Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions. Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions. Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions. Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions. Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions. Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions. Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Downloadable educational course materials in the field of health, diseases and disorders, and pharmaceuticals Educational services, namely, conducting online courses in the field of health, diseases and disorders, and pharmaceuticals and distribution of course material in connection therewith Providing medical information

Produits et services

Downloadable podcasts in the field of health, pharmaceuticals, and medicine; Downloadable podcasts in the field of tardive dyskinesia and other medical conditions Production of podcasts; Providing podcasts in the field of health, pharmaceuticals, and medicine; Providing podcasts in the field of tardive dyskinesia and other medical conditions

Abrégé

The present disclosure relates to pharmaceutical compositions comprising a gonadotropin-releasing hormone (GnRH) antagonist and methods of preparing and using such compositions. The disclosure also relates to methods of facilitating release of a GnRH antagonist from a pharmaceutical composition.

Classes IPC  ?

• A61K 9/20 - Pilules, pastilles ou comprimés
• A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
• A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs

Abrégé

This disclosure provides fatty acid conjugated cyclic peptides, pharmaceutical compositions comprising such fatty acid conjugated cyclic peptides and methods of using such fatty acid conjugated cyclic peptides to treat or prevent diseases associated with the abnormal or dysregulated activity of corticotropin releasing factor (CRT) signaling.

Classes IPC  ?

• A61K 38/00 - Préparations médicinales contenant des peptides
• A61K 38/22 - Hormones
• C07K 14/00 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
• C07K 14/575 - Hormones

Produits et services

Pharmaceutical research and development services; conducting clinical trials for others for pharmaceutical preparations; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results; pharmaceutical research and development services in the field of neurological, central nervous system, and movement diseases and disorders and tardive dyskinesia; conducting clinical trials for others for pharmaceutical preparations for the treatment and prevention of neurological, central nervous system, and movement diseases and disorders and tardive dyskinesia; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials pertaining to therapies and treatments for neurological, central nervous system, and movement diseases and disorders and tardive dyskinesia; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations for the treatment and prevention of neurological, central nervous system, and movement diseases and disorders and tardive dyskinesia, and evaluating epidemiological results for treatments for neurological, central nervous system, and movement diseases and disorders and tardive dyskinesia Providing medical information; providing medical information relating to therapies and treatments for neurological, central nervous system, and movement diseases and disorders and tardive dyskinesia

Produits et services

Promoting awareness of congenital adrenal hyperplasia; promoting awareness of adrenal insufficiency; promoting awareness of endocrine diseases and disorders; promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy; promoting the interests of people who have adrenal insufficiency and their families and health care providers by means of public advocacy; promoting the interests of people who have endocrine diseases and disorders and their families and health care providers by means of public advocacy; maintaining a registry of patients with congenital adrenal hyperplasia; maintaining a registry of patients with adrenal insufficiency; maintaining a registry of patients with endocrine diseases and disorders; updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia; updating and maintenance of information in registries, namely, administering a patient registry for patients with adrenal insufficiency; updating and maintenance of information in registries, namely, administering a patient registry for patients with endocrine diseases and disorders. Providing an in-person health forum for users to participate in discussions in the field of congenital adrenal hyperplasia; providing an in-person health forum for users to participate in discussions in the field of adrenal insufficiency; providing an in-person health forum for users to participate in discussions in the field of endocrine diseases and disorders. Providing information about medical research; providing medical research information in the field of pharmaceuticals and congenital adrenal hyperplasia; providing medical research information in the field of pharmaceuticals and adrenal insufficiency; providing medical research information in the field of pharmaceuticals and endocrine diseases and disorders; providing a public platform to discuss congenital adrenal hyperplasia and coping strategies; providing a public platform to discuss adrenal insufficiency and coping strategies; providing a public platform to discuss endocrine diseases and disorders and coping strategies. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia; providing medical information to patients, medical professionals, and insurance companies in the field of adrenal insufficiency; providing medical information to patients, medical professionals, and insurance companies in the field of endocrine diseases and disorders; online information services, namely, providing medical information in the field of congenital adrenal hyperplasia; online information services, namely, providing medical information in the field of adrenal insufficiency; online information services, namely, providing medical information in the field of endocrine diseases and disorders.

Abrégé

Provided herein are methods for treatment of chorea associated with Huntington disease using a vesicular monoamine transporter isoform 2 (VMAT2) inhibitor. In certain embodiments, the VMAT2 inhibitor is valbenazine or a pharmaceutically acceptable salt thereof.

Classes IPC  ?

• A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier

Produits et services

Downloadable podcasts in the field of health, pharmaceuticals, and medicine; Downloadable podcasts in the field of Huntington’s disease, HD chorea and other medical conditions Production of podcasts; Providing podcasts in the field of health, pharmaceuticals, and medicine; Providing podcasts in the field of Huntington’s disease, HD chorea and other medical conditions

Produits et services

Downloadable podcasts in the field of health, pharmaceuticals, and medicine; Downloadable podcasts in the field of Huntington’s disease, HD chorea and other medical conditions Production of podcasts; Providing podcasts in the field of health, pharmaceuticals, and medicine; Providing podcasts in the field of Huntington’s disease, HD chorea and other medical conditions

