients is provided. The glass containers are produced from a glass tube by hot-forming, an end portion having a neck opening using a centrally disposed opening forming tool interacting with a shaping tool at one end of the glass containers. In the method, dimensional data is provided for the respective glass tube and the position of the shaping tool is adjusted in a motorized manner in the axial direction (z) of the glass containers so as to correspond to the provided dimensional data for the respective glass tube.
A process for producing a glass article is provided that includes, in order, a first process step in which a surface of the glass article has a temperature of at least 400° C. for at least some of the time, a second process step in which the surface of the glass article has a temperature of more than 10° C. and less than 100° C. and the surface is brought into contact with water or water vapor and the surface of the glass article is supplied with an amount of water which corresponds to a water layer thickness of from 1 to 100 μm, and a third process step in which the glass article is processed further with contact of the surface with foreign materials or other glass articles.
A syringe body for a syringe for injecting a highly viscous medium has a hollow cylindrical configuration, forms a chamber configured to receive the highly viscous medium, and includes: a distal end portion; a proximal end portion having an opening through which a piston rod arrangement is insertable into the chamber; and a Luer lock connector formed at the distal end portion, the Luer lock connector having an outer cone with a further opening configured to dispense the highly viscous medium and a sleeve-shaped portion with an inner thread. The syringe body has a minimum NPO resistance of over 90 N.
A61M 5/32 - AiguillesParties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchonAccessoires pour introduire l'aiguille dans le corps ou l'y maintenirDispositifs pour la protection des aiguilles
66.
Holding structure for simultaneously holding a plurality of containers for substances for pharmaceutical, medical or cosmetic applications, transport unit and transport or packaging container having the same
The present invention relates to a holding structure for simultaneously holding a plurality of containers for substances for pharmaceutical, medical or cosmetic applications or of devices having such containers, having a plurality of receptacles. The receptacles are arranged in a regular arrangement and are formed by in each case peripherally formed side walls. The receptacles have in each case one or two widened clearances having a dimension which is greater than the width of a gap between the containers received in the receptacles and side walls of the receptacles in the regions other than the widened clearances. The widened clearances additionally make available space for access to containers or devices which are received in the receptacles for handling thereof.
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
B65D 1/36 - Plateaux ou réceptacles analogues peu profonds avec compartiments ou cases moulées
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
B65D 25/10 - Dispositifs pour placer les objets dans les réceptacles
67.
Holding structure with a plurality of containers held thereon for substances for pharmaceutical, medical or cosmetic applications, and transport or packaging container having same
A combination includes: a holding structure including receptacles which are arranged in a regular arrangement and are formed by peripherally formed side walls; containers received in the receptacles, the containers having a basic body which, at an upper end, merges into a shoulder portion which is adjoined by a narrowed neck portion with a widened upper edge with an opening; holding projections provided at lower ends of the receptacles and configured to hold the containers in the receptacles, the holding projections at the lower ends protruding radially inwards into the receptacles, the containers being supported directly on the holding projections; and centering elements provided above the holding projections and configured to center the containers in the receptacles. The centering elements have a beveled configuration and protruding into the receptacles in order to reduce a width of the receptacles at the lower ends thereof in a funnel shape.
A hot-forming tool for producing glass containers is provided. The tool includes a forming roller, a holder, and a heat sink. The forming roller has a forming surface. The holder receives the forming roller with the forming roller rotatably mounted on the holder. The heat sink is directly or indirectly connected to the holder. The forming roller is in thermal contact with the heat sink and the heat sink has an internal cooler so that process heat can be transferred from the forming roller to the heat sink.
A method of treating a glass cylinder for a piston-cylinder arrangement for reducing the friction of a piston on an inner cylinder wall of the glass cylinder includes: elevating surface energy of glass of an interior bounded by the inner cylinder wall and hence lowering a contact angle of the glass with water. The contact angle is lowered by: a gas discharge that acts on the glass at the inner cylinder wall and is generated by an electric or electromagnetic field; or the action of ozone on the glass surface. The glass with the lowered contact angle is contacted with water to form a water film on the contacted glass.
