Mileutis Ltd.

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Type PI
        Brevet 18
        Marque 12
Juridiction
        International 11
        États-Unis 10
        Canada 9
Date
2025 1
2024 3
2023 6
2022 3
Avant 2021 12
Classe IPC
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains 12
A61K 38/01 - Protéines hydrolyséesLeurs dérivés 10
A61K 38/07 - Tétrapeptides 7
A61K 38/08 - Peptides ayant de 5 à 11 amino-acides 6
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères 6
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Statut
En Instance 5
Enregistré / En vigueur 25

1.

USE OF COMPOSITION COMPRISING CASEIN HYDROLYSATE FOR THE TREATMENT OF INFLAMMATORY SKIN CONDITIONS

      
Numéro d'application IL2024050732
Numéro de publication 2025/022394
Statut Délivré - en vigueur
Date de dépôt 2024-07-24
Date de publication 2025-01-30
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Javier
  • Iscovich, Jose Mario

Abrégé

The present invention provides a method for preventing or treating inflammatory skin conditions, by administering a composition comprising at least one milk derived protein. The present invention further relates to a method for moisturizing dry skin, skin softening, reducing skin itching, reducing skin peeling, reducing skin redness, reducing rough skin, reducing skin swelling, reducing skin cracking, renewal skin cells, preserving hand skin or any combination thereof.

Classes IPC  ?

  • A61K 35/20 - LaitPetit-laitColostrum
  • A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
  • A61P 37/00 - Médicaments pour le traitement des troubles immunologiques ou allergiques
  • A61Q 19/00 - Préparations pour les soins de la peau

2.

ENHANCED MILK QUALITY

      
Numéro d'application IL2024050486
Numéro de publication 2024/236580
Statut Délivré - en vigueur
Date de dépôt 2024-05-16
Date de publication 2024-11-21
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abrégé

The current disclosure relates to a method of increasing milk quality in lactating mammals comprising administering a composition comprising at least one casein derived peptide.

Classes IPC  ?

  • A23C 9/00 - Préparations à base de laitLait en poudre ou préparations à base de lait en poudre
  • A23C 9/12 - Préparations à base de lait fermentéTraitements utilisant des micro-organismes ou des enzymes
  • A23C 9/142 - Préparations à base de laitLait en poudre ou préparations à base de lait en poudre dans lesquelles la composition chimique du lait est modifiée par des traitements non chimiques par dialyse, osmose inverse ou ultrafiltration
  • A23C 9/20 - Produits diététiques à base de lait non couverts par les groupes
  • A23C 19/05 - Traitement du lait avant le caillageSéparation du petit-lait du lait caillé
  • A23J 1/20 - Préparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir du lait, p. ex. caséinePréparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir du petit-lait
  • A23J 3/10 - Caséine
  • A23L 33/19 - Protéines du lait
  • A23L 33/00 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement
  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61K 38/07 - Tétrapeptides
  • A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • C07K 5/103 - Tétrapeptides la chaîne latérale du premier amino-acide étant acyclique, p. ex. Gly, Ala
  • C07K 5/11 - Tétrapeptides la chaîne latérale du premier amino-acide contenant plus de groupes amino que de groupes carboxyle, ou leurs dérivés, p. ex. Lys, Arg
  • C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
  • A23K 10/10 - Produits alimentaires pour animaux obtenus par des procédés microbiologiques ou biochimiques
  • A23K 10/20 - Produits alimentaires pour animaux à base de matières d’origine animale
  • A23K 20/147 - Dérivés polymériques, p. ex. peptides ou protéines
  • A23K 50/10 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les ruminants

3.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS

      
Numéro d'application 18557393
Statut En instance
Date de dépôt 2022-04-28
Date de la première publication 2024-06-27
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abrégé

The present disclosure provides compositions and methods for modulating various mammary' disorders and conditions. The disclosure further provides a therapeutic combination of a composition of at least one casein protein or casein-derived peptide; and a teat seal composition.

Classes IPC  ?

