05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Procedural controls in the nature of chemical reagents for medical and veterinary purposes, namely, stable white blood cell reference control for use in immunophenotyping by flow cytometry
3.
METHOD FOR SPRAY COATING A SURFACE ATTACHED HYDROGEL
A coated container having reduced nonspecific adsorption of nonspecific targets can have an interior volume surrounded by one or more walls having one or more interior surfaces, and a coating comprising a spray-coated hydrogel layer surface attached to the one or more interior surfaces, the spray-coated hydrogel having surface roughness with surface features with an average features height of less than 20 nm.
C03C 17/00 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement
A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
C03C 17/32 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des matières organiques avec des résines synthétiques ou naturelles
Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple β-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of β-lactamase genes selected from the group consisting of one or more of the following: MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51 -like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, SHV-like, and GES-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
5.
COMPOSITIONS AND USES THEREOF FOR STABILIZATION OF BLOOD SAMPLE COMPONENTS
A61K 31/554 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. clothiapine, diltiazem
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
6.
COMPOSITIONS AND USES THEREOF FOR STABILIZATION OF BLOOD SAMPLE COMPONENTS
Provided herein are compositions comprising (1) a citrate-based anticoagulant (AC), an aldehyde releaser (AR), a calcium channel blocker, and a sodium channel blocker and (2) a citrate-based anticoagulant (AC), an aldehyde releaser (AR), and a sodium channel blocker, and uses of such compositions for stabilizing components in a blood sample.
A61K 31/554 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. clothiapine, diltiazem
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
7.
METHODS OF PREPARING SAMPLES FOR PROTEOMIC ANALYSIS
Provided herein are methods of preparing a protein sample for proteomic analysis. In exemplary embodiments, the method comprises (a) contacting a blood sample comprising proteins with a protective agent comprising an anticoagulant (AC) and an aldehyde releaser (AR), to obtain a mixture, optionally, wherein the blood sample is added to a blood collection tube (BCT) comprising the protective agent, and (b) isolating a fraction comprising proteins or a source of proteins from the mixture to yield a protein sample or a source of a protein sample, wherein steps of the method are carried out in the absence of exogenous proteolytic enzyme inhibitors, wherein the protein sample is suitable for proteomic and peptidomedic analysis.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
C09K 15/20 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'azote et de l'oxygène
9.
Assays and methods for determining microbial resistance
Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple β-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of β-lactamase genes selected from the group consisting of one or more of the following: MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51-like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
C12Q 1/6809 - Méthodes de détermination ou d’identification des acides nucléiques faisant intervenir la détection différentielle
C12Q 1/6837 - Couplage enzymatique ou biochimique d’acides nucléiques à une phase solide utilisant des réseaux de sondes ou des puces à sondes
Methods and devices for stabilizing a biological sample for analysis, comprising the steps of obtaining in a sample collection device a biological sample from a subject, the biological sample including at least one circulating cell-free first nucleic acid from the subject. The methods may include a step of contacting the biological sample while within the sample collection device with a protective agent composition that includes a preservative agent, an optional anticoagulant, and a quenching agent to form a mixture that includes the protective agent composition and the sample.
A suspension composition for a hematology analysis control particularly useful for preserving relevant detectable characteristics of blood cells for a prolong stability period. The suspension may include at least one polysaccharide, which may include or derive from chitosan and/or chitin, as a stabilizing agent.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
C12N 5/078 - Cellules du sang ou du système immunitaire
13.
Compositions and methods for stabilizing circulating tumor cells
Compositions and Methods for Stabilizing Circulating Tumor Cells Methods and compositions for stabilizing a biological sample for analysis, comprising the steps of obtaining in a sample collection device a biological sample from a subject, especially blood, the biological sample including at least one circulating tumor cell from the subject. The methods may include a step of contacting the biological sample with a protective agent composition that includes a preservative agent, an optional anticoagulant, and a quenching agent to form a mixture that includes the protective agent composition and the sample.
An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate detection of stationary samples, reduced sample read time, and simultaneous reading of multiple light wavelengths.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Calibration, reference, and quality control fluids for
molecular instrumentation used in scientific and research
laboratories; calibration, reference, and quality control
fluids for molecular instrumentation used in clinical
laboratories.
