05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Pharmaceutical products, medical and veterinary preparations; Fillings for teeth; Materials for making dental impressions; Chemical-pharmaceutical products; Health products, namely, pharmaceutical products, medical and veterinary preparations; Radiological contrast substances for medical use; Chemical reagents for medical use; Biological reagents for medical use; Chemical preparations for medical or pharmaceutical use; Diagnostic preparations for medical purposes; Medicines for human medicine; Products for medical use, namely for the diagnosis and treatment of tumors Medical apparatus and instruments for use in surgery; Medical instruments, namely, orthopedic apparatus and instruments; Prosthetics; Artificial implant prostheses; Radiotherapy apparatus; Surgical apparatus and instruments for medical use; Apparatus for medical diagnosis; Surgical and medical devices and instruments Biological research; Radiobiology research; Research in nanoscience and nanotechnology, particularly applied to medicine; Scientific research; Computer software design; Computer design services; Scientific and technological services as well as research and design services, particularly in the field of nanomedicine namely nanotechnology applied to medicine; Technical research; Information technology consulting
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Products for medical use for the treatment of psychiatric diseases and disorders; Preparation for the diagnosis and treatment of brain diseases and disorders; Preparation for medical use for the treatment of Parkinson's disease, Alzheimer's disease, epilepsy and all types of neurological and neuropsychiatric disorders and diseases; Preparation for medical use for the treatment of symptoms of Parkinson's disease, symptoms of Alzheimer's disease, symptoms of epilepsy and symptoms linked to all types of neurological and neuropsychiatric disorders and diseases; Preparation for the diagnosis and treatment of neurological disorders and diseases using deep brain stimulation, transcranial electrical stimulation, transcranial direct current stimulation, transcranial magnetic stimulation, any form of electromagnetic stimulation including light, magnetic field, electric field, radio frequency or ultrasound stimulation; Nanoparticles for medical use; Chemical reagents for medical use; Chemical preparations for medical or pharmaceutical use; Diagnostic preparations for medical purposes; Medicines for human medicine; Pharmaceutical products Surgical and medical devices and instruments, in particular for the diagnosis and treatment of tumors; Surgical and medical apparatus and instruments, in particular for the diagnosis and treatment of cerebral diseases and disorders; Surgical and medical devices and instruments for deep brain stimulation, transcranial electrical stimulation, transcranial direct current stimulation, transcranial magnetic stimulation, any form of electromagnetic stimulation including light, magnetic field, electric field, radiofrequency or ultrasound stimulation; Apparatus for delivering therapeutic or diagnostic agents; Device for recording cerebral electrical activity including electrodes, electroencephalograph, microelectrode arrays Scientific and technological services as well as research and design services, particularly in the field of nanomedicine, namely, nanotechnology applied to medicine; Biological research; Design and development of new products for third parties; Chemical analysis; Research in the field of chemistry; Neuroscience research; Radiobiology research
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products, medical and veterinary preparations; Disinfectants for hygiene purposes; Medical plasters; Fillings for teeth; Materials for making dental impressions; Disinfectants; Fungicides; Herbicides; Antibiotics; Antiseptics; Health products, namely, pharmaceutical products, medical and veterinary preparations; Radiological contrast substances for medical use; Chemical reagents for medical use; Bacteriological preparations for medical use; Biological reagents for medical use; Chemical preparations for medical or pharmaceutical use; Diagnostic preparations for medical purposes; Products for medical use, namely for the diagnosis and treatment of tumor Medical apparatus and instruments for use in surgery; Dental appliances and instruments; Medical instruments, namely, orthopedic apparatus and instruments; Prosthetics; Artificial implant prostheses; Therapeutic and assistance devices for disabled people; Radiotherapy apparatus; Apparatus for medical diagnosis; Medical X-ray apparatus; Surgical apparatus and instruments for medical use
4.
INORGANIC NANOPARTICLES COMPOSITIONS IN COMBINATION WITH IONIZING RADIATIONS FOR TREATING CANCER
The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cancerous cells, tissues or organs. It more particularly relates to nanoparticles which can generate a surprisingly efficient therapeutic effect, when concentrated inside the tumor and exposed to ionizing radiations. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.
The invention concerns a novel and innovative composition for the treatment of neuropathic pain (NP). Specifically, the invention concerns nanoparticles and/or aggregates of nanoparticles, a composition comprising said nanoparticles and/or aggregates of nanoparticles, and their use in the treatment of NP.
The invention concerns a particle and a composition comprising particles and their use in oncology. Specifically, the particles are porous, high-Z and carbon-free particles having internal pores, of longest dimension of at least 0.5 nm, and are for use in altering or destroying target cells in a mammal when said cells are exposed to ionizing radiation.
The invention concerns a particle and a composition comprising particles and their use in oncology. Specifically, the particles are porous, high-Z and carbon-free particles having internal pores, of longest dimension of at least 0.5 nm, and are for use in altering or destroying target cells in a mammal when said cells are exposed to ionizing radiation.
The present invention also provides a porous, high-Z and carbon-free particle wherein at least part of the porous structure of the particle is occupied by at least one therapeutic agent which is preferably for use in oncology.
The invention relates to nanoparticles and/or aggregates of nanoparticles and a composition comprising nanoparticles and/or aggregates of nanoparticles and their use in oncology. Specifically, the nanoparticles and/or aggregates of nanoparticles are radiation enhancer agents to be activated by ionizing radiation, and are for use, in combination with at least one immunooncology (IO) agent, in the treatment of malignant tumors in human patients who have failed to respond to a previous immunotherapy and/or radiotherapy (RT) and who experience disease progression.
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61P 35/04 - Agents anticancéreux spécifiques pour le traitement des métastases
The present disclosure offers therapeutic solutions to cancer patients up to now considered as unable to undergo a standard-of-care treatment involving radiotherapy or at high risk to undergo a standard-of-care treatment involving radiotherapy. The disclosure relates to nanoparticles and/or aggregates of nanoparticles for use in the treatment of cancer in such a patient, wherein the nanoparticles and/or aggregates of nanoparticles preferably comprise more than 30% by weight of at least one chemical element having an atomic number (Z) between 20 and 83. The disclosed treatments involve a step of administering the nanoparticles and/or aggregates of nanoparticles to the patient, and a step of exposing the patient to a total dose of ionizing radiations that is equal to or less than 85% of the total dose delivered in the standard-of-care treatment. The present description also discloses new compositions comprising such nanoparticles and/or aggregates of nanoparticles as well as uses thereof.
ijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
The invention concerns a particle and a composition comprising particles and their use in oncology. Specifically, the particles are porous, high-Z and carbon-free particles having internal pores, of longest dimension of at least 0.5 nm, and are for use in altering or destroying target cancerous cells in a mammal when said cells are exposed to ionizing radiation. The present invention also provides a porous, high-Z and carbon-free particle wherein at least part of the porous structure of the particle is occupied by at least one therapeutic agent which is preferably for use in oncology.
The invention concerns a particle and a composition comprising particles and their use in oncology. Specifically, the particles are porous, high-Z and carbon-free particles having internal pores, of longest dimension of at least 0.5 nm, and are for use in altering or destroying target cancerous cells in a mammal when said cells are exposed to ionizing radiation. The present invention also provides a porous, high-Z and carbon-free particle wherein at least part of the porous structure of the particle is occupied by at least one therapeutic agent which is preferably for use in oncology.
The invention relates to nanoparticles and/or aggregates of nanoparticles and a composition comprising nanoparticles and/or aggregates of nanoparticles and their use in oncology. Specifically, the nanoparticles and/or aggregates of nanoparticles are radiation enhancer agents to be activated by ionizing radiation, and are for use, in combination with at least one immuno-oncology (IO) agent, in the treatment of malignant tumors in human patients who have failed to respond to a previous immunotherapy and/or radiotherapy (RT) and who experience disease progression.
The invention relates to nanoparticles and/or aggregates of nanoparticles and a composition comprising nanoparticles and/or aggregates of nanoparticles and their use in oncology. Specifically, the nanoparticles and/or aggregates of nanoparticles are radiation enhancer agents to be activated by ionizing radiation, and are for use, in combination with at least one immuno-oncology (IO) agent, in the treatment of malignant tumors in human patients who have failed to respond to a previous immunotherapy and/or radiotherapy (RT) and who experience disease progression.
The present invention relates to the field of human health and advantageously offers therapeutic solutions to cancer patients up to now considered by multidisciplinary (oncology) teams (considering guidelines standards) as unable to undergo a standard-of-care treatment involving radiotherapy or at high risk to undergo a standard-of-care treatment involving radiotherapy. The invention more particularly relates to nanoparticles and/or aggregates of nanoparticles for use in the treatment of cancer in such a patient, wherein the nanoparticles and/or aggregates of nanoparticles preferably comprise more than 30% by weight of at least one chemical element having an atomic number (Z) between 20 and 83. The treatment of cancer typically involves a step of administering the nanoparticles and/or aggregates of nanoparticles to the patient, and a step of exposing the patient who has been administered with the nanoparticles and/or aggregates of nanoparticles to a total dose of ionizing radiations that is equal to or less than 85 of the total dose delivered in the standard-of-care treatment. The present description in addition discloses new compositions comprising such nanoparticles and/or aggregates of nanoparticles as well as uses thereof.
The present invention relates to the field of human health and more particularly concerns nanoparticles for use as a therapeutic vaccine in the context of radiotherapy in a subject suffering of a cancer, in particular of a metastatic cancer or of a liquid cancer.
The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cancerous cells, tissues or organs. It more particularly relates to nanoparticles which can generate a surprisingly efficient therapeutic effect, when concentrated inside the tumor and exposed to ionizing radiations. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Chemical products for medical use particularly for tumor
diagnosis and treatment; chemical products for medical use
particularly for tumor diagnosis and treatment by radiation
therapy; radioactive products for medical use particularly
for tumor diagnosis and treatment by radiation therapy;
health products namely pharmaceutical products; radiological
contrast substances for medical use; chemical reagents for
medical use; bacteriological preparations for medical use;
biological preparations for medical use; enzymes for
medical use; enzyme preparations for medical use; chemical
preparations for medical or pharmaceutical use; diagnostic
chemicals for medical use; drugs for medical use; medicines
for human medicine; tonics [medicines]; antibiotics;
antiseptics; chemico-pharmaceutical products;
pharmaceutical products; dietetic substances for medical
use; remedies for human medicine. Surgical and medical apparatus and instruments particularly
for tumor diagnosis and treatment by radiation therapy;
radiotherapy apparatus; testing apparatus for medical use;
diagnostic apparatus for medical use; radiology screens for
medical use; X-ray photographs for medical use;
radiological apparatus for medical use; X-ray tubes for
medical use; filters and lamps for ultraviolet rays for
medical use; apparatus and installations for the production
of X-rays for medical use; protection devices against
X-rays, for medical use; X-ray apparatus for medical use;
protection devices against X-rays for medical use;
receptacles for applying medicines; special furniture for
medical use; radium tubes for medical use.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products, namely, preparations for medical use particularly for tumor diagnosis and treatment; pharmaceutical products, namely, preparations for medical use, especially for the diagnosis and treatment of tumors using radiotherapy; radioactive products, namely, substances for medical use, especially for the diagnosis and treatment of tumors using radiotherapy; health products, namely, pharmaceutical products, for the treatment of tumors; radiological contrast substances for medical use; chemical reagents for medical use; chemical preparations for medical or pharmaceutical use, namely, for the treatment of tumors; diagnostic products for medical use, namely, medicines for the treatment of tumors; drugs for medical use, namely, pharmaceutical products for use in the treatment of cancer; medicines for human medicine, namely, pharmaceutical products for the treatment of tumors; chemicopharmaceutical products for use in treating oncological diseases and disorders; pharmaceutical products for use in treating oncological diseases and disorders Surgical and medical apparatus and instruments, namely, radiotherapy apparatus especially for the diagnosis and treatment of tumors using radiotherapy; radiotherapy apparatus; testing apparatus for medical use, namely, for testing tumor characteristics; diagnosis apparatus for medical use, namely, for testing tumor characteristics; radiological apparatus for medical use; apparatus and installations for the production of X-Rays for medical use
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Products for medical use for the diagnosis and treatment of
tumors; products for medical use for the diagnosis and
treatment of tumors using radiation therapy; products for
medical use for the diagnosis and treatment of tumors using
radiotherapy and immunotherapy; radiation potentiator
products for the diagnosis and treatment of tumors using
radiation therapy; healthcare products, namely,
pharmaceutical products for the treatment of tumors using
radiotherapy and for the treatment of tumors using
radiotherapy and immunotherapy; radiological contrast
substances for medical use; nanoparticles for medical use;
biological preparations incorporating nanoparticles of metal
and/or metal oxides for medical use; chemical preparations
incorporating nanoparticles of metal and/or metal oxides for
medical or pharmaceutical use; diagnostic products for
medical use; medicines based on nanoparticles of metal
and/or metal oxides for human medicine;
chemical-pharmaceutical products based on nanoparticles of
metal and/or metal oxides; pharmaceutical products based on
nanoparticles of metal and/or metal oxides. Medical devices for the diagnosis and treatment of tumors
using radiation therapy; Medical devices for the diagnosis
and treatment of tumors using radiotherapy and
immunotherapy; devices for radiotherapy; diagnostic devices
for medical use.
23.
Nanoparticles for use for treating a neuronal disorder
ijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof without exposure thereof to an electric field, and preferably without exposure thereof to any other external activation source.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
ijk equal to or below (100). It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof without exposure thereof to an electric field, and preferably without exposure thereof to any other external activation source such as a light source, a magnetic field, or an ultrasound source.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Products for medical use particularly for tumor diagnosis
and treatment; products for medical use, especially for the
diagnosis and treatment of tumors using radiotherapy;
radioactive products for medical use, especially for the
diagnosis and treatment of tumors using radiotherapy;
health products namely pharmaceutical products;
radiological contrast substances for medical use; chemical
reagents for medical use; bacteriological preparations for
medical use; biological preparations for medical use;
enzymes for medical use; enzyme preparations for medical
use; chemical preparations for medical or pharmaceutical
use; diagnostic products for medical use; drugs for
medical use; medicines for human medicine; tonics
[medicines]; antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical products;
dietetic substances for medical use; remedies for human
medicine. Surgical and medical apparatus and instruments, especially
for the diagnosis and treatment of tumors using
radiotherapy; radiotherapy apparatus; testing apparatus
for medical use; diagnostic apparatus for medical use;
radiology screens for medical use; X-ray photographs for
medical use; radiological apparatus for medical use;
Roentgen-rays tubes for medical purposes; filters and lamps
for ultraviolet rays for medical use; apparatus and
installations for the production of X-rays for medical use;
protection devices against X-rays, for medical use;
roentgen apparatus for medical purposes; roentgen radiation
protection devices for medical use; receptacles for applying
medicines; special furniture for medical use; radium tubes
for medical use. Scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine);
biological research; research in bacteriology; evaluations,
estimates and research in scientific and technological
fields provided by engineers, researchers; design and
development of new products (for third parties); technical
project studies; industrial analysis and research services;
chemical analysis; chemical research; chemistry services;
surveying [engineering work]; research and development of
new products for third parties; technical research
services; radiobiology research; research in nanoscience
and nanotechnology, especially applied to medicine. Healthcare especially in the field of nanomedicine; medical
services especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Products for medical use particularly for tumor diagnosis
and treatment; products for medical use, especially for the
diagnosis and treatment of tumors using radiotherapy;
radioactive products for medical use, especially for the
diagnosis and treatment of tumors using radiotherapy;
health products namely pharmaceutical products;
radiological contrast substances for medical use; chemical
reagents for medical use; bacteriological preparations for
medical use; biological preparations for medical use;
enzymes for medical use; enzyme preparations for medical
use; chemical preparations for medical or pharmaceutical
use; diagnostic products for medical use; drugs for
medical use; medicines for human medicine; tonics
[medicines]; antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical products;
dietetic substances for medical use; remedies for human
medicine; products for medical use particularly for tumor
diagnosis and treatment; products for medical use,
especially for the diagnosis and treatment of tumors using
radiotherapy; radioactive products for medical use,
especially for the diagnosis and treatment of tumors using
radiotherapy; health products namely pharmaceutical
products; radiological contrast substances for medical use;
chemical reagents for medical use; bacteriological
preparations for medical use; biological preparations for
medical use; enzymes for medical use; enzyme preparations
for medical use; chemical preparations for medical or
pharmaceutical use; diagnostic products for medical use;
drugs for medical use; medicines for human medicine; tonics
[medicines]; antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical products;
dietetic substances for medical use; remedies for human
medicine. Surgical and medical apparatus and instruments, especially
for the diagnosis and treatment of tumors using
radiotherapy; radiotherapy apparatus; testing apparatus
for medical use; diagnostic apparatus for medical use;
radiology screens for medical use; X-ray photographs for
medical use; radiological apparatus for medical use;
Roentgen-rays tubes for medical purposes; filters and lamps
for ultraviolet rays for medical use; apparatus and
installations for the production of X-rays for medical use;
protection devices against X-rays, for medical use;
roentgen apparatus for medical purposes; roentgen radiation
protection devices for medical use; receptacles for applying
medicines; special furniture for medical use; radium tubes
for medical use; surgical and medical apparatus and
instruments, especially for the diagnosis and treatment of
tumors using radiotherapy; radiotherapy apparatus; testing
apparatus for medical use; diagnostic apparatus for medical
use; radiology screens for medical use; X-ray photographs
for medical use; radiological apparatus for medical use;
Roentgen-rays tubes for medical purposes; filters and lamps
for ultraviolet rays for medical use; apparatus and
installations for the production of X-rays for medical use;
protection devices against X-rays, for medical use;
roentgen apparatus for medical purposes; roentgen radiation
protection devices for medical use; receptacles for applying
medicines; special furniture for medical use; radium tubes
for medical use. Scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine);
biological research; research in bacteriology; evaluations,
estimates and research in scientific and technological
fields provided by engineers, researchers; design and
development of new products (for third parties); technical
project studies; industrial analysis and research services;
chemical analysis; chemical research; chemistry services;
surveying [engineering work]; research and development of
new products for third parties; technical research;
radiobiology research; research in nanoscience and
nanotechnology, especially applied to medicine; scientific
and technological services as well as research and design
services particularly in the field of nanomedicine
(nanotechnology applied to medicine); biological research;
research in bacteriology; evaluations, estimates and
research in scientific and technological fields provided by
engineers, researchers; design and development of new
products (for third parties); technical project studies;
industrial analysis and research services; chemical
analysis; chemical research; chemistry services; surveying
[engineering work]; research and development of new
products for third parties; technical research;
radiobiology research; research in nanoscience and
nanotechnology, especially applied to medicine. Healthcare especially in the field of nanomedicine; medical
services especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy; healthcare
especially in the field of nanomedicine; medical services
especially in the field of nanomedicine; hospital services;
medical assistance; physiotherapy.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Products for medical use especially for metabolic pathways;
products for medical use especially for the diagnosis and
treatment of tumors; preparation for medical use especially
for modifying the bioavailability of therapeutic agents;
preparations for medical use especially for modifying liver
functions; preparation for medical use for modifying the
functions of the reticuloendothelial system; preparation
based on nanomaterials for the delivery of therapeutic
agents; nanoparticles for medical use; chemical reagents
for medical use; bacteriological preparations for medical
use; biological preparations for medical use; enzymes for
medical use; enzyme preparations for medical use; chemical
preparations for medical or pharmaceutical use; diagnostic
products for medical use; drugs for medical use; medicines
for human medicine; tonics (medicines); antibiotics;
antiseptics; chemico-pharmaceutical products;
pharmaceutical products; dietetic substances for medical
use; remedies for human medicine. Scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine);
biological research; research in bacteriology; evaluations,
estimates and research in scientific and technological
fields provided by engineers and researchers; design and
development of new products (for third parties); technical
project studies; industrial analysis and research services;
chemical analysis; chemical research; chemistry services;
surveying (engineering work); research and development of
new products for third parties; technical research;
radiobiology research; research in nanoscience and
nanotechnology, especially applied to medicine. Healthcare especially in the field of nanomedicine; medical
services especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical products, namely, preparations for medical use particularly for tumor diagnosis and treatment; pharmaceutical products, namely, preparations for medical use, especially for the diagnosis and treatment of tumors using radiotherapy; radioactive products, namely, substances for medical use, especially for the diagnosis and treatment of tumors using radiotherapy; health products, namely, pharmaceutical products, for the treatment of tumors; radiological contrast substances for medical use; chemical reagents for medical use; chemical preparations for medical or pharmaceutical use, namely, for the treatment of tumors; diagnostic products for medical use, namely, medicines for the treatment of tumors; drugs for medical use, namely, pharmaceutical products for use in the treatment of cancer; medicines for human medicine, namely, pharmaceutical products for the treatment of tumors; chemico-pharmaceutical products for use in treating oncological diseases and disorders; pharmaceutical products for use in treating oncological diseases and disorders Surgical and medical apparatus and instruments, namely radiotherapy apparatus especially for the diagnosis and treatment of tumors using radiotherapy; radiotherapy apparatus; testing apparatus for medical use, namely, for testing tumor characteristics; diagnostic apparatus for medical use, namely, for testing tumor characteristics; radiological apparatus for medical use; apparatus and installations for the production of X-Rays for medical use Scientific and technological services, namely, research and design services particularly in the field of nanomedicine which is nanotechnology applied to medicine; biological research; research in bacteriology; scientific research, namely, evaluations, estimates and research in scientific and technological fields provided by engineers, researchers; design and development of new products for third parties; technical project studies, namely, technical research in the field of nanomedicine; industrial analysis of manufacturing of nanomedicines and research services in the field of nanomedicine; chemical analysis; chemical research; chemistry services, namely, chemistry consultation; surveying Healthcare especially in the field of nanomedicine; medical services especially in the field of nanomedicine; hospital services; medical assistance; physiotherapy
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products, namely, preparations for medical use particularly for the diagnosis and treatment of tumors; pharmaceutical products, namely, preparations for medical use particularly for the diagnosis and treatment of tumors using radiotherapy; pharmaceutical products, namely, preparations for medical use particularly for the diagnosis and treatment of tumors using radiotherapy and immunotherapy; X-ray enhancing agents for medical use for the diagnosis and treatment of tumors using radiotherapy, namely, radioenhancers; X-ray contrast agents for medical use for the diagnosis and treatment of tumors using radiotherapy, namely, radioenhancers; health goods, namely, pharmaceutical preparations for the treatment of tumors using radiotherapy and for the treatment of tumors using radiotherapy and immunotherapy; radiological contrast substances for medical use; nanoparticles for medical use; biological preparations with metallic nanoparticles and/or metal oxides for medical use; chemical preparations with metallic nanoparticles and/or metal oxides for medical or pharmaceutical use; medicinal products, namely, radioenhancers based on metallic nanoparticles and/or metal oxides for medical use for human medicine; chemical pharmaceutical products with metallic nanoparticles and/or metal oxides for the diagnosis of cancer Injectable medical device containing inert metal for the diagnosis and treatment of tumors
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical products, namely, preparations for medical use particularly for tumor diagnosis and treatment; pharmaceutical products, namely, preparations for medical use, especially for the diagnosis and treatment of tumors using radiotherapy; radioactive products, namely, substances for medical use, especially for the diagnosis and treatment of tumors using radiotherapy; health products, namely, pharmaceutical products, for the treatment of tumors; radiological contrast substances for medical use; chemical reagents for medical use; chemical preparations for medical or pharmaceutical use, namely, for the treatment of tumors; diagnostic products for medical use, namely, medicines for the treatment of tumors; drugs for medical use, namely, pharmaceutical products for use in the treatment of cancer; medicines for human medicine, namely, pharmaceutical products for the treatment of tumors; chemico-pharmaceutical products for use in treating oncological diseases and disorders; pharmaceutical products for use in treating oncological diseases and disorders Surgical and medical apparatus and instruments, namely radiotherapy apparatus especially for the diagnosis and treatment of tumors using radiotherapy; radiotherapy apparatus; testing apparatus for medical use, namely, for testing tumor characteristics; diagnostic apparatus for medical use, namely, for testing tumor characteristics; radiological apparatus for medical use; apparatus and installations for the production of X-Rays for medical use Scientific and technological services, namely, research and design services particularly in the field of nanomedicine which is nanotechnology applied to medicine; biological research; research in bacteriology; scientific research, namely, evaluations, estimates and research in scientific and technological fields provided by engineers, researchers; design and development of new products for third parties; technical project studies, namely, technical research in the field of nanomedicine; industrial analysis of manufacturing of nanomedicines and research services in the field of nanomedicine; chemical analysis; chemical research; chemistry services, namely, chemistry consultation; surveying Healthcare especially in the field of nanomedicine; medical services especially in the field of nanomedicine; hospital services; medical assistance; physiotherapy
05 - Produits pharmaceutiques, vétérinaires et hygièniques
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Products for medical use especially for metabolic pathways to prevent and treat acid-base imbalance, metabolic brain diseases, disorders of calcium metabolism, DNA repair-deficiency disorders, glucose metabolism disorders, hyperlactatemia, iron metabolism disorders, lipid metabolism disorders, malabsorption syndromes, metabolic syndrome X, inborn error of metabolism, mitochondrial diseases, phosphorus metabolism disorders, porphyrias, proteostasis deficiencies, metabolic skin diseases, wasting syndrome and water-electrolyte imbalance; products for medical use especially for the diagnosis and treatment of tumors; preparations for medical use especially for modifying the bioavailability of therapeutic agents; preparations for medical use especially for modifying liver functions to prevent and treat alcohol-related liver disease, non-alcoholic fatty liver disease, hepatitis, haemochromatosis, primary biliary cirrhosis and liver cancer; preparations for medical use for modifying the functions of the reticuloendothelial system to decrease reticuloendothelial system ability to trap and metabolize therapeutic agents such as nanomedicines, monoclonal antibodies, antibody-drug conjugates, small molecules, and to prevent and treat Gaucher's disease, mastocytosis, and histiocytosis; preparations based on nanomaterials for the delivery of therapeutic agents combined with nucleic acid, small molecules, proteins and peptides; nanoparticles for medical use to prevent and treat central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, organ transplant rejection; chemical reagents for medical use; bacteriological preparations for medical use; biological preparations for medical use to prevent and treat central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, organ transplant rejection; enzymes for medical use; enzyme preparations for medical use; diagnostic products for medical use to prevent and treat central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, and organ transplant rejection; drugs for medical use to prevent and treat central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, and organ transplant rejection; medicines for human to prevent and treat central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, and organ transplant rejection; tonics for medical use to prevent and treat central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, and organ transplant rejection; antibiotics; antiseptics; chemico-pharmaceutical preparations for the treatment of central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, and organ transplant rejection; pharmaceutical preparations for the treatment of central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, and organ transplant rejection; dietetic substances preparations adapted for medical use; remedies for human medicine for the treatment of central nervous system diseases, cancer, metabolic diseases, infection, immunologic diseases, hematologic disease, rare diseases, and organ transplant rejection Scientific and technological services as well as, namely, research and design services particularly in the field of nanomedicine which is nanotechnology applied to medicine; biological research; research in bacteriology; conducting early evaluations in the field of new pharmaceuticals; design and development of new products for third parties; conducting clinical trials for others in the field of new pharmaceuticals; research services in the field of new pharmaceuticals; chemical analysis; chemical research; chemical engineering; chemical research and analysis services in the field of physico-chemical characterization and concept design; engineering work, namely, surveying; research and development of new products for third parties; technical research in the field of new pharmaceuticals; radiobiology research; research in nanoscience and nanotechnology, especially applied to medicine Healthcare especially in the field of nanomedicine; medical services especially in the field of nanomedicine; hospital services; medical assistance; physiotherapy
32.
Nanoparticles for use for enhancing brain performances or for treating stress
ijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
The present invention relates to a pharmaceutical composition comprising the combination of (i) a biocompatible nanoparticle and of (ii) a pharmaceutical compound of interest, to be administered to a subject in need of such a compound of interest, wherein the nanoparticle potentiates the compound of interest efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm, and its absolute surface charge value is of at least 10 mV (|10 mV|). The invention also relates to such a composition for use for administering the compound of interest to a subject in need thereof, wherein the nanoparticle and the compound of interest are to be administered to said subject between more than 5 minutes and about 72 hours from each other.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
34.
Pharmaceutical composition combining at least two distinct nanoparticles and a pharmaceutical compound, preparation and uses thereof
The present invention relates to a pharmaceutical composition comprising the combination of (i) at least two distinct biocompatible nanoparticles and (ii) at least one compound of interest, typically at least one pharmaceutical compound, to be administered to a subject in need of such at least one compound of interest, wherein the at least two distinct biocompatible nanoparticles potentiate the compound(s) of interest efficiency. The at least two biocompatible nanoparticles can be administered sequentially or simultaneously to the subject but are to be administered separately, typically with an interval of between more than about 5 minutes and about 72 hours, from the at least one compound of interest, preferably before the administration of the at least one compound of interest, to said subject. The longest dimension of the at least two biocompatible nanoparticles is typically between about 4 nm and about 500 nm. The absolute surface charge value of a first biocompatible nanoparticle is of at least |10 mV| and the absolute surface charge value of the second biocompatible nanoparticle, or of any additional biocompatible nanoparticle, has a difference of at least 10 mV with the absolute surface charge value of the first biocompatible nanoparticle.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
35.
Nanoparticles for use for treating a neuronal disorder
ijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
The present invention relates to the medical field, in particular to the modulation of electrical polarization of neurons. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use for modulating electrical polarization of neurons in a subject, for example for use in prevention or treatment of a neuronal disease in a subject, typically by modulating electrical polarization of neurons in the subject, wherein i) when the nanoparticle or nanoparticles' aggregate is exposed to a light source, the nanoparticle's or nanoparticles' aggregate's material is selected from a material enabling opto-electric transduction, opto-thermal transduction or opto-optical transduction, ii) when the nanoparticle or nanoparticles' aggregate is exposed to a magnetic field, the nanoparticle's or nanoparticles' aggregate's material is selected from a material enabling magneto-electric transduction or magneto-thermal transduction, iii) when the nanoparticle or nanoparticles' aggregate's surface is exposed to an ultrasound source, the nanoparticle's or nanoparticles' aggregate's material is a material enabling acousto-electric transduction, and wherein the nanoparticle or nanoparticles' aggregate is either neutrally charged in the absence of any coating or is coated with a hydrophilic agent conferring a neutral surface charge to the nanoparticle or nanoparticles' aggregate. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
The present invention relates to compositions and methods for use in medical diagnosis and patient monitoring, typically in the context of therapy, in particular in the context of oncology, to optimize tumor bed local irradiation. It more particularly relates to a biocompatible gel comprising nanoparticle and/or nanoparticle aggregates, wherein: i) the density of each nanoparticle and of each nanoparticle aggregate is at least 7 g/cm3, the nanoparticle or nanoparticles of the aggregate comprising an inorganic material comprising at least one metal element having an atomic number Z of at least 25, more preferably of at least 40, each of said nanoparticle and nanoparticle aggregate being covered with a biocompatible coating; ii) the nanoparticles' and/or nanoparticle aggregates' concentration is of at least about 1% (w/w); and iii) the apparent viscosity at 2 s−1 of the gel comprising nanoparticles and/or nanoparticle aggregates is between about 0.1 Pa·s and about 1000 Pa·s when measured between 20° C. and 37° C.
The present invention relates to the medical field, in particular to the treatment of neurological disorders. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use in prevention or treatment of a neurological disease or at least one symptom thereof in a subject without exposure of the nanoparticle or nanoparticles' aggregate to an electric field, and preferably without exposure thereof to any other external activation source, wherein the nanoparticle's or nanoparticles' aggregate's material is selected from a conductor material, a semiconductor material, an insulator material with a dielectric constant eijk equal to or above 200, and an insulator material with a dielectric constant eijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof without exposure thereof to an electric field, and preferably without exposure thereof to any other external activation source.
A61K 33/00 - Préparations médicinales contenant des ingrédients actifs inorganiques
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
39.
NANOPARTICLES FOR USE IN ENHANCING BRAIN PERFORMANCES OR IN TREATING STRESS
The present invention relates to the medical field, in particular to the enhancement of brain performances and for the treatment of pathological stress. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use in enhancing brain performances or in prevention or treatment of pathological stress in a subject without exposure of the nanoparticle or nanoparticles' aggregate to an electric field, and preferably without exposure thereof to any other external activation source, wherein the nanoparticle's or nanoparticles' aggregate's material is selected from a conductor material, a semiconductor material, an insulator material with a dielectric constant ?ijk equal to or above (200), and an insulator material with a dielectric constant ?ijk equal to or below (100). It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof without exposure thereof to an electric field, and preferably without exposure thereof to any other external activation source such as a light source, a magnetic field, or an ultrasound source.
A61K 47/00 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
40.
NANOPARTICLES FOR USE FOR TREATING A NEURONAL DISORDER
ijkijkijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof without exposure thereof to an electric field, and preferably without exposure thereof to any other external activation source.
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 33/00 - Préparations médicinales contenant des ingrédients actifs inorganiques
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
41.
NANOPARTICLES FOR USE IN ENHANCING BRAIN PERFORMANCES OR IN TREATING STRESS
The present invention relates to the medical field, in particular to the enhancement of brain performances and for the treatment of pathological stress. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use in enhancing brain performances or in prevention or treatment of pathological stress in a subject without exposure of the nanoparticle or nanoparticles' aggregate to an electric field, and preferably without exposure thereof to any other external activation source, wherein the nanoparticle's or nanoparticles' aggregate's material is selected from a conductor material, a semiconductor material, an insulator material with a dielectric constant ɛijk equal to or above (200), and an insulator material with a dielectric constant ɛijk equal to or below (100). It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof without exposure thereof to an electric field, and preferably without exposure thereof to any other external activation source such as a light source, a magnetic field, or an ultrasound source.
A61K 47/00 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
38 - Services de télécommunications
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical products, medical and veterinary
preparations; sanitary products for medical purposes;
dietetic substances for medical use, food for babies;
plasters, materials for dressings; teeth filling materials;
dental impression materials; disinfectants; products for
destroying vermin; fungicides; herbicides; remedies for
human medicine; antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical healthcare
preparations; radiological contrast substances for medical
use; chemical reagents for medical use; bacteriological
preparations for medical use; biological preparations for
medical use; enzymes for medical use; enzyme preparations
for medical use; chemical preparations for medical or
pharmaceutical use; diagnostic products for medical use;
drugs for medical use; medicines for human medicine; tonics
[medicines]; bath preparations for medical use; products
for medical use particularly for tumor diagnosis and
treatment; products for medical use. Scientific research instruments and apparatus for
laboratories; data processing equipment; computers;
chemical reactors (laboratory instruments); scientific,
nautical, surveying, photographic, cinematographic, optical,
weighing, measuring, signaling, checking (supervision),
life-saving and teaching apparatus and instruments;
apparatus and instruments for physics, chemistry, electrical
engineering; computer programs for provision of information
relating to medicine, health and well-being; compact discs
(CDs); DVDs; digital recording media; software (recorded
programs); computer peripheral devices; apparatus for
recording, transmission or reproduction of sound or images;
electronic content recorded on computer media; equipment,
apparatus and articles for infants, namely devices for
improving communication with children with disabilities,
such as devices for visualizing or improving sign language
translation via machine-child communication. Surgical apparatus and instruments; medical apparatus and
instruments; dental apparatus and instruments; veterinary
apparatus and instruments; orthopedic articles and mobility
articles, namely devices for improving immobility related to
cognitive disorders or immobility related to CNS
disabilities, such as cross-section paralysis; massage
apparatus; prostheses; artificial implants and prostheses;
therapeutic and assistance apparatus for handicapped
persons; physical therapy equipment; equipment, apparatus
and articles for infants, namely devices for improving
communication with children with disabilities, such as
hearing devices; radiotherapy apparatus; testing apparatus
for medical use; diagnostic apparatus for medical use;
radiology screens for medical use; X-ray photographs for
medical use; radiological apparatus for medical use;
receptacles for applying medicines; special furniture for
medical use; surgical and medical apparatus and
instruments. Broadcasting of cinematographic films, of radio and
television programs; broadcasting of television programs,
films and other audio and video programs on the Internet. Education; training; entertainment; sporting and cultural
activities; entertainment information; information relating
to education; publication of books; videotape editing;
photography services; organization of competitions
(education or entertainment); organization and conducting of
colloquiums; organization and conducting of conferences;
organization and conducting of congresses; organization of
exhibitions for cultural or educational purposes;
electronic publication of books and journals online;
electronic desktop publishing; entertainment on radio and
television; production of cinematographic films, of radio
and television programs; production of television programs,
films and other audio and video programs on the Internet;
organization and conducting of award ceremonies, concerts,
fashion shows, charity galas; production and organization
of shows; organization of information campaigns (for
cultural or educational purposes); organization of sporting
events; provision of sports facilities; publication of
magazines; ticket agency services; booking of seats for
shows. Scientific and technological services as well as research
and design services; biological research services;
bacteriological research services; evaluations, estimates
and research in scientific and technological fields provided
by engineers, researchers; design, research and development
of new products for third parties; technical project
studies; industrial analysis and research services;
chemical analysis; chemical research; chemistry services;
surveying [engineering work]; technical research;
radiobiology research; research in nanoscience and
nanotechnology, especially applied to medicine; scientific
research; technical research; software installation;
software maintenance; updating of software; software as a
service (SaaS); design and development of computers and
software; information technology (IT) consultancy;
scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine). Healthcare especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy; veterinary
services; information services in the medical field,
namely, provision of information to health professionals and
patients relating to health; medical services including in
the field of nanomedicine; medical information services;
nursing homes; rehabilitation clinic services; rest home
services; opticians' services; alternative medicine
services; beauty salon services; hairdressing salon
services; services of a psychologist; hygienic and beauty
care for human beings or animals; pharmacy and health
consultancy services; medical, hygienic and beauty care;
awareness-raising and information programs in the field of
well-being and health; advice regarding psychology,
psychological assessments; psychological support services;
psychology services; medical assistance; beautician
services; sauna services, solarium services.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
16 - Papier, carton et produits en ces matières
35 - Publicité; Affaires commerciales
38 - Services de télécommunications
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical products, medical and veterinary
preparations; sanitary products for medical purposes;
dietetic substances for medical use, food for babies;
plasters, materials for dressings; teeth filling materials;
dental impression materials; disinfectants; products for
destroying vermin; fungicides; herbicides; remedies for
human medicine; antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical healthcare
preparations; radiological contrast substances for medical
use; chemical reagents for medical use; bacteriological
preparations for medical use; biological preparations for
medical use; enzymes for medical use; enzyme preparations
for medical use; chemical preparations for medical or
pharmaceutical use; diagnostic products for medical use;
drugs for medical use; medicines for human medicine; tonics
[medicines]; bath preparations for medical use; products
for medical use particularly for tumor diagnosis and
treatment; products for medical use. Scientific research instruments and apparatus for
laboratories; data processing equipment; computers;
chemical reactors (laboratory instruments); scientific,
nautical, surveying, photographic, cinematographic, optical,
weighing, measuring, signaling, checking (supervision),
life-saving and teaching apparatus and instruments;
apparatus and instruments for physics, chemistry, electrical
engineering; computer programs for provision of information
relating to medicine, health and well-being; compact discs
(CDs); DVDs; digital recording media; software (recorded
programs); computer peripheral devices; apparatus for
recording, transmission or reproduction of sound or images;
electronic content recorded on computer media; equipment,
apparatus and articles for infants, namely devices for
improving communication with children with disabilities,
such as devices for visualizing or improving sign language
translation via machine-child communication. Surgical apparatus and instruments; medical apparatus and
instruments; dental apparatus and instruments; veterinary
apparatus and instruments; orthopedic articles and mobility
articles, namely devices for improving immobility related to
cognitive disorders or immobility related to CNS
disabilities, such as cross-section paralysis; massage
apparatus; prostheses; artificial implants and prostheses;
therapeutic and assistance apparatus for handicapped
persons; physical therapy equipment; equipment, apparatus
and articles for infants, namely devices for improving
communication with children with disabilities, such as
hearing devices; radiotherapy apparatus; testing apparatus
for medical use; diagnostic apparatus for medical use;
radiology screens for medical use; X-ray photographs for
medical use; radiological apparatus for medical use;
receptacles for applying medicines; special furniture for
medical use; surgical and medical apparatus and
instruments. Office requisites (except furniture); instructional or
teaching material (except apparatus); printing type;
printing blocks; paper; cardboard; boxes of cardboard or
paper; posters; albums; cards; books; newspapers;
prospectuses; pamphlets; calendars; photographs;
stationery; adhesives for stationery or household purposes;
printing products (printed matter); bags (envelopes,
pouches) of paper or plastics, for packaging. Advertising; commercial business management; commercial
administration; office functions; dissemination of
advertising material (leaflets, prospectuses, printed
matter, samples); business management and organization
consultancy; organization of exhibitions for commercial or
advertising purposes; online advertising on a computer
network; rental of advertising time on all communication
media; publication of advertising texts; rental of
advertising space; dissemination of advertisements; public
relations; commercial intermediation services to meet the
needs of individuals; commercial intermediation services. Telecommunications; information on telecommunications;
radio and television broadcasting via wireless or wired
networks; cinematographic, television, radio and videotext
broadcasting; sound, image and data transmission by cable,
satellite, computer (network); provision of user access to
global computer networks; provision of on-line forums;
provision of access to databases; electronic bulletin board
services (telecommunication services); connection by
telecommunications to a global computer network; press
agencies; news (information) agencies; radio program
broadcasting; television broadcasting; teleconferencing
services; videoconferencing services; rental of access time
to global computer networks; provision of access to
information databases; Broadcasting of cinematographic
films, of radio and television programs; broadcasting of
television programs, films and other audio and video
programs on the Internet. Education; training; entertainment; sporting and cultural
activities; entertainment information; information relating
to education; publication of books; videotape editing;
photography services; organization of competitions
(education or entertainment); organization and conducting of
colloquiums; organization and conducting of conferences;
organization and conducting of congresses; organization of
exhibitions for cultural or educational purposes;
electronic publication of books and journals online;
electronic desktop publishing; entertainment on radio and
television; production of cinematographic films, of radio
and television programs; production of television programs,
films and other audio and video programs on the Internet;
organization and conducting of award ceremonies, concerts,
fashion shows, charity galas; production and organization
of shows; organization of information campaigns (for
cultural or educational purposes); organization of sporting
events; provision of sports facilities; publication of
magazines; ticket agency services; booking of seats for
shows. Scientific and technological services as well as research
and design services; biological research services;
bacteriological research services; evaluations, estimates
and research in scientific and technological fields provided
by engineers, researchers; design, research and development
of new products for third parties; technical project
studies; industrial analysis and research services;
chemical analysis; chemical research; chemistry services;
surveying [engineering work]; technical research;
radiobiology research; research in nanoscience and
nanotechnology, especially applied to medicine; scientific
research; technical research; software installation;
software maintenance; updating of software; software as a
service (SaaS); design and development of computers and
software; information technology (IT) consultancy;
scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine). Healthcare especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy; veterinary
services; information services in the medical field,
namely, provision of information to health professionals and
patients relating to health; medical services including in
the field of nanomedicine; medical information services;
nursing homes; rehabilitation clinic services; rest home
services; opticians' services; alternative medicine
services; beauty salon services; hairdressing salon
services; services of a psychologist; hygienic and beauty
care for human beings or animals; pharmacy and health
consultancy services; medical, hygienic and beauty care;
awareness-raising and information programs in the field of
well-being and health; advice regarding psychology,
psychological assessments; psychological support services;
psychology services; medical assistance; beautician
services; sauna services, solarium services.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
38 - Services de télécommunications
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical products, medical and veterinary
preparations; sanitary products for medical purposes;
dietetic substances for medical use, food for babies;
plasters, materials for dressings; teeth filling materials;
dental impression materials; disinfectants; products for
destroying vermin; fungicides; herbicides; remedies for
human medicine; antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical healthcare
preparations; radiological contrast substances for medical
use; chemical reagents for medical use; bacteriological
preparations for medical use; biological preparations for
medical use; enzymes for medical use; enzyme preparations
for medical use; chemical preparations for medical or
pharmaceutical use; diagnostic products for medical use;
drugs for medical use; medicines for human medicine; tonics
[medicines]; bath preparations for medical use; products
for medical use particularly for tumor diagnosis and
treatment; products for medical use. Scientific research instruments and apparatus for
laboratories; data processing equipment; computers;
chemical reactors (laboratory instruments); scientific,
nautical, surveying, photographic, cinematographic, optical,
weighing, measuring, signaling, checking (supervision),
life-saving and teaching apparatus and instruments;
apparatus and instruments for physics, chemistry, electrical
engineering; computer programs for provision of information
relating to medicine, health and well-being; compact discs
(CDs); DVDs; digital recording media; software (recorded
programs); computer peripheral devices; apparatus for
recording, transmission or reproduction of sound or images;
electronic content recorded on computer media; equipment,
apparatus and articles for infants, namely devices for
improving communication with children with disabilities,
such as devices for visualizing or improving sign language
translation via machine-child communication. Surgical apparatus and instruments; medical apparatus and
instruments; dental apparatus and instruments; veterinary
apparatus and instruments; orthopedic articles and mobility
articles, namely devices for improving immobility related to
cognitive disorders or immobility related to CNS
disabilities, such as cross-section paralysis; massage
apparatus; prostheses; artificial implants and prostheses;
therapeutic and assistance apparatus for handicapped
persons; physical therapy equipment; equipment, apparatus
and articles for infants, namely devices for improving
communication with children with disabilities, such as
hearing devices; radiotherapy apparatus; testing apparatus
for medical use; diagnostic apparatus for medical use;
radiology screens for medical use; X-ray photographs for
medical use; radiological apparatus for medical use;
receptacles for applying medicines; special furniture for
medical use; surgical and medical apparatus and
instruments. Broadcasting of cinematographic films, of radio and
television programs; broadcasting of television programs,
films and other audio and video programs on the Internet. Education; training; entertainment; sporting and cultural
activities; entertainment information; information relating
to education; publication of books; videotape editing;
photography services; organization of competitions
(education or entertainment); organization and conducting of
colloquiums; organization and conducting of conferences;
organization and conducting of congresses; organization of
exhibitions for cultural or educational purposes;
electronic publication of books and journals online;
electronic desktop publishing; entertainment on radio and
television; production of cinematographic films, of radio
and television programs; production of television programs,
films and other audio and video programs on the Internet;
organization and conducting of award ceremonies, concerts,
fashion shows, charity galas; production and organization
of shows; organization of information campaigns (for
cultural or educational purposes); organization of sporting
events; provision of sports facilities; publication of
magazines; ticket agency services; booking of seats for
shows. Scientific and technological services as well as research
and design services; biological research services;
bacteriological research services; evaluations, estimates
and research in scientific and technological fields provided
by engineers, researchers; design, research and development
of new products for third parties; technical project
studies; industrial analysis and research services;
chemical analysis; chemical research; chemistry services;
surveying [engineering work]; technical research;
radiobiology research; research in nanoscience and
nanotechnology, especially applied to medicine; scientific
research; technical research; software installation;
software maintenance; updating of software; software as a
service (SaaS); design and development of computers and
software; information technology (IT) consultancy;
scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine). Healthcare especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy; veterinary
services; information services in the medical field,
namely, provision of information to health professionals and
patients relating to health; medical services including in
the field of nanomedicine; medical information services;
nursing homes; rehabilitation clinic services; rest home
services; opticians' services; alternative medicine
services; beauty salon services; hairdressing salon
services; services of a psychologist; hygienic and beauty
care for human beings or animals; pharmacy and health
consultancy services; medical, hygienic and beauty care;
awareness-raising and information programs in the field of
well-being and health; advice regarding psychology,
psychological assessments; psychological support services;
psychology services; medical assistance; beautician
services; sauna services, solarium services.
45.
Inorganic nanoparticles compositions in combination with ionizing radiations for treating cancer
The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cancerous cells, tissues or organs. It more particularly relates to nanoparticles which can generate a surprisingly efficient therapeutic effect, when concentrated inside the tumor and exposed to ionizing radiations. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
38 - Services de télécommunications
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical products, medical and veterinary
preparations; sanitary products for medical purposes;
dietetic substances for medical use, food for babies;
plasters, materials for dressings; teeth filling materials;
dental impression materials; disinfectants; products for
destroying vermin; fungicides; herbicides; remedies for
human medicine; antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical healthcare
preparations; radiological contrast substances for medical
use; chemical reagents for medical use; bacteriological
preparations for medical use; biological preparations for
medical use; enzymes for medical use; enzyme preparations
for medical use; chemical preparations for medical or
pharmaceutical use; diagnostic products for medical use;
drugs for medical use; medicines for human medicine; tonics
[medicines]; bath preparations for medical use; products
for medical use particularly for tumor diagnosis and
treatment; products for medical use. Scientific research instruments and apparatus for
laboratories; data processing equipment; computers;
chemical reactors (laboratory instruments); scientific,
nautical, surveying, photographic, cinematographic, optical,
weighing, measuring, signaling, checking (supervision),
life-saving and teaching apparatus and instruments;
apparatus and instruments for physics, chemistry, electrical
engineering; computer programs for provision of information
relating to medicine, health and well-being; compact discs
(CDs); DVDs; digital recording media; software (recorded
programs); computer peripheral devices; apparatus for
recording, transmission or reproduction of sound or images;
electronic content recorded on computer media; equipment,
apparatus and articles for infants, namely devices for
improving communication with children with disabilities,
such as devices for visualizing or improving sign language
translation via machine-child communication. Surgical apparatus and instruments; medical apparatus and
instruments; dental apparatus and instruments; veterinary
apparatus and instruments; orthopedic articles and mobility
articles, namely devices for improving immobility related to
cognitive disorders or immobility related to CNS
disabilities, such as cross-section paralysis; massage
apparatus; prostheses; artificial implants and prostheses;
therapeutic and assistance apparatus for handicapped
persons; physical therapy equipment; equipment, apparatus
and articles for infants, namely devices for improving
communication with children with disabilities, such as
hearing devices; radiotherapy apparatus; testing apparatus
for medical use; diagnostic apparatus for medical use;
radiology screens for medical use; X-ray photographs for
medical use; radiological apparatus for medical use;
receptacles for applying medicines; special furniture for
medical use; surgical and medical apparatus and
instruments. Broadcasting of cinematographic films, of radio and
television programs; broadcasting of television programs,
films and other audio and video programs on the Internet. Education; training; entertainment; sporting and cultural
activities; entertainment information; information relating
to education; publication of books; videotape editing;
photography services; organization of competitions
(education or entertainment); organization and conducting of
colloquiums; organization and conducting of conferences;
organization and conducting of congresses; organization of
exhibitions for cultural or educational purposes;
electronic publication of books and journals online;
electronic desktop publishing; entertainment on radio and
television; production of cinematographic films, of radio
and television programs; production of television programs,
films and other audio and video programs on the Internet;
organization and conducting of award ceremonies, concerts,
fashion shows, charity galas; production and organization
of shows; organization of information campaigns (for
cultural or educational purposes); organization of sporting
events; provision of sports facilities; publication of
magazines; ticket agency services; booking of seats for
shows. Scientific and technological services as well as research
and design services; biological research services;
bacteriological research services; evaluations, estimates
and research in scientific and technological fields provided
by engineers, researchers; design, research and development
of new products for third parties; technical project
studies; industrial analysis and research services;
chemical analysis; chemical research; chemistry services;
surveying [engineering work]; technical research;
radiobiology research; research in nanoscience and
nanotechnology, especially applied to medicine; scientific
research; technical research; software installation;
software maintenance; updating of software; software as a
service (SaaS); design and development of computers and
software; information technology (IT) consultancy;
scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine). Healthcare especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy; veterinary
services; information services in the medical field,
namely, provision of information to health professionals and
patients relating to health; medical services including in
the field of nanomedicine; medical information services;
nursing homes; rehabilitation clinic services; rest home
services; opticians' services; alternative medicine
services; beauty salon services; hairdressing salon
services; services of a psychologist; hygienic and beauty
care for human beings or animals; pharmacy and health
consultancy services; medical, hygienic and beauty care;
awareness-raising and information programs in the field of
well-being and health; advice regarding psychology,
psychological assessments; psychological support services;
psychology services; medical assistance; beautician
services; sauna services, solarium services.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Products for medical use especially for the treatment of
brain diseases and disorders; preparation for the diagnosis
and treatment of brain diseases and disorders; preparation
for medical use especially for modifying the bioavailability
of therapeutic agents; preparation for medical use
especially for the diagnosis and treatment of tumors;
preparation for medical use particularly for the treatment
of Parkinson's disease, Alzheimer's disease, epilepsy and
all types of neurological and neuropsychiatric diseases and
disorders; preparation for medical use especially for the
treatment of symptoms of Parkinson's disease, symptoms of
Alzheimer's disease, symptoms of epilepsy and symptoms
relating to all kinds of neurological and neuropsychiatric
diseases and disorders; preparation for the diagnosis and
treatment of neurological disorders and diseases using deep
brain stimulation, electrical transcranial stimulation,
transcranial direct-current stimulation, transcranial
magnetic stimulation, any form of electromagnetic
stimulation (light, magnetic field, electric field), radio
frequency or ultrasound stimulation; health products;
radiological contrast substances for medical use;
nanoparticles for medical use; nanomaterial-based
preparation for the delivery of therapeutic agents; chemical
reagents for medical use; bacteriological preparations for
medical use; biological preparations for medical use;
enzymes for medical use; enzyme preparations for medical
use; chemical preparations for medical or pharmaceutical
use; diagnostic products for medical use; drugs for medical
use; medicines for human medicine; tonics (medicines);
antibiotics; antiseptics; chemico-pharmaceutical products;
pharmaceutical products; dietetic substances for medical
use; remedies for human medicine. Surgical and medical apparatus and instruments especially
for the diagnosis and treatment of tumors; surgical and
medical apparatus and instruments especially for monitoring
and modifying metabolic functions; surgical and medical
apparatus and instruments especially for the diagnosis and
treatment of brain diseases and disorders; surgical and
medical apparatus and instruments for deep brain
stimulation, electrical transcranial stimulation,
transcranial direct-current stimulation, transcranial
magnetic stimulation, any form of electromagnetic
stimulation (light, magnetic field, electric field), radio
frequency or ultrasound stimulation; apparatus for the
delivery of diagnostic or therapeutic agents; testing
apparatus for medical use; diagnostic apparatus for medical
use; apparatus for the recording of electrical brain
activity (electrodes, electroencephalograph, micro-electrode
arrays); apparatus for electrophysiology; apparatus for
neuronal modeling. Scientific and technological services and research and
design especially in the field of nanomedicine
(nanotechnology applied to medicine); biological research
services; bacteriological research services;
electrophysiological research; research in neuronal
modeling; evaluations, estimates and research in scientific
and technological fields provided by engineers and
researchers; design and development of new products (for
third parties); technical project studies; industrial
analysis and research services; chemical analysis;
chemical research; chemistry services; surveying
(engineering work); research and development of new products
for others; technical research; research in the field of
neuroscience; research in radio-biology; research in
nanoscience and nanotechnology, especially applied to
medicine. Healthcare especially in the field of nanomedicine; medical
services especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy.
48.
Methods of treatment utilizing biocompatible nanoparticles and therapeutic agents
The invention pertains to a therapeutic, prophylactic or diagnostic method comprising, administering a pharmaceutical compound followed by administering a biocompatible nanoparticle comprising an oligomer of albumin, wherein the longest or largest dimension of the nanoparticle is between about 4 nm and about 500 nm. In preferred embodiments, administering the biocompatible nanoparticles is performed between more than 5 minutes and about 72 hours after administering the pharmaceutical compound. In particular embodiments, the pharmaceutical compound is a pharmaceutical antibody, such as a monoclonal antibody, a drug conjugated antibody, an engineered antibody and a multispecific antibody. According to the methods of the invention, administering the biocompatible nanoparticle comprising oligomers of albumin after administering the pharmaceutical compound maintains or increases the therapeutic benefit and reduces toxicity of the pharmaceutical compound when compared to the therapeutic benefit and toxicity induced by administering the pharmaceutical compound alone.
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
C07K 16/22 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des facteurs de croissance
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Products for medical use especially for the treatment of
brain diseases and disorders; preparation for the diagnosis
and treatment of brain diseases and disorders; preparation
for medical use especially for modifying the bioavailability
of therapeutic agents; preparation for medical use
especially for the diagnosis and treatment of tumors;
preparation for medical use particularly for the treatment
of Parkinson's disease, Alzheimer's disease, epilepsy and
all types of neurological and neuropsychiatric diseases and
disorders; preparation for medical use especially for the
treatment of symptoms of Parkinson's disease, symptoms of
Alzheimer's disease, symptoms of epilepsy and symptoms
relating to all kinds of neurological and neuropsychiatric
diseases and disorders; preparation for the diagnosis and
treatment of neurological disorders and diseases using deep
brain stimulation, electrical transcranial stimulation,
transcranial direct-current stimulation, transcranial
magnetic stimulation, any form of electromagnetic
stimulation (light, magnetic field, electric field), radio
frequency or ultrasound stimulation; health care products;
radiological contrast substances for medical use;
nanoparticles for medical use; preparation based on
nanomaterials for the delivery of therapeutic agents;
chemical reagents for medical use; bacteriological
preparations for medical use; biological preparations for
medical use; enzymes for medical use; enzyme preparations
for medical use; chemical preparations for medical or
pharmaceutical use; diagnostic products for medical use;
drugs for medical use; medicines for human medicine; tonics
(medicines); antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical products;
dietetic substances for medical use; remedies for human
medicine. Surgical and medical apparatus and instruments especially
for the diagnosis and treatment of tumors; surgical and
medical apparatus and instruments especially for monitoring
and modifying metabolic functions; surgical and medical
apparatus and instruments especially for the diagnosis and
treatment of brain diseases and disorders; surgical and
medical apparatus and instruments for deep brain
stimulation, electrical transcranial stimulation,
transcranial direct-current stimulation, transcranial
magnetic stimulation, any form of electromagnetic
stimulation (light, magnetic field, electric field), radio
frequency or ultrasound stimulation; apparatus for the
delivery of diagnostic or therapeutic agents; testing
apparatus for medical use; diagnostic apparatus for medical
use; apparatus for the recording of electrical brain
activity (electrodes, electroencephalograph, micro-electrode
arrays); apparatus for electrophysiology; apparatus for
neuronal modeling. Scientific and technological services and research and
design especially in the field of nanomedicine
(nanotechnology applied to medicine); biological research
services; bacteriological research services;
electrophysiological research; research in neuronal
modeling; evaluations, estimates and research in scientific
and technological fields provided by engineers and
researchers; design and development of new products (for
third parties); technical project studies; industrial
analysis and research services; chemical analysis;
chemical research; chemistry services; surveying
(engineering work); research and development of new products
for others; technical research; research in the field of
neuroscience; research in radio-biology; research in
nanoscience and nanotechnology, especially applied to
medicine. Healthcare especially in the field of nanomedicine; medical
services especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Products for medical use especially for metabolic pathways;
products for medical use especially for the diagnosis and
treatment of tumors; preparations for medical use
especially for modifying the bioavailability of therapeutic
agents; preparations for medical use especially for
modifying liver functions; Preparations for medical use for
modifying the functions of the reticuloendothelial system;
preparations made with nanomaterials for the delivery of
therapeutic agents; nanoparticles for medical use;
chemical reagents for medical use; bacteriological
preparations for medical use; biological preparations for
medical use; enzymes for medical use; enzyme preparations
for medical use; chemical preparations for medical or
pharmaceutical use; diagnostic products for medical use;
drugs for medical use; medicines for human medicine; tonics
(medicines); antibiotics; antiseptics;
chemico-pharmaceutical products; pharmaceutical products;
dietetic substances for medical use; remedies for human
medicine. Surgical and medical apparatus and instruments especially
for the diagnosis and treatment of tumors; Surgical and
medical apparatus and instruments especially for monitoring
and modifying metabolic functions; apparatus for modifying
the functions of the reticuloendothelial system; apparatus
for modulating liver functions; apparatus for the delivery
of therapeutic or diagnostic agents; apparatus for
modulating hepatic blood flow; testing apparatus for
medical use; diagnostic apparatus for medical use. Scientific and technological services and research and
design especially in the field of nanomedicine
(nanotechnology applied to medicine); biological research
services; bacteriological research services; evaluations,
estimates and research in scientific and technological
fields provided by engineers and researchers; design and
development of new products (for third parties); technical
project studies; industrial analysis and research services;
chemical analysis; chemical research; chemistry services;
surveying (engineering work); research and development of
new products for others; technical research; radiobiology
research; research in nanoscience and nanotechnology,
especially applied to medicine. Healthcare especially in the field of nanomedicine; medical
services especially in the field of nanomedicine; hospital
services; medical assistance; physiotherapy.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical products for medical use, namely, for the treatment of brain diseases and disorders; Pharmaceutical preparation for the diagnosis and treatment of brain diseases and disorders; Pharmaceutical preparation for medical use namely, for modifying the bioavailability of therapeutic agents; Pharmaceutical preparation for medical use namely, for the diagnosis and treatment of tumors; Pharmaceutical preparation for medical use particularly for the treatment of Parkinson's disease, Alzheimer's disease, epilepsy and all types of neurological and neuropsychiatric diseases and disorders; Pharmaceutical preparation for medical use namely, for [ the treatment of ] * treating the * symptoms of Parkinson's disease, symptoms of Alzheimer's disease, symptoms of epilepsy and symptoms [ relating ] * related * to [ all kinds ] * any type * of neurological and neuropsychiatric [ diseases and disorders ] * disorders and diseases * ; Pharmaceutical preparation for the diagnosis and treatment of neurological disorders and diseases for use with deep brain stimulation, electrical transcranial stimulation, transcranial direct-current stimulation, transcranial magnetic stimulation, any form of electromagnetic stimulation in the nature of light, magnetic field, electric field, radio frequency or ultrasound stimulation; health products, namely, pharmaceutical preparations for central nervous systems disorder treatment; radiological contrast substances for medical use; nanoparticles for medical use, namely, nanomaterial-based chemical preparations for medical and pharmaceutical purpose for the treatment of cancer, central nervous system disorder, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases ; Drug delivery agents in the form of nanomaterial-based preparation for the delivery of therapeutic agents; chemical reagents for medical use; bacteriological preparations for medical use; biological preparations for medical use, namely, for the treatment of cancer, central nervous system disorder, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; enzymes for medical use; enzyme preparations for medical use; chemical preparations for medical or pharmaceutical use, namely, for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; diagnostic products for medical use, namely, diagnostic preparations for medical purposes; drugs for medical use, namely, nanomaterial-based pharmaceutical preparation of active ingredients for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicines for human medicine, namely, medical preparations for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; tonics being medicines, namely, medicinal herbal preparations; antibiotics; antiseptics; chemico-pharmaceutical products, namely, chemical preparations for pharmaceutical or medical purposes, namely, for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; pharmaceutical products, namely, pharmaceutical products for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases * for human use * ; [ dietetic] * dietary * substances for medical use, namely, dietetic foods adapted for medical purposes; remedies for human medicine, namely, natural remedy preparations for the treatment of gastrointestinal conditions, hormonal and chemical imbalances, and sleep disorder [ Surgical and medical apparatus and instruments especially for the diagnosis and treatment of tumors, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely, ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor; surgical and medical apparatus and instruments especially for monitoring and modifying metabolic functions, namely, heart rate monitoring apparatus, medical apparatus and instruments for monitoring vital signs, blood properties and respiratory events, devices for monitoring blood glucose for medical purposes; surgical and medical apparatus and instruments especially for the diagnosis and treatment of brain diseases and disorders, namely, medical imaging devices for the brain, medical devices for monitoring vital signs, blood properties and respiratory events, medical devices for monitoring brain's electrical activity, medical devices for monitoring cognitive and motor functions during neurosurgery, medical apparatus and instrument for diagnostic use, namely, apparatus for medical diagnostic testing in the fields of neurodegenerative diseases; surgical apparatus and instruments for deep brain stimulation, electrical transcranial stimulation, transcranial direct-current stimulation, transcranial magnetic stimulation, any form of electromagnetic stimulation, namely, light, magnetic field, electric field, radio frequency or ultrasound stimulation, namely, low level laser therapy, near-infrared light-emitting devices, electric devices for deep brain stimulation, wire coil devices for magnetic stimulation, scalp electrodes for transcranial direct-current stimulation, medical radiofrequency apparatus, medical ultrasound apparatus, electrical stimulation apparatus for scalp, nerves, skin, and muscles for physical therapy purposes; apparatus for the delivery of diagnostic or therapeutic agents, namely, medical apparatus and units for dosage, measuring and monitoring, namely, drug delivery devices and systems and organ oxygenation and perfusion apparatus; testing apparatus for medical use, namely, medical imaging devices for monitoring oxygen level in the brain, medical imaging devices for monitoring glucose level in the brain, medical imaging devices for monitoring proteins level in the brain, microdialysis devices for monitoring proteins level in the cerebrospinal fluid, medical devices for monitoring the brain's electrical activity; diagnostic apparatus for medical use, namely, medical diagnostic apparatus for testing the brain's electrical activity, oxygen level in the brain, glucose level in the brain, proteins level in the brain; Medical apparatus for the recording of electrical brain activity, namely, electrodes, electroencephalograph, micro-electrode arrays; apparatus for electrophysiology, namely, medical electrodes for patch-clamp devices, current-clamp devices, voltage-clamp devices, micro-electrode arrays devices; apparatus for neuronal modeling, namely, medical imaging apparatus incorporating medical imaging software and computational software sold as a unit therewith ] Scientific and technological services namely, scientific research and research and design in the field of nanomedicine in the nature of nanotechnology applied to medicine; biological research services; bacteriological research services; electrophysiological research; research in neuronal modeling; Testing, analysis and evaluation of service providers to determine conformity with established accreditation standards, namely, evaluations, estimates and research in scientific and technological fields provided by engineers and researchers; design and development of new products for third parties; technical project studies, namely, technical research in the field of pharmaceutical project studies; industrial analysis and research services in the field of biomedical research; chemical analysis; chemical research; chemistry services, namely, chemistry consultation; surveying, namely, conducting engineering surveys; research and development of new products for others; technical research in the field of pharmaceutical studies; research in the field of neuroscience; research in radio-biology; research in nanoscience and nanotechnology, especially applied to medicine Healthcare especially in the field of nanomedicine; medical services especially in the field of nanomedicine; hospital services; medical assistance; physiotherapy
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical products for medical use, namely, for the treatment of brain diseases and disorders; Pharmaceutical preparation for the diagnosis and treatment of brain diseases and disorders; Pharmaceutical preparation for medical use namely, for modifying the bioavailability of therapeutic agents; Pharmaceutical preparation for medical use namely, for the diagnosis and treatment of tumors; Pharmaceutical preparation for medical use particularly for the treatment of Parkinson's disease, Alzheimer's disease, epilepsy and all types of neurological and neuropsychiatric diseases and disorders; Pharmaceutical preparation for medical use namely, for [ the treatment of ] * treating the * symptoms of Parkinson's disease, symptoms of Alzheimer's disease, symptoms of epilepsy and symptoms [ relating to all kinds ] * related to any type * of neurological and neuropsychiatric [ diseases and disorders ] * disorders and diseases * ; Pharmaceutical preparation for the diagnosis and treatment of neurological disorders and diseases for use with deep brain stimulation, electrical transcranial stimulation, transcranial direct-current stimulation, transcranial magnetic stimulation, any form of electromagnetic stimulation in the nature of light, magnetic field, electric field, radio frequency or ultrasound stimulation; health * care * products, namely, pharmaceutical preparations for central nervous systems disorder treatment; radiological contrast substances for medical use; nanoparticles for medical use, namely, nanomaterial-based chemical preparations for medical and pharmaceutical purpose for the treatment of cancer, central nervous system disorder, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases ; Drug delivery agents in the form of nanomaterial-based preparation for the delivery of therapeutic agents; chemical reagents for medical use; bacteriological preparations for medical use; biological preparations for medical use, namely, for the treatment of cancer, central nervous system disorder, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; enzymes for medical use; enzyme preparations for medical use; chemical preparations for medical or pharmaceutical use, namely, for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; diagnostic products for medical use, namely, diagnostic preparations for medical purposes; drugs for medical use, namely, nanomaterial-based pharmaceutical preparation of active ingredients for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicines for human medicine, namely, medical preparations for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; tonics being medicines, namely, medicinal herbal preparations; antibiotics; antiseptics; chemico-pharmaceutical products, namely, chemical preparations for pharmaceutical or medical purposes, namely, for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; pharmaceutical products, namely, pharmaceutical products for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases * for human use * ; dietetic substances for medical use, namely, dietetic foods adapted for medical purposes; remedies for human medicine, namely, natural remedy preparations for the treatment of gastrointestinal conditions, hormonal and chemical imbalances, and sleep disorder [ Surgical and medical apparatus and instruments especially for the diagnosis and treatment of tumors, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely, ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor; surgical and medical apparatus and instruments especially for monitoring and modifying metabolic functions, namely, heart rate monitoring apparatus, medical apparatus and instruments for monitoring vital signs, blood properties and respiratory events, devices for monitoring blood glucose for medical purposes; surgical and medical apparatus and instruments especially for the diagnosis and treatment of brain diseases and disorders, namely, medical imaging devices for the brain, medical devices for monitoring vital signs, blood properties and respiratory events, medical devices for monitoring brain's electrical activity, medical devices for monitoring cognitive and motor functions during neurosurgery, medical apparatus and instrument for diagnostic use, namely, apparatus for medical diagnostic testing in the fields of neurodegenerative diseases; surgical apparatus and instruments for deep brain stimulation, electrical transcranial stimulation, transcranial direct-current stimulation, transcranial magnetic stimulation, any form of electromagnetic stimulation, namely, light, magnetic field, electric field, radio frequency or ultrasound stimulation, namely, low level laser therapy, near-infrared light-emitting devices, electric devices for deep brain stimulation, wire coil devices for magnetic stimulation, scalp electrodes for transcranial direct-current stimulation, medical radiofrequency apparatus, medical ultrasound apparatus, electrical stimulation apparatus for scalp, nerves, skin, and muscles for physical therapy purposes; apparatus for the delivery of diagnostic or therapeutic agents, namely, medical apparatus and units for dosage, measuring and monitoring, namely, drug delivery devices and systems and organ oxygenation and perfusion apparatus; testing apparatus for medical use, namely, medical imaging devices for monitoring oxygen level in the brain, medical imaging devices for monitoring glucose level in the brain, medical imaging devices for monitoring proteins level in the brain, microdialysis devices for monitoring proteins level in the cerebrospinal fluid, medical devices for monitoring the brain's electrical activity; diagnostic apparatus for medical use, namely, medical diagnostic apparatus for testing the brain's electrical activity, oxygen level in the brain, glucose level in the brain, proteins level in the brain; Medical apparatus for the recording of electrical brain activity, namely, electrodes, electroencephalograph, micro-electrode arrays; apparatus for electrophysiology, namely, medical electrodes for patch-clamp devices, current-clamp devices, voltage-clamp devices, micro-electrode arrays devices; apparatus for neuronal modeling, namely, medical imaging apparatus incorporating medical imaging software and computational software sold as a unit therewith ] Scientific and technological services namely, scientific research and research and design in the field of nanomedicine in the nature of nanotechnology applied to medicine; biological research services; bacteriological research services; electrophysiological research; research in neuronal modeling; Testing, analysis and evaluation of service providers to determine conformity with established accreditation standards, namely, evaluations, estimates and research in scientific and technological fields provided by engineers and researchers; design and development of new products for third parties; technical project studies, namely, technical research in the field of pharmaceutical project studies; industrial analysis and research services in the field of biomedical research; chemical analysis; chemical research; chemistry services, namely, chemistry consultation; surveying, namely, conducting engineering surveys; research and development of new products for others; technical research in the field of pharmaceutical studies; research in the field of neuroscience; research in radio-biology; research in nanoscience and nanotechnology, especially applied to medicine Healthcare especially in the field of nanomedicine; medical services especially in the field of nanomedicine; hospital services; medical assistance; physiotherapy
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Products for medical use especially for metabolic pathways, namely, enzyme substrates and enzyme inhibitors; products for medical use especially for the diagnosis and treatment of tumors, namely, diagnostic preparation for medical purposes for the diagnosis of tumors and therapeutic pharmaceutical preparations for medical purposes for the treatment of tumors and rare hepatic diseases; preparations for medical use especially for modifying the bioavailability of therapeutic agents, namely, lipidic and polymeric formulation for drug delivery in the nature of drug delivery agents in the form of nanoparticles, nanovesicles, particles, vesicles, dissolvable films, coatings for tablets and hydrogels that facilitate the delivery of pharmaceutical preparations; preparations for medical use especially for modifying liver functions, namely, pharmaceutical preparations for the treatment of liver diseases and disorders and pharmaceutical preparations to alter hepatic metabolization pathways; preparations for medical use for modifying the functions of the reticuloendothelial system, namely, pharmaceutical preparations for the treatment of reticuloendothelial system diseases and disorders and pharmaceutical preparations to alter reticuloendothelial system endocytosis pathways; preparations made with nanomaterials for the delivery of therapeutic agents, namely, drug delivery agents in the form of enterally, parenterally in the nature of intravenous, or topically administered nanomaterials that facilitate the delivery of pharmaceutical preparations; chemical reagents for medical use; bacteriological preparations for medical use; biological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiological, immunological, gastrointestinal, metabolic and infection diseases; enzymes for medical use; enzyme preparations for medical use; chemical preparations for medical or pharmaceutical use, namely, for the treatment of cancer, central nervous system disorder, cardiological, immunological, gastrointestinal, metabolic and infection diseases; diagnostic products for medical use, namely, diagnostic preparations for medical purposes; drugs for medical use, namely, medical preparations for the treatment of cancer, central nervous system disorder, cardiological, immunological, gastrointestinal, metabolic and infectious diseases; medicines for human medicine, namely, medical preparations for the treatment of cancer, central nervous system disorder, cardiological, immunological, gastrointestinal, metabolic and infectious diseases; tonics medicines, namely, medical herbal preparations; antibiotics; antiseptics; chemico-pharmaceutical products for the treatment of the treatment of cancer, central nervous system disorder, cardiological, immunological, gastrointestinal, metabolic and infection diseases; pharmaceutical products, namely, drug delivery agents consisting of compounds that facilitate delivery of a wide range of pharmaceuticals; dietetic substances for medical use, namely, dietetic foods adapted for medical purposes; remedies for human medicine, namely, natural remedy preparations for the treatment of gastrointestinal conditions, hormonal and chemical imbalances, and sleep disorders Surgical and medical apparatus and instruments especially for the diagnosis and treatment of tumors; Surgical and medical apparatus and instruments especially for monitoring and modifying metabolic functions; Apparatus for modifying the functions of the reticuloendothelial system, namely, medical apparatus and instruments for use in endovascular and cardiovascular procedures; Apparatus for modulating liver functions, namely, medical apparatus and instruments for use in measuring, quantifying and assessing liver health and oxygenation and perfusion apparatus in the nature of perfusion pumps for liver transplantation; Apparatus for the delivery of therapeutic or diagnostic agents, namely, medical apparatus and units for dosage, measuring and monitoring, in the nature of drug delivery devices and systems, and organ oxygenation and perfusion apparatus in the nature of perfusion pumps; Apparatus for modulating hepatic blood flow, namely, organ perfusion apparatus in the nature of perfusion pumps; Testing apparatus for medical use in the nature of medical diagnostic apparatus for testing cancer calls, DNA, organ oxygenation and blood sugar levels; Diagnostic apparatus for medical use for testing cancer calls, DNA, organ oxygenation and blood sugar levels Scientific and technological services, namely, research and design especially in the field of nanomedicine, in the nature of nanotechnology applied to medicine; Biological research services; Bacteriological research services; Evaluations, estimates and research in scientific and technological fields provided by engineers and researchers, namely, conducting early evaluations in the field of new pharmaceuticals; Design and development of new products for third parties in the field of pharmaceutical preparations and diagnostic devices design; Technical research in the field of pharmaceutical project studies; Industrial analysis and research services, namely, biomedical research services; Chemical analysis; Chemical research; Chemistry services, namely, chemistry consultation; Surveying, namely, engineering work; Research and development of new products for others; Technical research in the field of pharmaceutical studies; Biological research, namely, radiobiology research, biological, pharmacokinetic, pharmacodynamic and immunological evaluation and toxicological evaluation; Medical research, namely, research in nanoscience and nanotechnology, especially applied to medicine Healthcare especially in the field of nanomedicine; medical services especially in the field of nanomedicine; hospital services; medical assistance; physiotherapy
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
16 - Papier, carton et produits en ces matières
35 - Publicité; Affaires commerciales
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Information on telecommunications; radio and television broadcasting via wireless or wired networks; video broadcasting featuring cinematographic content, video broadcasting featuring videotext content; electronic transmission of sound, image and data by cable, satellite, computer networks; provision of user access to global computer networks; provision of on-line forums in the field of biotechnologies science for humans and nanomedicine; provision of access to databases; electronic bulletin board services; press agencies, namely, transmission of news; radio program broadcasting; television broadcasting; teleconferencing services; videoconferencing services; rental of access time to global computer networks; provision of access to information databases Pharmaceutical preparations for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases, medical products for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases and veterinary diagnostic preparations; sanitary products for medical purposes, namely, sanitary pads, sanitary towels, sanitary napkins; dietetic substances for medical use, namely, dietetic foods adapted for medical purposes; food for babies; medical plasters; materials for dressings namely, wound dressings, sterilized dressing, Burn dressings; teeth filling materials; dental impression materials; disinfectants; preparations for destroying vermin; fungicides; herbicides; remedies for human medicine in the nature of natural remedy preparations for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, and sleep disorders; antibiotics; antiseptics; chemico-pharmaceutical products, namely, chemical preparations for pharmaceutical or medical purposes, namely, for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; pharmaceutical healthcare preparations for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; radiological contrast substances for medical use; chemical reagents for medical use; bacteriological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; biological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; enzyme preparations for medical purpose use; chemical preparations for medical or pharmaceutical use, namely, chemical preparations for pharmaceutical or medical purposes, namely, for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; diagnostic testing products for medical use in the form of reagents and assays for use in disease testing; drugs for medical use namely, biotechnology science-based pharmaceutical preparation of active ingredients for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicines for human consumption for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicated tonics for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; bath preparations for medical use Scientific research instruments, namely, medical laboratory research instruments for DNA analysis; data processing equipment, namely, data processors; computers; Laboratory chemical reactors; downloadable computer programs providing a searchable database of information relating to medicine, health and well-being; pre-recorded compact discs in the fields of nanotechnology and biotechnology; digital recording media, namely, pre-recorded video cassettes, digital video discs, digital versatile discs, downloadable audio and video recordings, DVDs, and high definition digital discs in the fields of nanotechnology and biotechnology; computer peripheral devices; apparatus for recording, transmission or reproduction of sound or images; equipment, apparatus and articles for infants, namely, computer hardware and software for operating devices for visualizing or improving sign language translation via machine-child communication for the purpose of improving communication with children with disabilities Surgical apparatus and instruments; medical apparatus and instruments for the diagnosis and treatment of human diseases such as cancer, CNS-disorders, orthopedics and gastro-intestinal disorders, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely, ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor; orthopedic articles and mobility articles, namely, devices for improving immobility related to cognitive disorders or immobility related to CNS disabilities, such as cross-section paralysis; massage apparatus; prostheses, namely, prosthetic tissues for parietal, visceral and vascular use; artificial implants and prostheses, namely, artificial prosthetic tissues for parietal, visceral and vascular use; therapeutic and assistance apparatus for handicapped persons, namely, invalid hoists and invalid walkers; physical therapy equipment, namely, weight lifting machines for physical therapy; equipment, apparatus and articles for infants, namely, hearing aids for improving communication with children with disabilities; radiotherapy apparatus; immunochemical testing apparatus for medical use; diagnostic apparatus for medical use to detect cancer, CNS-disorders, orthopedics, and gastro-intestinal disorders; radiology screens for medical use; X-ray photographs for medical use; radiological apparatus for medical use; receptacles for applying medicines, namely, Medical fluid injectors; special furniture for medical use; surgical and medical apparatus and instruments, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely, ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor Office requisites, namely, staplers; printed instructional and teaching material in the field of biotechnologies science for humans and nanomedicine; printing type; printing blocks; paper; cardboard; boxes of cardboard or paper; posters; photo albums; blank cards; books in the field of biotechnologies science for humans and nanomedicine; newspapers in the field of biotechnologies science for humans and nanomedicine; pamphlets in the field of biotechnologies science for humans and nanomedicine; calendars; photographs; stationery; adhesives for stationery or household purposes; paper and plastic bags for packaging Advertising; commercial business management; commercial administration; office functions; dissemination of advertising material, namely, leaflets, prospectuses, printed matter, and samples; business management and organization consultancy; organization of exhibitions for commercial or advertising purposes; online advertising on a computer network; rental of advertising time on all communication media; publication of advertising texts; rental of advertising space; dissemination of advertisements; public relations; commercial intermediation services relating to the matching of potential private investors with entrepreneurs needing funding Education services, namely, conducting programs, classes and seminars in the fields of biotechnology and nanotechnology; training for medical professionals and non-medical professionals in the fields of biotechnology and nanotechnology; organising sporting and cultural activities, namely, organizing community sporting and cultural events; entertainment information; information relating to educational services; publication of books; videotape editing; photography services; organization of sport competitions; organization of educational competitions in the fields of biotechnology and nanotechnology; organizing and conducting of educational colloquiums; organization and conducting of educational conferences; organizing and conducting of educational congresses; organization of exhibitions for cultural or educational purposes; provide online publication of books and journals; electronic desktop publishing; production of cinematographic films, of radio and television programs; production of television programs and films on the Internet; organization and conducting of award ceremonies, concerts, fashion shows, charity galas; organization of sporting events; provision of sports facilities; publication of magazines; ticket agency services; booking of seats for shows Scientific and technological services, namely, research and design services in the field of biotechnologies science for humans, nanomedicine in the nature of nanotechnology applied to medicine; biological research services; bacteriological research services; testing, analysis and evaluation of service providers to determine conformity with established accreditation standards, namely, evaluations, estimates and research in scientific and technological fields provided by engineers, researchers; design, research and development of new products for third parties; technical project studies, namely, technical research in the field of pharmaceutical project studies; industrial research services in the field of biomedical research; chemical analysis; chemical research; chemistry services, namely, chemistry consultation; surveying, namely, conducting engineering surveys; technical research in the field of pharmaceutical studies; radiobiology research; research in nanoscience and nanotechnology, especially applied to medicine; scientific research; computer software installation; computer software maintenance; updating of computer software; software as a service (SaaS) featuring software for providing a searchable database featuring information relating to medicine, health and well-being; software as a service (SaaS) featuring software for operating devices for visualizing or improving sign language translation via machine-child communication for the purpose of improving communication with children with disabilities; design and development of computers and software; information technology (IT) consultancy; scientific and technological services namely, research and design services particularly in the field of biotechnologies science for humans and nanomedicine Healthcare in the field of nanomedicine; hospital services; veterinary services; information services in the medical field, namely, provision of information to health professionals and patients relating to health; medical services in the field of nanomedicine; medical information services; nursing homes services; rest home services; opticians' services; alternative medicine services; beauty salon services; hairdressing salon services; hygienic and beauty care for human beings or animals; pharmaceutical consultation; health consultancy services; providing awareness and information in the field of wellness and health; beautician services; sauna services, solarium services
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Broadcasting of cinematographic films, of radio and television programs; broadcasting of television programs, films and other audio and video programs on the Internet Pharmaceutical products for the treatment of gastrointestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; diagnostic preparations for veterinary purposes; sanitary products for medical purposes, namely sanitary pads, sanitary towels, sanitary napkins; dietetic substances for medical use, namely, dietetic foods adapted for medical purposes, food for babies; medical plasters; materials for dressings namely, wound dressings, sterilized dressing; burn dressings; teeth filling materials; dental impression materials; disinfectants; preparations for destroying vermin; fungicides; herbicides; remedies for human medicine in the nature of natural remedy preparations for the treatment of gastrointestinal conditions, hormonal and chemical imbalances, and sleep disorders; antibiotics; antiseptics; chemico-pharmaceutical products, namely, chemical preparations for pharmaceutical or medical purposes, namely for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; pharmaceutical healthcare preparations, namely, pharmaceutical products for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; radiological contrast substances for medical use; chemical reagents for medical use; bacteriological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; biological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; enzyme preparations for medical purpose; chemical preparations for medical or pharmaceutical purposes, namely, chemical preparations for pharmaceutical or medical purposes, namely for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; diagnostic testing products for medical use in the form of medical diagnostic reagents and assays for use in disease testing; drugs for medical use namely, nanomaterial-based pharmaceutical preparation of active ingredients for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicines for human consumption for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicated tonics for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; bath preparations for medical use Scientific research instruments, namely, medical laboratory research instruments for DNA analysis; data processing equipment, namely, data processors; computers; Laboratory chemical reactors; downloadable computer programs for provision of information relating to medicine, health and well-being; pre-recorded compact discs in the fields of nanotechnology and biotechnology; digital recording media, namely, pre-recorded video cassettes, digital video discs, digital versatile discs, downloadable audio and video recordings, DVDs, and high definition digital discs in the fields of nanotechnology and biotechnology; computer peripheral devices; apparatus for recording, transmission or reproduction of sound or images; equipment, apparatus and articles for infants, namely, computer hardware and non-downloadable computer software for improving communication with children with disabilities and for operating devices for visualizing or improving sign language translation via machine-child communication Surgical apparatus and instruments namely cryoprobes for treatment and removal of tumors, lasers for surgical and medical use; medical apparatus and instruments for the diagnosis and treatment of tumors, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor; orthopedic articles and mobility articles, namely devices for improving immobility related to cognitive disorders or immobility related to CNS disabilities, such as cross-section paralysis; massage apparatus; prostheses, namely, prosthetic tissues for parietal, visceral and vascular use; artificial implants and prostheses, namely artificial prosthetic tissues for parietal, visceral and vascular use; therapeutic and assistance apparatus for handicapped persons, namely, invalid hoists and invalid walkers; physical therapy equipment, namely weight lifting machines for physical therapy; equipment, apparatus and articles for infants, namely hearing devices for improving communication with children with disabilities; radiotherapy apparatus; immunochemical testing apparatus for medical use; diagnostic apparatus for medical use; radiology screens for medical use; X-ray photographs for medical use; radiological apparatus for medical use; receptacles for applying medicines namely, medical fluid injectors; furniture especially made for medical purposes; surgical and medical apparatus and instruments, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor Education services, namely, conducting programs, classes and seminars in the fields of biotechnology and nanotechnology; Medical training for medical professionals in the fields of biotechnology and nanotechnology; organising sporting and cultural activities, namely, festivals for entertainment purposes; entertainment information; Providing information relating to educational services; publication of books; videotape editing; photography services; organization of sport competitions; organization of educational competitions in the fields of biotechnology and nanotechnology; organizing and conducting of educational colloquiums; organization and conducting of educational conferences; organizing and conducting of educational congresses; organization of exhibitions for cultural or educational purposes; providing online publication of books and journals; electronic desktop publishing; production of cinematographic films, radio and television programs; production of television programs and films on the Internet; organization and conducting of award ceremonies, concerts, fashion shows, charity galas; organization of sporting events, namely running and swimming events; provision of sports facilities; publication of magazines; Sports and entertainment ticket agency services; booking of seats for shows Scientific and technological services, namely, research and design services in the field of nanomedicine in the nature of nanotechnology applied to medicine; biological research services; bacteriological research services; testing, analysis and evaluation of service providers to determine conformity with established accreditation standards, namely, evaluations, estimates and research in scientific and technological fields provided by engineers, researchers; design, research and development of new products for third parties; technical project studies, namely, technical research in the field of pharmaceutical preparations; industrial analysis and research services in the field of biomedical science; chemical analysis; chemical research; chemistry services, namely, chemistry consultation; surveying, namely, conducting engineering surveys; technical research in the field of pharmaceutical industry; radiobiology research; research in nanoscience and nanotechnology, applied to medicine; scientific research; computer software installation; computer software maintenance; updating of computer software; software as a service (SaaS) featuring software for provision of information relating to medicine, health and well-being and featuring software for software for improving communication with children with disabilities and for operating devices for visualizing or improving sign language translation via machine-child communication; design and development of computers and software in the fields of biotechnology and nanotechnology; information technology (IT) consultancy services; scientific and technological services, namely, research and design services in the field of nanomedicine Healthcare in the field of nanomedicine; hospital services; medical assistance; physiotherapy; veterinary services; information services in the medical field, namely, provision of information to health professionals and patients relating to health; medical services for the treatment of gastrointestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medical information services; nursing homes services; physical rehabilitation clinic services; rest home services; opticians' services; alternative medicine services; beauty salon services; hairdressing salon services; services of a psychologist; hygienic and beauty care for human beings or animals; pharmaceutical consultation; Consulting services in the field of health; medical, hygienic and beauty care; providing awareness and information in the field of wellness and health; psychological assessments services; medical assistance; beautician services; sauna services, solarium services
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Broadcasting of cinematographic films, of radio and television programs; broadcasting of television programs, films and other audio and video programs on the Internet Pharmaceutical products for intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases, medical products for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medical products, namely products and preparations for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases and veterinary diagnostic preparations; sanitary products for medical purposes, namely sanitary pads, sanitary towels, sanitary napkins; dietetic substances for medical use, namely, dietetic foods adapted for medical purposes; food for babies; plasters, namely medical plater; materials for dressings, namely wound dressings; teeth filling materials; dental impression materials; disinfectants; preparations for destroying vermin; fungicides; herbicides; remedies for human medicine in the nature of natural remedy preparations for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, and sleep disorders; antibiotics; antiseptics; chemico-pharmaceutical products for pharmaceutical or medical purposes, namely for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; pharmaceutical healthcare preparations for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; radiological contrast substances for medical use; chemical reagents for medical use; bacteriological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; biological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; enzyme preparations for medical purpose; chemical preparations for medical or pharmaceutical purpose, namely for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; diagnostic testing products for medical use in the form of reagents and assays for measuring cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; drugs for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicines for human consumption for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicated tonics for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicated tonics for the improvement of immune defences; bath preparations for medical use Scientific research instruments, namely, medical laboratory research instruments for DNA analysis; data processing equipment, namely, data processors; computers; laboratory chemical reactors (laboratory instruments); downloadable computer programs for provision of information relating to medicine, health and well-being; pre-recorded compact discs in the fields of nanotechnology and biotechnology (CDs); DVD in the fields of nanotechnology and biotechnology; digital recording media, namely, pre-recorded video cassettes, digital video discs, digital versatile discs, downloadable audio and video recordings, DVDs, and high definition digital discs in the field of nanotechnologies and biotechnologies; computer peripheral devices; apparatus for recording, transmission or reproduction of sound or images; equipment, apparatus and articles for infants, namely computer hardware and software for improving communication with children with disabilities such as devices for visualizing or improving sign language translation via machine-child communication Surgical apparatus and instruments for medical or veterinary use; medical apparatus and instruments for the diagnosis and treatment of human diseases such as cancer, CNS-disorders, orthopedics and gastro-intestinal disorders, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor; orthopedic articles and mobility articles, namely devices for improving immobility related to cognitive disorders or immobility related to CNS disabilities, such as cross-section paralysis; massage apparatus; prostheses, namely, prosthetic tissues for parietal, visceral and vascular use; artificial implants and prostheses, namely, artificial prosthetic tissues for parietal, visceral and vascular use; therapeutic and assistance apparatus for handicapped persons, namely, invalid hoists and invalid walkers; physical therapy equipment, namely weight lifting machines for physical therapy; equipment, apparatus and articles for infants, namely hearing devices for improving communication with children with disabilities; radiotherapy apparatus; immunochemical testing apparatus for medical use; diagnostic apparatus for medical use; radiology screens for medical use; X-ray photographs for medical use; radiological apparatus for medical use; receptacles for applying medicines, namely, medical fluid injectors; especially made furniture for medical use; surgical and medical apparatus and instruments, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor Education services, namely, conducting programs in the fields of biotechnology and nanotechnology; Training in the fields of biotechnology and nanotechnology; organising sporting and cultural activities, namely, festivals for entertainment purposes; entertainment information; information relating to educational services; publication of books; videotape editing; photography services; organization of sport competitions; organization of educational competitions in the fields of biotechnology and nanotechnology; organizing and conducting of educational colloquiums; organizing and conducting of educational conferences; organizing and conducting of educational congresses; organization of exhibitions for cultural or educational purposes; providing online publication of books and journals online; electronic desktop publishing; production of cinematographic films, of radio and television programs; production of television programs and films on the Internet; organization and conducting of incentive award ceremonies, concerts, fashion shows, charity galas; organization of sporting events, all for others; provision of sports facilities; publication of magazines; ticket agency services; booking of seats for shows Scientific and technological services namely, research and design services in the field of biotechnologies science for humans, nanomedicine in the nature of nanotechnology applied to medicine; biological research services; bacteriological research services; testing, analysis and evaluation of service providers to determine conformity with established accreditation standards, namely, evaluations, estimates and research in scientific and technological fields provided by engineers, researchers; design, research and development of new products for third parties; technical project studies, namely, technical research in the field of pharmaceutical project studies; industrial analysis and research services in the field of biomedical research; chemical analysis; chemical research; chemistry services, namely, chemistry consultation; surveying, namely, conducting engineering surveys; technical research in the field of pharmaceutical studies; radiobiology research; research in nanoscience and nanotechnology, especially applied to medicine; scientific research; computer software installation; computer software maintenance; updating of computer software; software as a service (SaaS) featuring software for the provision of information relating to medicine, health and well-being and featuring software for software for improving communication with children with disabilities and for operating devices for visualizing or improving sign language translation via machine-child communication; design and development of computers and software for the provision of information relating to medicine, health and well-being and featuring software for software for improving communication with children with disabilities and for operating devices for visualizing or improving sign language translation via machine-child communication; information technology (IT) consultancy services; scientific and technological services as well as namely, research and design services particularly in the field of nanomedicine Healthcare especially in the field of nanomedicine; hospital services; medical assistance; physiotherapy; veterinary services; information services in the medical field, namely, provision of information to health professionals and patients relating to health; medical services namely, diagnostic in the field of nanomedicine; medical information services; nursing homes services; physical rehabilitation clinic services; rest home services; opticians' services; alternative medicine services; beauty salon services; hairdressing salon services; services of a psychologist; hygienic and beauty care for human beings or animals; health consultancy services; medical, hygienic and beauty care; providing awareness and information in the field of wellness and health; psychological assessments services; medical assistance; beautician services; sauna services, solarium services
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Broadcasting of cinematographic films, of radio and television programs; broadcasting of television programs, films and other audio and video programs on the Internet Pharmaceutical products for intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medical products for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases, medical products, namely, preparations for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases and veterinary diagnostic preparations; sanitary products for medical purposes, namely, sanitary pads, sanitary towels, sanitary napkins; dietetic substances for medical use namely, namely, dietetic foods adapted for medical purposes; food for babies; plasters, namely, medical plasters; materials for dressings, namely, wound dressings; teeth filling materials; dental impression materials; disinfectants; preparations for destroying vermin; Fungicides; herbicides; remedies for human medicine in the nature of natural remedy preparations for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, and sleep disorders; antibiotics; antiseptics; chemico-pharmaceutical products for pharmaceutical or medical purposes, namely, for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; pharmaceutical healthcare preparations for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; radiological contrast substances for medical use; chemical reagents for medical use; bacteriological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; biological preparations for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; enzyme preparations for medical purpose; chemical preparations for medical or pharmaceutical purposes, namely, for the treatment of cancer, central nervous system disorder, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; diagnostic testing products for medical use in the form of in the form of reagents and assays for use in disease testing, namely, cancer, central nervous system disorder, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; drugs for medical use for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicines for human consumption for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases; medicated tonics for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases and for the treatment of immune system related diseases and disorders; bath preparations for medical use; products, namely, pharmaceutical products for the diagnosis and treatment of tumors; products, namely, pharmaceutical product and preparations for the treatment of cancer, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases for medical use scientific research instruments, namely, medical laboratory research instruments for DNA analysis; data processing equipment, namely, data processors; computers; laboratory chemical reactors; downloadable computer programs for provision of information relating to medicine, health and well-being; pre-recorded compact discs for the provision of information relating to nanotechnology and biotechnology; DVDs featuring information relating to nanotechnology and biotechnology; digital recording media, namely, pre-recorded video cassettes, digital video discs, digital versatile discs, downloadable audio and video recordings, DVDs, and high definition digital discs featuring information relating to nanotechnology and biotechnology; computer peripheral devices; apparatus for recording, transmission or reproduction of sound or images; equipment, apparatus and articles for infants, namely, computer hardware and downloadable software for augmentative and alternative communication for use in connection with enabling functional communication and therapy for children with disabilities Surgical apparatus and instruments for use in general medical or veterinary surgery; medical apparatus and instruments, namely, apparatus use for the diagnosis and treatment of human cancer, CNS-disorders, orthopedic disorders and gastro-intestinal disorders, namely, surgical apparatus and instruments for use in oncologic surgery, lasers for surgical and medical use, medical imaging devices, namely, ultrasound imaging apparatus, scanners and needle guides, and parts and fittings therefor; orthopedic articles and mobility articles, namely, devices for increasing or improving mobility of persons whose mobility is impaired because of cognitive disorders and CNS disabilities, namely, manual and powered wheelchair; massage apparatus; surgical implants comprised primarily of artificial material for surgical implantation for parietal, visceral and vascular stabilization and healing; implants consisting of artificial materials for surgical implants or parietal, visceral and vascular stabilization and healing; therapeutic and assistance apparatus for handicapped persons, namely, invalid hoists and invalid walkers; physical therapy equipment, namely, weight lifting machines for physical therapy; equipment, apparatus and articles for infants, namely, hearing devices for improving communication with children with disabilities; radiotherapy apparatus; immunochemical testing apparatus for medical use; diagnostic apparatus for medical use; radiology screens for medical use; X-ray photographs for medical use; radiological apparatus for medical use; receptacles for applying medicines namely, medical fluid injectors; especially made furniture for medical use Education services, namely, conducting programs in the field of fields of biotechnology and nanotechnology; training in the fields of biotechnology and nanotechnology; organizing sporting and cultural activities, namely, festivals for entertainment purposes; entertainment information; Information relating to educational services; publication of books; videotape editing; photography services; organization of sports competitions; organization of educational competitions in the fields of biotechnology and nanotechnology; organizing and conducting of educational colloquiums; organizing and conducting of educational conferences; organizing and conducting of educational congresses; organization of exhibitions for cultural or educational purposes; providing online publication of books and journals; electronic desktop publishing; production of cinematographic films, of radio and television programs; production of educational television programs, educational films and educational audio and video programs on the Internet; organization and conducting of award ceremonies, concerts, fashion shows, charity galas; organization of sporting events; provision of sports facilities; publication of magazines; ticket agency services; booking of seats for shows Scientific and technological services, namely, research and design services in the field of biotechnologies science for humans, nanomedicine in the nature of nanotechnology applied to medicine; biological research services; bacteriological research services; testing, analysis and evaluation of service providers to determine conformity with established accreditation standards, namely, evaluations, estimates and research in scientific and technological fields provided by engineers, researchers; design, research and development of new products for third parties; technical project studies, namely, technical research in the field of pharmaceutical development; analysis and research services in the field of biomedical research; chemical analysis; chemical research; chemistry services, namely, chemistry consultation; surveying, namely, conducting engineering surveys; technical research in the field of pharmaceutical products; radiobiology research; research in nanoscience and nanotechnology, especially applied to medicine; scientific research; technical research in the field of pharmaceutical products; computer software installation; computer software maintenance; updating of computer software; software as a service (SaaS) featuring software for the provision of information relating to intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases, health and well-being and featuring software for augmentative and alternative communication with children with disabilities via high-tech speech generating devices and for operating devices for visualizing and improving sign language translation via machine-child communication; design and development of computers and software for the provision of information relating to medicine, health and well-being and software for improving communication with children with disabilities and for operating devices for visualizing or improving sign language translation via machine-child communication; information technology (IT) consultancy services; scientific and technological services, namely, research and design services particularly in the field of nanomedicine Healthcare especially in the field of nanomedicine; hospital services; medical assistance; physiotherapy; veterinary services; Information services in the medical field, namely, provision of information to health professionals and patients relating to health; Medical services, namely diagnostic services in the field of nanomedicine; Medical information services; Nursing home services; Physical rehabilitation clinic services; rest home services; opticians' services; alternative medicine services; beauty salon services; Hairdressing salon services; Services of a psychologist; Hygienic and beauty care for human beings or animals; Pharmacy consulting services to health care providers in the field of treating intestinal conditions, hormonal and chemical imbalances, sleep disorders, cancers, central nervous system disorders, cardiovascular, immunological, gastrointestinal, metabolic and infectious diseases and health consultancy services; medical, hygienic and beauty care; Providing awareness and information in the field of wellness and health; Psychological assessments services; Medical assistance; Beautician services; sauna services, solarium services
58.
NANOPARTICLES FOR USE FOR TREATING A NEURONAL DISORDER
The present invention relates to the medical field, in particular to the treatment of neurological disorders. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use in prevention or treatment of a neurological disease or at least one symptom thereof in a subject when the nanoparticle or nanoparticles' aggregate is exposed to an electric field, wherein the nanoparticle's or nanoparticles' aggregate's material is selected from a conductor material, a semiconductor material, an insulator material with a dielectric constant (εijk) equal to or above 200, and an insulator material with a dielectric constant (εijk) equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
The present invention relates to the medical field, in particular to the modulation of electrical polarization of neurons. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use for modulating electrical polarization of neurons in a subject, for example for use in prevention or treatment of a neuronal disease in a subject, typically by modulating electrical polarization of neurons in the subject, wherein i) when the nanoparticle or nanoparticles' aggregate is exposed to a light source, the nanoparticle's or nanoparticles' aggregate's material is selected from a material enabling opto-electric transduction, opto-thermal transduction or opto-optical transduction, ii) when the nanoparticle or nanoparticles' aggregate is exposed to a magnetic field, the nanoparticle's or nanoparticles' aggregate's material is selected from a material enabling magneto-electric transduction or magneto-thermal transduction, iii) when the nanoparticle or nanoparticles' aggregate's surface is exposed to an ultrasound source, the nanoparticle's or nanoparticles' aggregate's material is a material enabling acousto-electric transduction, and wherein the nanoparticle or nanoparticles' aggregate is either neutrally charged in the absence of any coating or is coated with a hydrophilic agent conferring a neutral surface charge to the nanoparticle or nanoparticles' aggregate. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
The present invention relates to the medical field, in particular to the treatment of neurological disorders. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use in prevention or treatment of a neurological disease or at least one symptom thereof in a subject when the nanoparticle or nanoparticles' aggregate is exposed to an electric field, wherein the nanoparticle's or nanoparticles' aggregate's material is selected from a conductor material, a semiconductor material, an insulator material with a dielectric constant (eijk) equal to or above 200, and an insulator material with a dielectric constant (eijk) equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
The present invention relates to the medical field, in particular to the enhancement of brain performances and to the treatment of pathological stress. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use in enhancing brain performances or in prevention or treatment of pathological stress in a subject when the nanoparticle and/or nanoparticles' aggregate is exposed to an electric field, wherein the nanoparticle's or nanoparticles' aggregate's material is selected from a conductor material, a semiconductor material, an insulator material with a dielectric constant ɛijk equal to or above 200, and an insulator material with a dielectric constant ɛijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
The present invention relates to the field of human health and more particularly concerns nanoparticles for use as a therapeutic vaccine in the context of radiotherapy in a subject suffering of a cancer, in particular of a metastatic cancer or of a liquid cancer.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products, namely agents for tumor treatment
for use only in relation to radiotherapy; medicines for
human use for use only in relation to radiotherapy for
cancer treatment; healthcare products, namely
pharmaceutical products for cancer treatment for use only in
relation to radiotherapy; drugs for medical use for cancer
treatment for use only in relation to radiotherapy;
preparations for medical use for use only in relation to
radiotherapy, particularly for tumor treatment; radiological
contrast substances for medical use; chemical reagents for
medical use for use only in relation to radiotherapy for
cancer treatment; medical preparations for medical or
pharmaceutical use consisting of medication delivery agents
in the form of tablets and capsules for cancer treatment for
use only in relation to radiotherapy;
chemical-pharmaceutical products consisting in tablets or
injectable products for cancer treatment for use only in
relation to radiotherapy; diagnostic biomarking reagents for
medical use for use only in relation to radiotherapy. Diagnostic apparatus for medical use, namely X-ray apparatus
for medical use; radiology screens for medical use.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products, namely agents for tumor treatment
for use only in relation to radiotherapy; medicines for
human use for use only in relation to radiotherapy for
cancer treatment; healthcare products, namely
pharmaceutical products for cancer treatment for use only in
relation to radiotherapy; drugs for medical use for cancer
treatment for use only in relation to radiotherapy;
preparations for medical use for use only in relation to
radiotherapy, particularly for tumor treatment; radiological
contrast substances for medical use; chemical reagents for
medical use for use only in relation to radiotherapy for
cancer treatment; medical preparations for medical or
pharmaceutical use consisting of medication delivery agents
in the form of tablets and capsules for cancer treatment for
use only in relation to radiotherapy;
chemical-pharmaceutical products consisting in tablets or
injectable products for cancer treatment for use only in
relation to radiotherapy; diagnostic biomarking reagents for
medical use for use only in relation to radiotherapy. Diagnostic apparatus for medical use, namely X-ray apparatus
for medical use; radiology screens for medical use.
65.
Metallic nanoparticles, preparation and uses thereof
The present application relates to activatable nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cells, tissues or organs. It more particularly relates to nanoparticles which can generate a significantly efficient therapeutic effect, when exposed to ionizing radiations. The inventive nanoparticle is a metallic nanoparticle having, as the largest size, a size comprised between about 80 and 105 nm, the metal having preferably an atomic number (Z) of at least 25. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.
The present invention relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle and (ii) at least one carrier comprising at least one pharmaceutical compound, to be administered to a subject in need of such a pharmaceutical compound, wherein the combination of the at least one biocompatible nanoparticle and of the at least one carrier comprising the pharmaceutical compound(s) potentiates the compound(s) of interest effectiveness in therapy, prophylaxis or diagnosis. The invention also relates to such a composition for use for administering the pharmaceutical compound(s) in a subject in need thereof, wherein the at least one biocompatible nanoparticle and the at least one carrier comprising the at least one pharmaceutical compound are to be administered separately in a subject in need of said pharmaceutical compound, typically between more than 5 minutes and about 72 hours one from each other.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
67.
Pharmaceutical compositions, preparation and uses thereof
The present disclosure generally relates to the field of medicine. The present invention more specifically relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle comprising, or consisting in, at least one natural compound which is an inhibitor of a human CYP enzyme, the longest dimension of said nanoparticle being of at least 4 nm and less than 100 nm, and (ii) at least one compound of interest, typically at least one pharmaceutical compound, to be administered to a subject in need of such at least one compound of interest, wherein the combination of the at least one biocompatible nanoparticle and of the at least one compound of interest potentiates the at least one compound of interest's bioavailability. The at least one biocompatible nanoparticle is to be administered to the subject separately from the at least one compound of interest (preferably before), typically with an interval of between at least about 5 minutes (preferably more than about 5 minutes) and about 72 hours.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
The present invention relates to a pharmaceutical composition comprising the combination of (i) at least two distinct biocompatible nanoparticles and (ii) at least one compound of interest, typically at least one pharmaceutical compound, to be administered to a subject in need of such at least one compound of interest, wherein the at least two distinct biocompatible nanoparticles potentiate the compound(s) of interest efficiency. The at least two biocompatible nanoparticles can be administered sequentially or simultaneously to the subject but are to be administered separately, typically with an interval of between more than about 5 minutes and about 72 hours, from the at least one compound of interest, preferably before the administration of the at least one compound of interest, to said subject. The longest dimension of the at least two biocompatible nanoparticles is typically between about 4 nm and about 500 nm. The absolute surface charge value of a first biocompatible nanoparticle is of at least |10 mV| and the absolute surface charge value of the second biocompatible nanoparticle, or of any additional biocompatible nanoparticle, has a difference of at least 10 mV with the absolute surface charge value of the first biocompatible nanoparticle.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products, namely, agents for tumor treatment for use only in relation to radiotherapy; medicines for human use for use only in relation to radiotherapy for cancer treatment; healthcare products, namely, pharmaceutical products for cancer treatment for use only in relation to radiotherapy; drugs for medical use for cancer treatment for use only in relation to radiotherapy; preparations for medical use for use only in relation to radiotherapy, particularly for tumor treatment; radiological contrast substances for medical use; chemical reagents for medical use for use only in relation to radiotherapy for cancer treatment; medical preparations for medical or pharmaceutical use consisting of medication delivery agents in the form of tablets and capsules for cancer treatment for use only in relation to radiotherapy; chemical-pharmaceutical products consisting in tablets or injectable products for cancer treatment for use only in relation to radiotherapy; diagnostic biomarking reagents for medical use for use only in relation to radiotherapy Diagnostic apparatus for medical use, namely, X-ray apparatus for medical use; radiology screens for medical use
The present invention relates to the field of human health and more particularly concerns nanoparticles for use as a therapeutic vaccine in the context of radiotherapy in a subject suffering of a cancer, in particular of a metastatic cancer or of a liquid cancer.
The present invention relates to the field of human health and more particularly concerns nanoparticles for use as a therapeutic vaccine in the context of radiotherapy in a subject suffering of a cancer, in particular of a metastatic cancer or of a liquid cancer.
The present application relates to a pharmaceutical composition comprising biocompatible nanoparticles or nanoparticles aggregates which allows the appropriate delivery of said biocompatible nanoparticles or nanoparticles aggregates to a target site in a subject in need thereof. The composition indeed allows an accumulation of the biocompatible nanoparticles or nanoparticles aggregates it comprises into the targeted tissue of the subject of at least 4 milligram (mg) nanoparticles or nanoparticles aggregates per gram (g) of targeted tissue when at least 0.1 g of the pharmaceutical composition per kilogram (kg) of body weight is injected intravenously (IV) or intraarterially (IA) into said subject.
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61K 47/60 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p. ex. une molécule oligomérique, polymérique ou dendrimérique obtenu par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyurées ou polyuréthanes le composé organique macromoléculaire étant un oligomère, un polymère ou un dendrimère de polyoxyalkylène, p. ex. PEG, PPG, PEO ou polyglycérol
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products for use only in relation to
radiotherapy; medicines for human medicine for use only in
relation to radiotherapy; health products for use only in
relation to radiotherapy, namely pharmaceutical products for
use only in relation to radiotherapy for cancer treatment;
preparations for medical use for use only in relation to
radiotherapy, particularly for tumor treatment; radiological
contrast substances for medical use; medical reagents for
medical use for use only in relation to radiotherapy;
chemical preparations for medical or pharmaceutical use for
use only in relation to radiotherapy; drugs for medical use
for use only in relation to radiotherapy;
chemical-pharmaceutical products for use only in relation to
radiotherapy; diagnostic biomarking reagents for medical
use for use only in relation to radiotherapy. Testing apparatus for medical use; diagnostic apparatus for
medical use; apparatus for medical use; screens for medical
use.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Business information; business investigations. Education; training services; organization and conducting
of conferences; organization and conducting of congresses;
organization and conducting of seminars; organization and
production of shows; presentation of live performances;
publication of magazines, books and manuals in the field of
medicine; conducting of training courses in the field of
technology and innovation. Scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine);
evaluations, assessments and research in the field of
nanoscience and nanotechnology, particularly applied to
medicine; preparation of reports relating to research in
nanoscience and nanotechnology; provision of information
(information services) regarding medical technology.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products; medicines for human medicine;
health products, namely pharmaceutical products for cancer
treatment; preparations for medical use, particularly for
tumor treatment; radiological contrast substances for
medical use; chemical reagents for medical use; chemical
preparations for medical or pharmaceutical use; drugs for
medical use; chemico-pharmaceutical products; diagnostic
biomarking reagents for medical use. Testing apparatus for medical use; diagnostic apparatus for
medical use; apparatus for medical use; screens for medical
use.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Business information; business investigations. Education; training services; organization and conducting
of conferences; organization and conducting of congresses;
organization and conducting of seminars; organization and
production of shows; presentation of live performances;
publication of magazines, books and manuals in the field of
medicine; conducting of training courses in the field of
technology and innovation. Scientific and technological services as well as research
and design services particularly in the field of
nanomedicine (nanotechnology applied to medicine);
evaluations, assessments and research in the field of
nanoscience and nanotechnology, particularly applied to
medicine; preparation of reports relating to research in
nanoscience and nanotechnology; provision of information
(information services) regarding medical technology.
77.
Pharmaceutical composition, preparation and uses thereof
The present invention relates to a pharmaceutical composition comprising the combination of (i) a biocompatible nanoparticle and of (ii) a pharmaceutical compound of interest, to be administered to a subject in need of such a compound of interest, wherein the nanoparticle potentiates the compound of interest efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm, and its absolute surface charge value is of at least 10 mV (|10 mV|). The invention also relates to such a composition for use for administering the compound of interest to a subject in need thereof, wherein the nanoparticle and the compound of interest are to be administered to said subject between more than 5 minutes and about 72 hours from each other.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
78.
PHARMACEUTICAL COMPOSITION, PREPARATION AND USES THEREOF
The present invention relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle and of (ii) at least one carrier comprising at least one pharmaceutical compound, to be administered to a subject in need of such a pharmaceutical compound, wherein the combination of the at least one biocompatible nanoparticle and of the at least one carrier comprising the pharmaceutical compound(s) potentiates the compound(s)of interest efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm and its absolute surface charge value is of at least 10 mV(|10 m V|). The carrier is in addition devoid of any surface sterically stabilizing agent. The invention also relates to such a composition for use for administering the pharmaceutical compound(s) in a subject in need thereof, wherein the at least one biocompatible nanoparticle and the at least one carrier comprising the at least one pharmaceutical compound are to be administered separately in a subject in need of said pharmaceutical compound, typically between more than 5 minutes and about 72 hours one from each other.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes
79.
PHARMACEUTICAL COMPOSITION, PREPARATION AND USES THEREOF
The present invention relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle and of (ii) at least one carrier comprising at least one pharmaceutical compound, to be administered to a subject in need of such a pharmaceutical compound, wherein the combination of the at least one biocompatible nanoparticle and of the at least one carrier comprising the pharmaceutical compound(s) potentiates the compound(s)of interest efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm and its absolute surface charge value is of at least 10 mV(|10 m V|). The carrier is in addition devoid of any surface sterically stabilizing agent. The invention also relates to such a composition for use for administering the pharmaceutical compound(s) in a subject in need thereof, wherein the at least one biocompatible nanoparticle and the at least one carrier comprising the at least one pharmaceutical compound are to be administered separately in a subject in need of said pharmaceutical compound, typically between more than 5 minutes and about 72 hours one from each other.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes
80.
PHARMACEUTICAL COMPOSITION, PREPARATION AND USES THEREOF
The present invention relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle and of (ii) at least one pharmaceutical compound, to be administered to a subject in need of such a pharmaceutical compound, wherein the nanoparticle potentiates the pharmaceutical compound efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm, its absolute surface charge value is of at least 10 mV (|10 mV|), and its Young modulus is less than 100 kPa. The invention also relates to such a composition for use for administering the pharmaceutical compound in a subject in need thereof, wherein the at least one nanoparticle and the at least one pharmaceutical compound are to be administered in the subject between more than 5 minutes and about 72 hours one from each other.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
81.
PHARMACEUTICAL COMPOSITIONS, PREPARATION AND USES THEREOF
The present disclosure generally relates to the field of medicine. The present invention more specifically relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle comprising, or consisting in, at least one natural compound which is an inhibitor of a human CYP enzyme, the longest dimension of said nanoparticle being of at least 4 nm and less than 100 nm, and of (ii) at least one compound of interest, typically at least one pharmaceutical compound, to be administered to a subject in need of such at least one compound of interest, wherein the combination of the at least one biocompatible nanoparticle and of the at least one compound of interest potentiates the at least one compound of interest's bioavailability. The at least one biocompatible nanoparticle is to be administered to the subject separately from the at least one compound of interest (preferably before), typically with an interval of between at least about 5 minutes (preferably more than about 5 minutes) and about 72 hours.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
The present invention relates to a pharmaceutical composition comprising the combination of (i) at least two distinct biocompatible nanoparticles and (ii) at least one compound of interest, typically at least one pharmaceutical compound,to be administered to a subject in need of such at least one compound of interest, wherein the at least two distinct biocompatible nanoparticles potentiate the compound(s) of interest efficiency. The at least two biocompatible nanoparticles can be administered sequentially or simultaneously to the subject but are to be administered separately, typically with an interval of between more than about 5 minutes and about 72 hours, from the at least one compound of interest, preferably before the administration of the at least one compound of interest, to said subject. The longest dimension of the at least two biocompatible nanoparticles is typically between about 4 nm and about 500 nm. The absolute surface charge value of a firs tbiocompatible nanoparticle is of at least |10 mV| and the absolute surface charge value of the second biocompatible nanoparticle, or of any additional biocompatible nanoparticle, has a difference of at least 10 mV with the absolute surface charge value of the first biocompatible nanoparticle.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes
83.
PHARMACEUTICAL COMPOSITION, PREPARATION AND USES THEREOF
The invention relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle, said biocompatible nanoparticle comprising at least one oligomer of albumin (n≥2) or consisting in an oligomer of albumin, and of(ii) at least one compound of interest,typically at least one pharmaceutical compound,to be administered to a subject in need of such at least one compound of interest, wherein the at least one nanoparticle potentiates the at least one compound of interest efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm. The invention also relates to such a composition for use for administering the at least one compound of interest in a subject in need thereof, wherein the at least one biocompatible nanoparticle and the at least one compound of interest are to be administered in said subject sequentially, typically between more than 5 minutes and about 72 hours one from each other.
A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
−1 of the gel comprising the nanoparticles and/or nanoparticle aggregates is between about 0.1 Pa·s and about 1000 Pa·s when measured between 20° C. and 37° C. The composition of the invention typically allows the delineation and visualization of at least 40% of the target biological tissue when said tissue is observed using an X-ray imaging equipment.
A61K 47/50 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical products, namely agents for the treatment of tumors in the field of radiation therapy; medicines for humans for the treatment of cancer; health products, namely, pharmaceutical preparations for cancer treatment; preparations for medical use, particularly for tumor treatment; radiological contrast substances for medical use; chemical reagents for medical use; chemical preparations for medical and pharmaceutical use being drug delivery agents in the form of tablets and capsules for the treatment of cancer; drugs for medical use for the treatment of cancer; chemico-pharmaceutical products being tablets for the treatment of cancer; diagnostic biomarking reagents for medical use Testing apparatus for medical use, namely medical X-ray apparatus; diagnostic apparatus for medical use, namely medical X-ray apparatus; apparatus for medical use, namely therapeutic mattresses, beds, seats and cushions; screens for medical use
86.
Method of monitoring the release from liposomes of a product of interest using superparamagnetic nanoparticles
2* before and after the heating step b). A ratio above 1.5 indicates the liposome membrane permeabilization and the incidental release of the product of interest.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 49/18 - Préparations de contraste pour la résonance magnétique nucléaire [RMN]Préparations de contraste pour l'imagerie par résonance magnétique [IRM] caractérisées par un aspect physique particulier, p. ex. émulsions, microcapsules, liposomes
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
G01N 24/08 - Recherche ou analyse des matériaux par l'utilisation de la résonance magnétique nucléaire, de la résonance paramagnétique électronique ou d'autres effets de spin en utilisant la résonance magnétique nucléaire
G01R 33/56 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne
87.
Inorganic nanoparticles compositions in combination with ionizing radiations for treating cancer
The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cancerous cells, tissues or organs. It more particularly relates to nanoparticles which can generate a surprisingly efficient therapeutic effect, when concentrated inside the tumor and exposed to ionizing radiations. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Products for medical use particularly for the treatment of
tumors; products for medical use particularly for treatment
of tumors using radiation therapy; radioactive products for
medical use for treatment of tumors using radiation therapy;
health products namely pharmaceutical products; radiological
contrast substances for medical use; chemical reagents for
medical use; chemical preparations for medical or
pharmaceutical use; drugs for medical use; medicines for
human medicine; chemico-pharmaceutical products;
pharmaceutical products; remedies for human medicine; all
these products for use in clinical studies in the field of
radiation therapy.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Products for medical use particularly for the treatment of
tumors; products for medical use particularly for treatment
of tumors using radiation therapy; radioactive products for
medical use for treatment of tumors using radiation therapy;
health products namely pharmaceutical products; radiological
contrast substances for medical use; chemical reagents for
medical use; chemical preparations for medical or
pharmaceutical use; drugs for medical use; medicines for
human medicine; chemico-pharmaceutical products;
pharmaceutical products; remedies for human medicine; all
these products for use in clinical studies in the field of
radiation therapy.
90.
PHARMACEUTICAL COMPOSITION COMPRISING NANOPARTICLES, PREPARATION AND USES THEREOF
The present application relates to a pharmaceutical composition comprising biocompatible nanoparticles or nanoparticles aggregates which allows the appropriate delivery of said biocompatible nanoparticles or nanoparticles aggregates to a target site in a subject in need thereof. The composition indeed allows an accumulation of the biocompatible nanoparticles or nanoparticles aggregates it comprises into the targeted tissue of the subject of at least 4 milligram (mg) nanoparticles or nanoparticles aggregates per gram (g) of targeted tissue when at least 0.1 g of the pharmaceutical composition per kilogram (kg) of body weight is injected intravenously (IV) or intraarterially (IA) into said subject.
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
91.
COMPOSITIONS AND METHODS FOR USE IN MEDICAL DIAGNOSIS
The present invention relates to compositions and methods for use in medical diagnosis and patient's monitoring. It more particularly relates to a biocompatible gel comprising nanoparticles and/or nanoparticles aggregates, wherein i) the nanoparticle and/or nanoparticles aggregate comprise an inorganic material comprising at least one metal element having an atomic number Z of at least 25, each of said nanoparticle and of said nanoparticles aggregate being covered with a biocompatible coating; ii) the nanoparticles and/or nanoparticles aggregates concentration is of about or less than 0.5% (w/w); and iii) the apparent viscosity at 2s - of the gel comprising nanoparticles and/or nanoparticles aggregates, is between about 0.1 Pa.s and about 1000 Pa.s when measured between 20°C and 37°C. 1 The composition of the invention typically allows the delineation and visualization of at least 40% of the target biological tissue when said tissue is observed using an X-ray imaging equipment.
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
The present invention relates to compositions and methods for use in medical diagnostic and patient monitoring, typically in the context of therapy, in particular in the context of oncology to optimize tumor bed local irradiation. It more particularly relates to a biocompatible gel comprising nanoparticles and/or nanoparticles aggregates, wherein i) the density of each nanoparticle and of each nanoparticles aggregate is of at least 7 g/cm3, the nanoparticle or nanoparticles aggregate comprising an inorganic material comprising at least one metal element having an atomic number Z of at least 25, more preferably of at least 40, each of said nanoparticle and of said nanoparticles aggregate being covered with a biocompatible coating; ii) the nanoparticles and/or nanoparticles aggregates concentration is of at least about 1% (w/w); and iii) the apparent viscosity at 2 s-1 of the gel comprising nanoparticles and/or nanoparticles aggregates, is between about 0.1 Pa.s and about 1000 Pa.s when measured between 20°C and 37°C.
The present invention relates to compositions and methods for use in medical diagnostic and patient monitoring, typically in the context of therapy, in particular in the context of oncology to optimize tumor bed local irradiation. It more particularly relates to a biocompatible gel comprising nanoparticles and/or nanoparticles aggregates, wherein i) the density of each nanoparticle and of each nanoparticles aggregate is of at least 7 g/cm3, the nanoparticle or nanoparticles aggregate comprising an inorganic material comprising at least one metal element having an atomic number Z of at least 25, more preferably of at least 40, each of said nanoparticle and of said nanoparticles aggregate being covered with a biocompatible coating; ii) the nanoparticles and/or nanoparticles aggregates concentration is of at least about 1% (w/w); and iii) the apparent viscosity at 2 s-1 of the gel comprising nanoparticles and/or nanoparticles aggregates, is between about 0.1 Pa.s and about 1000 Pa.s when measured between 20°C and 37°C.
The present invention relates to a pharmaceutical composition comprising the combination of (i) a biocompatible nanoparticle and of (ii) a pharmaceutical compound of interest, to be administered to a subject in need of such a compound of interest, wherein the nanoparticle potentiates the compound of interest efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm, and its absolute surface charge value is of at least 10 m V (|10 m V|). The invention also relates to such a composition for use for administering the compound of interest in a subject in need thereof, wherein the nanoparticle and the compound of interest are to be administered in said subject between more than 5 minutes and about 72 hours one from each other.
The present invention relates to a pharmaceutical composition comprising the combination of (i) a biocompatible nanoparticle and of (ii) a pharmaceutical compound of interest, to be administered to a subject in need of such a compound of interest, wherein the nanoparticle potentiates the compound of interest efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm, and its absolute surface charge value is of at least 10 m V (|10 m V|). The invention also relates to such a composition for use for administering the compound of interest in a subject in need thereof, wherein the nanoparticle and the compound of interest are to be administered in said subject between more than 5 minutes and about 72 hours one from each other.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
96.
Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof
The present invention relates to novel nanoparticles which can be advantageously used in the health sector as diagnostic and/or therapeutic agents. Nanoparticles of the invention comprise a metallic material at least partly covered with a hafnium oxide material or embedded therein. When compared to existing products, these nanoparticles offer a remarkable benefit over risk ratio. Specifically, these nanoparticles potentiate the efficiency of known metallic nanoparticles. Indeed, they retain the metal's intrinsic properties and are now in addition safely usable in a mammal, in particular in a human being. The invention also relates to methods for producing said nanoparticles, to compositions containing same, and to uses thereof.
A61K 49/04 - Préparations de contraste pour rayons X
A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cancerous cells, tissues or organs. It more particularly relates to nanoparticles which can generate a surprisingly efficient therapeutic effect, when concentrated inside the tumor and exposed to ionizing radiations. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.
The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cancerous cells, tissues or organs. It more particularly relates to nanoparticles which can generate a surprisingly efficient therapeutic effect, when concentrated inside the tumor and exposed to ionizing radiations. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.
The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cancerous cells, tissues or organs. It more particularly relates to nanoparticles which can generate a surprisingly efficient therapeutic effect, when concentrated inside the tumor and exposed to ionizing radiations. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.
The invention pertains to thermosensitive liposomes encapsulating nanoparticles. In certain embodiments, the thermosensitive liposomes of the invention disrupt when heated at gel-to-liquid crystalline phase transition temperature (Tm) or above Tm, wherein the liposome comprises a thermosensitive lipidic membrane encapsulating nanoparticles. The nanoparticles used in the invention comprise an inorganic core the largest dimension of which is less than about 100 nm that is fully coated with an agent responsible for the presence of an electrostatic charge below −20 mV or above +20 mV at the surface of the nanoparticle, the electrostatic charge being determined by zeta potential measurements in an aqueous medium between pH 6 and 8, for a concentration of nanoparticles in suspension in the aqueous medium varying between 0.2 and 8 g/L. The invention also relates to pharmaceutical and diagnostic compositions comprising the thermosensitive liposomes as well as to their uses.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61K 49/18 - Préparations de contraste pour la résonance magnétique nucléaire [RMN]Préparations de contraste pour l'imagerie par résonance magnétique [IRM] caractérisées par un aspect physique particulier, p. ex. émulsions, microcapsules, liposomes