  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
  • A61K 33/245 - BismuthSes composés
  • A61K 38/07 - Tétrapeptides
  • A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
  • A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • A61K 47/44 - Huiles, graisses ou cires couvertes par plus d’un des groupes Huiles, graisses ou cires naturelles ou naturelles modifiées, p. ex. huile de ricin, huile de ricin polyéthoxylée, cire de lignite, lignite, gomme-laque, colophane, cire d’abeille ou lanoline

4.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS

      
Numéro d'application IL2023051181
Numéro de publication 2024/105668
Statut Délivré - en vigueur
Date de dépôt 2023-11-15
Date de publication 2024-05-23
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abrégé

The present invention provides compositions and methods for treating intramammary infection in lactating mammals during lactation and providing a continuous milk production and milking in lactating mammals during lactation, wherein somatic cell count in milk, milk electrical conductivity or combination thereof are increased.

Classes IPC  ?

  • A61K 35/20 - LaitPetit-laitColostrum
  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • A61K 38/38 - Albumines
  • A61K 38/40 - Transferrines, p. ex. lactoferrines, ovotransferrines
  • A61P 15/14 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs pour les troubles de la lactation, p. ex. galactorrhée

5.

Miscellaneous Design

      
Numéro d'application 1724571
Statut Enregistrée
Date de dépôt 2023-03-21
Date d'enregistrement 2023-03-21
Propriétaire MILEUTIS LTD (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

Intramammary and intrauterine veterinary preparations; intramammary and intrauterine pharmaceutical and medical preparations for human use; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections, and mammary disorders; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production; veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations, veterinary preparations and medical preparations for the involution of the udder or the mammary gland; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections, diseases, disorders and conditions in poultry, and for promoting growth or the welfare of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous system conditions; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of diseases, disorders and conditions of the skeletal system and the bones; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, or damages to the skin and tissues; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, or skin diseases, disorders and conditions related to hyperactive immune response, or allergic reactions and conditions; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of medical conditions and diseases associated with immunostimulation or immunomodulation; synthetic and biological peptides for the treatment of conditions and diseases associated with immunostimulation, or for immunomodulation; pharmaceutical, medical and veterinary preparations.

6.

MILEUTIS

      
Numéro d'application 1724572
Statut Enregistrée
Date de dépôt 2023-03-21
Date d'enregistrement 2023-03-21
Propriétaire MILEUTIS LTD (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

Intramammary and intrauterine veterinary preparations; intramammary and intrauterine pharmaceutical and medical preparations for human use; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections, and mammary disorders; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production; veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations, veterinary preparations and medical preparations for the involution of the udder or the mammary gland; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections, diseases, disorders and conditions in poultry, and for promoting growth or the welfare of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous system conditions; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of diseases, disorders and conditions of the skeletal system and the bones; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, or damages to the skin and tissues; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, or skin diseases, disorders and conditions related to hyperactive immune response, or allergic reactions and conditions; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of medical conditions and diseases associated with immunostimulation or immunomodulation; synthetic and biological peptides for the treatment of conditions and diseases associated with immunostimulation, or for immunomodulation; pharmaceutical, medical and veterinary preparations.

7.

Geometric Shape design

      
Numéro d'application 225177700
Statut En instance
Date de dépôt 2023-03-21
Propriétaire MILEUTIS LTD (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

(1) Intramammary and intrauterine veterinary preparations; intramammary and intrauterine pharmaceutical and medical preparations for human use; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections, and mammary disorders; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production; veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations, veterinary preparations and medical preparations for the involution of the udder or the mammary gland; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections, diseases, disorders and conditions in poultry, and for promoting growth or the welfare of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous system conditions; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of diseases, disorders and conditions of the skeletal system and the bones; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, or damages to the skin and tissues; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, or skin diseases, disorders and conditions related to hyperactive immune response, or allergic reactions and conditions; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of medical conditions and diseases associated with immunostimulation or immunomodulation; synthetic and biological peptides for the treatment of conditions and diseases associated with immunostimulation, or for immunomodulation; pharmaceutical, medical and veterinary preparations.

8.