A composition and method for preserving a urine sample and a preservative delivery vessel are disclosed wherein treatment of the urine sample aids in preserving circulating cell-free nucleic acids in urine over a wide range of dilution ratios within temperature fluctuations that can occur during urine sample handling, storage and transportation. The urine sample preservation composition and method and preservative delivery vessel provide a method for obtaining high quality stabilized urinary cell-free nucleic acids for clinical diagnostics development and application.
A composition and method of use thereof wherein the composition comprises one or more components capable of releasing an aldehyde, one or more anticoagulants or chelating agents, and one or more polysaccharides. The composition has a pH of from about 4 to about 6.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Calibration, reference, and quality control fluids for molecular instrumentation used in scientific and research laboratories; Calibration, reference, and quality control fluids for molecular instrumentation used in clinical laboratories
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Cell stabilization diagnostic reagents for medical-scientific research use.
(2) General medical use reagents for preserving cells in a liquid medium
Compositions and Methods for Stabilizing Circulating Tumor Cells Methods and compositions for stabilizing a biological sample for analysis, comprising the steps of obtaining in a sample collection device a biological sample from a subject, especially blood, the biological sample including at least one circulating tumor cell from the subject. The methods may include a step of contacting the biological sample with a protective agent composition that includes a preservative agent, an optional anticoagulant, and a quenching agent to form a mixture that includes the protective agent composition and the sample.
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
C09K 15/20 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'azote et de l'oxygène
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
In vitro diagnostic reagent, for clinical, medical, or research laboratory purposes, used as a control for evaluating accuracy and precision of hematology testing In vitro diagnostic reagent, for medical purposes, used as a control for evaluating accuracy and precision of hematology testing
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Custom manufacturing services for others in the field of
quality control and diagnostic laboratory equipment for
clinical and research use in the fields of hematology,
immunology, molecular diagnostics, infectious diseases and
urinalysis; custom manufacture of quality control and
diagnostic laboratory equipment to the order and
specification of others for clinical and research use in the
fields of hematology, immunology, molecular diagnostics,
infectious diseases and urinalysis. Development of quality control and diagnostic products for
others, namely laboratory equipment, for clinical and
research use in the fields of hematology, immunology,
molecular diagnostics, infectious diseases and urinalysis;
development of quality control and diagnostic products,
namely, laboratory equipment, for clinical and research use
to the order and specification of others in the fields of
hematology, immunology, molecular diagnostics, infectious
diseases and urinalysis; inter-laboratory quality control
services for others; hematology and molecular analysis for
scientific research purposes.
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Custom manufacturing services for others in the field of quality control and diagnostic laboratory equipment for clinical and research use in the fields of hematology, immunology, molecular diagnostics, infectious diseases and urinalysis; custom manufacture of quality control and diagnostic laboratory equipment to the order and specification of others for clinical and research use in the fields of hematology, immunology, molecular diagnostics, infectious diseases and urinalysis.
(2) Development of quality control and diagnostic products for others, namely laboratory equipment, for clinical and research use in the fields of hematology, immunology, molecular diagnostics, infectious diseases and urinalysis; development of quality control and diagnostic products, namely, laboratory equipment, for clinical and research use to the order and specification of others in the fields of hematology, immunology, molecular diagnostics, infectious diseases and urinalysis; providing quality control services for others in the field of laboratory testing and performance evaluation; hematology and molecular analysis, in the nature of blood analysis for scientific research purposes.
34.
Assays and methods for determining microbial resistance
Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple β-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of β-lactamase genes selected from the group consisting of one or more of the following: MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51-like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
C12Q 1/6809 - Méthodes de détermination ou d’identification des acides nucléiques faisant intervenir la détection différentielle
C12Q 1/6837 - Couplage enzymatique ou biochimique d’acides nucléiques à une phase solide utilisant des réseaux de sondes ou des puces à sondes
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
C09K 15/20 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'azote et de l'oxygène
36.
Suspension composition for hematology analysis control
A suspension composition for a hematology analysis control particularly useful for preserving relevant detectable characteristics of blood cells for a prolong stability period. The suspension may include at least one polysaccharide, which may include or derive from chitosan and/or chitin, as a stabilizing agent.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
C12N 5/078 - Cellules du sang ou du système immunitaire
Reference controls for use in downstream molecular technologies comprising a control composition including a sample base matrix, such as at least one biological fluid or biological fluid component, at least one condition component processed to be indicative of a condition, and at least one cross-linking agent.
