Disclosed are novel extracts, compositions, and methods with Bacillus subtilis probiotic compounds for countering multidrug-resistant (MDR) pathogens, such as Staphylococcus aureus, including anti-biofilm, anti-bacterial, and anti-quorum sensing for MDR pathogens.
An image-based hemoglobin estimation tool for measuring hemoglobin can be embedded in handheld devices such as smartphones, and similar known and to be developed technology. The hand-held device acquires video data of a finger illuminated from the dorsal surface by a first near infrared light responsive to hemoglobin and a second near infrared light near responsive to plasma. The acquired video is segmented into frames and processed to produce a Photoplethysmography (PPG) waveform. The features of the PPG waveform can then be identified, and the waveform and corresponding features evaluated by a predictive hemoglobin model. The predictive hemoglobin model can be provided at a remote computer, enabling non-invasive hemoglobin analysis from point of care locations. Near infrared lights of 850 nm and 1070 nm are particularly effective in the process.
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
The Board of Trustees of the Leland Stanford Junior University (USA)
Inventeur(s)
Gilat-Schmidt, Tal
Grönberg, Fredrik
Sjölin, Martin
Fan, Jiahua
Thomsen, Brian W.
Thibault, Jean-Baptiste
Hsieh, Jiang
Danielsson, Mats
Yang, Yirong
Pelc, Norbert J.
Wang, Adam S.
Abrégé
Methods and systems are provided for downsampling detector data in a computed tomography imaging system. In an example, a method for a photon counting computed tomography (PCCT) system includes, during a scan of an imaging subject, obtaining detector data from a photon counting detector of the PCCT system, the detector data comprising, for each pixel or detector element of the photon counting detector, photon counts partitioned into a plurality of energy bins based on an energy imparted by each photon on the photon counting detector, applying a bin factor to the plurality of energy bins for each pixel to downsample the plurality of energy bins into a reduced number of energy bins, and reconstructing one or more images from the reduced number of energy bins.
A61B 6/42 - Agencements pour détecter des radiations spécialement adaptés au diagnostic par radiations
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A scaffold for bone-tissue engineering includes a mesh and a coating on the mesh. The mesh includes a plurality of offset layers of filaments of polyester. The coating covers the mesh and includes magnesium hydroxide/copper oxide nanoparticles suspended in gelatin. A method of constructing the scaffold comprises combining magnesium hydroxide/copper oxide nanoparticles with a gelatin solution and coating a polyester mesh with the combined magnesium hydroxide/copper oxide nanoparticle and gelatin solution.
A61L 27/40 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
Disclosed are 4-hydroxylphenyl substituted carbocycles and there use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as pharmaceutical compositions and administered to treat diseases associated with ER activity, such as proliferative diseases and disorders and/or psychiatric diseases or disorders.
C07C 39/17 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques sans autre insaturation que celle des cycles aromatiques contenant d'autres cycles en plus des cycles aromatiques à six chaînons
A61K 31/047 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates ayant plusieurs groupes hydroxyle, p. ex. sorbitol
C07C 39/14 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques sans autre insaturation que celle des cycles aromatiques avec au moins un groupe hydroxyle lié à un système cyclique à deux cycles condensés
6.
IMAGE CYTOMETRY-BASED NON-INVASIVE WHITE BLOOD CELL COUNT FROM FINGERTIP VIDEOS
Systems and methods for non-invasivc measurement of white blood cell (WBC) count acquire a plurality of images with a camera. A light source illuminates the target while a magnetic applies a magnetic field to the target. A processor receives the plurality of images. The processor is configured to extract at least one image attribute from each image of the plurality of images and apply a K-means clustering technique to the extracted image attributes to classify the plurality of images. The processor is configured to calculate a WBC rate from the classified images and use a cardiac output with the WBC rate to calculate the WBC count.
G01N 33/80 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir les groupes ou les types sanguins
G06F 18/23213 - Techniques non hiérarchiques en utilisant les statistiques ou l'optimisation des fonctions, p. ex. modélisation des fonctions de densité de probabilité avec un nombre fixe de partitions, p. ex. K-moyennes
G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
7.
Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation
Disclosed are substituted (4′-hydroxylphenyl) cycloalkane compounds and substituted (4′-hydroxylphenyl) cycloalkene compounds and there use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as pharmaceutical compositions and administered for treating diseases associated with ER activity, such as neurological, psychiatric, and/or cell proliferative diseases and disorders as well as for enhancing memory consolidation in subjects in need thereof.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
C07C 35/21 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle autre qu'un cycle aromatique à six chaînons polycycliques, avec au moins un groupe hydroxyle lié à un cycle non condensé
8.
Process for Controlled Adsorption and Desorption of Phosphate From Liquids Using Phosphate-Selective Proteins
The present invention provides systems and methods for concentrating and recovering phosphate from samples. The method comprises using immobilized PBP for binding phosphate and a desorption solution having a pH of 11 or greater to recover phosphate from a sample when the phosphate is found at very low detection levels. Further systems and method for removing arsenate for water sources is also provided.
C02F 103/34 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter provenant de l'industrie chimique non prévue dans les groupes
C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions
G01N 30/00 - Recherche ou analyse de matériaux par séparation en constituants utilisant l'adsorption, l'absorption ou des phénomènes similaires ou utilisant l'échange d'ions, p. ex. la chromatographie
An electrical machine includes a stator comprising a plurality of windings, each of the windings comprising a first plurality of legs connected to a second plurality of legs to form a coil configuration, each of the legs in the first plurality of legs and each of the legs in the second plurality of legs comprising a duct extending from a first end to a second end of a length portion of the leg; a rotor including a plurality of permanent magnets; and power electronics, the power electronics providing an AC power supply to the stator causing the rotor to rotate. A fluid cooled chamber extends between the power electronics and the stator, the fluid cooled chamber comprising a plurality of heat pipes coupled the stator and/or the power electronics.
H02K 3/24 - Enroulements caractérisés par la configuration, la forme ou le genre de construction du conducteur, p. ex. avec des conducteurs en barre avec des canaux ou des conduits pour un agent de refroidissement entre les conducteurs
H02K 9/10 - Dispositions de refroidissement ou de ventilation par un agent de refroidissement gazeux circulant en circuit fermé, dont une partie est à l'extérieur de l'enveloppe de la machine
H02K 9/19 - Dispositions de refroidissement ou de ventilation pour machines avec enveloppe fermée et circuit fermé de refroidissement utilisant un agent de refroidissement liquide, p. ex. de l'huile
H02K 9/20 - Dispositions de refroidissement ou de ventilation pour machines avec enveloppe fermée et circuit fermé de refroidissement utilisant un agent de refroidissement liquide, p. ex. de l'huile dans lesquels l'agent de refroidissement se vaporise dans l'enveloppe de la machine
H02K 3/22 - Enroulements caractérisés par la configuration, la forme ou le genre de construction du conducteur, p. ex. avec des conducteurs en barre formés de conducteurs creux
H02K 9/02 - Dispositions de refroidissement ou de ventilation par l'air ambiant s'écoulant à travers la machine
H02K 9/08 - Dispositions de refroidissement ou de ventilation par un agent de refroidissement gazeux circulant entièrement à l'intérieur de l'enveloppe de la machine
H02K 9/197 - Dispositions de refroidissement ou de ventilation pour machines avec enveloppe fermée et circuit fermé de refroidissement utilisant un agent de refroidissement liquide, p. ex. de l'huile dans lesquels l'espace du rotor ou du stator est étanche au fluide, p. ex. pour pourvoir le rotor et le stator d'agents de refroidissement différents
10.
SYSTEMS, METHODS, AND MEDIA FOR MULTIMODAL DATA COLLECTION AND ANALYSIS FOR CANCER SCREENING
In some embodiments, a system for cervical cancer diagnosis is provided, the system comprising: a display; a fluorescence imaging (FLI) subsystem; a diffuse reflectance spectroscopy (DRS) subsystem; a first camera optically coupled to the FLI subsystem; a second camera optically coupled to the DRS subsystem; a processor configured to: receive patient history data; receive FLI image data; receive DRS image data; determine, based on the patient history data, a first cancer diagnosis determination; determine, based on the FLI image data, a second cancer diagnosis determination; extract features from the DRS image data; provide the features to a trained machine learning model trained to predict a tissue optical property based on DRS data; determine, based on a predicted optical property received from the model, a third cancer diagnosis determination; determine a cancer diagnosis based on the first, second, and third cancer diagnosis determinations; and visually present the cancer diagnosis.
A resonator includes a body, the body having a planar surface. An aperture through the body is configured to receive a tube configured for a fluid to be tested. A gap extends into the body from the planar surface to the aperture. At least one cut extends through the body from the planar surface towards the aperture. The at least one cut extends across the gap.
G01R 27/28 - Mesure de l'atténuation, du gain, du déphasage ou des caractéristiques qui en dérivent dans des réseaux électriques quadripoles, c.-à-d. des réseaux à double entréeMesure d'une réponse transitoire
G01N 1/04 - Dispositifs pour prélever des échantillons à l'état solide, p. ex. par coupe à l'outil
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (USA)
Inventeur(s)
Gilat-Schmidt, Tal
Grönberg, Fredrik
Sjölin, Martin
Fan, Jiahua
Thomsen, Brian, W.
Thibault, Jean-Baptiste
Hsieh, Jiang
Danielsson, Mats
Yang, Yirong
Pelc, Norbert
Wang, Adam, S.
Abrégé
Methods and systems are provided for downsampling detector data in a computed tomography imaging system. In an example, a method for a photon-counting computed tomography (PCCT) system includes, during a scan of an imaging subject, obtaining detector data from a photon-counting detector of the PCCT system, the detector data comprising, for each pixel or detector element of the photon-counting detector, photon counts partitioned into a plurality of energy bins based on an energy imparted by each photon on the photon-counting detector, applying a bin factor to the plurality of energy bins for each pixel to downsample the plurality of energy bins into a reduced number of energy bins, and reconstructing one or more images from the reduced number of energy bins.