MILEUTIS

      
Numéro d'application 225177800
Statut En instance
Date de dépôt 2023-03-21
Propriétaire MILEUTIS LTD (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

(1) Intramammary and intrauterine veterinary preparations; intramammary and intrauterine pharmaceutical and medical preparations for human use; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections, and mammary disorders; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production; veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations, veterinary preparations and medical preparations for the involution of the udder or the mammary gland; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections, diseases, disorders and conditions in poultry, and for promoting growth or the welfare of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous system conditions; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of diseases, disorders and conditions of the skeletal system and the bones; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, or damages to the skin and tissues; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, or skin diseases, disorders and conditions related to hyperactive immune response, or allergic reactions and conditions; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of medical conditions and diseases associated with immunostimulation or immunomodulation; synthetic and biological peptides for the treatment of conditions and diseases associated with immunostimulation, or for immunomodulation; pharmaceutical, medical and veterinary preparations.

9.

Miscellaneous Design

      
Numéro de série 79367537
Statut Enregistrée
Date de dépôt 2023-03-21
Date d'enregistrement 2025-01-07
Propriétaire MILEUTIS LTD (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

Intramammary and intrauterine veterinary preparations for treating mastitis, mammary infections, uterine infections, myometrium infection and intrauterine infections; intramammary and intrauterine pharmaceutical and medical preparations for human use for treating mastitis, mammary infections, and intrauterine infections; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections and mammary inflammation; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency, namely for treating gastro-intestinal diseases, anorexia, and for use as growth promoters; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production, namely for treating mastitis, mammary infections, and for involution of the mammary glands; veterinary preparations for the prevention and treatment of bacterial infections; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections; pharmaceutical preparations, veterinary preparations and medical preparations for mammary and udder involution; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count in milk, namely for treating mammary and udder inflammations; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals, namely for treating mammary pain, mammary infections, and edema; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions, namely for treating mammary pain, mammary infections, and edema; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections in poultry, and for use as growth promoters of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions, namely mucositis and buccal infections; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous systems diseases; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases; pharmaceutical and medical preparations for the prevention or treatment of diseases of the musculo-skeletal system; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, and damages to the skin and tissues, namely skin and tissue infections; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, and skin diseases, related to hyperactive immune response, or allergies; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of immunostimulation and immunomodulation; synthetic and biological peptides for the treatment of immunostimulation, and immunomodulation; pharmaceutical, medical and veterinary preparations to regulate and adapt the mammalian buccal, gastrointestinal and vaginal-vulvar microbiome for disease prevention and wellness

10.

MILEUTIS

      
Numéro de série 79367538
Statut Enregistrée
Date de dépôt 2023-03-21
Date d'enregistrement 2025-01-07
Propriétaire MILEUTIS LTD (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

Intramammary and intrauterine veterinary preparations for treating mastitis, mammary infections, uterine infections, myometrium infection and intrauterine infections; intramammary and intrauterine pharmaceutical and medical preparations for human use for treating mastitis, mammary infections, and intrauterine infections; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections and mammary inflammation; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency, namely for treating gastro-intestinal diseases, anorexia, and for use as growth promoters; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production, namely for treating mastitis, mammary infections, and for involution of the mammary glands; veterinary preparations for the prevention and treatment of bacterial infections; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections; pharmaceutical preparations, veterinary preparations and medical preparations for mammary and udder involution; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count in milk, namely for treating mammary and udder inflammations; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals, namely for treating mammary pain, mammary infections, and edema; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions, namely for treating mammary pain, mammary infections, and edema; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections in poultry, and for use as growth promoters of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions, namely mucositis and buccal infections; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous systems diseases; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases; pharmaceutical and medical preparations for the prevention or treatment of diseases of the musculo-skeletal system; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, and damages to the skin and tissues, namely skin and tissue infections; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, and skin diseases, related to hyperactive immune response, or allergies; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of immunostimulation and immunomodulation; synthetic and biological peptides for the treatment of immunostimulation, and immunomodulation; pharmaceutical, medical and veterinary preparations to regulate and adapt the mammalian buccal, gastrointestinal and vaginal-vulvar microbiome for disease prevention and wellness

11.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS

      
Numéro d'application IL2022050442
Numéro de publication 2022/229965
Statut Délivré - en vigueur
Date de dépôt 2022-04-28
Date de publication 2022-11-03
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abrégé

The present disclosure provides compositions and methods for modulating various mammary' disorders and conditions. The disclosure further provides a therapeutic combination of a composition of at least one casein protein or casein-derived peptide; and a teat seal composition.