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Manufacturing services for others in the field of quality control and diagnostic laboratory equipment for clinical and research use in the fields of hematology, immunology, molecular diagnostics, infectious diseases and urinalysis; Custom manufacture of quality control and diagnostic laboratory equipment to the order and specification of others for clinical and research use in the fields of hematology, immunology, molecular diagnostics, infectious diseases and urinalysis Development of quality control and diagnostic products for others, namely, laboratory equipment, for clinical and research use in the fields of hematology, immunology, molecular diagnostics, infectious diseases and urinalysis. Development of quality control and diagnostic products, namely, laboratory equipment, for clinical and research use to the order and specification of others in the fields of hematology, immunology, molecular diagnostics, infectious diseases and urinalysis; interlaboratory quality control services for others; hematology and molecular analysis for scientific research purposes
39.
Single spin process for blood plasma separation and plasma composition including preservative
A screening method for the identification of a characteristic of a target nucleic acid in a whole blood sample, including positioning a composition comprising whole blood and at least one preservative agent within a centrifuge, centrifugating the composition to isolate a plasma that includes at least one target nucleic acid for further analysis and analyzing the at least one target nucleic acid to identify a characteristic about the at least one target nucleic acid, and a composition including the plasma, the preservative agent, and any other ingredient, which is produced by the method.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
C12Q 1/686 - Réaction en chaine par polymérase [PCR]
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Diagnostic preparations for storage, control and transportation of hematology samples in collection tubes for scientific or research use; chemicals and chemical preparations to facilitate the storage, control and transportation of blood and other biological samples.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Diagnostic preparations for storage, control and transportation of hematology samples in collection tubes for scientific or research use; chemicals and chemical preparations to facilitate the storage, control and transportation of blood and other biological samples.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Diagnostic preparations for storage, control and transportation of hematology samples in collection tubes for scientific or research use; chemicals and chemical preparations to facilitate the storage, control and transportation of blood and other biological samples.
43.
Compositions and methods for stabilizing circulating tumor cells
Compositions and Methods for Stabilizing Circulating Tumor Cells Methods and compositions for stabilizing a biological sample for analysis, comprising the steps of obtaining in a sample collection device a biological sample from a subject, especially blood, the biological sample including at least one circulating tumor cell from the subject. The methods may include a step of contacting the biological sample with a protective agent composition that includes a preservative agent, an optional anticoagulant, and a quenching agent to form a mixture that includes the protective agent composition and the sample.
An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate detection of stationary samples, reduced sample read time, and simultaneous reading of multiple light wavelengths.
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
C09K 15/20 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'azote et de l'oxygène
47.
Methods for preservation of cell-free nucleic acids
Methods for preserving and processing cell-free nucleic acids are disclosed. The method includes a blood collection tube including a composition formulated for stabilizing cell-free nucleic acids within a blood sample. The composition includes least one formaldehyde releaser preservative agent; ethylenediaminetetraacetic acid (EDTA); and one or more solvents; and at least some formaldehyde and up to about 1% formaldehyde as a result of the at least one formaldehyde releaser preservative agent. The collected blood sample is storable for at least, or about 7 days without cell lysis and without cell-free nucleic acid degradation of the blood sample due to DNase and RNase activity after blood draw. The method may include isolating the cell free nucleic acids from the stabilized blood sample and testing the isolated cell free nucleic acids from the stabilized blood sample to identify the presence, absence or severity of a disease state.
