09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Instruments and apparatus for performing chromatography, for the measurement of weight, size, shape, density, structure, concentration and characteristics of particles, molecules and macromolecules; instruments and apparatus performing optical image analysis, for the measurement weight, size, shape, density, structure, concentration and characteristics of particles, molecules and macromolecules; instruments and apparatus using laser diffraction and scattering, for the measurement of weight, size, shape, density, structure, concentration and characteristics of particles, molecules and macromolecules; scientific, industrial and laboratory apparatus and instruments for counting, sizing, classifying, differentiating and identifying particles in solids, liquids or gases; instruments for measuring rheological properties, namely, viscometers, rotary and capillary rheometers; instruments for measuring dimensional information of particles, namely, particle size, shape, density, structure and composition analysers; particle size and shape distribution and concentration measuring instruments, namely, particle counting instruments, air and liquid particle counters, photocorrelation spectroscopy instruments, instruments for producing zimm plots to determine the molecular weight of polymers, acoustic spectroscopy instruments, and laser diffraction measuring instruments; particle charge measuring instruments, namely, zeta potential measuring instruments, electrophoretic mobility measuring instruments, particle mobility measuring instruments, Ph measuring instruments, and micro electrophoresis measuring instruments; instruments for measuring the amount of heat involved in a chemical reaction or other process, namely, calorimeters; instruments for measuring molecular diffusion coefficient and hydrodynamic of molecules, namely, instruments that produce Taylor Dispersion Analysis plots; scientific and measuring apparatus and instruments, namely, spectrometers, X-ray fluorescence analyzers and spectrometers, diffractometers, X-ray diffractometers and wafer analyzers, neutron activation analyzers, pulsed fast and thermal neutron activation analyzers; analytical apparatus for use in analyzing samples of composites for use in scientific, industrial and laboratory applications, namely, X-ray diffraction and spectrometry apparatus, diffractometers, X-ray diffractometers, X-ray analysers, X-ray fluorescence spectrometers, wafer analysers, X-ray tubes; materials characterization apparatus, namely, scientific and measuring apparatus and instruments, namely, spectrometers, X-ray fluorescence analyzers and spectrometers, diffractometers, X-ray diffractometers and wafer analyzers; X-ray apparatus not for medical use; analytical, process control and measuring apparatus, namely, reflectometers, spectrometers, X-ray fluorescence analyzers and X-ray diffraction meters; analytical, process control and measuring apparatus, namely, reflectometers, spectrometers, X-ray fluorescence analyzers and X-ray diffraction meters for the cement, steel, aluminium, petrochemicals, industrial minerals, glass and polymers industry, and to customers in research and development institutions; metrology tools, namely, reflectometers, spectrometers, X-ray fluorescence analyzers and X-ray diffraction meters; reflectometers, spectrometers, X-ray fluorescence analyzers and X-ray diffraction meters for both silicon and compound semiconductor applications; X-ray fluorescence wafer and disc analyzers; X-ray fluorescence wafer and disc analyzers for the silicon semiconductor industry, for analyzing film thickness, composition and density; X-ray diffraction instruments, namely, X-ray diffraction meters for the compound semiconductor industry; X-ray tubes, not for medical purposes; X-ray detectors; laboratory equipment, namely, crucibles, flasks, stirrers, Petri dishes, electrodes; laboratory apparatus, namely, scales, mechanical dispensers, robots, namely, robots for weighing and dosing samples and dispensing the flux for use in analysis by X-ray Fluorescence analysis (XRF), Atomic Absorption analysis (AA), Inductively Coupled Plasma analysis (ICP) and wet chemistry analysis for the ceramic, cement, steel, aluminium, glass, polymer, mining, lime, bauxite, ferroalloy, pure metal, catalyst, geology and mineral prospecting, petroleum and oil industries; gas and electric automatic fusion apparatuses, namely, laboratory robots, namely, robots for use in X-ray Fluorescence analysis (XRF), Atomic Absorption analysis (AA), Inductively Coupled Plasma analysis (ICP) and wet chemistry analysis for the ceramic, cement, steel, aluminium, glass, polymer, mining, lime, bauxite, ferroalloy, pure metal, catalyst, geology and mineral prospecting, petroleum and oil industries; electric fusion instruments, namely, automatic fluxer for sample fusing in the cement, lime, carbonate, ceramic, glass, slag, refractory, mining and geological, silicate, clay, ores, sulphide, fluoride, bauxite, aluminium, catalyst, polymer, pigment, steel, pure metal, ferroalloy, non-ferrous alloy and pharmaceutical industries; laboratory weighing apparatus and instruments and balances; apparatus for separating and preparing samples, suspensions, sprays, and emulsions of particles for use with any of the aforesaid goods, namely, gel permeation chromatography, sample dispersion units, stirred cells, autosamplers, dry powder feeders, dispensers, auto titrators, nebulizers, ultrasonic baths, and temperature controllers; instrument controllers, namely, computers, digital signal processors and microprocessors, computer printers; machine readable data carriers, namely, solid state memory devices, optical or magnetic storage media disks, magnetic tapes, all sold pre-programmed with control or analysis programs for use with the all of the aforesaid goods; computer software and hardware for controlling and operating all of the aforesaid goods and for analysing measurements made by all of the aforesaid goods; computer software for use in relation to the standardless analysis of samples; parts and fittings for all the aforesaid goods Scientific and technological services, namely, scientific laboratory services, and research and design relating thereto; consultancy, advisory, and data analytics, and laboratory services related to scientific and industrial instruments and components thereof; scientific laboratory services; laboratory analysis, testing, and research all in the field of materials analysis, industrial process control and optimisation; science and technology services, namely, scientific research in the field of measurement of weight, chemical composition, size, shape, structure, concentration and characteristics of particles, molecules and macromolecules; scientific and technological analytics in the field of measurement of weight, chemical composition, size, shape, structure, concentration and characteristics of particles, molecules and macromolecules; industrial analysis and research services in the field of materials analysis, industrial process control and optimisation; leasing and rental services in the field of laboratory apparatus and equipment; the leasing and rental of scientific and measuring apparatus and instruments; the design of scientific and measuring apparatus and instruments; design, development and programming of computer hardware and software; testing of laboratory apparatus and equipment, authentication in the field of materials analysis, and quality control for others; information and consultancy services all relating to the aforesaid
09 - Appareils et instruments scientifiques et électriques
Produits et services
Scientific instruments and apparatus for particle analysis, namely, the measurement of weight, chemical composition, size, shape, structure, concentration and characteristics of particles, molecules and macromolecules and replacement parts therefor; scientific instruments and apparatus for particle analysis, namely, performing optical image analysis, for the measurement weight, size, shape, structure, concentration and characteristics of particles, molecules and macromolecules and replacement parts therefor; computer software for controlling and operating all of the aforesaid goods and for analyzing measurements made by all of the aforesaid goods
A cuvette carrier (100) comprising: a plurality of walls (101) defining a holding volume (102) for a cuvette (109); a first (103) and second (104) transmissive region included in the plurality of walls (101); and a first optical polariser (103) arranged to polarise light passing through the first transmissive region (103).