Classes IPC  ?

  • A61K 38/07 - Tétrapeptides
  • A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • A61K 31/29 - Composés de l'antimoine ou du bismuth
  • C07K 5/10 - Tétrapeptides
  • C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
  • A61P 15/14 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs pour les troubles de la lactation, p. ex. galactorrhée
  • A61P 31/04 - Agents antibactériens

12.

IMILAC

      
Numéro d'application 221151500
Statut Enregistrée
Date de dépôt 2022-09-01
Date d'enregistrement 2025-05-02
Propriétaire Mileutis Ltd. (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

(1) Veterinary preparations for use in livestock for the prevention and treatment of mastitis and mammary infections; veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; animal production efficiency enhancing veterinary preparations to aid in milk production in lactating animals and improving feed efficiency; veterinary preparations for the prevention and treatment of intramammary infections; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for shortening the dry-off period in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in livestock

13.

MILAC

      
Numéro d'application 221151600
Statut Enregistrée
Date de dépôt 2022-09-01
Date d'enregistrement 2025-05-02
Propriétaire Mileutis Ltd. (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

(1) Veterinary preparations for use in livestock for the prevention and treatment of mastitis and mammary infections; veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; veterinary preparations for the prevention and treatment of intramammary infections; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms related to infections in livestock during the lactation period

14.

IMILAC

      
Numéro d'application 1568067
Statut Enregistrée
Date de dépôt 2020-05-21
Date d'enregistrement 2020-05-21
Propriétaire Mileutis Ltd. (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

Veterinary products, namely, preparations for use in livestock; veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; animal production efficiency enhancing veterinary preparations for increasing milk production and improving feed efficiency; intramammary veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions and diseases; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for shortening the dry-off period in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in livestock.

15.

MILAC

      
Numéro d'application 1541371
Statut Enregistrée
Date de dépôt 2020-05-21
Date d'enregistrement 2020-05-21
Propriétaire Mileutis Ltd. (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

Veterinary products, namely, preparations for use in livestock; veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; intramammary veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions and diseases; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms related to infections in livestock during the lactation period.

16.

IMILAC

      
Numéro de série 79301189
Statut Enregistrée
Date de dépôt 2020-05-21
Date d'enregistrement 2021-07-27
Propriétaire Mileutis Ltd. (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

Veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; animal production efficiency enhancing veterinary preparations for increasing milk production and improving feed efficiency; intramammary veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions and diseases; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for shortening the dry-off period in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in livestock

17.

MILAC

      
Numéro de série 79289809
Statut Enregistrée
Date de dépôt 2020-05-21
Date d'enregistrement 2021-03-16
Propriétaire Mileutis Ltd. (Israël)
Classes de Nice  ? 05 - Produits pharmaceutiques, vétérinaires et hygièniques

Produits et services

Veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; intramammary veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions and diseases; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms related to infections in livestock during the lactation period

18.

Casein peptide for use in the treatment of uterine infections

      
Numéro d'application 14946186
Numéro de brevet 09861678
Statut Délivré - en vigueur
Date de dépôt 2015-11-19
Date de la première publication 2016-11-10
Date d'octroi 2018-01-09
Propriétaire Mileutis Ltd. (Israël)
Inventeur(s) Iscovich, Jose Mario

Abrégé

The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of such infections by administering to a female mammalian animal at least one casein peptide, to the use of casein peptide for the preparation of a pharmaceutical composition for treatment of uterine infection and to a kit for said treatment. The casein peptide is preferably a casein hydrolysate, e.g. obtained by trypsin hydrolysis of casein protein. The female mammalian animal is, in accordance with some embodiments, a lactating animal, the infection being a post-partum infection.