C12P 19/34 - Polynucléotides, p. ex. acides nucléiques, oligoribonucléotides
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
C09K 15/20 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'azote et de l'oxygène
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use. Diagnostic preparations for storage, control and transport
of hematology samples for medical purposes. Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use. Diagnostic preparations for storage, control and transport
of hematology samples for medical purposes. Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use;
hematology reference controls for in vitro scientific or
research diagnostic use; in vitro diagnostic reagents,
namely, hematology, chemical and immunology controls for
scientific or research use; diagnostic kits comprised of
reagents and assays for identifying gram-negative resistant
bacteria for research purposes; enzymes for medical research
purposes. Diagnostic preparations for storage, control and transport
of hematology samples; hematology reference controls for in
vitro medical diagnostic use. Laboratory equipment and supplies, namely, thermometers, PCR
systems comprised of computer hardware, computer software
for operating PCR instruments and tabulating test results,
and thermocycler apparatus, PCR kits comprising DNA
microarrays, DNA probes and equipment for conducting DNA
assays, automated erythrocyte sedimentation measuring
equipment, and erythrocyte sedimentation racks. Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use;
hematology reference control reagents for in vitro
scientific or research diagnostic use; in vitro diagnostic
reagents, namely, hematology, chemical and immunology
controls for scientific or research use; diagnostic kits
comprised of reagents and assays for identifying
gram-negative resistant bacteria for research purposes;
enzymes for medical research purposes. Diagnostic preparations for storage, control and transport
of hematology samples; hematology reference control reagents
for in vitro medical diagnostic use. Laboratory equipment and supplies, namely, thermometers, PCR
systems comprised of computer hardware, computer software
for operating PCR instruments and tabulating test results,
and thermocycler apparatus, PCR kits comprising DNA
microarrays, DNA probes and DNA assays, automated
erythrocyte sedimentation measuring equipment, and
erythrocyte sedimentation racks. Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use;
hematology reference controls for in vitro scientific or
research diagnostic use; in vitro diagnostic reagents,
namely, hematology, chemical and immunology controls for
scientific or research use; diagnostic kits comprised of
reagents and assays for identifying gram-negative resistant
bacteria for research purposes; enzymes for medical research
purposes. Diagnostic preparations for storage, control and transport
of hematology samples; hematology reference controls for in
vitro medical diagnostic use. Laboratory equipment and supplies, namely, thermometers, PCR
systems comprised of computer hardware, computer software
for operating PCR instruments and tabulating test results,
and thermocycler apparatus, PCR kits comprising DNA
microarrays, DNA probes and equipment for conducting DNA
Assays, automated erythrocyte sedimentation measuring
equipment, and erythrocyte sedimentation racks. Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use;
hematology reference control reagents for in vitro
scientific or research diagnostic use; in vitro diagnostic
reagents, namely, hematology, chemical and immunology
controls for scientific or research use; diagnostic kits
comprised of reagents and assays for identifying
gram-negative resistant bacteria for research purposes;
enzymes for medical research purposes. Diagnostic preparations for storage, control and transport
of hematology samples for medical use; hematology reference
controls in the nature of preparations for in vitro medical
diagnostic use. Laboratory equipment and supplies, namely, thermometers, pcr
systems comprised of computer hardware, computer software
for operating pcr instruments and tabulating test results,
and thermocycler apparatus, pcr kits comprising dna
microarrays, dna probes and dna assays, automated
erythrocyte sedimentation measuring equipment, and
erythrocyte sedimentation racks. Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use;
hematology reference controls for in vitro scientific or
research diagnostic use; in vitro diagnostic reagents,
namely, hematology, chemical and immunology controls for
scientific or research use; diagnostic kits comprised of
reagents and assays for identifying gram-negative resistant
bacteria for research purposes; enzymes for medical research
purposes. Diagnostic preparations for storage, control and transport
of hematology samples; hematology reference controls for in
vitro medical diagnostic use. Laboratory equipment and supplies, namely, thermometers, PCR
systems comprised of computer hardware, computer software
for operating PCR instruments and tabulating test results,
and thermocycler apparatus, PCR kits comprising DNA
microarrays, DNA probes and equipment for conducting DNA
assays, automated erythrocyte sedimentation measuring
equipment, and erythrocyte sedimentation racks Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use;
hematology reference controls for in vitro scientific or
research diagnostic use; in vitro diagnostic reagents,
namely, hematology, chemical and immunology controls for
scientific or research use; diagnostic kits comprised of
reagents and assays for identifying gram-negative resistant
bacteria for research purposes; enzymes for medical research
purposes. Diagnostic preparations for storage, control and transport
of hematology samples; hematology reference controls for in
vitro medical diagnostic use. Laboratory equipment and supplies, namely, thermometers, PCR
systems comprised of computer hardware, computer software
for operating PCR instruments and tabulating test results,
and thermocycler apparatus, PCR kits comprising DNA
microarrays, DNA probes and equipment for conducting DNA
assays, automated erythrocyte sedimentation measuring
equipment, and erythrocyte sedimentation racks. Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Diagnostic preparations for storage, control and transport of hematology samples for scientific or research use; hematology reference controls for in vitro scientific or research diagnostic use; in vitro diagnostic reagents, namely, hematology, chemical and immunology controls for scientific or research use; diagnostic kits comprised of reagents and assays for identifying gram-negative resistant bacteria for research purposes; enzymes for medical research purposes
(2) Diagnostic preparations for medical purposes for storage, control and transport of hematology samples; hematology reference controls for in vitro medical diagnostic use
(3) Laboratory equipment and supplies, namely, thermometers, polymerase chain reaction (PCR) systems comprised of computer hardware, computer software for operating quantitative PCR instruments and tabulating test results, and thermal cyclers, PCR kits comprising DNA microarrays, DNA probes and DNA assays, automated erythrocyte sedimentation measuring equipment, and erythrocyte sedimentation racks
(4) Blood testing apparatus, namely, blood collecting tubes
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Diagnostic preparations for storage, control and transport of hematology samples for scientific or research use; hematology reference controls for in vitro scientific or research diagnostic use; in vitro diagnostic reagents, namely, hematology, chemical and immunology controls for scientific or research use; diagnostic kits comprised of reagents and assays for identifying gram-negative resistant bacteria for research purposes; enzymes for medical research purposes.