A method of determining a relationship between a mutual diffusion co-efficient Dm and the concentration c of a solute within a solvent. The method comprises: obtaining a Taylorgram ( 100) comprising a plurality of measurements of solute concentration c; and deriving from the Taylorgram (200) a plurality of mutual diffusion coefficient values Dm corresponding with a plurality of different concentrations c of solute in the solvent.
G01N 15/06 - Recherche de la concentration des suspensions de particules
G01N 35/08 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet en utilisant un courant d'échantillons discrets circulant dans une canalisation, p.ex. analyse à injection dans un écoulement
The invention relates to methods and apparatus for detecting properties of heterogeneous samples, including detecting properties of particles or fluid droplets in industrial processes. Embodiments disclosed include a particle characterization method, comprising: providing a fluid containing suspended particles; causing at least a first subset of the suspended particles to flow past a first two-dimensional array detector (24); illuminating the first subset of suspended particles as they flow past the first two-dimensional array detector (24) in the fluid; acquiring a plurality of images of the first subset of particles as they flow past the first two-dimensional array detector (24) in the fluid; and automatically counting the particles in the images.
G01N 1/00 - Echantillonnage; Préparation des éprouvettes pour la recherche
G01N 15/14 - Recherche par des moyens électro-optiques
B07C 5/342 - Tri en fonction d'autres propriétés particulières selon les propriétés optiques, p.ex. la couleur
G01N 15/10 - Recherche de particules individuelles
G01N 15/00 - Recherche de caractéristiques de particules; Recherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux
Disclosed is a method of calibrating apparatus for optically characterizing samples of particles of small size. Also disclosed is a method of estimating the concentration of particles in a population of small size particles.
G01N 15/06 - Recherche de la concentration des suspensions de particules
G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
G01N 1/28 - Préparation d'échantillons pour l'analyse
G01N 33/483 - Analyse physique de matériau biologique
G01N 15/00 - Recherche de caractéristiques de particules; Recherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux
B82Y 35/00 - Procédés ou appareils pour la mesure ou l’analyse des nanostructures
A method of estimating a parameter for fitting a multi-component Taylorgram model (603, 604, 605, 606) to Taylorgram data g(t) is disclosed. The data (601, 602) comprises a multi-component Taylorgram peak or front at t = tr. The method comprises: evaluating a value of an integration or differential of the data; determining the parameter, based on an analytical expression that includes the value of the integral or differential of the data, the parameter corresponding with a physical property of a sample from which the Taylorgram data was obtained.
G06F 17/18 - Opérations mathématiques complexes pour l'évaluation de données statistiques
G01N 13/00 - Recherche des effets de surface ou de couche limite, p.ex. pouvoir mouillant; Recherche des effets de diffusion; Analyse des matériaux en déterminant les effets superficiels, limites ou de diffusion
An apparatus (10) for characterizing particles, comprising: a microscope objective with an optical axis and a depth of field; a holder cell (22) configured to position the particles in a generally planar volume below the microscope objective, the planar volume being substantially normal to the optical axis and having a depth that is less than or equal to the depth of field, wherein a portion of the cell holder (22) for positioning in the optical axis of the microscope objective is substantially free of significant spectral features in a Raman spectral range; an x-y stage (20) to move the microscope objective relative to the holder cell (22) in x and y directions to align particles with the optical axis of the microscope objective while the particles are held by the holder cell (22), a detector ( 18) for acquiring an image of a particle through the microscope objective, a laser operable to illuminate a particle held by the holder cell (22), a Raman spectrometer ( 16) arranged to obtain a spectrum including the Raman spectral range from the illuminated particle, and characterizing logic operative to characterize the particle based on image processing operations performed on the acquired image and based on the Raman spectrum. The holder cell (22) comprises a first plate (34) and a second plate (36) that are separated by a predetermined distance defining the planar volume depth.
A particle characterisation apparatus (300) is disclosed comprising: a sample cell (110) for holding a sample (150), a light source (302) for producing a light beam (106) for illuminating the sample (150) in the sample cell (110), thereby producing scattered light by the interaction of the light beam (106) with the sample (150); a focussing lens (130) for focussing the light beam (106) within the sample (150); and a detector (306) for detecting the backscattered light along a detection optical path (108) that intersects the focussed light beam (106) within the sample (150). The intersection of the light beam (106) and the detection optical path (108) in the sample define a detection region (120). The apparatus comprises an optical arrangement for varying the volume of the detection region (120).