Produits et services

Promoting awareness of congenital adrenal hyperplasia and providing a public platform to discuss congenital adrenal hyperplasia and coping strategies (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting awareness of adrenal insufficiency and providing a public platform to discuss adrenal insufficiency and coping strategies (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting awareness of endocrine diseases and disorders and providing a public platform to discuss endocrine diseases and disorders and coping strategies (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting the interests of people who have adrenal insufficiency and their families and health care providers by means of public advocacy (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting the interests of people who have endocrine diseases and disorders and their families and health care providers by means of public advocacy (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); maintaining a registry of patients with congenital adrenal hyperplasia; maintaining a registry of patients with adrenal insufficiency; maintaining a registry of patients with endocrine diseases and disorders; updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia; updating and maintenance of information in registries, namely, administering a patient registry for patients with adrenal insufficiency; updating and maintenance of information in registries, namely, administering a patient registry for patients with endocrine diseases and disorders. Providing an in-person health forum for users to participate in discussions in the field of congenital adrenal hyperplasia; providing an in-person health forum for users to participate in discussions in the field of adrenal insufficiency; providing an in-person health forum for users to participate in discussions in the field of endocrine diseases and disorders. Providing information about medical research; providing medical research information in the field of pharmaceuticals and congenital adrenal hyperplasia; providing medical research information in the field of pharmaceuticals and adrenal insufficiency; providing medical research information in the field of pharmaceuticals and endocrine diseases and disorders. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia; providing medical information to patients, medical professionals, and insurance companies in the field of adrenal insufficiency; providing medical information to patients, medical professionals, and insurance companies in the field of endocrine diseases and disorders; online information services, namely, providing medical information in the field of congenital adrenal hyperplasia; online information services, namely, providing medical information in the field of adrenal insufficiency; online information services, namely, providing medical information in the field of endocrine diseases and disorders.

Produits et services

Promoting awareness of congenital adrenal hyperplasia and providing a public platform to discuss congenital adrenal hyperplasia and coping strategies (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting awareness of adrenal insufficiency and providing a public platform to discuss adrenal insufficiency and coping strategies (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting awareness of endocrine diseases and disorders and providing a public platform to discuss endocrine diseases and disorders and coping strategies (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting the interests of people who have adrenal insufficiency and their families and health care providers by means of public advocacy (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); promoting the interests of people who have endocrine diseases and disorders and their families and health care providers by means of public advocacy (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); maintaining a registry of patients with congenital adrenal hyperplasia; maintaining a registry of patients with adrenal insufficiency; maintaining a registry of patients with endocrine diseases and disorders; updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia; updating and maintenance of information in registries, namely, administering a patient registry for patients with adrenal insufficiency; updating and maintenance of information in registries, namely, administering a patient registry for patients with endocrine diseases and disorders. Providing an in-person health forum for users to participate in discussions in the field of congenital adrenal hyperplasia; providing an in-person health forum for users to participate in discussions in the field of adrenal insufficiency; providing an in-person health forum for users to participate in discussions in the field of endocrine diseases and disorders. Providing information about medical research; providing medical research information in the field of pharmaceuticals and congenital adrenal hyperplasia; providing medical research information in the field of pharmaceuticals and adrenal insufficiency; providing medical research information in the field of pharmaceuticals and endocrine diseases and disorders. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia; providing medical information to patients, medical professionals, and insurance companies in the field of adrenal insufficiency; providing medical information to patients, medical professionals, and insurance companies in the field of endocrine diseases and disorders; online information services, namely, providing medical information in the field of congenital adrenal hyperplasia; online information services, namely, providing medical information in the field of adrenal insufficiency; online information services, namely, providing medical information in the field of endocrine diseases and disorders.

Produits et services

Pharmaceutical research and development services; conducting research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information; providing research information to others as to the results of research studies

Abrégé

The present invention relates to compounds of Formula (Ia), pharmaceutically acceptable salts of compounds of Formula (Ia), and pharmaceutical compositions thereof that modulate the activity of the muscarinic acetylcholine receptor M4. Compounds, pharmaceutical salts of compounds, and pharmaceutical compositions of the present invention are directed to methods useful in the treatment or prophylaxis of a neurological disease, disorder, or symptom, and conditions related thereto.

Classes IPC  ?

• C07D 403/14 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant au moins trois hétérocycles
• A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• C07D 495/04 - Systèmes condensés en ortho

Produits et services

Printed questionnaires in the nature of assessments in the field of healthcare; printed questionnaires in the nature of assessments in the field of tardive dyskinesia

Abrégé

The present application is related to methods of preparing pharmaceutical compositions comprising a VMAT2 inhibitor and/or identifying therapeutically effective dosages of a VMAT2 inhibitor, wherein the VMAT2 inhibitor is useful for treating neurological and psychiatric diseases and disorders and for achieving an occupancy rate between 80-96% in a subject.

Classes IPC  ?

• A61K 51/04 - Composés organiques

Abrégé

Provided herein are methods for treatment of chorea associated with Huntington's disease using a vesicular monoamine transporter isoform 2 (VMAT2) inhibitor. In certain embodiments, the VMAT2 inhibitor is valbenazine or a pharmaceutically acceptable salt thereof.

Classes IPC  ?

• A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61P 25/14 - Médicaments pour le traitement des troubles du système nerveux pour traiter les mouvements anormaux, p. ex. chorée, dyskinésie

Abrégé

Provided herein are methods for treatment of chorea associated with Huntington's disease using a vesicular monoamine transporter isoform 2 (VMAT2) inhibitor. In certain embodiments, the VMAT2 inhibitor is valbenazine or a pharmaceutically acceptable salt thereof.

Classes IPC  ?

• A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61P 25/14 - Médicaments pour le traitement des troubles du système nerveux pour traiter les mouvements anormaux, p. ex. chorée, dyskinésie

Abrégé

This present disclosure relates to processes for preparing a compound of Formula (A) which is useful as an intermediate in the preparation of mAChR agonist compounds; and compositions comprising the compound of Formula (A).

Classes IPC  ?

• C12P 17/10 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'azote comme unique hétéro-atome du cycle
• C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)
• C12P 41/00 - Procédés utilisant des enzymes ou des micro-organismes pour la séparation d'isomères optiques à partir d'un mélange racémique

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information; Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Abrégé

SSS)-4-((1-benzylpyrrolidin-3-yl)(methyl)amino)-2-fluoro-5-methyl-N-(thiazol-4-yl)benzenesulfonamide; and uses of said crystalline forms and compositions.

Classes IPC  ?

• C07D 417/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61P 25/08 - AntiépileptiquesAnticonvulsivants

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information; Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information; Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information; Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information; Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

Pharmaceutical preparations for the treatment of adrenal insufficiency; pharmaceutical preparations for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information; Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

Pharmaceutical research and development services; conducting clinical trials for pharmaceutical preparations; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results; pharmaceutical research and development services in the field of anhedonia, major depressive disorder and mood disorders; conducting clinical trials for others for pharmaceutical preparations for the treatment and prevention of anhedonia, major depressive disorder and mood disorders; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations for the treatment and prevention of anhedonia, major depressive disorder and mood disorders, and evaluating epidemiological results for treatments for anhedonia, major depressive disorder and mood disorders; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials pertaining to therapies and treatments for anhedonia, major depressive disorder and mood disorders Providing medical information; providing medical information relating to therapies and treatments for anhedonia, major depressive disorder and mood disorders

Produits et services

Pharmaceutical research and development services; conducting clinical trials for pharmaceutical preparations; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results; pharmaceutical research and development services in the field of anhedonia, major depressive disorder and mood disorders; conducting clinical trials for others for pharmaceutical preparations for the treatment and prevention of anhedonia, major depressive disorder and mood disorders; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations for the treatment and prevention of anhedonia, major depressive disorder and mood disorders, and evaluating epidemiological results for treatments for anhedonia, major depressive disorder and mood disorders; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials pertaining to therapies and treatments for anhedonia, major depressive disorder and mood disorders Providing medical information; providing medical information relating to therapies and treatments for anhedonia, major depressive disorder and mood disorders

Produits et services

Pharmaceutical research and development services; conducting clinical trials for pharmaceutical preparations; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results; pharmaceutical research and development services in the field of anhedonia, major depressive disorder and mood disorders; conducting clinical trials for others for pharmaceutical preparations for the treatment and prevention of anhedonia, major depressive disorder and mood disorders; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations for the treatment and prevention of anhedonia, major depressive disorder and mood disorders, and evaluating epidemiological results for treatments for anhedonia, major depressive disorder and mood disorders; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials pertaining to therapies and treatments for anhedonia, major depressive disorder and mood disorders Providing medical information; providing medical information relating to therapies and treatments for anhedonia, major depressive disorder and mood disorders

Produits et services

Administering a patient support program to coordinate access to medicines; administering a patient support program to provide pharmaceutical co-pay assistance; administering a patient support program to provide general education and support and information about available resources for patients, caregivers and healthcare providers; administering a patient support program to provide and assist with insurance coverage and reimbursement information; Promoting awareness of congenital adrenal hyperplasia and providing a public platform to discuss congenital adrenal hyperplasia and coping strategies; Promoting awareness of adrenal insufficiency and providing a public platform to discuss adrenal insufficiency and coping strategies; Promoting awareness of endocrine diseases and disorders and providing a public platform to discuss endocrine diseases and disorders and coping strategies; promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy; promoting the interests of people who have adrenal insufficiency and their families and health care providers by means of public advocacy; promoting the interests of people who have endocrine diseases and disorders and their families and health care providers by means of public advocacy; maintaining a registry of patients with congenital adrenal hyperplasia; maintaining a registry of patients with adrenal insufficiency; maintaining a registry of patients with endocrine diseases and disorders; updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia; updating and maintenance of information in registries, namely, administering a patient registry for patients with adrenal insufficiency; updating and maintenance of information in registries, namely, administering a patient registry for patients with endocrine diseases and disorders Providing an online forum in the field of health and pharmaceuticals Educational services; providing mentorship programs in the field of health and pharmaceuticals Providing information about medical research; providing medical research information in the field of pharmaceuticals and congenital adrenal hyperplasia; providing medical research information in the field of pharmaceuticals and adrenal insufficiency; providing medical research information in the field of pharmaceuticals and endocrine diseases and disorders; creating an online community for users for the purpose of participating in discussions in the fields of health, pharmaceuticals, and coping strategies Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia; providing medical information to patients, medical professionals, and insurance companies in the field of adrenal insufficiency; providing medical information to patients, medical professionals, and insurance companies in the field of endocrine diseases and disorders; online information services, namely, providing medical information in the field of congenital adrenal hyperplasia; online information services, namely, providing medical information in the field of adrenal insufficiency; online information services, namely, providing medical information in the field of endocrine diseases and disorders; Providing an in-person health forum for users to participate in discussions in the field of congenital adrenal hyperplasia; Providing an in-person health forum for users to participate in discussions in the field of adrenal insufficiency; Providing an in-person health forum for users to participate in discussions in the field of endocrine diseases and disorders Downloadable children's books; downloadable children's booklets; downloadable children's activity books; downloadable newsletters; downloadable computer software games Printed children's books; printed children's booklets; printed activity books; printed newsletters in the field of endocrine diseases and disorders

Produits et services

Administering a patient support program to coordinate access to medicines; administering a patient support program to provide pharmaceutical co-pay assistance; administering a patient support program to provide general education and support and information about available resources for patients, caregivers and healthcare providers; administering a patient support program to provide and assist with insurance coverage and reimbursement information; Promoting awareness of congenital adrenal hyperplasia and providing a public platform to discuss congenital adrenal hyperplasia and coping strategies; Promoting awareness of adrenal insufficiency and providing a public platform to discuss adrenal insufficiency and coping strategies; Promoting awareness of endocrine diseases and disorders and providing a public platform to discuss endocrine diseases and disorders and coping strategies; promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy; promoting the interests of people who have adrenal insufficiency and their families and health care providers by means of public advocacy; promoting the interests of people who have endocrine diseases and disorders and their families and health care providers by means of public advocacy; maintaining a registry of patients with congenital adrenal hyperplasia; maintaining a registry of patients with adrenal insufficiency; maintaining a registry of patients with endocrine diseases and disorders; updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia; updating and maintenance of information in registries, namely, administering a patient registry for patients with adrenal insufficiency; updating and maintenance of information in registries, namely, administering a patient registry for patients with endocrine diseases and disorders Providing an online forum in the field of health and pharmaceuticals Educational services; providing mentorship programs in the field of health and pharmaceuticals Providing information about medical research; providing medical research information in the field of pharmaceuticals and congenital adrenal hyperplasia; providing medical research information in the field of pharmaceuticals and adrenal insufficiency; providing medical research information in the field of pharmaceuticals and endocrine diseases and disorders; creating an online community for users for the purpose of participating in discussions in the fields of health, pharmaceuticals, and coping strategies Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia; providing medical information to patients, medical professionals, and insurance companies in the field of adrenal insufficiency; providing medical information to patients, medical professionals, and insurance companies in the field of endocrine diseases and disorders; online information services, namely, providing medical information in the field of congenital adrenal hyperplasia; online information services, namely, providing medical information in the field of adrenal insufficiency; online information services, namely, providing medical information in the field of endocrine diseases and disorders; Providing an in-person health forum for users to participate in discussions in the field of congenital adrenal hyperplasia; Providing an in-person health forum for users to participate in discussions in the field of adrenal insufficiency; Providing an in-person health forum for users to participate in discussions in the field of endocrine diseases and disorders Downloadable children's books; downloadable children's booklets; downloadable children's activity books; downloadable newsletters; downloadable computer software games Printed children's books; printed children's booklets; printed activity books; printed newsletters in the field of endocrine diseases and disorders

Abrégé

NSNN-prop-2-ynyl-1,3-thiazol-2-amine, or a pharmaceutically acceptable salt thereof, in a pediatric subject having congenital adrenal hyperplasia.

Classes IPC  ?

• A61K 31/426 - 1,3-Thiazoles
• A61K 31/573 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p. ex. prégnane ou progestérone substitués en position 21, p. ex. cortisone, dexaméthasone, prednisone ou aldostérone
• A61P 5/38 - Médicaments pour le traitement des troubles du système endocrinien des hormones surrénales

Abrégé

Provided herein are methods for the add-on treatment of schizophrenia using a vesicular monoamine transporter isoform 2 (VMAT2) inhibitor. In certain embodiments, the VMAT2 inhibitor is valbenazine or a pharmaceutically acceptable salt thereof.

Classes IPC  ?

• A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
• A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
• A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
• A61K 31/451 - Pipéridines non condensées, p. ex. pipérocaïne ayant un carbocycle lié directement à l'hétérocycle, p. ex. glutéthimide, mépéridine, lopéramide, phencyclidine, piminodine
• A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
• A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
• A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• A61K 31/5415 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. sulthiame condensés en ortho ou en péri avec des systèmes carbocycliques, p. ex. phénothiazine, chlorpromazine, piroxicam
• A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p. ex. clozapine, dilazèpe
• A61K 31/553 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant au moins un azote et au moins un oxygène comme hétéro-atomes d'un cycle, p. ex. loxapine, staurosporine
• A61K 31/554 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. clothiapine, diltiazem

Abrégé

Provided is a method of treating dyskinesia due to cerebral palsy in a patient in need thereof, comprising: administering a vesicular monoamine transporter 2 (VMAT2) inhibitor to the patient in need thereof.

Classes IPC  ?

• A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Abrégé

NSNN-prop-2-ynyl-1,3-thiazol-2-amine, or a pharmaceutically acceptable salt thereof, in an adult subject having congenital adrenal hyperplasia.

Classes IPC  ?

• A61K 31/426 - 1,3-Thiazoles
• A61K 31/573 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p. ex. prégnane ou progestérone substitués en position 21, p. ex. cortisone, dexaméthasone, prednisone ou aldostérone
• A61P 5/38 - Médicaments pour le traitement des troubles du système endocrinien des hormones surrénales

Produits et services

Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions. Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions. Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions. Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions.

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions.

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions.

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions. Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

(1) Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Abrégé

The present disclosure provides deuterated compounds and their use as agonists of the M4 muscarinic acetylcholine receptor in the treatment or prevention of various diseases or disorders associated with the M4 receptor.

Classes IPC  ?

• C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
• C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
• A61P 25/18 - Antipsychotiques, c.-à-d. neuroleptiquesMédicaments pour le traitement de la manie ou de la schizophrénie
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

The present disclosure relates to the fields of chemistry and medicine, more particularly to processes for making 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thi-azol-2-amine (Compound 1), pharmaceutically acceptable salts, and crystalline forms thereof, for the treatment of congenital adrenal hyperplasia (CAH).

Classes IPC  ?

• A61K 31/426 - 1,3-Thiazoles
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/107 - Émulsions
• A61K 9/28 - DragéesPilules ou comprimés avec revêtements
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
• A61K 47/14 - Esters d’acides carboxyliques, p. ex. acides gras monoglycérides, triglycérides à chaine moyenne, parabènes ou esters d’acide gras de PEG
• A61K 47/22 - Composés hétérocycliques, p. ex. acide ascorbique, tocophérol ou pyrrolidones
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
• A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
• C07D 277/42 - Radicaux amino ou imino substitués par des radicaux hydrocarbonés ou par des radicaux hydrocarbonés substitués

Abrégé

The present application relates to processes for preparing (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate), which is an inhibitor of vesicular monoamine transporter 2 (VMAT2) useful in the treatment of hyperkinetic movement disorders such as tardive dyskinesia (TD).

Classes IPC  ?

• C07D 471/04 - Systèmes condensés en ortho
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
• A61K 9/50 - Microcapsules
• A61K 31/4375 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. quinolizines, naphtyridines, berbérine, vincamine

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the prevention and treatment of hormonal, genetic, and endocrine diseases, disorders, and conditions; pharmaceutical preparations for human use for the treatment of rare and orphan diseases, disorders, and conditions; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia.

Produits et services

(1) Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions. (1) Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

(1) Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions. (1) Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

(1) Pharmaceutical preparations for human use; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions. (1) Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders.

Produits et services

pharmaceutical preparations for human use; pharmaceutical preparations for the prevention and treatment of hormonal, genetic, and endocrine diseases, disorders, and conditions; pharmaceutical preparations for human use for the treatment of rare and orphan diseases, disorders, and conditions; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia

Produits et services

Promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy; maintaining a registry of patients with congenital adrenal hyperplasia; Updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia Medical and scientific research services; providing an online computer database that contains data on clinical outcomes, patient-reported outcomes, clinician-reported outcomes, and health care resource utilization for medical and scientific research purposes; providing information in the field of medical and scientific research featuring a registry of patients with congenital adrenal hyperplasia; administering a scientific advisory committee in the nature of providing scientific advice and scientific consultation relating to congenital adrenal hyperplasia Providing medical information; providing a website featuring a registry of patients with congenital adrenal hyperplasia for medical treatment purposes; providing medical and health information to consumers, patients, doctors, and caregivers in the field of congenital adrenal hyperplasia

Abrégé

The present disclosure relates to compounds of Formula (I) that modulate the activity of G-protein coupled receptor 52 (GPR52), pharmaceutically acceptable salts of compounds of Formula (I), and pharmaceutical compositions thereof. Compounds, pharmaceutical salts of compounds, and pharmaceutical compositions of the present disclosure are directed to methods useful in the treatment or prophylaxis of a neurological disease or disorder and conditions related thereto. The present disclosure relates to compounds of Formula (I) that modulate the activity of G-protein coupled receptor 52 (GPR52), pharmaceutically acceptable salts of compounds of Formula (I), and pharmaceutical compositions thereof. Compounds, pharmaceutical salts of compounds, and pharmaceutical compositions of the present disclosure are directed to methods useful in the treatment or prophylaxis of a neurological disease or disorder and conditions related thereto.

Classes IPC  ?

• C07D 213/56 - Amides
• A61K 31/4418 - Pyridines non condenséesLeurs dérivés hydrogénés ayant un carbocycle lié directement à l'hétérocycle, p. ex. cyproheptadine
• A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
• A61K 31/4725 - Isoquinoléines non condensées, p. ex. papavérine contenant d'autres hétérocycles
• C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique

Abrégé

Provided is a method of treating a neurological or psychiatric disease or disorder in a patient in need thereof, comprising: administering a vesicular monoamine transporter 2 (VMAT2) inhibitor to the patient in need thereof, the patient also being administered a strong cytochrome P450 2D6 (CYP2D6) inhibitor.

Classes IPC  ?

• A61K 31/4738 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques
• A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
• A61K 31/138 - Aryloxyalkylamines, p. ex. propranolol, tamoxifène, phénoxybenzamine
• A61K 31/4525 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'oxygène comme hétéro-atome du cycle
• A61K 31/49 - Dérivés du cinchonane, p. ex. quinine

Abrégé

Provided is a method of treating a neurological or psychiatric disease or disorder in a patient in need thereof, comprising: administering a vesicular monoamine transporter 2 (VMAT2) inhibitor to the patient in need thereof wherein the patient is a CYP2D6 poor metabolizer.

Classes IPC  ?

• A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/20 - Pilules, pastilles ou comprimés
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat

Produits et services

Pharmaceutical preparations for human use; pharmaceutical preparations for the prevention and treatment of hormonal, genetic, and endocrine diseases, disorders, and conditions; pharmaceutical preparations for human use for the treatment of rare and orphan diseases, disorders, and conditions; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia.

Abrégé

The present disclosure relates to compounds of Formula (I) capable of modulating the activity of GPR52. The present disclosure further provides a process for the preparation of compounds of Formula (1) and methods of using compounds of Formula (I) in the management of diseases or disorders associated with the activity of GPR52 including, but not limited to, the treatment of various neurological conditions.

Classes IPC  ?

• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• C07D 401/12 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
• C07D 403/12 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 405/14 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
• C07D 471/04 - Systèmes condensés en ortho
• C07D 471/08 - Systèmes pontés
• A61K 31/416 - 1,2-Diazoles condensés avec des systèmes carbocycliques, p. ex. indazole
• A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
• A61K 31/439 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle le cycle formant une partie d'un système cyclique ponté, p. ex. quinuclidine
• A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
• A61K 31/444 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. amrinone
• A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
• A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine

Abrégé

The present disclosure relates to compounds of formula (I), which are capable of modulating the activity of GPR52. The present disclosure further provides a process for the preparation of said compounds and methods of using said compounds in the management of diseases or disorders associated with the activity of GPR52 including, but not limited to, the treatment of various neurological conditions. (Formula (I))

Classes IPC  ?

• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• C07D 213/62 - Atomes d'oxygène ou de soufre
• C07D 213/72 - Atomes d'azote
• C07D 401/12 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 405/12 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• A61K 31/4418 - Pyridines non condenséesLeurs dérivés hydrogénés ayant un carbocycle lié directement à l'hétérocycle, p. ex. cyproheptadine
• A61K 31/444 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. amrinone
• A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine

Abrégé

The present disclosure relates to compounds of Formula (I) capable of modulating the activity of GPR52. The present disclosure further provides a process for the preparation of compounds of Formula (1) and methods of using compounds of Formula (I) in the management of diseases or disorders associated with the activity of GPR52 including, but not limited to, the treatment of various neurological conditions.

Classes IPC  ?

• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• C07D 213/68 - Un atome d'oxygène lié en position 4
• C07D 231/56 - BenzopyrazolesBenzopyrazoles hydrogénés
• C07D 401/12 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 405/12 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 413/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 417/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 471/04 - Systèmes condensés en ortho
• C07D 491/052 - Systèmes condensés en ortho avec un seul atome d'oxygène comme hétéro-atome du cycle contenant de l'oxygène le cycle contenant de l'oxygène étant à six chaînons
• A61K 31/444 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. amrinone
• A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
• A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
• A61K 31/443 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'oxygène comme hétéro-atome du cycle
• A61K 31/538 - 1,4-Oxazines, p. ex. morpholine condensées en ortho ou en péri avec des systèmes carbocycliques
• A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
• A61K 31/4725 - Isoquinoléines non condensées, p. ex. papavérine contenant d'autres hétérocycles
• A61K 31/4436 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un hétérocycle avec le soufre comme hétéro-atome du cycle
• A61K 31/517 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. quinazoline, périmidine
• A61K 31/498 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. quinoxaline, phénazine

Produits et services

Pharmaceutical research and development services; conducting clinical trials for others for pharmaceutical preparations; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results; pharmaceutical research and development services in the field of major depressive disorder and neurological, central nervous system, psychiatric, and mood disorders; conducting clinical trials for others for pharmaceutical preparations for the treatment and prevention of major depressive disorder and neurological, central nervous system, psychiatric, and mood disorders; pharmaceutical research services and pharmaceutical product evaluation, namely, conducting post-authorization research for the marketing of pharmaceutical preparations for the treatment and prevention of major depressive disorder and neurological, central nervous system, psychiatric, and mood disorders, and evaluating epidemiological results for treatments for major depressive disorder and neurological, central nervous system, psychiatric, and mood disorders; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials; providing medical and scientific research information to patients and practitioners in the field of clinical trials, namely, as to the results of clinical trials pertaining to therapies and treatments for major depressive disorder and neurological, central nervous system, psychiatric, and mood disorders. Providing medical information; providing medical information relating to therapies and treatments for major depressive disorder and neurological, central nervous system, psychiatric, and mood disorders.

Classes IPC  ?

• A61K 31/4375 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. quinolizines, naphtyridines, berbérine, vincamine
• A61P 25/08 - AntiépileptiquesAnticonvulsivants
• A61P 25/14 - Médicaments pour le traitement des troubles du système nerveux pour traiter les mouvements anormaux, p. ex. chorée, dyskinésie
• A61P 25/16 - Antiparkinsoniens
• A61P 25/24 - Antidépresseurs
• A61P 25/26 - Psychostimulants, p. ex. nicotine, cocaïne
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• C07D 471/04 - Systèmes condensés en ortho

Abrégé

This disclosure relates to, inter alia, certain compounds, compositions, and pharmaceutical compositions thereof, that modulate the activity of the transporter protein vesicular monoamine transporter-2 (VMAT2) and are directed to methods useful in the treatment of transporter protein vesicular monoamine transporter-2 mediated disorders, such as, neurological or psychiatric disease or disorders, including but not limited to, hyperkinetic movement disorders (e.g., tardive dyskinesia, Tourette's syndrome, Huntington's disease, tics, ataxia, chorea (such as, chorea associated with Huntington's disease), dystonia, hemifacial spasm, myoclonus, restless leg syndrome, and tremors). The disclosure further relates to synthetic methods and intermediates useful in the preparation of the compounds.

Classes IPC  ?

• C07D 471/04 - Systèmes condensés en ortho
• A61K 31/4375 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. quinolizines, naphtyridines, berbérine, vincamine
• A61P 25/08 - AntiépileptiquesAnticonvulsivants
• A61P 25/14 - Médicaments pour le traitement des troubles du système nerveux pour traiter les mouvements anormaux, p. ex. chorée, dyskinésie
• A61P 25/16 - Antiparkinsoniens
• A61P 25/24 - Antidépresseurs
• A61P 25/26 - Psychostimulants, p. ex. nicotine, cocaïne
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Produits et services

Promoting awareness of tardive dyskinesia; Promoting the interests of people who have tardive dyskinesia and their families and health care providers by means of public advocacy Providing healthcare information for patients and caregivers in the field of tardive dyskinesia; Providing healthcare information for healthcare providers in the field of tardive dyskinesia; Providing medical information; Providing medical information for patients and caregivers in the field of tardive dyskinesia; Providing medical information for healthcare providers in the field of tardive dyskinesia; Online information services, namely, providing medical information in the field of tardive dyskinesia

Produits et services

Promoting awareness of Huntington's disease and chorea associated with Huntington's disease; Promoting the interests of people who have Huntington's disease and chorea associated with Huntington's disease and their families and health care providers by means of public advocacy Providing healthcare information for patients and caregivers in the field of Huntington's disease and chorea associated with Huntington's disease; Providing medical information; providing medical information for patients and caregivers in the field of Huntington's disease and chorea associated with Huntington's disease; Online information services, namely, providing medical information in the field of Huntington's disease and chorea associated with Huntington's disease

Produits et services

Promoting awareness of congenital adrenal hyperplasia and promoting awareness of congenital adrenal hyperplasia by providing a public in-person platform to discuss congenital adrenal hyperplasia and coping strategies; Promoting awareness of adrenal insufficiency and promoting awareness of adrenal insufficiency by providing a public in-person platform to discuss adrenal insufficiency and coping strategies; Promoting awareness of endocrine diseases and disorders and promoting awareness of endocrine diseases and disorders by providing a public in-person platform to discuss endocrine diseases and disorders and coping strategies; promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy; promoting the interests of people who have adrenal insufficiency and their families and health care providers by means of public advocacy; promoting the interests of people who have endocrine diseases and disorders and their families and health care providers by means of public advocacy; maintaining a registry of patients with congenital adrenal hyperplasia; maintaining a registry of patients with adrenal insufficiency; maintaining a registry of patients with endocrine diseases and disorders; updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia; updating and maintenance of information in registries, namely, administering a patient registry for patients with adrenal insufficiency; updating and maintenance of information in registries, namely, administering a patient registry for patients with endocrine diseases and disorders Promoting awareness of congenital adrenal hyperplasia by providing a public online platform in the nature of an online forum to discuss congenital adrenal hyperplasia and coping strategies; Promoting awareness of adrenal insufficiency by providing a public online platform in the nature of an online forum to discuss adrenal insufficiency and coping strategies; Promoting awareness of endocrine diseases and disorders by providing a public online platform in the nature of an online forum to discuss endocrine diseases and disorders and coping strategies Providing information about medical research; providing medical research information in the field of pharmaceuticals and congenital adrenal hyperplasia; providing medical research information in the field of pharmaceuticals and adrenal insufficiency; providing medical research information in the field of pharmaceuticals and endocrine diseases and disorders Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia; providing medical information to patients, medical professionals, and insurance companies in the field of adrenal insufficiency; providing medical information to patients, medical professionals, and insurance companies in the field of endocrine diseases and disorders; online information services, namely, providing medical information in the field of congenital adrenal hyperplasia; online information services, namely, providing medical information in the field of adrenal insufficiency; online information services, namely, providing medical information in the field of endocrine diseases and disorders; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of congenital adrenal hyperplasia; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of adrenal insufficiency; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of endocrine diseases and disorders

Produits et services

Promoting awareness of congenital adrenal hyperplasia and promoting awareness of congenital adrenal hyperplasia by providing a public in-person platform to discuss congenital adrenal hyperplasia and coping strategies; Promoting awareness of adrenal insufficiency and promoting awareness of adrenal insufficiency by providing a public in-person platform to discuss adrenal insufficiency and coping strategies; Promoting awareness of endocrine diseases and disorders and promoting awareness of endocrine diseases and disorders by providing a public in-person platform to discuss endocrine diseases and disorders and coping strategies; promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy; promoting the interests of people who have adrenal insufficiency and their families and health care providers by means of public advocacy; promoting the interests of people who have endocrine diseases and disorders and their families and health care providers by means of public advocacy; maintaining a registry of patients with congenital adrenal hyperplasia; maintaining a registry of patients with adrenal insufficiency; maintaining a registry of patients with endocrine diseases and disorders; updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia; updating and maintenance of information in registries, namely, administering a patient registry for patients with adrenal insufficiency; updating and maintenance of information in registries, namely, administering a patient registry for patients with endocrine diseases and disorders Promoting awareness of congenital adrenal hyperplasia by providing a public online platform in the nature of an online forum to discuss congenital adrenal hyperplasia and coping strategies; Promoting awareness of adrenal insufficiency by providing a public online platform in the nature of an online forum to discuss adrenal insufficiency and coping strategies; Promoting awareness of endocrine diseases and disorders by providing a public online platform in the nature of an online forum to discuss endocrine diseases and disorders and coping strategies Providing information about medical research; providing medical research information in the field of pharmaceuticals and congenital adrenal hyperplasia; providing medical research information in the field of pharmaceuticals and adrenal insufficiency; providing medical research information in the field of pharmaceuticals and endocrine diseases and disorders Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia; providing medical information to patients, medical professionals, and insurance companies in the field of adrenal insufficiency; providing medical information to patients, medical professionals, and insurance companies in the field of endocrine diseases and disorders; online information services, namely, providing medical information in the field of congenital adrenal hyperplasia; online information services, namely, providing medical information in the field of adrenal insufficiency; online information services, namely, providing medical information in the field of endocrine diseases and disorders; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of congenital adrenal hyperplasia; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of adrenal insufficiency; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of endocrine diseases and disorders

Produits et services

Promoting awareness of congenital adrenal hyperplasia and promoting awareness of congenital adrenal hyperplasia by providing a public in-person platform to discuss congenital adrenal hyperplasia and coping strategies; Promoting awareness of adrenal insufficiency and promoting awareness of adrenal insufficiency by providing a public in-person platform to discuss adrenal insufficiency and coping strategies; Promoting awareness of endocrine diseases and disorders and promoting awareness of endocrine diseases and disorders by providing a public in-person platform to discuss endocrine diseases and disorders and coping strategies; promoting the interests of people who have congenital adrenal hyperplasia and their families and health care providers by means of public advocacy; promoting the interests of people who have adrenal insufficiency and their families and health care providers by means of public advocacy; promoting the interests of people who have endocrine diseases and disorders and their families and health care providers by means of public advocacy; maintaining a registry of patients with congenital adrenal hyperplasia; maintaining a registry of patients with adrenal insufficiency; maintaining a registry of patients with endocrine diseases and disorders; updating and maintenance of information in registries, namely, administering a patient registry for patients with congenital adrenal hyperplasia; updating and maintenance of information in registries, namely, administering a patient registry for patients with adrenal insufficiency; updating and maintenance of information in registries, namely, administering a patient registry for patients with endocrine diseases and disorders Promoting awareness of congenital adrenal hyperplasia by providing a public online platform in the nature of an online forum to discuss congenital adrenal hyperplasia and coping strategies; Promoting awareness of adrenal insufficiency by providing a public online platform in the nature of an online forum to discuss adrenal insufficiency and coping strategies; Promoting awareness of endocrine diseases and disorders by providing a public online platform in the nature of an online forum to discuss endocrine diseases and disorders and coping strategies Providing information about medical research; providing medical research information in the field of pharmaceuticals and congenital adrenal hyperplasia; providing medical research information in the field of pharmaceuticals and adrenal insufficiency; providing medical research information in the field of pharmaceuticals and endocrine diseases and disorders Providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia; providing medical information to patients, medical professionals, and insurance companies in the field of adrenal insufficiency; providing medical information to patients, medical professionals, and insurance companies in the field of endocrine diseases and disorders; online information services, namely, providing medical information in the field of congenital adrenal hyperplasia; online information services, namely, providing medical information in the field of adrenal insufficiency; online information services, namely, providing medical information in the field of endocrine diseases and disorders; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of congenital adrenal hyperplasia; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of adrenal insufficiency; Providing medical information in the nature of providing an in-person health forum for users to participate in discussions in the field of endocrine diseases and disorders

Abrégé

CRF1 receptor antagonists have the potential to directly inhibit ACTH release in patients with CAH and thereby allow normalization of androgen production while using lower, more physiologic doses of hydrocortisone, and thus reducing treatment-associated side effects.

Classes IPC  ?

• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• A61K 31/427 - Thiazoles non condensés et contenant d'autres hétérocycles
• A61K 31/4985 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes hétérocycliques

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results providing medical information; providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

Providing medical research information; providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders, for others; conducting post-authorization pharmaceutical research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information; Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Abrégé

Provided are methods related to treating congenital adrenal hyperplasia in a subject in need thereof comprising administering to the subject a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Classes IPC  ?

• A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
• A61K 47/22 - Composés hétérocycliques, p. ex. acide ascorbique, tocophérol ou pyrrolidones
• A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
• A61K 9/16 - AgglomérésGranulésMicrobilles
• A61K 9/20 - Pilules, pastilles ou comprimés
• A61K 9/10 - DispersionsÉmulsions
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
• A61P 5/00 - Médicaments pour le traitement des troubles du système endocrinien

Produits et services

(1) Providing medical research information in the field of pharmaceuticals and clinical trials focusing on Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders; Conducting research in the field of pharmaceuticals for evaluating epidemiological results; Conducting research in the field of pharmaceuticals for evaluating patients in the field of Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders (2) Providing medical information to patients, medical professionals, and insurance companies in the field of Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders; Online information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders; Providing pharmaceutical consultancy services

Produits et services

Providing medical research information in the field of pharmaceuticals and clinical trials focusing on Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders; Scientific research in the nature of conducting clinical trials for pharmaceutical preparations for the treatment of Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders, for others; Conducting research in the field of pharmaceuticals for evaluating epidemiological results; Conducting research in the field of pharmaceuticals for evaluating patients in the field of Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders Providing medical information to patients, medical professionals, and insurance companies in the field of Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders; Online information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of Huntington's disease, chorea associated with Huntington's disease, chorea, and neurodegenerative and movement disorders; Providing pharmaceutical consultancy services

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions Providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

(1) Pharmaceutical preparations for the diagnosis, prevention and treatment of hormonal, genetic and endocrine disorders and conditions; pharmaceuticals for human use for the treatment of rare and orphan diseases, disorders and conditions; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia.

Produits et services

pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Produits et services

pharmaceutical preparations for human use for the treatment of adrenal insufficiency; pharmaceutical preparations for human use for the treatment of hormonal and genetic diseases, disorders and conditions; pharmaceutical preparations for the diagnosis, prevention and treatment of endocrine diseases and disorders; pharmaceutical preparations for the treatment of congenital adrenal hyperplasia; pharmaceuticals for human use for the treatment of rare and orphan hormonal and genetic diseases, disorders and conditions providing medical research information in the field of pharmaceuticals and clinical trials focusing on congenital adrenal hyperplasia and other endocrine diseases and disorders; Conducting clinical trials for pharmaceutical preparations for the treatment of congenital adrenal hyperplasia and other endocrine diseases and disorders; conducting post-authorization research for the marketing of pharmaceutical preparations and evaluating epidemiological results Providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders; on-line information services, namely, providing medical information to patients, medical professionals, and insurance companies in the field of congenital adrenal hyperplasia and other endocrine diseases and disorders

Abrégé

This disclosure relates generally to VMAT2 inhibitor compounds of Formula (Ia): and pharmaceutically acceptable salts thereof, as well as compositions and methods related thereto.

Classes IPC  ?

• C07D 471/14 - Systèmes condensés en ortho
• A61P 25/18 - Antipsychotiques, c.-à-d. neuroleptiquesMédicaments pour le traitement de la manie ou de la schizophrénie
• C07D 471/04 - Systèmes condensés en ortho