(2) Diagnostic preparations for medical purposes for storage, control and transport of hematology samples; hematology reference controls for in vitro medical diagnostic use.
(3) Laboratory equipment and supplies, namely, thermometers, polymerase chain reaction (PCR) systems comprised of computer hardware, computer software for operating quantitative PCR instruments and tabulating test results, and thermal cyclers, PCR kits comprising DNA microarrays, DNA probes and DNA assays, automated erythrocyte sedimentation measuring equipment, and erythrocyte sedimentation racks.
(4) Blood testing apparatus, namely, blood collecting tubes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Diagnostic preparations for storage, control and transport of hematology samples for scientific or research use; hematology reference controls for in vitro scientific or research diagnostic use; in vitro diagnostic reagents, namely, hematology, chemical and immunology controls for scientific or research use; diagnostic kits comprised of reagents and assays for identifying gram-negative resistant bacteria for research purposes; enzymes for medical research purposes
(2) Diagnostic preparations for medical purposes for storage, control and transport of hematology samples; hematology reference controls for in vitro medical diagnostic use
(3) Laboratory equipment and supplies, namely, thermometers, polymerase chain reaction (PCR) systems comprised of computer hardware, computer software for operating quantitative PCR instruments and tabulating test results, and thermal cyclers, PCR kits comprising DNA microarrays, DNA probes and DNA assays, automated erythrocyte sedimentation measuring equipment, and erythrocyte sedimentation racks
(4) Blood testing apparatus, namely, blood collecting tubes
59.
Devices and compositions for preservation of cell-free nucleic acids
Devices including a composition for preserving and processing cell-free nucleic acids located within a blood sample and methods of using the same are disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The device may include a direct blood draw tube comprising a composition formulated for stabilizing cell-free nucleic acids within a blood sample including one or more formaldehyde releaser preservative agents, ethylenediaminetetraacetic acid (EDTA), one or more solvents, and formaldehyde. The composition is free of separately added formaldehyde but contains the formaldehyde as a result of the one or more formaldehyde releaser preservative agents. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic Preparations for Storage, Control and Transport of Hematology Samples for Scientific or Research Use; Hematology reference controls for in Vitro scientific or research Diagnostic Use; In vitro diagnostic reagents, namely, hematology, chemical and immunology controls for scientific or research use; Diagnostic kits comprised of reagents and assays for identifying gram-negative resistant bacteria for research purposes; Enzymes for Medical Research Purposes Diagnostic Preparations for Storage, Control and Transport of Hematology Samples for medical use; Hematology reference controls in the nature of preparations for in Vitro medical Diagnostic Use Laboratory equipment and supplies, namely, thermometers, PCR systems comprised of computer hardware, computer software for operating PCR instruments and tabulating test results, and thermocycler apparatus, PCR kits comprising DNA microarrays, DNA probes and DNA assays, automated erythrocyte sedimentation measuring equipment, and Erythrocyte sedimentation racks Blood testing apparatus, namely, blood collecting tubes
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic Preparations for Storage, Control and Transport of Hematology Samples for Scientific or Research Use; Hematology reference controls for in Vitro scientific or research Diagnostic Use; In vitro diagnostic reagents, namely, hematology, chemical and immunology controls for scientific or research use; Diagnostic kits comprised of reagents and assays for identifying gram-negative resistant bacteria for research purposes; Enzymes for Medical Research Purposes Diagnostic Preparations for Storage, Control and Transport of Hematology Samples for medical use; Hematology reference controls in the nature of preparations for in Vitro medical Diagnostic Use Laboratory equipment and supplies, namely, thermometers, PCR systems comprised of computer hardware, computer software for operating PCR instruments and tabulating test results, and thermocycler apparatus, PCR kits comprising DNA microarrays, DNA probes and DNA assays, automated erythrocyte sedimentation measuring equipment, and Erythrocyte sedimentation racks Blood testing apparatus, namely, blood collecting tubes
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic Preparations For Storage, Control And Transport Of Hematology Samples For Scientific Or Research Use; Hematology Reference Controls For In Vitro Scientific Or Research Diagnostic Use; In Vitro Diagnostic Reagents, Namely, Hematology, Chemical And Immunology Controls For Scientific Or Research Use; Diagnostic Kits Comprised Of Reagents And Assays For Identifying Gram-Negative Resistant Bacteria For Research Purposes; Enzymes For Medical Research Purposes Diagnostic Preparations for Storage, Control and Transport of Hematology Samples for medical use; Hematology reference controls in the nature of preparations for in Vitro medical Diagnostic Use Laboratory Equipment And Supplies, Namely, Thermometers, PCR Systems Comprised Of Computer Hardware, Computer Software For Operating PCR Instruments And Tabulating Test Results, And Thermocycler Apparatus, PCR Kits Comprising DNA Microarrays, DNA Probes And DNA Assays, Automated Erythrocyte Sedimentation Measuring Equipment, And Erythrocyte Sedimentation Racks Blood testing apparatus, namely, blood collecting tubes
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use. Diagnostic preparations for storage, control and transport
of hematology samples. Blood testing apparatus, namely, blood collecting tubes.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Procedural controls in the nature of chemical reagents for medical and veterinary purposes, namely, stable white blood cell reference control for use in immunophenotyping by flow cytometry
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Procedural controls in the nature of chemical reagents for medical and veterinary purposes, namely, stable white blood cell reference control for use in immunophenotyping by flow cytometry
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic preparations for storage, control and transport
of hematology samples for scientific or research use. Diagnostic preparations for storage, control and transport
of hematology samples. Blood testing apparatus, namely, blood collecting tubes.
A method relating to preparation of a biological sample for analysis by flow cytometry including contacting a drawn blood sample with a protective agent that is substantially free of formaldehyde and analyzing the white blood cells of the contacted sample for protein epitopes after at least about twenty-four hours after contacting.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Reagents for in vitro diagnostic use, namely, an assayed
control containing actual sperm for monitoring sperm counts
performed manually using a hemocytometer to validate
quantification of sperm in a controlled laboratory
environment.
A composition and method for preserving a urine sample and a preservative delivery vessel are disclosed wherein treatment of the urine sample aids in preserving circulating cell-free nucleic acids in urine over a wide range of dilution ratios within temperature fluctuations that can occur during urine sample handling, storage and transportation. The urine sample preservation composition and method and preservative delivery vessel provide a method for obtaining high quality stabilized urinary cell-free nucleic acids for clinical diagnostics development and application.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate detection of stationary samples, reduced sample read time, and simultaneous reading of multiple light wavelengths.
Methods and compositions for stabilizing a biological sample for analysis, comprising the steps of obtaining in a sample collection device a biological sample from a subject, the biological sample including at least one circulating tumor cell from the subject. The methods may include a step of contacting the biological sample with a protective agent composition that includes a preservative agent, an optional anticoagulant, and a quenching agent to form a mixture that includes the protective agent composition and the sample.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
Produits et services
Clinical medical and veterinary diagnostic reagents and preparations for use in polymerase chain reaction analysis. Laboratory instruments and tubes for the purpose of performing polymerase chain reaction tests for medical and veterinary use.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Reagents For In Vitro Diagnostic Use, Namely, An Assayed Control Containing Actual Sperm For Monitoring Sperm Counts Performed Manually Using A Hemocytometer To Validate Quantification Of Sperm In A Controlled Laboratory Environment
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C09K 15/20 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'azote et de l'oxygène
80.
Real-time optical system for polymerase chain reaction
An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate reduced sample read time and rapid reading of multiple light wavelengths.