G01N 23/046 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en transmettant la radiation à travers le matériau et formant des images des matériaux en utilisant la tomographie, p. ex. la tomographie informatisée
G01T 1/166 - Scintigraphie impliquant un mouvement relatif entre le détecteur et le sujet
G06T 5/10 - Amélioration ou restauration d'image utilisant le filtrage dans le domaine non spatial
Described here are systems and methods that utilize visual imagery and an optical flow-based computer vision algorithm to measure river velocity in streams or other flowing bodies of water. The systems and methods described in the present disclosure overcome the barriers of conventional flow measurement techniques by providing a fast, non-intrusive, remote method to measure peak flows.
G01C 13/00 - Géodésie spécialement adaptée à l'eau libre, p. ex. à la mer, aux lacs, aux rivières ou aux canaux
G01P 5/00 - Mesure de la vitesse des fluides, p. ex. d'un courant atmosphériqueMesure de la vitesse de corps, p. ex. navires, aéronefs, par rapport à des fluides
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Printed announcement cards; Envelopes; Printed note cards; Sealing stickers; Printed certificates; Return Address Labels Displays in the form of a frame for displaying diplomas Educational services, namely, providing courses at the university level featuring undergraduate and graduate education
17.
SYNTHESIS AND EVALUATION OF NOVEL (4-HYDROXYPHENYL) SUBSTITUTED CARBOCYCLES AS POTENT AND SELECTIVE ESTROGEN RECEPTOR BETA AGONISTS
Disclosed are 4-hydroxylphenyl substituted carbocycles and there use as selective agonists of the estrogen receptor beta isoform (ER?). The disclosed compounds may be formulated as pharmaceutical compositions and administered to treat diseases associated with ER activity, such as proliferative diseases and disorders and/or psychiatric diseases or disorders.
C07C 35/31 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle autre qu'un cycle aromatique à six chaînons polycycliques, avec au moins un groupe hydroxyle lié à un système cyclique condensé le groupe hydroxyle étant sur un système cyclique condensé à deux cycles le système cyclique condensé contenant huit atomes de carbone
C07C 35/21 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle autre qu'un cycle aromatique à six chaînons polycycliques, avec au moins un groupe hydroxyle lié à un cycle non condensé
C07C 35/23 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle autre qu'un cycle aromatique à six chaînons polycycliques, avec au moins un groupe hydroxyle lié à un système cyclique condensé le groupe hydroxyle étant sur un système cyclique condensé à deux cycles
18.
SYNTHESIS AND EVALUATION OF NOVEL (4-HYDROXYPHENYL) SUBSTITUTED CARBOCYCLES AS POTENT AND SELECTIVE ESTROGEN RECEPTOR BETA AGONISTS
Disclosed are 4-hydroxylphenyl substituted carbocycles and there use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as pharmaceutical compositions and administered to treat diseases associated with ER activity, such as proliferative diseases and disorders and/or psychiatric diseases or disorders.
An actuation system for preventing actuation of a base device upon a non-target substrate. The actuation system includes a detector configured to generate and transmit a profile signal of a test substrate. A processing unit is in communication with the detector and configured to receive the profile signal of the test substrate from the detector, the processing unit being configured to determine whether the profile signal of the test substrate corresponds to a profile signal of a target substrate, and to generate an actuation signal if the profile signal of the test substrate corresponds to the profile signal of the target substrate. An actuation unit is in communication with the processing unit and the base device, the actuation unit being configured to receive the actuation signal from the processing unit and to permit the base device to actuate when receiving the actuation signal.
B25C 1/00 - Outils tenus à la main pour clouerDispositifs d'alimentation en clous pour ces outils
B25C 1/04 - Outils tenus à la main pour clouerDispositifs d'alimentation en clous pour ces outils utilisant la pression d'un fluide
G01N 21/25 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
A multi-port converter includes a hybrid energy storage system (HESS) that provides a faster dynamic response to load changes than prior art systems, and enables either downsizing of the main energy storage system (ESS) to increase the life of the main ESS (e.g. energy battery), or retaining the same size ESS and increasing the range or life of the power source. The multi-port convertor can advantageously result in lower investment and maintenance costs, and can also advantageously provide a path for inputs to directly feed the load. All these benefits can be achieved while reducing the number of active switches and overall component count as compared to prior art systems.
H02M 1/00 - Détails d'appareils pour transformation
H02J 3/00 - Circuits pour réseaux principaux ou de distribution, à courant alternatif
H02J 3/32 - Dispositions pour l'équilibrage de charge dans un réseau par emmagasinage d'énergie utilisant des batteries avec moyens de conversion
H02J 3/38 - Dispositions pour l’alimentation en parallèle d’un seul réseau, par plusieurs générateurs, convertisseurs ou transformateurs
H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
H02J 7/34 - Fonctionnement en parallèle, dans des réseaux, de batteries avec d'autres sources à courant continu, p. ex. batterie tampon
H02M 3/158 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation comprenant plusieurs dispositifs à semi-conducteurs comme dispositifs de commande finale pour une charge unique
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
Disclosed herein are methods for treating wastewater grit to inactivate any pathogens that are present in the grit and for forming a solidified material comprising wastewater grit such as a chemically bonded phosphate ceramic (CBPC). The CBPC may be utilized in methods for repairing depressions in a road surface that include applying the uncured CBPC to the depression in the road surface and allowing the CBPC to cure.
C04B 35/622 - Procédés de mise en formeTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques
C04B 35/447 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base de phosphates
The present disclosure provides an apparatus comprising a primary treatment system configured to remove solids from an untreated fluid to generate a primary treated fluid. The apparatus further comprises an oxidation treatment system including an inlet configured to receive the primary treated fluid, an ozone inlet configured to receive ozone from an ozone generator, and an outlet configured to dispense secondary treated fluid. The apparatus may further comprise a controller in electrical communication with the ozone generator. The controller is programmed to regulate the flow of ozone through the oxidation treatment system such that an effective amount of ozone contacts the primary treated fluid to generate the secondary treated fluid. In some embodiments, the secondary treated fluid discharging from the oxidation treatment system has a chemical oxygen demand (COD) removal level of greater than 85%.
DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
MARQUETTE UNIVERSITY (USA)
Inventeur(s)
Park, Sang Hyun
Won, Dong Kyu
Ye, Dong Hye
Abrégé
An image processing method of the present disclosure may include receiving a scanned image, and processing the received image through an octave convolution-based neural network to output a high-quality image and an edge image for the received image. The octave convolution-based neural network may include a plurality of octave encoder blocks and a plurality of octave decoder blocks. Each octave encoder block may include an octave convolutional layer, and may be configured to output a high-frequency feature map and a low-frequency feature map for the image.
G06F 18/213 - Extraction de caractéristiques, p. ex. en transformant l'espace des caractéristiquesSynthétisationsMappages, p. ex. procédés de sous-espace
G06T 5/20 - Amélioration ou restauration d'image utilisant des opérateurs locaux
A stator winding includes a plurality of conductors including ducts. The ducts can be connected to a heat pipe or a conduit providing a coolant flow to directly cool the winding. The heat pipe can be connected to a heat exchanger that includes a coolant flow. The stator winding can be produced using additive manufacturing, with hollow ducts extending through leg sections and solid end sections. The heat exchanger can also be additively manufactured. A circuit for driving an electrical machine can be in thermal communication with the heat exchanger, such that the thermal system manages both the stators and the drive circuit.
H02K 3/24 - Enroulements caractérisés par la configuration, la forme ou le genre de construction du conducteur, p. ex. avec des conducteurs en barre avec des canaux ou des conduits pour un agent de refroidissement entre les conducteurs
H02K 3/28 - Schémas d'enroulements ou de connexions entre enroulements
H02K 3/48 - Fixation des enroulements sur la structure statorique ou rotorique dans les encoches
H02K 15/04 - Procédés ou appareils spécialement adaptés à la fabrication, l'assemblage, l'entretien ou la réparation des machines dynamo-électriques d'enroulements avant leur montage dans les machines
25.
Materials Based on Natural Pollen Grains and Uses Thereof
Disclosed herein are methods for preparing sporopollenin exine capsules (SECs) and methods for preparing composite materials that comprise SECs that utilize ionic liquid compositions. The composite materials typically include structural polymers and the SECs, and the SECs optionally may encapsulate useful materials, such as flame retardant materials, phase change materials, and therapeutic materials, such as probiotics and prebiotics. The composite materials may be prepared from ionic liquid compositions comprising the structural polymers and the SECs which optionally may encapsulate the useful materials, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials comprising the SECs. The composite materials may be used in applications include (1) wound dressings to cool down damaged tissue; (2) as textiles to regulate the body temperature; (3) in building materials to regulate building temperature; (3) to provide fire retardation in textile and building materials; and (4) to deliver and protect probiotics and prebiotics from acidic conditions and digestive enzymes in the stomach, so that they fully retain their biological activity in the guts.
C08L 5/00 - Compositions contenant des polysaccharides ou leurs dérivés non prévus dans les groupes ou
C04B 20/00 - Emploi de matières comme charges pour mortiers, béton ou pierre artificielle prévu dans plus d'un groupe et caractérisées par la forme ou la répartition des grainsTraitement de matières spécialement adapté pour renforcer leur propriétés de charge dans les mortiers, béton ou pierre artificielle prévu dans plus d'un groupe de Matières expansées ou défibrillées
D06M 23/12 - Procédés dans lesquels l'agent traitant est incorporé dans des microcapsules
26.
