To enable highly efficient production of an olefin with a low environmental impact. The production includes a thermal cracking step of thermal cracking plastic to obtain a thermally cracked gas (G1) and a catalytic cracking step of cracking the thermally cracked gas (G1) in the presence of a catalyst to obtain a catalytically cracked gas (G2). When a ratio of an olefin to paraffin in the thermally cracked gas (G1) is indicated as R1 and a ratio of an olefin to paraffin in the catalytically cracked gas (G2) is indicated as R2, the following formula is satisfied: R2/R1 ≥1.
Provided are: a catalyst which has high hydrogenation activity even under a low pressure condition, for which production is relatively easy and low in cost, and which can be used in a hydrogen addition reaction; and a production method for the same. A catalyst according to the present invention includes a metal having activity in a hydrogenation addition reaction, a carrier carrying the metal, and boron added to the metal. The molar ratio of the boron relative to the metal is preferably 0.5-2.0. Furthermore, a production method for a catalyst according to the present invention includes: a step for preparing a raw material catalyst in which a metal is carried on a carrier; a step for adding boron to the raw material catalyst; and a step for reducing the raw material catalyst to which the boron was added.
C07C 5/10 - Préparation d'hydrocarbures à partir d'hydrocarbures contenant le même nombre d'atomes de carbone par hydrogénation de cycles aromatiques à six chaînons
C07C 13/18 - Hydrocarbures monocycliques ou leurs dérivés hydrocarbonés acycliques à cycle hexagonal à cycle du cyclohexane
3.
METHOD FOR ASSESSING AGGREGATION INHIBITING ACTIVITY OR AGGREGATION PROMOTING ACTIVITY ON AGGREGATED PROTEIN BY USING ORGANOID, AND METHOD FOR PRODUCING ORGANOID
The purpose of the present invention is to provide: a method for screening an aggregation inhibition activator or aggregation promotion activator for an aggregated protein; a method for producing an organoid; and an organoid produced by the method. Specifically, the present invention pertains to: a method for assessing the aggregation inhibiting activity or aggregation promoting activity of a test substance on an aggregated protein, the method comprising allowing an aggregated protein labeled in an aqueous solution, a test substance, and an organoid to coexist and quantifying, using the label as an indicator, aggregated and/or deposited aggregated proteins on the surface of the organoid and/or inside the organoid; and a method for producing an organoid, the method comprising culturing cells to form spheroids, embedding the obtained spheroids in a gel, and culturing the embedded spheroids in the gel.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
The objective of the present invention is to provide a method for visualizing an aggregate of aggregating proteins in an environment similar to in vivo conditions. More specifically, the present invention relates to a method for collecting an aggregating protein-containing solution by allowing an aggregating protein-containing solution to pass through a filtration filter through which a solution for accelerating and visualizing protein aggregation has passed; a method for visualizing an aggregate of aggregating proteins comprising visualizing an aggregate of aggregating proteins in the aggregating protein-containing solution collected by the collecting method; and a method of forming an aggregate of labeled aggregating proteins of interest in a medium or culture supernatant from which an aggregation inhibitor of 40 kDa or higher has been removed, so as to visualize aggregation.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
C07K 1/34 - ExtractionSéparationPurification par filtration, ultrafiltration ou osmose inverse
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
The present invention addresses the problem of developing and providing a novel aggregation inhibitor composed of a plant-derived extract and having an aggregation inhibiting effect on aggregation-prone proteins. Provided is an aggregation inhibitor composed of an extract of a plant selected from the group consisting of plants belonging to Asteraceae, Rosaceae, Saxifragaceae, Apiaceae, Liliaceae, Campanulaceae, Ericaceae, Lycopus, Geranium, Plantago, Hypericum, Stellaria, Chelidonium, Pachysandra, and Matteuccia.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
The present invention achieves olefin production with a low environmental burden and high efficiency. The present invention includes: a thermal cracking step for thermally decomposing a plastic to obtain a thermally cracked gas (G1); and a catalytic cracking step for decomposing the thermally cracked gas (G1) in the presence of a catalyst to obtain a catalytically cracked gas (G2). When the ratio of olefin relative to paraffin in the thermally cracked gas (G1) is indicated by R1 and the ratio of olefin relative to paraffin in the catalytically cracked gas (G2) is indicated by R2, R2/R1 is equal to or greater than 1.
C08J 11/12 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation uniquement par traitement à la chaleur sèche
C10G 1/10 - Production de mélanges liquides d'hydrocarbures à partir de schiste bitumineux, de sable pétrolifère ou de matières carbonées solides non fusibles ou similaires, p. ex. bois, charbon à partir de caoutchouc ou de déchets de caoutchouc
7.
AGGREGATING PROTEIN MEASURING METHOD, AGGREGATION VISUALIZING METHOD, AND KIT FOR USE IN SAID METHODS
The objective of the present invention is to provide a method for visualizing an aggregate of an aggregating protein in an environment similar to biological conditions, and more specifically relates to: a method for recovering an aggregating protein-containing solution by passing the aggregating protein-containing solution through a filtration filter through which a protein aggregation promoting and visualizing liquid has been passed; a method for visualizing an aggregate of the aggregating protein, including visualizing the aggregate of the aggregating protein in the aggregating protein-containing solution recovered by said recovery method; and a method for visualizing aggregation by causing an aggregate of a marked target aggregating protein to form in a culture medium or a culture supernatant from which an aggregation inhibiting substance of at least 40 kDa has been removed.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
C07K 1/30 - ExtractionSéparationPurification par précipitation
C07K 1/34 - ExtractionSéparationPurification par filtration, ultrafiltration ou osmose inverse
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
Provided is a method for producing olefins, in which the yield of olefins having 2-3 carbon atoms is excellent. This method for producing olefins includes a step (1) and a step (2). Step (1): a step for heating a polyolefin-based plastic so as to obtain a decomposition product (a thermal decomposition step). Step (2): a step for bringing the decomposition product obtained in step (1) into contact with an MFI type zeolite containing 0.10-0.30 mass% of sodium atoms so as to obtain an olefin-containing catalytically cracked product (a catalytic cracking step).
This production method for a molded body includes: a molding step for heating and applying pressure to a composition that includes a structural protein and has a water content of at least 6% to obtain a molded body; and a rolling step for rolling the molded body obtained in the molding step at a rolling reduction of at least 60%.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
B29C 43/00 - Moulage par pressage, c.-à-d. en appliquant une pression externe pour faire couler la matière à moulerAppareils à cet effet
C12N 15/12 - Gènes codant pour des protéines animales
10.
METHOD FOR PRODUCING MOLDED PRODUCT AND MOLDED PRODUCT
Provided is a method for producing a molded product comprising: a step 1 for molding a composition containing a structural protein; and a step 2 for compressing and stretching the molded composition obtained in the step 1.
B29C 55/18 - Façonnage par étirage, p. ex. étirage à travers une matriceAppareils à cet effet de plaques ou de feuilles par serrage entre des surfaces, p. ex. des rouleaux
B29C 43/02 - Moulage par pressage, c.-à-d. en appliquant une pression externe pour faire couler la matière à moulerAppareils à cet effet pour la fabrication d'objets de longueur définie, c.-à-d. d'objets séparés
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A disinfectant having higher safety compared with a case where only hydroxide calcium is used. A disinfectant containing slags is sprayed onto the ground in and around a barn, on the outer edge of a farm or the like (S1). The sprayed granules of the disinfectant are trampled down by a human body or a vehicle to crush or grind the granules (S2). A portion of the crushed or ground product of the disinfectant, which is adhered to the human body, the vehicle or the like that crushed or ground the granules, is transported together with the human body, the vehicle or the like (S3). The deterioration of the disinfection efficacy of the disinfectant can be detected by checking whether or not the disinfectant turns purple with naked eyes (S4). When the deterioration of the disinfection efficacy of the disinfectant is detected, the disinfectant is resprayed (S5).
Provided is a novel aromatic polyester which has low melt viscosity and good fluidity even if the molecular weight thereof is high. Specifically provided is an aromatic polyester containing a polyvalent phenolic residue and a residue of an aromatic polyvalent carboxylic acid, acid halide thereof or acid anhydride thereof, which is characterized in that the residue of an aromatic polyvalent carboxylic acid, acid halide thereof or acid anhydride thereof is composed of a residue of an aromatic dicarboxylic acid, acid halide thereof or acid anhydride thereof and a residue of an aromatic tricarboxylic acid, acid halide thereof or acid anhydride thereof and that (the mole number of the residue of an aromatic tricarboxylic acid, acid halide thereof or acid anhydride thereof)/[(the mole number of the residue of an aromatic dicarboxylic acid, acid halide thereof or acid anhydride thereof) + (the mole number of the residue of an aromatic tricarboxylic acid, acid halide thereof or acid anhydride thereof)] = 0.001-0.090.
Provided is an aromatic polyester which is rarely discolored even after high-temperature molding and retains remarkably high transparency and which exhibits high flowability. An aromatic polyester which comprises both residues of a polyhydric phenol and residues of an aromatic polycarboxylic acid, or an acid halide or acid anhydride thereof, characterized by bearing structures represented by the general formula: -C(O)-R at the terminals with the terminal blocking ratio being 90% or more, and by having a weight-average molecular weight (Mw) of 3,000 to 1,000,000.
An ultrasonic actuator for rotating a rotor, small-sized and capable of being easily voltage-controlled. The ultrasonic actuator has a plate-like vibrator and piezoelectric elements. The plate-like vibrator is at one end in contact with the rotor, has a bent corner in the middle, and is extended until the other end is fixed to position. The piezoelectric elements are in contact with a portion between the one end and the corner, vibrates by receiving an AC voltage between either of two electrodes on both sides of the vibrator or a plate-like vibrator that doubles as the either of the two electrodes and the other electrode, and transmits the vibration to the vibrator.