C03C 23/00 - Autres traitements de surface du verre, autre que sous forme de fibres ou de filaments
70.
Transport unit and packaging structure for transporting and storing a plurality of containers for substances for pharmaceutical, medical or cosmetic uses
A transport unit for a packaging structure for a plurality of containers for substances for pharmaceutical, medical or cosmetic uses includes a tray with a plurality of seats for positioning the containers and a planar inlay part for covering the containers positioned in the seats of the tray. The inlay part is configured to cover the containers positioned in the seats and at the same time to be received completely in the tray, without protruding above an upper edge of the tray. A plurality of depressions corresponding to the seats of the tray are formed in the inlay part, in order to position the containers at their two ends lying opposite each other. A gap is formed at least partially between the inlay part, received in the tray, and side walls of the tray.
An apparatus for producing a glass workpiece includes: a device configured to heat a glass until it softens; an inner molding tool configured to mold inner lateral surfaces of the workpiece; an outer molding tool configured to mold outer lateral surfaces of the workpiece, the outer molding tool having a shaping roller with a shaping surface; an accommodating device configured to accommodate the shaping roller, the shaping roller being mounted in a freely rotatable manner in the accommodating device and is fixable during a shaping process by a lockable locking device, the shaping roller being locked with a releasable connection such that the shaping roller can be released and rotated through an angle α in the locking device between individual shaping processes; and an apparatus configured to apply a lubricating oil to the shaping surface of the shaping roller and having an outlet opening configured to dispense the lubricating oil.
C03B 9/193 - Soufflage du verreProduction d'articles de verre creux soufflés dans des machines alimentées en paraisons dans des machines du type "pressé-soufflé"
C03B 13/18 - Appareillage auxiliaire pour le laminage du verre, p. ex. supports de feuilles, dispositifs de préhension, poches, moyens pour déplacer les pots
A syringe body for a pharmaceutical syringe is provided. The syringe includes cylindrical cavity, a finger flange, and an anti-slip element. The cylindrical cavity has a first end face with a cone and a second, open end face configured to receive a piston. The finger flange is arranged around a circumference of the second, open end face. The finger flange has a first surface that faces the cone. The anti-slip element is a roughened area on the first surface. The roughened area exhibits an arithmetic mean roughness value between 0.8 μm and 150 μm.
A primary packaging container for pharmaceuticals is provided. The container includes a hollow body, an opening, and a closure. The hollow body has an opening and is made of a cycloolefin polymer or a cycloolefin copolymer. The closure has a puncture region. The closure closes the opening with the puncturing region at the opening. The puncturing region is configured to allow introduction of a cannula into the hollow body and resealing the hollow body upon withdraw of the cannula. The closure has an elastomer that is connected to the hollow body so as to be not separable in a non-destructive manner.
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
C08L 23/02 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères non modifiées par un post-traitement chimique
A syringe includes a syringe body, which has a cylindrical portion and, adjoining the latter, a frustoconical portion, and a Luer lock connector, which has a Luer collar with an inner thread and a Luer cone with a through-channel. A bottom surface is formed between the Luer collar and Luer cone. The syringe body and the Luer lock connector are formed in one piece and are made of a cyclic olefin resin. The Luer collar has reinforcing ribs on its outer face.
A method for controlling a rotary drive of a hot forming machine having a plurality of processing stations arranged in a circular manner and a rotary table arranged thereabove, in which glass tubes to be processed are held and moved from one processing station to the next by a stepwise rotary movement, is provided. The rotary table is driven by a step gear by which a movement of a drive shaft is translated into a cyclic step movement, a step cycle of which comprises a movement phase and a subsequent standstill phase. A first value for the angular velocity of the drive shaft is assumed at a first time in the movement phase of the step cycle and a second value different from the first value is assumed at a second time in the standstill phase of the same step cycle.