Classes IPC  ?

  • A01N 37/18 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant le groupe —CO—N, p. ex. amides ou imides d'acide carboxyliqueLeurs thio-analogues
  • A61K 38/00 - Préparations médicinales contenant des peptides
  • A61P 31/04 - Agents antibactériens
  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
  • A61K 35/20 - LaitPetit-laitColostrum

19.

Peptides for management of lactation

      
Numéro d'application 14384395
Numéro de brevet 09487557
Statut Délivré - en vigueur
Date de dépôt 2013-03-08
Date de la première publication 2015-04-02
Date d'octroi 2016-11-08
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abrégé

The present invention provides novel short peptides that are highly effective in inducing involution in a mammary gland of a lactating mammal and cessation of milk production by the gland. The invention further provides pharmaceutical composition comprising the peptides and methods of use thereof including for treating microbial infection in a mammary gland.

Classes IPC  ?

  • C07K 1/00 - Procédés généraux de préparation de peptides
  • C07K 5/00 - Peptides ayant jusqu'à quatre amino-acides dans une séquence entièrement déterminéeLeurs dérivés
  • C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
  • A61K 38/07 - Tétrapeptides
  • A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
  • C07K 5/11 - Tétrapeptides la chaîne latérale du premier amino-acide contenant plus de groupes amino que de groupes carboxyle, ou leurs dérivés, p. ex. Lys, Arg
  • C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
  • A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains

20.

PEPTIDES FOR MANAGEMENT OF LACTATION

      
Numéro d'application IL2013050214
Numéro de publication 2013/140388
Statut Délivré - en vigueur
Date de dépôt 2013-03-08
Date de publication 2013-09-26
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abrégé

The present invention provides novel short peptides that are highly effective in inducing involution in a mammary gland of a lactating mammal and cessation of milk production by the gland. The invention further provides pharmaceutical composition comprising the peptides and methods of use thereof including for treating microbial infection in a mammary gland.

Classes IPC  ?

  • C07K 5/10 - Tétrapeptides
  • C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
  • C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
  • A61K 38/07 - Tétrapeptides
  • A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains

21.

Casein peptide for use in the treatment of uterine infections

      
Numéro d'application 13641959
Numéro de brevet 09220751
Statut Délivré - en vigueur
Date de dépôt 2011-04-17
Date de la première publication 2013-05-02
Date d'octroi 2015-12-29
Propriétaire Mileutis Ltd. (Israël)
Inventeur(s) Iscovich, Jose Mario

Abrégé

The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of such infections by administering to a female mammalian animal at least one casein peptide, to the use of casein peptide for the preparation of a pharmaceutical composition for treatment of uterine infection and to a kit for said treatment. The casein peptide is preferably a casein hydrolysate, e.g. obtained by trypsin hydrolysis of casein protein. The female mammalian animal is, in accordance with some embodiments, a lactating animal, the infection being a post-partum infection.

Classes IPC  ?

  • A01N 37/18 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant le groupe —CO—N, p. ex. amides ou imides d'acide carboxyliqueLeurs thio-analogues
  • A61K 38/00 - Préparations médicinales contenant des peptides
  • A61P 31/04 - Agents antibactériens
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés

22.

CASEIN PEPTIDE FOR USE IN THE TREATMENT OF UTERINE INFECTIONS

      
Numéro d'application IL2011000325
Numéro de publication 2011/132191
Statut Délivré - en vigueur
Date de dépôt 2011-04-17
Date de publication 2011-10-27
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s) Iscovich, Jose Mario

Abrégé

The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of such infections by administering to a female mammalian animal at least one casein peptide, to the use of casein peptide for the preparation of a pharmaceutical composition for treatment of uterine infection and to a kit for said treatment. The casein peptide is preferably a casein hydrolysate, e.g. obtained by trypsin hydrolysis of casein protein. The female mammalian animal is, in accordance with some embodiments, a lactating animal, the infection being a post-partum infection.

Classes IPC  ?

  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes

23.

Pharmaceutical compositions comprising casein derived peptides and methods of use thereof

      
Numéro d'application 13107331
Numéro de brevet 08338363
Statut Délivré - en vigueur
Date de dépôt 2011-05-13
Date de la première publication 2011-09-01
Date d'octroi 2012-12-25
Propriétaire
  • Mileutis Ltd. (Israël)
  • State of Israel, Ministry of Agriculture & Rural Development, Agriculture Research Organization (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Silanikove, Nissim
  • Iscovich, Javier

Abrégé

The present invention relates to peptides derived from casein and their use in the management of lactating animals, particularly to methods for decreasing the length of the dry period of a lactating livestock animal, for increasing its milk yield and milk hygiene after parturition and for improving the livestock welfare. The present invention further relates to pharmaceutical compositions comprising peptides derived from casein in the form of a sterile solution, which compositions are clear and substantially devoid of micelles.

Classes IPC  ?

  • A61K 38/00 - Préparations médicinales contenant des peptides
  • A61P 3/02 - Nutriments, p. ex. vitamines, minéraux
  • C07K 2/00 - Peptides à nombre indéterminé d'amino-acidesLeurs dérivés

24.

Pharmaceutical compositions comprising casein derived peptides and methods of use thereof

      
Numéro d'application 11913239
Numéro de brevet 07968513
Statut Délivré - en vigueur
Date de dépôt 2006-05-02
Date de la première publication 2009-03-12
Date d'octroi 2011-06-28
Propriétaire
  • Mileutis Ltd. (Israël)
  • State of Israel (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Silanikove, Nissim
  • Iscovich, Javier

Abrégé

The present invention relates to peptides derived from casein and their use in the management of lactating animals, particularly to methods for decreasing the length of the dry period of a lactating livestock animal, for increasing its milk yield and milk hygiene after parturition and for improving the livestock welfare. The present invention further relates to pharmaceutical compositions comprising peptides derived from casein in the form of a sterile solution, which compositions are clear and substantially devoid of micelles.

Classes IPC  ?

  • A61K 38/00 - Préparations médicinales contenant des peptides
  • A61P 3/02 - Nutriments, p. ex. vitamines, minéraux
  • C07K 2/00 - Peptides à nombre indéterminé d'amino-acidesLeurs dérivés

25.

LIVESTOCK MANAGEMENT FOR IMPROVED REPRODUCTIVE EFFICIENCY

      
Numéro d'application IL2007000469
Numéro de publication 2007/116410
Statut Délivré - en vigueur
Date de dépôt 2007-04-11
Date de publication 2007-10-18
Propriétaire
  • MILEUTIS LTD. (Israël)
  • STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (Israël)
Inventeur(s) Iscovich, Jose Mario

Abrégé

The present invention relates to methods for controlling the reproductive cycles and weaning in livestock, particularly to the use of casein-derived peptides for estrus induction and reduction of anestrus intervals, enabling early weaning without negatively affecting the livestock welfare. The present invention further relates to estrus synchronization in a livestock herd and to livestock management programs.

Classes IPC  ?

  • A23J 1/20 - Préparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir du lait, p. ex. caséinePréparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir du petit-lait
  • A23J 3/10 - Caséine
  • A23J 1/22 - Séchage de la caséine
  • A61K 38/00 - Préparations médicinales contenant des peptides

26.

PHARMACEUTICAL COMPOSITIONS COMPRISING CASEIN DERIVED PEPTIDES AND METHODS OF USE THEREOF

      
Numéro de document 02607155
Statut Délivré - en vigueur
Date de dépôt 2006-05-02
Date d'octroi 2016-09-13
Propriétaire
  • MILEUTIS LTD. (Israël)
  • STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Silanikove, Nissim
  • Iscovich, Javier

Abrégé


The present invention relates to peptides derived from casein and their use in
the management of lactating animals, particularly to methods for decreasing
the length of the dry period of a lactating livestock animal, for increasing
its milk yield and milk hygiene after parturition and for improving the
livestock welfare. The present invention further relates to pharmaceutical
compositions comprising peptides derived from casein in the form of a sterile
solution, which compositions are clear and substantially devoid of micelles.

Classes IPC  ?

  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains

27.

CASEIN PEPTIDE FOR USE IN THE TREATMENT OF UTERINE INFECTIONS

      
Numéro de document 02797658
Statut Délivré - en vigueur
Date de dépôt 2011-04-17
Date d'octroi 2021-06-08
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s) Iscovich, Jose Mario

Abrégé

The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of such infections by administering to a female mammalian animal at least one casein peptide, to the use of casein peptide for the preparation of a pharmaceutical composition for treatment of uterine infection and to a kit for said treatment. The casein peptide is preferably a casein hydrolysate, e.g. obtained by trypsin hydrolysis of casein protein. The female mammalian animal is, in accordance with some embodiments, a lactating animal, the infection being a post-partum infection.

Classes IPC  ?

  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes

28.

PEPTIDES FOR MANAGEMENT OF LACTATION

      
Numéro de document 02867557
Statut Délivré - en vigueur
Date de dépôt 2013-03-08
Date d'octroi 2020-03-10
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abrégé

The present invention provides novel short peptides that are highly effective in inducing involution in a mammary gland of a lactating mammal and cessation of milk production by the gland. The invention further provides pharmaceutical composition comprising the peptides and methods of use thereof including for treating microbial infection in a mammary gland.

Classes IPC  ?

  • A61K 38/07 - Tétrapeptides
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • C07K 5/10 - Tétrapeptides
  • C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
  • C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères

29.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS

      
Numéro de document 03273997
Statut En instance
Date de dépôt 2023-11-15
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Classes IPC  ?

  • A61K 35/20 - LaitPetit-laitColostrum
  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • A61K 38/38 - Albumines
  • A61K 38/40 - Transferrines, p. ex. lactoferrines, ovotransferrines
  • A61P 15/14 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs pour les troubles de la lactation, p. ex. galactorrhée

30.

ENHANCED MILK QUALITY

      
Numéro de document 03292174
Statut En instance
Date de dépôt 2024-05-16
Propriétaire MILEUTIS LTD. (Israël)
Inventeur(s)
  • Iscovich, Jose Mario
  • Iscovich, Javier

Classes IPC  ?

  • A23C 9/00 - Préparations à base de laitLait en poudre ou préparations à base de lait en poudre
  • A23C 9/12 - Préparations à base de lait fermentéTraitements utilisant des micro-organismes ou des enzymes
  • A23C 9/142 - Préparations à base de laitLait en poudre ou préparations à base de lait en poudre dans lesquelles la composition chimique du lait est modifiée par des traitements non chimiques par dialyse, osmose inverse ou ultrafiltration
  • A23C 9/20 - Produits diététiques à base de lait non couverts par les groupes
  • A23C 19/05 - Traitement du lait avant le caillageSéparation du petit-lait du lait caillé
  • A23J 1/20 - Préparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir du lait, p. ex. caséinePréparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir du petit-lait
  • A23J 3/10 - Caséine
  • A23K 10/10 - Produits alimentaires pour animaux obtenus par des procédés microbiologiques ou biochimiques
  • A23K 10/20 - Produits alimentaires pour animaux à base de matières d’origine animale
  • A23K 20/147 - Dérivés polymériques, p. ex. peptides ou protéines
  • A23K 50/10 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les ruminants
  • A23L 33/00 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement
  • A23L 33/19 - Protéines du lait
  • A61K 38/01 - Protéines hydrolyséesLeurs dérivés
  • A61K 38/07 - Tétrapeptides
  • A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
  • A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
  • C07K 5/103 - Tétrapeptides la chaîne latérale du premier amino-acide étant acyclique, p. ex. Gly, Ala
  • C07K 5/11 - Tétrapeptides la chaîne latérale du premier amino-acide contenant plus de groupes amino que de groupes carboxyle, ou leurs dérivés, p. ex. Lys, Arg
  • C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères