The First Affiliated Hospital of Jinan University

Chine

Retour au propriétaire
1-2 de 2 pour The First Affiliated Hospital of Jinan University Trier par
Recheche Texte
Affiner par
Juridiction
        Canada 1
        International 1
Classe IPC
A61P 31/10 - Antifongiques 2
C07D 295/194 - Radicaux dérivés d'acides thio- ou thiono carboxyliques 2
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine 1
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier 1
Statut
En Instance 1
Enregistré / En vigueur 1
Résultats pour  brevets

1.

APPLICATION OF POLYCYCLIC AROMATIC COMPOUND IN THE PREPARATION OF ANTIFUNGAL DRUGS

      
Numéro de document 03224558
Statut En instance
Date de dépôt 2022-05-24
Date de disponibilité au public 2023-01-19
Propriétaire THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Hong
  • Ye, Wencai
  • Zhang, Yishan
  • Hu, Lijun
  • Li, Shuixiu
  • Zhao, Yajing
  • Tang, Chuanyan
  • Weng, Luobang

Abrégé

The present invention provides a polycyclic aryl compound S1 for preparing a drug for antifungal infection. The structural formula of the polycyclic compound is S1. The polycyclic aryl compound having the shell-core structure and represented by S1 in the present invention is suitable for preparing drugs for anti-Candida, Aspergillus, Mucor and other pathogenic fungal infections, and has the following beneficial effects: the compound S1 of the present application has a broad-spectrum antifungal effect on pathogenic fungi including, but not limited to, Candida, Aspergillus, Mucor, etc., is effective against azole resistant Candida, is low in toxicity to mammals, and can treat systemic fungal infection by oral administration, and can also be used locally to treat mucosal Candida infection.

Classes IPC  ?

2.

APPLICATION OF POLYCYCLIC ARYL COMPOUND IN PREPARATION OF ANTIFUNGAL DRUG

      
Numéro d'application CN2022094745
Numéro de publication 2023/284420
Statut Délivré - en vigueur
Date de dépôt 2022-05-24
Date de publication 2023-01-19
Propriétaire THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Hong
  • Ye, Wencai
  • Zhang, Yishan
  • Hu, Lijun
  • Li, Shuixiu
  • Zhao, Yajing
  • Tang, Chuanyan
  • Weng, Luobang

Abrégé

The present invention provides a polycyclic aryl compound S1 for preparing a drug for antifungal infection. The structural formula of the polycyclic compound is S1. The polycyclic aryl compound having the shell-core structure and represented by S1 in the present invention is suitable for preparing drugs for anti-Candida, Aspergillus, Mucor and other pathogenic fungal infections, and has the following beneficial effects: the compound S1 of the present application has a broad-spectrum antifungal effect on pathogenic fungi including, but not limited to, Candida, Aspergillus, Mucor, etc., is effective against azole resistant Candida, is low in toxicity to mammals, and can treat systemic fungal infection by oral administration, and can also be used locally to treat mucosal Candida infection.

Classes IPC  ?

  • C07D 295/194 - Radicaux dérivés d'acides thio- ou thiono carboxyliques
  • A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
  • A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
  • A61P 31/10 - Antifongiques