SELECTIVE TRANSITION METAL CATALYZED DEUTERIUM INCORPORATION INTO ALKYNE AND ALKENE FUNCTIONALITIES
Disclosed herein are deuterated compounds and transition metal catalyzed methods for making deuterated compounds. The disclosed methods are regioselective and enantioselective and may be utilized to prepare isomerically and/or enantiomerically pure or enriched deuterated compounds. The disclosed methods also may be modified in order to prepared fluorinated compounds.
C07C 67/38 - Préparation d'esters d'acides carboxyliques par réaction avec du monoxyde de carbone ou des formiates par addition à une liaison non saturée carbone-carbone
27.
SELECTIVE TRANSITION METAL CATALYZED DEUTERIUM INCORPORATION INTO ALKYNE AND ALKENE FUNCTIONALITIES
Disclosed herein are deuterated compounds and transition metal catalyzed methods for making deuterated compounds. The disclosed methods are regioselective and enantioselective and may be utilized to prepare isomerically and/or enantiomerically pure or enriched deuterated compounds. The disclosed methods also may be modified in order to prepared fluorinated compounds.
C07C 67/38 - Préparation d'esters d'acides carboxyliques par réaction avec du monoxyde de carbone ou des formiates par addition à une liaison non saturée carbone-carbone
28.
CONTINUOUS HEAVY METAL WATER CONTAMINANT MEASUREMENT SYSTEM
A resonator includes a body, the body having a planar surface. An aperture through the body is configured to receive a tube configured for a fluid to be tested. A gap extends into the body from the planar surface to the aperture. At least one cut extends through the body from the planar surface towards the aperture. The at least one cut extends across the gap.
G01N 22/00 - Recherche ou analyse des matériaux par l'utilisation de micro-ondes ou d'ondes radio, c.-à-d. d'ondes électromagnétiques d'une longueur d'onde d'un millimètre ou plus
A resonator includes a body, the body having a planar surface. An aperture through the body is configured to receive a tube configured for a fluid to be tested. A gap extends into the body from the planar surface to the aperture. At least one cut extends through the body from the planar surface towards the aperture. The at least one cut extends across the gap.
G01N 22/00 - Recherche ou analyse des matériaux par l'utilisation de micro-ondes ou d'ondes radio, c.-à-d. d'ondes électromagnétiques d'une longueur d'onde d'un millimètre ou plus
Scaffolds for use in bone tissue engineering include a skeleton and a host component. Methods of preparation of scaffolds include identification of biodegradation properties for the skeleton and the host component. The skeleton is constructed to form a three-dimensional shape. The skeleton is constructed of a first material and has a first rate of biodegradation. The host component fills the three-dimensional shape formed by the skeleton. The host component is constructed of a second material and has a second rate of biodegradation. The first rate of biodegradation is slower than the second rate of biodegradation.
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/42 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice inorganique
A61L 27/46 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges inorganiques contenant du phosphore
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
The present disclosure provides an apparatus comprising a primary treatment system configured to remove solids from an untreated fluid to generate a primary treated fluid. The apparatus further comprises an oxidation treatment system including an inlet configured to receive the primary treated fluid, an ozone inlet configured to receive ozone from an ozone generator, and an outlet configured to dispense secondary treated fluid. The apparatus may further comprise a controller in electrical communication with the ozone generator. The controller is programmed to regulate the flow of ozone through the oxidation treatment system such that an effective amount of ozone contacts the primary treated fluid to generate the secondary treated fluid. In some embodiments, the secondary treated fluid discharging from the oxidation treatment system has a chemical oxygen demand (COD) removal level of greater than 85%.
The present disclosure provides an apparatus comprising a primary treatment system configured to remove solids from an untreated fluid to generate a primary treated fluid. The apparatus further comprises an oxidation treatment system including an inlet configured to receive the primary treated fluid, an ozone inlet configured to receive ozone from an ozone generator, and an outlet configured to dispense secondary treated fluid. The apparatus may further comprise a controller in electrical communication with the ozone generator. The controller is programmed to regulate the flow of ozone through the oxidation treatment system such that an effective amount of ozone contacts the primary treated fluid to generate the secondary treated fluid. In some embodiments, the secondary treated fluid discharging from the oxidation treatment system has a chemical oxygen demand (COD) removal level of greater than 85%.
Disclosed herein are processes, systems, and catalysts for improving pyrolysis technology. The disclosed processes and systems utilize a catalyst to increase pyrolysis gas (py-gas) and decrease bio-oil yields in pyrolysis reactions. The disclosed catalysts may include biochar derived from pyrolysis of industrial residuals, such as pyrolysis of wastewater biosolids (WB) and paper mill sludge (PMS). The disclosed catalysts also may include ash derived from incineration of wastewater biosolids (“biosolids incineration ash” (BIA)).
C10B 53/02 - Distillation destructive spécialement conçue pour des matières premières solides particulières ou sous forme spéciale de matières contenant de la cellulose
B01J 23/02 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe des métaux alcalins ou alcalino-terreux ou du béryllium
B01J 23/78 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe du cuivre ou des métaux du groupe du fer en combinaison avec des métaux, oxydes ou hydroxydes prévus dans les groupes avec des métaux alcalins ou alcalino-terreux ou du béryllium
B01J 27/185 - PhosphoreSes composés avec des métaux du groupe du fer ou avec des métaux du groupe du platine
B01J 27/186 - PhosphoreSes composés avec de l'arsenic, de l'antimoine, du bismuth, du vanadium, du niobium, du tantale, du polonium, du chrome, du molybdène, du tungstène, du manganèse, du technétium ou du rhénium
C02F 11/10 - Traitement des boues d'égoutDispositifs à cet effet par pyrolyse
C10G 1/08 - Production de mélanges liquides d'hydrocarbures à partir de schiste bitumineux, de sable pétrolifère ou de matières carbonées solides non fusibles ou similaires, p. ex. bois, charbon par hydrogénation destructive avec catalyseurs mobiles
C10K 3/02 - Modification de la composition chimique des gaz combustibles contenant l'oxyde de carbone en vue de produire un carburant amélioré, p. ex. un carburant de pouvoir calorifique différent qui peut ne pas contenir d'oxyde de carbone par traitement catalytique
C10L 1/02 - Combustibles carbonés liquides à base essentielle de composants formés uniquement de carbone, d'hydrogène et d'oxygène
C10L 5/44 - Combustibles solides à base essentielle de matières d'origine non minérale de matières végétales
34.
SYSTEMS AND METHODS FOR REMOTE SENSING OF RIVER VELOCITY USING VIDEO AND AN OPTICAL FLOW ALGORITHM
Described here are systems and methods that utilize visual imagery and an optical flow-based computer vision algorithm to measure river velocity in streams or other flowing bodies of water. The systems and methods described in the present disclosure overcome the barriers of conventional flow measurement techniques by providing a fast, non-intrusive, remote method to measure peak flows.
G01B 21/18 - Dispositions pour la mesure ou leurs détails, où la technique de mesure n'est pas couverte par les autres groupes de la présente sous-classe, est non spécifiée ou est non significative pour mesurer la profondeur
G01F 1/00 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu
35.
SYSTEMS AND METHODS FOR REMOTE SENSING OF RIVER VELOCITY USING VIDEO AND AN OPTICAL FLOW ALGORITHM
Described here are systems and methods that utilize visual imagery and an optical flow-based computer vision algorithm to measure river velocity in streams or other flowing bodies of water. The systems and methods described in the present disclosure overcome the barriers of conventional flow measurement techniques by providing a fast, non-intrusive, remote method to measure peak flows.
G01B 21/18 - Dispositions pour la mesure ou leurs détails, où la technique de mesure n'est pas couverte par les autres groupes de la présente sous-classe, est non spécifiée ou est non significative pour mesurer la profondeur
G01F 1/00 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu
A multi -port converter includes a hybrid energy storage system (HESS) that provides a faster dynamic response to load changes than prior art systems, and enables either downsizing of the main energy storage system (ESS) to increase the life of the main ESS (e.g. energy battery), or retaining the same size ESS and increasing the range or life of the power source. The multi-port convertor can advantageously result in lower investment and maintenance costs, and can also advantageously provide a path for inputs to directly feed the load. All these benefits can be achieved while reducing the number of active switches and overall component count as compared to prior art systems.
H02M 7/00 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant continuTransformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif
H02M 3/00 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu
Disclosed herein are methods for treating wastewater grit to inactivate any pathogens that are present in the grit and for forming a solidified material comprising wastewater grit such as a chemically bonded phosphate ceramic (CBPC). The CBPC may be utilized in methods for repairing depressions in a road surface that include applying the uncured CBPC to the depression in the road surface and allowing the CBPC to cure.
C04B 28/34 - Compositions pour mortiers, béton ou pierre artificielle, contenant des liants inorganiques ou contenant le produit de réaction d'un liant inorganique et d'un liant organique, p. ex. contenant des ciments de polycarboxylates contenant des liants phosphate froids
E01C 23/09 - Dispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour former des gorges, des rainures ou des évidements, p. ex. pour former des joints ou des sillons pour le marquage, pour le découpage des sections à retirerDispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour nettoyer, traiter ou remplir des sillons, rainures, évidements ou fissuresDispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour rogner les bords du revêtement
C04B 103/60 - Agents de protection contre la dégradation chimique, physique ou biologique
C02F 1/52 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par floculation ou précipitation d'impuretés en suspension
Disclosed herein are methods for treating wastewater grit to inactivate any pathogens that are present in the grit and for forming a solidified material comprising wastewater grit such as a chemically bonded phosphate ceramic (CBPC). The CBPC may be utilized in methods for repairing depressions in a road surface that include applying the uncured CBPC to the depression in the road surface and allowing the CBPC to cure.