C03B 23/045 - Outils ou appareils spécialement adaptés pour la finition de tubes ou de tiges en général, p. ex. tours verriers, pinces
F16H 27/04 - Mécanismes pas à pas sans organes à roue libre, p. ex. entraînements à croix de Malte pour convertir un mouvement de rotation continu en un mouvement rotatif pas à pas
C03B 23/11 - Refaçonnage par étirage sans soufflage, en combinaison avec un sectionnement, p. ex. pour fabriquer des ampoules pharmaceutiques
C03B 23/043 - Dispositifs de chauffage spécialement adaptés pour la finition de tubes ou de tiges en général, p. ex. brûleurs
76.
CLOSURE PIECE FOR A CONTAINER FOR PHARMACEUTICAL PREPARATIONS, AND CONTAINER PROVIDED WITH THIS CLOSURE PIECE
A closure piece is provided for the releasable closure of an opening at the distal end of a cylindrical container for pharmaceutical preparations. The container may be a syringe with a Luer lock fastening. The closure piece includes a cylindrical closure cap, with a cylindrical cavity for receiving and retaining a sealing element, and a sealing element. The sealing element has a rearward offset in relation to an outer edge of the closure cap.
B65B 7/28 - Fermeture de réceptacles ou récipients semi-rigides ou rigides, non déformés par le contenu ou n'en prenant pas la forme, p. ex. boîtes ou cartons en appliquant des fermetures séparées préformées, p. ex. couvercles, capuchons
B29C 45/00 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
77.
Holding structure for concurrently holding a plurality of containers for substances for pharmaceutical, medical or cosmetic applications, transport structure and transport or packaging container comprising the same
A holding structure for concurrently holding a plurality of containers for substances for pharmaceutical, medical or cosmetic applications includes a plurality of receptacles for receiving the containers therein at least in sections. The receptacles each have an open upper end for inserting the containers into the receptacles and a bottom end having a holding portion for limiting an axial movement of the containers in the receptacles. Guide portions are provided for guiding the containers as they are inserted into the receptacles. The guide portions are formed as guiding ribs extending in the longitudinal direction of the receptacles. Lead-in bevels are formed at upper ends of the guiding ribs which are inclined relative to the guiding ribs.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
78.
Holding structure for holding a plurality of containers for pharmaceutical, medical or cosmetic purposes and transport or packaging container comprising the same
A holding structure for holding a plurality of containers for pharmaceutical, medical or cosmetic purposes includes a carrier having openings or receptacles for accommodating the containers. Holding devices for holding the containers are provided at the openings or receptacles. The holding devices can selectively assume two different stable positions, namely a first stable position in which the containers can be inserted without friction into the openings or receptacles and a second stable position in which the containers are held in the respective opening or receptacle by frictional engagement or by positive locking. The containers can be reliably inserted into the openings or receptacles without material abrasion. In the open insertion position of the holding devices, a large number of containers can be inserted concurrently into the openings or receptacles without high forces acting on the holding structure.
B65D 71/62 - Éléments d'emballage de type plateau munis de poignées pour le stockage ou le transport de plusieurs objets formés en pliant un flan en élément tubulaire dont les portions de parois supérieures sont munies d'ouvertures à travers lesquelles dépassent les objets avec des parties de parois repliées l'une contre l'autre pour former un cloisonnement longitudinal entre deux rangées d'objets
B65D 25/10 - Dispositifs pour placer les objets dans les réceptacles
B65D 71/64 - Éléments d'emballage de type plateau munis de poignées pour le stockage ou le transport de plusieurs objets formés en pliant un flan en élément tubulaire dont les portions de parois supérieures sont munies d'ouvertures à travers lesquelles dépassent les objets avec des parois entourant les objets presque entièrement
B65D 1/34 - Plateaux ou réceptacles analogues peu profonds
B65D 81/38 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu avec isolation thermique
B01L 9/00 - Dispositifs de supportDispositifs de serrage
B65D 5/50 - Éléments internes de support ou de protection du contenu
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
A device for the shaping of glass bodies, in particular of pharmaceutical vials, comprises a clamping chuck for holding a glass body, a rotary drive for driving the clamping chuck rotatingly, further at least one heat source for heating a glass body held within the clamping chuck, and further a controller which is coupled to the rotary drive so that the clamping chuck can be driven at variable rotational speed.
The present disclosure provides a tube catcher for a hot forming machine comprising a foot for mounting the tube catcher in the hot forming machine, an upper contact surface for catching a glass tube as it falls into the hot forming machine, and a damping element, which is arranged below the upper contact surface in such a way that it allows the upper contact surface to elastically recede in the direction of the falling direction of the glass tube. This minimizes damage to glass tubes on impact and permits a high production speed. For this purpose, the damping element includes a compressible chamber that can be filled with a gas.
F16F 9/04 - Ressorts, amortisseurs de vibrations, amortisseurs de chocs ou amortisseurs de mouvement de structure similaire, utilisant un fluide ou moyen équivalent comme agent d'amortissement utilisant un gaz uniquement dans une chambre à paroi flexible
C03B 23/11 - Refaçonnage par étirage sans soufflage, en combinaison avec un sectionnement, p. ex. pour fabriquer des ampoules pharmaceutiques
C03B 23/045 - Outils ou appareils spécialement adaptés pour la finition de tubes ou de tiges en général, p. ex. tours verriers, pinces
B65G 29/00 - Transporteurs rotatifs, p. ex. disques, bras, croisillons ou cônes rotatifs
C03B 35/04 - Transport des articles de verre creux chaud
81.
Method and device for optical examination of transparent bodies
A method and a device for optical examination of transparent bodies made of plastic, glass, or glass ceramic are provided. The examination is carried out by contactless detection and measurement of the body using optical imaging devices. For this purpose, a plurality of individual images are taken of the body during the examination in different positions relative to the imaging device, which are subsequently analyzed.
A transport structure for accommodating a plurality of vials for pharmaceutical, medical or cosmetic use under non-sterile conditions is formed by an accommodation member and by a bearing member releasably connected thereto. The accommodation member comprises a plurality of frustro-conical receptacles in a regular arrangement so that the vials can be accommodated upright and while preventing a direct contact between adjacent vials in the receptacles of the accommodation member. The transport structure comprises latching structures for releasable latching of the accommodation member with the bearing member. According to the disclosure, the receptacles are matched to the height of the vials in such a manner that the vials can be completely accommodated therein, wherein the bearing member is formed by a base plate having a flat supporting surface facing the receptacles, so that the vials can be freely displaced on the supporting surface of the base plate after releasing the latching and can be pushed from the bearing member by displacement of the accommodation member relative to the bearing member. The accommodation member and/or the bearing member can be formed in one piece by thermoforming a plastic material, in particular by deep-drawing a thin film or a thin film plate.
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
83.
Supporting structure for concurrently supporting a plurality of containers for substances for pharmaceutical, medical or cosmetic applications, transport structure and transport or packaging container comprising the same
The present disclosure relates to a supporting structure for concurrently supporting a plurality of containers for substances for pharmaceutical, medical or cosmetic applications, having a plurality of receptacles for accommodating the containers therein at least partially. Each of the receptacles has an open upper end for inserting the containers into the receptacles and a lower end having a retaining portion for delimiting an axial movement of the containers in the receptacles. Guiding portions are provided for guiding the containers into the receptacles during insertion. The guiding portions can have upper guiding and positioning portions close to the upper ends of the receptacles and lower guiding and positioning portions close to the lower ends of the receptacles, which are formed separately from each other and delimit a radial movement of the containers in the receptacles.
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
B65B 3/00 - Emballage de matériaux plastiques, de semi-liquides, de liquides ou de liquides et solides mélangés, dans des réceptacles ou récipients individuels, p. ex. dans des sacs ou sachets, boîtes, cartons, bidons ou pots
B65D 1/36 - Plateaux ou réceptacles analogues peu profonds avec compartiments ou cases moulées
B65D 25/10 - Dispositifs pour placer les objets dans les réceptacles
B65B 7/28 - Fermeture de réceptacles ou récipients semi-rigides ou rigides, non déformés par le contenu ou n'en prenant pas la forme, p. ex. boîtes ou cartons en appliquant des fermetures séparées préformées, p. ex. couvercles, capuchons
B65B 21/18 - Introduction ou enlèvement de groupes de bouteilles pour remplir ou vider les réceptacles en une seule opération en utilisant des pinces prenant les bouteilles, p. ex. par le goulot
B65B 43/56 - Moyens pour tenir les réceptacles ou les récipients pendant le remplissage avec déplacement par positions successives pour présenter le réceptacle ou récipient en vue de recevoir des apports successifs du contenu
A carrier rack for pharmaceutical containers or medical packaging products having a non-cylindrical symmetric flange. The carrier rack includes a plurality of through-openings defined by the carrier rack for accommodating the pharmaceutical containers or medical packaging products, and at least one member protruding above a top side of the carrier rack and having a height. Each member includes at least one of at least one bevel and at least one radius, wherein the at least one member is allocated to each one of the plurality of through-openings, and wherein at least one of the at least one bevel and the at least one radius interact with the non-cylindrical symmetric flange in such a way that the pharmaceutical containers or medical packaging products are aligned.
B65D 25/10 - Dispositifs pour placer les objets dans les réceptacles
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
B65D 69/00 - Objets groupés pour commodité de stockage ou de transport sans utiliser d'éléments d'emballage
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
85.
Tungsten containing forming mandrel for glass forming
A molding tool, a method, and an apparatus for hot forming of glass are provided that provide glass products used for pharmaceutical packaging. The molding tool includes a forming mandrel for reshaping at least a portion of a heated region of a glass precursor. The mandrel has a temperature-stable core material and an alloying element. The core material is made of precious metals, in particular of platinum group elements, and the further alloying element is made of one of tungsten, zirconium, rhodium, molybdenum, and rhenium.
C03B 23/045 - Outils ou appareils spécialement adaptés pour la finition de tubes ou de tiges en général, p. ex. tours verriers, pinces
C03B 23/055 - Finition des tubes ou des tiges par laminage
C22C 5/04 - Alliages à base d'un métal du groupe du platine
C03B 23/09 - Refaçonnage des extrémités, p. ex. rainures, gorges ou embouchures
C03B 23/043 - Dispositifs de chauffage spécialement adaptés pour la finition de tubes ou de tiges en général, p. ex. brûleurs
C03B 23/049 - Finition des tubes ou des tiges par pressage
86.
Medical packaging material, in particular pharmaceutical packaging material as well as methods of joining plastic components of medical packaging materials
A medical packaging material, in particular a pharmaceutical packaging material, comprising a first thermoplastic plastic component body consisting of a first material, a second thermoplastic plastic component body consisting of a second material, wherein between the first plastic component body and the second plastic component body at least one internal interface having a scattering effect is arranged that results preferably in an extended wavelength of radiated light.
B32B 27/08 - Produits stratifiés composés essentiellement de résine synthétique comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique d'une résine synthétique d'une sorte différente
B23B 27/20 - Outils de coupe sur lesquels les taillants ou éléments tranchants sont en matériaux particulier à éléments tranchants constitués par des diamants
B32B 27/20 - Produits stratifiés composés essentiellement de résine synthétique caractérisée par l'emploi d'additifs particuliers utilisant des charges, des pigments, des agents thixotropiques
B29C 65/00 - Assemblage d'éléments préformésAppareils à cet effet
A device for the shaping of glass bodies, in particular of pharmaceutical vials, comprises a clamping chuck for holding a glass body, a rotary drive for driving the clamping chuck rotatingly, further at least one heat source for heating a glass body held within the clamping chuck, and further a controller which is coupled to the rotary drive so that the clamping chuck can be driven at variable rotational speed.
A syringe having a finger flange and a finger support is provided. The finger flange includes a radially projecting support surface for a finger and is joined to the syringe body of the syringe at its proximal end. In this case, the finger flange is further designed in one piece and includes at least two finger flange elements, which are movably joined with one another.
A container for storing and/or applying a substance is provided. The container includes a glass body having a substantially hollow cylindrical shape and enclosing a cavity, as well as a distal end with a first opening and a proximal end with a second opening. One or more connecting elements are attached to the glass body at the distal end and are made of a plastic material. The plastic material is a thermoplastic or thermosetting plastic material and the glass body and the or each connecting element are connected to each other by use of a joint. The connecting element arranged at the distal end includes a passage channel communicating with the first opening. The first and second openings are enclosed by end faces and immediately adjacent surfaces of the glass body and the connecting element(s) is/are attached to the glass body via the end faces and the immediately adjacent surfaces.
A carrier plate for pharmaceutical containers, in particular syringes bottles, or ampoules, includes a receiving region that has a plurality of through-openings for receiving the pharmaceutical containers. The receiving region includes a handling region that defines a base plane for handling the carrier plate, in particular for engaging on the carrier plate and/or for supporting same, having a top face that functions as a pressure side under a load and a lower face that functions as a tension side. A structural member for increasing the rigidity of the carrier plate is also provided that includes at least one box profiled region between at least two through-openings on the upper face of the carrier plate.
The invention relates to a syringe cap (1) for a medical syringe (28), having two cap parts (2, 3) displaceable toward each other, wherein a motion of the cap parts (2, 3) toward each other takes place when the syringe cap (1) is first removed from the syringe (28). In order to disclose a syringe cap for a medical syringe, wherein a first use can be advantageously determined and handling is simple, according to the invention an indicator element is displaced into a display setting and the display element (6) can be removed from the syringe (28) together with the cap parts (2, 3) of the syringe cap (1).
A61M 5/50 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras avec des moyens pour empêcher la réutilisation ou pour indiquer si le dispositif est défectueux, usagé, non stérile ou si l'on a tenté de l'utiliser
A61M 39/04 - Voies d'accès avec des éléments perforables auto-obturants
A container for pharmaceutical and medical applications made from glass, preferably from a borosilicate glass. The container is formed in the shape of a hollow body open at both its ends with a cylindrical portion having a wall thickness tolerance of maximally ±0.2 mm. The borosilicate glass has a nominal boron content that drops by less than 40% relative to the nominal value at all of the surfaces of the container.
A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
C03B 9/193 - Soufflage du verreProduction d'articles de verre creux soufflés dans des machines alimentées en paraisons dans des machines du type "pressé-soufflé"
A61J 1/00 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques
93.
Borosilicate glass syringe with cone coating that increases surface roughness
The invention proposes a process for the production of a container made from glass, in the form of a hollow body open on both ends for pharmaceutical and medical applications, in particular in the form of a syringe barrel, where a glass drop (14) is dispensed from a melting unit, is placed into a mold (12) that is driven to rotate, and is formed by the effect of the centrifugal force, the mold being driven at a rotational speed of at least 5000 rpm, preferably approximately 50000 rpm.
A47G 19/22 - Récipients à boissons ou soucoupes utilisés dans le service de table
B28B 11/00 - Appareillages ou procédés pour le traitement ou le travail des objets façonnés
B28B 21/00 - Procédés ou machines spécialement adaptés à la fabrication des objets de forme tubulaire
B28B 21/72 - Fabrication de tubes à plusieurs coudes
B28B 23/08 - Aménagements spécialement adaptés à la fabrication d'objets façonnés avec des éléments complètement ou partiellement enrobés dans le matériau de moulage dans lesquels les éléments enrobés sont des renforcements les éléments enrobés étant sous tension pour la fabrication d'objets de forme allongée de forme tubulaire
The invention proposes a process for the production of a container for pharmaceutical and medical applications made from glass, preferably from a borosilicate glass, wherein the container is produced by a press-blow process where the container is initially preformed in a pressing step, by making a ram press a dispensed glass drop into a mold that is open at its bottom, and where the parison so produced is given its final form by a subsequent blowing step.
C03B 9/193 - Soufflage du verreProduction d'articles de verre creux soufflés dans des machines alimentées en paraisons dans des machines du type "pressé-soufflé"
brevets