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c.-à-d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
The present invention is directed at a composition comprising a live swine flu virus having an infectious component and a plurality of surface antigens in contact with a formaldehyde donor agent having a molecular weight that is less than about 400 g/mol. Preferably, the formaldehyde donor agent is selected from a non-crosslinking chemical fixative that contains urea.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Procedural controls in the nature of chemical reagents for medical and veterinary purposes, namely, stable white blood cell reference control for use in immunophenotyping by flow cytometry
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Procedural controls in the nature of chemical reagents for medical or veterinary purposes, namely, stable white blood cell reference control for use in immunophenotyping by flow cytometry
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Procedural controls in the nature of chemical reagents for medical and veterinary purposes, namely, stable white blood cell reference control for use in immunophenotyping by flow cytometry
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Procedural controls in the nature of chemical reagents for medical and veterinary purposes, namely, stable white blood cell reference control for use in immunophenotyping by flow cytometry
A thermocycling device and method of operating a thermocycler instrument, the instrument including a sample holder, at least one thermal cycling element, and at least one first and second temperature sensors, for causing the sample holder containing the at least one sample to undergo polymerase chain reaction amplification by repeated cycling between at least a denaturation heating stage and an annealing cooling stage. The first temperature corresponding with the temperature of the sample holder is monitored using the at least one first temperature sensor, and a second temperature corresponding with the temperature external of the sample holder is monitored using the at least one second temperature sensor. Based upon the first temperature and the second temperature, the power that is delivered to the at least one thermal cycling element of the instrument is dynamically controlled.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
B01L 7/00 - Appareils de chauffage ou de refroidissementDispositifs d'isolation thermique
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
An improved tube including a closure portion, a strap integrally connected to the closure portion and being configured for defining a living hinge, a body portion having a longitudinal axis and an outer wall generally circumscribing the longitudinal axis, and being integrally and hingedly connected with the closure portion by way of the strap. The body portion including a sample portion being generally elongated along the longitudinal axis and being configured for elastic deformation along a portion of its length, including in a direction that is generally transverse to the longitudinal axis so that at least a portion of the wall structure compressively and resiliently deforms and engages a wall defining an opening in a sample block of a polymerase chain reaction amplification device, and the first outer wall dimension of the sample portion reduces to a smaller second outer wall dimension.
By way of summary, the present invention meets some or all of the above needs by providing in a first aspect a method comprising contacting red blood cells in a suspension medium containing mannose under conditions such that the concentration of S-Alc glycated hemoglobin is increased to greater than about 6 percent by weight of the hemoglobin in the red blood cells. Preferably the suspension medium is an aqueous suspension medium. In preferred embodiments, the method is performed at about ambient temperature, 18° C. to about 23° C.
G01N 31/00 - Recherche ou analyse des matériaux non biologiques par l'emploi des procédés chimiques spécifiés dans les sous-groupesAppareils spécialement adaptés à de tels procédés
95.
Cis di-ahl modified controls for glycated hemoglobin S-A1c derived from healthy blood cells
The invention is composition comprising red blood cells in an aqueous suspension medium and one or more cis di-ahls; wherein more than 6 percent by weight of the hemoglobin in the red blood cells is S-Alc glycated hemoglobin. In another embodiment, the invention is a method comprising contacting red blood cells in a suspension medium having a concentration of S-Alc glycated hemoglobin of greater than 6 percent by weight of the hemoglobin in the red blood cells with a sufficient amount of one or more cis di-ahls such that the concentration of S-Alc glycated hemoglobin in resulting composition as measured by high pressure liquid chromatography, immunoassay and boronate affinity methods is consistent.
G01N 31/00 - Recherche ou analyse des matériaux non biologiques par l'emploi des procédés chimiques spécifiés dans les sous-groupesAppareils spécialement adaptés à de tels procédés
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Diagnostic reagents for use as a procedural control for use in monitoring total cell counts and white cell differentiation in body fluids, namely, spinal fluid, synovial fluid, peritoneal fluid, pericardial fluid, and pleural fluid
97.
Thermocycler and sample vessel for rapid amplification of DNA
A thermocycler apparatus and method for rapidly performing the PCR process employs at least two thermoelectric modules which are in substantial spatial opposition with an interior space present between opposing modules. One or multiple sample vessels are placed in between the modules such that the vessels are subjected to temperature cycling by the modules. The sample vessels have a minimal internal dimension that is substantially perpendicular to the modules that facilitates rapid temperature cycling. In embodiments of the invention the sample vessels may be deformable between: a) a shape having a wide mouth to facilitate filling and removing of sample fluids from the vessel, and b) a shape which is thinner for conforming to the sample cavity or interior space between the thermoelectric modules of the thermocycler for more rapid heat transfer.
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