C04B 28/34 - Compositions pour mortiers, béton ou pierre artificielle, contenant des liants inorganiques ou contenant le produit de réaction d'un liant inorganique et d'un liant organique, p. ex. contenant des ciments de polycarboxylates contenant des liants phosphate froids
E01C 23/09 - Dispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour former des gorges, des rainures ou des évidements, p. ex. pour former des joints ou des sillons pour le marquage, pour le découpage des sections à retirerDispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour nettoyer, traiter ou remplir des sillons, rainures, évidements ou fissuresDispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour rogner les bords du revêtement
39.
Process for controlled adsorption and desorption of phosphate from liquids using phosphate-selective proteins
The present invention provides systems and methods for concentrating and recovering phosphate from samples. The method comprises using immobilized PBP for binding phosphate and a desorption solution having a pH of 11 or greater to recover phosphate from a sample when the phosphate is found at very low detection levels. Further systems and method for removing arsenate for water sources is also provided.
C02F 103/34 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter provenant de l'industrie chimique non prévue dans les groupes
C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions
G01N 30/00 - Recherche ou analyse de matériaux par séparation en constituants utilisant l'adsorption, l'absorption ou des phénomènes similaires ou utilisant l'échange d'ions, p. ex. la chromatographie
A stator winding includes a plurality of conductors including ducts. The ducts can be connected to a heat pipe or a conduit providing a coolant flow to directly cool the winding. The heat pipe can be connected to a heat exchanger that includes a coolant flow. The stator winding can be produced using additive manufacturing, with hollow ducts extending through leg sections and solid end sections. The heat exchanger can also be additively manufactured. A circuit for driving an electrical machine can be in thermal communication with the heat exchanger, such that the thermal system manages both the stators and the drive circuit.
H02K 3/04 - Enroulements caractérisés par la configuration, la forme ou le genre de construction du conducteur, p. ex. avec des conducteurs en barre
H02K 3/22 - Enroulements caractérisés par la configuration, la forme ou le genre de construction du conducteur, p. ex. avec des conducteurs en barre formés de conducteurs creux
H02K 3/24 - Enroulements caractérisés par la configuration, la forme ou le genre de construction du conducteur, p. ex. avec des conducteurs en barre avec des canaux ou des conduits pour un agent de refroidissement entre les conducteurs
H02K 3/26 - Enroulements caractérisés par la configuration, la forme ou le genre de construction du conducteur, p. ex. avec des conducteurs en barre constitués par des conducteurs imprimés
41.
Systems and components for anchoring objects to rack mount systems and assemblies
An anchoring device for securing objects within a rack mount system using fasteners. The anchoring device has a base portion with flush and anchor faces, the anchor faces defining apertures. Hooks are provided for securing the anchoring device to the rack mount system. Each hook has a horizontal arm with base and distal ends, and a vertical arm with upper and lower ends. Each base end is coupled to the anchor face and each distal end is coupled to the upper end of one vertical arm. Hooks are receivable within openings in the rack mount system to secure the anchoring device. The apertures in the base portion align with the openings in the rack mount system when the anchoring device is secured to the rack mount system such that the object is securable to the rack mount system by engaging the fasteners with the apertures in the anchoring device.
A47B 57/38 - Meubles à tiroirs, étagères ou rayonnages caractérisés par la possibilité de régler les rayons ou les cloisons comprenant des moyens pour régler la hauteur des supports de rayons amovibles consistant en pieds-droits du type à échelle comprenant des crochets sur les supports de rayons pour s'accrocher sur les échelons
Passive wireless sensors include an antenna. The antenna receives a combined signal. The combined signal includes a low frequency modulating signal modulated on a high frequency carrier wave. A demodulator receives the combined signal and extracts the modulating signal. A sensor receives the extracted modulating signal and produces an output signal with a time delay indicative of a property to be sensed. A modulator receives the output signal and the high frequency carrier wave and modulates the output signal onto the high frequency carrier wave to create a combined output signal broadcast by the antenna.
G01N 29/44 - Traitement du signal de réponse détecté
G01F 1/66 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu en mesurant la fréquence, le déphasage, le temps de propagation d'ondes électromagnétiques ou d'autres types d'ondes, p. ex. en utilisant des débitmètres à ultrasons
43.
Medical and dental integrated multiphasic biomaterials for single or multi-tissue reconstruction/regeneration
Disclosed herein are composite materials which may be used as biomedical materials or constructs. The disclosed biomedical materials or constructs may be multiphasic and typically provide a surface for cell growth. The disclosed biomedical materials and constructs typically comprise conjugable and/or adhesive chemical moieties, such as hydroxylated aromatic moieties, which facilitate integration of the components of the biomedical materials and constructs. Suitable hydroxylated aromatic moieties may include dihydroxybenzene (DHB) moieties, such as 1,2-DHB moeities, and derivatives thereof.
A61K 6/831 - Emploi d'éléments non métalliques ou de leurs composés, p. ex. de carbone
A61K 6/884 - Préparations pour la fabrication de dents artificielles, l’obturation ou le recouvrage des dents comprenant des résines naturelles ou synthétiques
A61L 27/26 - Mélanges de matériaux macromoléculaires
The present invention provides a stretchable hydrogel able to stretch over 200 times its length, methods of preparing such a hydrogel and compositions comprising the hydrogel.
A61B 5/318 - Modalités électriques se rapportant au cœur, p. ex. électrocardiographie [ECG]
A61L 15/22 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux macromoléculaires
A61L 26/00 - Aspects chimiques des bandages liquides ou utilisation de matériaux pour les bandages liquides
45.
Method and apparatus for non-invasive hemoglobin level prediction
An image-based hemoglobin estimation tool for measuring hemoglobin can be embedded in hand held devices such as smartphones, and similar known and to be developed technology. The hand-held device acquires video data of a finger illuminated from the dorsal surface by a first near infrared light responsive to hemoglobin and a second near infrared light near responsive to plasma. The acquired video is segmented into frames and processed to produce a Photoplethysmography (PPG) waveform. The features of the PPG waveform can then be identified, and the waveform and corresponding features evaluated by a predictive hemoglobin model. The predictive hemoglobin model can be provided at a remote computer, enabling non-invasive hemoglobin analysis from point of care locations. Near infrared lights of 850 nm and 1070 nm are particularly effective in the process.
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
46.
MATERIALS BASED ON NATURAL POLLEN GRAINS AND USES THEREOF
Disclosed herein are methods for preparing sporopollenin exine capsules (SECs) and methods for preparing composite materials that comprise SECs that utilize ionic liquid compositions. The composite materials typically include structural polymers and the SECs, and the SECs optionally may encapsulate useful materials, such as flame retardant materials, phase change materials, and therapeutic materials, such as probiotics and prebiotics. The composite materials may be prepared from ionic liquid compositions comprising the structural polymers and the SECs which optionally may encapsulate the useful materials, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials comprising the SECs. The composite materials may be used in applications include (1) wound dressings to cool down damaged tissue; (2) as textiles to regulate the body temperature; (3) in building materials to regulate building temperature; (3) to provide fire retardation in textile and building materials; and (4) to deliver and protect probiotics and prebiotics from acidic conditions and digestive enzymes in the stomach, so that they fully retain their biological activity in the guts.
Systems and methods of diagnosing open-circuit fault in power converters receives a neutral point current value, a switching state of the power converter, and load current values. At least one fault condition is identified based upon the switching state of the power converter and the load current values. The neutral point current value current value is compared to the at least one fault condition. An open circuit fault is determined to be present at the switching state of the power converter based upon the comparison.
H02M 7/537 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs, p. ex. onduleurs à impulsions à un seul commutateur
H02P 27/08 - Dispositions ou procédés pour la commande de moteurs à courant alternatif caractérisés par le type de tension d'alimentation utilisant une tension d’alimentation à fréquence variable, p. ex. tension d’alimentation d’onduleurs ou de convertisseurs utilisant des convertisseurs de courant continu en courant alternatif ou des onduleurs avec modulation de largeur d'impulsions
The present invention provides novel compounds with increased plasma stability that modulate PAR1 signaling, and methods of using them. The present invention provides methods of using the novel PAR1 modulators for the treatment of a number of disorders, including, inflammation, thrombosis, kidney disease, sepsis, stroke, as well as proliferation- related diseases. Furthermore, the PAR1 modulators of the present invention provide cytoprotection for certain cells and tissues, for example, in coronary blood vessels and tissues after a heart attack.
C07D 231/02 - Composés hétérocycliques contenant des cycles diazole-1, 2 ou diazole-1, 2 hydrogéné non condensés avec d'autres cycles
C07D 233/54 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, non condensés avec d'autres cycles comportant deux liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques
C07D 263/02 - Composés hétérocycliques contenant des cycles oxazole-1, 3 ou oxazole-1, 3 hydrogéné non condensés avec d'autres cycles
The present invention provides novel compounds with increased plasma stability that modulate PAR1 signaling, and methods of using them. The present invention provides methods of using the novel PAR1 modulators for the treatment of a number of disorders, including, inflammation, thrombosis, kidney disease, sepsis, stroke, as well as proliferation-related diseases. Furthermore, the PAR1 modulators of the present invention provide cytoprotection for certain cells and tissues, for example, in coronary blood vessels and tissues after a heart attack.