G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
G01N 21/51 - Dispersion, c. à d. réflexion diffuse dans un corps ou dans un fluide à l'intérieur d'un récipient, p.ex. dans une ampoule
G01N 15/00 - Recherche de caractéristiques de particules; Recherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux
G01N 21/47 - Dispersion, c. à d. réflexion diffuse
A particle characterization apparatus and corresponding method is disclosed. The apparatus comprises a sample cell (14). The sample cell includes: an input opening (26) for receiving a fluid that carries particles flowing along a flow axis, a central acquisition channel (32) hydraulically responsive to the input opening (26) for receiving a first subset of the fluid,a pair of lateral bypass channels (32, 34) hydraulically responsive to the input opening (26) and disposed on either side of the central acquisition channel (32) for receiving second and third subsets of the fluid,a window (36) in the central acquisition channel (32) for illuminating the first subset of the fluid in the central acquisition channel (32),an illumination source (18) positioned to illuminate the fluid in the central acquisition channel (32) through the window (36), and a detector (20) positioned to receive light from the fluid in the central acquisition channel (32) after it has interacted with the fluid.
A method of Raman spectroscopic structure investigation of a sample that includes a dispersed chemical species, in particular a protein, in a liquid phase and an apparatus for performing said method are described. The method comprises: providing the sample; providing marker particles in the sample; exciting the sample with a light source; receiving Raman-scattered light from the dispersed chemical species in the sample; detecting, from the received Raman-scattered light, Raman scattering from the dispersed chemical species in the sample; detecting movement of the marker particles in the sample; and extracting at least one characteristic of the dispersed chemical species in the sample from both the step of detecting Raman scattering and the step of detecting movement of the particles.
G01N 11/00 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement
The invention relates to methods and apparatus for detecting properties of heterogeneous samples, including detecting properties of particles or fluid droplets in industrial processes. Embodiments disclosed include a particle characterization method, comprising: providing a fluid containing suspended particles; causing at least a first subset of the suspended particles to flow past a first two-dimensional array detector (24); illuminating the first subset of suspended particles as they flow past the first two-dimensional array detector (24) in the fluid; acquiring a plurality of images of the first subset of particles as they flow past the first two-dimensional array detector (24) in the fluid; and automatically counting the particles in the images.
The invention relates to methods and apparatus for measurement of viscosity of liquids using a rotational rheometer. Embodiments disclosed include a method of measuring viscosity of a liquid sample using a rotational rheometer ( 100) comprising first and second parts (101,102) having opposing respective first and second measurement surfaces (103, 104), a motor (105) connected to the second part (102) for rotating the second part ( 102) relative to the first part (101) and a rotational position sensor (106) for measurement of rotation of the second part (102) relative to the first part (101), the method comprising the sequential steps of: disposing the liquid sample (107) between the first and second measurement surfaces (103,104); applying a driving signal corresponding to a requested torque to the motor (105) to rotate the second part (102) relative to the first part (101) in a first direction; recording rotation of the second part (102) with the rotational position sensor ( 106) and a derived measure of torque while the second part (102) rotates in the first direction; reversing the driving signal to rotate the second part (102) relative to the first part (101) in a second opposing direction; recording rotation of the second part (102) with the rotational position sensor (106) and a derived measure of torque while the second part (102) rotates in the second direction; and calculating a measure of viscosity of the liquid sample (107) using a combination of the rotational position over time and the derived measure of torque in the first and second directions.
G01N 11/14 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en déplaçant un corps à l'intérieur du matériau en utilisant des corps en rotation, p.ex. moulinet
G01N 11/16 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en déplaçant un corps à l'intérieur du matériau en mesurant l'effet d'amortissement sur un corps oscillant
14.
IMPROVEMENTS IN OR RELATING TO CALIBRATION OF INSTRUMENTS
Disclosed is a method of calibrating apparatus for optically characterising samples of particles of small size comprising the steps of: (a)introducing into the apparatus a sample of a calibration population of particles which is (i) substantially monodisperse and (ii) homogeneous and (iii) has a known concentration of particles in terms of number per unit volume; (b)analysing the sample, under appropriate conditions to determine, for a particular combination of apparatus conditions or settings, the number of particles detected and the average brightness of individually detected and measured particles; (c)adjusting the apparatus to a new particular combination of apparatus conditions or settings and analysing the same sample, or another sample of the same calibration population as in step (a), and repeating the analysis of step (b) to determine the number of particles detected and the average brightness of detected particles under the new combination of apparatus conditions or settings; (d)optionally repeating step (c) at one or more further new particular combinations of apparatus conditions or settings; and (e)deriving from the analyses a calibration plot or look-up table of brightness of particle against number of particles detected, which is used to calibrate the apparatus against subsequent analysis of populations of particles of unknown concentration, to determine an estimate of the concentration thereof.
The invention relates to methods and apparatus for detecting properties of suspended particles. Embodiments disclosed include an optical instrument (200) for detecting properties of a sample, comprising: a sample cell (103) for holding a sample of a particulate dispersion; a coherent light source (101) configured to illuminate the sample in the sample cell (103); a light intensity detector (104, 106) positioned to receive and measure an intensity of light from the coherent light source (101) elastically scattered by the sample in the sample cell (103); and a spectral light detector (212) positioned and configured to receive and measure a range of wavelengths of light from the coherent radiation source (101) inelastically scattered by the sample in the sample cell (103).
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c. à d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
G01N 21/51 - Dispersion, c. à d. réflexion diffuse dans un corps ou dans un fluide à l'intérieur d'un récipient, p.ex. dans une ampoule
G01J 3/44 - Spectrométrie Raman; Spectrométrie par diffusion
G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
Apparatus (100) for measuring particle size distribution by light scattering comprises a blue LED (102) and a 633 nm helium neon laser (104). Light output from the LED and laser is separately passed or reflected by a dichroic element (116) onto a common path through a sample cell (122) containing a sample, the particle size distribution of which is to be measured. Light scattered from the sample cell is detected by one or more detectors (112B-H). Light transmitted by the sample cell is detected by detectors 112A, 112J. Output signals from one or more of the detectors are passed to a computation unit (114) which calculates particle size distribution. A small percentage of light from the blue LED is reflected by the dichroic element to a detector (110). Similarly, a small percentage of light from the laser is passed by the dichroic element to the detector. Output signals from the detector are fed back to control units (106, 108) to stabilize the output power of the LED and laser.
A particle characterisation apparatus is disclosed comprising: a light source; a sample cell; a collecting lens and a detector. The light source is operable to illuminate a sample comprising dispersed particles within the sample cell with a light beam along a light beam axis. The light beam axis passes through a first wall of the sample cell, through the sample, and through a second wall of the sample cell, so as to produce scattered light by interactions with the sample. The detector is configured to detect light scattered from the sample. The second wall of the sample cell comprises a lens with a convex external surface through which the light beam axis passes. The collecting lens is arranged to collect and focus scattered light leaving the sample cell onto the detector,and comprises an aspheric surface.
An optical sample characterization method is disclosed comprising: holding a sample in a sample container ( 12; 32; 52; 1 52; 162) proximate at least one two-dimensional detector array assembly ( 14; 34; 44; 54; 144; 164), wherein the sample container has a first end and a second end; setting up a gradient between the first end of the sample container and the second end of the sample container; illuminating the sample between the first end of the sample container and the second end of the sample container; and detecting light received from the illuminated sample from the first end of the sample container to the second end of the sample container by the two-dimensional array assembly ( 14; 34; 44; 54; 144; 1 64).
The invention relates to analysing and controlling collection of liquid eluate output from a separation process, in particular by use of a measure of suspended material in the eluate based on a light scattering detection method. Exemplary embodiments include a method (300) of controlling collection of a sample of a liquid eluate output from a separation process, the method comprising: exposing (306) the liquid eluate to light from a light source; detecting (307) light from the light source scattered by suspended material in the eluate at a detector; and beginning and ending collection (310) of the sample when a measure of the suspended material derived from the detected scattered light enters and leaves a predetermined range.
A viscometer, comprising: a source of fluid pressure, a tube, an array of optical detectors, an acquisition driver circuit and viscosity computation logic. The tube has an inside volume that is hydraulically responsive to the source of fluid pressure. The array of optical detectors is positioned along a length of the first tube with a plurality of its detectors optically responsive to the inside volume of the first tube and including an image data output. The acquisition driver circuit is responsive to the image data output of the first array to acquire a series of successive images of the inside volume of the first tube. The viscosity computation logic is responsive to the acquisition driver circuit and operative to compute the viscosity of a fluid flowing along the first tube from the series of images of the inside volume of the first tube.
G01N 11/06 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en mesurant l'écoulement du matériau à travers un passage étroit, p.ex. un tube, une ouverture en chronométrant l'écoulement d'une quantité connue vers l'extérieur
G01N 11/04 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en mesurant l'écoulement du matériau à travers un passage étroit, p.ex. un tube, une ouverture
A single photon counting apparatus comprising a SPAD and a controller. The controller is operable to vary the operating parameters of the SPAD during use in response to a count rate detected by the SPAD. The operating parameters comprising at least one of the voltage across the SPAD during an active period, the voltage across the SPAD during a quench period, the duration of the quench period and the temperature of the SPAD. Particle characterisation instruments comprising the apparatus are also disclosed.
H01L 31/024 - Dispositions pour le refroidissement, le chauffage, la ventilation ou la compensation de température
H01L 31/107 - Dispositifs sensibles au rayonnement infrarouge, visible ou ultraviolet caractérisés par une seule barrière de potentiel ou de surface la barrière de potentiel fonctionnant en régime d'avalanche, p.ex. photodiode à avalanche
H04B 10/69 - Dispositions électriques dans le récepteur
22.
Method and apparatus for analyzing a sample of sub-micron particles
The present invention provides a method of analyzing a sample comprising sub-micron particles, comprising determining first information about the size of particles and number of particles in the sample by nanoparticle tracking analysis; determining second information about average particle size of particles in the sample by dynamic light scattering; determining from the first information third information representing the theoretical effect of the detected particles on results obtainable by dynamic light scattering; and adjusting the second information using the third information to produce fourth information representing adjusted information on average particle size.
G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
G01N 15/14 - Recherche par des moyens électro-optiques
G01N 15/00 - Recherche de caractéristiques de particules; Recherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux
The disclosure relates to methods and apparatus for detecting properties of heterogeneous samples, including detecting properties of particles or fluid droplets in industrial processes. Embodiments disclosed include a particle characterization method, comprising: suspending particles in a fluid; causing the suspended particles to flow past a two-dimensional array detector; illuminating the suspended particles as they flow past the two-dimensional array detector in the fluid; acquiring a plurality of images of the particles as they flow past the two-dimensional array detector in the fluid; and applying a particle characterization function to results of steps of acquiring a plurality of images for at least some of the suspended particles.
The disclosure relates to methods and apparatus for detecting properties of heterogeneous samples, including detecting properties of particles or fluid droplets in industrial processes. Embodiments disclosed include a heterogeneous fluid sample characterization method, comprising: inserting a probe into a first of a plurality of heterogeneous fluid samples; drawing at least a first portion of the first sample into the probe and past a two-dimensional array detector; illuminating the first portion of the first sample as it is drawn past the two-dimensional array detector; acquiring at least a first image of the first portion of the first sample as it is drawn past the two- dimensional array detector; inserting the probe into a second of the plurality of heterogeneous samples; drawing at least a first portion of the second sample into the probe and past a two-dimensional array detector; illuminating the first portion of the second sample as it is drawn past the two-dimensional array detector in the fluid; and acquiring at least a first image of the first portion of the second sample as it is drawn past the two-dimensional array detector in the fluid.
Apparatus (200) for measuring the particle-size distribution of a sample by light- scattering comprises a focusing optic (202) for producing a converging beam (203) generally along a propagation axis z. The apparatus comprises a mounting system which allows a dry sample cell (208A) and a wet sample cell (208B) to be mounted in the converging beam at different times and in respective planes which are mutually inclined so that in use of the apparatus respective positions (212, 214) at which transmitted light is focused for the two cells have a difference in displacement from the z axis that is less than for the case where the respective planes are substantially parallel. This allows use of a cheaper and less complex translation stage within the apparatus for mounting an optical detector for locating the two focus positions.
Apparatus (100) for measuring particle size distribution by light scattering comprises a blue LED (102) and a 633 nm helium neon laser (104). Light output from the LED and laser is separately passed or reflected by a dichroic element (116) onto a common path through a sample cell (122) containing a sample, the particle size distribution of which is to be measured. Light scattered from the sample cell is detected by one or more detectors (112B-H). Light transmitted by the sample cell is detected by detectors 112A, 112J. Output signals from one or more of the detectors are passed to a computation unit (114) which calculates particle size distribution. A small percentage of light from the blue LED is reflected by the dichroic element to a detector (110). Similarly, a small percentage of light from the laser is passed by the dichroic element to the detector. Output signals from the detector are fed back to control units (106, 108) to stabilise the output power of the LED and laser.
Apparatus for determining particle-size distribution of a sample by light-scattering includes a helium neon laser (102), a sample cell having cell windows (120, 122) and a focal plane detector (124). Detectors are also provided for detecting light scattered by a sample within or flowing through the sample cell. The apparatus includes a first (114) and second (116) folding mirrors arranged to fold the optical path from the laser to the sample cell so that the laser is vertically below the sample cell. The folding mirrors are mounted within a dust-proof housing (104), the entrance (106) and exit (108) components thereof being other optical components generally used within light- scattering apparatus. The entrance component is mounted such that its outward normal points downwards and the exit component is mounted substantially vertically so that these components do not accumulate dust. The invention allows the laser of a light-scattering apparatus to be positioned vertically below a sample cell of the apparatus without the accumulation of dust on optical components, which tends to degrade performance.
The invention relates to methods and apparatus for detecting properties of suspended particles. Embodiments disclosed include an optical instrument (200) for detecting properties of a sample, comprising: a sample cell (103) for holding a sample of a particulate dispersion; a coherent light source (101) configured to illuminate the sample in the sample cell (103); a light intensity detector (104, 106) positioned to receive and measure an intensity of light from the coherent light source (101) elastically scattered by the sample in the sample cell (103); and a spectral light detector (212) positioned and configured to receive and measure a range of wavelengths of light from the coherent radiation source (101) inelastically scattered by the sample in the sample cell (103).
The present invention provides a method of analysing a sample comprising sub-micron particles, comprising determining first information about the size of particles and number of particles in the sample by nanoparticle tracking analysis;determining second information about average particle size of particles in the sample by dynamic light scattering;determining from the first information third information representing the theoretical effect of the detected particles on results obtainable by dynamic light scattering; and adjusting the second information using the third information to produce fourth information representing adjusted information on average particle size.
In one general aspect, a spectroscopic apparatus is disclosed for investigating heterogeneity of a sample area. The apparatus includes an image acquisition system operative to acquire images of a plurality of sub-areas in the sample area and a sub-area selection interface operative to receive a selection designating one of the sub-areas for which an image has been obtained. A spectrometer has a field of view and is operative to acquire a spectrum of at least part of one of the sub-areas in its field of view, and a positioning mechanism is responsive to the sub-area selection interface and operative to position the field of view of the spectrometer relative to the sample area based on a received selection.
The invention relates to methods and apparatus for determining properties of a surface. Embodiments disclosed include an apparatus for measuring a surface charge of a sample, comprising: a sample holder having an opposed pair of electrodes and configured to hold a sample in position in a measurement volume between the electrodes such that a planar surface of the sample is aligned orthogonal to the electrode surfaces; a measurement chamber for containing a measurement liquid and having an open end configured to receive the sample holder to position the electrodes in a preset orientation; a laser light source positioned and configured to direct a laser beam through the measurement chamber between the electrodes and parallel to the planar surface of the sample when the sample holder is received in the measurement chamber; and a detector positioned and configured to detect scattered light from the measurement volume, wherein the apparatus is configured to allow for detection of the scattered light by the detector over a range of distances from the surface of the sample.
In one general aspect, an electrophoretic measurement method is disclosed that includes providing a vessel that holds a dispersant, providing a first electrode immersed in the dispersant, and providing a second electrode immersed in the dispersant. A sample is placed at a location within the dispersant between the first and second electrodes with the sample being separated from the electrodes, an alternating electric field is applied across the electrodes, and the sample is illuminated with temporally coherent light. A frequency shift is detected in light from the step of illuminating that has interacted with the sample during the step of applying an alternating electric field, and a property of the sample is derived based on results of the step of detecting.
G01P 5/00 - Mesure de la vitesse des fluides, p.ex. d'un courant atmosphérique; Mesure de la vitesse de corps, p.ex. navires, aéronefs, par rapport à des fluides
An in-line powder dispersion apparatus (10), comprises a pneumatic inlet (102) having a first line aperture, a mixing chamber (106) placed pneumatically downstream from the pneumatic inlet, at least a first gas injection port (108) having an inlet responsive to a mixing gas outlet of a mixing gas source and a mixing outlet that opens into the mixing chamber, and a pneumatic outlet (104) placed pneumatically downstream from the mixing chamber and having a second line aperture. The apparatus may further comprise a mixing gas source having a mixing gas outlet.
A high-throughput optical suspension characterization instrument is disclosed, which can include hydraulically separate and at least partially transparent sample containers. A selection mechanism is operative to selectively direct light from a light source (12) through different ones of the sample containers along an optical axis, and an off-axis scattering detector (38,24) is responsive to scattered light from the light source after it has interacted with a sample. Phase analysis light scattering is used to determine the electrophoretic mobility and zeta potential of samples. A second instrument is disclosed, wherein all sample containers are illuminated simultaneously. Transmitted light is collected by a camera. The electrophoretic mobility and hydrodynamic size of the samples may be determined.
G01N 21/25 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
G01N 21/51 - Dispersion, c. à d. réflexion diffuse dans un corps ou dans un fluide à l'intérieur d'un récipient, p.ex. dans une ampoule
A method for monitoring the heterogeneity of a sample comprises (i) collecting spectral signals from a plurality of sample regions during a first period, (ii) analysing the spectral signals collected during the first period to determine a statistical measure that is used to determine first information related to the chemical heterogeneity of the sample, (iii) collecting spectral signals from a plurality of sample regions during a second, later, period, (iv) analysing the spectral signals collected during the second period to determine a statistical measure that is used to determine second information related to the chemical heterogeneity of the sample, and (iv) using the first and second information related to the chemical heterogeneity of the sample to determine information related to changes in the chemical heterogeneity of the sample between the first and second time periods.
G01N 21/31 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique
G01N 21/85 - Analyse des fluides ou solides granulés en mouvement
In one general aspect, an instrument for measuring characteristics of particles suspended in a fluid is disclosed. It includes a closed wall surface defining a fractionation channel having a input opening, an output opening, and a flow axis that spans downstream from the input opening for the channel to the output opening. A force application subsystem has a force application output oriented perpendicular to at least part of the flow axis of the fractionation channel. A particle characteristic measurement subsystem is located hydraulically downstream from at least a portion of the closed wall surface defining the fractionation channel, and includes a sensor positioned to sense a property of the suspended particles in the potential measurement subsystem as well as a signal output responsive to the sensor. A result processor has a signal input responsive to the signal output of the particle characteristic measurement subsystem, zeta potential processing logic responsive to the particle characteristic measurement subsystem, and a particle characteristic signal output responsive to the particle characteristic processing logic.
In one general aspect, a multi-sample liquid scattering measurement apparatus is disclosed. It includes a coherent light source having an optical output axis, with sample cells that each include a volume that intersects with the optical output axis. Detectors are each positioned to detect scattered light resulting from an interaction between light from the coherent light source and one of the cells. Light scattering analysis logic is responsive to the detectors and operative to determine a property of a liquid sample in each of the sample cells based on the detected scattered light.
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c. à d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
38.
DYNAMIC LIGHT SCATTERING BASED MICRORHEOLOGY OF COMPLEX FLUIDS WITH IMPROVED SINGLE-SCATTERING MODE DETECTION
A fluid characterization measuring instrument comprises a sample vessel (14) for a bulk complex sample fluid having a capacity that is substantially larger than a domain size of the complex sample fluid and that is sufficiently large to cause bulk scattering effects to substantially exceed surface effects for the complex fluid sample, a coherent light source (12) positioned to illuminate the bulk complex sample fluid in the sample vessel and a first fibre (16) having a first end positioned to receive backscattered light from the sample after it has interacted with the sample. The first fibre is positioned close enough to an optical axis of the coherent light source and to the sample vessel to substantially decrease a contribution of multiply scattered light in the backscattered light. The instrument further comprises a first photon-counting detector (20) positioned to receive the backscattered light from a second end of the fibre, correlation logic (22) responsive to the first photon-counting detector and single-scattering fluid property analysis logic responsive to the correlation logic and operative to derive at least one fluid property for the sample fluid.
An apparatus for providing a light beam for use in a diffraction instrument (1) includes a device (10; 17; 28) for generating a light beam; and means (12, 21; 24) for shaping the light beam generated by the device (10; 17; 28), dimensioned, in use, to determine the beam shape, and including: an aperture (21; 25) and means (13; 24) for rejecting spatial frequency components above a certain range in the light beam. The apparatus further includes a spatial low-pass filter (14; 15; 26; 27) arranged to filter a beam provided by the beam shaping means.
G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c. à d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
In one general aspect, a method of measuring characteristics of particles in a liquid sample is disclosed. The method includes suspending the liquid sample in a tube. The suspended liquid sample is illuminated along an illumination axis, and at least a portion of the light is detected along a first detection axis after it is scattered by the particles in the suspended liquid sample. The illumination axis and the detection axis are oriented at an angle with respect to each other.
In one general aspect, a method of measuring characteristics of particles in a liquid sample disclosed. The method includes supporting the liquid sample by surface tension and illuminating the supported liquid sample along an illumination axis with spatially coherent light so as to cause the coherent light to be scattered across a scattering zone. At least a portion of the scattered light is detected along a first predetermined scattering detection axis after it is scattered by the particles in the supported liquid sample. The illumination axis and the detection axis are oriented at an angle with respect to each other that allows substantially all of the light scattered at that angle across the scattering zone to be detected.
A method of measuring characteristics of particles in a liquid sample, comprises suspending the liquid sample (10) in a capillary tube (40), illuminating the suspended liquid sample along an illumination axis (16), and detecting at least a portion of the light along a first detection axis (18B, 18F, 18S) after it is scattered by the particles in the suspended liquid sample, wherein the illumination axis (16) and the detection axis (18B,18F,18S) are oriented at an angle with respect to each other.
A method of measuring characteristics of particles in a liquid sample (10), comprises supporting the liquid sample by surface tension,illuminating the supported liquid sample along an illumination axis (16) with spatially coherent light so as to cause the coherent light to be scattered across a scattering zone, and detecting at least a portion of the scattered light along a first predetermined scattering detection axis (18) after it is scattered by the particles in the supported liquid sample, wherein the illumination axis (10) and the detection axis (18) are oriented at an angle with respect to each other that allows substantially all of the light scattered at that angle across the scattering zone to be detected.
A high-throughput optical suspension characterization instrument is disclosed, which can include hydraulically separate and at least partially transparent sample containers. A selection mechanism is operative to selectively direct light from a light source (12) through different ones of the sample containers along an optical axis, and an off -axis scattering detector (38,24) is responsive to scattered light from the light source after it has interacted with a sample. Phase analysis light scattering is used to determine the electrophoretic mobility and zeta potential of samples. A second instrument is disclosed, wherein all sample containers are illuminated simultaneously. Transmitted light is collected by a camera. The electrophoretic mobility and hydrodynamic size of the samples may be determined.
Rheometer for measuring properties of a sample is disclosed. It includes a first part having a drive portion operatively connected to an actuator and having a contact surface for contacting the sample (42). The rheometer also includes a second part that has another contact surface (46) for contacting the sample. A first heater (50) is positioned to heat the first part, a second heater (52) is positioned to heat the second part, and a heat pump (54) can heat and cool both the first and second parts.
G01N 11/14 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en déplaçant un corps à l'intérieur du matériau en utilisant des corps en rotation, p.ex. moulinet
G01N 11/16 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en déplaçant un corps à l'intérieur du matériau en mesurant l'effet d'amortissement sur un corps oscillant
46.
RHEOMETER WITH MODULAR ENVIRONMENTAL CONTROL SYSTEM
A rheometer uses a removable integrated environmental control cartridge that includes at least one environmental control unit, at least one supply port operative to interact with the supply port for a chassis of the rheometer. It also includes at least one mechanical alignment interface that isoperative to interact with the mechanical alignment interface of the chassis to align both the mobile part with respect to the fixed part and the chassis supply port with respect to the environmental control cartridge part. In another general aspect, a rheometer can use an environmental control cartridge interface operative to report an identity of the integrated environmental control cartridge to an environmental control cartridge identification interface of its chassis.
G01N 11/14 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en déplaçant un corps à l'intérieur du matériau en utilisant des corps en rotation, p.ex. moulinet
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
A rheometer is disclosed that includes rheometry logic that is responsive to a material selection control, to an objective selection control, to material property storage, and to process parameter storage, and is operative to assist the user with a measurement using the rheometer. In another general aspect, a rheometer includes sample history storage operative to store a history that spans a plurality of different operations performed bythe rheometer on a same sample.
G01N 11/14 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en déplaçant un corps à l'intérieur du matériau en utilisant des corps en rotation, p.ex. moulinet
B29C 35/02 - Chauffage ou durcissement, p.ex. réticulation ou vulcanisation
G01N 3/00 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique
G01N 3/06 - Adaptations particulières des moyens d'indication ou d'enregistrement
A rotary rheometer is disclosed that includes improved control logic. This logic can provide continuouslysampled force control logic, compliance control logic, adaptive control logic, anti-windup logic, and/or inertial correction logic.
G01N 11/14 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en déplaçant un corps à l'intérieur du matériau en utilisant des corps en rotation, p.ex. moulinet
49.
INSTRUMENT FOR DETERMINING A QUANTITY ASSOCIATED WITH A FORCE EXERTED ON A ROTOR
Rheometer, also usable for stress-strain- investigations, with at least one bearing (28; 35) having an adjustable stiffness in a direction normal to the bearing surfaces (19, 20, 21, 22, 23, 24, 26, 27). The instrument further includes a system (31, 32, 33, 34; 36, 37) for controlling a parameter for adjusting the stiffness of the at least one bearing (28; 35); a system (10) for determining a value of a quantity associated with a second force exerted between the rotor (8, 5, 6,7) and the stator (2) and opposing the force associated with the quantity to be determined; and a data processing system for correcting the determined value of the quantity associated with the second force by a bias value, obtained using a mapping having as a parameter a variable representative of the parameter for adjusting the stiffness.
G01N 3/24 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant des efforts permanents de cisaillement
G01N 3/38 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant des efforts répétés ou pulsatoires engendrés par des moyens électromagnétiques
G01N 11/14 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en déplaçant un corps à l'intérieur du matériau en utilisant des corps en rotation, p.ex. moulinet
F16C 32/06 - Paliers non prévus ailleurs comprenant un élément mobile supporté par un coussinet de fluide engendré, au moins en grande partie, autrement que par la rotation de l'arbre, p.ex. paliers hydrostatiques à coussinet d'air
G01L 5/12 - Appareils ou procédés pour la mesure des forces, du travail, de la puissance mécanique ou du couple, spécialement adaptés à des fins spécifiques pour la mesure de la poussée axiale d'un arbre tournant, p.ex. matériel de propulsion
50.
LIGHT SCATTERING MEASUREMENTS USING SIMULTANEOUS DETECTION
Methods and apparatus for measuring particle characteristics are disclosed. In one aspect, an amount of light arising from interaction between light and a suspended sample is detected simultaneously with the acquisition of a photon count from a different direction. At least one measure of particle characteristics can then be derived based at least in part on timing between information from the steps of acquiring and detecting.
In one general aspect, a particle characterization instrument is disclosed that includes a first spatially coherent light source with a beam output aligned with an optical axis. A focusing optic is positioned along the optical axis after the coherent light source, and a sample cell is positioned along the optical axis after the focusing optic. The instrument also includes a diverging optic positioned along the optical axis after the sample cell, and a detector positioned outside of the optical axis to receive scattered light within a first range of scattering angles from the diverging optic. In another general aspect, an instrument can direct at least a portion of a first beam and at least a portion of a second beam along a same optical axis and a can receive scattered light from the sample cell resulting from interaction between the sample and either the first beam or the second beam.
G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c. à d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
52.
Spectrometric characterization of pharmaceutical heterogeneity
In one general aspect, a spectroscopic method for monitoring heterogeneity of a sample is disclosed. In this method, sampled spectroscopic measurements are acquired over a range of different micro locations in a macro-sample of the sample. This step is repeated for micro-locations in further macro-samples of the sample, and a statistical measure of chemical heterogeneity is derived from the acquisitions. In another general aspect, differently sized samples are acquired, and a statistical measure of chemical heterogeneity is derived from these acquisitions.
An apparatus for providing a light beam for use in a diffraction instrument (1) includes a device (10; 17; 28) for generating a light beam; and means (12, 21; 24) for shaping the light beam generated by the device (10; 17; 28), dimensioned, in use, to determine the beam shape, and including: an aperture (21; 25) and means (13; 24) for rejecting spatial frequency components above a certain range in the light beam. The apparatus further includes a spatial low-pass filter (14, 15; 26, 27) arranged to filter a beam provided by the beam shaping means.
An apparatus for dispersing a sample of particulate material, includes a carrier (31; 35; 37; 38; 39) having a sample- bearing surface on which to place the sample, and a housing (10; 44; 48) for forming a dispersion chamber (17), at least when closed off at a base (46; 51). The carrier is arranged such that the sample-bearing surface is removed from contact with the sample upon application of a sufficient pressure differential across the carrier between the sample-bearing surface and an opposite side of the carrier. The housing (10; 44; 48) has an inlet (26) at least partially facing the base (46; 51). The apparatus includes an apparatus (15; 16) for passing a volume of fluid past the carrier (31; 35; 37; 38; 39) through the inlet (26) by subjecting the carrier (31; 35; 37; 38; 39) to a pulsed positive pressure differential relative to the dispersion chamber (17).
In one general aspect, a spectroscopic apparatus is disclosed for investigating heterogeneity of a sample area. The apparatus includes an image acquisition system operative to acquire images of a plurality of sub-areas in the sample area and a sub-area selection interface operative to receive a selection designating one of the sub-areas for which an image has been obtained. A spectrometer has a field of view and is operative to acquire a spectrum of at least part of one of the sub-areas in its field of view, and a positioning mechanism is responsive to the sub-area selection interface and operative to position the field of view of the spectrometer relative to the sample area based on a received selection.
A dilution apparatus suitable for use with particles suspended in a fluid is described. The apparatus comprises a first batch diluter and a second continuous diluter. The first diluter comprises a vessel having at least one inlet, and an outlet, the at least one inlet being arranged to receive diluent so as to mix said sample with said diluent. The second diluter comprises a sample input, a diluent inlet and an output, the diluent input being arranged such that diluent entering the second diluter experiences a pressure drop. The pressure drop is sufficient to entrain at least a portion of diluted sample from the first diluter through the sample input. The outlet of the first diluter is arranged to be in communication with the input of the second diluter such that a sample that has been pre-diluted in the first diluter is arranged to be further diluted in the second diluter.
A dilution apparatus (102) suitable for use with particles suspended in a fluid is described. The apparatus (102) comprises a first batch diluter (106) and a second continuous diluter (108). The first diluter (106) comprises a vessel (110) having at least one inlet, and an outlet (116), the at least one inlet being arranged to receive diluent so as to mix said sample with said diluent. The second diluter (108) comprises a sample input (124), a diluent inlet (132) and an output (134), the diluent input being arranged such that diluent entering the second diluter experiences a pressure drop. The pressure drop is sufficient to entrain at least a portion of diluted sample from the first diluter (106) through the sample input (124). The outlet of the first diluter is arranged to be in communication with the input of the second diluter (108) such that a sample that has been pre-diluted in the first diluter is arranged to be further diluted in the second diluter.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Electrical, optical, [ rheological,] image analytical, [ acoustical, ultrasonic ] and/or laser scientific and laboratory instruments for particle identifying, sizing, counting, classifying, differentiating, and grading, for measuring particle [ speeds, mobility, and ] distribution, and for monitoring airborne or pneumatically carried particles in liquid or gases; particle analyzers for grading and measuring concentrations of accumulations of particles; absorption scattering instruments employing UV-vis-IR optical absorption, [ ultrasonic absorption, and turbidity monitoring, ] for measuring real time of particle properties, transmitters and receivers, ejectors, dryers, and separators; monitoring and control instruments for grading, namely,[ laser diffraction ] size grading; particle mobility measuring instruments, environmental monitoring instruments, [ pH measuring instruments;] instruments to determine the molecular weight of polymers, namely, air and liquid particle counters, photon correlation spectroscopy instruments, micro electrophoresis measuring instruments, acoustic spectroscopy instruments, laser diffraction measuring instruments, all for use in clinical, biological, industrial, medical, academic and/or scientific research and commercial laboratories; [ diffraction measuring apparatus and instruments, namely, particle size, shape, and composition distribution analysers; sedimentation, sieve, diffraction, and zeta potential laboratory instruments;] apparatus for preparing samples, suspensions, sprays, emulsions of particles for use with any of the aforesaid goods, namely, sample dispersion units, stirred cells, autosamplers, dry powder feeders, autotitrators, nebulizers, ultrasonic baths, temperature controllers, sample grabbers, extractors, fluidisers, dispensers, diluters, concentrators, separators, dispersion units, measurement cells, auto-sampling units, automated preparation stages; control systems, namely, electrical controllers, computer hardware and computer software for controlling all of the aforesaid goods and for controlling copier and powder quality; replacement parts for the aforesaid goods
09 - Appareils et instruments scientifiques et électriques
Produits et services
Electrical, optical, acoustical, ultrasonic and/or laser scientific and laboratory instruments for counting, sizing, classifying, differentiating, and identifying particles in liquid or gases, for use in clinical, biological, industrial, medical, academic and/or scientific research and commercial laboratories, namely, particle size distribution and concentration measuring instruments, [ particle counting instruments, zeta potential measuring instruments, electrophoresis mobility measuring instruments, particle mobility measuring instruments, environmental temperature and humidity monitoring instruments, pH measuring instruments; instruments for producing zimm plots to determine the molecular weight of polymers namely, air and liquid particle counters, photocorrelation spectroscopy instruments, micro electrophoresis measuring instruments, acoustic spectroscopy instruments, ] laser diffraction measuring instruments, all for use in clinical, biological, industrial, medical, academic and/or scientific research and commercial laboratories; apparatus for preparing samples, suspensions, sprays, and emulsions of particles for use with any of the aforesaid goods, namely, sample dispersion units, stirred cells, autosamplers, dry powder feeders, dispensers, autotitrators, [ nebulizers, ] ultrasonic baths, and temperature controllers; [ computer and microprocessors, computer printers, ] computer software for controlling and operating all of the aforesaid goods; machine readable data carriers, [ namely, floppy discs, CD ROMs, optical discs, magnetic tapes, all ] packaged as a unit pre-programmed with control or analysis programs for use with the foregoing goods