C07D 307/68 - Atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène
C07C 233/80 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone de cycles aromatiques à six chaînons ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un radical hydrocarboné substitué par des groupes amino avec le radical hydrocarboné substitué lié à l'atome d'azote du groupe carboxamide par un atome de carbone d'un cycle aromatique à six chaînons
C07C 233/66 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone de cycles aromatiques à six chaînons ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un radical hydrocarboné substitué par des atomes d'halogène ou par des groupes nitro ou nitroso
C07D 263/34 - Composés hétérocycliques contenant des cycles oxazole-1, 3 ou oxazole-1, 3 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des hétéro-atomes ou avec des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement aux atomes de carbone du cycle
C07D 277/587 - Composés hétérocycliques contenant des cycles thiazole-1, 3 ou thiazole-1, 3 hydrogénés non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des radicaux hydrocarbonés aliphatiques substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement aux atomes de carbone du cycle, lesdits radicaux aliphatiques étant substitués en position alpha du cycle par un hétéro-atome, p. ex. avec m ≥ 0, Z étant un hétéro-atome lié par une liaison simple ou double
C07D 233/90 - Atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
Split-crank pedaling devices and methods of operation support patient use and rehabilitation, particularly for stroke patients. A split-crank pedaling device includes first and second crank assemblies. First and second motors are operably connected to the first and second crank assemblies. A first shaft sensor produces an indication of a position of the shaft of the first crank assembly. A second shaft sensor produces an indication of a position of the shaft of the second crank assembly. A controller is communicatively connected to the first and second motors and the first and second shaft sensors and calculates a phase error between the positions of the first and second shafts and a predetermined phase relationship between the first and second shafts. The controller operates at least one of the first motor or the second motor to provide a supplemental torque to one of the first crank assembly and the second crank assembly.
A63B 23/035 - Appareils d'exercice spécialement adaptés à des parties déterminées du corps pour les membres, c.-à-d. supérieurs ou inférieurs, p. ex. en même temps
A61H 1/02 - Appareils d'exercice extenseurs ou de ployage
A63B 23/04 - Appareils d'exercice spécialement adaptés à des parties déterminées du corps pour les membres, c.-à-d. supérieurs ou inférieurs, p. ex. en même temps pour les membres inférieurs
A63B 22/06 - Appareils d'exercice spécialement adaptés à l'entraînement du système cardio-vasculaire, pour exercer l'agilité ou la coordination des mouvements avec un mouvement de pédalier
51.
Synthetic prosthesis for use in osteo-odonto-keratoprosthesis (OOKP) surgery
Disclosed herein is a prosthesis that may be used to replace standard prosthetic material used in osteo-odonto-keratoprosthesis (OOKP) surgery. The disclosed prosthesis is not prepared from tissue removed from a patient's tooth and jaw bone, but rather is a synthetic prosthesis. The synthetic prosthesis typically includes a solid part for supporting an optical cylinder and a porous part that facilitates bio-integration of the implanted prosthesis into the patient's eye.
A61L 27/12 - Matériaux contenant du phosphore, p. ex. apatite
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/40 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
52.
PROCESS FOR CONTROLLED ADSORPTION AND DESORPTION OF PHOSPHATE FROM LIQUIDS USING PHOSPHATE-SELECTIVE PROTEINS
The present invention provides systems and methods for concentrating and recovering phosphate from samples. The method comprises using immobilized PBP for binding phosphate and a desorption solution having a pH of 11 or greater to recover phospoate from a sample when the phosphate is found at very low detection levels.
C07K 17/14 - Peptides immobilisés sur, ou dans, un support inorganique
C12P 1/04 - Préparation de composés ou de compositions, non prévue dans les groupes , utilisant des micro-organismes ou des enzymesProcédés généraux de préparation de composés ou de compositions utilisant des micro-organismes ou des enzymes utilisant des bactéries
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
The present invention provides novel fluorinated analogs of fentanyl and methods of use. Specifically, the analogs of fentanyl can be used for the treatment of pain, including inflammation associated pain or chronic pain.
Disclosed are systems and methods of sensor fusion for exemplary use with robotic navigation control. Systems and methods include providing local estimates of a target location from a plurality of expert modules that process sensor data. The local estimates are weighted based upon a Mahalanobis distance from an expected estimated value and based upon a Euclidean distance between the local estimates. The local estimates are fused in a Bayesian fusion center based upon the weight given to each of the local estimates.
G05D 1/00 - Commande de la position, du cap, de l'altitude ou de l'attitude des véhicules terrestres, aquatiques, aériens ou spatiaux, p. ex. utilisant des pilotes automatiques
G05D 1/02 - Commande de la position ou du cap par référence à un système à deux dimensions
G06T 7/277 - Analyse du mouvement impliquant des approches stochastiques, p. ex. utilisant des filtres de Kalman
55.
ULTRA-HIGH STRETCHABLE HYDROGEL, METHODS OF MAKING AND USE
The present invention provides a stretchable hydrogel able to stretch over 200 times its length, methods of preparing such a hydrogel and compositions comprising the hydrogel.
A61L 27/40 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
A61L 31/12 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
B32B 27/06 - Produits stratifiés composés essentiellement de résine synthétique comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique
56.
METHOD AND APPARATUS FOR NON-INVASIVE HEMOGLOBIN LEVEL PREDICTION
An image-based hemoglobin estimation tool for measuring hemoglobin can be embedded in hand held devices such as smartphones, and similar known and to be developed technology. The hand-held device acquires video data of a finger illuminated from the dorsal surface by a first near infrared light responsive to hemoglobin and a second near infrared light near responsive to plasma. The acquired video is segmented into frames and processed to produce a Photoplethysmography (PPG) waveform. The features of the PPG waveform can then be identified, and the waveform and corresponding features evaluated by a predictive hemoglobin model. The predictive hemoglobin model can be provided at a remote computer, enabling non- invasive hemoglobin analysis from point of care locations. Near infrared lights of 850 nm and 1070 nm are particularly effective in the process.
A computer implemented method for selecting m appropriately sized meter tor use in a selected application implemented by a computer processor Implementing instructions stored in a non-transient memory is described. The instructions include receiving utility meter data transmitted from a plurality of utility meters, each utility meter being installed at a unique utility monitoring location, identifying incorrectly sized utility meters based on utility meter data for particular utility meters feat displays quantization effects, and selecting an appropriate meter based on the identification of the utility meters displaying quantization effects.
A computer implemented method for selecting m appropriately sized meter tor use in a selected application implemented by a computer processor Implementing instructions stored in a non-transient memory is described. The instructions include receiving utility meter data transmitted from a plurality of utility meters, each utility meter being installed at a unique utility monitoring location, identifying incorrectly sized utility meters based on utility meter data for particular utility meters feat displays quantization effects, and selecting an appropriate meter based on the identification of the utility meters displaying quantization effects.
An anchoring device for securing objects within a rack mount system using fasteners. The anchoring device has a base portion with flush and anchor faces, the anchor faces defining apertures. Hooks are provided for securing the anchoring device to the rack mount system. Each hook has a horizontal arm with base and distal ends, and a vertical arm with upper and lower ends. Each base end is coupled to the anchor face and each distal end is coupled to the upper end of one vertical arm. Hooks are receivable within openings in the rack mount system to secure the anchoring device. The apertures in the base portion align with the openings in the rack mount system when the anchoring device is secured to the rack mount system such that the object is securable to the rack mount system by engaging the fasteners with the apertures in the anchoring device.
Disclosed herein are methods and compositions for preserving avulsed teeth and/or explanted tissue. The disclosed methods for preserving avulsed teeth and/or explanted tissue typically include placing the avulsed teeth and/or explanted tissue in a preservation solution comprising at least about 2.75 g/L sugar. Suitable explanted tissues for the disclosed methods may include explanted tissues comprising fibroblasts, such as dental tissue and/or oral tissue. The preservation solution of the disclosed preservation methods may include additional components which may include but are not limited to inorganic salts, amino acids, vitamins, and buffering agents. The preservation solution may be prepared from a powder formulation having a long shelf-life.
Disclosed herein are composite materials, ionic liquid compositions for preparing the composite materials, and methods for using the composite materials prepared from the ionic liquid compositions. The composite materials typically include structural polymers and nitric oxide releasing agents, and preferably photo-reactive nitric oxide releasing compounds or complexes. The composite materials may be prepared from ionic liquid compositions comprising the structural polymers and the nitric oxide releasing agent, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials. The composite materials may be used in applications include dressing for wounds, where the nitric oxide releasing agents may be induced to release nitric oxide in order to inhibit microbial growth and promote healing.
A61L 15/46 - Désodorisants ou produits pour neutraliser les mauvaises odeurs, p. ex. pour inhiber la formation d'ammoniac ou la multiplication de bactéries
A61L 15/18 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux inorganiques
An ankle prosthesis comprises a foot prosthesis. A lower ankle is pivotably secured to the foot prosthesis at an ankle joint. An upper ankle is connected to the lower ankle in a manner that permits vertical movement of the upper ankle relative to the lower ankle. A coupling spring is biased in an extended condition. The coupling spring is connected at a first end to the upper ankle. A second end of the coupling spring is movable in a first condition which is engaged to the lower ankle and in a second condition engaged to the foot prosthesis. Energy is stored in compression of the coupling spring when the coupling spring is in the first condition and energy is released from the coupling spring when the coupling spring is in the second condition.
Scaffolds for use in bone tissue engineering include a skeleton and a host component. Methods of preparation of scaffolds include identification of biodegradation properties for the skeleton and the host component. The skeleton is constructed to form a three-dimensional shape. The skeleton is constructed of a first material and has a first rate of biodegradation. The host component fills the three-dimensional shape formed by the skeleton. The host component is constructed of a second material and has a second rate of biodegradation. The first rate of biodegradation is slower than the second rate of biodegradation.
A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/42 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice inorganique
A61L 27/46 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges inorganiques contenant du phosphore
A61L 27/48 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire avec des charges macromoléculaires
A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
Disclosed herein are composite materials, ionic liquid compositions for preparing the composite materials, and methods for using the composite materials prepared from the ionic liquid compositions. The composite materials typically include structural polysaccharides, structural proteins, and optionally including metal or metal oxide particles. The composite materials may be prepared from ionic liquid compositions comprising the structural polysaccharides, structural proteins, and the optional metal or metal oxide particles, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials.
A01N 43/16 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome des cycles à six chaînons avec l'oxygène comme hétéro-atome du cycle
A01N 37/18 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant le groupe —CO—N, p. ex. amides ou imides d'acide carboxyliqueLeurs thio-analogues
A61L 15/22 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux macromoléculaires
A61L 15/18 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux inorganiques
65.
SYSTEMS AND METHODS FOR RATING ASSET OWNER GOVERNANCE
Methods and systems for rating fiduciaries that govern assets. Governance variables relating to at least one of environmental and social factors for governing the assets that impact performance of the assets and related financial securities are collected. Control variables that also impact the performance are assigned. A collection of actual test values are compiled for the governance variables, the control variables, and the performance for test assets within the assets. A weight factor indicating the impacts on the performance by each of the governance variables and the control variables is assigned. A rating model incorporating the governance variables and the control variables and each respective weight factor is constructed. Actual asset values for the governance variables and the control variables for a given asset within the assets are collected. A given fiduciary within the fiduciaries that governs the given asset is rated using the rating model with the actual asset values collected.
A variable stiffness actuator comprises a flexure plate which comprises a first cantilevered beam that extends inwards from an outer periphery of the flexure plate. A housing and the flexure plate rotatable about a common joint axis. A first contactor is pivotably secured at a revolute joint to the housing. The first contactor rotates about the revolute joint at a first rotation axis. The first rotation axis offset on the housing from the joint axis. The first contactor engages the first cantilevered beam at a variable angle about the rotation axis to adjust a stiffness of a mechanical connection between the flexure plate and the housing.
An actuation system for preventing actuation of a base device upon a non-target substrate. The actuation system includes a detector configured to generate and transmit a profile signal of a test substrate. A processing unit is in communication with the detector and configured to receive the profile signal of the test substrate from the detector, the processing unit being configured to determine whether the profile signal of the test substrate corresponds to a profile signal of a target substrate, and to generate an actuation signal if the profile signal of the test substrate corresponds to the profile signal of the target substrate. An actuation unit is in communication with the processing unit and the base device, the actuation unit being configured to receive the actuation signal from the processing unit and to permit the base device to actuate when receiving the actuation signal.
B25C 1/00 - Outils tenus à la main pour clouerDispositifs d'alimentation en clous pour ces outils
B25C 1/04 - Outils tenus à la main pour clouerDispositifs d'alimentation en clous pour ces outils utilisant la pression d'un fluide
G01N 21/25 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
68.
Inertia-activated pulley motion and speed amplification of bristle belted rotary power tool
A device for processing a surface of a work piece. A motor is configured to produce a rotary force. A driving pulley is operatively coupled to the motor such that the rotary force produced by the motor causes rotation of the driving pulley. A belt is operatively coupled to the driving pulley such that rotation of the driving pulley causes rotation of the belt. A second pulley is also operatively coupled to the belt such that rotation of the belt causes rotation of the second pulley. Bristles are coupled to the belt and extend away from the belt. The rotary force produced by the motor causes the plurality of bristles to move relative to the motor. The surface of the work piece is processed when the bristles contacts the surface while the bristles are moving.
A46B 13/02 - Brosses à monture commandée à entraînement mécanique
B24B 29/00 - Machines ou dispositifs pour polir des surfaces de pièces au moyen d'outils en matière souple ou flexible avec ou sans application de produits de polissage solides ou liquides
B24D 13/10 - Meules dont le corps comporte des parties flexibles au travail, p. ex. meules souples de polissageAccessoires pour le montage de ces meules travaillant par leur périphérie comprenant des assemblages de brosses
B05D 3/12 - Traitement préalable des surfaces sur lesquelles des liquides ou d'autres matériaux fluides doivent être appliquésTraitement ultérieur des revêtements appliqués, p. ex. traitement intermédiaire d'un revêtement déjà appliqué, pour préparer les applications ultérieures de liquides ou d'autres matériaux fluides par des moyens mécaniques
A device for processing a surface of a work piece. A motor is configured to produce a rotary force. A driving pulley is operatively coupled to the motor such that the rotary force produced by the motor causes rotation of the driving pulley. A belt is operatively coupled to the driving pulley such that rotation of the driving pulley causes rotation of the belt. A second pulley is also operatively coupled to the belt such that rotation of the belt causes rotation of the second pulley. Bristles are coupled to the belt and extend away from the belt. The rotary force produced by the motor causes the plurality of bristles to move relative to the motor. The surface of the work piece is processed when the bristles contacts the surface while the bristles are moving.
B24B 23/06 - Machines de meulage portatives, p. ex. à guidage manuelAccessoires à cet effet avec des courroies abrasives, p. ex. avec des courroies sans finAccessoires à cet effet
B24B 21/12 - Machines ou dispositifs utilisant des bandes de meulage ou de polissageAccessoires à cet effet pour meuler des surfaces planes munis d'une roue de contact ou d'un tambour qui pousse la courroie contre la pièce à meuler
B24D 13/10 - Meules dont le corps comporte des parties flexibles au travail, p. ex. meules souples de polissageAccessoires pour le montage de ces meules travaillant par leur périphérie comprenant des assemblages de brosses
Split-crank pedaling devices and methods of operation support patient use and rehabilitation, particularly for stroke patients. A split-crank pedaling device includes first and second crank assemblies. First and second motors are operably connected to the first and second crank assemblies. A first shaft sensor produces an indication of a position of the shaft of the first crank assembly. A second shaft sensor produces an indication of a position of the shaft of the second crank assembly. A controller is communicatively connected to the first and second motors and the first and second shaft sensors and calculates a phase error between the positions of the first and second shafts and a predetermined phase relationship between the first and second shafts. The controller operates at least one of the first motor or the second motor to provide a supplemental torque to one of the first crank assembly and the second crank assembly.
A63B 22/06 - Appareils d'exercice spécialement adaptés à l'entraînement du système cardio-vasculaire, pour exercer l'agilité ou la coordination des mouvements avec un mouvement de pédalier
A63B 22/00 - Appareils d'exercice spécialement adaptés à l'entraînement du système cardio-vasculaire, pour exercer l'agilité ou la coordination des mouvements
Split-crank pedaling devices and methods of operation support patient use and rehabilitation, particularly for stroke patients. A split-crank pedaling device includes first and second crank assemblies. First and second motors are operably connected to the first and second crank assemblies. A first shaft sensor produces an indication of a position of the shaft of the first crank assembly. A second shaft sensor produces an indication of a position of the shaft of the second crank assembly. A controller is communicatively connected to the first and second motors and the first and second shaft sensors and calculates a phase error between the positions of the first and second shafts and a predetermined phase relationship between the first and second shafts. The controller operates at least one of the first motor or the second motor to provide a supplemental torque to one of the first crank assembly and the second crank assembly.
A63B 23/04 - Appareils d'exercice spécialement adaptés à des parties déterminées du corps pour les membres, c.-à-d. supérieurs ou inférieurs, p. ex. en même temps pour les membres inférieurs
72.
Fault-tolerant topology for multilevel T-type converters
Systems and methods of fault tolerant power conversion include an inverter with a plurality of inverter phase legs. Each phase leg includes a positive switch, a negative switch, and a bi-directional midpoint switch. Redundant phase leg includes a positive redundant switch connected between the positive switches and the bi-directional midpoint switches. The redundant phase leg includes a negative redundant switch connected between the negative switches and the bi-directional midpoint switches. Upon detection of a fault condition in at least one switch of the plurality of inverted phase legs, one of the positive redundant switch and the negative redundant switch is closed to bypass at least one switch with the fault condition to maintain operation of the power converter.
H02P 27/08 - Dispositions ou procédés pour la commande de moteurs à courant alternatif caractérisés par le type de tension d'alimentation utilisant une tension d’alimentation à fréquence variable, p. ex. tension d’alimentation d’onduleurs ou de convertisseurs utilisant des convertisseurs de courant continu en courant alternatif ou des onduleurs avec modulation de largeur d'impulsions
H02M 1/32 - Moyens pour protéger les convertisseurs autrement que par mise hors circuit automatique
H02P 29/032 - Prévention d’un endommagement du moteur, p. ex. détermination de limites individuelles de courant pour différentes conditions de fonctionnement
H02M 1/08 - Circuits spécialement adaptés à la production d'une tension de commande pour les dispositifs à semi-conducteurs incorporés dans des convertisseurs statiques
H02M 7/5395 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs, p. ex. onduleurs à impulsions à un seul commutateur avec commande automatique de la forme d'onde ou de la fréquence de sortie par modulation de largeur d'impulsions
H02P 29/028 - Détection d’un défaut, p. ex. court circuit, rotor bloqué, circuit ouvert ou perte de charge le moteur continuant de fonctionner malgré le défaut, p. ex. élimination, compensation ou résolution du défaut
H02M 1/00 - Détails d'appareils pour transformation
73.
MEDICAL AND DENTAL INTEGRATED MULTIPHASIC BIOMATERIALS FOR SINGLE OR MULTI-TISSUE RECONSTRUCTION/REGENERATION
Disclosed herein are composite materials which may be used as biomedical materials or constructs. The disclosed biomedical materials or constructs may be multiphasic and typically provide a surface for cell growth. The disclosed biomedical materials and constructs typically comprise conjugable and/or adhesive chemical moieties, such as hydroxylated aromatic moieties, which facilitate integration of the components of the biomedical materials and constructs. Suitable hydroxylated aromatic moieties may include dihydoxybenzene (DHB) moieties, such as 1,2-DHB moieities, and derivatives thereof.
Disclosed herein are composite materials which may be used as biomedical materials or constructs. The disclosed biomedical materials or constructs may be multiphasic and typically provide a surface for cell growth. The disclosed biomedical materials and constructs typically comprise conjugable and/or adhesive chemical moieties, such as hydroxylated aromatic moieties, which facilitate integration of the components of the biomedical materials and constructs. Suitable hydroxylated aromatic moieties may include dihydoxybenzene (DHB) moieties, such as 1,2-DHB moieities, and derivatives thereof.
SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE AND (4'-HYDROXYPHENYL)CYCLOALKENE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM FOR ENHANCED MEMORY CONSOLIDATION
Disclosed are substituted (4'-hydroxylphenyl)cycloalkane compounds and substituted (4'-hydroxylphenyl)cycloalkene compounds and there use as selective agonists of the estrogen receptor beta isoform (ERß). The disclosed compounds may be formulated as pharmaceutical compositions and administered for treating diseases associated with ER activity, such as neurological, psychiatric, and/or cell proliferative diseases and disorders as well as for enhancing memory consolidation in subjects in need thereof.
C07C 39/17 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques sans autre insaturation que celle des cycles aromatiques contenant d'autres cycles en plus des cycles aromatiques à six chaînons
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
C07C 39/23 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques contenant des cycles aromatiques à six chaînons et d'autres cycles avec une insaturation autre que celle des cycles aromatiques
C07D 311/00 - Composés hétérocycliques contenant des cycles à six chaînons comportant un atome d'oxygène comme unique hétéro-atome du cycle, condensés avec d'autres cycles
76.
SYNTHETIC PROSTHESIS FOR USE IN OSTEO-ODONTO-KERATOPROSTHESIS (OOKP) SURGERY
Disclosed herein is a prosthesis that may be used to replace standard prosthetic material used in osteo-odonto-keratoprosthesis (OOKP) surgery. The disclosed prosthesis is not prepared from tissue removed from a patient's tooth and jaw bone, but rather is a synthetic prosthesis. The synthetic prosthesis typically includes a solid part for supporting an optical cylinder and a porous part that facilitates bio-integration of the implanted prosthesis into the patient's eye.
A61F 2/14 - Parties d'yeux, p. ex. cristallins ou implants de cornéeYeux artificiels
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
77.
SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE AND (4'-HYDROXYPHENYL)CYCLOALKENE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM FOR ENHANCED MEMORY CONSOLIDATION
Disclosed are substituted (4'-hydroxylphenyl)cycloalkane compounds and substituted (4'-hydroxylphenyl)cycloalkene compounds and there use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as pharmaceutical compositions and administered for treating diseases associated with ER activity, such as neurological, psychiatric, and/or cell proliferative diseases and disorders as well as for enhancing memory consolidation in subjects in need thereof.
C07C 39/17 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques sans autre insaturation que celle des cycles aromatiques contenant d'autres cycles en plus des cycles aromatiques à six chaînons
C07D 311/00 - Composés hétérocycliques contenant des cycles à six chaînons comportant un atome d'oxygène comme unique hétéro-atome du cycle, condensés avec d'autres cycles
A61K 31/351 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle non condensés avec un autre cycle
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
78.
SYNTHETIC PROSTHESIS FOR USE IN OSTEO-ODONTO-KERATOPROSTHESIS (OOKP) SURGERY
Disclosed herein is a prosthesis that may be used to replace standard prosthetic material used in osteo-odonto-keratoprosthesis (OOKP) surgery. The disclosed prosthesis is not prepared from tissue removed from a patient's tooth and jaw bone, but rather is a synthetic prosthesis. The synthetic prosthesis typically includes a solid part for supporting an optical cylinder and a porous part that facilitates bio-integration of the implanted prosthesis into the patient's eye.
Disclosed are devices for controlling movement of an aerial bucket via a hydraulic system. The hydraulic system has a plurality of valves that control movement of the aerial bucket. A control head of the device has a joystick that is moveable and a plurality of encoders that detect movement of the joystick. A valve actuator manifold of the device is coupled between the control head and the hydraulic system and supports a plurality of valve actuators moveably coupled to the plurality of valves. A plurality of servo drive systems supported by the valve actuator manifold is coupled to the plurality of valve actuators and is controllable to move the plurality of valve actuators. A processor module of the device is in communication with the plurality of encoders and the plurality of servo drive systems. The processor module controls the plurality of servo drive systems based on input from the plurality of encoders such that moving the joystick controls movement of the aerial bucket.
B66F 11/04 - Dispositifs de levage spécialement adaptés à des buts particuliers, non prévus ailleurs pour plates-formes ou cabines mobiles, p. ex. sur des véhicules, permettant à des ouvriers d'occuper toute position convenable pour exécuter les travaux demandés
F15B 11/16 - Systèmes de servomoteurs dépourvus d'asservissement avec plusieurs servomoteurs
G06F 3/0338 - Dispositifs de pointage déplacés ou positionnés par l'utilisateurLeurs accessoires avec détection du déplacement linéaire ou angulaire limité d’une partie agissante du dispositif à partir d’une position neutre, p. ex. manches à balai isotoniques ou isométriques
Disclosed are systems and methods of sensor fusion for exemplary use with robotic navigation control. Systems and methods include providing local estimates of a target location from a plurality of expert modules that process sensor data. The local estimates are weighted based upon a Mahalanobis distance from an expected estimated value and based upon a Euclidean distance between the local estimates. The local estimates are fused in a Bayesian fusion center based upon the weight given to each of the local estimates.
G05D 1/00 - Commande de la position, du cap, de l'altitude ou de l'attitude des véhicules terrestres, aquatiques, aériens ou spatiaux, p. ex. utilisant des pilotes automatiques
81.
Shear horizontal-surface acoustic wave system and method for measurement and speciaion speciation of hydrocarbons in groundwater
An exemplary embodiment of a method of detecting hydrocarbons in Systems and methods for sensing analytes in an aqueous solution, include pretreating a water sample to provide a test sample. A flow cell includes at least one sensor with a polymer coating having at least partial selectivity for at least one analyte. The flow cell receives a test sample and a reference sample. At least one output signal from the at least one sensor is processed with a microcontroller using a model of the sensor response and a bank of Kalman filters to estimate a concentration of at least one analyte in the aqueous solution.
G01N 29/44 - Traitement du signal de réponse détecté
G01N 29/036 - Analyse de fluides en mesurant la fréquence ou la résonance des ondes acoustiques
G01N 29/22 - Recherche ou analyse des matériaux par l'emploi d'ondes ultrasonores, sonores ou infrasonoresVisualisation de l'intérieur d'objets par transmission d'ondes ultrasonores ou sonores à travers l'objet Détails
82.
STORAGE MEDIA AND POWDER FORMULATIONS FOR AVULSED TEETH AND EXPLANTED TISSUES COMPRISING FIBROBLASTS
Disclosed herein are methods and compositions for preserving avulsed teeth and/or explanted tissue. The disclosed methods for preserving avulsed teeth and/or explanted tissue typically include placing the avulsed teeth and/or explanted tissue in a preservation solution comprising at least about 2.75 g/L sugar. Suitable explanted tissues for the disclosed methods may include explanted tissues comprising fibroblasts, such as dental tissue and/or oral tissue. The preservation solution of the disclosed preservation methods may include additional components which may include but are not limited to inorganic salts, amino acids, vitamins, and buffering agents. The preservation solution may be prepared from a powder formulation having a long shelf-life.
Disclosed herein are methods and compositions for preserving avulsed teeth and/or explanted tissue. The disclosed methods for preserving avulsed teeth and/or explanted tissue typically include placing the avulsed teeth and/or explanted tissue in a preservation solution comprising at least about 2.75 g/L sugar. Suitable explanted tissues for the disclosed methods may include explanted tissues comprising fibroblasts, such as dental tissue and/or oral tissue. The preservation solution of the disclosed preservation methods may include additional components which may include but are not limited to inorganic salts, amino acids, vitamins, and buffering agents. The preservation solution may be prepared from a powder formulation having a long shelf-life.
Disclosed herein are composite materials, ionic liquid compositions for preparing the composite materials, and methods for using the composite materials prepared from the ionic liquid compositions. The composite materials typically include structural polymers and nitric oxide releasing agents, and preferably photo-reactive nitric oxide releasing compounds or complexes. The composite materials may be prepared from ionic liquid compositions comprising the structural polymers and the nitric oxide releasing agent, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials. The composite materials may be used in applications include dressing for wounds, where the nitric oxide releasing agents may be induced to release nitric oxide in order to inhibit microbial growth and promote healing.
A61L 15/18 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux inorganiques
Disclosed herein are composite materials, ionic liquid compositions for preparing the composite materials, and methods for using the composite materials prepared from the ionic liquid compositions. The composite materials typically include structural polymers and nitric oxide releasing agents, and preferably photo-reactive nitric oxide releasing compounds or complexes. The composite materials may be prepared from ionic liquid compositions comprising the structural polymers and the nitric oxide releasing agent, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials. The composite materials may be used in applications include dressing for wounds, where the nitric oxide releasing agents may be induced to release nitric oxide in order to inhibit microbial growth and promote healing.
A61L 15/18 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux inorganiques
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
A method of processing x-ray images comprises training an artificial neural network to process multi-spectral x-ray projections to determine composition information about an object in terms of equivalent thickness of at least one basis material. The method further comprises providing a multi-spectral x-ray projection of an object, wherein the multi-spectral x-ray projection of the object contains energy content information describing the energy content of the multi-spectral x-ray projection, The multi-spectral x-ray projection is then processed with the artificial neural network to determine composition information about the object, and then the composition information about the object is provided
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
Disclosed herein are processes, systems, and catalysts for improving pyrolysis technology. The disclosed processes and systems utilize a catalyst to increase pyrolysis gas (py-gas) and decrease bio-oil yields in pyrolysis reactions. The disclosed catalysts may include biochar derived from pyrolysis of industrial residuals, such as pyrolysis of wastewater biosolids (WB) and paper mill sludge (PMS). The disclosed catalysts also may include ash derived from incineration of wastewater biosolids ("biosolids incineration ash" (BIA)).
B01J 19/24 - Réacteurs fixes sans élément interne mobile
A62D 3/40 - Procédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances par chauffage pour effectuer une modification chimique, p. ex. par pyrolyse
C01B 32/05 - Préparation ou purification du carbone non couvertes par les groupes , , ,
B01J 23/70 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe du cuivre ou des métaux du groupe du fer
C01B 3/04 - Production d'hydrogène ou de mélanges gazeux contenant de l'hydrogène par décomposition de composés inorganiques, p. ex. de l'ammoniac
C02F 11/10 - Traitement des boues d'égoutDispositifs à cet effet par pyrolyse
C10G 1/02 - Production de mélanges liquides d'hydrocarbures à partir de schiste bitumineux, de sable pétrolifère ou de matières carbonées solides non fusibles ou similaires, p. ex. bois, charbon par distillation
Disclosed herein are processes, systems, and catalysts for improving pyrolysis technology. The disclosed processes and systems utilize a catalyst to increase pyrolysis gas (py-gas) and decrease bio-oil yields in pyrolysis reactions. The disclosed catalysts may include biochar derived from pyrolysis of industrial residuals, such as pyrolysis of wastewater biosolids (WB) and paper mill sludge (PMS). The disclosed catalysts also may include ash derived from incineration of wastewater biosolids ("biosolids incineration ash" (BIA)).
C02F 11/10 - Traitement des boues d'égoutDispositifs à cet effet par pyrolyse
C10L 5/46 - Combustibles solides à base essentielle de matières d'origine non minérale de boues d'égouts, d'ordures ménagères, de gadoues
C10K 3/02 - Modification de la composition chimique des gaz combustibles contenant l'oxyde de carbone en vue de produire un carburant amélioré, p. ex. un carburant de pouvoir calorifique différent qui peut ne pas contenir d'oxyde de carbone par traitement catalytique
Scaffolds for use in bone tissue engineering include a skeleton and a host component. Methods of preparation of scaffolds include identification of biodegradation properties for the skeleton and the host component. The skeleton is constructed to form a three- dimensional shape. The skeleton is constructed of a first material and has a first rate of biodegradation. The host component fills the three-dimensional shape formed by the skeleton. The host component is constructed of a second material and has a second rate of biodegradation. The first rate of biodegradation is slower than the second rate of biodegradation.
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61L 27/42 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice inorganique
A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
Scaffolds for use in bone tissue engineering include a skeleton and a host component. Methods of preparation of scaffolds include identification of biodegradation properties for the skeleton and the host component. The skeleton is constructed to form a three- dimensional shape. The skeleton is constructed of a first material and has a first rate of biodegradation. The host component fills the three-dimensional shape formed by the skeleton. The host component is constructed of a second material and has a second rate of biodegradation. The first rate of biodegradation is slower than the second rate of biodegradation.
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
A61L 27/42 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice inorganique
A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
An ankle prosthesis comprises a foot prosthesis. A lower ankle is pivotably secured to the foot prosthesis at an ankle joint. An upper ankle is connected to the lower ankle in a manner that permits vertical movement of the upper ankle relative to the lower ankle. A coupling spring is biased in an extended condition. The coupling spring is connected at a first end to the upper ankle. A second end of the coupling spring is movable in a first condition which is engaged to the lower ankle and in a second condition engaged to the foot prosthesis. Energy is stored in compression of the coupling spring when the coupling spring is in the first condition and energy is released from the coupling spring when the coupling spring is in the second condition.
An ankle prosthesis comprises a foot prosthesis. A lower ankle is pivotably secured to the foot prosthesis at an ankle joint. An upper ankle is connected to the lower ankle in a manner that permits vertical movement of the upper ankle relative to the lower ankle. A coupling spring is biased in an extended condition. The coupling spring is connected at a first end to the upper ankle. A second end of the coupling spring is movable in a first condition which is engaged to the lower ankle and in a second condition engaged to the foot prosthesis. Energy is stored in compression of the coupling spring when the coupling spring is in the first condition and energy is released from the coupling spring when the coupling spring is in the second condition.
A variable stiffness actuator comprises a flexure plate which comprises a first cantilevered beam that extends inwards from an outer periphery of the flexure plate. A housing and the flexure plate rotatable about a common joint axis. A first contactor is pivotably secured at a revolute joint to the housing. The first contactor rotates about the revolute joint at a first rotation axis. The first rotation axis offset on the housing from the joint axis. The first contactor engages the first cantilevered beam at a variable angle about the rotation axis to adjust a stiffness of a mechanical connection between the flexure plate and the housing.
Disclosed are systems, methods, and apparatuses to prevent actuation of a base device upon a non-target substrate. This invention is referred to as a smart trigger system in the present disclosure. The disclosed systems, methods, and apparatuses may include or utilize a detector generating a profile signal for a test substrate, a processing unit receiving the profile signal from the detector and determining whether the profile signal of the test substrate corresponds to a profile signal of a target substrate, and if so, generating an actuation signal. The disclosed systems, methods, and apparatuses may include or utilize an actuation unit which receives the actuation signal from the processing unit and permits the base device to actuate.
B25C 7/00 - Accessoires pour outils à clouer ou à agrafer, p. ex. supports
F16P 3/14 - Dispositifs de sécurité agissant en conjonction avec la commande ou le fonctionnement d'une machineCommandes exigeant l'emploi simultané de plusieurs parties du corps humain avec dispositifs, p. ex. des éléments sensibles, qui agissent sur la commande ou le fonctionnement de la machine lorsqu'une partie du corps humain se trouve dans ou près de la zone de danger les dispositifs étant des cellules photo-électriques ou d'autres dispositifs sensibles sans contact mécanique
Disclosed are systems, methods, and apparatuses to prevent actuation of a base device upon a non-target substrate. This invention is referred to as a smart trigger system in the present disclosure. The disclosed systems, methods, and apparatuses may include or utilize a detector generating a profile signal for a test substrate, a processing unit receiving the profile signal from the detector and determining whether the profile signal of the test substrate corresponds to a profile signal of a target substrate, and if so, generating an actuation signal. The disclosed systems, methods, and apparatuses may include or utilize an actuation unit which receives the actuation signal from the processing unit and permits the base device to actuate.
B25C 7/00 - Accessoires pour outils à clouer ou à agrafer, p. ex. supports
F16P 3/14 - Dispositifs de sécurité agissant en conjonction avec la commande ou le fonctionnement d'une machineCommandes exigeant l'emploi simultané de plusieurs parties du corps humain avec dispositifs, p. ex. des éléments sensibles, qui agissent sur la commande ou le fonctionnement de la machine lorsqu'une partie du corps humain se trouve dans ou près de la zone de danger les dispositifs étant des cellules photo-électriques ou d'autres dispositifs sensibles sans contact mécanique
A variable stiffness actuator comprises a flexure plate which comprises a first cantilevered beam that extends inwards from an outer periphery of the flexure plate. A housing and the flexure plate rotatable about a common joint axis. A first contactor is pivotably secured at a revolute joint to the housing. The first contactor rotates about the revolute joint at a first rotation axis. The first rotation axis offset on the housing from the joint axis. The first contactor engages the first cantilevered beam at a variable angle about the rotation axis to adjust a stiffness of a mechanical connection between the flexure plate and the housing.
Disclosed are fluorescent markers that include a known number of copies of a fluorescently-labeled protein regularly interspersed along the length of the fluorescent marker. The fluorescent markers may be used to quantify fluorescently-labeled samples in fluorescent microscopy.
Disclosed herein are composite materials, ionic liquid compositions for preparing the composite materials, and methods for using the composite materials prepared from the ionic liquid compositions. The composite materials typically include structural polysaccharides, structural proteins, and optionally including metal or metal oxide particles. The composite materials may be prepared from ionic liquid compositions comprising the structural polysaccharides, structural proteins, and the optional metal or metal oxide particles, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials.
C08J 3/09 - Production de solutions, dispersions, latex ou gel par d'autres procédés que ceux utilisant les techniques de polymérisation en solution, en émulsion ou en suspension dans des liquides organiques
Disclosed herein are composite materials, ionic liquid compositions for preparing the composite materials, and methods for using the composite materials prepared from the ionic liquid compositions. The composite materials typically include structural polysaccharides, structural proteins, and optionally including metal or metal oxide particles. The composite materials may be prepared from ionic liquid compositions comprising the structural polysaccharides, structural proteins, and the optional metal or metal oxide particles, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials.
C08J 3/09 - Production de solutions, dispersions, latex ou gel par d'autres procédés que ceux utilisant les techniques de polymérisation en solution, en émulsion ou en suspension dans des liquides organiques
Indoline sulfonamide compounds that can inhibit DapE and/or bacterial metallo-β-lactamases (MBLs), such as NDM-1, are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the indoline sulfonamide compounds disclosed herein.
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
C07D 209/10 - IndolesIndoles hydrogénés avec des radicaux hydrocarbonés substitués liés aux atomes de carbone de l'hétérocycle
C07D 209/08 - IndolesIndoles hydrogénés avec uniquement des atomes d'hydrogène ou des radicaux ne contenant que des atomes d'hydrogène et de carbone, liés directement aux atomes de carbone de l'hétérocycle
C07D 401/12 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
C07D 403/12 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons